LOCUS       NZ_CP022098            20987 bp    DNA     circular CON 17-FEB-2024
DEFINITION  Cystobacter fuscus strain DSM 52655 chromosome, complete genome.
ACCESSION   NZ_CP022098
VERSION     NZ_CP022098.1
KEYWORDS    RefSeq.
SOURCE      Cystobacter fuscus
  ORGANISM  Cystobacter fuscus
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Cystobacter.
REFERENCE   1  (bases 1 to 12349744)
  AUTHORS   Rupp,O., Goesmann,A. and Sogaard-Andersen,L.
  TITLE     Sequencing and comparative analysis of myxobacterial genomes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12349744)
  AUTHORS   Bruckskotten,M., Treuner-Lange,A., Rupp,O., Goesmann,A. and
            Sogaard-Andersen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2017) Department of Ecophysiology, Max Planck
            Institute for Terrestrial Microbiology, Karl von Frisch Str. 10,
            Marburg, Hessen 35043, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 09-AUG-2016
            Assembly Method                   :: Celera Assembler v. 8.1
            Expected Final Version            :: yes
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/17/2024 10:04:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,093
            CDSs (total)                      :: 10,016
            Genes (coding)                    :: 9,906
            CDSs (with protein)               :: 9,906
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 26 of 110
            Pseudo Genes (incomplete)         :: 101 of 110
            Pseudo Genes (internal stop)      :: 1 of 110
            Pseudo Genes (multiple problems)  :: 17 of 110
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:24:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9288623
            Orig. end                         :: 9309610
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20987
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="48"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20987
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20987
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10987](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10987
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(444..2309)
                     /locus_tag="CYFUS_RS37615"
                     /old_locus_tag="CYFUS_007435"
     CDS             complement(444..2309)
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002625482.1"
                     /locus_tag="CYFUS_RS37615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007435"
                     /product="amidohydrolase"
                     /protein_id="WP_095989585.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 3.6e-08, bitscore:
                     32.2, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADMIVKNARITTLDRDNPSATALAVADGNLLAIGEEAAVMAHAT
                     ARTRIIDAGGRRLIPGLNDSHLHLIRGGLNYNMELRWDGVRTLADAMAMLKEQVARTPA
                     PQWVRVVGGFSEHQFAEKRLPTLRELNEAAPETPVFILHLYDRALLNRAALRAVGYTKD
                     SPEPLGGRLERDHAGNPTGLLLAKPNALILYATLAMGPKLPPEFQLNSTRHFMRELNRL
                     GITSVIDAGGGFQNYPEDYEIIQKLHADGELTVRIAYNLFTQKKGGELADFDKWSRMLT
                     PLQGDGMLRHNGAGEMLVFSAADFEDFREPRPELPQGMEGELEDVVRLLAQRRWPFRIH
                     ATYDESISRVLDVYEKVNREVPFDGLHWFIDHAETISDRNIERVRALRGGIAIQHRMAY
                     QGEYFAERYGSAATRNTPPVRKMLEAGVPVGAGTDATRVASYNPWVALYWMVTGRTVGG
                     LSMYGDDNLLEREEALRLYTHGSAWLSHEQDRKGILKVGQYADFALLSSDFLHVPEEAI
                     KDITSVLTVVGGKVVHGGGDFGPLAPSLPKPMPDWSPVNRFGGYQGGTQAQARAMFARA
                     QRHSHSHGTSCAVHGHGKDHAAHHPTPGGGLRDFWGALGCLCYAF"
     misc_feature    2294..2308
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    2346..2360
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.45"
                     /tool="antismash"
     misc_feature    2347..2360
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.16"
                     /tool="antismash"
     gene            complement(2393..3052)
                     /locus_tag="CYFUS_RS37620"
                     /old_locus_tag="CYFUS_007436"
     CDS             complement(2393..3052)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002625481.1"
                     /locus_tag="CYFUS_RS37620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007436"
                     /product="hydrolase"
                     /protein_id="WP_095989586.1"
                     /transl_table=11
                     /translation="MPPKASPTPGKGLLSPTDHALILIDHQSQMTFATHSIDIAQLRNN
                     TALISKAAAGFRVPTLLTTVAEKSFSGPLFPEITEAFPGAKVYDRTSMNAWEDKQVITQ
                     INAFEKERLVFAGLWTGVCIVGPVVSAIDQGFKTFVITDACGDVSDEAHERAVQRMIQA
                     GAVPMTSLQYLLELQRDWAREATYGLTTGIAKTHGGGYGIGLQYAKTMFGASEGGH"
     misc_feature    complement(3108..3123)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.78"
                     /tool="antismash"
     gene            complement(3175..3546)
                     /locus_tag="CYFUS_RS37625"
                     /old_locus_tag="CYFUS_007437"
     CDS             complement(3175..3546)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS37625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_007437"
                     /product="hypothetical protein"
                     /protein_id="WP_095989587.1"
                     /transl_table=11
                     /translation="MQRLFSMFPEGGPGVGLLLLRLSVALSLLPHLSGGPLMNAMLALL
                     AIGLCLGVLTPTLAVVCFLFSFYDFMVMGGVTLPEAGIELLAAGALALLGPGAHSVDAW
                     LFGRRVVTLPPRKKTRVDE"
     gene            3780..4412
                     /locus_tag="CYFUS_RS37630"
                     /old_locus_tag="CYFUS_007438"
     CDS             3780..4412
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002625478.1"
                     /locus_tag="CYFUS_RS37630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007438"
                     /product="response regulator transcription factor"
                     /protein_id="WP_095989588.1"
                     /transl_table=11
                     /translation="MSSTNPPIRILIVDDHPLLREGLSSMIAGQPDMKLVAEAENGEQA
                     LQAFRDHLPDITLMDVQMPTMNGIDAITAIRTEFPTARIIILTTYKGDMQALRAIKAGA
                     SGYLLKSMLRKELVETIRSVHAGRRRIAADIATEMAEHVADDELTARECDVLRLVASGS
                     ANKEVAARMGISEETVKTHMKNVLTKLGAKDRTHAVVVALKRGIIDI"
     gene            4462..7536
                     /locus_tag="CYFUS_RS37635"
                     /old_locus_tag="CYFUS_007439"
     CDS             4462..7536
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="CYFUS_RS37635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007439"
                     /product="sensor histidine kinase"
                     /protein_id="WP_095989589.1"
                     /transl_table=11
                     /translation="MVGTRLRGPVRFWQQALFLGLVAVLTFFADTARAFSQDRRLTQFH
                     HTRWTIKEGAPGQISAIAQTEDGYLWLAAAASLYRFEGIRFERFEPPSGDPFSTIQTLY
                     APPDGGLWIGFQLGGVAFLKEGHLTRYHGTEGAPTRSVSAFATDRDGNVWASEMRGGLF
                     RLSGTRWEQIGESWGYPGSKSRHLFVDRDGTLWVATEKTLLYLPRGAHRFVPTDVSVGW
                     VFQLRQAPDGRIWMTESGGDVRPIPVPGHGQTENPPTLHVESAGMLFARDGSLWLTTLG
                     DGVRRLAHPERSSAGDAAEVGGEVESFTEKDGLSADYAWPVLEDREGNVWVGTSGGLDR
                     FRTSSMVLAEFPRGSHDFALIAGNAGEVWAGTTNRPLMRLHDGEVSFEQLGSPVRSAYR
                     DEEGVVWLGADDGLWRVEDGRLSRVTPLPDPLAQVQAMTRDRHGTLWVSLTTGGLMQWE
                     DGRWHSVEEPLGPLDGESIHTAMTDGRGRVWLGHQRGIITRVDGDEVRRFTEDDGLRLG
                     VVAALTAGRRYVWVGGQFGLAFHDGERFRPLVADGDESFRSVSGIIERPDGSLWVHAVP
                     GVFHVPAEEVRRAVGDPGHRVRYELFDFLDGLPARPTLLRPLPTAIAGGDGRLWFATSN
                     GVVWIDPERIARNPLPPPVSILSVKADGRRYAPAADVTLPIHPANLEIDYAALSLSIPE
                     RVRFRYRLEGVDEHWQDVGTRRTAYYGNLAPGQYRFHVIASNNDGVWNEHGASLEFVVP
                     PAVHQTWWFRTLCMAAGLLLLWLMYLLRLRQLTAKMRGRLEERHAERERIARELHDTLL
                     QSVQGLVLRLQAVAEQLPEHEPARQAMEKALDRADEVLAEGRDRVMDLRSSAHAGRDLS
                     DALVRVGKELAENLPMSFRLVTEGVPQELNAAVQVEIFLIGREALLNAFQHAGGTAVEA
                     ELHYDSDELRVRIRDDGAGVDPEVLEMGGRPGHWGLAGMHERAARIGATLQVWSRTDAG
                     TEVELKVPAEIVYRRRPKAAWWSRLKDIARLARGR"
     gene            complement(7560..8435)
                     /locus_tag="CYFUS_RS37640"
                     /old_locus_tag="CYFUS_007440"
     CDS             complement(7560..8435)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (24-266). E-value:
                     6.8e-27. Score: 86.6. Matches aSDomain:
                     nrpspksdomains_CYFUS_RS37640_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="CYFUS_RS37640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007440"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_095989590.1"
                     /sec_met_domain="PF00561 (E-value: 4.7e-20, bitscore: 71.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.9e-20, bitscore:
                     73.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTFTTADGCELDYHLAGSSSSERTLVLLHGWSQSRAMFDRVIPM
                     LASHYRVVSYDQRGHGESGHPPHGARIARLARDLDELLTYLGIERADFAGHSMGASVLW
                     SYLDLFGSAKVSSLIIIDQPSACTVLPWLNKVEATEVGAILDFPGAEAFCKGVLGPDAA
                     AVRHDFLVSMLTKQISSADLAWLYQENLKLEGGFGSRLLLDHIMQDWRDVLPRIDVPTL
                     VMAGEVSHVNPASQKWSAEQIPGAQLRIFTAEEGGSHFPFFERPEPFATALRSFLDAQP
                     VPRARAGAVA"
     aSDomain        complement(7638..8363)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CYFUS_RS37640_Abhydrolase_1.1"
                     /evalue="6.80E-27"
                     /label="CYFUS_RS37640_Abhydrolase_1.1"
                     /locus_tag="CYFUS_RS37640"
                     /protein_end="266"
                     /protein_start="24"
                     /score="86.6"
                     /tool="antismash"
                     /translation="TLVLLHGWSQSRAMFDRVIPMLASHYRVVSYDQRGHGESGHPPHG
                     ARIARLARDLDELLTYLGIERADFAGHSMGASVLWSYLDLFGSAKVSSLIIIDQPSACT
                     VLPWLNKVEATEVGAILDFPGAEAFCKGVLGPDAAAVRHDFLVSMLTKQISSADLAWLY
                     QENLKLEGGFGSRLLLDHIMQDWRDVLPRIDVPTLVMAGEVSHVNPASQKWSAEQIPGA
                     QLRIFTAEEGGSHFPFFERP"
     misc_feature    8526..8539
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.82"
                     /tool="antismash"
     gene            8650..9984
                     /locus_tag="CYFUS_RS37645"
                     /old_locus_tag="CYFUS_007441"
     CDS             8650..9984
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="CYFUS_RS37645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007441"
                     /product="cytochrome P450"
                     /protein_id="WP_157758880.1"
                     /sec_met_domain="p450 (E-value: 4.2e-77, bitscore: 259.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVPTAPARWPLLGHSWPLLSRPRDFLLSLEKVGSLVRVYIGQMP
                     MVVITDPELTRQVLHDSATFDKGGSLYEKLSELTGNGLLTSQSEPHKRQRRLVQPAFKK
                     SSIKDYSSVMAGVVEVALRDWEDDAVVDMKAAAYHIVSRIAARSMFSAEMADASIARIA
                     EALSIYLNGLFVRTVGPGVLFERLPTPGNLRYKQALEVLHQEISRIISEYIASGVERED
                     VLSILLREKDEGDGAGLSPQEVHDQVTTLLLAGIETSAATLCWCLYLLSHHPDVTQRLQ
                     AELDGVLGGRAAQWDDIPELKQTRRIVMEALRLYPPGWLFTRVTMRDTVLGAYPLPRGT
                     GIAYSPYLLHRSPSSFEQPDRFDPDRWLPERSNRLSMNSFVPFGGGVRRCIGEMLGVTE
                     VMLTLATIASHWEARCVREGPIEPAPAHVSLIPKQLRMRVTRRKR"
     gene            10001..10987
                     /locus_tag="CYFUS_RS37650"
                     /old_locus_tag="CYFUS_007442"
     CDS             10001..10987
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="CYFUS_RS37650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007442"
                     /product="hypothetical protein"
                     /protein_id="WP_095989592.1"
                     /sec_met_domain="T1TS (E-value: 4.2e-70, bitscore: 236.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQQSIHQTLETVDWGPPPPLNKHYPGIHREADLWLESVGLTDKP
                     GRLAKHRRIEVPLFAAMAYPTASRDNLLLAHDWMAWLFEYDDQFDEGDDGHSTDRARQS
                     RESLLSILDDTSTVAREVPRRTLQSGLSDIWSRLRAVAPPGLRERFAGHVADYLESYEW
                     ETHNRRVGYCPDVEEYLAKRQHTGAAHPCFDLVVPAAGIQYGRVDWTNARRGRLEYLSS
                     EIITLSNDLVSFPKEMEQGDVHNIVIILMRRHGHPEQEAVLRTVGLLESRIADFEREAS
                     GLARAPLGLNDDTKLYIHGLKVWYQANYFWSLKCRRFIVDQVDEAAH"
     misc_feature    11049..11065
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.68"
                     /tool="antismash"
     misc_feature    11053..11067
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.68"
                     /tool="antismash"
     gene            11420..13726
                     /locus_tag="CYFUS_RS37655"
                     /old_locus_tag="CYFUS_007443"
     CDS             11420..13726
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015352106.1"
                     /locus_tag="CYFUS_RS37655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007443"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_095989593.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 4.5e-08, bitscore:
                     31.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKSSTWPVGGVRPLRAMVVGCALVAPLSAIAGPSDTKQPPASAR
                     GVSLPPAVLVSDSREVSAGGARGYSLVTPAGLVIHRTERPVLALRSIQVPGTAIQLHTW
                     QESQTNGMRQSYTAYTRGGTEAVGRVRDTSYLVRLDAAQFDPLQVTQPLATRLLAADPD
                     NTLHLVQFLGAPLPEFREAIERQGGKVLRFLTDHTFVVDMDADAQKRVAELPYVRWVGP
                     YHPEYRLERELRESLMGLAPALAPQRYSIMLGESGAGRQEEVAALVRKLGGTVELIEQG
                     GLRVEATLTAAQLRQVARSNAVQFIDRWGGPGGVDMDIVRDVGGANYLEGLEGWTGQGV
                     RGEIFDTELLTTHQEWSTAPIIHSTGTTGSLHGSSCYSNNFARGANPAARGMIPSGQGI
                     FFRYSESTQFGGTKSRYDINKELINPAGPYRAVFQTSSVGSAQGTAYTTISAEVDDYLF
                     KHPILSTQSQSNTGSRNSRPQAWAKNIVSVGAVQHQNTASRADDRWNYTGSIGPAADGR
                     IKPDLSYFYDSIQSATGSGNANYTQFGGTSSATPQTAGHFGLLFQMWHEGVWSGFGGKA
                     DVFDSRPQMATAKALMINNAYRYNWQAGGSNADVDRYKQGWGTADIRRLYDRAPKTSVI
                     DETDLLTPLGVKTYDVTVPSGETELNVTLVFTDPMGTVGAAQTRINDLSLRVTDPNGTV
                     YWGNYGLTTGRFSTPGGTSNTIDTVENVFIQNPVAGKWTVEVLGDEIVQDSHVETTALD
                     ADYGLVVSGGVISGG"
     gene            complement(13869..15797)
                     /locus_tag="CYFUS_RS37660"
                     /old_locus_tag="CYFUS_007444"
     CDS             complement(13869..15797)
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002615615.1"
                     /locus_tag="CYFUS_RS37660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007444"
                     /product="YgiQ family radical SAM protein"
                     /protein_id="WP_095989594.1"
                     /sec_met_domain="PF04055 (E-value: 2.1e-20, bitscore: 73.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATPLRYAHPFLPVTRADMKARGWEQLDIIIVTGDAYVDHPAFGP
                     VLIARFLEGRGFKVGIISQPDWHSAEPFKELGKPRLFFGVAAGNLDSMLNRLTAQKKNR
                     SEDQYSPGGRTNARPDRATIVYAQRCREAYPDVPIVLGGIEASLRRIAHYDYWSDKVRR
                     AILFDAKADLLVFGMGERPIWEIADRLDRGELIEDLRDVRGTAYLINDEAMKVHEADPA
                     RRAADQKTVVLPSYEEVVADKEAFARMSRDFQMETNPGNGRPLAQRHGNRAVYFNPPAL
                     PLEDGAGKGDSASVAMDELYDLKFNRVPHPMYREQIPAYETVKHSVVLMRGCFGGCTFC
                     SITEHEGRVIQSRSAESVLREVRALRRMGDFRGTLTDLGGPTANMYKLKCKSEDIEKRC
                     RKLSCVHPGVCENLDTDHGPLIDLMKQVRQEEGIKHVFIASGVRYDLAERSPEYVKELA
                     AHHVGGQLSVAPEHVSKRVLEKMKKPGIESFERFQTMFACASEEAGKEQYDIPYFISGH
                     PGSELKDMVELALWLKQNGKRPRQVQDFIPTPMSVATAMYYSGLDPLKMEPVYTARGLR
                     EKKLQKALLLYWNPEQWPLAREALIQAGREDLIGRGPHALVPPETGAEASRRKQAEARE
                     RQERRAR"
     gene            15998..16642
                     /locus_tag="CYFUS_RS37665"
                     /old_locus_tag="CYFUS_007446"
     CDS             15998..16642
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011556061.1"
                     /locus_tag="CYFUS_RS37665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007446"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_095989595.1"
                     /sec_met_domain="HAD_2 (E-value: 4.1e-40, bitscore: 136.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPPKTIVFDLDGTLVDSLPDIITSFQYALESQKLPVPSVAEVR
                     ALIGLPLEDMYAHFAAPDQIPTLCALYREHYPRNFVTRSRPFPGAVELLRTLRERGYTL
                     AIATTKRTDMARRFVEALGLTSAVDHIQGTDGFPHKPAPDVIQRALAALGSEGLWMVGD
                     TTHDILAGRAAGLRTYAVTWGNHGADELATAKPDEIQADLSRLLEHLPARA"
     gene            complement(16658..17104)
                     /locus_tag="CYFUS_RS37670"
                     /old_locus_tag="CYFUS_007447"
     CDS             complement(16658..17104)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002625472.1"
                     /locus_tag="CYFUS_RS37670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007447"
                     /product="hypothetical protein"
                     /protein_id="WP_095989596.1"
                     /transl_table=11
                     /translation="MTDTRGERAGAGGQEALRENGMMRHLLDSLEAGKDIGHFGRLVFA
                     MVARYFLDEAELKWLLLQDPACDEAQALSLIEQVKAHDYSPPRREKVLQFQQQQDFPII
                     PNPEDPDEGNVYKDLRFPEHVYAHISEYREQKAHVHEAEAAHSA"
     misc_feature    complement(17139..17154)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.47"
                     /tool="antismash"
     misc_feature    complement(17149..17160)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.89"
                     /tool="antismash"
     gene            complement(17241..18083)
                     /locus_tag="CYFUS_RS37675"
                     /old_locus_tag="CYFUS_007448"
     CDS             complement(17241..18083)
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016041.4"
                     /locus_tag="CYFUS_RS37675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007448"
                     /product="sterol desaturase family protein"
                     /protein_id="WP_095989597.1"
                     /transl_table=11
                     /translation="MPMLPPRSPIDVALGVFFLNLLRYVVFALPAFVFFHRRTPRRFSS
                     RRLGPGPVSEKQARREILYSMGSLVIFGLVGVWMYALAEAGLSRFYTDDRHGPVWFVLS
                     IPVMLLVHDTYFYWTHRFMHWKPIFEHVHKVHHLSHDPSPLAAYAFHPLEAVIEAGIGP
                     LILLTLPVHRSAFLIFLTLQLFINVIGHLGVELYPRGFLRSPVGRWFTTTTHHHQHHQR
                     MKWNFGLYFNVWDRLLGTNHPQYESTFEALTTPVPESPAEEAAESEPALTGEFSSRPS"
     gene            18194..18988
                     /locus_tag="CYFUS_RS37680"
                     /old_locus_tag="CYFUS_007449"
     CDS             18194..18988
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (10-114). E-value: 3.2e-08.
                     Score: 25.6. Matches aSDomain:
                     nrpspksdomains_CYFUS_RS37680_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002625470.1"
                     /locus_tag="CYFUS_RS37680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007449"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_095989598.1"
                     /sec_met_domain="adh_short_C2 (E-value: 1.3e-29, bitscore:
                     103.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLELRNRRALVTGSTFGIGFAIAKGLAAEGAHVFINGRKSESVD
                     KAIARIRQEVPGAQVEGVAADATTAEGAQAVFARVPAVDILVNNLGIFEPKPFFEIPDA
                     DWTRFFEANVLSGVRFSRHYAPGMRERGWGRVLFISSESALNIPTEMIHYGMTKTAQLS
                     ISRGLAMELAESGVTVNAVLPGPTKTEGVQDFLQDLAKSKGQTVEQTEADFFRTARPGS
                     LLRRFASPEEVAHLAVYLCSTRASATTGAALRVDGGLVNNIG"
     aSDomain        18224..18535
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CYFUS_RS37680_PKS_KR.1"
                     /evalue="3.20E-08"
                     /label="CYFUS_RS37680_PKS_KR.1"
                     /locus_tag="CYFUS_RS37680"
                     /protein_end="114"
                     /protein_start="10"
                     /score="25.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="LVTGSTFGIGFAIAKGLAAEGAHVFINGRKSESVDKAIARIRQEV
                     PGAQVEGVAADATTAEGAQAVFARVPAVDILVNNLGIFEPKPFFEIPDADWTRFFEANV
                     "
     gene            19044..19553
                     /locus_tag="CYFUS_RS37685"
                     /old_locus_tag="CYFUS_007450"
     CDS             19044..19553
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025892.4"
                     /locus_tag="CYFUS_RS37685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007450"
                     /product="hotdog fold domain-containing protein"
                     /protein_id="WP_157758881.1"
                     /transl_table=11
                     /translation="MPTLSSLTQSLSQLASSENLRLLWNVLRHAPGGGVLMGQLIGNMA
                     PYTGSIRPEVLSLEPGYVRVRMRDRRAVRNHLRSVHAIALMNLGEVATGLAVLSSLTGG
                     MRGIITHLEMDYLKKARGPISAECHAPATTPGERKEYDVQADLTDAAGEVVARARARWL
                     IGPAMH"
ORIGIN
        1 agctcaaggc cactgccggc gccagcaccg tgcgcgggac caggtcggcg gtggtcgcgg
       61 cctgtgcggg catcgccatc gccgcgcccg tgccgagcgc gaatgtcaga cacagcaggg
      121 accaggcacc gagccggccg gcatgtgcct gcagggcgac cagggtgacc acgaggagca
      181 tccacagctg caccccgagc aggtatcgcc gacgatcaac gatatccgcc agggtgccgg
      241 caacgagcgc gaacgccacg accggcagcg tcgtcgcgga ctgcacagcc gcgaccatga
      301 gcggtgagcc cgtccgctcc gacatgaacc aggaggcggc gacatcctgg acccaggttc
      361 cgacgttgct ggtcagaacc gccagccaga gcgcacggaa cctgggatgg cgaagcggtg
      421 cccatgcgcc aatcgccgga gcatcagaag gcatagcaca agcatcccaa cgcaccccag
      481 aagtcgcgca gcccgccgcc tggcgtcggg tggtgtgcgg cgtgatcctt gccatgacca
      541 tgcacggcac acgacgttcc gtgtgagtga gaatgccgtt gcgctcgagc gaacatggca
      601 cgggcctgcg cctgggtgcc gccctggtag cctccaaacc ggttcaccgg cgaccagtcc
      661 ggcatgggct tgggcagcga gggggcgagc gggccgaagt caccaccgcc gtgcaccacc
      721 ttgccaccca ccacggtcaa cacgctggtg atgtccttga tggcttcttc cggcacgtgg
      781 aggaagtccg aggacagcag tgcgaaatcg gcatactggc caaccttcag gatgcccttg
      841 cgatcctgct catgggagag ccacgcgctg ccgtgcgtgt acaggcgcag cgcttcttct
      901 cgttccagca ggttgtcgtc gccatacatc gacagaccgc ccacggtgcg gccggtaacc
      961 atccaataca acgccaccca cgggttgtag ctggccacgc gcgtggcatc ggtgccggcg
     1021 ccgaccggca cgcccgcctc cagcatcttg cgcaccggcg gagtgttccg ggtcgccgcg
     1081 ctgccgtagc gctccgcgaa gtactcgccc tggtacgcca tgcgatgctg gatggcgata
     1141 ccgccccgca gggcgcgcac gcgttcgatg ttgcgatcgg agatggtctc ggcgtggtcg
     1201 atgaaccagt gcagtccgtc gaagggcacc tcgcgattca ccttctcgta gacatcgagc
     1261 acgcggctga tgctctcgtc gtaggtggca tggatgcgga acggccagcg gcgctgcgcc
     1321 agcaggcgaa ccacgtcttc cagctcgccc tccatgccct gcggcagctc cgggcgcggt
     1381 tcacgaaaat cctcgaagtc cgccgccgag aagaccagca tctcgcccgc gccgttgtga
     1441 cgcagcatgc cgtcgccctg gagcggcgtc agcatccgcg accacttgtc gaagtccgcg
     1501 agctcgcccc ccttcttctg ggtgaacagg ttgtaggcga tgcgcaccgt cagctcgccg
     1561 tcggcatgca gcttctggat gatttcgtag tcttccgggt agttctggaa gcctccgccg
     1621 gcatcgatca ccgaggtgat gcccagccgg ttcagctcgc gcatgaaatg gcgggtggag
     1681 ttgagctgga actccggcgg cagcttcggt cccatcgcca acgtcgcgta caggatcagc
     1741 gcattgggtt tggccagcag caggcccgtg ggattgccgg catggtctcg ctcgagccgc
     1801 ccaccgagag gctcaggact gtccttggtg tatccgaccg cgcgcaaggc ggcgcggttg
     1861 aggagtgccc ggtcgtacag atgcaggatg aagaccgggg tctccggcgc ggcctcgttg
     1921 agctcccgca gcgtcggcag ccgcttctcc gcgaactggt gctcgctgaa gccgcccacc
     1981 acccgcaccc actgcggtgc cggtgtccgc gccacctgct ccttgagcat cgccatcgcg
     2041 tcggccagcg tgcgcacgcc gtcccagcgc agctccatgt tgtagttcag gccaccgcgg
     2101 atcagatgga ggtggctgtc attgaggccg gggatgagac gccggcctcc ggcatcgatg
     2161 atccgggtcc tggcggtggc atgcgccatc accgcggcct cttcgccgat tgccagcagg
     2221 ttgccatcgg cgacggccaa cgccgtcgcc gacgggttat cccggtccag ggtggtgatc
     2281 cgggcatttt tgacgatcat gtcggccatc ggtacaatcc tttccattcc ggcgactcga
     2341 gccggagaca atcgttatca cctacgacat ccgatggccg catggccatc aatcagtgac
     2401 cgccttcgga cgctccgaac atcgtcttgg cgtactgcaa gccgattccg tagccgccac
     2461 cgtgggtctt ggcgatgccg gtggtcaggc cgtacgtggc ctcgcgcgcc caatcgcgct
     2521 gcagctcgag caggtactgc aggctggtca tcggaaccgc accggcctgg atcatccgct
     2581 gcaccgcacg ctcgtgcgcc tcgtcggaca catcaccgca ggcatcggtg atgacgaacg
     2641 tcttgaagcc ctggtcgatc gccgacacga cgggacccac gatacacacg cccgtccaca
     2701 gtcccgcgaa caccagccgc tccttctcga aggcgttgat ctgggtgatc acctgcttgt
     2761 cttcccaggc attcatggag gtgcggtcgt agaccttcgc accaggaaac gcctcggtga
     2821 tctccgggaa caacggcccc gagaagctct tctccgcgac cgtggtcagc agggtcggga
     2881 cgcggaagcc agcggcggcc ttggagatga gcgcggtgtt gttgcgcagt tgcgcgatgt
     2941 cgatcgaatg cgtcgcgaag gtcatctgcg actggtgatc gatcaggatc aaggcatggt
     3001 cggtgggcga caggaggccc tttccgggcg tgggggaggc tttgggcggc atgggactgt
     3061 tcctcttcgg tttgggttat gccaaacaga ctagagcgtc aggactcgag aaaaaacact
     3121 cgaaagcgca ggaagcggat cacccgaatg ggggagtgaa cgcccaccgg cccgttactc
     3181 atcaacgcgg gtcttcttgc gcggcggcag ggtgacaaca cgccttccga acaaccacgc
     3241 atccaccgag tgagcgccgg gtccgaggag cgccagtgca cccgcggcga gcagctcgat
     3301 acccgcttca ggcagggtca cgccgcccat gaccatgaag tcgtagaaag agaacaggaa
     3361 gcacacgacc gcgagggtag gtgtcagaac gcccaggcag agtccgatgg ccaggagcgc
     3421 gagcatcgca ttcatcagcg gtccgccgga gaggtggggc agcagggaca gggcgaccga
     3481 caggcgcagc aacagcagtc cgaccccggg gccaccttcg ggaaacatgg agaagaggcg
     3541 ttgcaccggt ccatcttacc ccccctggtg cggcgcgatt gtatctgaga taagggagcc
     3601 cggcctcccc atttcggggg attccaacga tgtcgatgac gggtatccaa cgaccgttcg
     3661 ctggtcgagc tcaacgggac ggagccgatg tttccacgac gaagggtgat gactgcgggt
     3721 ggaacggcct cgcggggcga catgggcctc tccggccgcc cggcggaggg cgctgagcga
     3781 tgagctccac gaacccgccc attcgcatcc tgattgtcga cgatcatccg ctgctgcgcg
     3841 aagggctcag cagcatgatc gccgggcaac cggacatgaa gctggtcgcc gaggcggaga
     3901 atggagagca ggccctgcaa gccttccgcg accacctgcc agacatcacg ctgatggacg
     3961 tgcagatgcc cacgatgaat ggcatcgatg cgatcacggc gatccgcacc gagttcccca
     4021 ccgcgagaat catcatcctg acgacctaca agggcgacat gcaggcgttg cgcgccatca
     4081 aggcaggcgc gtccggatat ctgctcaaga gcatgttgcg caaggagttg gtggaaacca
     4141 tccgcagcgt gcatgcggga cgtcgccgca tcgccgcgga tatcgccacc gagatggccg
     4201 agcacgtggc ggacgacgaa ttgacggcac gggaatgtga cgtcctgcgc ctcgtggcca
     4261 gcggcagcgc caacaaggaa gtcgccgccc ggatgggcat ctccgaggag acggtcaaga
     4321 cgcacatgaa gaacgtcctg accaagctcg gcgccaagga caggacgcat gcggtggtcg
     4381 tcgcgctgaa gcggggaatc atcgatatct gagcgtggcc gcgcggcggc agcggctcgt
     4441 atccgtcgag gtagaatacc gatggtgggg acgaggctca ggggacccgt caggttctgg
     4501 cagcaggcgc tgttcctcgg actcgtcgcg gtgctcacgt tcttcgcgga cacggcgcgg
     4561 gcattcagtc aggaccgacg cctcactcag ttccaccaca cccggtggac gatcaaggaa
     4621 ggagctcccg gccagatctc cgcgatcgct cagacagaag acgggtatct gtggcttgcc
     4681 gcggccgctt cgttgtaccg gttcgagggc atccgcttcg aacggttcga gccgccctcg
     4741 ggcgatccct tctccaccat ccagaccttg tacgccccgc ccgacggtgg gctgtggatc
     4801 ggcttccagc tcggcggcgt cgcgttcctg aaagagggac acttgacccg gtatcatggc
     4861 accgagggcg caccgaccag gtcggtttcc gccttcgcca cggatcggga cggcaacgtc
     4921 tgggcctccg aaatgcgtgg aggactgttc cgtctgtccg gcacgcgctg ggaacagatt
     4981 ggagaatcct gggggtatcc gggcagcaag tcccggcacc tgttcgtgga tcgggacggc
     5041 acgctgtggg tcgccaccga gaagaccctg ttgtatctgc cgcgcggcgc gcacaggttc
     5101 gtgcccacgg acgtcagcgt cgggtgggtg ttccagttga ggcaggcacc ggatggaagg
     5161 atctggatga cggaatcggg cggtgacgtg cgaccgattc cggtgcccgg ccacggacag
     5221 acggagaatc cccccaccct gcatgtggag tcggcgggca tgttgttcgc ccgcgacggg
     5281 agcctgtggc tcaccaccct gggtgatggg gtccgccgcc tcgcccatcc cgagcgctcg
     5341 tcggccggag acgcggcgga ggtgggtggg gaggtggagt ccttcaccga gaaggatggc
     5401 ctgagcgcgg attacgcatg gccagtgctc gaggatcgcg agggcaatgt ctgggtgggc
     5461 accagcggcg ggctcgatcg cttccgcacc agctcgatgg tgctggcgga gttcccgcgc
     5521 ggttcgcacg atttcgccct gatcgcgggg aatgccggcg aggtctgggc gggtaccacc
     5581 aaccgtccgc tcatgcgctt gcacgacggc gaggtctcgt tcgagcagct cggctccccg
     5641 gtccgctccg cctaccgcga cgaagagggt gtggtctggc tgggagcgga cgacggcctg
     5701 tggcgggtgg aggacggccg cctgagtcgc gtcacgccac tgccggatcc gctcgcgcag
     5761 gtgcaggcca tgactcgcga tcgccatggc acactctggg tgtccctgac gaccggtgga
     5821 ctgatgcagt gggaggatgg ccgttggcac tcggtggagg agccgctggg tcctttggat
     5881 ggcgagagca tccacaccgc gatgaccgat ggtcgcggac gggtatggct gggccatcag
     5941 cggggcatca tcacgcgggt cgacggcgac gaggtccggc ggttcaccga ggacgacggg
     6001 ctcaggctgg gggtggtcgc cgccctgacc gccggccgcc ggtatgtgtg ggtcggcggc
     6061 cagttcggac tggccttcca tgacggtgag cgctttcgtc cactcgtcgc cgacggtgac
     6121 gaatcgttcc gcagcgtgag cggcatcatc gagcgccccg atggcagcct gtgggtgcat
     6181 gccgtgccgg gggtctttca cgtcccggcg gaggaggtcc ggcgcgcggt aggcgatccc
     6241 ggccatcgcg tgcgctatga gttgttcgac ttcctcgacg ggcttccggc caggccgacg
     6301 ctgctgcgtc cgttgcccac ggccatcgcg ggcggcgacg ggcgtctgtg gttcgccacc
     6361 agcaacggtg tggtctggat cgatcccgag cggatcgccc gcaatccgtt gcctccaccg
     6421 gtgtccatcc tctccgtgaa ggccgatggc cgccggtacg cgccagcagc ggacgtgacg
     6481 cttccgatcc atcccgccaa cctggagatc gactatgccg cgctcagcct gtccatcccc
     6541 gagcgcgtgc gtttccgcta ccggttggaa ggcgtggacg agcactggca ggacgtcggt
     6601 acgcggcgca ccgcctatta tggcaacctg gcgccggggc agtaccgctt ccacgtgatc
     6661 gcatcgaaca acgacggcgt gtggaacgag cacggcgcga gcctcgagtt cgtcgttccg
     6721 cccgcggtcc accagacctg gtggtttcgc acgctctgca tggcggccgg actgctgctg
     6781 ctctggctga tgtatctgct gcgtctgcgc caactgaccg cgaagatgcg cggccgtctg
     6841 gaggagcggc acgcggagcg cgagcggatc gcccgggagc tgcacgacac cctcctgcag
     6901 agcgtgcagg ggctggtgct ccggttgcag gccgtcgccg agcagctccc cgagcacgag
     6961 ccggcacgtc aggcgatgga gaaggccctg gatcgcgcgg acgaggtact ggccgagggc
     7021 cgcgaccggg tgatggatct gcgctcgtcc gcccacgcgg gtcgcgacct gtcggacgcg
     7081 ctcgtgcggg tcgggaagga gttggcggag aacctcccga tgtcgttccg tctggtcacg
     7141 gaaggtgtgc cacaagagtt gaacgccgcc gtgcaggtgg agatcttctt gatcggccga
     7201 gaggccctgc tcaacgcgtt ccagcacgcg ggaggcacgg ccgtggaagc agaactccac
     7261 tacgactccg acgagttgcg cgtgcggatc cgggacgacg gcgcgggcgt ggacccggag
     7321 gttctcgaaa tgggcggccg tccggggcac tggggcctcg cggggatgca cgaacgggca
     7381 gcgaggatcg gggctacatt gcaagtgtgg agccggaccg atgccggcac ggaagtggaa
     7441 ttgaaggtcc cagccgagat cgtctaccgg cggaggccga aagcggcctg gtggagcagg
     7501 ctgaaggata tcgcccgcct ggcgcgaggg agatgagagc gcgcgccgag gcggatacgt
     7561 caggcgacgg cgcctgcccg ggcacgcggc accggctggg cgtcgaggaa ggagcgcaag
     7621 gcggtcgcga agggctccgg ccgctcgaag aatgggaagt gcgagccccc ctcctcggcg
     7681 gtgaagatgc gcaactgggc gcccgggatt tgctcggcgc tccacttctg cgaggccggg
     7741 ttgacgtggc tgacctcgcc ggccatcacc agcgtcggca cgtcgatgcg tggcagcacg
     7801 tcgcgccagt cctgcatgat gtggtccagc aacagccgtg agccgaagcc gccctcgagc
     7861 ttgaggttct cctggtagag ccacgccaga tccgcgctgg agatctgttt ggtgagcatg
     7921 gagacgagga agtcgtgccg cacggccgcc gcgtcgggac cgaggacgcc cttgcagaag
     7981 gcctcggcac cggggaaatc caagatggcc cccacttcgg tcgcctcgac cttgttcaac
     8041 caggggagaa ccgtgcaggc actgggctgg tcgatgatga tgagcgaact caccttcgcg
     8101 gagccgaaca ggtcgaggta gctccacagc accgacgccc ccatggagtg gcccgcgaaa
     8161 tccgcccgct cgatccccag gtacgtcagg agttcgtcga ggtcacgcgc gagccgggcg
     8221 atgcgagcgc cgtgcggagg atggccggac tcaccgtggc cacgctggtc gtagctgacg
     8281 acacggtaat gactggcgag catggggatg acccgatcga acatcgcgcg cgactgtgac
     8341 cagccgtgca gcaataccag ggtacgctcg ctcgaactcg aacccgcgag gtgatagtcc
     8401 agttcgcatc cgtcggcggt ggtgaaggtg ctcatgatgt cttccttggg ggtgcgctcg
     8461 gttcaaggcc agagacgcca ggtccactcg caccagtagc gtgtcggaca tgggaggaaa
     8521 tcacccgaaa gcacatgcaa ggcttcaccc gaaagaggga gcgagcactc accattgcac
     8581 tccacgaaca ggaatgagag atgggacggc atgcaactcg tagaggaaga gacgtcacga
     8641 gcggccccga tgcgggtccc gaccgccccc gctcgttggc cacttctcgg acattcctgg
     8701 cccctgctct ccagaccacg agatttcctt ctctcgttgg agaaggtcgg gagtctcgtc
     8761 cgtgtctaca tcgggcagat gcccatggtg gtcatcaccg atcccgaact cacgcgtcag
     8821 gtcctgcatg acagcgccac cttcgataaa ggaggctccc tctacgagaa gctgagcgag
     8881 ctgacgggca atgggctgct cacgagccag tcggagccgc acaaacgaca gcgtcgcctg
     8941 gtgcagcccg ccttcaagaa aagttcgatc aaggactact cgtccgtcat ggccggggtc
     9001 gtcgaggtgg cgctccgcga ctgggaagat gacgccgtgg tcgacatgaa ggccgccgcc
     9061 tatcacatcg tctcccgcat cgcggcgcga tcgatgttct cggctgaaat ggccgacgcc
     9121 tccatcgcga gaatcgccga ggccctgtcc atctacctca acggcctctt cgtgcgaacg
     9181 gtggggccgg gtgtgctctt cgagcggctg cccactcctg gcaacctccg ctacaagcag
     9241 gcgctcgagg tgctgcatca ggagatcagc aggatcatct cggagtacat cgcgtccgga
     9301 gtggaacgcg aggacgtgct gtccatcctc ctgagggaaa aggacgaggg cgatggcgcg
     9361 ggactgtccc cccaggaggt ccacgatcaa gtcacgacac tgctgctggc gggaatcgag
     9421 acgtcggccg cgaccctgtg ctggtgtctg tacctgctga gccaccatcc ggacgtcacc
     9481 caacggctcc aggccgagtt ggacggtgtt ctcggtgggc gggccgcaca atgggatgac
     9541 atccccgagc tgaagcaaac acgtcgaatc gtcatggagg cgctgcgcct ctatccaccg
     9601 ggctggctct tcacccgggt gacgatgcgt gacaccgtcc tcggcgccta cccgctcccg
     9661 cggggaaccg ggatcgcgta cagcccctat ctgctgcacc gcagccccag ttccttcgaa
     9721 cagccggacc gcttcgatcc cgaccggtgg ctccccgagc gctccaaccg cctgtcgatg
     9781 aacagcttcg tccccttcgg tgggggggtt cgccgctgta tcggggagat gctcggggtg
     9841 accgaggtca tgctgaccct ggcgacgatc gcctcgcact gggaggcgcg gtgcgtgcgc
     9901 gaggggccga tcgagcccgc gccagcacat gtctcgttga tcccgaagca gttgcggatg
     9961 cgggtcacac gtcggaagag gtaacctctt gagagtccaa gtgaatcaac agtccatcca
    10021 ccagacgttg gaaacggtcg actgggggcc tccgccgccc ctcaacaagc actacccggg
    10081 gatccatcgg gaagcggatc tctggctgga gagcgtggga ctgacggaca agccgggccg
    10141 cctcgcgaag caccggagga tcgaggttcc cctgttcgcg gccatggcct atcccacagc
    10201 ctctcgcgac aacctgctcc tggcccatga ctggatggcc tggctgttcg agtacgatga
    10261 ccagttcgat gagggggacg acggtcacag caccgacagg gcccggcaat cccgggagag
    10321 cctgttgtcg atcctcgacg acacgtccac cgtggcgcgg gaggtccctc ggagaacgct
    10381 ccaatcaggg ctgagtgaca tctggtcgag actgcgggcc gtggcccctc ctggcctgcg
    10441 ggagcgcttc gcggggcatg tcgcggacta cctcgagtcc tatgaatggg agacccacaa
    10501 ccgccgcgtc gggtactgcc cggacgtcga ggagtatctg gcaaagcgac agcacacggg
    10561 cgccgcccat ccctgcttcg acctggtcgt gcccgcggcg ggaatccagt acggccgtgt
    10621 ggattggacg aatgccagga gggggcgcct cgaatacctc tcgtcggaga tcatcacgct
    10681 gtccaacgat ctcgtctcat ttccaaagga aatggagcaa ggagacgtcc acaacatcgt
    10741 gatcatcctc atgcggcggc acggacatcc ggagcaagag gcggtccttc ggacggtggg
    10801 cctgctcgag tcgcgcatcg cggacttcga gcgggaggcg agtggactgg cgcgagcccc
    10861 cctcggcctg aatgacgata cgaagcttta catccacggc ctgaaggtct ggtaccaggc
    10921 caactatttc tggtcgttga aatgccgtcg cttcatcgtc gaccaggtgg atgaggcggc
    10981 ccactgagcc gcctcatcag tggacaacct ccatgggagg cggcgaggag agcccgatga
    11041 gtcgaaccgt ggaattttcc aagaatccgt cattgggagc ggagtctcac ggctccgtca
    11101 cggcgaccac gggttcccct tccatgcccg cgaaaggagt tgcgaggaca tggcggagcc
    11161 gggaagaaaa ccacgctacg aacgaaacat ggttgtttga gttgacaaac cgacaacgcc
    11221 tgccttagag atccttccgg ctttcctctg gatttctgga cgcttccgat aatcaaggtg
    11281 tgcggtagca cgaagaaagc gacgggctgc acgcgagcac tggctcgacg gtagcggttg
    11341 ccggtgtcac gggtgcggca gggggcggcg cgtcgtcgac ggacgcgcgg tggcactcaa
    11401 catcaaggag caccgataca tgcgaaagtc gtctacgtgg ccggtgggcg gagtacgccc
    11461 gctgagggcc atggtggtgg gttgtgccct cgtagctcct ctgtccgcca tcgcgggccc
    11521 gtccgacacg aaacagccac ctgcctccgc gcgcggcgtc tcgctgcctc cggcggtgct
    11581 cgtcagtgat tcgcgagagg tctccgcggg tggagccagg ggttactcgc tcgtgacgcc
    11641 ggccgggctc gtcatccacc gcaccgagcg gcctgtcctg gcgctgcgct ccatccaggt
    11701 tcccggcacg gccatccaac tgcatacgtg gcaggaatcg cagacgaacg ggatgcgcca
    11761 gagctacacg gcctatacgc gcggcgggac ggaggcggtt ggccgtgtca gggataccag
    11821 ctacctggta cgtctggacg cggcgcagtt cgacccgctc caggtcacgc agccgctggc
    11881 cacccgtctg ctcgccgcgg atccggacaa cacgctgcac ctggtgcagt tcctcggggc
    11941 gccgctgccg gagttccgcg aggccatcga gcgccagggc ggcaaggtgt tgcgcttcct
    12001 caccgaccac accttcgtgg tggacatgga cgcggacgcg cagaagcgcg tcgcggagct
    12061 gccctacgtg cgctgggtgg ggccctacca ccccgagtac cggctggagc gcgagctgcg
    12121 ggaatccctg atggggctgg cgccggcgct ggcaccgcag cgctactcca tcatgctggg
    12181 tgagagcggc gccggacggc aggaagaggt ggccgccctg gtgcgcaagc tcggcggcac
    12241 ggtggagctc atcgagcagg gaggcctgcg cgtggaggcc acgctcaccg cggcccagct
    12301 gcgccaggtg gctcgctcca acgcggtgca gttcatcgac cggtggggtg gccccggtgg
    12361 cgtggacatg gacatcgtcc gcgacgtggg cggcgccaac tacctggagg ggctcgaggg
    12421 ctggacgggc cagggcgtgc gcggggaaat cttcgacacc gagctgctca ccacgcatca
    12481 ggagtggagc accgccccca tcatccacag cacgggcacc acgggctcgc tccacggcag
    12541 cagctgctac agcaacaact tcgcccgggg cgcgaacccg gccgcgcgcg gcatgattcc
    12601 cagcggccag ggcatcttct tccgctacag cgagtccacc cagttcggcg gcaccaagtc
    12661 ccgctacgac atcaacaagg agctcatcaa cccggccggg ccctaccgcg ccgtgttcca
    12721 gacctccagc gtgggcagcg cccagggcac cgcctacacc accatctccg ccgaggtgga
    12781 cgactacctc ttcaagcacc ccatcctcag cacacagtcg cagagcaaca cgggcagccg
    12841 gaactcacgc ccgcaggcgt gggcgaagaa catcgtctcc gtgggcgcgg tccagcacca
    12901 gaacaccgcc agccgcgcgg atgaccgctg gaactacacc ggcagcatcg ggcccgcggc
    12961 ggacggccgc atcaagccgg acctgtccta cttctacgac tccatccagt cggcgactgg
    13021 cagcggcaac gccaactaca cccagttcgg cggcaccagc tccgccacac cgcagacggc
    13081 gggccacttc ggtctgctct tccagatgtg gcacgagggc gtctggagcg gcttcggcgg
    13141 caaggcggac gtgttcgaca gccgccccca gatggccacc gccaaggcgc tgatgatcaa
    13201 caacgcctac cgctacaact ggcaggccgg cggctccaac gcggacgtcg accgctacaa
    13261 gcagggctgg ggcaccgccg acatccggcg cctctacgac cgcgccccga agacgagcgt
    13321 catcgacgag acggacctcc tcacaccgct gggtgtcaag acgtacgacg tcaccgtccc
    13381 gagcggtgag acggagctga acgtcacgct cgtcttcacc gatccgatgg gcaccgtcgg
    13441 cgcggcccag acgcgcatca acgacctgtc gctccgcgtg acggacccga acggcaccgt
    13501 ctactggggc aactacggcc tgacgacggg caggttctcc accccggggg gaacgtccaa
    13561 caccatcgac acggtggaga acgtgttcat ccagaacccc gtggccggca aatggacggt
    13621 ggaggtgctg ggcgacgaga tcgtccagga ctcccacgtg gagacgaccg cgctggacgc
    13681 ggactacggc ctggtggtca gcggtggcgt catcagtggt gggtgatgtc gacagcaacg
    13741 gctgagtagc cccgcgccac actcaccgcc catgcgggct ccggtggtgc cgacaccgga
    13801 gccccgatga acaacgtcgt caccggggag ccttcacccc acccaggtga acagggccca
    13861 cagggcgatt accgggcgcg ccgctcctgc cgctcgcgcg cctcggcctg cttgcggcgc
    13921 gaggcctcgg cgcccgtctc cggcggcacc agcgcgtggg gtccccggcc gatgaggtcc
    13981 tcccggcccg cctggatgag cgcctcgcgc gccagcggcc actgctccgg attccagtag
    14041 agcagcagcg ccttctgcag cttcttctcg cgcaggcccc gcgccgtgta caccggctcc
    14101 atcttcagcg gatccaaccc cgagtagtac atggccgtgg ccaccgacat gggcgtggga
    14161 atgaagtcct gcacctggcg cggccgcttg ccgttctgct tgagccacag cgccagctcc
    14221 accatgtcct tcagctccga gcccgggtgc ccgctgatga agtagggaat gtcgtactgc
    14281 tccttgcccg cctcctcgct cgcgcaggcg aacatcgtct ggaagcgctc gaagctctcg
    14341 atgcccggct tcttcatctt ctccagcacc cgcttcgaca cgtgctcggg cgccaccgag
    14401 agctggccgc ccacgtggtg cgcggccagt tccttcacgt actccggcga gcgctcggcc
    14461 aggtcgtagc gcacgccgct cgcgatgaag acgtgcttga tgccctcctc ctggcgcacc
    14521 tgcttcatca ggtcgatgag cggcccgtgg tccgtgtcca ggttctcgca cacgcccggg
    14581 tgcacgcacg acagcttgcg gcaacgcttc tcgatgtcct cgctcttgca cttgagcttg
    14641 tacatgttgg ccgtggggcc ccccagatcc gtgagcgtgc cgcggaagtc ccccatgcgc
    14701 cgcagggccc gcacctcgcg cagcacgctc tccgcgctgc ggctctggat gacccggccc
    14761 tcgtgctcgg tgatggagca gaaggtgcac ccgccaaagc agccacgcat cagcaccacc
    14821 gagtgcttca ccgtctcgta ggccggaatc tgctcccggt acatggggtg cggcacgcgg
    14881 ttgaacttca ggtcatacag ctcgtccatg gccaccgacg cgctgtcccc cttgcccgcc
    14941 ccgtcctcca ggggaagcgc cggcgggttg aagtagacgg cgcggttgcc gtggcgctgc
    15001 gccaggggac gcccgttgcc ggggttggtc tccatctgga agtcgcgcga catgcgcgcg
    15061 aaggcctcct tgtcggccac cacctcctcg tacgagggca gcaccaccgt cttctggtcc
    15121 gcggcgcgcc gcgcggggtc cgcctcgtgc accttcatcg cctcgtcgtt gatgaggtag
    15181 gccgtgcccc gcacgtcccg gaggtcctcg atgagctcgc cccggtcgag ccggtccgcg
    15241 atctcccaga tggggcgctc gcccatgccg aagacgagca ggtccgcctt ggcgtcgaag
    15301 aggatggcgc gccgcacctt gtcgctccag tagtcgtagt gcgcgatgcg gcgcagcgac
    15361 gcctcgatgc cccccagcac gatgggcacg tccggatagg cctcgcggca gcgctgggcg
    15421 tagacgatgg tggcccggtc cggccgggcg ttggtgcgcc ccccggggct gtactggtcc
    15481 tcggagcggt tcttcttctg cgcggtgagc cggttgagca tcgagtccag gttgcccgcg
    15541 gccaccccga agaagagccg gggcttgccc agttccttga agggctcggc cgagtgccag
    15601 tccggctggg agatgatccc caccttgaag ccacgcccct cgaggaagcg ggcgatgagc
    15661 accgggccga acgcggggtg atccacgtac gcgtcacccg tgacgatgat gatgtcgagc
    15721 tgttcccaac cccgggcctt catgtcggcg cgggtgacgg gcaggaaggg gtgggcgtag
    15781 cggagcggag tggccatgag cggagtccct cacctcccct aaccgctcag gggggcggga
    15841 agcaaacacc cgggctccaa aagtacctcc ggactcccct cccccgccac caccccctcg
    15901 ctcggctccc ccgcggacag gccggggccc tggggacacg agagaaggcg cttgagcgtc
    15961 atggcccacc tgggggacac aggcgaggat ggagcccatg accgccccgc ccaagaccat
    16021 cgtcttcgac ctcgacggca cgctggtgga ctcgctgccg gacatcatca ccagcttcca
    16081 gtacgccctg gagagccaga agctgcccgt gccctcggtc gcggaggtcc gcgccctcat
    16141 cggcctgccc ctcgaggaca tgtacgcgca cttcgcggcg cccgaccaga tccccaccct
    16201 gtgcgccctc taccgcgagc actacccccg caacttcgtc acgcgctcgc gccccttccc
    16261 cggcgccgtg gagctgctgc gcaccctgcg cgagcgcggc tacacgctcg ccatcgccac
    16321 caccaagcgc accgacatgg cccggcgctt cgtcgaggca ctcgggttga cgtccgccgt
    16381 ggaccacatc cagggcaccg acggctttcc ccacaagccc gcgccggacg tcatccagcg
    16441 ggccctggcc gcgctcggct ccgagggcct gtggatggtg ggcgacacca cccacgacat
    16501 cctcgccggt cgcgccgcgg gcctgcgcac ctacgccgtc acctggggca accacggcgc
    16561 ggatgagctc gccaccgcga agccggacga gatccaggcc gatctctcgc ggctgctcga
    16621 gcacctgccc gcgcgcgcct gacgcgcccc gcgtacgtca cgcggagtgc gccgcctccg
    16681 cctcgtggac gtgcgccttc tgctcccggt actcggagat gtgcgcgtag acgtgctccg
    16741 ggaagcgcag gtccttgtag acgttgccct cgtccgggtc ctccggattg gggatgatgg
    16801 ggaagtcctg ctgctgctgg aactgcagca ccttctccct ccggggcggg ctgtagtcgt
    16861 gcgccttcac ctgctcgatg agcgagagcg cctgtgcctc gtcgcacgcg ggatcctgga
    16921 ggagcagcca cttcagctcc gcctcgtcca ggaagtagcg tgccaccatg gcgaagacga
    16981 gccggccgaa atggccgatg tccttgcccg cctcgagcga gtccagcagg tgccgcatca
    17041 tcccgttctc gcgcagggcc tcctgcccac ccgctcccgc gcgctcacct cgtgtgtccg
    17101 tcatggctga agtccctttc catgaaaccg gtcgggccgg ttgcatctga aaacatgttc
    17161 agcacggtga cgcgaccctg cacctgcccg ccctcgtccc atgtaccgga tgcacggagg
    17221 gcgagcggga ggaggggcct tcagctcggg cgcgaggaga attccccggt cagggccggc
    17281 tcggattcgg ccgcctcctc ggcgggagac tcgggcacgg gggtggtgag tgcttcgaag
    17341 gtggactcgt actgggggtg attggtgccc agcagccgat cccacacgtt gaagtagagg
    17401 ccgaagttcc acttcatccg ctggtggtgc tggtggtggt gggtggtcgt ggtgaaccac
    17461 cggcccacgg gcgagcgcag gaagccccgc ggatacagct cgacgcccag gtgcccgatg
    17521 acgttgatga agagctggag ggtcaggaag atgaggaacg cgctgcgatg gaccggcagg
    17581 gtcagcagga tgagcggtcc gatgcccgcc tcgatgacgg cctccagggg gtggaaggcg
    17641 taggcggcga gcggcgatgg atcgtgcgac aggtggtgca ccttgtggac gtgctcgaag
    17701 atgggcttcc agtgcatgaa gcggtgcgtc cagtagaagt acgtgtcgtg caccaggagc
    17761 atcaccggaa tggacaggac gaaccacacc ggcccatggc ggtcgtcggt gtagaagcgc
    17821 gacagcccgg cctcggcgag cgcgtacatc cacacgccca ccagcccgaa gatgaccagg
    17881 gaacccattg aatagaggat ctcccggcgc gcctgcttct cgctcaccgg cccgggtccc
    17941 aaccgccggg acgagaaccg ccgcggcgtg cggcggtgga agaacacgaa cgccggaagg
    18001 gcgaacacca cgtagcgcag caggttgagg aagaacacgc ccaacgcgac gtcaatcggg
    18061 gaacgcgggg gaagcatggg catcaatggt ctccggagga acaacagcct agcgccgcgt
    18121 cccccaacaa agtatcccgg gccccccgtt gtctcccggc atcaacccca cccccttcca
    18181 cggaaattcc agcatggatc tcgaactccg caatcgtcga gcactcgtca ccggctccac
    18241 cttcggcatt ggcttcgcca tcgccaaggg actggccgcc gagggcgccc acgtcttcat
    18301 caacggccgc aagagcgagt cggtcgacaa ggcgatcgcg cgcatccgcc aggaagtgcc
    18361 cggcgcccag gtggagggcg tggcggcgga tgcgaccacc gccgagggcg cccaggcggt
    18421 gttcgcccgc gtgcccgcgg tggacatcct cgtgaacaac ctgggcatct tcgagcccaa
    18481 gcccttcttc gagattccgg acgccgactg gacgcgcttc ttcgaggcca acgtgctcag
    18541 cggcgtgcgc ttctcgcgcc actacgcgcc cggcatgcgc gagcgcggct ggggccgcgt
    18601 cctcttcatc tccagtgagt ccgccctcaa catccccacg gagatgatcc actacggcat
    18661 gacgaagacg gcccagttga gcatctcgcg cgggctcgcc atggagctgg cggagtcggg
    18721 cgtgacggtg aacgccgtgc tgcccggccc cacgaagacc gagggcgtgc aggacttcct
    18781 gcaggatctg gcgaagtcca agggccagac ggtcgagcag accgaggcgg acttcttccg
    18841 caccgcgcgt cccggctcgc tcttgcgccg cttcgcctcg cccgaggagg tggcccacct
    18901 ggccgtctac ctgtgcagca cgcgggcctc ggccaccacc ggcgccgcgc tgcgcgtgga
    18961 tggcggcctc gtcaacaaca tcggctgaag cacggcgggg aggcagcccc tccgggcccc
    19021 ggggatgtta tgtcccaggg gccatgccca ccctctccag cctgacccag tccctgagcc
    19081 agctcgcctc ctccgaaaac ctgcgcctcc tgtggaacgt gcttcgccac gcaccgggag
    19141 gcggtgtcct gatggggcag ctcatcggca acatggcacc gtacacgggc tccatccgcc
    19201 cggaggtgct ctccctcgaa cccggctacg tccgggtgcg catgagggat cggcgcgcgg
    19261 tgcgcaacca cctgcgctcg gtgcacgcca tcgcgctgat gaacctgggc gaggtggcca
    19321 ccggactggc ggtgctgtcc tcgctgaccg ggggcatgcg cggcatcatc acccacctgg
    19381 agatggacta cctgaagaag gcgcgcggcc ccatctccgc ggagtgccac gcgcccgcga
    19441 ccactcccgg cgagcgcaag gagtacgacg tccaggcgga cctcaccgac gcggcgggcg
    19501 aggtcgtggc ccgagcccgc gcccgctggc tcatcggccc cgccatgcac tgacccggtg
    19561 gccggcgttc gtctaggatg aacggcacct catgcctcca agggttcacg catgatcgtt
    19621 cgcactctcc tgctcaccct cgcggtcgtc gcgaccattg gttgcggctc cccttcccaa
    19681 accggacccg atgccgggca tgacatcgac gcgggcaacc ctggcacccc ccaggatttc
    19741 tactcgtcgt tcgaggacgc ggacccacag cccgcctgga gctccacggt cgaactcgac
    19801 gcgaaggggc agaagaagtc ctccgggatc accggggagc cggacacgcg gattcgcggc
    19861 aacatcatgg cgcaggtgcg ctcggtgacc gccagcagcg agaaccctcc cgaggagagc
    19921 gtggcccgcc tcaccgacgg ggagctgacc tccaagtggc tggcgtacca gaacacgggc
    19981 tgggtgcagt gcgagctcgc gcggcccctc gccgtgaagc gctacgccct ctcctccgcc
    20041 aacgactcac ccgagcgaga ccccgccacc tggacgctcg agggctcgca ggacggaacg
    20101 agctggaccg cgctcgacca gcgcagcaac gagtcgttca ccacccgcct cgagacccgc
    20161 acctacgagt tcaccaacac caccccctat ccctattacc ggctcaacat caccgccaac
    20221 cgcagcggca ccaccctgca gctcgccgag ttccagctct ccgatggcga tgacgcgccg
    20281 ccgccagtga ccgacatgaa gagcgcggtc ggcaacggcc ctggctcttc gtggaactcc
    20341 aagatcggca ccgggttcac cggcacgcac gcgctgcgct tcgcgggcgc ggtcaccgcg
    20401 agcggccgcg gctacgccta caacaagctc ttcgacgtca acatacgggt cacgccgacg
    20461 acggagctgt cgtatctgct cttcgtcgac ccggcgacga acaacccgaa cttcccgagc
    20521 acctacgcgg cgctcgatct cgccttcgac gacggcacct acctgagcga gctgaacgcc
    20581 gtggaccaga accacgcggt gctgagcccc acgggccagg gcgcttcgcg cacgctctac
    20641 cccaatcagt ggaaccacaa ggtctcacgc atcggtgacg tcgccgccgg caagacgatc
    20701 aagcgcatcc tcatcggcta cgaccaaccc aacggcccgg tttcgagctt cggcggatgg
    20761 atcgacgacg tgcggatcac ggcctcgccc gtgcacgtga cgcccacgca tctgtcggac
    20821 tacgtgacca ccctgcgtgg cacccactcg aacgccagct actcgcgcgg cagcaacttc
    20881 cccgcgacgg ccatcccgca cggtttcaac ttctggaccc cggtgaccga cgcgagttcg
    20941 ccgaactttc tctacgagta ccaccgccgc aacaacgtgg acaatcg
//
