LOCUS       NZ_NUEG01000031        23216 bp    DNA     linear   CON 30-JUL-2024
DEFINITION  Bacillus wiedmannii strain AFS005864
            AFS005864_61_A10_Contig16_140312, whole genome shotgun sequence.
ACCESSION   NZ_NUEG01000031
VERSION     NZ_NUEG01000031.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus wiedmannii
  ORGANISM  Bacillus wiedmannii
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 124484)
  AUTHORS   Bleich,R.M., Kirk,G.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Large-scale bioinformatics analysis of Bacillus genomes uncovers
            conserved roles of natural products in bacterial physiology
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 124484)
  AUTHORS   Bleich,R.M., Kirk,G.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Direct Submission
  JOURNAL   Submitted (07-SEP-2017) Chemical Biology and Medicinal Chemistry,
            UNC Chapel Hill, 125 Mason Farm Rd., Chapel Hill, NC 17599, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Assembly Cell v. 4.2.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 37.62x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002555855.1-RS_2024_07_30
            Annotation Date                   :: 07/30/2024 04:09:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,628
            CDSs (total)                      :: 5,554
            Genes (coding)                    :: 5,373
            CDSs (with protein)               :: 5,373
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 181
            CDSs (without protein)            :: 181
            Pseudo Genes (ambiguous residues) :: 0 of 181
            Pseudo Genes (frameshifted)       :: 56 of 181
            Pseudo Genes (incomplete)         :: 126 of 181
            Pseudo Genes (internal stop)      :: 39 of 181
            Pseudo Genes (multiple problems)  :: 35 of 181
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:21:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 71548
            Orig. end                         :: 94764
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NUEG01000031.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23216
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23216
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23216
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13216](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13216
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(1141..1668)
                     /locus_tag="CN905_RS18865"
                     /old_locus_tag="CN905_18865"
     CDS             complement(1141..1668)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002134708.1"
                     /locus_tag="CN905_RS18865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18865"
                     /product="permease"
                     /protein_id="WP_141521026.1"
                     /transl_table=11
                     /translation="MKELKRYRFFFILLLGLIVLTFINQSLGWSALQLTGNSILDMLFL
                     LPPVLIFVGLLDQWVKKETLMKYMGENSGVYGILFSLLLGGIAAGPLYIAFPIAALLLQ
                     KGASIRYIVFFLGVWTTAKLPILVYEFSSFGATFTLIHIGFGLVFFYVMGIIFERFYDQ
                     GQLLRYDVTKEM"
     gene            complement(1665..2147)
                     /locus_tag="CN905_RS18870"
                     /old_locus_tag="CN905_18870"
     CDS             complement(1665..2147)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000606976.1"
                     /locus_tag="CN905_RS18870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18870"
                     /product="hypothetical protein"
                     /protein_id="WP_097994004.1"
                     /transl_table=11
                     /translation="MINGVILYTLAIIFTGISFMKDRNKTKDALMKSWKMFCNLLPAML
                     SIMLFVGLSLSILTPSFISSIIGEQSGFIGIIYSAILGSVALIPSFVVFPLGNTLVQHG
                     AGLPQVAALMSTLMSVGITTLPMEQKIFGRSFAYARNASALLMSLLFSYIIWVVMV"
     gene            complement(2140..2481)
                     /locus_tag="CN905_RS18875"
                     /old_locus_tag="CN905_18875"
     CDS             complement(2140..2481)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002186552.1"
                     /locus_tag="CN905_RS18875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18875"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_098085662.1"
                     /transl_table=11
                     /translation="MKHTGRHTGAFLLLFLAEGDNYGGQLLQKCEEELPVNPIDSAILY
                     RTLKKLENEGAIESYVSTDHQDKPRKMYKITPAGKGQLADFQMDIEEKMKNLSFFIDKY
                     KDLKDPDHD"
     CDS             2473..2541
                     /gene="allorf_074021_074089"
                     /locus_tag="allorf_074021_074089"
                     /protein_id="allorf_074021_074089"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MFHGYTSLNELGFILLMTVYCC"
     CDS_motif       2473..2523
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MFHGYTSLNELGFILLM"
                     /locus_tag="allorf_074021_074089_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       2524..2541
                     /prepeptide="core"
                     /locus_tag="allorf_074021_074089_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.70"
                     /molecular_weight="569.7"
                     /monoisotopic_mass="569.2"
                     /core_sequence="TVYCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MFHGYTSLNELGFILLM"
                     /leader_location="[2472:2523](+)"
     gene            complement(2887..>3399)
                     /locus_tag="CN905_RS18885"
                     /old_locus_tag="CN905_18885"
                     /pseudo=""
     CDS             complement(2887..>3399)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384580.1"
                     /locus_tag="CN905_RS18885"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="CN905_18885"
                     /product="TrmB family transcriptional regulator
                     sugar-binding domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="TYEGISDSLKKLETSEEKTDNRVITLKDNKTIISYCQTLIKKAAQ
                     RIVISM"
     gene            complement(3515..4120)
                     /locus_tag="CN905_RS18890"
                     /old_locus_tag="CN905_18890"
     CDS             complement(3515..4120)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016113518.1"
                     /locus_tag="CN905_RS18890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18890"
                     /product="response regulator transcription factor"
                     /protein_id="WP_060489073.1"
                     /transl_table=11
                     /translation="MNILLIDDHALFAKSLEIALEDYSEIDQFHSLQNIENVITIINEF
                     KPDITLLDINLSNISSEDGLEVAKIILDSKCDTKIVILTGYDLPVYQYEAQKLGVSGFI
                     NKNILPEALLQILNEINKGAYHFPISTENVEELTNSEKQILQLLCDGYKRKEIASMLYA
                     SERTVSNHIQHVFDKLDVSSSLEAVTKGIKLGYIQPNY"
     gene            complement(4098..5687)
                     /locus_tag="CN905_RS18895"
                     /old_locus_tag="CN905_18895"
     CDS             complement(4098..5687)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761142.1"
                     /locus_tag="CN905_RS18895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18895"
                     /product="ATP-binding protein"
                     /protein_id="WP_097917521.1"
                     /transl_table=11
                     /translation="MKKYYEQKQILILINQLCMIIFLCYEFSTNTIVGTAKLLPLMLIT
                     IMSTYGAYISFVNLKNNNTLSQFSNLIFFASWQFLLTLHEEPIFQTLSMLLSVLILYQI
                     VQFLLLFFFQNSTYDYKKVKDWILQIICLLTLVANLISDRIFSILYSFQWLISFSCIIF
                     LFLQHRKRISFVFKNEKKHLLKSVTVLILPFILYAVFFAERPEYLSNLGWYIIILLPLF
                     SIHAIAFKNHISMRKYFLLKKSKIALMFLCFLIFISLLGVLFKFNMITYFIIIHTIIWF
                     IELYFTLLFQDTKNTISNLNTEKLKTLPKNSYVHNLIQIAKEEKLKSSFSDYLHDEILQ
                     DILAVKNMMNKSSKKEIHEIIVETLDNLNHSIRMQMQEYHPTLLKTLTLKENYGNLLEM
                     IQQKYKMKNIDISFKCNEDLFLVEPYHLVVYRILKELATNAFKHSQCSKLMLHLTQEND
                     EIKLVVKDNGKGLSPTQTNILIEHRGLNSIKEQLFLLNGKMTISDYNPSGLCITILIPM
                     KGDDSYEHFINR"
     misc_feature    complement(5679..5692)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.3"
                     /tool="antismash"
     gene            complement(5767..7737)
                     /locus_tag="CN905_RS18900"
                     /old_locus_tag="CN905_18900"
     CDS             complement(5767..7737)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1243: ABC
                     transporter, permease component"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522539.1"
                     /locus_tag="CN905_RS18900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18900"
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_097994000.1"
                     /transl_table=11
                     /translation="MGLFTIAKKNLKNNFSFYSFYFISVAFVLMVFFSFISFSMNDIVM
                     EKISSDGRVETMSKTVAIFVMAFVLFYMSYSNTFFMKKRMKELGIYSLLGYRKSTMLKL
                     LTFENIIICLAALLVGIAFGSIVHKGIVAAIITLLKLQIDTSKVPLINPNAVLFTFTFI
                     FAVLSVLSLSNWIILRKSSLLNLVRMEKKEEKKVKIKTSFSLLGLFLILIGYYLAIDIT
                     RGTESLWKTIGFSPIALLTMLSVILGTIFFIHSFLPYVIQKLKKNKTWFYKESNIIIIP
                     NFIFKIRSKAKTLILLTLLTAGTLAIFSSTLLTLYYPVAATERIVPSAIEFPLEDKELT
                     NKAIKTVQDTFGKEDTKYTETTIIHGESNSTNLPKEYSIKKEHGFDLISESAYRKLIHI
                     QDKKVEFDNLAKNESILVKYRPEKENIDKGKIYTLNLAPTTNVDVKIKETTLLNPIGFA
                     NSVGTLIISDQLYKEITTLGLTEKTIISFNGVDMRDNKEVYEKLAPLFKDNIYFTSSYQ
                     KNDYIIQQNSSTFLLISFVTIIFFIATGSILYFHNLSSTMANKSEFIILKRMGYNKKKI
                     KRIISKEIFTLFSIPYVLGLTHSIFALIAYKTALMDDLLGKSSAFVLPILFAVIIFTVV
                     YIVYYLLTKRACYKIIFNKKN"
     gene            complement(7761..8516)
                     /locus_tag="CN905_RS18905"
                     /old_locus_tag="CN905_18905"
     CDS             complement(7761..8516)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000993162.1"
                     /locus_tag="CN905_RS18905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18905"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_060489079.1"
                     /transl_table=11
                     /translation="MNALVSAKNVTKIYHKNQLPGLNKVSFDIKAGEFVGIMGASGSGK
                     TTLLNILSTIDTPTDGDVFINGVNIQTLNNNKSADFRKDYLGFIFQEYFLLDSLTVKEN
                     IAVPLTLLKKSPKEIESTIENLAKRFGIFEQLEKYPSQLSGGQKQRVAAARALAKQPSI
                     LFADEPTGALDSNSATELLQKLKEVNEELQTTILMVTHDAYAASFSSRILIFKDGNIIK
                     ELRRNEQNRKEFFEEILKEISKIDENRYN"
     misc_feature    complement(8683..8696)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.7"
                     /tool="antismash"
     misc_feature    8935..8949
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 19.24"
                     /tool="antismash"
     gene            9061..9192
                     /locus_tag="CN905_RS18910"
                     /old_locus_tag="CN905_18910"
     CDS             9061..9192
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF016486.4"
                     /locus_tag="CN905_RS18910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18910"
                     /product="type A2 lanthipeptide"
                     /protein_id="WP_060489082.1"
                     /sec_met_domain="L_biotic_A (E-value: 7.3e-11, bitscore:
                     35.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEELKSVVMTVTDEELQEAAGAAGCGWLCTVTDDCPNSVFVCC"
     CDS_motif       9061..9126
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MEELKSVVMTVTDEELQEAAGA"
                     /locus_tag="CN905_RS18910_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9127..9192
                     /prepeptide="core"
                     /locus_tag="CN905_RS18910_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="0.60"
                     /molecular_weight="2139.5"
                     /monoisotopic_mass="2137.9"
                     /core_sequence="AGCGWLCTVTDDCPNSVFVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEELKSVVMTVTDEELQEAAGA"
                     /leader_location="[9060:9126](+)"
     misc_feature    complement(9231..9244)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 25.42"
                     /tool="antismash"
     gene            9276..9407
                     /locus_tag="CN905_RS18915"
                     /old_locus_tag="CN905_18915"
     CDS             9276..9407
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF016486.4"
                     /locus_tag="CN905_RS18915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18915"
                     /product="type A2 lanthipeptide"
                     /protein_id="WP_060489084.1"
                     /sec_met_domain="L_biotic_A (E-value: 1.4e-10, bitscore:
                     34.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEELKGVVMTVTDEELQEAAGAAGCGWLCTVTDDCPNSVFVCC"
     CDS_motif       9276..9341
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MEELKGVVMTVTDEELQEAAGA"
                     /locus_tag="CN905_RS18915_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9342..9407
                     /prepeptide="core"
                     /locus_tag="CN905_RS18915_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="0.60"
                     /molecular_weight="2139.5"
                     /monoisotopic_mass="2137.9"
                     /core_sequence="AGCGWLCTVTDDCPNSVFVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEELKGVVMTVTDEELQEAAGA"
                     /leader_location="[9275:9341](+)"
     CDS             complement(9462..9614)
                     /gene="allorf_081010_081162"
                     /locus_tag="allorf_081010_081162"
                     /protein_id="allorf_081010_081162"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MIARFIINNFKLATYKYAIXXXXXCNSSSVTVITTLFNSSIPSPP
                     LIPNI"
     CDS_motif       complement(9561..9614)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MIARFIINNFKLATYKYA"
                     /locus_tag="allorf_081010_081162_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9462..9560)
                     /prepeptide="core"
                     /locus_tag="allorf_081010_081162_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.70"
                     /molecular_weight="2653.1"
                     /monoisotopic_mass="2651.5"
                     /core_sequence="IXXXXXCNSSSVTVITTLFNSSIPSPPLIPNI"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MIARFIINNFKLATYKYA"
                     /leader_location="[9560:9614](-)"
                     /alternative_weights="2671.1"
                     /alternative_weights="2689.1"
                     /alternative_weights="2707.1"
                     /alternative_weights="2725.1"
                     /alternative_weights="2743.2"
                     /alternative_weights="2761.2"
                     /alternative_weights="2779.2"
                     /alternative_weights="2797.2"
     assembly_gap    9543..9557
                     /estimated_length=15
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     assembly_gap    9714..9790
                     /estimated_length=77
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            10001..13216
                     /locus_tag="CN905_RS18920"
                     /old_locus_tag="CN905_18920"
     CDS             10001..13216
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="CN905_RS18920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18920"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_098085665.1"
                     /sec_met_domain="DUF4135 (E-value: 2.4e-111, bitscore:
                     365.6, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 9.9e-83, bitscore:
                     270.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKQLLSKELSHWSRGLYLHERTSILGDLKEGINGAASSYIEDWC
                     KKTGIPKKFISNRLENDGLDENSFQKIIMMKENPNVLKEESWMKILEEIFSNKYIEVDD
                     NDLDSNQLNNHMFLDFVRPFLEWTKTEVSKSFEQIEESYTSKVDKVAIQCNILNAVCRN
                     LIMLAGRVLVYELNLARIEKKLHGETSEERFEYFVENYITRKEDIYKILLKYPVLARLM
                     VQTAERWKIAIFEALERFLHDYDHIHESFSGNFSKLVNIKTGIGDLHKNGRSVFILEFS
                     SDSRLVYKPRSMSIDIHFNGLLNWLNNKGAKPQFKILNVLNYGEYGWQEFVEAKECNSL
                     KEVEKFYEILGGYIAIFHILHATDMHMENIIASGEHPQFIDLESLFQNFNPVGDEAFTA
                     LQKASNELSQSVLRTALLPASLFKSGSFRSIELSGIGGHGGQRLPRAKYEFENSGTDKM
                     RLIKGIGFSKGAKNRPMYAGKEVSPEKYVDNIVRGFEEVYNIFLNNRQELLVSEGPIMS
                     FENDNVRALMRHTQSYSIMLEGAIHPENLQDGLNRVRLFDYLWRVAELNEDIVPLISSE
                     THDLLLGDVPYFQSNVNSTSVWDSRGKEVKEFYKQSALENALNRIKMLAGEDCQKQMRY
                     IRISMTTMLKRWDLKEYRNDFSNHNLLNMATSKQFIQQAIDIGDRLLESAFWGDKLEDV
                     NWIGIGASLNDRWLFTPLDASLYDGVLGVAMFYAYLGEISKNEKYTQVAKSAVQSALDF
                     LKKYDGLGSLSAFNGYASVAYVFSHLAVLWDDDTYLQKALIALSECEKWIEKDQAYDLI
                     GGVTGTLIVALRLYELTKSKKTIEIAIQCGEHLIKNAKQQREGYGWTSHLDPDTALVGL
                     SHGTAGMAWALAELYTITKDEKFLNYSKHAIAYERTMFMPDEGNWSDLRYREERKSLGI
                     VNPVQWCHGAAGVALGRLMTLPHWNDTKMEEEIRVAVATTLRDGFGGSHCQCHGDFGNL
                     EVLLVASEVLGEPDLYKNAVKIGTQVLSEVNQTGWCCGIPQNEDTPSLMLGLSGIGYGL
                     LRLAAPQKVPPVLVLGSPMGMVK"
     gene            13213..15369
                     /locus_tag="CN905_RS18925"
                     /old_locus_tag="CN905_18925"
     CDS             13213..15369
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="CN905_RS18925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18925"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_098085667.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.2e-37, bitscore:
                     121.8, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRRIPFIEQMEQSECGLCCLAMVLSYFKSEYTLWELRDRWGGGR
                     DGINLLIIKKMAESLGLEATGHRISIANIKEIELPAILHWEGNHFVVVEKFKGNKVFIL
                     DPAIGRRVLLLEEIKDALSGMCISLKPTKHLEKRKVKGSWIEYLRFLWNEPWLVSSIVV
                     FSLWVQILAIATPMFVQFIVDNVITPGGNDAYMNLLAIAIGILAVIQFVFSLLRARTLV
                     KLQTRLDWNLMSRFFERLLKLPFHFFQLRSSGDLILRANSNLIVREILSNRTVTMLLDG
                     GLVFLFLFYMFNQSVYLTMYVLAIGVLQVLLLLLSNHYTRRLSQEEILRQTHSSSYLAE
                     VLRGILVVKSEGVESQVYKQWAGLFEEQMKAARRRGFFGAYIDSILQTLRFIAPLLVLW
                     MASQEVIAQRMTVGSMFAFYTLAISFLLPLTNLITTVNQMIYMGTYFRRILDILEATPE
                     QDDHKVIDAPTLEGDIQLENVSFQYNTHASEVIKDVSLEIKSGQFVAIVGPTGSGKSTL
                     ASLLLGLYQPTKGKITFDGHNIINLDKSQFRKQIGVVTQQIHLFNRSIFNNITFHNDTL
                     SEQEVMRAAGLAEIHNDIMNLPMKYQTLLSEEGSNISGGQRQRLALARALVHDPKILLL
                     DEASSALDSKTEQKIYNNIDSLKCTKIVIAHRLSTVLRADTILVVDQGKVIERGTHEQL
                     MNLKGSYEKLYNAQLQKENMGVMV"
     gene            15366..15890
                     /locus_tag="CN905_RS18930"
                     /old_locus_tag="CN905_18930"
     CDS             15366..15890
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF020123.4"
                     /locus_tag="CN905_RS18930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18930"
                     /product="redoxin domain-containing protein"
                     /protein_id="WP_060489090.1"
                     /transl_table=11
                     /translation="MRKYIKWILLITLFLVAGGGIWAVTNPKAALEMFVDFGGINEGEE
                     MPLITGEEVNGDTTSLEKFKGEKYVLMVGKVDCEVCQKTYPVLKNLKNEHPKTNFIMIG
                     QGDKNEYAQTKQKNGFEFPIISADSKISEEMNLKIYPVFYLVNEKGEVEKRSNGFEEPE
                     LQEMLRKAEKN"
     gene            15887..16312
                     /locus_tag="CN905_RS30125"
                     /old_locus_tag="CN905_18935"
     CDS             15887..16312
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019499.4"
                     /locus_tag="CN905_RS30125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18935"
                     /product="vitamin K epoxide reductase family protein"
                     /protein_id="WP_098085668.1"
                     /transl_table=11
                     /translation="MNKRVQITLVQIISILGFLLSVYLYISHLSSSFFCPVGDCLKVNS
                     SSYAQIKGVPISTLGILYYLLLHIFTYCGKKVFVIKLIKYWLLLGLVFSLYLTYLEIFE
                     IKAICIWCMVSFGLIIIGSIIVFFNSKKDIVENKRYT"
     gene            complement(16763..16888)
                     /locus_tag="CN905_RS18940"
                     /old_locus_tag="CN905_18940"
     CDS             complement(16763..16888)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002170647.1"
                     /locus_tag="CN905_RS18940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18940"
                     /product="YjcZ family sporulation protein"
                     /protein_id="WP_000540377.1"
                     /transl_table=11
                     /translation="MGYGGSCGGGCGFGGGFALLVVLFILLIIVGASCWGGGFGC"
     CDS_motif       complement(16793..16888)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MGYGGSCGGGCGFGGGFALLVVLFILLIIVGA"
                     /locus_tag="CN905_RS18940_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16763..16792)
                     /prepeptide="core"
                     /locus_tag="CN905_RS18940_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.70"
                     /molecular_weight="854.9"
                     /monoisotopic_mass="854.3"
                     /core_sequence="SCWGGGFGC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGYGGSCGGGCGFGGGFALLVVLFILLIIVGA"
                     /leader_location="[16792:16888](-)"
     gene            17089..17334
                     /locus_tag="CN905_RS18945"
                     /old_locus_tag="CN905_18945"
     CDS             17089..17334
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016716656.1"
                     /locus_tag="CN905_RS18945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18945"
                     /product="hypothetical protein"
                     /protein_id="WP_141475405.1"
                     /transl_table=11
                     /translation="MANSEMILRLLTDLKIEQQALKEQLEKIQTAVTTLEEKSAIVEEK
                     PTTLEEKPAVAAAKQRAHSGHPTSFRAWRASAQRNS"
     CDS             17494..17646
                     /gene="allorf_089042_089194"
                     /locus_tag="allorf_089042_089194"
                     /protein_id="allorf_089042_089194"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLHIYRLYDVNLIYFSCLLFVLIHLLILFFESPIDGAFFYNCFKA
                     ETSEA"
     CDS_motif       17494..17604
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MLHIYRLYDVNLIYFSCLLFVLIHLLILFFESPIDGA"
                     /locus_tag="allorf_089042_089194_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       17605..17646
                     /prepeptide="core"
                     /locus_tag="allorf_089042_089194_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.90"
                     /molecular_weight="1520.7"
                     /monoisotopic_mass="1519.7"
                     /core_sequence="FFYNCFKAETSEA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLHIYRLYDVNLIYFSCLLFVLIHLLILFFESPIDGA"
                     /leader_location="[17493:17604](+)"
                     /alternative_weights="1538.7"
     gene            17997..18581
                     /locus_tag="CN905_RS18955"
                     /old_locus_tag="CN905_18955"
     CDS             17997..18581
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001158425.1"
                     /locus_tag="CN905_RS18955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18955"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_098085670.1"
                     /transl_table=11
                     /translation="MQETKQFPLISGNLSLDLVNTELVRRGQRYDLLITDEDVLEWLHV
                     IKVNLPFWNEKTLIGIQERMNQVTSSILEAREVLRKQFEAIADRHEISNDFITYLEKQI
                     EKAPFTYKVIEQCLVSIPVGEIEDVLASLIAFDALTLIAENKLIFLKRCSNPDCVLLFI
                     DKSGKRKWCSMKICGNRKKVAKFQVRKSEEV"
     gene            18700..19254
                     /locus_tag="CN905_RS18960"
                     /old_locus_tag="CN905_18960"
     CDS             18700..19254
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002150189.1"
                     /locus_tag="CN905_RS18960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18960"
                     /product="HPP family protein"
                     /protein_id="WP_060489094.1"
                     /transl_table=11
                     /translation="MSNITAAKQKEAPPISVRYFAKMKGKGRTPLQVNIKDSLTGLLGG
                     FLTILTLTYLTSITSTELLMAPFGASCVLAFGVWNAPLSQPRNIIGGHLISTFIGLSIY
                     HLFGNEYWTIALAVGMSIAIMMLTRTTHPPAGADPIVVILGAYSWSYLVTPVLVGSLVI
                     VAFALFINNMSSKRSYPTFWI"
     gene            complement(19423..19533)
                     /locus_tag="CN905_RS18965"
                     /old_locus_tag="CN905_18965"
     CDS             complement(19423..19533)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000505686.1"
                     /locus_tag="CN905_RS18965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18965"
                     /product="YjcZ family sporulation protein"
                     /protein_id="WP_000505686.1"
                     /transl_table=11
                     /translation="MGFGGSCGGSCGFSGGFALLVVLFILLIIVGASCFC"
     CDS_motif       complement(19438..19533)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MGFGGSCGGSCGFSGGFALLVVLFILLIIVGA"
                     /locus_tag="CN905_RS18965_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(19423..19437)
                     /prepeptide="core"
                     /locus_tag="CN905_RS18965_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.70"
                     /molecular_weight="440.5"
                     /monoisotopic_mass="440.1"
                     /core_sequence="SCFC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGFGGSCGGSCGFSGGFALLVVLFILLIIVGA"
                     /leader_location="[19437:19533](-)"
     CDS             19577..19786
                     /gene="allorf_091125_091334"
                     /locus_tag="allorf_091125_091334"
                     /protein_id="allorf_091125_091334"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MFFNGFYLLYVLTHKREQVLLKIKKDTLRCLYPALMGSKTPPQNS
                     AKAKNLGGGRAAHKSPIXSFTLCN"
     CDS_motif       19577..19738
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MFFNGFYLLYVLTHKREQVLLKIKKDTLRCLYPALMGSKTPPQNSAKAKNLGGG"
                     /locus_tag="allorf_091125_091334_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       19739..19786
                     /prepeptide="core"
                     /locus_tag="allorf_091125_091334_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.70"
                     /molecular_weight="1490.7"
                     /monoisotopic_mass="1489.8"
                     /core_sequence="RAAHKSPIXSFTLCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MFFNGFYLLYVLTHKREQVLLKIKKDTLRCLYPALMGSKTP
                     PQNSAKAKNLGGG"
                     /leader_location="[19576:19738](+)"
                     /alternative_weights="1508.7"
                     /alternative_weights="1526.8"
     misc_feature    complement(19734..19748)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 18.69"
                     /tool="antismash"
     gene            complement(19783..20049)
                     /locus_tag="CN905_RS18975"
                     /old_locus_tag="CN905_18975"
     CDS             complement(19783..20049)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400943.1"
                     /locus_tag="CN905_RS18975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18975"
                     /product="YmzC family protein"
                     /protein_id="WP_060489096.1"
                     /transl_table=11
                     /translation="MENIVSRELRNIRICLIILIIVIAFWDREKPVEITDHGSDPIVNT
                     SNMTPVGDNTFAYKDESNQIKIFKFNPDTNEIKLIKEFYASEY"
     gene            20474..20932
                     /locus_tag="CN905_RS18980"
                     /old_locus_tag="CN905_18980"
     CDS             20474..20932
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198946.1"
                     /locus_tag="CN905_RS18980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18980"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_046953918.1"
                     /transl_table=11
                     /translation="MTRTYKEVINEMNRAYTELYILLFQDLKDEFGLTGQQESMLFHIN
                     LNENTTANHIATTFNISKSAVSQVLSKLEKQKMISKQVNPNNKREYFLTLGPNGSKYIE
                     RLSELDDVLIEKYFSKIDINALEQMTDTLTKINKVILEEKQKALDCNE"
     gene            20952..21485
                     /gene="pssA"
                     /locus_tag="CN905_RS18985"
                     /old_locus_tag="CN905_18985"
     CDS             20952..21485
                     /EC_number="2.7.8.8"
                     /GO_function="GO:0003882 - CDP-diacylglycerol-serine
                     O-phosphatidyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pssA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003158438.1"
                     /locus_tag="CN905_RS18985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18985"
                     /product="CDP-diacylglycerol--serine
                     O-phosphatidyltransferase"
                     /protein_id="WP_098085696.1"
                     /transl_table=11
                     /translation="MSYIPNMITIANFVCGLLAIHAVFVHDMYGAVMFIITGMVFDLFD
                     GMVARKLDSVSEIGGELDSFADLVTFGVAPSILAYSASLKDLQSIGMLCALVYSICGML
                     RLARFNTQQSKLPTFIGMPIPFAAMCLLILCLLNNPVSVEFGTCVRAYLMVSKIKFPHF
                     KKDISESLKSERWD"
     gene            21508..21879
                     /locus_tag="CN905_RS18990"
                     /old_locus_tag="CN905_18990"
     CDS             21508..21879
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620588.1"
                     /locus_tag="CN905_RS18990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18990"
                     /product="ATP synthase subunit I"
                     /protein_id="WP_060489098.1"
                     /transl_table=11
                     /translation="MIRMALRSFNIQIYCLLGVMLLGWLMTPFRAQFVGISIGLLVSMY
                     CAWILGRRIEKFGDSIVKKEKAPMLGMMNRFAAAILGAIIMYEIEHHEFMWTFAAGIMA
                     GYFLIIINLGYYSMRDAKE"
     gene            complement(21993..22097)
                     /locus_tag="CN905_RS18995"
                     /old_locus_tag="CN905_18995"
     CDS             complement(21993..22097)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000505686.1"
                     /locus_tag="CN905_RS18995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18995"
                     /product="YjcZ family sporulation protein"
                     /protein_id="WP_075310385.1"
                     /transl_table=11
                     /translation="MGFGGSCSSNCGGGFALLVVLFILLIIVGASCFC"
     CDS_motif       complement(22008..22097)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGFGGSCSSNCGGGFALLVVLFILLIIVGA"
                     /locus_tag="CN905_RS18995_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(21993..22007)
                     /prepeptide="core"
                     /locus_tag="CN905_RS18995_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.70"
                     /molecular_weight="440.5"
                     /monoisotopic_mass="440.1"
                     /core_sequence="SCFC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGFGGSCSSNCGGGFALLVVLFILLIIVGA"
                     /leader_location="[22007:22097](-)"
ORIGIN
        1 ttacaccgtt attaatgaat acgattttaa tcatttgtcc gcctgaaaaa cgtggtgcca
       61 caatgggatt aatcgcactt gtgatgatgg cagctccggc aattggccct acattatctg
      121 gagtaatcgt tgattcatta aattggcgct ggttattcta cattgttatt cctatcgtga
      181 tcatttccat tatgattgga atgaagtaca ttcaaaatgt ttcagagtta acaagaccaa
      241 aagtagatta tccatctatc cttttatcga cattaggatt tggcggactt gtgtatagct
      301 ttagtgcatc gggtgattta ggatggtctg atgcgaaagt gtatggcact ttacttattg
      361 ggcttatctc attatgtatt tttgtcgttc gacaattgaa aattgagaat ccaattttag
      421 aattacgagc atttaaagtt ccgatgttta cattatcagt tggattaatt gtcattgtga
      481 tgatgtcgtt attttcaacg atgactttat taccgatgtt cctgcaaaca gttttactcg
      541 ttacagcctt taaatcagga atcatcatgc ttccgggaag tgttattagc gccataatgg
      601 gaccaatcgc aggtaaacta tttgataaat ttagtccgaa agttattatc gttcctggta
      661 ttgtgttagt agggatagcg atgttcttat ttaaaggcat tactcctgat acatcaatgg
      721 tacagattat tgttatgcat agcgtattaa tggttggact catgtttgtc atgacagcac
      781 aaacatacgg tttaaatcaa ttaacaccag atttatatcc gcacggaaca gcactattta
      841 gtacgttaca acaagtagct ggcgcaattg gaacagctat ctttatttcg aaaatgtctt
      901 caggaacaac tcagtatatg gaaagctctg caaatccact ggatccagtg gagaaattaa
      961 acggtttaac ttctggattc caaggtgcgt ttacactagg attagtcttt attattgttg
     1021 catttatcgt atcgttgttt ttaaaagaag agaaagaggg agtaaaggca gcaagggttt
     1081 tacagaacga gaattaagat tcatataaaa aagacatctt taagagataa agatgtcttt
     1141 ttacatttct ttcgtaacat cataccttag caactgcccc tgatcataaa acctctcaaa
     1201 aataatcccc attacataga agaatacgag accgaaacca atatgaatga gtgtaaaagt
     1261 agctccaaat gaagagaatt catacacgag aattggcaat ttcgcagttg tccaaacgcc
     1321 taagaaaaat acgatgtacc gaatgcttgc gcctttttgt aagagtagtg ccgcaattgg
     1381 gaaggcaatg tagagcggac cagccgcaat accgcctaat aagagagaga ataagattcc
     1441 gtatacgccg gaattttcac ccatatattt catgagcgtt tctttcttca cccattgatc
     1501 aagtaatcct acaaatatta ggacaggggg gagtaaaaac agcatatcta aaatactatt
     1561 ccctgttaat tgtaatgcgc tccatcctaa agattgattt ataaaagtta atacaatgag
     1621 tcccagtagt aagatgaaaa agaagcgata tctttttagt tccttcatac catcaccacc
     1681 caaatgatat aggagaatag gagtgacatg agcaatgcag atgcattacg tgcgtaagca
     1741 aaacttcgtc cgaatatttt ttgttccatc ggcaaggttg taattcctac tgacatgagt
     1801 gtagacataa gtgccgcaac ttgagggagg cctgcgccgt gttggactaa tgtattaccg
     1861 agaggaaata cgacgaagct tggaataagt gcaacggagc cgagtattgc tgaataaata
     1921 ataccgataa atccagattg ctccccaata atagaagaga tgaaagacgg cgttaatata
     1981 gaaagcgata agccaacgaa aagcatgatg gagagcatcg cagggagaag gttgcaaaac
     2041 attttccacg acttcattag agcatctttc gttttattgc gatctttcat aaaagaaatc
     2101 cccgtaaaaa taatggctaa agtgtaaagg atcacgccgt taatcatggt cgggatcctt
     2161 taagtcctta tatttgtcta tgaaaaagga taagttcttc attttttctt caatatccat
     2221 ttggaaatct gccaattgtc cttttccagc aggcgtaatt ttgtacatct ttctcggttt
     2281 gtcttgatga tctgtactta cataagattc aattgcacct tcgttctcta atttttttag
     2341 cgtacgatat aaaatggcac tatcgattgg attgacggga agttcttctt cgcacttttg
     2401 cagtaattgc ccaccatagt tatcaccttc tgctaaaaat aacaaaagaa atgcacctgt
     2461 atgtcttcct gtatgtttca tggatatacc tccttgaatg aattaggatt tatactgtta
     2521 atgacagtgt actgttgtta acagtatatg gtgcatgaag tgctatgtca attttaatgt
     2581 tatatgtact gaaaaaaagg taagaaaatt tgttacgagg aaagcgtaaa tgagaatgaa
     2641 ataaaggaag cggagggtat ttaaaatgaa acgtacaaca gaattggtat taggactgat
     2701 tggtggagtt gcttccgctg tggagggaga aggggcagga gtgttatagg tttagggtga
     2761 ggagcagttg tttgtacatt agatacttct tttttagata aaataaagct tgcgattgaa
     2821 atcaaaatag ctaatccagc catatagtag ccattcgcat atgctttgtt tttttgaata
     2881 tgtttcttat tcttccataa agaaggatct tctctctgta gtaatccagt gttctaagtc
     2941 atcttggctg cgtcgggcaa gtcgatttac taaaacatca tgccacacat aatcctctaa
     3001 taggtatata tgaacggggt catctgtata aaaattaata ttacgctcct caagcgatgg
     3061 tccataaatc atctctttag aatctatcga taaaataaac caatgttctg tagagagggt
     3121 ttctgtataa gctgttatac ggtgggcttc tagattttta atggggtgca gggtaatgcc
     3181 ttgtactgtg actttatcag ctaccacaga tagatcctct tttaacgctt catacatttc
     3241 atcctacatc gaaatgacaa tacgttgtgc tgcttttttt attaatgtct gacagtagct
     3301 aatgattgtt ttgttgtctt ttaaagtaat cactcgatta tccgtttttt cctcggaagt
     3361 ttctagtttt tttaatgaat cactgattcc ttcatacgtt aaaaatcaaa aaagattaca
     3421 tagtgttggg aaccctaaag gattccccaa cactatgaaa aaaacgccta tttcatatag
     3481 acgttttttt cataagattt gctttacaat atctttaata attaggctga atatatccca
     3541 gttttatacc cttagtaaca gcttctaaag aggatgaaac atctaattta tcaaacacat
     3601 gttgaatatg attagaaact gtacgttcac tggcgtataa catagaagct atttctttac
     3661 gtttatagcc atcgcatagt aattgcaaaa tttgtttttc actattggtc aattcctcta
     3721 cattttctgt agatattgga aagtgatatg cgcctttatt aatttcattt aatatttgta
     3781 gtaacgcctc tggtaaaata ttcttattaa taaaaccact tacacctaat ttttgagctt
     3841 catactggta aacaggtaag tcataacctg tcaatataac tatttttgta tcacatttac
     3901 tatccaaaat gatttttgcc acctctaaac catcttcact gctgatgtta cttaaattaa
     3961 tatctaataa ggtgatgtct ggtttaaatt cattgataat tgtaatgaca ttttcaatat
     4021 tttgtaatga atggaattga tctatttcgg aataatcctc cagagctatt tctaagcttt
     4081 ttgcaaataa agcatggtca tctattaata aaatgttcat aggaatcgtc tcctttcatg
     4141 ggaataagaa tagtaataca taaaccagaa gggttgtaat ctgaaattgt cattttaccg
     4201 tttaataaaa atagttgttc tttaattgag ttcaatcctc tatgctcaat aagaatgttg
     4261 gtttgagtag gtgatagacc ctttccatta tcttttacta caagtttgat ttcgtcattc
     4321 tcttgtgtca aatgcaacat taactttgag cattgtgaat gtttgaatgc atttgttgcc
     4381 aattctttta aaattcggta tacaacaaga tgatagggtt caactaaaaa taaatcttca
     4441 ttacacttaa aggatatatc aatgtttttc attttatatt tttgttgtat catttcaagt
     4501 aaattgccat agttttcttt taatgtgagt gtttttaata gagttggatg atactcttgc
     4561 atttgcatgc gtattgagtg gtttaagtta tctagtgttt ctactattat ttcatgaatt
     4621 tcttttttgc tagatttatt catcatattt ttaacagcta aaatgtcttg taatatttca
     4681 tcatgtaaat aatcagaaaa actacttttt aacttttctt ctttagctat ttggataagg
     4741 ttatgcacat aagaattttt tggtaaagtt tttagtttct ctgtatttaa gttcgagata
     4801 gtgttttttg tgtcttggaa taataatgtg aaataaagtt cgatgaacca aataatggta
     4861 tgtataatta taaaataggt aatcatatta aatttaaata atactccgag taagctaatg
     4921 aaaataagga aacataaaaa cattaaagca attttacttt tttttaaaag aaaatatttt
     4981 ctcatagata tatgattttt aaaagctatt gcatgaatac taaataaagg taacaaaatt
     5041 ataatatacc atcctaagtt acttaaatat tccggacgct ctgcaaagaa aacggcatat
     5101 aaaataaaag ggaggataag aacagtaaca gatttgagca agtgcttttt ttcattttta
     5161 aaaacaaagc taattcgttt tcgatgctgg aggaatagaa aaataatgca actaaaacta
     5221 ataagccatt gaaatgaata tagaatggaa aaaatcctat cgcttatcaa gttcgcaacc
     5281 aatgttaata gacatataat ttgtaaaatc caatctttca cttttttata atcataggta
     5341 gaattttgaa aaaagaaaag gagtaaaaat tggacgattt gatataaaat taatacacta
     5401 agtagcatac taagtgtttg aaagattggt tcttcatgaa gagtgagtaa aaactgccat
     5461 gaagcgaaaa aaattaagtt agaaaattgc gataatgtgt tattgttttt taagtttaca
     5521 aaactgatat atgcaccata ggtggacatt attgttataa gcattaatgg gagcaatttt
     5581 gctgttccga caatagtatt tgttgaaaat tcgtaacata aaaaaataat catacaaagt
     5641 tgattaatta aaattaaaat ttgtttttgt tcatagtatt ttttcataaa atcacttgcc
     5701 tttactagat taaatacaga taaagctgat gtttgttgac tatcatcagc tttatctgta
     5761 gattttttaa tttttcttat taaatataat tttataacat gctctttttg ttaacaaata
     5821 ataaacgata taaacgacag taaaaataat tactgcaaaa agaataggta atacaaaggc
     5881 actgcttttc cctaatagat catccattaa agctgtttta taggctatta atgcaaaaat
     5941 actatgtgtt aatcctaata catagggaat actaaataat gtgaagattt ctttgcttat
     6001 tattcttttt atctttttct tgttatatcc cattcttttt agtattataa attcactttt
     6061 atttgccatc gtacttgaaa ggttatgaaa ataaaggata ctgcctgttg caataaaaaa
     6121 gatgatagta acaaagctaa tgagcaagaa tgttgaactg ttctgttgaa taatataatc
     6181 atttttttgg taactacttg taaaataaat attatcttta aacagtggag ctaatttttc
     6241 ataaacttct ttgttatctc tcatatctac gccattaaaa cttattatag ttttttctgt
     6301 aagtcctaga gttgttattt ctttataaag ttgatccgaa ataataagcg ttcctacact
     6361 atttgcaaag ccaattggat taagtaatgt agtctctttt atttttacat ctacgttagt
     6421 tgtaggtgct aagtttaaag tatatatttt ccctttatct atattttctt tttcaggtcg
     6481 atattttact agaatgcttt catttttagc taaattatca aactctactt ttttatcttg
     6541 aatatgtatt aacttcctgt aagctgattc agagataaga tcaaatccgt gttccttctt
     6601 tatactatat tctttaggta aatttgtaga attagattcc ccgtggataa tagttgtttc
     6661 tgtgtatttt gtatcttctt taccaaaagt atcttgtaca gttttaattg ccttattagt
     6721 taattcttta tcttccaaag gaaactcaat agctgatggc acgatacgtt ctgtagcggc
     6781 aactggatag taaagtgtca gtagagtaga actaaatatt gctaaagttc ctgcggttaa
     6841 taaggttaac aaaattaagg tttttgcttt tgaacggatt ttaaatataa agtttggaat
     6901 gataataatg tttgattcct tataaaacca tgttttattt ttcttcagct tttgaataac
     6961 atagggtaaa aaagaatgaa taaagaagat cgtccctagt attacactta acattgttag
     7021 aagagcgatt ggtgaaaacc caattgtttt ccacagggat tcagttcctc ttgtaatatc
     7081 tatagctaag taataaccga ttaaaatcaa gaataatcct agtaaggaaa agcttgtttt
     7141 aattttcact ttcttttctt ctttcttttc catgcggact aaatttagta aagaactctt
     7201 tcgaagaata atccagtttg ataaagatag cacagaaaga acagcaaaaa taaaagtaaa
     7261 agtgaatagt acagcattag gattaataag tggtacttta gaagtatcga tttgtaattt
     7321 tagtaatgta attatcgctg ccacaattcc tttatggaca atagaaccaa aagcaattcc
     7381 tacaagaaga gcagcaagac aaattataat attttcaaaa gttaacagtt ttagcattgt
     7441 tgattttcgg tatcctaaaa gtgaataaat tccaagttct ttcattcttt ttttcataaa
     7501 gaaagtatta gagtatgaca tatagaatag tacaaatgcc ataacaaaga ttgccactgt
     7561 tttggacatt gtttctactc taccatcaga cgaaattttt tccatgacaa tgtcgttcat
     7621 ggaaaaagaa ataaaggaga aaaacaccat taatacaaaa gctactgata tgaaatagaa
     7681 tgaatagaaa gaaaaattat tttttaaatt cttttttgct attgtaaata atcccacagt
     7741 cctgccttcc tttcatactc ctagttatat cgattttcat caattttaga gatttccttt
     7801 aaaatctctt caaaaaattc ttttctattt tgttcatttc ttcttaattc ttttataata
     7861 tttccatcct tgaatattaa aattctactt gaaaaacttg ctgcataggc atcatgagta
     7921 accattaaaa ttgtagtttg aagttcctcg tttacctctt ttaatttttg gagtagttct
     7981 gttgcagaat ttgaatctaa cgcgcctgta ggttcatctg caaataagat acttggctgc
     8041 ttcgcaagag ctctggctgc tgcaactctt tgtttttgtc caccagaaag ttgactaggg
     8101 tatttttcta attgctcaaa tattccaaaa cgctttgcta aattttctat tgttgattca
     8161 atttcctttg gggatttttt taacagagta agtggaacgg caatattttc ttttactgtt
     8221 aaactatcaa gcaggaaata ctcctgaaaa ataaaaccta aataatcttt cctaaaatct
     8281 gcagatttat tgttgttaag agtttggata ttgactccgt ttataaaaac atcaccatct
     8341 gtaggtgtgt cgatagtgga taagatattt aacaaagtcg tttttccaga tccagaagcc
     8401 cccataatac ccacaaactc gcccgcttta atatcaaaag atactttatt aagtcctggt
     8461 aattgatttt tgtgataaat ctttgtcaca ttttttgcag atactaatgc attcatcata
     8521 ctttctcctt tcaaattatt actacattca gtttaagagt taatatataa agattcgtga
     8581 gtaaaaaacg caatattcta ttcgtatacc ttgctctatt cttatttagt tcatctttac
     8641 tttcacaact tgcattagaa ttactaattg gtattaaaag tatttttttg aaaaaaatgc
     8701 ttttaatgta taaattttga tgtataatga atctcgcaag gacgaaaaag attgaaaaga
     8761 gagaatgtta tgatttttat tttgcgtaaa aagtaattcg ttcatgatac tcgctcctct
     8821 taatctactg ctacattaag tttatgattt aatctcaaaa ggttcgtgag taaaaagcgc
     8881 aatgttttat tcgcatacct catgctctat tttttctgaa gatcatcttt gtttccacaa
     8941 cttgtagtag aatatgaaat tggtattaaa agtattttat tgaaaaaaat gcttttaatg
     9001 tataaatttt gatgtataat gaatctcgca aggacgaagc gtagaaagga ggtgaaaaaa
     9061 atggaagagc taaaaagtgt agtaatgacg gtaacagatg aggaattaca agaagcagca
     9121 ggtgcagcag gttgcggttg gttatgtaca gtaacggatg attgtccaaa tagtgtattt
     9181 gtatgttgct aattcgaggg tttttattct gaatatttag aatttatttg tttttttata
     9241 aaattacgta ttctaaattt aagggggaaa taaaaatgga agagttaaaa ggcgtagtaa
     9301 tgacggtaac agatgaagaa ttacaagaag cagcaggtgc agcaggttgc ggttggttat
     9361 gtacagtaac agatgactgt ccaaatagcg tgtttgtatg ttgctaattt gaggtttgtt
     9421 ttattctgaa cgttatgatt aattttgatt tattattaaa actatatatt aggaattaaa
     9481 gggggtgaag ggatggaaga gttaaaaagc gtagtaatga cggtaacaga tgaggaatta
     9541 cannnnnnnn nnnnnnnaat agcgtatttg tatgttgcta gtttgaaatt atttattatg
     9601 aatcttgcaa tcatttcatt cgaaactatt gaacttatat aaaattttaa gggggaaata
     9661 aagatggaag agttaaaaag cgtagtaatg acagtaacag atgaggaatt acannnnnnn
     9721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9781 nnnnnnnnnn aatagcgtat ttgtatgttg ttagtttgat taaatgtggt gaacttaaag
     9841 acaagggtag ttaaatatat ccttgtcttt aattatgaga agtttgattc aacaatatta
     9901 cacatatgta aaaaatttaa aaatgataat tataaaggat tcattttaat agatagatga
     9961 ttaaaaatta accaattatt agcgatggga gaaaaaagta atgtcaaaac aattattatc
    10021 taaagagtta tcgcattgga gtcgtggttt atatttacat gaacgtacta gtatattagg
    10081 ggatttgaaa gagggaataa atggagcggc aagtagttac atagaagatt ggtgtaaaaa
    10141 aacaggtata ccaaaaaagt ttatttcgaa caggctagag aatgacggat tagatgagaa
    10201 ctcttttcaa aaaattatta tgatgaaaga gaatccaaat gttttaaaag aagagagctg
    10261 gatgaaaata ctggaagaaa tattttcaaa taaatatata gaggtagatg acaatgacct
    10321 agattctaat caattaaata atcatatgtt tttagacttt gtccgtccgt ttctagagtg
    10381 gacaaagaca gaggtttcca agagttttga gcagattgaa gagagctata catctaaagt
    10441 agataaagtg gctattcagt gtaatatatt aaatgctgtt tgtagaaatt taataatgtt
    10501 ggcaggaaga gttctagtat atgaattaaa cctagcacgc atagaaaaaa agttacatgg
    10561 agaaacatct gaagaacgtt ttgagtattt tgtagaaaat tatataacaa gaaaagaaga
    10621 tatttataaa attttattga agtatccggt attagctcgt ctgatggtac aaacagctga
    10681 aagatggaaa attgcaattt ttgaagcgct agagcgtttt ttacatgact atgaccatat
    10741 tcatgaatct ttctcaggca atttttctaa attagttaat attaagactg gtataggcga
    10801 tttacataaa aatggacgaa gtgtttttat tttagaattt tcaagtgata gtcgattagt
    10861 gtataaaccg agatcaatga gtattgatat tcattttaat ggattgctta attggttaaa
    10921 taataaaggt gctaaacctc agtttaaaat cttaaatgta ttaaattatg gagaatatgg
    10981 atggcaagag tttgttgagg ccaaagaatg taattcatta aaagaggttg agaaatttta
    11041 cgaaatatta ggcggatata tagcaatttt tcacatacta catgcaacgg atatgcatat
    11101 ggaaaatatc atagcatcag gagagcatcc acagtttata gatttagaat cgctatttca
    11161 aaactttaat ccagtggggg atgaggcatt tacagctctg caaaaagcat ctaatgaact
    11221 gtcacagtcg gtattacgaa cagccctttt acctgcttct ctttttaaat ccggatcgtt
    11281 tcgttctata gaattgagcg gtattggagg acatggtggt caacgtttac ctagggcgaa
    11341 atatgaattt gaaaatagcg gaaccgataa aatgagactg attaaaggga ttggcttttc
    11401 taaaggtgcc aaaaatcgcc caatgtatgc tggtaaagaa gtgtctcctg aaaaatatgt
    11461 agataatatt gttcgtggtt ttgaggaagt atacaatata tttttaaata atcgacaaga
    11521 attgttagtg agtgaagggc caattatgtc ttttgaaaat gacaatgttc gtgccttaat
    11581 gcgccatacc caatcgtatt caattatgtt ggagggagct atacatccag aaaatcttca
    11641 agatggatta aatcgtgttc gattgtttga ttatttatgg cgcgtggcag aattaaatga
    11701 agatattgta ccacttatct cttctgaaac acatgatcta ctattaggag atgtaccata
    11761 ttttcaaagt aacgtgaatt ctacttcagt ttgggatagt agaggaaaag aagttaaaga
    11821 gttttataaa cagtctgctc ttgaaaatgc tttaaataga attaaaatgc ttgctggtga
    11881 agattgtcaa aaacaaatga ggtatattcg catttcaatg acaacaatgt tgaaacgctg
    11941 ggatttgaaa gaatatcgta acgatttttc taatcataac ttactaaata tggctacatc
    12001 aaagcaattt atacaacaag cgattgatat tggggataga ttattagaat cagcgttttg
    12061 gggagataaa ttagaagatg ttaactggat tggaattggt gcttctctta atgaccgatg
    12121 gctatttacg cctttagatg catcactata tgatggggtt cttggtgttg ctatgtttta
    12181 tgcttattta ggtgaaatat caaaaaatga aaagtacaca caagttgcta aatcagccgt
    12241 acaatcagcg cttgatttct taaagaaata tgatggtcta ggctcgttgt cagcatttaa
    12301 tggatatgca tcagttgcat atgttttcag tcatttagca gtattgtggg atgatgatac
    12361 atatttacag aaggcactaa ttgcactttc agaatgtgaa aagtggatcg aaaaagatca
    12421 agcttatgat ttaattggtg gtgttacggg gacacttatc gttgcattaa gactatatga
    12481 attgactaaa tctaaaaaaa caattgaaat agcaattcaa tgtggagaac acttaattaa
    12541 aaatgctaaa cagcaacgag aaggctatgg atggacttct catcttgatc cagatactgc
    12601 actagtaggt ttatcgcatg gtacagctgg aatggcgtgg gcgttagcgg aattgtatac
    12661 cattacaaaa gatgagaaat ttttaaacta tagtaagcat gcaattgcgt atgaaagaac
    12721 gatgtttatg ccggatgaag gaaattggtc agatttacgt tatagagaag aaagaaaaag
    12781 tcttggaatt gtaaatcctg ttcaatggtg tcatggtgca gcaggtgtgg ccctaggacg
    12841 tttaatgacg cttcctcatt ggaatgatac gaaaatggaa gaagaaataa gagtagcagt
    12901 tgcaacaacc ttacgagatg gttttggtgg tagtcattgt caatgtcatg gtgattttgg
    12961 aaacttagaa gttttattgg ttgcatctga agttttgggt gagccagact tatataaaaa
    13021 tgctgttaag ataggaacgc aagttttgag tgaggtgaac caaacaggtt ggtgctgcgg
    13081 gatacctcag aacgaagaca caccaagttt gatgttagga ctatctggaa tcggctatgg
    13141 attacttcgg ttagctgctc ctcaaaaagt gccacctgta cttgtattag gaagcccaat
    13201 ggggatggtt aaatgaaaag aaggatacca tttatagaac aaatggagca atcagagtgt
    13261 ggtttgtgtt gtttagctat ggttttatca tatttcaaaa gtgagtatac attatgggaa
    13321 ttacgtgatc gttggggagg tggaagagac ggaatcaatt tacttattat aaaaaaaatg
    13381 gctgaatctt tagggttaga ggctactggt catcgaatat cgattgctaa tattaaagaa
    13441 attgaattac cagcaatctt acattgggaa ggtaatcatt ttgttgtagt tgagaagttt
    13501 aaagggaata aagtatttat tctggatcca gctataggga gacgagttct tttattagag
    13561 gaaataaagg atgcactttc aggaatgtgc atatctttaa agccaactaa gcatctagaa
    13621 aagcgaaaag taaaagggag ttggatagag tatcttcgat tcttatggaa tgagccatgg
    13681 ttagttagtt caatcgttgt attttcactg tgggtacaaa tattggcaat tgctactcca
    13741 atgtttgtgc aatttattgt tgataatgtc attacgcctg gtggaaatga tgcttacatg
    13801 aatttattag caatagcaat aggaatatta gctgtaattc aattcgtttt ctcactatta
    13861 agagcaagaa cacttgtgaa attacaaacc cgtttagatt ggaatttaat gagtagattc
    13921 tttgaaagac tattgaaatt gccatttcat tttttccaac ttcgttccag tggagattta
    13981 atattaagag caaatagtaa tttaattgta agagaaatct tgtctaatcg aaccgtaact
    14041 atgctgttag atggagggtt ggtattctta tttcttttct acatgtttaa tcagtcagta
    14101 tatcttacta tgtatgttct cgcaattggt gttttacaag tattattact gttgctaagt
    14161 aatcattaca ctcgaaggtt atctcaagag gaaattttaa gacaaaccca ttcttcaagt
    14221 tatttggctg aggttttgcg agggatttta gttgttaaat ctgaaggtgt tgaatctcaa
    14281 gtttataagc agtgggcagg tttatttgaa gaacaaatga aagcggcacg tagacgtggt
    14341 ttttttgggg catatataga tagtatatta caaaccttac gttttattgc tccattatta
    14401 gtgttatgga tggcatcaca agaagtaata gcacaacgta tgactgtagg ttctatgttt
    14461 gctttttaca cacttgcaat tagctttttg ctcccgctta caaatctaat tactacggtc
    14521 aatcagatga tttatatggg gacatatttt agacgtattt tagatattct tgaggcgact
    14581 ccagaacaag acgatcataa agttattgat gcaccaacgt tagaagggga tattcagctt
    14641 gagaatgtta gttttcaata taatacacat gcctctgaag taataaaaga cgtgtcactt
    14701 gagataaaat ctggccaatt tgtagccatt gtaggtccaa ctggttctgg aaaaagtacc
    14761 ttagcttcac tgcttttggg actttatcaa ccaacgaagg gaaaaataac ttttgacggt
    14821 cataatatta taaatttaga taaatctcaa ttccgtaaac agattggtgt agttactcaa
    14881 caaattcatt tgtttaatcg atctattttt aataacatta cttttcataa tgatacatta
    14941 agtgaacaag aggttatgcg tgcagcagga ttggccgaaa ttcataatga tattatgaat
    15001 ttacctatga agtatcaaac attattgtct gaggaaggta gtaatatatc tggtggtcaa
    15061 agacagcgtt tagctttggc gagagctttg gttcacgacc ctaaaatatt gttactagat
    15121 gaagcaagca gtgccttaga tagtaaaacg gagcagaaaa tttataacaa tattgatagc
    15181 ttaaagtgta caaaaatagt aattgcccat cgattaagta cagttctgcg tgcggataca
    15241 attttagttg tagatcaagg gaaagtgatc gagaggggta cacacgaaca gttaatgaat
    15301 ttaaaaggct cctatgaaaa attatataat gctcaattac agaaagaaaa tatgggggta
    15361 atggtatgag gaaatatata aaatggattc tattaattac gttattttta gttgctggag
    15421 gtggtatatg ggccgtaact aatccaaagg cagcattgga aatgtttgtg gattttggtg
    15481 gtataaatga gggagaagaa atgcctctaa ttacagggga agaagttaat ggtgatacta
    15541 cttctttgga gaaattcaag ggagaaaagt atgttttgat ggtgggtaaa gtggattgtg
    15601 aagtatgtca aaaaacttat ccagttctta aaaatttaaa gaacgagcac ccaaaaacta
    15661 actttattat gataggtcaa ggcgataaaa atgaatacgc tcaaactaag caaaagaatg
    15721 gatttgaatt tcctataata tcagctgatt ccaaaattag tgaagaaatg aatttgaaaa
    15781 tttatcctgt tttttattta gttaatgaaa aaggagaagt tgagaaaaga tcaaatggat
    15841 ttgaagaacc tgagttacaa gagatgctaa gaaaggctga gaaaaattga ataaacgagt
    15901 ccaaattaca ttagttcaaa taatatccat attaggattt ttactttctg tttatttata
    15961 tatatctcat ttgtcaagca gctttttttg tccagttggc gattgtctaa aggttaatag
    16021 tagttcatat gctcaaatta aaggggttcc tatatccaca ctaggtatac tgtattatct
    16081 cctattacat atatttactt actgtggtaa aaaagtattt gtaataaaat taattaaata
    16141 ctggttatta ctaggactag tattctcttt atatttaact tatctggaaa tatttgagat
    16201 taaagcaatt tgtatttggt gtatggtatc ttttggatta attataatag gaagtattat
    16261 cgtctttttt aatagtaaga aagacattgt tgaaaacaaa agatacactt aatggaattt
    16321 ctcttacaat taaagggaat ggaatgtttt gtattatatt agggggaaag gcgaagtctt
    16381 caagtagact tcgttttttt gcgtaaagta aattacagct ggagttagca gtttaatgaa
    16441 atttaattat aaaggcgttt tttgcatgct taagattctt ttccagaaga atttttataa
    16501 ggtgaagcag attagagtga attaagttga gagagcatat ttagaagatt ggataggatt
    16561 taaaagaaac gcctgtaaga ataatatcat taattaggat tagacacttt taagtctttg
    16621 tatctatgaa aaaggataag ttttttatca tttcttcaat tatgtctttt ctagaggggg
    16681 actttgtaca tctttctcgg tttgtctgga tggttgtaca tcaaaaaaca caaaaaaaag
    16741 acactctcaa gagtgcctct tattagcagc cgaatccgcc gccccaacag ctagcgccaa
    16801 cgatgattaa taagataaag agtacaacaa gtaaagcgaa tccgccgccg aaaccacagc
    16861 ctccaccaca actaccgcca tatcccatat taactcctcc ttccataaag accatttaat
    16921 taatggattt aatttacttt atgtttttac ggataaactt gagcaggtcc ttttgaaaaa
    16981 taaaaagtgc ttagatttta aaagagttga cgaacttatt tttgtcacgg gtagtatgct
    17041 aatgacatat tgtattttat tctgtgtatt gggggaagga ggatctttat ggccaattct
    17101 gaaatgattt tacgattact tacggattta aagattgaac agcaagcttt aaaagagcag
    17161 ttggaaaaaa tacaaactgc tgtgactact cttgaagaaa aatcagcgat tgtggaagag
    17221 aaaccaacga ctcttgaaga aaaaccagct gttgctgctg caaagcaaag agctcattct
    17281 ggacacccaa catcttttcg tgcttggaga gcatctgctc aaaggaattc ataaaaatat
    17341 aagaaaagaa gacatctagt aagatgtctt cttttacttg tacaatccaa atgagttaag
    17401 aaggtatatc catattgctt taaaaataag aagaaaataa cgattgtcga ctcctatttt
    17461 agtatagcat gtaataataa agaattttat gtaatgttgc atatatatag attatatgat
    17521 gttaatctta tatattttag ttgtctgtta tttgttttaa ttcatttact tatattattt
    17581 tttgagagcc ccattgatgg ggcctttttt tataattgtt ttaaagcgga aacctctgaa
    17641 gcataatgag gggtttcata actaggtaaa tgattattgg tgcttaatga gatgaagttc
    17701 aggatattgc gtctaaattt cttttaaatg gattaatatt tatttttaaa ccgttcccca
    17761 taaatgataa accataccga taacaaaaaa tgctagtccc acaaacaaaa caattaaagc
    17821 aagcatcccg tttttattat gttccataca gtcagctcct ttttaagtta tatacaaaaa
    17881 gcctttagtc gtaattatgg ctaaaggctt tggtcttcat actttgtagt ttataaaaaa
    17941 gttgcacttc tgtattaatt tggaatatga ttgtttaaag agtaggtgat gagtacatgc
    18001 aggaaacaaa acaattcccg cttatatctg gaaatctctc attagattta gtaaatacag
    18061 agttagttag gcgtggacaa cgttatgatt tattaataac ggatgaagat gtattagaat
    18121 ggctacatgt aataaaggtt aatctgcctt tttggaatga aaaaacactt ataggaattc
    18181 aagagcgcat gaatcaagtt acatctagca tattagaggc aagagaagta ttgcgaaaac
    18241 agtttgaggc aattgccgat cggcacgaaa tttctaatga ttttattacg tatttagaaa
    18301 aacaaattga gaaggcacca tttacatata aagtcattga acagtgtcta gtttctatcc
    18361 cagttggaga aattgaggat gtactcgcat cgttaattgc atttgatgct ttaacgttaa
    18421 tagcagaaaa taagcttatt ttccttaaaa ggtgttcaaa ccctgactgt gttttattat
    18481 ttatagataa aagtggaaag agaaaatggt gttctatgaa aatatgtggg aaccggaaaa
    18541 aggtagcaaa atttcaggtt cgaaagtctg aagaagttta gggaatcaac ttataacagt
    18601 tgattctttt tttctgcatc ttcaaactaa cctctaaact taatattgac tggttagttt
    18661 gtttggaata taattattgg taaataaagg aggagaatga tgagtaatat aacagcagct
    18721 aagcagaaag aggctccacc aataagtgta cgatattttg caaaaatgaa agggaaagga
    18781 agaactccat tacaagtaaa tataaaggac tctttgacag gactattagg gggattttta
    18841 acaattctca ccttaacata tttaacgagt ataacgtcta cagaattgtt aatggctcca
    18901 tttggggcga gttgtgtatt agcgtttgga gtttggaatg caccgttatc tcagccacgt
    18961 aatattattg gaggacattt gatttcaact ttcattggtt tatcaatata tcatttgttt
    19021 gggaatgaat attggacaat tgctttagca gtggggatgt cgattgctat tatgatgtta
    19081 acaagaacaa cgcatcctcc ggcaggggct gatccaattg tcgttatttt aggagcatac
    19141 agttggagtt atttagtaac accagttcta gttggttctc ttgttattgt agcttttgct
    19201 ttattcatta ataatatgag tagtaaaaga agttatccaa ctttttggat ataatttgta
    19261 aagtgaaaaa caatttgagt aattatgccg tttttactat gttttaattt ttatatagaa
    19321 aaaagccttt agtcgtaatg atgaccaaag gcttttattc tcatactttt tagtttacaa
    19381 agaaaagaca cccatataag agtgtctttt ccgatagttt gtttagcaga agcaagaagc
    19441 tccaacgatg attaataaaa taaacaatac aactaatagt gcaaatcctc cagaaaaacc
    19501 gcagcttccg ccgcaactac caccaaatcc cataatagtt cctcctttaa taagagggga
    19561 aaacaaaggg tcactcgtgt tttttaacgg attctattta ctttatgttt tgacgcataa
    19621 acgtgagcag gtccttttga aaataaaaaa agacacctta agatgccttt atcccgcttt
    19681 aatgggcagt aagaccccac ctcaaaattc agcgaaagca aagaatttag gtgggggtcg
    19741 ggctgcccat aaaagtccga ttnnaagttt cactttatgt aattaatatt cgctagcata
    19801 aaactctttt attagcttta tttcatttgt atctgggtta aatttaaata ttttaatttg
    19861 attcgattcg tctttatagg caaatgtatt atcgccaact ggggtcatat tgctggtgtt
    19921 tacgataggg tcactaccat ggtcagtaat ttctacaggt ttctcacgat cccaaaatgc
    19981 aatgacaatg atcaagatga taaggcatat acgtatgtta cgtagttctc tcgatacaat
    20041 attctccatt cgatattctc ctttgttgtt taatagattt tgtttataaa agagataatt
    20101 cttatgaaaa taaataaaaa agacacttga aagtgtcttt tttatttgag ttatgcgcat
    20161 tgcttaataa gacgctagtt cctcaatcgg aatatgagta actatgtagg gtaatttcat
    20221 tataatattt taaccagtaa tgggtctata tggaattttt gtaatgatta tgtttattta
    20281 ttcagaatga tagatgtatc attctgaatt tgatctatta aaagcagtgg aaaaggcaaa
    20341 gggcatactt tattccgtat tataggaatg tatagagata gatttccctt tacacaaaca
    20401 taacggtata atatagttaa gttaagtgaa cttaactatt aaaaatgaaa taacagcatg
    20461 gaggaagaat gctatgacta gaacgtataa agaagtaatt aatgaaatga atcgagccta
    20521 cacggaactc tacattttac tatttcagga tttaaaggat gagttcggtc ttactgggca
    20581 gcaagagagc atgctatttc atattaattt aaatgaaaac acgacagcaa atcacattgc
    20641 gactactttt aatatatcga aaagtgctgt cagccaagtt ttatcgaagt tggaaaagca
    20701 gaagatgatt tcgaaacaag ttaatcctaa caataaaagg gagtatttcc ttacactcgg
    20761 accaaacggt agtaaatata tcgaacgatt gtctgagtta gatgatgtat taattgagaa
    20821 atacttttct aaaatcgata taaatgcttt agagcaaatg actgatacgt taacgaaaat
    20881 aaataaagtg atattggaag agaaacagaa ggctcttgat tgtaatgagt aaaaaggagg
    20941 ggaagcatgt gatgagttac ataccaaata tgattacgat agcaaacttt gtgtgtgggc
    21001 ttttggctat tcacgctgtt ttcgttcacg atatgtatgg tgcagttatg ttcattatta
    21061 caggtatggt atttgatctt tttgatggca tggttgctcg gaaactagat tctgtttcgg
    21121 aaataggcgg agaactagat tcatttgcgg atttagtgac ctttggtgtg gcaccgtcta
    21181 ttcttgcata tagtgcctcg ttaaaagatt tgcagtctat cgggatgtta tgtgcgcttg
    21241 tttatagtat ttgcggaatg cttcggcttg cgagatttaa cacgcagcaa agtaaactcc
    21301 caacctttat cggcatgccc attccattcg cggcaatgtg tcttcttatt ttatgcctcc
    21361 taaataaccc agtttccgtg gaatttggca catgcgtacg cgcttattta atggtgagca
    21421 aaatcaaatt cccccatttt aaaaaggata tatcggaaag cttgaagtcc gaaagatggg
    21481 attaatagga aagataagga gaataacatg attcgtatgg cattaagatc attcaacata
    21541 caaatatatt gtttgctagg cgtgatgtta ttgggatggt tgatgacacc ttttcgagcc
    21601 cagtttgtag ggataagcat tggcctttta gtaagtatgt actgcgcctg gattttagga
    21661 aggcgtatcg aaaagttcgg agatagtatc gtaaaaaaag aaaaagcacc aatgcttggt
    21721 atgatgaatc ggtttgcagc cgcaatactc ggagcgatta ttatgtatga aattgaacac
    21781 catgaattca tgtggacatt tgcagctgga attatggctg ggtatttctt aattattatt
    21841 aatttgggtt attatagtat gagagatgcg aaggaataaa gagctgtgta aataactaat
    21901 ttggatgtaa aagcttaaaa accttccttt atagaaagct ttttattaca aagaaaagac
    21961 acccatataa gagtgtcttt ttcgatagtt ttttagcaga agcaagaagc tccaacaatg
    22021 atcaataaaa taaacaatac aactagtaaa gcaaagccgc cgccacaatt actactacaa
    22081 ctaccaccaa atcccataat agttcctcct ttaataagag gggaaaacaa ggggtcactc
    22141 atgtatttta atggattcaa cttactttat gttttttaca caataattga gcaggtcctt
    22201 ttgaaaataa agaaaagaca ccctaaggtg cctttctccg acttgaacca tcttaatttt
    22261 aataatattg gactcccgtc cgaatattat tttaccatgt taagttgttt ttggaaatat
    22321 tccatatcga taattacagt acacgtttta gtttttgaat tatgtatctg tctaaacgtt
    22381 gaaattaata aaggaacgat atacttgagg gcttttatga gtgattacaa tcatactatt
    22441 aaaaagaacc ccataaatga taaaccatgc cactaacaaa aaacactaat cctaaaaaca
    22501 aaacaattaa agcaagtact ccattttgat tatgttccat aaaattagct ccttttagaa
    22561 ttatttttat cccgctttaa nntaaagttt cactttatat acaaaaaagc ctttagtcgt
    22621 aattatggct aaaggctttg aacattatac tttttagtta ataaaatcgt ataagaagaa
    22681 tttataatgt tttttatcga atgtggaact gacaatgtac tagcttgata atgaagcctg
    22741 gctattagaa ttgaaaaatt ttagttttat tataattaat agaaatgaga gtagtgtgaa
    22801 tataaatccg ctccaaataa gttggtgaat acctaagttt gaaatgaacc agcctccaat
    22861 agtggttcct aaagtaattc cgagatttga gaacgaaacg aatagactgt taccaaattc
    22921 aggtgcttct ttagcttcac ttattaacca tgtttgacca acaattaatc caccagcatg
    22981 tacgattccc caaatgaata ctataaaaat cattggaaca aggtaggaac ctaaataata
    23041 aaccattatg taaacaatag aatatagaat agggaatgat attacagtgt ttattatgct
    23101 tttttgcagg agaccaccaa ataaatgatt acctaaaatc ataactatac caaatatgaa
    23161 tagcatgata ctgatgagag atccattcat ggaagttact tttgcaaggt actcag
//
