LOCUS       NZ_NUEG01000030        25239 bp    DNA     linear   CON 30-JUL-2024
DEFINITION  Bacillus wiedmannii strain AFS005864
            AFS005864_61_A10_Contig15_140312, whole genome shotgun sequence.
ACCESSION   NZ_NUEG01000030
VERSION     NZ_NUEG01000030.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus wiedmannii
  ORGANISM  Bacillus wiedmannii
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 131998)
  AUTHORS   Bleich,R.M., Kirk,G.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Large-scale bioinformatics analysis of Bacillus genomes uncovers
            conserved roles of natural products in bacterial physiology
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 131998)
  AUTHORS   Bleich,R.M., Kirk,G.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Direct Submission
  JOURNAL   Submitted (07-SEP-2017) Chemical Biology and Medicinal Chemistry,
            UNC Chapel Hill, 125 Mason Farm Rd., Chapel Hill, NC 17599, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Assembly Cell v. 4.2.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 37.62x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002555855.1-RS_2024_07_30
            Annotation Date                   :: 07/30/2024 04:09:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,628
            CDSs (total)                      :: 5,554
            Genes (coding)                    :: 5,373
            CDSs (with protein)               :: 5,373
            Genes (RNA)                       :: 74
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 181
            CDSs (without protein)            :: 181
            Pseudo Genes (ambiguous residues) :: 0 of 181
            Pseudo Genes (frameshifted)       :: 56 of 181
            Pseudo Genes (incomplete)         :: 126 of 181
            Pseudo Genes (internal stop)      :: 39 of 181
            Pseudo Genes (multiple problems)  :: 35 of 181
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:21:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 28532
            Orig. end                         :: 53771
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NUEG01000030.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25239
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..25239
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25239
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:15239](-)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15239)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            81..776
                     /locus_tag="CN905_RS18155"
                     /old_locus_tag="CN905_18155"
     CDS             81..776
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) vanR"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038809.1"
                     /locus_tag="CN905_RS18155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18155"
                     /product="response regulator transcription factor"
                     /protein_id="WP_046959467.1"
                     /transl_table=11
                     /translation="MNKNILIIDDDKEIVELLAVYLRNEGYNIYKAYDGDEALQMISTY
                     EVDLMILDIMMPKRNGLEVCQEVRENNTVPILMLSAKAEDMDKILGLMTGADDYMIKPF
                     NPLELVARVKALLRRSSFQNATSSKNEDGIIRIRSAEIHKHNHTVKVNGEYIKLTSIEF
                     DILYLLASNTGRVFSSEEIFERVWNEDGYGSNKTVMVHISNLRDKLETGMNGEKFIHTV
                     WGVGYKIEK"
     gene            766..1923
                     /locus_tag="CN905_RS18160"
                     /old_locus_tag="CN905_18160"
     CDS             766..1923
                     /codon_start=1
                     /gene_functions="resistance (resist) vanS"
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016129473.1"
                     /locus_tag="CN905_RS18160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18160"
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="WP_097890895.1"
                     /transl_table=11
                     /translation="MRNEAFDILKDIPKWKLIFWFMLAITLTPITELIIYRLVTSVIES
                     SLTLSELGKEFIRIFGYEKYKGIKESLWMMIVSYLFLFSIFSSYLYIFYRHEKKIYYET
                     CIKKMIEEIRYIANGNFNHKVSIVNHNYLEELASGVNHIVEQLKVSIDEERQAEQAKSE
                     LITNVSHDLRTPLTSIVGYVNLIHHDNYRDEVELRHYIQVIYDKVTRLNALMNDLFEYT
                     RVQNKELSLYSVPIDIVELLGQLTVQFRIQVQEANIECRPSFPSQKLMVLADGDKLVRV
                     FENLIINAIAYGNDGGYIDLAAYESNNMITIDITNYGQPIPSTDLPHIFERFYRVEKSR
                     STNTGGSGLGLAIAKSIVELHKGTIEVYSDDKKTTFTVKLQPYKC"
     gene            2105..3121
                     /locus_tag="CN905_RS18165"
                     /old_locus_tag="CN905_18165"
     CDS             2105..3121
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160038.1"
                     /locus_tag="CN905_RS18165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18165"
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="WP_087986135.1"
                     /transl_table=11
                     /translation="MQFLKKFTILFLSFVITALIVLYFYLYVNGPIIQAKSAILIDANS
                     GEVVYKKNEEIPIQSATLSKLMTEYIAMEQLNEGNIQLDELVKISNEVFRAETSPIQVT
                     SKDKTTVRDLLHALFLTGNNRSALALAEHIAGNEDNFTLLMNEKSKQLKLSQPSPFLNA
                     TGMNNDTNKQSTTTAIDVAKLATQLVKDFPDVLNVTKLTSYQFTFKDSKVFNTNKMIYS
                     LNKNIKLQGVDGLQTSFSTNGNYSFVSTAKRGDTRLISVILDSNEENSTFIETKKLLQY
                     GFDPSSYSALQAFKDAVTSWTVLLQFKNLIIQTLLIFFIITILMFLHIRQKKSEDFN"
     gene            complement(3180..3638)
                     /locus_tag="CN905_RS18170"
                     /old_locus_tag="CN905_18170"
     CDS             complement(3180..3638)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288270.1"
                     /locus_tag="CN905_RS18170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18170"
                     /product="DinB family protein"
                     /protein_id="WP_048546986.1"
                     /transl_table=11
                     /translation="MYTLFQYNWQVRDDWFKWCEQLSEEELLRKRVGGVGSVLETLFHI
                     VDVEYSWISALQGKEDNEPQFKDYQSIQKVKALSNLYIRELEDFLQLWSSSLECKILKA
                     SWTDKTYTYGEVLRHVIVHEIHHIGQLSIWARELNLQPVSANLIGRGL"
     gene            complement(3645..4385)
                     /locus_tag="CN905_RS18175"
                     /old_locus_tag="CN905_18175"
     CDS             complement(3645..4385)
                     /NRPS_PKS="Domain: Abhydrolase_1 (27-135). E-value:
                     6.2e-15. Score: 47.4. Matches aSDomain:
                     nrpspksdomains_CN905_RS18175_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240893.1"
                     /locus_tag="CN905_RS18175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18175"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_098067836.1"
                     /sec_met_domain="PF00561 (E-value: 1.2e-11, bitscore: 37.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.2e-11, bitscore:
                     36.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKCIEEYLQVDDFKMYTKKFQGKKLQPVIIMEAGYGDYSKTWDH
                     IAEELTEYGTVLTYDRAGLGKSGKSSKRRISSEMVKDLRSCLAQLQLKPPYIFVGHSFG
                     GINARLFATSYPKDLLGIVLVDSTPENYKEDFLPIMSPEFQEAYYKQFVYESSYEEFTF
                     SLSEVDRHCKSMNDIPLVVLAAGKKAFYSPDAQMKWLQLQEELLRLSYNHKFVIAEKSG
                     HYIQKDEPYYVIDAVKWIVEVGER"
     aSDomain        complement(3981..4304)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CN905_RS18175_Abhydrolase_1.1"
                     /evalue="6.20E-15"
                     /label="CN905_RS18175_Abhydrolase_1.1"
                     /locus_tag="CN905_RS18175"
                     /protein_end="135"
                     /protein_start="27"
                     /score="47.4"
                     /tool="antismash"
                     /translation="PVIIMEAGYGDYSKTWDHIAEELTEYGTVLTYDRAGLGKSGKSSK
                     RRISSEMVKDLRSCLAQLQLKPPYIFVGHSFGGINARLFATSYPKDLLGIVLVDSTPEN
                     YKED"
     CDS_motif       complement(4068..4103)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CN905_RS18175_0001"
                     /evalue="5.60E-05"
                     /label="NRPS-te1"
                     /locus_tag="CN905_RS18175"
                     /protein_end="106"
                     /protein_start="94"
                     /score="15.7"
                     /tool="antismash"
                     /translation="PYIFVGHSFGGI"
     gene            complement(4378..4938)
                     /locus_tag="CN905_RS18180"
                     /old_locus_tag="CN905_18180"
     CDS             complement(4378..4938)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001039243.1"
                     /locus_tag="CN905_RS18180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18180"
                     /product="hypothetical protein"
                     /protein_id="WP_098068015.1"
                     /transl_table=11
                     /translation="MNKNTKVISVAAVSGGGKTTVTESLTHKLMNSKALYFDSYDFDNC
                     PADICKWIDDGANYDEWVLTPLIHDIQHLIREANVDYIILDYPFAYLNSEMREFIDVTI
                     FIDTPLDIAMARRILRDFKEDTIDEIHNDLKHYMTFARKAYLEAIHTVKPNSDIILDGS
                     LSVGEIINHAVEELGLRELIVNG"
     gene            complement(4990..5511)
                     /locus_tag="CN905_RS18185"
                     /old_locus_tag="CN905_18185"
     CDS             complement(4990..5511)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003170788.1"
                     /locus_tag="CN905_RS18185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18185"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_098076914.1"
                     /transl_table=11
                     /translation="MRVIKLKQFTRTDFKQLINWIDCEEFLIQWSGNLFTYPLHEQQLE
                     KYIESKNTLAFKVIDEETRKVIGHISLGQIDNINKSARIGKVLVGDTKMRGRSIGKHMM
                     KAVLQIAFKELKLHRVTLGVYDFNTSAISCYEKIGFVKEGLLRESKKVGETYWNLWEMS
                     MLEYEWSDKK"
     gene            complement(5631..5987)
                     /locus_tag="CN905_RS18190"
                     /old_locus_tag="CN905_18190"
     CDS             complement(5631..5987)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002032241.1"
                     /locus_tag="CN905_RS18190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18190"
                     /product="hypothetical protein"
                     /protein_id="WP_000535579.1"
                     /transl_table=11
                     /translation="MGSRFNNCRKKCTCKHDDCWDVFEECKKEQHEKCDSSCVQGIRDE
                     LKKLINKTVRINTEGRTYIGTVSSVTCDVVKLAAIPGSVAAIISLCKIEAILPPATTVA
                     DEFDFNGVDVANKE"
     gene            6544..6774
                     /locus_tag="CN905_RS29080"
     CDS             6544..6774
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CN905_RS29080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_141521022.1"
                     /transl_table=11
                     /translation="MKGGIKECPGKMIAGVLRKSIVVMTGGNLKKRIIVMMIGVLNEIS
                     VVVNVSLFVFIVIEKIGNIFDIDLKERTCLL"
     gene            complement(6878..7258)
                     /locus_tag="CN905_RS18195"
                     /old_locus_tag="CN905_18195"
     CDS             complement(6878..7258)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450238.1"
                     /locus_tag="CN905_RS18195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18195"
                     /product="hypothetical protein"
                     /protein_id="WP_002127497.1"
                     /transl_table=11
                     /translation="METSTFLGLFWGWITVIVSGILFVRPSVLRELKKLVVEDRGFGIM
                     YGFLSIFLGLGSVILHNVWVFNWQGFLTVIAWLALLKGIYIIAYPEPSKKTDFELRVLS
                     TRIALAIIGALALWMLIVIYIK"
     misc_feature    7367..7380
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.54"
                     /tool="antismash"
     misc_feature    complement(7368..7381)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.54"
                     /tool="antismash"
     gene            complement(7425..7592)
                     /locus_tag="CN905_RS29420"
     CDS             complement(7425..7592)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284254.1"
                     /locus_tag="CN905_RS29420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_176523135.1"
                     /transl_table=11
                     /translation="MYQGDYFITEGTILKVSEKANKSLYWLWCMLAPSYEKVCGNSTKR
                     LRLIRIDDEE"
     gene            7922..8290
                     /locus_tag="CN905_RS18200"
                     /old_locus_tag="CN905_18200"
     CDS             7922..8290
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002189674.1"
                     /locus_tag="CN905_RS18200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18200"
                     /product="septum formation initiator family protein"
                     /protein_id="WP_098085567.1"
                     /transl_table=11
                     /translation="MGNIPKISSQQSNPNIPSQQVNANTKQGNNKITRRRIITTLAFIL
                     PIIFVLQYSLNNQQEMIKEKQITVNTEQQKLFSVKKDSHSLKNDVKALTSNEEEILKFA
                     RKLYGFSKPNETIFQITE"
     gene            8488..>8544
                     /locus_tag="CN905_RS29820"
                     /pseudo=""
     CDS             8488..>8544
                     /GO_component="GO:0043592 - exosporium [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03720.3"
                     /locus_tag="CN905_RS29820"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="exosporium leader peptide-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDEFLSFAALNPVSIGPTL"
     gene            complement(8562..8783)
                     /locus_tag="CN905_RS29825"
     CDS             complement(8562..8783)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254010.1"
                     /locus_tag="CN905_RS29825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_240514097.1"
                     /transl_table=11
                     /translation="MVSLEVKVIDAGPAGRLNPVGPVDPVGPVGPVGPVDPVGPVGPVG
                     PVGPVDPVGPVDPVDPVAPVEPVGPVGN"
     misc_feature    complement(8792..8809)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 23.05"
                     /tool="antismash"
     gene            complement(8829..9044)
                     /locus_tag="CN905_RS29830"
     CDS             complement(8829..9044)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237376.1"
                     /locus_tag="CN905_RS29830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_240514096.1"
                     /transl_table=11
                     /translation="MVIMTLAIVPGESRSEAVTVTVPGPLAARNTAVKLPEALVMTARG
                     TMKAREGLLNEKLTTTPGVGLPFTNT"
     gene            9361..9558
                     /locus_tag="CN905_RS18210"
                     /old_locus_tag="CN905_18210"
     CDS             9361..9558
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002017016.1"
                     /locus_tag="CN905_RS18210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18210"
                     /product="hypothetical protein"
                     /protein_id="WP_097917206.1"
                     /transl_table=11
                     /translation="MDKKDLLSQQLEHVSSDALNTPSKAQEQMQEASQQAHVSNKKDST
                     QSLHGEDLPISDVYRTTNKQ"
     gene            complement(10001..11941)
                     /locus_tag="CN905_RS18215"
                     /old_locus_tag="CN905_18215"
     CDS             complement(10001..11941)
                     /NRPS_PKS="Domain: AMP-binding (98-521). E-value: 1.7e-82.
                     Score: 269.1. Matches aSDomain:
                     nrpspksdomains_CN905_RS18215_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017560287.1"
                     /locus_tag="CN905_RS18215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18215"
                     /product="AMP-binding protein"
                     /protein_id="WP_097917208.1"
                     /sec_met_domain="AMP-binding (E-value: 6.7e-90, bitscore:
                     294.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQAVWFPTEEYKEKTRLYGWMKSLGYEDYETFYNKSIEETDWFW
                     GEAEKAVGYQWMKPYTEVLDLENGTPFAQWYNGGTCNVVESVLSRWLADDETRTQPALQ
                     YVGENGTSKSFTYEELDNWVSRVANGLKHAGIEKGDRVTIYMPMIPETVVAMLAVMKIG
                     AIISPIFSGFASDAVMTRVQAAGSKMIITADGFSRRGKVVSLKDEVDKACKHCPTVEKV
                     VIVRHAGNDFTPHNYDFPWSALEKEKPFTHAEEMNSDDPLMLIYTSGTTGKPKGTVHTH
                     AGFPLKSAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLLFGSLINGATMVMYEGVPDFPE
                     ADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHSLKSLEVFASTGEPWNPDPWMW
                     LFETVGKNNVPICNYSGGTEISGGIFGNVLIKPIAPISFNASLPGMAAVVLDDQGNPIR
                     DEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKWVHGDWVIYDGEQYIITGRSDD
                     TLNIAGKRIGPAEYESILVKHNDVIEAAAIGVPDDVKGEVCHCFVVLRDNVTFTGELKK
                     ELMSLVNSHIGKALCPKDIHVVEDLPKTRNSKVMRRVIKAAYLGKELGDLSSLVNPEVV
                     PFIQGLQSSKL"
     CDS_motif       complement(10346..10408)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CN905_RS18215_0002"
                     /evalue="7.80E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="CN905_RS18215"
                     /protein_end="532"
                     /protein_start="511"
                     /score="12.3"
                     /tool="antismash"
                     /translation="TGRSDDTLNIAGKRIGPAEYE"
     aSDomain        complement(10379..11647)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CN905_RS18215_AMP-binding.1"
                     /evalue="1.70E-82"
                     /label="CN905_RS18215_AMP-binding.1"
                     /locus_tag="CN905_RS18215"
                     /protein_end="521"
                     /protein_start="98"
                     /score="269.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="TQPALQYVGENGTSKSFTYEELDNWVSRVANGLKHAGIEKGDRVT
                     IYMPMIPETVVAMLAVMKIGAIISPIFSGFASDAVMTRVQAAGSKMIITADGFSRRGKV
                     VSLKDEVDKACKHCPTVEKVVIVRHAGNDFTPHNYDFPWSALEKEKPFTHAEEMNSDDP
                     LMLIYTSGTTGKPKGTVHTHAGFPLKSAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLLF
                     GSLINGATMVMYEGVPDFPEADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHSL
                     KSLEVFASTGEPWNPDPWMWLFETVGKNNVPICNYSGGTEISGGIFGNVLIKPIAPISF
                     NASLPGMAAVVLDDQGNPIRDEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKWV
                     HGDWVIYDGEQYIITGRSDDTLNI"
     CDS_motif       complement(11099..11155)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CN905_RS18215_0001"
                     /evalue="7.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="CN905_RS18215"
                     /protein_end="281"
                     /protein_start="262"
                     /score="24.7"
                     /tool="antismash"
                     /translation="MLIYTSGTTGKPKGTVHTH"
     gene            complement(11991..13532)
                     /locus_tag="CN905_RS18220"
                     /old_locus_tag="CN905_18220"
     CDS             complement(11991..13532)
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389703.2"
                     /locus_tag="CN905_RS18220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18220"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_097917210.1"
                     /transl_table=11
                     /translation="MLDQKQQSNTFEERVEAIKQGGAPKYHEQNKAKGKLFVRDRLALL
                     FDNGEYVEDALFANCEQTGLPADGVITATGKIHGRTACVMANDSTVKAGSWGARTVEKI
                     LRIQETAEKLRVPLFYLVDSAGARITDQVEMFPGRRGAGRIFYNQVKLSGKVPQVCLLF
                     GPSAAGGAYIPAFCDIVMMVEGNASMYLGSPRMAEMVIGEKVTLEEMGGARMHCSVSGC
                     GDVLCKTEEDAITQARQYISYFPNNYLEKTPLVTPQEPKQFEKTLEQIIPENQNAPFNM
                     KDLINRIIDEGSFYEVKKLFAQELITGLARIDGKPVGIIANQPRMKGGVLFHDSADKAA
                     KFINLCDAYHIPLLFLADVPGFMIGTKVERAGIIRHGAKMISAMSEATVPKISIVVRKA
                     YGAGLYAMAGPAFEPDCCLALPTASIAVMGPEAAVNAVYANKIAALPEEERDSFIAEKR
                     EEYKKDIDIYHLASEMVIDGIVHPNNLREELKGRFEMYMSKYQVFTDRKHPVYPV"
     gene            complement(13535..14323)
                     /locus_tag="CN905_RS18225"
                     /old_locus_tag="CN905_18225"
     CDS             complement(13535..14323)
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (14-254). E-value: 4.3e-74. Score:
                     240.8. Matches aSDomain:
                     nrpspksdomains_CN905_RS18225_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001990763.1"
                     /locus_tag="CN905_RS18225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18225"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_087980476.1"
                     /transl_table=11
                     /translation="MLQLQNISVNYVTPHVIKISLYRERQANSLSLALLEELQNILTQI
                     SEESNTRVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSMIRTTMEMVEQLPQPVIA
                     AINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKEL
                     IYTGRRISAQEAKEYGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQV
                     DLHTGLQMEKQAYEGVIHTKDRLEGLQAFKEKRTPMYKGE"
     aSDomain        complement(13562..14281)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CN905_RS18225_ECH.1"
                     /evalue="4.30E-74"
                     /label="CN905_RS18225_ECH.1"
                     /locus_tag="CN905_RS18225"
                     /protein_end="254"
                     /protein_start="14"
                     /score="240.8"
                     /tool="antismash"
                     /translation="HVIKISLYRERQANSLSLALLEELQNILTQISEESNTRVVILTGA
                     GEKAFCAGADLKERAGMNEEQVRHAVSMIRTTMEMVEQLPQPVIAAINGIALGGGTELS
                     LACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKE
                     YGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYE
                     GVIHTKDRLEGLQAFKEK"
     gene            complement(14328..15239)
                     /gene="mvaB"
                     /locus_tag="CN905_RS18230"
                     /old_locus_tag="CN905_18230"
     CDS             complement(14328..15239)
                     /EC_number="4.1.3.4"
                     /codon_start=1
                     /gene="mvaB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017149491.1"
                     /locus_tag="CN905_RS18230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18230"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_046955915.1"
                     /sec_met_domain="HMGL-like (E-value: 4.4e-49, bitscore:
                     160.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPNFAVIKEVGPRDGLQNEKKIVGTKDKVKWIQLLTEAGLSYV
                     EVSSFVHPKWVPALADANDVFSELKRDPNVTYAALVPNQNGLERAFLQNVDEVNVFLSA
                     SESHNKSNINKSIKEALVVIEDITKQAIFEGKKVRGYVSTVFGCPYEGDISATAVDELC
                     NQLFSYGIYEVSLGDTIGVANPLQVERVLEHLLKKYDASQFAMHFHNTYGMALANVVKS
                     LEYGITTFDSSCGGLGGCPYAPGASGNVATDDLVHMLHKLGVQTNIDEEKLLKASQFIQ
                     SKLNIQLPSHVYRALQHKTISR"
     gene            complement(15261..15476)
                     /locus_tag="CN905_RS18235"
                     /old_locus_tag="CN905_18235"
     CDS             complement(15261..15476)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001987345.1"
                     /locus_tag="CN905_RS18235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18235"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="WP_001987345.1"
                     /transl_table=11
                     /translation="MMTKVYASMAGNVWKIVVGVGDTVEEEQDVVILESMKMEIPIISE
                     EAGTVMKINVQEGDFVNEGDVLLEIE"
     gene            complement(15503..16840)
                     /locus_tag="CN905_RS18240"
                     /old_locus_tag="CN905_18240"
     CDS             complement(15503..16840)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000486723.1"
                     /locus_tag="CN905_RS18240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18240"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_000486754.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 4.9e-12,
                     bitscore: 38.4, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 6.6e-08, bitscore:
                     25.4, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 5.4e-08, bitscore: 25.3,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 8.7e-11, bitscore:
                     34.3, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQKILIANRGEIAVRIMKTCQKLGIRTVAIYSEADENALHVKMA
                     NEAYLVGGPRVQESYLNLEKIIEIAKKTNAEAIHPGYGLLSENPSFPVRCREEGIVFIG
                     PSEEIITKMGSKIESRIAMQAADVPVVPGITTNIETAEEAIEIAKQIGYPLMLKASAGG
                     GGIGMQLMETEQTLTKAFESNKTRAQNFFGNGEMYLERYIADAHHIEIQLLADTHGNTV
                     YLWERECSVQRRNQKVIEEAPSPFLDEGTRKAMGEVAVQAAKALGYTNAGTVEFLVDDQ
                     KNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLLIAYGEKLSFTQDDVKRSGHAIEARIY
                     AEDPKTFFPSPGKITDLTLPSNVRIDHFLENQVTITPFYDPMIAKVIAHGETREEAISK
                     LHDALEELKVEGIKTNTPMLLQVLEDDVFKSGIYTTGFVTKQLVKK"
     gene            complement(16856..18001)
                     /locus_tag="CN905_RS18245"
                     /old_locus_tag="CN905_18245"
     CDS             complement(16856..18001)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001980414.1"
                     /locus_tag="CN905_RS18245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18245"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_076537766.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2e-41, bitscore:
                     133.9, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1e-27, bitscore:
                     88.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 8.8e-58, bitscore:
                     187.5, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFTLTREKQMIKEMVRDFAEKEIAPKAVYYDKTGEFPYETFQKM
                     GELGLLGIPFPEEYGGSGGDTVSYALAVEEIGRACGGTGLSYAATISLGASPIYYFGTE
                     EQKQKYLVPMASGKTLGAFGLTEPNAGSDAGGTQTKAVLDGDEYVISGEKCWITNAEYA
                     NTIIVTAINGVEDNGRKRISAFIVPTTSEGLTISSPYDKMGVRASNTCEIVLDGVRVPK
                     ENILGDVNKGFKQFLYTLDGGRISIAALAVGIAQSAFERALQYAKERQQFGKSISNFQA
                     IQFKLADMATEVELARNLVHKAAWLKDNDKPFGKEAAMAKLFASEAASRIANQSVQIHG
                     GYGYMREYEVERHIRDAKLLEIGEGTSEIQRLVIARHLGCR"
     gene            complement(18218..19186)
                     /locus_tag="CN905_RS18250"
                     /old_locus_tag="CN905_18250"
     CDS             complement(18218..19186)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248633.1"
                     /locus_tag="CN905_RS18250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18250"
                     /product="DUF523 and DUF1722 domain-containing protein"
                     /protein_id="WP_097917212.1"
                     /transl_table=11
                     /translation="MRQFAKPTIVVSKCLEFDACRYNAEMIPDVTIRNLQPFVTFIPVC
                     PEVEIGLGTPRETIRIVEENGVNRLVQPSTREDVTEKMEQFSYVFLQTISDVDGFILKN
                     RSPSCGTRDVKIYSGFEKAPAKGKGSGLFGGAVIKKFSHLPIEEEGRLSNFIIREHFFT
                     RLFTIAYYKMIKHNKNMKDLVSFQSDNKYLFMAYNQVKQKELGRIIANQKNEKIEIVFD
                     KYEKTLYELFMRTPRYTSNVNVCEHIFGYFKTKLKKQEKDHFLDLIQKYKEKKIPLSSL
                     LTILKSWAIRFDDKYLLRQTYFEPYPEALVEISDSGKGRDY"
     misc_feature    complement(19273..19286)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.68"
                     /tool="antismash"
     misc_feature    19358..19373
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 24.07"
                     /tool="antismash"
     gene            19652..20167
                     /locus_tag="CN905_RS18255"
                     /old_locus_tag="CN905_18255"
     CDS             19652..20167
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512145.1"
                     /locus_tag="CN905_RS18255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18255"
                     /product="DUF3231 family protein"
                     /protein_id="WP_000538613.1"
                     /transl_table=11
                     /translation="MGVLSGNPQNEPMHYGEVFAIWSYLAGAQGAIAGYQVLVNHTGDE
                     DLKKFLENLIENDIQSEVEELKNLLKSNGVALPPAPPERPVASIETIPPGARINDAEIA
                     AKVSMDLAAGLVACSQAMGQSLREDVGMMFGQFHMKKAQAGATLLRLNKKKGWIIPPPL
                     HVLQSDQA"
     gene            20340..20639
                     /locus_tag="CN905_RS18260"
                     /old_locus_tag="CN905_18260"
     CDS             20340..20639
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728146.1"
                     /locus_tag="CN905_RS18260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18260"
                     /product="WGxxGxxG family protein"
                     /protein_id="WP_063224864.1"
                     /transl_table=11
                     /translation="MKKKLSSILSVLALSIMFLGTSAQAEYDGNNMNRVNNTDISTRVN
                     DNNLDRVNNDVRTRNVNTTNDLNDNRDKNNNWAWLGLLGLAGLLGLRRRDKETR"
     gene            complement(20763..21416)
                     /locus_tag="CN905_RS18270"
                     /old_locus_tag="CN905_18270"
     CDS             complement(20763..21416)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168192.1"
                     /locus_tag="CN905_RS18270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18270"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_097917214.1"
                     /transl_table=11
                     /translation="MKKDWLDELIAATNTDKRNERQMRILEAAVDMFGEKGYASTSTSE
                     IAKRAGVAEGTIFRYYKTKKDLLLAVVMPTLTKFAAPFFVQAFAKEIFKSEYESYEGLL
                     RVVIHNRFEFAKKHFPMIKILIQEVPFQRELKNEIQHLVETELLSHFKKLIVKFQEEGE
                     IIEMPPSSVLRLTLSAVLGLLLTRFLLLPEEKWDDEVEIENTIQFILYGLTPRI"
     gene            complement(21441..22460)
                     /locus_tag="CN905_RS18275"
                     /old_locus_tag="CN905_18275"
     CDS             complement(21441..22460)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002161721.1"
                     /locus_tag="CN905_RS18275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18275"
                     /product="ABC transporter permease"
                     /protein_id="WP_097917216.1"
                     /transl_table=11
                     /translation="MRVTGVIIRIIRQFFRDKRSLAMMFGAPMLLLWLLSLVFTQKDYV
                     PHIAVVDLPAPIVKTMKTQEASIYEYGKEKAISELEQQKVDAVIYLENGKMNLLLEGSD
                     SSKNRAVLQVLQKSSEKNDVSVMKPEVNYLHGSKDFTMFDGLGPVLIGFFTFFFVFILS
                     GVSFVRERLSGTLERLLSTPVRRWEIVVGYIIGFGIFAFIQSIIIVNFSVYILDLYVAG
                     SIWLTLLITCMLSLTALTLGTFLSAYANNEFQMIQFIPLVIVPQIFFSGLFPIESMNKW
                     LQMLGKLFPLTYGADAMRQVMIRNQGFTEIALNLTVLLLFSLLFAIGNVFALKKHRKI"
     gene            complement(22457..23182)
                     /locus_tag="CN905_RS18280"
                     /old_locus_tag="CN905_18280"
     CDS             complement(22457..23182)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016087811.1"
                     /locus_tag="CN905_RS18280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18280"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_046959450.1"
                     /transl_table=11
                     /translation="MQQPSIILRTVSKSFGKKEVLHNLSLQVEKAEIFGLVGPSGSGKT
                     TLIKLIAGINEASEGEVLVYNTNMPNLNEMKRIGYMAQADALYEELSAYENADFIATMY
                     GLKGKHKKERIEEVFDLVQLSQHIRQQVQHFSGGMKKRLSLAIALLHEPEILILDEPTV
                     GIDPLLRKTIWEKFYDLKKKGTTIIVTTHIMDEAEFCERLGLIREGKLVATGTPEELKK
                     RVSSGRIEDVFLLEEVALS"
     gene            complement(23362..23613)
                     /locus_tag="CN905_RS18285"
                     /old_locus_tag="CN905_18285"
     CDS             complement(23362..23613)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548597.1"
                     /locus_tag="CN905_RS18285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18285"
                     /product="hypothetical protein"
                     /protein_id="WP_000548621.1"
                     /transl_table=11
                     /translation="MHKEYEIEEYTAIEEQIHYYCKCLLVSHPDQIIKYLEKRLEKYAE
                     TLQYAHLYPDTVILPLQQLVIEYSLDVARIRKYMNLKT"
     gene            complement(23822..24664)
                     /locus_tag="CN905_RS18290"
                     /old_locus_tag="CN905_18290"
     CDS             complement(23822..24664)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002141840.1"
                     /locus_tag="CN905_RS18290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN905_18290"
                     /product="metallophosphoesterase"
                     /protein_id="WP_097917218.1"
                     /sec_met_domain="Metallophos_2 (E-value: 6.8e-11, bitscore:
                     35.2, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKAKRIILLIATLVGFSIFLYVQNNLISITEVKITSNKIPSSF
                     KGFKILQISDLHNKKFGDNQETLIQKVKSINPDIIAITGDLIDSKSYDPEVSMELIRKL
                     VKKYPVYFVTGNHEKWSGKYNNLEKELKKHHVIVLRNEHVTIQKGEQKINLLGIDDPEF
                     VTGNRDEGNVVKDEIIKAKIETQPDTYNVLLSHRPEFLTEYADEQIDLVLSGHAHGGQV
                     RLPFIGGLVAPNQGMFPTYTAGLYEKQNTSMVVSRGLGNSIIPQRIFNRPELVVVQLN"
ORIGIN
        1 atggcgattc attgctacaa aatacataaa tttttgatat tatagtaatg ttaatgattt
       61 gttaggaaag gaactacata atgaataaaa acatattaat tattgatgat gataaagaaa
      121 ttgttgagtt acttgctgtt tatttgcgaa atgaaggcta taacatttat aaagcatacg
      181 atggtgatga agcattgcaa atgatttcta catatgaagt tgaccttatg attttggata
      241 ttatgatgcc aaaacgaaac ggattagaag tttgccaaga ggttcgtgag aataatactg
      301 tacctattct tatgttgagt gcaaaggcag aagatatgga taaaatatta ggtcttatga
      361 caggtgcaga tgattatatg attaagccct tcaatccatt agaattagta gctagagtga
      421 aagctttgtt acgaagatca tctttccaaa atgccacttc ctccaaaaat gaagatggta
      481 ttattcgtat tcgttctgct gaaatacaca aacataatca tacagttaaa gtcaatggag
      541 aatacattaa acttacatcc attgaatttg atattttata tttacttgcg agtaatacgg
      601 gaagagtatt tagttccgaa gaaatttttg aacgcgtttg gaatgaagat ggttatggtt
      661 caaataaaac tgtaatggtt cacattagta atttacggga taaacttgaa acaggaatga
      721 atggagagaa gtttattcat actgtttggg gagtaggcta taaaattgag aaatgaagca
      781 tttgatatat taaaagatat cccaaagtgg aagttaattt tttggttcat gttagctatc
      841 acacttaccc ctattactga attaattata tatcgtctcg ttacaagtgt aattgaaagt
      901 tcacttacgt taagcgagct cggaaaagaa ttcattagaa tttttggata tgaaaaatat
      961 aaaggaataa aggaatctct atggatgatg attgtatctt atttgttttt attttctatt
     1021 ttctcatctt acctatacat tttttatcgt catgaaaaaa agatttatta tgaaacttgt
     1081 attaaaaaaa tgatagaaga gattcgttat attgcaaatg gaaacttcaa tcataaagtt
     1141 tctatcgtaa atcataatta tctggaagag ttagcaagcg gggttaatca cattgttgaa
     1201 caattgaaag tctcaataga tgaagagaga caggcagaac aagcaaaaag tgaacttatt
     1261 acaaatgtat cgcatgattt acgtactcct cttacctcta tagttggata cgtaaattta
     1321 atccaccatg ataattatag agatgaagtc gaattacgcc attatataca agtcatttac
     1381 gataaagtaa cccgtcttaa cgcattaatg aatgatttgt ttgaatatac acgtgttcaa
     1441 aataaagagt taagtttata ttctgttccc attgatattg tagagctact tgggcaatta
     1501 actgttcaat tccgcataca agttcaagaa gctaatatag aatgtcgacc ttctttccca
     1561 tctcaaaaac tcatggtatt agctgatgga gacaaattag tacgagtgtt tgaaaatctt
     1621 attataaatg ctatcgctta tggaaacgac ggtggatata tcgaccttgc tgcctatgaa
     1681 agcaataata tgattactat agatataaca aattacggcc aacctattcc tagtacggat
     1741 ttacctcata tttttgaacg tttttatcgc gttgaaaaat ctcgctctac gaacactggt
     1801 ggatctggac tcggattggc aattgcaaaa agtattgtgg aattgcataa aggaacaatt
     1861 gaagtatata gtgatgataa aaaaacaact ttcactgtaa aactacaacc atataaatgt
     1921 taatacaact taattttagg tccaatttct taccatataa gaaattggac cttttatttt
     1981 ccattaaaat ccagaattta ataatccttt ataattcttt agaaattctt taccttttct
     2041 ttcttcctaa ttaagcattc ctttttacaa tagtattatt gatgtcatag taggaggatc
     2101 gcttatgcaa ttcttgaaaa agttcacaat tttattctta tcttttgtta ttacagcact
     2161 tatcgtttta tatttttatc tttatgtaaa tggtccaatt attcaagcta aatcagctat
     2221 tttaatagat gctaattcag gtgaagttgt ttataaaaaa aatgaagaaa ttcctataca
     2281 gtctgctact ttatctaaat taatgacaga gtatatcgca atggaacaac tgaatgaagg
     2341 aaacatacag ttagatgaat tagtaaaaat aagtaacgaa gtcttcagag cagaaacgag
     2401 tcctatacaa gtaacttcga aagataaaac gacagttcgt gatttacttc atgcattgtt
     2461 tttgacaggg aataatcgtt ccgcacttgc ccttgcagaa cacattgctg gaaacgaaga
     2521 taactttaca cttttaatga atgagaaatc aaaacaacta aagttatcac aaccatcccc
     2581 gtttctaaat gctactggaa tgaataacga tacaaataaa caatcaacta caacagctat
     2641 agacgtagct aaactagcga cacaattagt aaaagacttt ccagatgtat tgaatgttac
     2701 gaaactaacc tcttaccaat ttaccttcaa agactcaaaa gttttcaaca caaataaaat
     2761 gatttattct cttaataaaa acattaaact ccaaggtgtt gacggcttac aaactagttt
     2821 ttcaactaat ggtaattata gttttgtcag tacagcaaaa cgaggagata ctagacttat
     2881 ttccgtaata ttagactcca atgaagaaaa tagtactttt attgaaacaa aaaagttact
     2941 acagtacggt tttgatcctt cctcgtactc tgcactccaa gcttttaaag atgctgttac
     3001 atcgtggaca gttttgcttc aatttaaaaa tttgatcata caaacattgt tgattttctt
     3061 catcattaca attttaatgt ttttacatat acgtcagaaa aaatccgagg atttcaacta
     3121 ggaaatcttc ttttatataa aaaccggctt gcatttacag tgcaagccgg tttctaaatt
     3181 tataatcctc ttccaattaa attcgctgaa acaggctgaa gatttaattc tctcgcccat
     3241 atagatagct gaccaatatg gtgaatttca tgcacaatta catgtcttaa aacttcaccg
     3301 tatgtatatg ttttatctgt ccacgaagct tttaatatct tacattctag gctagatgac
     3361 cacaactgta aaaaatcttc taattctcgt atatataaat tagataacgc tttcactttt
     3421 tggatggatt gataatcttt aaactgcggt tcattatctt cttttccttg aagcgcacta
     3481 atccagctgt actcaacatc gacaatatgg aataatgttt ctaaaacact cccaacacca
     3541 cctacacgct tgcggagtaa ttcttcctct gaaagttgtt cacaccactt aaaccaatca
     3601 tcccttactt gccaattgta ttgaaataac gtgtacatat atatttatct ctcccctacc
     3661 tcaacaatcc acttaaccgc atctattaca taatatggtt catctttttg aatatagtga
     3721 ccgctttttt ctgcaattac aaatttatga ttgtatgata atcgtaataa ttcttcttgc
     3781 aattgtaacc atttcatttg tgcatctggc gaataaaaag cttttttacc cgcagctaac
     3841 acgacaagtg gaatatcatt cattgattta caatgtctat ctacttcact taaactaaat
     3901 gtaaactctt cataagaact ttcatataca aactgtttat agtaagcttc ttgaaattct
     3961 ggagacatga ttggcagaaa atcttcttta taattttccg gtgtcgaatc aaccaaaacg
     4021 attcccagca aatctttggg ataagaagtc gcaaataaac gtgcatttat accgccaaaa
     4081 gaatgtccta caaaaatata aggtggtttc aattgtagtt gcgctaagca acttcttaaa
     4141 tcttttacca tttcagaact aatacgtcgc ttggaactct tcccactttt tcctaagccc
     4201 gctcgatcat atgtaagtac cgtcccatat tccgtcaact cttcagcgat atgatcccat
     4261 gtctttgaat aatcaccata acctgcctcc attataataa ctggctgcag cttctttcct
     4321 tggaactttt tcgtatacat tttaaaatcg tcaacttgta aatattcttc tatacattta
     4381 accattgaca atcaattctc tcaggccaag ttcctctaca gcatgattaa ttatttcacc
     4441 tacagataaa gagccatcca atataatatc cgaattcggc ttaacagtat gaattgcctc
     4501 taaatatgct tttctcgcaa atgtcatgta atgtttcaaa tcattatgta tttcatctat
     4561 tgtatcttct ttaaaatctc gcaaaattct tctagccatc gcaatatcta aaggtgtatc
     4621 gataaatata gttacatcaa taaattctcg catttcacta tttaggtatg caaaaggata
     4681 atctaaaata atataatcta cattagcctc tcgtataaga tgctgaatat catgaattaa
     4741 tggcgtaagt acccattcat cataatttgc tccatcatca atccatttac aaatatcagc
     4801 aggacaatta tcaaagtcat agctatcaaa atatagtgct tttgaattca ttaacttgtg
     4861 agttaaactt tctgtaacag tagttttacc tcctcctgaa acagctgcaa ctgaaattac
     4921 tttagtattt ttattcataa cttcccacca tacccctttt aattgacata acataattat
     4981 aaaaaactat tattttttat cactccattc atattctaac atactcattt cccataaatt
     5041 ccaatatgtt tctcctactt ttttggattc tcttaataaa ccttctttta caaatcctat
     5101 tttttcataa catgagatgg ccgacgtatt aaaatcataa acaccaagag ttactctatg
     5161 tagttttaat tctttaaatg caatttgtaa tactgctttc atcatatgtt tccctataga
     5221 acgccctcgc attttcgtat caccaactaa cacttttcca attcttgcag atttatttat
     5281 attgtcaatt tgcccaagtg aaatatgacc aattactttt ctagtctctt catctattac
     5341 tttaaatgca agcgtatttt tgctttcaat atatttttct aattgttgtt catgtaaagg
     5401 gtatgtaaat aaatttcctg accactgtat taaaaattct tcgcaatcaa tccaatttat
     5461 taattgtttg aaatcagttc ttgtaaattg tttcagcttg atcactctca ttctcctttc
     5521 acacaacctt ttatacacct tcaaatttat ttctatatga aaaaatatat tcccttttaa
     5581 acaaaataaa aagccattca taagaatggc ttagcatcaa taaagcataa ttactcttta
     5641 tttgctacgt caacaccgtt aaaatcaaac tcatcagcaa cagttgtagc aggtggtaaa
     5701 atcgcttcaa ttttacaaag agatataatt gctgcaactg aaccaggaat agcagccagc
     5761 ttaacaacat cgcaagttac agaagaaaca gtacctatat aagtacgtcc ttcagtgtta
     5821 attcgcactg ttttattaat taatttttta agttcgtctc taattccttg tacacaagag
     5881 ctgtcacatt tctcatgctg ttctttttta cactcttcaa aaacatccca acaatcatca
     5941 tgtttacacg tacatttttt tctacaatta ttaaatcgag aacccaaaac ctcaccccct
     6001 aatcctttct attagtaaag tatgtccaca agcttaaaag tgtaagagac aaacacatag
     6061 aaaggaaaaa acaaacaatt gtattagaca ttcttttctt tattaactat aaaaacaggc
     6121 ctctaacaat ttgaagcttg tttaatgagg ggaattggat ttaattctgc tgaatttaaa
     6181 gtttagacaa cctcttataa gtcagctcct ttaagagtcc ccagcttttc ctattacttc
     6241 acatatacca tatacatagg ctttgtttgc attaatatag tatatttttc ctttgctgtt
     6301 gtgaaatatg cattaagaaa agcgtactcc aaaataagat attatttaaa atcagaatgt
     6361 tttcttcaac aagtgtttgt tgattaatgt cataaccagc agttctctcc actacctttt
     6421 gaaaattagc atagtttgta tgaattctat agctagtaga aagcactcta tcatataaag
     6481 gtaatataat aggttaataa acaagccatt cttttactaa aacatagaat agtatgaatc
     6541 ctattgaagg gaggtataaa agaatgtcct ggaaaaatga ttgctggagt tctaagaaaa
     6601 agcattgttg tgatgactgg tggaaatcta aagaaaagaa tcattgtgat gatgattgga
     6661 gttctaaacg aaataagtgt cgttgtaaat gtttctttat ttgttttcat tgtaatagaa
     6721 aaaattggta atattttcga tatcgactta aaagagagaa catgtctttt gtgaccgata
     6781 aatactagaa tgtaatatac aaaaagctga ctnnagtcag ctttttgtat attaacacgt
     6841 agagatttat tttaatatag ttcttattag aaaaagatta ttttatatag attactataa
     6901 gcatccataa agccaaggcg ccaatgatag cgagcgctat acgtgtagat agtaccctta
     6961 attcaaagtc tgttttcttg gagggttcag gatatgcaat tatgtagatt ccctttaata
     7021 gtgcaagcca tgcaataacc gttaggaacc cctgccagtt gaatacccat acattatgta
     7081 gaattacact acctaaccct aggaaaatcg atagaaaacc atacataata ccaaatcctc
     7141 tgtcttcaac cactaatttt ttcaattcac gtagtaccga tggacgtacg aaaagtattc
     7201 ccgatacgat aaccgttatc catccccaaa acaatcctaa aaaagtacta gtttccatta
     7261 ttagttcact cccctcaatt atttatattt cagatatttc cccctttaga acaattccaa
     7321 catctttata tataggctaa attctgctct tttttaatac aaacatggca tactctatgc
     7381 ccatccttaa tcacctcatt tctctacaag atgaaatttt catatcattc ttcatcatct
     7441 atccgaatca accgaagtcg ctttgtacta ttaccgcaca ctttttcata gcttggagct
     7501 aacatgcacc aaagccaata taatgattta ttcgcctttt cactaacctt taaaattgtc
     7561 ccctctgtaa taaaataatc accttgatac aatgtatact cgcttgtccc atggaatcat
     7621 cattattccc ctccctatta aaatagcgtt tttgtttcaa ataatgctct cattaatttg
     7681 gacgcattta ccagtatatt taccaaaaaa ttcatgatat cgttaactag tcgagtacgt
     7741 cattacttga cgattaccct taggatcccc gcagacaatc ggggttcctt ttatttaaat
     7801 aaggattttg tttaaacctt acaaaactca cttatattaa actatcttct aaaattccca
     7861 ttgaacattt ataatacttt taaacagttt aaattctaca atcagtaatg gaggcatttt
     7921 aatgggaaac atcccaaaaa tatcatcaca acaatcaaat cctaatatac cctcacagca
     7981 agtgaacgct aacaccaaac aaggtaataa taaaataaca agacgccgta ttataactac
     8041 tttagctttt atattaccta taatttttgt ccttcaatat tctcttaata accagcaaga
     8101 aatgattaaa gaaaaacaaa tcacggttaa tacggagcaa caaaaattat tttctgtaaa
     8161 gaaggatagt cattccctta aaaatgatgt taaggcttta acaagtaatg aagaagaaat
     8221 tttaaaattc gcaaggaaac tgtatggatt ttctaaaccg aatgaaacta tatttcaaat
     8281 aactgaataa aattatactg tattacctaa aaggcgattt gaagataatc gcctttttat
     8341 atttaatttc taaaggaatc ctactaatct ctctttctat catataacta ctttatttaa
     8401 tttgttaaaa tacaaccgct tgtccatttc actttgctct gtcattacat ttactattag
     8461 taatacgatt tttagaggtg ataaataatg gacgagtttt tatcttttgc tgcacttaat
     8521 ccggtttcta ttggacctac acttccacct gttcaaccct ttcaattccc taccggtccc
     8581 accggttcta caggagctac tggatcaacc ggatcaactg gacctactgg gtcaaccgga
     8641 cctactgggc ctaccggacc tactggacct actgggtcaa ccggacctac tggacctacc
     8701 gggcctaccg gatctactgg gccaactgga tttaatcttc ctgctgggcc tgcatctatt
     8761 accttgactt ctaacgaaac cacagcatgt gtatccactc aaggaaataa tacgttattt
     8821 ttttcgggtc aagtattagt aaacggtagt cctactccag gggtagtggt cagtttttca
     8881 tttagtaacc cctctcttgc tttcatggtt cctcttgctg tcattaccaa tgcttcaggt
     8941 aactttaccg ctgtatttct agccgctaat gggcctggaa cagtaaccgt tactgcttca
     9001 cttcttgatt ctcctggaac aatggctagc gtcattatta ccattgtgaa ttgtccgtaa
     9061 tgattttatt tttaagagct aaacaatttc taataagatg agcactgatt tgcagtgctc
     9121 ttttttatca ttgggatgtt actttcaaat gagttttcgt aacaccctag taaaataacg
     9181 tttttattaa gaactaataa tctttatatt tcttaaactt gtcatcacaa gtaattttta
     9241 taattagtta tattctcaat atattttatg tatataattc cattcaaaga tacataatac
     9301 ccacgtaact acttaaaaac acttcgtttt atatctaagt taaaaaagga gctacataac
     9361 atggataaaa aagatctatt aagtcaacaa cttgaacatg tgtcatcaga tgcgttgaat
     9421 actcctagta aggcccaaga gcaaatgcaa gaagcatctc agcaggcaca tgtttcaaac
     9481 aaaaaggaca gtactcaatc tttacatggt gaagatttac caatttcaga cgtatataga
     9541 acaacgaaca aacagtaaat ttaaaaggga aaaatcttaa gaaccagtga acttaattct
     9601 tttccctttt cctatttaaa taacactttt atatgaaacc cgtacacatt tttgacacat
     9661 ccactatcac aatctcctga aaattcgtga taatattaat ttgtcggata cgccaaattt
     9721 cgacattgaa cgacaatgat atctccctta ttgaatccct gtcccccagg gatttctcct
     9781 tttattcatt acttttttct tcactaaatt ttcattctta acaaaattca atcactccat
     9841 taaatagaca gccatagtat cctattttga taaaaactaa aaacaaacag atatacttaa
     9901 cactaatagt agatttttta acttcaaatt tactttttct ctcttatctt tttgtaaaca
     9961 ttaaaaatga gctctattta catagagctc attcgtaatt ttatagtttg ctagactgta
    10021 acccctgaat aaacggaact acttcaggat ttacaagtga cgataaatct cctaactctt
    10081 ttcctaagta agcagcttta atgacgcgtc gcattacttt agaattacgt gtttttggta
    10141 aatcttctac aacgtgaata tcctttggac acaatgcttt tccgatatga gagtttacta
    10201 aactcattaa ttctttcttt aactctcctg tgaatgttac attgtccctt aatactacaa
    10261 aacaatgaca aacttcacct tttacatcat caggtacacc aatcgcggca gcttctatga
    10321 catcattatg cttcacaaga atagattcat attctgcagg tccaatacgt tttccagcaa
    10381 tgtttaacgt atcatctgag cgtcctgtaa taatatattg ctcaccatca taaatcaccc
    10441 agtcaccatg aacccattta ttttcaaaac gtgaccaata cgtgttcaca taacgctcat
    10501 cgtcttccca aaaacttttc gtcataccaa cccaaggttt ctctaaacat aattctccaa
    10561 cttcatcacg aattggattg ccttgatcat cgagcacaac tgctgccatt cctggtaaag
    10621 acgcgttaaa actaatcggt gcaatcggtt taataaggac gtttccgaaa atcccaccag
    10681 aaatttcagt tccgcctgaa tagttacaaa ttggtacatt attttttcca actgtttcaa
    10741 atagccacat ccaaggatct ggattccaag gttcacctgt tgatgcgaat acttctaaac
    10801 tcttgagcga atgtttattt acatactcat caccctttgc cattaacgca cgaattaatg
    10861 ttggtgatat accgagatgt gtaatttcat atttatcaac ggtctcccat aaacgatctg
    10921 cttctgggaa atctggaaca ccttcgtaca taaccatcgt tgctccatta atgagagagc
    10981 cgaatagtaa aaacggtccc atcatccagc ccatatcagt tacccataat acgcggtcac
    11041 cttgtttgat gttcattcca aatcctgcat caaatgcaga tttcaaaggg aaaccagcat
    11101 gtgtatgtac tgttcctttc ggtttcccag ttgtacctga tgtataaatg agcattaacg
    11161 gatcatcact attcatctct tcagcatgtg taaatggttt ttctttttct agcgcactcc
    11221 atgggaaatc ataattatgt ggtgtaaaat catttcctgc atgacgaaca ataacaactt
    11281 tttcaacagt tggacaatgt ttgcaagctt tatctacttc gtcttttaat gaaacaactt
    11341 tacctcggcg tgaaaaacca tctgcagtaa tgatcatttt tgatcctgcc gcttgtacac
    11401 gagtcatgac tgcatcagac gcaaatcctg agaatattgg tgaaataatt gctccgattt
    11461 tcataacagc taacattgca acaactgttt ctggaatcat cggcatataa attgttaccc
    11521 ggtcaccttt ttcaataccc gcatgtttca aaccgtttgc aacgcgactt acccagttgt
    11581 caagctcttc atatgtaaat gattttgaag ttccattttc tcccacatac tgtagtgctg
    11641 gttgcgttct tgtttcatca tctgcaagcc agcgtgataa aactgattct acaacgttac
    11701 atgttccgcc attataccac tgtgcaaacg gcgtaccatt ttctaaatct agcacttctg
    11761 tataaggctt catccattga tagccaaccg ctttctcagc ttctccccaa aaccaatctg
    11821 tttcttcaat agatttatta taaaacgttt cataatcttc atagcccaat gatttcatcc
    11881 aaccatataa acgcgttttt tctttatatt cttctgttgg aaaccaaact gcttgtttca
    11941 atgttttccc ctccttgact ttttgagcaa gaaagcccta aatagggctt ttaaactgga
    12001 taaacaggat gtttacgatc tgtaaatact tgatatttac tcatatacat ttcgaagcgt
    12061 ccttttaact cttctcttaa attgtttgga tgaacaatac catcaatgac catctctgat
    12121 gctaaatggt aaatatcaat atctttctta tactcttcgc gtttttcagc aatgaagcta
    12181 tcacgctctt cttctggtaa agctgcaatc ttatttgcat atacagcatt gactgccgct
    12241 tctggaccca ttactgcaat agaagctgtc ggtaatgcta ggcagcaatc tggttcaaag
    12301 gctggacctg ccattgcata taaaccagca ccgtatgctt tacgaacaac gatagaaatt
    12361 ttcggtacag ttgcttcact cattgcagaa atcatctttg caccatgacg aataatacca
    12421 gcacgctcta cttttgtacc aatcataaat ccaggtacat ctgcaaggaa taacaatgga
    12481 atatgatatg catcacataa attaataaac ttcgctgctt tatccgctga atcgtggaat
    12541 aatacgccgc ctttcatacg cggttgattt gcaataatac caactggctt accatcaata
    12601 cgtgctaaac ctgtaattag ttcttgagca aatagttttt tcacttcata gaaagaacct
    12661 tcatcaataa ttctgttaat aaggtctttc atattgaaag gagcattttg attttctgga
    12721 atgatttgtt ctaacgtttt ttcgaattgt ttcggttctt gaggtgtaac caatggagtc
    12781 ttctctaagt agttgtttgg aaaatatgaa atgtattgtc ttgcttgtgt aatcgcatct
    12841 tcttctgttt tacataaaac atctccgcat cctgatacag agcaatgcat acgagctccg
    12901 cccatctcct ctaaagttac cttctcgccg ataaccatct ccgccatacg aggagaacct
    12961 aagtacatag atgcatttcc ttctaccatc ataacaatgt cacaaaaggc tggaatatat
    13021 gcgccaccag ctgccgaagg tccaaataat aagcatactt gaggaacttt acctgataat
    13081 ttcacttgat tgtagaagat tcttcctgca ccgcggcgcc ctgggaacat ttctacttga
    13141 tctgtaatac gcgctccagc agagtcaact aaataaaata acggaacacg taatttttct
    13201 gccgtttctt gaatacgtaa aatcttttca actgtacgtg cgccccatga tccagccttt
    13261 accgttgaat catttgccat tacgcatgca gtacgaccat gtattttacc cgttgccgtt
    13321 ataacaccat cagcaggtaa tcctgtttgt tcacaatttg caaataatgc atcttctaca
    13381 tattcaccat tatcaaataa aagagctaag cgatctcgaa cgaatagttt tccttttgct
    13441 ttgttttgtt catgatactt tggtgcgccg ccttgtttaa tcgcttcaac tcgttcttca
    13501 aatgtattcg attgttgttt ttggtctaac atatttactc ccccttatac attggtgtgc
    13561 gtttttcctt gaatgcttgt aatccttcta atctatcttt cgtatggatt acaccttcat
    13621 acgcttgttt ttccatttgt aatccggtat gtaaatcaac ttgaataccg tttgaaattg
    13681 cttcttttgc taatcgaaca gcaataggac cattactagc aattttctct gctatttcaa
    13741 tcgctttctc ttcaagtaaa tgagctggta caacaaattc tactaaacca tattcttttg
    13801 cttcttgcgc tgaaatacgt ctgcctgtat aaattaattc tttcgctcta ccaacaccaa
    13861 ttaatcttgg taaacgttgc gtaccacctg cccctggtat aattgcaagt gtagtttcag
    13921 taagaccaag acttgcagat tcagccgcaa ttctaaaatc acaagctaaa cttaattccg
    13981 taccaccacc aagggcgatt ccgtttatag cagcaataac tggctgtggt aattgttcaa
    14041 ccatctccat agtagtgcga atcatactaa cagcatggcg aacttgttcc tcattcatac
    14101 cagcacgttc ttttaaatca gcaccagcac aaaacgcttt ttcaccagca cctgttaaaa
    14161 taactacacg agtattggac tcttcactta tttgagttaa tatgttttgt aactcttcta
    14221 ataacgctaa agataatgag tttgcttgtc tttcacgata taacgaaatc tttataacgt
    14281 gaggtgttac ataattaact gaaatgtttt gtagttgtag catcttctca cctacttatc
    14341 gttttatgtt gaagcgctct atacacatga ctcggtaatt ggatatttaa tttactttga
    14401 atgaattgac tcgctttcaa taacttctct tcatcaatat tcgtttggac ccctaactta
    14461 tgaagcatat gaactaagtc atcggttgca acattgcctg atgctcctgg tgcatatgga
    14521 catccaccaa gaccaccaca agaactatca aatgttgtaa taccatattc taatgactta
    14581 actacattcg ccagagccat tccatacgta ttatggaagt gcattgcaaa ctgcgaagca
    14641 tcatatttct ttaataaatg ctctaatact cgctctactt gtagtggatt cgctacacca
    14701 atcgtgtcac caagagatac ttcataaatg ccgtatgaaa atagttgatt acataattcg
    14761 tcaactgctg tggcacttat atctccttca taaggacatc caaatacagt agaaacatag
    14821 cctcttacct ttttcccttc gaatattgcc tgttttgtta tatcttcaat tacaactaat
    14881 gcttctttaa ttgatttatt aatattactt ttattatgag attcacttgc tgataaaaaa
    14941 acattcacct catctacatt ttgcaaaaaa gctcgttcca aaccattttg atttggaaca
    15001 agcgctgcat atgtaacatt tggatccctt ttcagctcag aaaacacatc atttgcatct
    15061 gctaatgcag ggacccattt agggtgaacg aatgaggaaa cttcaacgta cgataatccc
    15121 gcctctgtaa gtagttgaat ccattttact ttatcttttg tgccaacaat ctttttttca
    15181 ttttgtaagc catcacgtgg cccgacttct ttaatgacag caaaattagg tagtttcaat
    15241 tcgcttcccc ctatatctcc ctattcaatt tctagtaata catctccttc atttacaaaa
    15301 tcgccttctt gcacattaat tttcataact gtgccagctt cttctgaaat gattggaatt
    15361 tccattttca tagattccaa aatgacgaca tcctgctctt cctctactgt atctcctact
    15421 cctacaacaa tcttccatac atttcctgcc atcgatgcat ataccttcgt catcattttt
    15481 tcccccttaa tattgttaaa tcttattttt taacgagttg tttcgttaca aaacccgttg
    15541 tataaatacc acttttaaac acatcgtctt ccaatacttg aagtagcatt ggcgtgttcg
    15601 ttttaatacc ttctactttt aattcttcta aagcatcatg taattttgaa atggcttctt
    15661 cacgagtttc accatgagca atgactttcg caatcattgg atcgtagaaa ggtgtaatcg
    15721 ttacttgatt ctccaaaaag tgatcaatac gtacattgga tggaagcgtt aaatctgtaa
    15781 ttttcccagg tgatgggaag aaagttttcg gatcctctgc ataaatacgt gcctcaatgg
    15841 catgaccact acgttttaca tcatcttgtg taaatgatag tttctcaccg tatgcaatta
    15901 gaagttgttg ttctacaaga tctaaaccag taatttcttc tgtaactgga tgctctactt
    15961 gtaatctcgt attcatctct aagaaataaa agttcttctg atcatctaca agaaactcaa
    16021 ctgtacctgc atttgtatag cctagagctt tggcagcttg tacagcaact tcccccatcg
    16081 cttttcgcgt accttcatct aaaaatggtg aaggtgcttc ttcaattact ttttgatttc
    16141 ggcgctgcac tgaacattca cgctcccata aatacactgt attaccatgt gtatctgcta
    16201 aaagctgaat ttcaatatgg tgtgcatctg caatatagcg ctctaaatac atttctccgt
    16261 taccgaagaa gttttgtgct cttgttttgt tactttcaaa tgctttggtg agcgtttgct
    16321 cagtttccat caactgcatt ccaatgcctc cgccgcctgc ggatgccttc agcattaatg
    16381 gataaccaat ttgttttgca atttcaattg cttcttcagc agtttcaata tttgtagtaa
    16441 tacctggaac tactgggaca tctgcagctt gcattgcaat acgagattcg attttacttc
    16501 ccatcttcgt aataatttct tcagatggac cgataaatac aattccttct tctctacagc
    16561 gaaccggaaa agatggattc tctgataata atccatatcc cggatggatt gcttcagcat
    16621 ttgtcttctt agctatttca ataatttttt caagatttaa atagctttct tggacacgcg
    16681 gtccacctac taagtaagct tcatttgcca tttttacatg tagggcattt tcatcagcct
    16741 cagaataaat agcaacagta cgaatgccaa gtttttgaca agttttcata atacgaactg
    16801 cgatttcccc gcgattagca attaatattt tttgaaacat agtgattcct cctttttatc
    16861 tacatcctaa atgtcttgca attacgagac gttgaatttc agaagttcct tcaccaattt
    16921 ctaatagttt tgcatcacga atatgtcgtt ccacttcata ttcacgcata tagccgtatc
    16981 caccgtgaat ttgtaccgat tgatttgcaa tacgactagc agcctcagat gcaaataact
    17041 ttgccatagc cgcttcttta ccgaaaggtt tatcattatc ttttaaccaa gccgctttat
    17101 gtactaaatt acgtgcaagt tctacttcag tcgccatatc agctaattta aattgaatcg
    17161 cttggaaatt agagattgac tttccaaatt gttgacgttc tttcgcatat tgcagcgcac
    17221 gttcaaatgc agattgtgca atacctactg ctaatgctgc gattgaaata cgtcctccat
    17281 caagtgtata taagaattgt ttaaatcctt tatttacatc accaagaata ttttctttcg
    17341 gtacacgtac accatcaagt acgatttcac atgtattaga agcacgaaca cccatcttat
    17401 cgtaaggact tgagatcgtt aatccttcac ttgtagtcgg tacgataaat gccgaaatac
    17461 gttttctacc attatcttca acaccgttga tagcggttac aataattgta tttgcatact
    17521 ctgcatttgt aatccaacac ttttcaccac taataacata ctcgtcccca tctaatacag
    17581 ctttcgtttg tgtgccgcct gcatcagatc cagcgttcgg ctcagttaaa ccgaaagcac
    17641 ctaatgtttt acctgacgcc attggaacta aatatttctg tttttgttct tctgtaccga
    17701 aataataaat tggagaagca cctaatgaaa ttgttgcagc ataacttaat cctgtcccac
    17761 cacaagcacg accaatttct tcaactgcta acgcgtacga tacagtatcg ccacctgaac
    17821 ctccatactc ttcagggaat gggatgccta ataatcctag ttcgcccatt ttttgaaatg
    17881 tttcatatgg aaattcccca gttttgtcat aatacacagc tttcggtgcg atttcctttt
    17941 cagcaaagtc acgtaccatt tctttaatca tttgtttttc gcgagttaga gtaaattcca
    18001 ttccgctaca caccccttat cgaatattga gtttcgacag cgtgcgagtt tctactacaa
    18061 acattacttc ttaaaagaaa tgaatattag ttagacaatt gctataattc tgtcataact
    18121 taattttaaa acagattctg taccaatgca caaaaaaatt cctacattgt tctacaacaa
    18181 cataggaagt ttcgtgtcga attatgtaat ttattgttta ataatctcta ccttttcccg
    18241 aatccgaaat ttctactaat gcttcagggt atggttcaaa atatgtttgt cttaataaat
    18301 acttatcgtc aaatcgaatg gcccatgatt ttaaaattgt aagtaagcta ctcagcggga
    18361 ttttcttttc tttatatttt tgtatcagat ctaaaaaatg atctttttct tgttttttca
    18421 gttttgtttt aaaatatcca aaaatatgct cacatacatt tacattcgat gtatagcggg
    18481 gtgttcgcat aaataattca tatagagtct tctcatattt atcaaataca atttcaatct
    18541 tttcattctt ttgatttgca ataatacgcc ccaattcctt ttgttttacc tgattatatg
    18601 ccataaataa atatttattg tccgactgaa acgatacaag gtctttcata tttttattgt
    18661 gtttgatcat tttgtaatat gcgattgtaa ataaccttgt aaagaaatgt tctctaataa
    18721 taaaattcga caatctaccc tcttcttcaa ttggaagatg cgaaaatttt tttattactg
    18781 ctccaccaaa taagccagac ccctttcctt ttgctggtgc tttttcaaaa ccagaataaa
    18841 ttttcacatc acgcgtacca caactcggcg aacgattctt taaaataaaa ccatccacat
    18901 cagatatcgt ttgtaaaaag acatatgaaa attgctccat tttttcagtt acatcttctc
    18961 gtgtcgacgg ctgtacaagc ctattcacac cattttcttc tacaattctt attgtttcac
    19021 gaggagtccc caatccgatc tcgacttctg gacaaacagg tataaatgta acaaatggct
    19081 gcaaatttcg tattgttaca tctggtatca tctctgcatt ataacgacag gcatcaaatt
    19141 ctaaacattt acttacaaca attgttggtt ttgcaaattg ccgcatttca ttacctccat
    19201 ggtatcaatc catacaatct aaattgtact gatattagta tcttaagcaa agtctgttta
    19261 tattgattat ttttataata actataaatt taatgctata tcaactgcaa ttcaaatcta
    19321 tttcgtatat gtattaacaa gttcttgtac aaacttgtta acactttttt ctctaaacac
    19381 aatccatctt tactagcata gttacagatt ctttcctttc ctctttacat ttaaattaaa
    19441 ataagcctta atatgaattt taatcccaag ttatttagaa tatattcttt aaatttgtac
    19501 attatagact gagaaagtat tacttgtagt tagggtgttc caaatgaatt ttagaaacct
    19561 actttcttta ttacggaaca ttttcagaag tattttttct ttggtaagaa atatttcaaa
    19621 aaatccattc agtttaagga ggcatattaa aatgggagta ttaagtggta atccccaaaa
    19681 tgaaccaatg cattacggag aagtctttgc aatttggagt tatcttgcag gggcacaagg
    19741 tgcaattgct ggttaccaag ttcttgtcaa tcatactgga gacgaggact taaaaaagtt
    19801 tttagaaaat cttatagaaa atgatatcca atcagaagtt gaagaactaa aaaacttgtt
    19861 aaaatcaaac ggtgtggcat taccaccagc acctccagaa cgtccagttg catctattga
    19921 aacaatccct cctggtgctc gtattaatga cgcagaaatt gcagctaaag tttctatgga
    19981 tcttgccgct ggactagtag catgtagcca agcaatggga caatcacttc gagaagacgt
    20041 aggaatgatg tttggacaat tccatatgaa aaaagcacaa gcaggtgcta cattactacg
    20101 attaaataag aaaaaaggtt ggattattcc tcctccttta catgttcttc aatctgatca
    20161 agcataacat ggcgtaagcg gttaactttt gttaaccgct tcattatatt tacctgtccg
    20221 tttaataatg gaaattaaag atagttctaa taactttaac tttatgattt ggatactgtg
    20281 atacgaataa tgtacaaaag tactggagaa attaatacat aagaaaggag gggaaaacca
    20341 tgaagaagaa attatcatct attttaagtg ttttagcact atctattatg tttttaggta
    20401 catctgcaca agctgaatac gatggaaata atatgaacag agttaataac actgacattt
    20461 caactcgagt taatgacaat aacttagaca gagttaataa tgatgtgaga actcgaaatg
    20521 taaatacgac aaatgatttg aatgataatc gggataaaaa taataattgg gcttggctgg
    20581 gtttattagg tctagcagga ttattaggtc ttagaagaag agacaaagaa acacgctaat
    20641 tcagaatatt tttagtaaac aagtacttat ttatcaaaag tatataatga atataaatcg
    20701 cctttttcaa ggcgatttat tattttactt aaatgtaaga tatgtaattc atacttcgac
    20761 gattaaattc gtggtgttaa tccgtacaat ataaattgaa tcgtattttc aatttccact
    20821 tcatcatccc atttttcttc aggcaataat aaaaaccttg ttaatagtaa acctaataca
    20881 gctgataaag taagtcgtaa aacagaagaa gggggcattt caataatttc cccttcttct
    20941 tgaaacttta caatcaactt tttaaaatgt gaaagtaact ctgtttctac taaatgttgt
    21001 atttcatttt tcagttcccg ctgaaatggc acttcttgaa ttaatatttt tatcattgga
    21061 aaatgctttt ttgcaaattc aaatctatta tgaataacaa ctcttagcag cccttcatac
    21121 gattcatact ccgatttaaa tatttccttt gcgaaggctt gtacaaaaaa tggtgcagca
    21181 aactttgtta atgttggcat gacgactgct aacaataaat cttttttcgt tttatagtag
    21241 cggaagattg ttccttccgc tacaccagca cgctttgcaa tttcacttgt agaagttgat
    21301 gcatatcctt tttctccaaa catatcaaca gctgcctcta aaatacgcat ttgacgttca
    21361 tttcgtttat ccgtattagt tgcggcaatt aattcatcca accaatcctt cttcatctat
    21421 aatgcccctt tgtatcatca ttatattttc cgatgtttct ttaatgcaaa tacattccct
    21481 attgcaaata atagagaaaa aagtagtaat acagtaagat ttaatgcaat ctctgtaaat
    21541 ccttgatttc gaatcatcac ttgtctcatt gcgtcagctc catatgtgag cggaaataat
    21601 ttccctaaca tttggagcca cttattcata gattcaattg gaaacaaccc agaaaagaaa
    21661 atttgtggca caatgacaag cggtataaat tgaatcattt gaaattcatt atttgcgtat
    21721 gctgataaaa atgtccctaa agttagtgct gttaaagaaa gcatacatgt aataagtagc
    21781 gttagccata tggagccagc tacatacaag tctaaaatat aaactgaaaa attcacgatt
    21841 ataattgatt gtataaatgc aaagattcca aaaccaataa tatatcctac aactatttcc
    21901 catcttctca ctggagtgga caataatctc tctaatgtac cacttaaacg ttctctaaca
    21961 aaggaaactc cagataatat aaatacaaag aaaaatgtaa agaaaccaat caatacgggg
    22021 ccaagcccat caaacattgt aaagtcttta gagccatgta agtaatttac ttcaggcttc
    22081 ataactgata catcattctt ttctgaactc ttttgtaaaa cttgaagtac agcacgattt
    22141 tttgatgaat cacttccttc taataaaaga ttcattttcc cattctctaa ataaattact
    22201 gcatctacct tttgctgttc taactctgaa attgctttct ctttgccgta ttcataaatt
    22261 gaggcttctt gagttttcat tgtttttaca atgggagcag gcaaatcaac tacagcaata
    22321 tgcggtacat agtctttttg tgtaaacaca agcgacagta accaaagtaa taacattggt
    22381 gccccaaaca tcatcgctaa cgaacgctta tctcgaaaaa attggcgaat aatacgaatg
    22441 attacaccag taactctcat gatagggcca cctcttccaa caaaaagaca tcttcaatcc
    22501 gtcctgatga tacccgtttt ttcaattctt caggtgttcc agtcgcaact agctttcctt
    22561 ctctaattaa tcctagccgt tcacaaaatt cagcttcgtc cataatgtgt gtcgttacaa
    22621 taatagtcgt gcctttcttt ttcaaatcat aaaatttttc ccagattgtt tttctaagaa
    22681 gtggatctat ccccactgtt ggctcatcta aaattaatat ttcaggttca tgaaggagtg
    22741 ctatcgctaa tgataaacgc ttcttcatcc cacctgaaaa atgttgcact tgctgtctta
    22801 tatgttgtga taattgtaca aggtcaaaaa cctcttcgat tctttctttt ttatgttttc
    22861 cctttaatcc atacatcgtt gcaataaaat ctgcattttc atatgctgat agttcttcat
    22921 ataatgcatc agcctgagcc atataaccaa ttcttttcat ttcatttaaa ttaggcatgt
    22981 tcgtgttgta aacaagcact tcaccttctg atgcctcatt aatacctgca atcaatttaa
    23041 taagagtcgt tttccctgaa cctgaaggcc caactaaacc aaatatctct gctttttcaa
    23101 cttgcaatga aagattgtgt aacacttctt ttttcccaaa actttttgac acggttcgca
    23161 aaataatgga aggttgctgc acgttttatt ccccctttta taaaaaatga gtgagtactc
    23221 acttttattt tactcttgcg taattatatg tcaaacttca ttgattagta tgtattttca
    23281 atcttaaaca atgaaacaga gtcgatatta gaatatcatt tcctaaaatc gactctgttt
    23341 catttaaatt atttatttac tttacgtttt taaattcata tatttcctaa ttctagcaac
    23401 atctaaagaa tattcgataa ctaattgctg taacggtaaa ataactgtgt caggatataa
    23461 atgtgcatat tgtaatgttt ctgcatattt ttctaacctt ttttctaaat actttataat
    23521 ttgatcagga tgacttacta ataaacattt acaataataa tgtatttgtt cctcaatcgc
    23581 cgtatactct tcaatttcat attctttatg catgtgtaca cccctttaag ttttttactg
    23641 aattgcttat cacacttttc actcgactaa tttttaagtt ttttgattat ttacactata
    23701 acaaactctc cgggtcaaat tttgttactt tatgtaacgt agaaaatttt taacaaaact
    23761 gtaatgttaa cttgtataaa atgcatatgg cctatttttt ctgtacaaaa aatcgcacag
    23821 ttcaatttaa ctgtacgact acaagttctg gcctattaaa aattctttgc ggaatgatac
    23881 tattgcctaa tcctctactt actaccatag acgtattttg tttttcatat aaaccggctg
    23941 tatatgtagg gaacatccct tgattcggag caactaaccc tccgataaat ggcaatctaa
    24001 cttgccctcc atgagcatgc cccgataaca ctaaatctat ttgttcatca gcatactctg
    24061 ttaaaaattc aggcctatgg gatagtaata cattatatgt atccggctgc gtttcaattt
    24121 ttgcttttat aatttcatct tttacaacat ttccttcatc acgatttcca gtaacaaatt
    24181 ccggatcatc aataccaagt aaatttattt tttgttctcc tttttgaata gttacatgtt
    24241 catttcttaa aacaataaca tgatgtttct ttaattcttt ctctaaatta ttatatttac
    24301 ctgaccattt ttcatggttt cctgtcacaa aatagacagg atacttcttt acaagctttc
    24361 gtattaattc catactaact tccggatcgt atgatttact gtcaattaga tcacccgtaa
    24421 tagcaataat atcaggattt atgcttttta ctttttgaat taaagtttct tgattgtcgc
    24481 caaatttttt attatgtaaa tctgaaattt gtagaatttt aaaaccttta aaagaagagg
    24541 ggattttatt agatgttatt ttaacctcag ttatactaat taaattgttc tgtacatata
    24601 aaaagatgct aaaacctact aatgtagcaa taagtaatat aattctttta gccttcttgt
    24661 tcatatttcc tcctaaaatt ttgatcagta ctacaattct caataaacat tccgtgccct
    24721 tcgaattcag aataactgaa actttttaat tgatttgaag tattttcata gtgttatacg
    24781 tctctaatga acacttagct gttttccaat cccattcgta ttaactgcta taaagtggag
    24841 ctttaatatc ctaggtttcc ttcatgagtg tatgatatca tgctcatttt ccagtgaatt
    24901 tatagcgaat cgctggaagc tcttcatcat attatcattt atcttactta gtttaataac
    24961 gatataatga taattcctat agtcttttat aaaaaaattg tgtatttttc tcgaagtata
    25021 tacgacattt gcttgcaaat atattattac cactacgatt ttaatttatt taaaacgtac
    25081 atagagagaa ttgaaacact aaattcactt atgaaaagtg attattacaa tattaattag
    25141 aaaattgaaa taatatgtgt agatagatat cattgtaaat gcatatataa ttgattttaa
    25201 ttttctgaca tattttcaca taattttcaa actaatttt
//
