LOCUS       NZ_NVOB01000040        25239 bp    DNA     linear   CON 01-APR-2024
DEFINITION  Bacillus toyonensis strain AFS095804
            AFS095804_119_G5_Contig40_140618, whole genome shotgun sequence.
ACCESSION   NZ_NVOB01000040
VERSION     NZ_NVOB01000040.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus toyonensis
  ORGANISM  Bacillus toyonensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 127335)
  AUTHORS   Bleich,R.M., Grubbs,K.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Large-scale bioinformatics analysis of Bacillus genomes uncovers
            conserved roles of natural products in bacterial physiology
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 127335)
  AUTHORS   Bleich,R.M., Grubbs,K.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Direct Submission
  JOURNAL   Submitted (07-SEP-2017) Chemical Biology and Medicinal Chemistry,
            UNC Chapel Hill, 125 Mason Farm Rd., Chapel Hill, NC 17599, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Assembly Cell v. 4.2.83
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 54.85x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002552225.1-RS_2024_04_01
            Annotation Date                   :: 04/01/2024 01:56:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,087
            CDSs (total)                      :: 6,001
            Genes (coding)                    :: 5,774
            CDSs (with protein)               :: 5,774
            Genes (RNA)                       :: 86
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 227
            CDSs (without protein)            :: 227
            Pseudo Genes (ambiguous residues) :: 0 of 227
            Pseudo Genes (frameshifted)       :: 103 of 227
            Pseudo Genes (incomplete)         :: 136 of 227
            Pseudo Genes (internal stop)      :: 60 of 227
            Pseudo Genes (multiple problems)  :: 61 of 227
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:33:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 71768
            Orig. end                         :: 97007
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NVOB01000040.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25239
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="2"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..25239
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25239
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:15239](-)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15239)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            848..1864
                     /locus_tag="CON62_RS27115"
                     /old_locus_tag="CON62_27120"
     CDS             848..1864
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160038.1"
                     /locus_tag="CON62_RS27115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27120"
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="WP_001160071.1"
                     /transl_table=11
                     /translation="MQFLKKFTILLLSFIITALIVLYFYLYVNGPIIQAKSAILIDANS
                     GEVIYKKNEETPIQSATLSKLMTEYIVLEQLNDGKIQLDESVKISNELFQAETTPMQVT
                     TKDKTTVRDLLHALLLTGNNRSALALAEHIGGNEDNFTTLMNEKAKQLQLSQPSPFLNS
                     TGANQDTNKQSNTTAKDAAKLATHLVKDFPNVLNMTKLTSYQFTFKNFQVFNTNKMIYS
                     LNENIKFQGVDGLQTSFSTNGNNSFVGTAKLGDTRLISVILESDEENTTFIETKKLLQY
                     GFEPSSYSALQAFKDTLTSWAILLQFKNLIIQTMMIFFIITILMFLHLRQRKSEDFN"
     gene            complement(1923..2381)
                     /locus_tag="CON62_RS27120"
                     /old_locus_tag="CON62_27125"
     CDS             complement(1923..2381)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288270.1"
                     /locus_tag="CON62_RS27120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27125"
                     /product="DinB family protein"
                     /protein_id="WP_000288864.1"
                     /transl_table=11
                     /translation="MYTVFQYNWQVREDWFKWCEQLTVEELLSKRVGGVGSILETLFHI
                     VDVEYSWICDLKGKEVDEPQFKDYQSIQKVKALSHLYNKDLEGFLQSWTEDLENKILKV
                     SWTDKEYKYGEVLRHVVVHEIHHIGQLSIWARELNLQPVSANLIGRGL"
     gene            complement(2384..3124)
                     /locus_tag="CON62_RS27125"
                     /old_locus_tag="CON62_27130"
     CDS             complement(2384..3124)
                     /NRPS_PKS="Domain: Abhydrolase_1 (27-133). E-value:
                     1.4e-13. Score: 43.0. Matches aSDomain:
                     nrpspksdomains_CON62_RS27125_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237666.1"
                     /locus_tag="CON62_RS27125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27130"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_000237664.1"
                     /sec_met_domain="PF00561 (E-value: 2.8e-10, bitscore: 33.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKCIEEYVQVDDFKMYTKVFQGKKRQPVIIMESGYGDYSKAWDY
                     IAERLTEFGTILTYNRAGLGKSGKSSKQRISSEMVKDLRTCLNLLQLKPPYIFVGHSFG
                     GINARLFTVFYPEDMLGTVLVDSTPENYKELFLPIMSPGFQEAYYKQFAYESSYEEFMF
                     SLAEADRHCKSMNDIPLVVLAAGKKAFYSQAAQLKWLQLQRELLQLSSKSKFIIAEHSG
                     HYIQKDEPHYIIGAVKWILGVGER"
     aSDomain        complement(2726..3043)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CON62_RS27125_Abhydrolase_1.1"
                     /evalue="1.40E-13"
                     /label="CON62_RS27125_Abhydrolase_1.1"
                     /locus_tag="CON62_RS27125"
                     /protein_end="133"
                     /protein_start="27"
                     /score="43.0"
                     /tool="antismash"
                     /translation="PVIIMESGYGDYSKAWDYIAERLTEFGTILTYNRAGLGKSGKSSK
                     QRISSEMVKDLRTCLNLLQLKPPYIFVGHSFGGINARLFTVFYPEDMLGTVLVDSTPEN
                     YK"
     CDS_motif       complement(2807..2842)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CON62_RS27125_0001"
                     /evalue="6.50E-05"
                     /label="NRPS-te1"
                     /locus_tag="CON62_RS27125"
                     /protein_end="106"
                     /protein_start="94"
                     /score="15.5"
                     /tool="antismash"
                     /translation="PYIFVGHSFGGI"
     gene            complement(3117..3677)
                     /locus_tag="CON62_RS27130"
                     /old_locus_tag="CON62_27135"
     CDS             complement(3117..3677)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002127500.1"
                     /locus_tag="CON62_RS27130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27135"
                     /product="hypothetical protein"
                     /protein_id="WP_001080627.1"
                     /transl_table=11
                     /translation="MNRKTIVITIAAVSGGGKTTITESLTHELTNSKALFFDSYNFDNC
                     PADICKWIDDGANYDEWVLTPLIHDIQHLIRDSKLDYIIVDYPFAYLNREMGQFIDVTI
                     FIDTPLDIAMARRILRDFKEDTMSEIHNDLKHYMAHARKAYLEAIHTVKPNSDIVLDGS
                     FSVSEIIDHVVEELDRREVIVNG"
     gene            complement(3728..4267)
                     /locus_tag="CON62_RS27135"
                     /old_locus_tag="CON62_27140"
     CDS             complement(3728..4267)
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002065535.1"
                     /locus_tag="CON62_RS27135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27140"
                     /product="GNAT family protein"
                     /protein_id="WP_073990635.1"
                     /transl_table=11
                     /translation="MMYERRMRVIKLVPFKRSDFKQLINWIHSEQFLIQWSGNAFTYPL
                     NEQQLEKYIESANTLAFKVIDEKTEEVLGHISLGQIDDINKSARIGKVLVGNTKMRGRS
                     IGKHMMKAVLHIAFEELKLHRVTLGVYDFNTSAISCYEKIGFVKEGLLRDSKKVGETYW
                     NLWEMSMLEYEWNNKK"
     gene            complement(4371..4727)
                     /locus_tag="CON62_RS27140"
                     /old_locus_tag="CON62_27145"
     CDS             complement(4371..4727)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000535569.1"
                     /locus_tag="CON62_RS27140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27145"
                     /product="hypothetical protein"
                     /protein_id="WP_000535569.1"
                     /transl_table=11
                     /translation="MGSRFNNCKKKCTCKQDDCWEIFEECKKEKHEKCDNSCVQGIRDE
                     LKKLINRTVQINTEGRTYVGTVASVSCDVVKLAAIPGSVAVIISICKIEAIFPPVTTIT
                     AEFDFNGVDVANKA"
     gene            5305..5514
                     /locus_tag="CON62_RS27150"
                     /old_locus_tag="CON62_27155"
     CDS             5305..5514
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CON62_RS27150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CON62_27155"
                     /product="hypothetical protein"
                     /protein_id="WP_002043484.1"
                     /transl_table=11
                     /translation="MTGGSLKKSIIVMMIGVLRKSIVMMIGGNLKKSIIVMMIGVLNEI
                     SVVVNVSLFVVIVKENIGKILMST"
     gene            complement(6068..6529)
                     /locus_tag="CON62_RS27160"
                     /old_locus_tag="CON62_27165"
     CDS             complement(6068..6529)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569864.1"
                     /locus_tag="CON62_RS27160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27165"
                     /product="hypothetical protein"
                     /protein_id="WP_000569863.1"
                     /transl_table=11
                     /translation="MIEIKSMIYSYKLKRRIAKDLYGSRDELTMLLNEFNNMKSKLKSD
                     KKKNNMLSRLQLMYQNMKLDKQYSLPFALNSRLLERLEDESIQTTEECVSCLHVMLEIN
                     YEKIQHYGSNTSRSFVPLSQSSICLADFVCLTGFVLLGLLGTITFGGIM"
     misc_feature    complement(6688..6701)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.37"
                     /tool="antismash"
     misc_feature    6864..6877
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     strong, score: 26.74"
                     /tool="antismash"
     gene            complement(6921..7301)
                     /locus_tag="CON62_RS27165"
                     /old_locus_tag="CON62_27170"
     CDS             complement(6921..7301)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450238.1"
                     /locus_tag="CON62_RS27165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27170"
                     /product="hypothetical protein"
                     /protein_id="WP_000450239.1"
                     /transl_table=11
                     /translation="METSTFLGLFWGWITVIVSGILFVRPSVLRELKKLVVEDRGFGIM
                     YGFLSIFLGLGTVILHNVWAFNWQGFLTVIAWLALLKGIYIIAYPEPSKKTDFELRILS
                     TRIALAIIGALALWMLIVIYIK"
     gene            7937..8305
                     /locus_tag="CON62_RS27170"
                     /old_locus_tag="CON62_27175"
     CDS             7937..8305
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002189674.1"
                     /locus_tag="CON62_RS27170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27175"
                     /product="septum formation initiator family protein"
                     /protein_id="WP_000526889.1"
                     /transl_table=11
                     /translation="MGNIPKVSSHQSSPNIPSQQVNPNTQQGNRKKTRRRIITTLAIMV
                     PIIFVLQYSLNNQQEMIKEKQITLNTEQQKLSSVKKDGHSLKNDVKALTSSEEEILKFA
                     RKLYGFSKPNETIFQITE"
     gene            8503..>8559
                     /locus_tag="CON62_RS32650"
                     /pseudo=""
     CDS             8503..>8559
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03720.3"
                     /locus_tag="CON62_RS32650"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="exosporium leader peptide"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDEFLSFVAHNPGSIGPTL"
     gene            complement(8577..8789)
                     /locus_tag="CON62_RS32655"
     CDS             complement(8577..8789)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254010.1"
                     /locus_tag="CON62_RS32655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_240522372.1"
                     /transl_table=11
                     /translation="MVSLEVKVIDAGPAGRLNPVGPVGPVGPVGPVGPVGPVGPVGPVG
                     PVDPVDPVGPVEPVAPVEPVGPVGN"
     misc_feature    complement(8798..8815)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 23.05"
                     /tool="antismash"
     gene            complement(8805..9050)
                     /locus_tag="CON62_RS32660"
     CDS             complement(8805..9050)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016081561.1"
                     /locus_tag="CON62_RS32660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_000237381.1"
                     /transl_table=11
                     /translation="MVIVTLAIVPGESRSEAVTVTVPGPLAARNTAVKLPEALVMTARG
                     TMKAREGLLNEKLTTTPGVGLPFTNTCPEKNKVLFP"
     gene            9368..9535
                     /locus_tag="CON62_RS32230"
     CDS             9368..9535
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358201.1"
                     /locus_tag="CON62_RS32230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_000358199.1"
                     /transl_table=11
                     /translation="MDKKDLLSQQLDHVSSDALNTPSKAQEQMQETSQKAHNSNKKGNT
                     QSLHVEDLPN"
     gene            complement(10001..11941)
                     /locus_tag="CON62_RS27185"
                     /old_locus_tag="CON62_27190"
     CDS             complement(10001..11941)
                     /NRPS_PKS="Domain: AMP-binding (97-521). E-value: 3.8e-82.
                     Score: 268.0. Matches aSDomain:
                     nrpspksdomains_CON62_RS27185_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017560287.1"
                     /locus_tag="CON62_RS27185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27190"
                     /product="AMP-binding protein"
                     /protein_id="WP_000806475.1"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-88, bitscore:
                     290.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQAVWFPTEEYKEKTRLYGWMKSLGYEDYETFYNKSIEETAWFW
                     GEAEKAVGYQWMKPYTEVLDLENGTPFAQWYNDGTCNVVESALSRWIADEVTRKQPALQ
                     YEGENGTSKSFTYEELDNWVSRVANGLKQAGIEKGDRVTIYMPMIPETVVAMLAVMKIG
                     AIISPIFSGFASDAVMTRVQAAGSKMIITADGFSRRGKIVSLKDEVDKACEHCPTVEKV
                     VIVRHAGNNFTPHHYDFSWSTLEKEKPFIHAEEMHSDDPLMLIYTSGTTGKPKGTVHTH
                     AGFPLKAAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLLFGSLINGATMVMYEGVPDFPE
                     ADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHSLKSLEVFASTGEPWNPDPWMW
                     LFETVGKGKVPICNYSGGTEISGGIFGNVLIKPIAPISFNASLPGMAAVVLDDQGKPIR
                     DEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKWVHGDWVIYDGEQYIITGRSDD
                     TLNIAGKRIGPAEYESILVKHINVIEAASIGVPDDVKGEVCHCFVVLRDGVIFTAELKK
                     ELMSLVNSHIGKALCPKDIHVVADLPKTRNSKVMRRVIKAAYLGKELGDLSSLVNPEVV
                     PHIQGLQSSKL"
     CDS_motif       complement(10346..10408)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CON62_RS27185_0002"
                     /evalue="7.80E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="CON62_RS27185"
                     /protein_end="532"
                     /protein_start="511"
                     /score="12.3"
                     /tool="antismash"
                     /translation="TGRSDDTLNIAGKRIGPAEYE"
     aSDomain        complement(10379..11650)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CON62_RS27185_AMP-binding.1"
                     /evalue="3.80E-82"
                     /label="CON62_RS27185_AMP-binding.1"
                     /locus_tag="CON62_RS27185"
                     /protein_end="521"
                     /protein_start="97"
                     /score="268.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RKQPALQYEGENGTSKSFTYEELDNWVSRVANGLKQAGIEKGDRV
                     TIYMPMIPETVVAMLAVMKIGAIISPIFSGFASDAVMTRVQAAGSKMIITADGFSRRGK
                     IVSLKDEVDKACEHCPTVEKVVIVRHAGNNFTPHHYDFSWSTLEKEKPFIHAEEMHSDD
                     PLMLIYTSGTTGKPKGTVHTHAGFPLKAAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLL
                     FGSLINGATMVMYEGVPDFPEADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHS
                     LKSLEVFASTGEPWNPDPWMWLFETVGKGKVPICNYSGGTEISGGIFGNVLIKPIAPIS
                     FNASLPGMAAVVLDDQGKPIRDEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKW
                     VHGDWVIYDGEQYIITGRSDDTLNI"
     CDS_motif       complement(11099..11155)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CON62_RS27185_0001"
                     /evalue="7.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="CON62_RS27185"
                     /protein_end="281"
                     /protein_start="262"
                     /score="24.7"
                     /tool="antismash"
                     /translation="MLIYTSGTTGKPKGTVHTH"
     gene            complement(11991..13532)
                     /locus_tag="CON62_RS27190"
                     /old_locus_tag="CON62_27195"
     CDS             complement(11991..13532)
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012094296.1"
                     /locus_tag="CON62_RS27190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27195"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_000893092.1"
                     /transl_table=11
                     /translation="MLEQKQQSNNFEERVETIKQGGAPKYHEQNKAKGKLFVRDRLALL
                     FDNGEYVEDALFANCEQTGLPADGVVTATGKIHGRTACVMANDSTVKAGSWGARTVEKI
                     LRIQETAEKLRVPLFYLVDSAGARITDQVEMFPGRRGAGRIFYNQVKLSGKVPQICLLF
                     GPSAAGGAYIPAFCDVVMMVEGNASMYLGSPRMAEMVIGEKVTLEEMGGARMHCSVSGC
                     GDVLCKTEEDAITQARQYISYFPSNYLEKTPLMTPQEPKQFDKTLEQIIPENQNAPFNM
                     KDLINRIIDDGSFFEVKKLFAQELITGLARIDGKPIGIIANQPRMKGGVLFHDSADKAA
                     KFINLCDAYHIPLLFLADVPGFMIGTKVERAGIIRHGAKMISAMSEATVPKISIIVRKA
                     YGAGLYAMAGPAFEPDCCLALPTASIAVMGPEAAVNAVYANKIAALPEEERASFIAEKR
                     EEYKKDIDIYHLASEMVIDGIVHPNNLREELKGRFEMYMSKYQVFTDRKHPVYPV"
     gene            complement(13535..14323)
                     /locus_tag="CON62_RS27195"
                     /old_locus_tag="CON62_27200"
     CDS             complement(13535..14323)
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (14-254). E-value: 5e-74. Score:
                     240.6. Matches aSDomain:
                     nrpspksdomains_CON62_RS27195_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001990763.1"
                     /locus_tag="CON62_RS27195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27200"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_000939821.1"
                     /transl_table=11
                     /translation="MLQLQNISVDYVTPHVVKISLYRERQANSLSLALLEELQTILTEI
                     SEESNTRVVILTGAGEKAFCAGADLKERAGMNEEQVGHAVGMIRTTMEMVEQLPQPVIA
                     AINGIALGGGTELSLACDFRIASENASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKEL
                     IYTGRRISAQEAKEYGLVEFVVPADLLEEKAIEIANQIASNGPIAVRLAKEAISNGVQV
                     DLHTGLQMEKQAYEGVIHTEDRLEGLQAFKEKRKPMYKGE"
     aSDomain        complement(13562..14281)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CON62_RS27195_ECH.1"
                     /evalue="5.00E-74"
                     /label="CON62_RS27195_ECH.1"
                     /locus_tag="CON62_RS27195"
                     /protein_end="254"
                     /protein_start="14"
                     /score="240.6"
                     /tool="antismash"
                     /translation="HVVKISLYRERQANSLSLALLEELQTILTEISEESNTRVVILTGA
                     GEKAFCAGADLKERAGMNEEQVGHAVGMIRTTMEMVEQLPQPVIAAINGIALGGGTELS
                     LACDFRIASENASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKE
                     YGLVEFVVPADLLEEKAIEIANQIASNGPIAVRLAKEAISNGVQVDLHTGLQMEKQAYE
                     GVIHTEDRLEGLQAFKEK"
     gene            complement(14328..15239)
                     /gene="mvaB"
                     /locus_tag="CON62_RS27200"
                     /old_locus_tag="CON62_27205"
     CDS             complement(14328..15239)
                     /EC_number="4.1.3.4"
                     /codon_start=1
                     /gene="mvaB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017149491.1"
                     /locus_tag="CON62_RS27200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27205"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_000775419.1"
                     /sec_met_domain="HMGL-like (E-value: 2e-50, bitscore:
                     164.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPNFAVIKEVGPRDGLQNEKKIVGTKDKVKWIQLLTEAGLSYV
                     EVSSFVHPKWVPALADANDVFSELKRDPNVTYAALVPNQNGLERAFLQNVDEVNVFLSA
                     SESHNKSNINKSIKEALTVIEDITKQAIFEGKKVRGYVSTVFGCPYEGDISAAAVDEIC
                     NQLFSYGIYEVSLGDTIGVANPLQVEQVLEHLLKKYDASQFAMHFHNTYGMALANVVKS
                     LEHGITTFDSSCGGLGGCPYAPGASGNVATDDLVHMLHKLGVQTNIDEEKLWRASQFIQ
                     SKLNIQLPSHVYRALQHKTISR"
     gene            complement(15261..15476)
                     /locus_tag="CON62_RS27205"
                     /old_locus_tag="CON62_27210"
     CDS             complement(15261..15476)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001987345.1"
                     /locus_tag="CON62_RS27205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27210"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="WP_001987345.1"
                     /transl_table=11
                     /translation="MMTKVYASMAGNVWKIVVGVGDTVEEEQDVVILESMKMEIPIISE
                     EAGTVMKINVQEGDFVNEGDVLLEIE"
     misc_feature    complement(15500..15516)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 25.24"
                     /tool="antismash"
     gene            complement(15503..16840)
                     /locus_tag="CON62_RS27210"
                     /old_locus_tag="CON62_27215"
     CDS             complement(15503..16840)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000486723.1"
                     /locus_tag="CON62_RS27210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27215"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_000486760.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 5.8e-12,
                     bitscore: 38.4, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 7.7e-08, bitscore:
                     25.4, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 6.3e-08, bitscore: 25.3,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1e-10, bitscore: 34.3,
                     seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQKILIANRGEIAVRIMKTCQKLGIRTVAIYSEADENALHVKMA
                     NEAYLVGGPRVQESYLNLEKIIEIAKKTNVEAIHPGYGLLSENPSFPIRCKEEGIVFIG
                     PSEEIITKMGSKIESRIAMQAADVPVVPGITTNIETAEEAIEIAKQIGYPLMLKASAGG
                     GGIGMQLMETEQTLTKAFESNKTRAQNFFGNGEMYLERYIADAHHIEIQLLADTHGNTV
                     YLWERECSVQRRNQKVIEEAPSPFLDEGTRKAMGEVAVQAAKALGYTNAGTVEFLVDDQ
                     KNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLLIASGEKLSFTQDDVKRSGHAIEARIY
                     AEDPKTFFPSPGKITDLTLPSNIRMDHFLENHVTITPFYDPMIAKVIAHGETREEAISK
                     LENALEELKIEGIKTNTPMLLQVLGDDVFKSGIYTTGFVTKQLVKK"
     gene            complement(16856..18001)
                     /locus_tag="CON62_RS27215"
                     /old_locus_tag="CON62_27220"
     CDS             complement(16856..18001)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001980414.1"
                     /locus_tag="CON62_RS27215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27220"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_000397277.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3.9e-41, bitscore:
                     133.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.3e-27, bitscore:
                     88.8, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.2e-58, bitscore:
                     189.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFTLTREKQMIKEMVRDFAEKEIAPKAVYYDKTAEFPYETFQKM
                     GELGLLGIPFPEEYGGSGGDTVSYALAVEEIGRACGGTGLSYAATISLGASPIYYFGTE
                     EQKQKYLVPMASGKTLGAFGLTEPNAGSDAGGTQTKAVLDGDEYVISGEKCWITNAEYA
                     NTIIVTAINGVEENGRKRISAFIVPTTSEGLTISSPYDKMGVRASNTCEIVLDGVRVPK
                     ENILGDVNKGFKQFLYTLDGGRISIAALAVGIAQSAFERALQYAKERQQFGKTISNFQA
                     IQFKLADMATEVELARNLVHKAAWLKDNDKPFGKEAAMAKLFASEAASRIANHAVQIHG
                     GYGYMREYEVERHIRDAKLLEIGEGTSEIQRLVIARHLGCR"
     gene            complement(18218..19186)
                     /locus_tag="CON62_RS27220"
                     /old_locus_tag="CON62_27225"
     CDS             complement(18218..19186)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248633.1"
                     /locus_tag="CON62_RS27220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27225"
                     /product="DUF523 and DUF1722 domain-containing protein"
                     /protein_id="WP_001248628.1"
                     /transl_table=11
                     /translation="MRQFAKPTIVVSKCLEFDACRYNGEMIPDVTIRNLQPFVTFIPVC
                     PEVEIGLGIPRETIRIVEENGVNTLVQPSTREDVTEKMEQFSNGFLQTISDVDGFILKN
                     RSPSCGTRDVKIYSGFEKAPAKGKGPGLFGGAVLKNFSHLPIEEEGRLSNFIIREHFFT
                     RLFTIAYYKMIKHNKNMKDLVSFQSDNKYLFMAYNQVKQKELGRIIANQKNETIEIVFD
                     NYEKTLYELFLRAPRYTSNVNVCEHIFGYFKTKLKKQEKDYFLELIQKYAEKKIPLSSL
                     LAILKSWAIRFDEKYLLGQTYFEPYPEALVEISDSGKGRDY"
     gene            complement(19191..19844)
                     /locus_tag="CON62_RS27225"
                     /old_locus_tag="CON62_27230"
     CDS             complement(19191..19844)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002161720.1"
                     /locus_tag="CON62_RS27225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27230"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_000711180.1"
                     /transl_table=11
                     /translation="MKKDWLEELIAATNTDNRNERQMRILEAAVDMFGEKGYASTSTSE
                     IAKRAGVAEGTIFRYYKTKKDLLLAVVMPTLTKFAAPFFVQAFAKEIFKTDYESYEGLL
                     RVVIHNRFEFAKKHFPMIKILIQEVPFQPELKSEIQQLVETELLSHFKKLIVKFQEEGG
                     IIEMPPPSVLRLTLSAVLGFLLTRFLLLPEENWDDELEIENTIQFILYGLTPRR"
     gene            complement(19869..20888)
                     /locus_tag="CON62_RS27230"
                     /old_locus_tag="CON62_27235"
     CDS             complement(19869..20888)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002161721.1"
                     /locus_tag="CON62_RS27230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27235"
                     /product="ABC transporter permease"
                     /protein_id="WP_001265602.1"
                     /transl_table=11
                     /translation="MRVNGVIIRIIRQFFRDKRSLAMMFGAPMLLLWLLSLVFTQKDYK
                     PHIAVVDVPASIVKVMKNQEASIYEYSKKKAISELEKQKIDAVIHLENGKINLLLEGSD
                     SSKNRAVLQVLQKSTEKNDVSIMKPEVNYLHGSKDFTMFDGLGPVLIGFFTFFFVFILS
                     GVSFVRERLSGTLERLLSTPVRRWEIVVGYIIGFGIFAFIQSVIIVSFSVYVLDLYVAG
                     SIWLTLLITCMLSLTALTLGTFLSAYANNEFQMIQFIPLVIVPQIFFSGLFPIESMNKW
                     LQMLGKLFPLTYGADAMRQVMIRNQGFTEIALDLTVLLLFSLLFAVGNVFALKKHRKI"
     gene            complement(20885..21610)
                     /locus_tag="CON62_RS27235"
                     /old_locus_tag="CON62_27240"
     CDS             complement(20885..21610)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016108448.1"
                     /locus_tag="CON62_RS27235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27240"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_001171599.1"
                     /transl_table=11
                     /translation="MQKPSIVLQNVSKSFGKKEVLHDLSLQIEKAEIFGLVGPSGSGKT
                     TLIKLIAGINQASKGDVFVYNINMPNLNEMKRIGYMAQADALYEELSAYENADFIATMY
                     GLKGKHKKERIKEVFDLVQLSQHMKKQVQHFSGGMKKRLSLAIALLHEPEILILDEPTV
                     GIDPLLRKTIWGKFYELKKKGTTIIVTTHIMDEAEFCERLGLIREGNLVAVGTPEELKK
                     RVSSGRIEDVFLLEEGVES"
     gene            complement(21797..22048)
                     /locus_tag="CON62_RS27240"
                     /old_locus_tag="CON62_27245"
     CDS             complement(21797..22048)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548597.1"
                     /locus_tag="CON62_RS27240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27245"
                     /product="hypothetical protein"
                     /protein_id="WP_000548627.1"
                     /transl_table=11
                     /translation="MHKEYEIEEYTAIEEQIHYYCQCLLVSHPEQIIKYLEKRLEKYAE
                     TLQYAHLYPDTVILPLQQLVIEYSLDLARIRKYMNLET"
     gene            complement(22265..23107)
                     /locus_tag="CON62_RS27245"
                     /old_locus_tag="CON62_27250"
     CDS             complement(22265..23107)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002141840.1"
                     /locus_tag="CON62_RS27245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27250"
                     /product="metallophosphoesterase"
                     /protein_id="WP_001036669.1"
                     /sec_met_domain="Metallophos_2 (E-value: 3.1e-10, bitscore:
                     33.3, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKTKRIILLIGTIVGICIFLYLQNNLISITEVKITSSKIPSAF
                     KGYKILQISDLHNKKFGDNQDILIQKVKSINPDIIAITGDLIDSKSYDEEISMQVIREL
                     VKEYPVYFVTGNHEKWSGKYNSLEKELKKNHVTVLRNEHVIIQKGGQEINLLGIDDPEF
                     NNRDINEGSIVKDAIVKAKIETQPNRYNVLLSHRPEFIEEYAEERIDLVFSGHAHGGQV
                     RLPFISGLVAPNQGVLPKYTAGLYEEQNTSMVVSRGLGNSIIPQRILNRPEIVVAQLN"
     misc_feature    23427..23440
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.21"
                     /tool="antismash"
     gene            23766..24335
                     /locus_tag="CON62_RS27250"
                     /old_locus_tag="CON62_27255"
     CDS             23766..24335
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782792.1"
                     /locus_tag="CON62_RS27250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CON62_27255"
                     /product="hypothetical protein"
                     /protein_id="WP_000782800.1"
                     /transl_table=11
                     /translation="MKMKRKIMMTTALAATLATGALPTTSVFAAEKEAPIQQKEAQVSI
                     QPFAQNNLETAVNAALNGPEVKKIKVFEHEFNVKEIEVVNLGAGKKYVKGQISHHLSFR
                     PDDQFYYEFTVQDGKVIDKPVFNIDRGGWTPFAAPLLSILAAYNGIPVNPNDLNALGQQ
                     LGKVIDGSWEHAAQSIATVVSLSFNE"
ORIGIN
        1 attacaaatg tatcacatga tttacgtact ccccttacat caatagttgg atacgtgaat
       61 ttaatccatc atgataatta tagagatgaa gtggaattac gtcattacat acaagtcatt
      121 tatggtaaag taacacgtct aaatgcatta atgaatgact tgtttgaata cacccgtgtt
      181 caaaataaag agttaagttt atattctgct cccattgata ttgtagagct acttggacaa
      241 ttaactgttc aattccgaat acaagtgcaa gaagcaaata ttcaatgccg tccttctttc
      301 ccctctcaaa aactcatggt attagctgat ggagacaaat tagtgcgtgt atttgaaaat
      361 cttattataa acgctatcgc ttatggaaac gaaggtggtt atattgacct taccgcttat
      421 gaaagcaata atatgattac aattgatata acaaattacg gacaacctat tcctagtaca
      481 gatttacctc atatttttga acgtttttat cgtgttgaaa aatcacgttc aacaaacact
      541 ggtggatcag gactcggatt agcaattgca aaaagtattg tcgaactgca taaaggaacg
      601 attgaagtat atagtgatga caagaaaaca actttcactg taaaactact accatataaa
      661 aattaataca ccataatttt aggttcaatt tctaatatga taagaaattg aaccttttat
      721 tttccatcaa tatccaaagt ttaataatct tttataattc tttagaaatt ctttaccttt
      781 tctttcttcc taattaagca ttccttttta caatattatt attgatgtca tagtaggagg
      841 atcgcttatg caattcttga aaaaattcac aattttatta ttatctttta ttattactgc
      901 acttatcgtt ttatattttt atctttatgt aaatggtcca attattcaag ctaaatcagc
      961 tattttaata gatgctaatt caggtgaagt tatttataaa aaaaatgaag aaacccctat
     1021 acaatcagct actttgtcta aattaatgac agagtatatc gtattggaac aactaaatga
     1081 cggcaaaata cagttagatg aatccgtaaa aataagtaac gaattattcc aagcggaaac
     1141 gactcctatg caagtaacaa caaaggataa aacgacggtt cgtgatttac ttcatgcatt
     1201 gcttttaaca ggaaataatc gttctgcact cgcactggca gaacacattg gtggcaatga
     1261 agataacttt acaacgttaa tgaatgaaaa agcaaaacag ctacagttat cacagccatc
     1321 tccttttcta aactctactg gagctaatca agatacaaat aaacaatcga atacaacagc
     1381 gaaagatgca gctaaactag caacgcattt agtaaaagat tttcctaatg tactgaatat
     1441 gacgaaacta acctcttacc aatttacctt caaaaatttt caagttttca acacaaataa
     1501 aatgatttat tccctcaatg aaaacattaa attccaaggt gttgatggct tgcaaactag
     1561 tttttcaact aacggtaata atagttttgt cggtactgca aaactaggag atactaggct
     1621 tatttcagta atattagaat ccgatgaaga aaacactact tttattgaaa caaaaaaatt
     1681 acttcagtac ggttttgaac cttcctcgta ctctgcactc caagctttta aagatactct
     1741 tacatcttgg gcaatattgc tacagtttaa aaatttaatc atacaaacga tgatgatctt
     1801 tttcattatt acaattttaa tgtttttaca tttacgtcaa agaaaatccg aggatttcaa
     1861 ctaagaaatc ttcttacata taaaaaccga cttgcgttta cagtacaagt cggtttttac
     1921 gtctataatc ctcttccaat taaattcgct gaaacgggct gaagatttaa ctctcttgcc
     1981 catattgata gctgacctat atgatgaatt tcatgtacga caacatgtcg taacacttca
     2041 ccatacttgt actctttatc cgtccatgaa acttttaata ttttattctc taagtcttct
     2101 gtccacgatt gtaaaaatcc ctctaaatcc ttattataca aatgagataa tgctttcact
     2161 ttttgaatag attgataatc cttaaattgc ggctcatcta cttcttttcc tttcaaatca
     2221 caaatccagc tatactcaac atctacaata tgaaataatg tttctaatat acttccaaca
     2281 ccaccaacac gtttgctaag taattcttcc actgtaagtt gttcacacca cttaaaccaa
     2341 tcttctctta cttgccagtt atattgaaat acagtgtaca catttatctc tcccctaccc
     2401 caagtatcca cttaacagca cctataatat aatgtggctc atccttttga atatagtgac
     2461 cgctatgttc tgcaattata aatttacttt tactggataa ttgtaataat tctctttgta
     2521 attgtaacca tttcagttgt gcagcttgcg aataaaaagc ttttttacca gcagctagca
     2581 cgacaagggg aatatcgttc attgatttac aatgtctatc tgcttcagct agactaaaca
     2641 taaactcttc atatgaactt tcatatgcaa attgtttata gtaagcttct tgaaatcctg
     2701 gagacatgat tggcaaaaat aattctttat aattttctgg tgtcgaatca accaaaactg
     2761 ttcccaacat atcctcggga taaaaaaccg taaataaccg tgcatttata ccaccaaaag
     2821 aatgccctac aaaaatataa ggtggcttca gttgtaaaag atttaaacat gttcttaaat
     2881 ctttgaccat ttcagaacta atacgttgct tggaactctt cccacttttc cctaatccag
     2941 ctcgattata tgtaagtatc gtcccaaatt ccgtcagtct ttcagcaata taatcccatg
     3001 cctttgaata atccccgtag cctgattcca ttataataac aggctgccgc ttttttcctt
     3061 gaaatacttt cgtatacatt ttaaaatcat caacttgtac atattcctct atacatttaa
     3121 ccattgacaa tcacttctct tcggtcaagt tcctcaacaa catgatcaat tatttcactt
     3181 acagaaaaag atccatccaa tacgatatct gaattcggtt taacagtatg aattgcctct
     3241 aaataagctt ttctcgcatg tgccatgtaa tgttttaaat cattatgtat ttcactcata
     3301 gtatcttctt taaaatctcg taaaattctt ctagccattg caatatctaa aggtgtgtca
     3361 ataaatatag ttacatcaat gaactgcccc atttctctat ttaagtatgc aaaaggataa
     3421 tctacaataa tatagtctaa tttactatct cgtataagat gctgaatatc atgaattaat
     3481 ggtgtaagta cccactcgtc ataattcgct ccatcatcaa tccatttaca aatatcagca
     3541 ggacagttat caaagttata actatcaaaa aatagcgctt ttgaatttgt taactcatga
     3601 gttaaacttt ctgtaatagt agttttacct ccccctgaaa cagctgcaat tgtgattact
     3661 atagtctttc tattcataat ttcccaccaa tcccttttaa ttaacataat aaaattataa
     3721 gaaactatta ttttttatta ttccattcat attctagcat actcatttcc cataaattcc
     3781 aatacgtttc tcctactttt tttgaatctc ttaataaacc ttcttttaca aatcctattt
     3841 tttcataaca agaaatggcc gacgtattaa aatcatacac gccaagagtt actctatgta
     3901 gttttaattc ttcaaacgca atatgaagta ctgctttcat catatgtttt cctattgaac
     3961 gccctctcat tttcgtatta ccaactaaca cttttccaat tctcgcagac ttatttatat
     4021 cgtctatttg accaagtgaa atatgaccaa gtacttcttc agtcttttca tctattactt
     4081 tgaaagcgag tgtatttgca ctttctatat atttctctaa ttgctgttcg tttaaaggat
     4141 atgtaaatgc atttcctgac cactgtatta aaaattgttc ggaatgaatc caatttatta
     4201 attgtttgaa atcagatctt ttaaagggca ctaatttaat cactctcatt ctcctttcgt
     4261 acatcactct ttatagcctc aaacttattt ctatataaag aatatattct ccttttatac
     4321 gaaattaaaa taaagccatt catcagaatg gctttacaaa caaagcataa ttatgcttta
     4381 tttgctacgt caacaccatt aaaatcaaac tctgcagtaa tcgttgtaac aggagggaaa
     4441 attgcttcaa ttttgcaaat ggagataatt actgcaacag atccaggaat agctgcaagc
     4501 ttaactacat cgcaacttac agacgcaaca gtacctacat aagtacgtcc ctctgtatta
     4561 atttgaactg ttcgattaat taatttctta agctcatctc taattccttg tacacaagaa
     4621 ttatcacatt tctcatgctt ttccttttta cactcttcga atatctccca acaatcatcc
     4681 tgtttacatg tacatttctt tttacaatta ttaaatcgag aacccaaaac ctcaccccct
     4741 aatcctttct attagtaaag tatgtccact agcttaaaag tgtacgaggc aaacacatag
     4801 aaagaaaaaa acaaacaatt gtactaaaca tttttttctt tattaattat aaaaacaatt
     4861 ctttaacagt tagcggcttg tttagtgagg ggacttggat ttaattctgc tgaatttaaa
     4921 gtttagataa cctctttatc aaaagaatct ttttttcttt taataagcca gcccctttaa
     4981 gagttagctg ttttgaaata tacattcaga aaaacgtact ccaaaataag atattattta
     5041 taatcagaat gttttcttca acatgtgttt attgataaat gtcataacca gtaattctct
     5101 ccactatctc ttggaaatta gcatagtttt tatgaattct atatgtagta gaaagcactc
     5161 tatcatataa aggtaaaata ataggtttat aaacaagcca tttcttcact aaaacataga
     5221 atgatagtaa tcctattgaa gggaggtata aaaaaatgtc ttggaataat gattgctgga
     5281 gttctaagaa acagcattgt tgtgatgact ggtggaagtc taaagaaaag catcattgtg
     5341 atgatgattg gagttctaag gaaaagcatt gtaatgatga ttggtggaaa tctaaagaaa
     5401 agcatcattg tgatgatgat tggagttcta aacgaaataa gtgtcgttgt aaatgtttct
     5461 ttatttgttg tcattgtaaa agaaaacatt ggtaagattt taatgtcaac ttaacggaaa
     5521 gaatatgtct tttgggatcg ataaatacta gaatataata tacaaaaagc tgactgagta
     5581 tagtcggctt tttgtatatt aacacataaa gatttatact gccatctata gttacaagtt
     5641 gagtggagtg tcgaaatata agctgactct tataaatcga ctttgtaatt atttcacata
     5701 cactttattt acagtagtaa gttttccttt tgttattgat gcaaaattaa gtcctgtaac
     5761 acttgatttt gcatcaataa caaaccctca gcatactcac ttaatcgctg cgacaacata
     5821 gggtttatca tttcacgttt attatgagtt acccatatct tatattttgt gtaactagcc
     5881 caaacgctaa attccttgtt attcatagca tcataacatt ttatctttct agttacacaa
     5941 tgcattaaca atgagcaact agaaattagc atccgtgtca ttcttccctg tctatcgcat
     6001 gagctcttct atgtaactaa aaaatacacc ttaaatgggt ggtcttttat gtaagtgaat
     6061 aaaaagatta cattatccct ccaaatgtaa ttgttcctag taagcctaat aaaacaaatc
     6121 ctgtcaaaca aacaaaatca gcaagacaaa tggaagactg tgataaagga acaaatgacc
     6181 tacttgtatt agatccataa tgttgtattt tctcataatt tatttctaac attacgtgta
     6241 gacatgatac acattcttca gttgtttgaa tagattcatc ttctaatcgc tccaataacc
     6301 tactattaag agcaaacgga agagaatact gcttgtctaa tttcatattt tggtacatta
     6361 attgtaaacg agataacata ttatttttct ttttgtcaga cttcagttta cttttcatat
     6421 tattaaattc atttaataac atcgtcaact catctctgct gccatataaa tctttagcta
     6481 ttcttctttt tagtttgtac gaataaatca tagatttaat ctcaatcatt gtattacact
     6541 tcctaattaa attttattta acccaatatg ttaaaaacag tactttcaaa tcctattaaa
     6601 aatacactta agtatcttga tttactatcg attaatatta cattaacctt acacagttgt
     6661 aataatttct ttaacacccc tcccgaacaa acatacattt ctttccgctc agttttaatt
     6721 cggaagttaa ttgcgtcatt tataaaaata accctgatct attttgttaa taaaaaataa
     6781 aaaagtggcc accaaactac agagtaatat aacaactccc tttttagttt gatgtccacg
     6841 gattcttcca gtaggactaa atttataatt attattatag ccttttctca tattttagta
     6901 tatttctcat tagaaaaaga ttattttata tagattacta taagcatcca taaagccaag
     6961 gcgccaatga tagcgagcgc tatacgtgta gatagtatcc ttaattcaaa atcagttttc
     7021 ttggagggtt caggatatgc aattatgtaa attcccttta ataatgcaag ccatgcaata
     7081 accgttagga acccctgcca gttgaatgcc catacattat gtaagattac agtacctagc
     7141 cctaggaaaa tcgataaaaa accgtacata ataccaaacc ctctgtcttc aaccactaat
     7201 tttttcaatt cacgtaatac cgatgggcgt acgaaaagta ttcccgatac gataaccgtg
     7261 atccatcccc aaaacaatcc taaaaaagtg ctagtttcca tttttagttc actcccctca
     7321 attatttata tttcagatat tcctaccttt agaacaattt cagcacctat atattggcta
     7381 tattctgctc tttattcata caaatatggc atattcaata cctatcctta atcatctcat
     7441 tcttcgtcat tatctatccg aatcaaccga agtcgcttta tactattccc gcacactttt
     7501 tcataacttg gagctatcat gcactggagc caatataatg atttatttgc cttttcacta
     7561 acctctacaa ttgtcccctc tgtaataaaa tgatcacctt gatacaatgt atactcgctt
     7621 atcccatgga atcatcatta ttcccttccc tattaaaata gcgtttttat ttcaaatgat
     7681 actcctatta atttaaacgg atttttcagt gtttttaccc aaaaattcgt gatatcgtta
     7741 attagtcgag tacttcatta cttgatgatt atccttagga gcctcgcaga caatcggtgt
     7801 ttcttttatg taaataagga ttttgtttaa actttacgat atgcaactat attaaaatat
     7861 cttctaaaat tcccattaaa catttataat acttttaaac ggtttaaatt ctacaatcag
     7921 taatggaggc attttaatgg gaaacatccc aaaagtatca tcacaccaat caagtcctaa
     7981 tataccctca cagcaagtga accctaatac acaacaaggc aatagaaaaa aaacaagacg
     8041 ccgtattata actactttgg ctattatggt acctataatt tttgtccttc aatattctct
     8101 gaataaccaa caagaaatga ttaaagaaaa acaaatcacg ctgaatacgg aacaacaaaa
     8161 attatcttct gtaaagaagg atggccattc ccttaagaat gatgttaaag ctttaacaag
     8221 tagtgaagaa gaaattttaa aattcgcaag gaaattgtat ggattttcta aaccgaatga
     8281 aactatattt caaataactg aataaaatta cactgcatta cccaaaaggc gatttgaaga
     8341 taatcgcctt tttatattta atttctaaag gaatcatact actctctctt tctatcaaat
     8401 aactattttg tttaatttat taaaatacaa ccgcttgtcc atttcagttt gctctgtcag
     8461 tacatttact aatagtaata caatttttag aggtgataaa ttatggacga gtttttatct
     8521 tttgttgcac ataatcccgg ttctattgga cctacacttc cacctgttca accctttcaa
     8581 ttccctactg gtcccacagg ttctacagga gctactggtt caactggacc aaccggatca
     8641 accggatcaa ccggaccaac tggaccaacc ggaccaaccg gaccaaccgg accaaccgga
     8701 ccaaccggac caaccggacc aaccggacca actggattta atcttcctgc tggacctgca
     8761 tctattacct tgacttctaa cgaaaccaca gcatgtgtat ccactcaagg aaataatact
     8821 ttattttttt cggggcaagt attagtaaac ggtagtccta ctccaggggt agtggtcagt
     8881 ttttcattta gtaacccttc tcttgctttc atggttcctc ttgctgtcat taccaatgct
     8941 tcaggtaact ttaccgctgt atttctagcc gctaatgggc ctggaacagt aaccgttact
     9001 gcttcacttc ttgattctcc tggaacaatg gctagcgtca ctattaccat tgtgaattgt
     9061 ccgtaatggt tttgttttta aggactaagc agtttctgat aagatgagca ctgatttaca
     9121 gtgctctttt ttatcattgg gatgttcttt ttaaatgaaa tttcgtaaca ccctactaaa
     9181 ataatgcttt tattaatcac taatgatctt tatatttctt cagcttgtca tcacaggtaa
     9241 tttttataag tagttaactt atcaatgtag tttgtgtata taattccatt caaagataca
     9301 taatacccac gtaactattt aaaaacactt cgtttttata tcaaagttca aaaaggagct
     9361 acataacatg gataaaaaag atttattaag tcaacaactt gatcatgtat catctgatgc
     9421 gctgaatact cctagtaaag cccaagagca aatgcaagaa acatctcaga aggcacataa
     9481 ttcaaacaaa aagggcaata ctcaatcttt acatgttgaa gatttaccaa attaagacgt
     9541 atatagaata acgaacaaat actaaatttt aaggggaaaa attcttaaga acgagtgaac
     9601 ttaatttttt cccttttcct atttacataa cactttaata ggaaatacgt acacattttt
     9661 gacacattcc ctattacaat ctcctgaaaa ttcgtgataa tattaatttg tcgaatacgc
     9721 caaatttcga catcgcacga caatactatc tcccttagtg aatccctgtc ccccagggat
     9781 ttctcctttt attcattact tttcgcttca ctaaattttc atccttaaca caattcaatc
     9841 aatccaatga atagacacgc cacaatccta ttttgataaa aactataaaa caaacatacg
     9901 tcgtaataat acaagtagaa ttttactact tcaaatttac ttcttctctt tttataaaca
     9961 tgaaaaatga gctccattta catagagctc attcctacat ttataattta ctagactgta
    10021 gaccctgaat atgtggaact acttctggat ttacaagtga tgataaatct cctaattctt
    10081 ttcctaagta agccgctttg atgacgcgtc gcattacttt agaattacgt gtttttggca
    10141 aatccgctac aacgtggata tcctttggac ataatgcttt tccgatatga gaatttacta
    10201 aactcattaa ttctttcttt aattctgctg taaatattac accatctcgt aatactacaa
    10261 agcaatgaca aacctcacct tttacatcgt caggtacacc aatggaagct gcttctatta
    10321 cattaatatg tttcacaaga atagactcat attcagcagg cccaatacgt ttaccagcaa
    10381 tatttagcgt atcatctgaa cgccctgtaa tgatatattg ttcaccatca taaataaccc
    10441 agtcaccatg aacccattta ttttcaaatc gtgaccaata tgtgttcaca taacgctcat
    10501 cgtcttccca gaaacttttc gtcattccaa cccaaggttt ctctaaacat aattctccaa
    10561 cttcatcacg gattggttta ccttgatcat caagtacaac cgcagccata cctggtaacg
    10621 atgcgttaaa actaattggt gcgattggct taatcagaac attaccgaaa atcccaccag
    10681 aaatttcagt tccgcctgaa tagttacaga ttggcacttt tccttttcca actgtttcaa
    10741 acagccacat ccatggatca ggattccaag gctctcctgt tgatgcgaat acttctaaac
    10801 tctttaaaga atgtttattc acatactcat caccttttgc cattaatgca cggattaacg
    10861 ttggcgaaat accgagatga gtaatttcat atttatcaac cgtctcccat aagcgatctg
    10921 cttctggaaa gtctggaaca ccttcgtaca taaccatcgt tgcaccattt atgagtgaac
    10981 cgaataataa aaatggcccc atcatccagc ccatatcagt tacccataat acacgatcac
    11041 cttgtttaat attcattcca aatcctgcat caaaagctgc tttcaaagga aatcctgcat
    11101 gcgtgtgtac cgttcctttc ggcttaccag tcgttcctga tgtatatatg agcattaaag
    11161 gatcatcact atgcatttct tcagcatgta tgaatggttt ttctttttct agcgtactcc
    11221 atgaaaagtc ataatgatgc ggtgtaaaat tatttcctgc atgacgaaca attaccacct
    11281 tttcaacagt cgggcaatgt tcacaagctt tatctacttc atcctttaaa gaaacaattt
    11341 tcccgcggcg tgaaaatcca tctgcggtaa taatcatttt tgaaccagct gcttgtacgc
    11401 gtgtcataac tgcatccgaa gcaaatcccg aaaatattgg tgaaataatt gctccgattt
    11461 tcattacagc tagcatcgca acaactgttt ccggaatcat cggcatataa attgttacac
    11521 gatcgccctt ctcaataccc gcttgtttca aaccattggc cacacggctt acccaattgt
    11581 caagctcttc atatgtaaat gattttgaag ttccattttc cccttcgtac tgaagtgctg
    11641 gctgttttct tgtcacttca tccgcaatcc agcgggataa agctgattct acaacgttac
    11701 atgttccatc attataccac tgtgcaaatg gcgtaccatt ttctaaatct aacacttctg
    11761 tataaggttt catccattga tagccaactg ctttttctgc ctctccccaa aaccaagctg
    11821 tttcctcaat agatttatta taaaaagttt catagtcttc atatcccaat gatttcatcc
    11881 aaccatataa acgtgttttt tccttatact cttctgttgg aaaccaaact gcttgtttca
    11941 atgttttccc ctccttgact ttttgagcaa gaaagcccta aatagggctt ttaaactgga
    12001 tatacaggat gtttacgatc cgtgaatact tgatatttac tcatatacat ttcgaaacgc
    12061 ccttttaact cttcacgtaa attgtttgga tgaacaatac catcaatcac catctctgat
    12121 gctaaatgat aaatatcaat atctttctta tactcttcac gtttttcagc tatgaagctt
    12181 gcacgctctt cttctggtaa agccgcaatt ttatttgcat atacagcatt gaccgctgct
    12241 tctggaccca ttacagcaat agaagctgtc ggtaatgcta agcagcaatc tggttcaaat
    12301 gccggacctg ccattgcata taaaccagct ccatatgctt ttcgaacaat gatagaaatt
    12361 ttcggtacag ttgcttcact cattgcagaa atcatttttg caccgtgacg aataatacca
    12421 gcgcgctcta cttttgtacc aatcataaat cctggtacat ctgcaaggaa taataatgga
    12481 atatggtatg catcgcataa attaataaac ttcgctgctt tatcagctga atcgtggaat
    12541 aaaacgccac ctttcatacg cggctgattt gcaataatac ctattggctt accatcaatg
    12601 cgtgctaaac ctgtaatgag ttcttgagca aataattttt tcacttcaaa gaatgagccg
    12661 tcatctataa ttctgttaat cagatctttc atattgaaag gagcattttg attttctgga
    12721 atgatttgtt ctaacgtttt atcgaactgt ttcggttctt gaggtgtcat caatggagtc
    12781 ttttctaagt agttgcttgg aaaatatgaa atgtattgtc tagcctgtgt aattgcatct
    12841 tcttctgtct tacataaaac gtctccgcat cctgatactg agcaatgcat acgagccccg
    12901 cccatttctt ctaaagttac cttctcaccg ataaccattt cagccatacg tggagatcct
    12961 aaatacatag atgcattacc ttccaccatc ataacaacgt cacaaaaagc tggaatatat
    13021 gcaccaccag cagcagaagg accaaataat aaacaaattt gtggaacttt acctgataat
    13081 ttcacttggt tataaaagat tcttcccgca ccgcggcgcc ctgggaacat ttctacttga
    13141 tctgtaatac gcgctccagc agagtcaact aaataaaata atggaacacg taacttttca
    13201 gccgtttctt gaatacgtaa aatcttttca actgtacgag ctccccatga tccggctttc
    13261 acagttgaat catttgccat tacgcacgca gtacgcccat gtattttacc agttgcagtt
    13321 acaacaccat cagccggtaa ccctgtttgc tcacaatttg caaataatgc atcttctaca
    13381 tattcgccat tatcaaatag aagagctaaa cgatctcgaa caaagagttt tccttttgct
    13441 ttgttttgtt catgatattt cggtgctcca ccttgtttaa tcgtttcaac tcgttcttca
    13501 aaattatttg attgttgttt ttgttctaac acatttactc ccccttatac atcggtttgc
    13561 gtttttcctt aaatgcctgt aatccttcta atctatcttc cgtatggatt acaccctcgt
    13621 acgcctgttt ttccatttgt aatccggtat gtaaatctac ttgaacacca ttagaaattg
    13681 cttcttttgc taatcgaact gcaataggac cattactagc aatttgattt gcaatttcaa
    13741 tcgctttctc ttctagtaaa tcagctggta cgacgaattc tactaaacca tattctttcg
    13801 cttcttgcgc cgaaatacgt cttcctgtat aaattaattc tttcgctcta ccaacaccaa
    13861 ttaatctcgg taaacgctgc gtaccacctg ctccaggtat aattgcaagg gtagtttcag
    13921 tcagaccaag gcttgcattt tcagaagcga ttctaaagtc acaggctaaa ctcaattccg
    13981 taccaccacc aagagcaatt ccattaatag ctgcaataac tggttgtggt aattgttcca
    14041 ccatttccat agtagtacga atcataccaa ccgcatggcc aacttgctct tcattcatac
    14101 cagctcgttc ttttaaatct gcgccagcac aaaacgcttt ttcaccagcc cctgttaaaa
    14161 taactacacg tgtatttgac tcttcactta tttccgttaa tattgtttgc aattcttcta
    14221 ataacgctaa agataaagaa tttgcttgtc tttcacgata taacgaaatc tttacaacat
    14281 gcggtgttac atagtcaact gaaatatttt gtaattgtag catcttctca cctacttatc
    14341 gttttatgtt gaagcgctct atacacatga ctcggtaatt ggatatttaa cttactttga
    14401 ataaattgac tagctctcca taacttttct tcgtctatat ttgtttggac acctaactta
    14461 tggagcatat gcactaaatc atcagttgca acatttcctg atgctcccgg tgcatatgga
    14521 catcccccga gtccaccaca agaactatca aacgttgtaa taccgtgttc taaagacttc
    14581 actacatttg caagtgccat cccatacgta ttatgaaaat gcattgcaaa ctgcgaagca
    14641 tcatatttct ttaatagatg ttctaatact tgttctactt gtaatggatt cgctacacca
    14701 atcgtgtcac cgagagaaac ttcataaatg ccgtatgaaa atagttgatt acatatttca
    14761 tcaactgctg cggcacttat atctccctca tacggacatc caaatacagt agaaacataa
    14821 cctctaacct ttttcccttc gaatattgcc tgttttgtta tatcttcaat aacagttaat
    14881 gcttctttaa ttgatttatt aatattactt ttattatgag attcactcgc tgataaaaaa
    14941 acattcacct catctacatt ttgcaaaaaa gctcgttcca aaccattttg atttggaaca
    15001 agcgcagcat atgtaacatt gggatccctt tttagctcag aaaagacatc atttgcatcc
    15061 gctaaggcag gaacccattt tgggtgaacg aatgaggaaa cttcaacgta cgacaatccg
    15121 gcttctgtaa gtagttgaat ccattttact ttatcttttg tgccaacaat ctttttttca
    15181 ttctgtaagc catcacgtgg ccctacttct ttaatgacag caaaattagg tagtttcaat
    15241 tcgcttcccc ctatatctcc ctattcaatt tctagtaata catctccttc atttacaaaa
    15301 tcgccttctt gcacattaat tttcataact gtgccagctt cttctgaaat gattggaatt
    15361 tccattttca tagattccaa aatgacgaca tcctgctctt cctctactgt atctcctact
    15421 cctacaacta tcttccaaac atttcctgcc atcgatgcat atactttcgt catcattttt
    15481 tcccccttaa tattcataaa tcttattttt taacaagctg tttcgttacg aaacccgttg
    15541 tataaatacc acttttgaac acatcgtctc cgagcacttg cagtagcatc ggtgtatttg
    15601 ttttaatacc ttcaattttc aactcctcta gagcattttc taattttgaa attgcctctt
    15661 cacgagtttc accatgagca atgacttttg caatcattgg atcataaaac ggtgtaattg
    15721 ttacatgatt ctctaaaaag tgatccatac gtatatttga tggtaatgtt aaatctgtaa
    15781 ttttcccagg tgacgggaag aatgttttcg ggtcttctgc ataaatacgt gcttcaatgg
    15841 catgaccact acgttttaca tcatcctgag taaatgatag tttctctcca cttgcgataa
    15901 gaagttgttg ttctacaaga tctaaccccg taatttcttc tgtaacggga tgctctactt
    15961 gtaatctcgt attcatttct aagaaataga aatttttctg atcatctaca agaaactcaa
    16021 ctgtacctgc atttgtatac ccaagagctt tagcagcttg tacagccact tctcccattg
    16081 cttttcgtgt accttcatct aaaaaaggtg aaggtgcttc ttcgattact ttttgatttc
    16141 ggcgctgtac ggaacattca cgttcccata agtacactgt gttaccatgt gtatctgcta
    16201 aaagctgaat ttcaatatga tgcgcgtctg caatataacg ctctaaatac atttctccat
    16261 taccgaagaa attttgtgcc cttgttttgt tactttcaaa tgctttggtg agcgtttgct
    16321 cagtttccat caactgcatt ccaatgcctc cgccgcccgc ggatgcctta agcattaatg
    16381 gataaccaat ttgttttgca atttcaattg cctcttcagc agtttcaata tttgtagtaa
    16441 tacctggaac tactggtaca tctgctgctt gcattgctat acgtgactca attttacttc
    16501 ccatcttcgt aatgatttct tctgaaggac caataaatac gattccttct tctttacagc
    16561 gaatcggaaa agatggattc tctgataata atccgtaccc cggatggatt gcttcaacat
    16621 ttgtcttctt agctatttca ataatttttt caaggtttaa atagctttct tgaactcgtg
    16681 gaccacctac tagataagct tcatttgcca tttttacatg aagggcattt tcatcagcct
    16741 cagaataaat agcgacggta cgaattccaa gtttttgaca agttttcata atgcgaactg
    16801 cgatttcccc gcgattggca attaatattt tttgaaacat agtgattcct cctttttatc
    16861 tacatcctaa atgtctagca attacgagac gttgaatttc agaagttcct tcaccaattt
    16921 ctaacagttt tgcatcacga atatgtcttt caacttcata ttcacgcata tagccataac
    16981 cgccatgaat ttgtactgca tgattcgcaa tacgactagc tgcttcagat gcaaatagtt
    17041 ttgccatagc cgcttcttta ccgaaaggtt tatcgttatc ttttaaccaa gctgctttat
    17101 gtactaaatt acgtgctaac tctacttcag tcgccatatc cgctaattta aattgaatcg
    17161 cttggaaatt agaaattgtt tttccaaatt gttgacgttc tttcgcatat tgcaatgcac
    17221 gttcaaatgc agattgtgca atacctactg ctaatgctgc aattgaaata cgtcctccat
    17281 caagtgtata taagaattgt ttaaatcctt tattaacatc accaagaata ttttctttcg
    17341 gtacacgcac accatcaagt acgatttcac aagtattaga agcgcgaaca cccatcttat
    17401 cgtaaggact tgagatcgtt aatccttcac ttgtagtcgg tacgataaat gcagaaatac
    17461 gttttctacc attctcttca acaccgttga tagcggttac aataattgta tttgcatact
    17521 ctgcgtttgt aatccagcac ttttcaccac tgattacata ctcatcacca tctaataccg
    17581 ctttcgtttg tgtgcctcct gcatctgatc cagcgtttgg ctccgttaat ccgaaagcgc
    17641 ctaacgtttt acctgatgcc attggaacta aatatttttg tttttgttct tctgtaccga
    17701 aataataaat tggagaagca cctaatgaaa ttgttgcagc gtagcttaat cctgtaccac
    17761 cacaagcacg accaatttct tcaactgcta gcgcgtacga tactgtatcg ccacctgaac
    17821 ctccatactc ttctgggaat gggatgccta ataatcctag ttcgcccatt ttttgaaatg
    17881 tttcatatgg aaactctgca gttttgtcat aatacacagc tttcggtgcg atttcctttt
    17941 cagcaaagtc acgtaccatt tctttaatca tttgtttttc gcgagttaga gtaaattcca
    18001 ttccgctaca caccccttat cgaatattga gtttcgacag cgtgcgagtt tctactacaa
    18061 acattacttc ttaaaagaca agaatattag ttagacaatt gctacaattc tgtcataact
    18121 taattttaaa acagattctg tgctaatgca caaaaaaatt cctacattgt tctacaacaa
    18181 cataggaagt tttatgtcga attatgtaat ttattgttta ataatctcta ccttttcccg
    18241 aatcagaaat ttctactaac gcttcaggat atggctcaaa atatgtttgt cctaataaat
    18301 acttttcatc aaaccgaatg gcccatgatt ttaaaattgc aagcaaacta ctaagtggta
    18361 ttttcttttc tgcatacttt tgtatcagtt ctaaaaaata atctttttct tgttttttta
    18421 atttcgtttt aaaatatccg aaaatatgtt cacatacatt tacattcgat gtatagcggg
    18481 gcgcgcgcaa aaataattca tataaagtct tctcataatt atcaaataca atttcaatcg
    18541 tttcattttt ttgatttgca ataatacgcc ctaattcttt ttgttttacc tgattatatg
    18601 ccataaataa atatttattg tccgactgaa acgatacaag gtctttcata tttttattat
    18661 gtttaatcat tttgtaatat gcgattgtaa ataaccttgt aaagaaatgt tctctaataa
    18721 taaaattcga caatctacct tcttcttcaa ttggaaggtg cgaaaaattt tttaatactg
    18781 ctccgccaaa taagcctggt ccctttcctt ttgctggcgc tttttcaaaa ccagaataaa
    18841 ttttcacatc acgcgtacca caacttggcg agcgattctt taaaataaat ccatccacat
    18901 cggatatcgt ttgtaaaaat ccatttgaaa attgctccat tttttcagta acgtcttctc
    18961 ttgtcgacgg ttgcacaagt gtattcacac cattttcttc tacgattcgt atcgtttcac
    19021 gaggaattcc caatccaatc tcgacttctg gacaaacagg tataaatgta acaaatggct
    19081 gcaaatttcg tattgttaca tccggaatca tttctccatt ataacgacaa gcatcaaatt
    19141 ctaaacattt acttacgacg attgtaggtt ttgcaaattg tcgcatttca ttacctccgt
    19201 ggcgttagtc cgtacaaaat aaattgaatc gtattttcaa tttccaattc atcatcccaa
    19261 ttctcttcag gtaataataa aaaccgagtt aatagaaatc ctaaaacagc tgataatgta
    19321 agccgtaaca cggaaggtgg tggcatctca ataattcccc cttcttcttg aaactttaca
    19381 attaactttt taaaatgtga aagcagttct gtttctacta attgttgtat ttcacttttt
    19441 agctctggct gaaacggcac ttcttgaatt aatattttaa tcattggaaa gtgctttttg
    19501 gcaaattcaa atcgattatg aatgactacc cttaaaagcc cttcatacga ttcataatca
    19561 gttttaaata tctctttcgc aaaagcttgt acgaaaaatg gtgcagcaaa ctttgttaaa
    19621 gttggcatta cgaccgctaa caataaatct tttttcgtct tatagtagcg gaaaatcgtt
    19681 ccttccgcta caccagcacg ctttgcaatt tcacttgttg aagttgaagc atatcctttt
    19741 tctccaaaca tatcaacagc tgcttctaaa atacgcattt gacgttcatt tcgattatca
    19801 gtattagttg cagcaatcaa ttcctcaagc caatccttct tcatgtacaa agctcctttt
    19861 tgtcattatt atattttgcg atgtttcttt aaagcaaata cattccctac tgcaaataat
    19921 agtgaaaaaa gtagtaatac agtaagatcc aatgcaattt ctgtaaatcc ttgatttcga
    19981 atcatcactt gcctcattgc atcagcgccg tatgtgagtg gaaataattt ccctaacatt
    20041 tgtagccact tattcataga ttcaattgga aacaagccag aaaagaagat ttgtggcaca
    20101 ataactagcg gtataaactg gatcatttga aattcattat ttgcgtatgc tgataaaaac
    20161 gtccctaatg ttagtgccgt taaagagagc atacatgtaa taagtagcgt tagccatata
    20221 gaacctgcta catataaatc taaaacatag actgaaaaac ttacaattat aacagattgt
    20281 atgaatgcaa aaattccaaa accaattata tatccaacaa ctatttccca tcgtctaact
    20341 ggtgtggaca ataatcgctc taatgtacca cttaaacgtt ctcttacgaa agaaactcct
    20401 gacaaaatga atacaaagaa aaatgtaaag aatccaatta acacgggacc gagcccatca
    20461 aacatcgtaa agtctttaga gccatgtaaa taattcactt caggtttcat aatcgataca
    20521 tcattcttct ctgtgctctt ttgcaatact tggagtacag cacggttttt cgacgaatca
    20581 ctgccttcta acaaaagatt tatttttcca ttctctaaat gaattactgc atcgatcttt
    20641 tgtttttcca actcagaaat cgctttcttt ttgctatatt cataaattga ggcttcttga
    20701 tttttcatca cttttactat agaagcgggc acatcaacta cagcaatatg tggtttataa
    20761 tctttttgtg taaatactaa agacaatagc caaagtaata acattggtgc cccaaacatc
    20821 atggctaacg aacgtttatc tcgaaaaaat tgacgaataa tacgaatgat tacaccatta
    20881 actctcacga ttcaaccccc tcttctaaca aaaagacatc ttcaattcgt ccagatgata
    20941 cacgtttttt caattcctct ggcgttccaa ccgcaactaa gttcccttct ctaatcaacc
    21001 ctagacgctc acaaaactct gcttcatcca taatgtgcgt cgttacaata atagttgtgc
    21061 ctttcttttt aagttcataa aattttcccc agattgtttt tctaagaagc ggatctatcc
    21121 ccactgttgg ctcatctaaa attaatattt caggttcatg aagaagtgct attgctaatg
    21181 atagacgctt tttcatccca cctgaaaaat gctgtacttg ctttttcata tgttgtgata
    21241 attgtaccag gtcaaaaacc tctttgattc tttccttttt atgctttccc tttaatccat
    21301 acatcgttgc aataaaatct gcattttcat atgctgatag ttcttcgtat aatgcatcag
    21361 cttgagccat atagccaatt cttttcatct catttaaatt tggcatgtta atgttgtata
    21421 caaatacatc acctttagat gcctgattaa tacctgcaat caatttaata agcgtcgttt
    21481 tccctgatcc tgaaggccca actaaaccaa atatctctgc tttttcaatt tgtaatgaaa
    21541 gatcgtgtaa aacttctttt ttcccaaaac ttttcgatac attctgtaaa acaattgaag
    21601 gtttttgcat gtattatccc tcttttctat aaaatgagtg agtactcact tttattttac
    21661 tcttgcgtaa ttatatgtca aacttcattg attagtattt attttcaatc aacaatatta
    21721 aacaatgaaa cagaatcgac attagaatat aatttcttaa agtcgactct gtttcattta
    21781 aactatgcat tttactttat gtttctaaat tcatatactt cctaattcta gcaaggtcta
    21841 aagaatattc gataactaat tgctgtaacg gtaaaataac tgtatcggga tataaatgtg
    21901 catattgtaa tgtttctgca tatttttcta atcttttttc taaatatttt ataatttgct
    21961 caggatggct cactaataaa cattgacaat aataatgtat ttgttcctca atcgccgtat
    22021 actcttcaat ttcatattct ttatgcatgt gtacacccct ttaagttttt tacataaatt
    22081 ccttatcaca cttttcactc gactaatttt taagtttttt tgattattta cactataaca
    22141 aactcttcag gtcaaatttt gttactttat gtaacgtaga aaatttttaa caaaattgta
    22201 atgttaactc gtacaaaata cataaagccc ttttactcat tctgtacata aaaagtcgcc
    22261 caatttaatt taactgggcg actacaattt ctggcctatt caaaattctt tgcggaatga
    22321 tactattgcc taatcctcta ctaaccacca ttgatgtatt ttgttcttca tataaacctg
    22381 ctgtatattt aggtaaaaca ccttgatttg gagcaactaa tccgctgata aatggtaacc
    22441 taacttgccc accatgagca tgccctgaga aaactaaatc tattcgctcc tctgcatact
    22501 cctcaataaa ttctggccta tgggataata atacattata tctatttggt tgcgtttcaa
    22561 ttttcgcttt tacaattgca tcttttacaa tacttccttc attaatatct ctgttattaa
    22621 attccggatc atcaatacct aacaagttta tttcttgtcc gcctttttgt attattacat
    22681 gttcatttct caaaacagta acatggtttt tctttaattc tttttctaaa ctgttatatt
    22741 ttcctgacca tttttcatgg tttcctgtta caaaatatac cggatactcc tttacaagtt
    22801 ctcgtattac ttgcatacta atttcttcat cgtacgattt actgtctatt aaatcaccag
    22861 taatagcaat aatatctgga tttatgcttt ttactttttg aattaaaatg tcttgattat
    22921 caccaaattt tttattatgt aaatctgaaa tttgtagaat tttataccct ttaaaagcgg
    22981 agggaatttt actagaggtt attttaacct cagttatact tattaaattg ttctgtaaat
    23041 ataaaaagat acaaatacct actattgtac cgataagtaa tatgattctt ttagtcttct
    23101 tgttcatttt tcctcctaaa atcttaatca gaactacaat tctaataaac attccgtgcc
    23161 ctttgaattc aaaaaactga aactttccaa ttaatttgaa gtatttttca tagtgttata
    23221 cgtctctaat aaacacttac tgctgtttcc aatctccttc gtattaactt actataaagt
    23281 ggagctttaa tatcctaggc gtcctgcatg agtgtatgat atcatgctca ttctctagtg
    23341 aatttatagc gaatccctgg aagctcttca tcatattatc atttatctta tttagttaat
    23401 aacgatataa tgataattcc taaagttttt tataaaaaaa ttgtgtattt ttctcgaagt
    23461 atatatgaca tttgcttgca aatatattat taccactacg attttaattt gtttaaagcg
    23521 tatatagaga gaattaaaac attaaattcc cttatgaaaa gttattatta tattatttat
    23581 tagaaaattg aaaaaatgtg tgtagataga tatcattgta aatgaatata taattaactt
    23641 taattttctg acatagtttc acataattct taaactattt tttgcgtgca ttatgaaata
    23701 atatattgca ccgtgtcagt ctttaaaaga ttatatatca taactttaag agaggaagga
    23761 aaactatgaa gatgaaaaga aaaatcatga tgacaacagc acttgcggct acattagcta
    23821 caggtgcact accaactaca tcggtgtttg ctgctgaaaa agaggctcct atccaacaaa
    23881 aagaggcaca agtgagtatt caaccatttg cacaaaataa tttggaaaca gccgttaatg
    23941 ctgccttaaa tggcccagaa gtcaaaaaaa taaaagtatt tgagcatgaa tttaatgtaa
    24001 aagaaataga agtagtaaat ctaggtgctg gaaaaaaata tgttaaggga caaatttctc
    24061 atcatttaag ttttcgtcca gatgatcaat tttattatga gtttacagtg caagatggaa
    24121 aggtaataga taagcctgta tttaatattg atagaggtgg ttggacacca tttgctgctc
    24181 cacttttatc aattcttgct gcctataatg ggattccagt taacccaaat gatttaaatg
    24241 cacttggtca gcagcttgga aaagttatag atggaagctg ggaacatgca gcccaatcta
    24301 tcgcaactgt agttagttta agtttcaatg agtagaactt tttaattttt attagccttg
    24361 cagaggccca tttttcgtag gtaaccttgt tataagagat tctgaaacag ctataaatag
    24421 atttttacca ctcagtcaca ttatcttgat ttgttaacca ccttatcatt cattatatgt
    24481 cacagaatag aagtcttttt taaggcttct gttttgtttg tatacaatac gataaaaggt
    24541 tgttttttcg agtctatact tcgattcttt aagaatccgt ttggttatta agtacaattc
    24601 ataacaacaa attattaaag tctcaaataa gttactcccc ctatttttaa ttattttcaa
    24661 acacaaaatt tcattacttc aaaatgaaaa caataaatat agtacaaaat catcttaatc
    24721 tattgtttaa aggtcaggag agataaaatg aacaaaataa aaataataaa tttctttaaa
    24781 attagcatcc tcacatgttt tacactagca agtttaagta caccatctcc tattttagct
    24841 gatagtcatc caggttattc ctatgaatcc aatataggat atcaaaatcc atcgtggatg
    24901 tcgaaagtag aagattcaac aaaactaagt aaaatatcta ttccagggac tcacggtaca
    24961 atggctttac atggagcaag ttttcttgat gaaaatttga caagaaatca aactatgagt
    25021 ctacctcaac aattaaattc tggaattcga tatgtagata tgcgtgttaa acgtgtaaaa
    25081 gattcttttg caatgtacca tgggattgta aatcaaaaag caatgtttga agatgtatta
    25141 aaagaggcaa ttcaattttt aaaagattat ccgacagaaa caattttaat gcgcttaaaa
    25201 gaagaaacta ctcctgaaag tggatcacta tcatttgag
//
