LOCUS       NZ_CP022098            21596 bp    DNA     circular CON 17-FEB-2024
DEFINITION  Cystobacter fuscus strain DSM 52655 chromosome, complete genome.
ACCESSION   NZ_CP022098
VERSION     NZ_CP022098.1
KEYWORDS    RefSeq.
SOURCE      Cystobacter fuscus
  ORGANISM  Cystobacter fuscus
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Cystobacter.
REFERENCE   1  (bases 1 to 12349744)
  AUTHORS   Rupp,O., Goesmann,A. and Sogaard-Andersen,L.
  TITLE     Sequencing and comparative analysis of myxobacterial genomes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12349744)
  AUTHORS   Bruckskotten,M., Treuner-Lange,A., Rupp,O., Goesmann,A. and
            Sogaard-Andersen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2017) Department of Ecophysiology, Max Planck
            Institute for Terrestrial Microbiology, Karl von Frisch Str. 10,
            Marburg, Hessen 35043, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 09-AUG-2016
            Assembly Method                   :: Celera Assembler v. 8.1
            Expected Final Version            :: yes
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/17/2024 10:04:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,093
            CDSs (total)                      :: 10,016
            Genes (coding)                    :: 9,906
            CDSs (with protein)               :: 9,906
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 26 of 110
            Pseudo Genes (incomplete)         :: 101 of 110
            Pseudo Genes (internal stop)      :: 1 of 110
            Pseudo Genes (multiple problems)  :: 17 of 110
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:24:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9166690
            Orig. end                         :: 9188286
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21596
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="46"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21596
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21596
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11596](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11596)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            1256..1549
                     /locus_tag="CYFUS_RS37105"
                     /old_locus_tag="CYFUS_007332"
     CDS             1256..1549
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002618031.1"
                     /locus_tag="CYFUS_RS37105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007332"
                     /product="DUF2934 domain-containing protein"
                     /protein_id="WP_095989498.1"
                     /transl_table=11
                     /translation="MARAQAKTNNSNKSSSKKPEAPPPAATPITNVAPVAQAAPAKKET
                     PAVQAAPAPTRSRPSAEQISRRAYELFLARGGEHGHHDEDWVQAERELQLGR"
     gene            complement(1553..2644)
                     /locus_tag="CYFUS_RS37110"
                     /old_locus_tag="CYFUS_007333"
     CDS             complement(1553..2644)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624918.1"
                     /locus_tag="CYFUS_RS37110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007333"
                     /product="hypothetical protein"
                     /protein_id="WP_095989499.1"
                     /transl_table=11
                     /translation="MSTSAARRALALLPPHATTGIGSLPYTQLEPGLRTAFALDIPFLP
                     QLPVGRPAEFMIPQALEGLPGLGFDEAGRCAVELAAWSAGREAFEARLEAALSSGELAS
                     FEPSPEASLAWRPFLEEVERRALAFAKAQLAGPFTVNLATRTSEGRAALEEPGLDTAIF
                     RLTRARARAMVKALRRAGTTPLFFLDEPGWAAFSRADPWHQRASHELRLLVETLQREGA
                     LVGVHCCGNTDWASLLDAGLDVLSLDVRLSLDAVLEETGPLARFLDSGATLSLGIIPTD
                     LASTYDVGELVDAVEVSLEAALPPGHSLEQMGGQMLLTPACGLALRTGVEAERVLEQLA
                     EARRRLLDARAARPSPIRPSLVS"
     gene            complement(2641..3540)
                     /locus_tag="CYFUS_RS37115"
                     /old_locus_tag="CYFUS_007334"
     CDS             complement(2641..3540)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (21-276). E-value: 6e-31.
                     Score: 99.9. Matches aSDomain:
                     nrpspksdomains_CYFUS_RS37115_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="CYFUS_RS37115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007334"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_095989500.1"
                     /sec_met_domain="PF00561 (E-value: 1.4e-23, bitscore: 83.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.4e-21, bitscore:
                     77.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTRTLDIDGPVHFMDFGGSGPTLVLVHGLGGSHHNWMGVGPRLA
                     RHARVVAVDLAGFGLTPLAGRSAALPANQVLLDRFIQKVSPSAPVILVGNSMGGAISVL
                     QTARNPGRVSGLVLVAPAQPRAEDSRMERNVLSLFLLYSIPGVGEFFVRRRSARMTPEA
                     LAREQLALCCRDIGRFPEELVRAHLEFARERHARMPWSHEAFLQAARSLVSLLLRKSRF
                     RELERSIRVPTLLVQGSDDQMVPVANSRELARVRPDWTYVEYPDIGHTPMMERPELFLE
                     TMERWFEGPGRVALDAAT"
     aSDomain        complement(2713..3477)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CYFUS_RS37115_Abhydrolase_1.1"
                     /evalue="6.00E-31"
                     /label="CYFUS_RS37115_Abhydrolase_1.1"
                     /locus_tag="CYFUS_RS37115"
                     /protein_end="276"
                     /protein_start="21"
                     /score="99.9"
                     /tool="antismash"
                     /translation="PTLVLVHGLGGSHHNWMGVGPRLARHARVVAVDLAGFGLTPLAGR
                     SAALPANQVLLDRFIQKVSPSAPVILVGNSMGGAISVLQTARNPGRVSGLVLVAPAQPR
                     AEDSRMERNVLSLFLLYSIPGVGEFFVRRRSARMTPEALAREQLALCCRDIGRFPEELV
                     RAHLEFARERHARMPWSHEAFLQAARSLVSLLLRKSRFRELERSIRVPTLLVQGSDDQM
                     VPVANSRELARVRPDWTYVEYPDIGHTPMMERP"
     gene            3608..4690
                     /locus_tag="CYFUS_RS37120"
                     /old_locus_tag="CYFUS_007335"
     CDS             3608..4690
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS37120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_007335"
                     /product="hypothetical protein"
                     /protein_id="WP_095989501.1"
                     /transl_table=11
                     /translation="MAEFPETTSAALKLLERARHHVRTRSRNEAYYQAGDRFSELFLGR
                     TFQVEPDYYRAVGTDYSAIDWLYEELAQGAALTRQTLDAVTEQLQEMTRPEPARAALGP
                     LQAALHSPSCALLDVCRALLGAITVLGQDTLGARGVPAALVQDWLELWSDRLWRQNSQQ
                     ARLALLIQVMRAAPEDRPGRLAALGDEQDALSAQGTDFEQGVHEYLERYAETGASSVAL
                     AGGLPFARALTPRDLEKLLGVLREDSDFLGGVARLLRFAQDVRFDPSEPLNSGVMGYAA
                     EHRQRLTDIDATRLPREELDTRLRQVWTDNSARIRRELDAVVASLGDEPLRPLLQGFVQ
                     SVWAVASRLTDAGHDPRPGP"
     gene            complement(4750..5337)
                     /locus_tag="CYFUS_RS37125"
                     /old_locus_tag="CYFUS_007336"
     CDS             complement(4750..5337)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624921.1"
                     /locus_tag="CYFUS_RS37125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007336"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_095989502.1"
                     /transl_table=11
                     /translation="MSPPGPRGTSQERGRQRRARLIEGVTHVLRTGGLQAVSARSVADA
                     AEVPLAAVTYYFSSLEELIAETLAEMLRQWVEQVRRTTRLARAHPEKADLARWVTQAML
                     PSGGPGAIQAHYELLVACGRRAAFSAVLARGRADLDEALAELIAAALPGGTRLPSPQLV
                     LAVLDGAVVSALSEGSPVDTTVQARLDELLRA"
     gene            complement(5337..5660)
                     /locus_tag="CYFUS_RS37130"
                     /old_locus_tag="CYFUS_007337"
     CDS             complement(5337..5660)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002615873.1"
                     /locus_tag="CYFUS_RS37130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007337"
                     /product="multidrug efflux SMR transporter"
                     /protein_id="WP_002624922.1"
                     /transl_table=11
                     /translation="MAWFVLMVSGVLESGWALALKKSEGFTQPVPSVVFLVLAAMSFGG
                     LAWAMKSLPAGPSYAVWTGIGAALTAVLGILLFGESVSGVKLASIGFIVIGVIGLALSG
                     GGH"
     gene            complement(5762..6349)
                     /locus_tag="CYFUS_RS37135"
                     /old_locus_tag="CYFUS_007338"
     CDS             complement(5762..6349)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011552932.1"
                     /locus_tag="CYFUS_RS37135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007338"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_095989503.1"
                     /transl_table=11
                     /translation="MYTSRPSDPKTSTRQRDADRTRAALLSAAQTLFSTRGFANTGVRD
                     VAELAGVNSSLVNRYFGSKQGLYRETLEQVLDITPMLQGDRRRFGENVVSIFLGVQDSP
                     GPLMMLILSAADPEAHATSVELLHKKAIEPLARWLGPPDAEGRAARLNILWNGFLMSWR
                     LLPLPQLAEVRHSSTRRWLEAAIQAIVDEGER"
     misc_feature    6381..6396
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.49"
                     /tool="antismash"
     gene            6444..8261
                     /locus_tag="CYFUS_RS37140"
                     /old_locus_tag="CYFUS_007339"
     CDS             6444..8261
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002643436.1"
                     /locus_tag="CYFUS_RS37140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007339"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_198316270.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.4e-09, bitscore:
                     36.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATKKGEVSFSPEALREKYRLEREKRLRPDGNTQYIPLKGVFAD
                     FDKDPYVEPGFTRPALTEKIDVLIVGGGFGGMLAGARLRQAGVDSFRIVEKGGDFGGTW
                     YWNRYPGAACDVESYIYLPLLEETGYMPKEKYAKAPEIFAHCQRIGRHFDLYKAALFQT
                     LVQTMDWDEDTRRWNITTDRGDKLAARFVIIAGGILHKAKLPGIPGIESFKGHCFHTSR
                     WDYAYTGGSPTSSMTRLADKRVGIIGTGATSVQAIPQLGASAKQLYVFQRTPSGVGVRG
                     NQPTDPEWVKTLEPGWQQERIRNFTAIVSGRKQDVDLVRDGWTYIFQDTATQQAQTPQE
                     AAEFRQLADFRKMEEIRARVDAIVKEPATAEALKPYYNQLCKRPCFHDEYLDTFNRPNV
                     QLVDTEGKGVERITPTGVVVKGKEYEVDCLIYASGFEVSLDYTGTLGFDIRGRGGRSLR
                     DSWADGPATLHGMHSRGYPNLMMFSVIQSGHAINFVHILDEQSQHAAYIIERCVKRGIE
                     VIEPSEQAQQQWWELILGRLMTTSPVFGGPECTPGYYNNEGVKMGPNAMRYASFGGDTL
                     AFIDVLRTWRQGEQLAGLELTRGEVSSTP"
     gene            8270..9922
                     /locus_tag="CYFUS_RS37145"
                     /old_locus_tag="CYFUS_007340"
     CDS             8270..9922
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020478805.1"
                     /locus_tag="CYFUS_RS37145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007340"
                     /product="SMP-30/gluconolactonase/LRE family protein"
                     /protein_id="WP_095989504.1"
                     /transl_table=11
                     /translation="MSRFLSKSLAACLLMAGGQVLAAPPKTYRQEVVVAGSHFQGVHGL
                     VVDGKGHLLASNLLGRTVHSVDLGTGAVSTLVGPPLGGADDVTLGPDGSVYWTGFFTGE
                     LMRRTPDGKTRVIARNLPGLNSLAFRRDGRFYVTQLGRGDDALWEVDPSGKKPPRLAIA
                     RPGFLNGFEFGPDDKLYGPILLKGQIARVDVDTGSIEAVAEGFAMPVAVNFDARRENLY
                     VVDSARGELVRVRLPTGAKEVVAKLPTGLDNLAVGPDDLVYVSNMVDNDIRVVNPADGS
                     VRLLVESRLAVPSGLAVAPDDPEEQLYVADVYALRRVGGRDGKITQTTRVLSSPLNFPM
                     NVSLSAKHVVLSTAYLGDRSSVQVLDRTTGDILRTIPNANGVQAALELADGTLLVAEAT
                     TGRLVRVDTAEPAGTTVLAEGLEGPVGLAADTEAEEPGVYVTEVRSGKVTRVRLSDGAR
                     RTVAKGLKAPEGIARHPDGGLIVAEVGRKRLVRIEPATGRLSVIASGLRIGVPESAGLP
                     PGYLPTGVAVGGSGTIYLTSDIESALYRFVPVP"
     gene            complement(10001..11596)
                     /locus_tag="CYFUS_RS37150"
                     /old_locus_tag="CYFUS_007341"
     CDS             complement(10001..11596)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.4"
                     /locus_tag="CYFUS_RS37150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007341"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_198316272.1"
                     /sec_met_domain="T2TS (E-value: 7.5e-75, bitscore: 251.6,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRIRDVAMELVPSQSIRVVEGGIQELLFKELQSLLSKTGHGGGL
                     MSPSIYDSAQVLRILSPAESASSPVVDWLLSQQRADGGWGEPIKPMHRDIPTMSAILAL
                     RRFPQHPRTHEACEAGVRFLRAQAPHWATLHPEELPVAAEILVPALLNQLGLGEAQLPR
                     TPYAQLMALGERKRKIIAKLPVTPGVPWLHVWETWGQEPTANLIDGAGSVGHSPSATAA
                     WVKAASGRPELTPFVDRAREYLRESGLSTASSTPGLVPVGGPHNYFEQSFVLYALLMGG
                     VLQEPRLAPYVNSVLGDLTRALGPNGIGMSDYFLQDGDDTSAVVAVMHAMGLPVDPAVL
                     YRFKRDDHFIAYPGEMQSSPTLTARCLHALMLLGQDSDELAPFQRYLLERQEPSGRWSF
                     DKWSRSWLYTTFHSVVGLVGSPHTDAVRRALESVLSAQLPDGGWSSDGRSNMTETSYAV
                     LMLGFLERHGLHHHGISPALDRASRWMLQNYTPGAPAEGKVKCWISKELYRMERIDTAF
                     ELCALLMMQRRQYE"
     misc_feature    11702..11715
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.98"
                     /tool="antismash"
     misc_feature    11703..11716
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.37"
                     /tool="antismash"
     misc_feature    11826..11839
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.18"
                     /tool="antismash"
     misc_feature    complement(11827..11840)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.49"
                     /tool="antismash"
     misc_feature    complement(11833..11842)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.11"
                     /tool="antismash"
     gene            12409..13284
                     /locus_tag="CYFUS_RS37155"
                     /old_locus_tag="CYFUS_007342"
     CDS             12409..13284
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002643433.1"
                     /locus_tag="CYFUS_RS37155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007342"
                     /product="patatin-like phospholipase family protein"
                     /protein_id="WP_095989506.1"
                     /transl_table=11
                     /translation="MAAHTLQQTLHGKRFGLVLSAGYFGFFGHAGFLKGLAATGLRPAA
                     YAGTSSGGLVAAYAAAGLSEDAIEELVLQQTRESFWDPDPIGAVFNALPREGHGATGLL
                     KGERFRKLLERTLPVRTFEELPHPLLLTSANLTQGTHEVFTSGELVPRVHATCAYPGLF
                     RAVRVGRDLYWDGGLVDKAPALSLRESAFGKELDAILVHYLPSRTRKMLGGPMAYAQGI
                     AAGSAALRRDHFQLQLALLKERGFPVYVMVSNLPPVSPTQMERGFDALHQARLSAERAF
                     ARPPVPFEEA"
     gene            complement(13308..13748)
                     /locus_tag="CYFUS_RS37160"
                     /old_locus_tag="CYFUS_007343"
     CDS             complement(13308..13748)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002618028.1"
                     /locus_tag="CYFUS_RS37160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007343"
                     /product="CoA-binding protein"
                     /protein_id="WP_095989507.1"
                     /transl_table=11
                     /translation="MSYEQNLIEDEEGIRALVRGARRVAVLGIKTEQHSGQPAFYVPEY
                     LAQAGVDVVPVPVYYPEVTHILERPVFRRLVDIPGDIDLVDVFRRPQDIDQHVDDILAK
                     KPKAVWFQSGIRNDAAARRLAEAGIRVVQDRCLMVDHRRYAR"
     gene            complement(13745..14650)
                     /locus_tag="CYFUS_RS37165"
                     /old_locus_tag="CYFUS_007344"
     CDS             complement(13745..14650)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS37165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_007344"
                     /product="hypothetical protein"
                     /protein_id="WP_095989508.1"
                     /transl_table=11
                     /translation="MRTFSSFFLLLLAAPVTACHRDIPSLNPPPAAAPPLRPLFLPPDD
                     SLLTETVRTSLRHGSAPDAREAEMTTVSSFSAEQDSWVLTQRVTRSRYLQEGQPVESLV
                     DTVLQRAVLRLRLAADGTYVRLVEPEAVLAAIREVAPKGLDVTPLERFFAPDALEARTR
                     GEWEVKYGGIYGRAWVPGQRGYVVGTLPVGGREVTYLLERTLTGTRLTEQGEALVFSLR
                     CLAQPGEASPQAVRDTLRLAGDPPLTPGVECDGEQLLGKGRFLPVRRGFTLRASLDGET
                     WTWATQSTLESVRALEEEQR"
     misc_feature    complement(14765..14780)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     misc_feature    15678..15692
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.75"
                     /tool="antismash"
     misc_feature    15705..15719
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.98"
                     /tool="antismash"
     gene            complement(15958..17070)
                     /locus_tag="CYFUS_RS37175"
                     /old_locus_tag="CYFUS_007346"
     CDS             complement(15958..17070)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002643430.1"
                     /locus_tag="CYFUS_RS37175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007346"
                     /product="glycosyl hydrolase"
                     /protein_id="WP_232537016.1"
                     /transl_table=11
                     /translation="MTPSPSPTAQKVYGLLVDLENGARAGNRRTIIGQHCEAQKEIHQE
                     GSYAGAYYDKVTQLSGGKRPAFVEFDLGPGWYQSSFNEDATAWRATFNGVGFLKDRWTY
                     GDGLVGLGFHQPYPGSPVKSFENTLVETATNASGQRVNLDDAWFKRVVDWQNNTAEYQT
                     LLRDLSWAANRLQPLKDAGVPVLFRPYHEMNKRSGRFWWANRDPALYKQLWSIIFNYMT
                     KTRGFNNLIWVWSPYAWDGTYGGDPWNYYPTEGADIVAVDIYSGNPYLPGRYYTDLAGY
                     NKPRMLAENDKMPVRWDKNVSEIDARPWVIYSIWGDTVIRDVSGSGTANAWNVENNYQA
                     IKNTYAYEKILTGGQQPPNGTANYNWWSVH"
     gene            complement(17408..17725)
                     /locus_tag="CYFUS_RS37180"
                     /old_locus_tag="CYFUS_007347"
     CDS             complement(17408..17725)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013938570.1"
                     /locus_tag="CYFUS_RS37180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007347"
                     /product="DUF2795 domain-containing protein"
                     /protein_id="WP_095989511.1"
                     /transl_table=11
                     /translation="MAFGQGENPARSITPHLDSVDYPARREHLVEAAEDNGAGVDIINV
                     FKALPREEYLSREEVMRDLAEAARRFANGGLRDDDGVVRDRRNIGRDLVEGASDDTSRH
                     P"
     gene            17947..18225
                     /locus_tag="CYFUS_RS37185"
                     /old_locus_tag="CYFUS_007348"
     CDS             17947..18225
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002643428.1"
                     /locus_tag="CYFUS_RS37185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007348"
                     /product="hypothetical protein"
                     /protein_id="WP_095989512.1"
                     /transl_table=11
                     /translation="MTEESGREMLDIASKLFEQMLTQQRAKVLRLAREVVPNITPEELR
                     NPHDFPKLKEHPTFEFEDGLLSGLISAQMALYAEIKGRLLPPEPPGQ"
     gene            18312..19136
                     /locus_tag="CYFUS_RS37190"
                     /old_locus_tag="CYFUS_007349"
     CDS             18312..19136
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013938567.1"
                     /locus_tag="CYFUS_RS37190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007349"
                     /product="transglutaminase-like domain-containing protein"
                     /protein_id="WP_095992462.1"
                     /transl_table=11
                     /translation="MARERLVSALAADPPRLDLAALAIATLNQPHLDAAACLHTLDALA
                     ARVQLEMERHAGHGEVLAGLTALRHVLADIEGFRGNEDDYHSPENSFLDLVLERKVGLP
                     ISLSVLYLEVARRAGIPLYGVSFPGHFLVACSAGDHKLVVDPFHEGEILTEEGCKQLLE
                     RVAPQLRFNPSMLSPAPVELIAYRMLSNLRRVYLERSDYERGLAVVDLLLMLAPNHPGE
                     LRTRAALLANLGAYRAALKDVERCLELSPDAPDRERLEMTVRELRERAELLN"
     gene            19141..19695
                     /locus_tag="CYFUS_RS37195"
                     /old_locus_tag="CYFUS_007350"
     CDS             19141..19695
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002643426.1"
                     /locus_tag="CYFUS_RS37195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007350"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_095989513.1"
                     /transl_table=11
                     /translation="MRPLPPWPRLRRGLEHDYTILTVRQDIVADPRTSQEHPRVRIDCG
                     DWVNVVAVTREDQLVLIRQYRFGISAVTLEVPGGIVEPGEDPALAAARELEEETGYVAG
                     RVVALGSVHPNPALQGNRCHSYLALDCVKAHEGNPDAGEDIRVELHPREAVPRLILEGS
                     ITHSLVVVAFYLEHLRAAAPR"
     gene            complement(19724..20737)
                     /locus_tag="CYFUS_RS37200"
                     /old_locus_tag="CYFUS_007351"
     CDS             complement(19724..20737)
                     /NRPS_PKS="Domain: Abhydrolase_1 (76-196). E-value:
                     2.7e-11. Score: 35.5. Matches aSDomain:
                     nrpspksdomains_CYFUS_RS37200_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="CYFUS_RS37200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007351"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_157758877.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.3e-11, bitscore:
                     43.4, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.3e-06, bitscore: 27.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSTVRWMSMWMALVVAGLCLVPARAAAVDADAETGAWGGIKVER
                     RTFPVRLSNGRVYNLVGYLYYQGSLKNKPVQILVHGITYNHNYWDLPEINRQDYSYARY
                     MARQQYAVLALDLLGTGESDKPNGDFLDLSESASSLHQVVQRLKATAARNTFEKILYVG
                     HSNGALTITYAQAYYRDADAVVLTGWLNTYHPLPVGDEVFGPLLEQGPYVQVPPELRTA
                     LFYDPNRGHVDPAVIAYDNTEADFVPRGQLVDLFTLLKNPEPIPAEKITVPIMVQLGEF
                     DAVAPAAYAAQEARAYPRSPYVFVDKVDDVGHAVNGHRNRLRSWAMISLWLRLVGC"
     aSDomain        complement(20150..20509)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CYFUS_RS37200_Abhydrolase_1.1"
                     /evalue="2.70E-11"
                     /label="CYFUS_RS37200_Abhydrolase_1.1"
                     /locus_tag="CYFUS_RS37200"
                     /protein_end="196"
                     /protein_start="76"
                     /score="35.5"
                     /tool="antismash"
                     /translation="ILVHGITYNHNYWDLPEINRQDYSYARYMARQQYAVLALDLLGTG
                     ESDKPNGDFLDLSESASSLHQVVQRLKATAARNTFEKILYVGHSNGALTITYAQAYYRD
                     ADAVVLTGWLNTYHPL"
     misc_feature    20773..20786
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.13"
                     /tool="antismash"
     misc_feature    20820..20836
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.97"
                     /tool="antismash"
     misc_feature    20826..20840
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.99"
                     /tool="antismash"
     misc_feature    complement(20866..20879)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.43"
                     /tool="antismash"
     misc_feature    20869..20885
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.32"
                     /tool="antismash"
     misc_feature    20870..20879
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.58"
                     /tool="antismash"
     misc_feature    20872..20885
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.46"
                     /tool="antismash"
     misc_feature    20872..20885
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.19"
                     /tool="antismash"
     misc_feature    complement(20873..20886)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.42"
                     /tool="antismash"
     misc_feature    complement(20874..20887)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.28"
                     /tool="antismash"
     misc_feature    complement(20875..20888)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.79"
                     /tool="antismash"
ORIGIN
        1 ctcccgcaag cgcgcgccct cccccacccc actcctcatc gagcccttgc gccgcgaagc
       61 cctgcgcgag ggcctgctcg cctggtacga ccggcagaag cgcgacctgc cctggcgccg
      121 cacgcgcgat ccctacgcca tctggctcag cgaggtgatg ctgcagcaga cgcaggtggc
      181 caccgtcatc ccctactggg agaggttcct ccagcgcttc cccaccgtgg cggcgctcgc
      241 caccgcgccg ctgccggacg tgctcgccgc gtggcggggg ctcggctact actcgcgcgc
      301 gcgcaacctg cacctggccg cccaggacgt ggtggcgcgc tacggcggca agctgccctc
      361 caccgccgcc gagctgctca ccctgagagg ctttggccgc tacaccgcgg gggccgtggc
      421 ctccatcgcc ttcggcgagc ccgcgcccct ggtggatggc aacgtggccc gcgtcttctc
      481 gcgcctcttc gaggtggagg gcctcccggg agaccgcgtg cgcgaggccc ggctgtgggc
      541 gctcgccacc gagctcgtct cccccgagcg gcccggagac ttcaaccagg ccctcatgga
      601 acacggcgcc accgtctgcc ggccggacaa cccactgtgc ctcctgtgcc ccgtgcgcga
      661 ggactgtctc gcctggcgtc acggccgcgt gaacgagctg cccccggcca aggtgcgcgc
      721 cccccccaaa cggatgacac tcgccctggc cgtctgggcg cacgagggtc gactcctgct
      781 cgcccggaga gaagagaagg gactcttcgg tggcttgtgg gaattgcccg ccgcggagat
      841 cgaagcggac acgcccgact cggagtccgc tggcaagctc acccaggcgc tcggcacgcc
      901 ggtgcgggtg gaggccgcgc tcggcaccgt gcgccgccag ctcacccacc gcagcctcac
      961 cctccgcctg ttgcgcgtga cgggctcgaa ccaccccacg cgcgctcccg ccttccgcga
     1021 gctgcgctgg tgcacccccg aagaagcctc ctcgctcggc atgagcaccg ccatgcacaa
     1081 ggcactcgag gccgcgctcg aggccggcgt gctcccggcc tgagccgctc tgtcggttag
     1141 ccgacaagca cggctcgagc gtgtcgcatc gatgacgatc gttccaggga tcgatgcctc
     1201 gcgcacgaag agctgccaat gctgtcggca gccgtttttc gacccgagga ttcccatggc
     1261 acgcgcacag gccaagacga acaactccaa caagtcctcc tccaagaagc cggaggcccc
     1321 gccccccgcc gcgacgccca tcacgaacgt ggcccccgtg gcgcaagccg cccccgcgaa
     1381 gaaggagacc cccgcggtgc aggccgctcc cgccccgacc cgtagtcgcc cctccgcgga
     1441 gcagatctcc cgccgggcct acgagctgtt cctcgcgcgc ggcggggagc acggccacca
     1501 tgacgaggac tgggtccagg ccgagcgcga gctgcagctc ggacgctgaa gctcagctca
     1561 cgagcgaggg gcggatcggt gacggccggg ccgccctcgc gtccaggagc cgacgccgcg
     1621 cctccgcgag ctgttcgagg acacgttcgg cctccacccc ggtgcgcagg gccaggccgc
     1681 acgcgggcgt cagcaacatc tggccgccca tctgttcgag cgaatgaccc ggaggcagcg
     1741 ccgcctcgag tgacacctcg accgcgtcca ccagctcccc cacgtcgtag gtggacgcga
     1801 ggtccgtggg gatgatgccc aggctcagcg tcgcccccga gtccaggaag cgcgccaggg
     1861 ggcccgtctc ctccagcacc gcgtccagcg acaaccggac gtccaacgac aacacgtcca
     1921 gccccgcgtc cagcaggctc gcccagtccg tgttgccgca gcagtgcacc cccaccagcg
     1981 cgccctcgcg ctgaagcgtc tccaccagca gccgcagctc atgcgaggcc cgctggtgcc
     2041 agggatcggc acgcgagaag gccgcccatc ccggctcgtc caggaagaag aggggcgtcg
     2101 tccccgcgcg ccgcagggcc ttcaccatcg cccgcgcgcg cgcccgcgtc agccggaaga
     2161 tcgccgtgtc cagccctggc tcctccagcg ccgccctgcc ctcgctcgtg cgcgtcgcca
     2221 gattcaccgt gaagggaccg gcgagctgcg ccttggcgaa ggcaagtgcg cggcgctcca
     2281 cctcctccag gaagggacgc caggcgagac tcgcctccgg cgagggctcg aaggacgcca
     2341 gctctcccga ggacaacgcc gcctccagcc gcgcctcgaa ggcctcgcgt cccgcggacc
     2401 atgccgcgag ttccacggcg caccgccccg cctcgtcgaa ccccaggccc ggcagcccct
     2461 cgagtgcctg gggaatcatg aactccgcgg gtctgcccac cggaagctgg ggcaggaagg
     2521 ggatgtccaa cgcgaacgcg gtccgcagac ccggctcgag ctgggtgtac ggcaggcttc
     2581 cgatgcccgt ggtggcgtgg gggggcagca gcgcgagggc acggcgggcg gccgacgtgc
     2641 tcatgtcgcc gcgtccaggg ccacgcggcc cggcccctcg aaccaacgct ccatcgtctc
     2701 gaggaacagc tcgggacgct ccatcatcgg ggtgtgtccg atgtcggggt actccacgta
     2761 ggtccaatcc ggacggaccc tggccagctc gcgcgagttg gccaccggca ccatctgatc
     2821 atccgagccc tgcacgagca gggtgggcac gcggatgctc cgctccagct cgcggaagcg
     2881 cgacttgcgc agcaacaggc tcacgagcga gcgcgccgcc tggaggaagg cctcatggga
     2941 ccagggcatg cgcgcgtggc gctcgcgggc gaactccaga tgcgcgcgaa ccagctcctc
     3001 ggggaagcgg ccgatgtcac ggcagcacag cgcgagctgc tcgcgggcca gcgcctccgg
     3061 agtcatgcgc gccgagcgcc gccgcacgaa gaactcgccc acgccaggaa tcgagtagag
     3121 gaggaacagg gagaggacgt tgcgctccat ccgcgagtcc tccgcccggg gttgcgcggg
     3181 agccaccagc acgaggccgg agacgcgccc gggattgcgg gccgtctgca gcacggagat
     3241 ggcgccaccc atggagttgc ccaccaggat gacgggcgcg gacggagaca ccttctggat
     3301 gaagcggtcc aacaacacct gattggccgg gagcgccgcc gagcggcccg ccaggggcgt
     3361 caaaccaaag cccgccagat ccacggccac cacccgcgcg tgccgtgcca gtcgcggacc
     3421 cacgcccatc cagttgtggt gcgagcctcc caatccatgc acgagcacca gggtcggccc
     3481 ggagccgccg aagtccatga agtgcacggg gccgtcgata tcgagcgtgc gcgtcaacat
     3541 gcctcctgcc taccacgttc cctcgcgatt gctccggctc cccaccggct ggtaaacccg
     3601 agaccacatg gccgagttcc cagagaccac ctccgccgcg ttgaagctcc tggaacgcgc
     3661 ccggcaccac gtgcgcaccc gttcacgaaa cgaggcgtac taccaggcag gggaccgctt
     3721 ctccgagctc ttcctcggca ggaccttcca ggtggagccc gactactacc gggccgtggg
     3781 cacggactac tccgccatcg actggctcta cgaggagctc gcacagggtg cggcactgac
     3841 ccggcagacc ctggacgcgg tgacggagca gttgcaggag atgacccgcc ccgagcccgc
     3901 ccgcgccgcg ctcggaccgc tccaggccgc gctccactct ccctcgtgcg ccctgctcga
     3961 cgtgtgccgg gccctgctgg gcgccatcac ggtcctgggc caggacaccc taggcgcccg
     4021 gggtgttccc gcggcgctcg tccaggactg gttggagttg tggtcggacc gcctctggcg
     4081 gcagaacagc cagcaggcgc ggctcgccct cctcatccag gtgatgcgcg ccgccccgga
     4141 ggacagaccc gggcggctgg ccgcgctcgg ggacgagcag gacgcgttga gcgcgcaggg
     4201 caccgacttc gagcagggcg tgcacgagta cctggagcgc tacgccgaga cgggtgcgtc
     4261 ctccgtcgcc ctggcgggcg gcctgccctt cgcccgcgcg ctcaccccga gggatctgga
     4321 gaagctgctc ggggtgctgc gcgaggactc ggacttcctc gggggcgtgg cgcgcctgct
     4381 gcgcttcgcc caggacgtcc ggttcgatcc ctccgaaccc ctcaactcgg gggtgatggg
     4441 ttacgcggcc gagcaccgcc aacgcctcac cgacatcgac gccacgcgcc tgccccggga
     4501 ggagctcgac acccggttga ggcaggtctg gacggacaac tccgcccgga tccgccggga
     4561 actcgacgcg gtggtggcct cgctcggaga cgagcccctg cgccccctgc tccagggttt
     4621 cgtccagagc gtctgggccg tggcctcgcg gctgaccgac gccggacacg acccacgtcc
     4681 gggcccctga cctcgcaccc ggcgactggc gccgccgcat cctcggagct ggatgcggcc
     4741 tcccgcgcgc tatgcccgca gcagctcgtc caggcgggcc tggaccgtgg tgtcgacggg
     4801 cgagccttca ctgagcgcgc tcaccaccgc gccatccagg acggcgagca ccagttgggg
     4861 actggggagg cgtgtaccgc cgggcagggc ggccgcgatg agctccgcca gcgcctcgtc
     4921 gaggtccgcg cgtccccggg cgagcaccgc cgagaaggcc gcccggcgcc cgcacgccac
     4981 caacagctcg tagtgggcct ggatggcgcc aggacctccg gacgggagca tcgcctgggt
     5041 cacccaccgg gccaggtccg ccttctccgg gtgcgcccga gcgagccgcg tggtgcgacg
     5101 gacctgctcc acccactggc gcagcatctc cgcgagggtc tcggcgatca gctcctccag
     5161 ggaggagaag taataggtga cggcggcgag gggcacctcg gccgcgtccg cgacggagcg
     5221 ggcactcacg gcctggaggc cccccgtccg cagcacgtgc gtgacgccct cgatgagccg
     5281 cgccctccgc tgccgccccc gctcctggct cgtcccccgt gggcccgggg gtgacatcag
     5341 tggccgcccc cggacagggc gagtccgatg acaccgatga cgatgaaccc gatggaggca
     5401 agcttcaccc cggacaccga ctcgccgaac aggaggatgc cgagcacggc ggtcagcgcc
     5461 gcaccgatgc ccgtccacac ggcgtaggag ggccccgccg gcagggactt catcgcccag
     5521 gccagacccc cgaagctcat cgccgccaac accaggaaca ccacgctggg caccggctgg
     5581 gtgaagccct cggacttctt gagcgcgagc gcccacccac tctccagcac ccccgagacc
     5641 atcagaacga accaggccat gacatccctc gaagtggtac ggatgtacca ttttcggaga
     5701 accctaatga accgggctct cctgggccag gaaatcgtgt gccggggatg acagcggtgg
     5761 atcagcgctc gccttcgtcg acgatcgcct ggatcgcggc ctccaaccag cgacgggtgg
     5821 aggagtggcg cacctcggcg agctgtggga ggggcaacag ccgccagctc atgagaaagc
     5881 cgttccagag gatgttgagc cgcgccgcgc gcccctcggc atccggggga cccagccagc
     5941 gagccagggg ctcgatcgcc ttcttgtgga gcagctcgac actcgtcgcg tgcgcctcgg
     6001 gatcggccgc cgagaggatc agcatcatca gtgggcccgg ggaatcctgc acgccgagga
     6061 agatggacac cacgttctcg ccgaagcggc gcctgtctcc ctgaagcatc ggggtgatgt
     6121 cgagcacctg ctccaacgtc tcccggtaca gcccctgctt cgagccgaag tagcgattga
     6181 cgagcgagga gttcaccccg gccagctccg ccacatcccg cactccagtg ttggcgaagc
     6241 cccgcgtgga gaacagcgtc tgcgcggcgg agagcagggc ggcacgcgtg cgatcggcgt
     6301 ctcgctgccg cgtcgacgtc ttggggtcgc tcggtcggga tgtgtacacg gctgtttact
     6361 tacgataggg attgcgttat gtccagcgat gtaaacggct gattacatcg agagcggctg
     6421 ccgagccgaa aggacgtgtg cggatgactg cgacgaagaa gggtgaggtc tctttctctc
     6481 cggaggcact gagggagaaa taccggctcg agcgcgagaa gcggctgcgc cccgacggca
     6541 acacccagta catccccctc aaaggcgtct tcgcggactt cgacaaggat ccctacgtcg
     6601 agcccggctt cacccgtccg gcgctgaccg agaagatcga cgtcttgatt gtcgggggtg
     6661 gcttcggcgg catgctggcg ggagcgcggc tgcgccaggc gggggtcgac tccttccgca
     6721 tcgtggagaa gggaggcgac ttcggcggca cctggtactg gaaccgctat ccgggcgccg
     6781 cctgcgacgt ggagtcctat atctacctgc cgctgctcga agagaccggc tacatgccca
     6841 aggagaagta cgccaaggcg ccggagatct tcgcccactg ccagcgcatt ggccggcact
     6901 tcgatctcta caaggcggcg ctgttccaga ccctggtcca gacgatggac tgggacgagg
     6961 acacccggcg ctggaacatc acgacggatc ggggcgacaa gctcgcggcg cggttcgtga
     7021 tcatcgctgg cggcatcctc cacaaggcga agctgcccgg catcccgggc atcgagtcct
     7081 tcaagggcca ctgcttccac accagccgct gggactatgc ctataccggc ggcagcccca
     7141 cgagcagcat gacccggctg gcggacaagc gcgtgggcat catcggcacg ggcgcgacct
     7201 cggtccaggc catcccccag ctcggtgcgt cggccaaaca gttgtacgtc ttccagcgca
     7261 cgccctcggg cgtcggcgtg cgaggcaacc agccgacgga cccggaatgg gtgaagacgc
     7321 tcgagcccgg ctggcagcag gagcgcatcc gcaacttcac cgcgatcgtc tccggtcgta
     7381 agcaggacgt cgacctggtg cgggatggct ggacgtacat cttccaggac accgccaccc
     7441 agcaggccca gacgccccag gaggccgccg agttccgcca gctggcggac ttccgcaaga
     7501 tggaggagat ccgcgcgcgg gtggacgcca tcgtcaagga gccggcgacg gccgaggcgc
     7561 tcaagcccta ctacaaccag ctgtgcaagc ggccctgctt ccacgacgaa tacctggaca
     7621 cgttcaatcg gcccaacgtc cagctcgtcg acaccgaggg caagggcgtg gagcggatca
     7681 cccccaccgg cgtggtggtg aagggcaagg agtacgaggt cgactgcctc atctacgcct
     7741 cgggcttcga ggtctcgctg gattacaccg ggacgctggg cttcgacatc cgcgggcgcg
     7801 gcggcaggtc cctgcgagac agctgggccg acggtccggc gacgctgcat ggcatgcaca
     7861 gccgcggcta tccgaacctg atgatgttca gcgtcatcca gagcggtcat gcgatcaact
     7921 tcgtgcacat cctcgacgag cagtcgcaac acgccgccta catcatcgag cggtgcgtca
     7981 agcggggcat cgaggtgatc gagccctcgg agcaggccca gcagcagtgg tgggagttga
     8041 tcctcggccg tctcatgacg acgagccccg tcttcggggg ccccgagtgc acgcccggct
     8101 actacaacaa cgagggggtc aagatgggcc cgaacgcgat gcgctacgcc tccttcgggg
     8161 gtgacacgct ggcgttcatc gacgtgctgc gcacgtggcg ccagggcgag caactcgcgg
     8221 gcctggagct cacgcgcggc gaggtgtctt ccacgccatg agagcctcca tgtcccgatt
     8281 cctctccaag tccctggccg cctgtctgtt gatggcgggt ggtcaggtcc tggccgcccc
     8341 tcccaagacc taccgccagg aagtggtggt ggccggctcc cacttccagg gcgtccacgg
     8401 gctcgtcgtg gatggcaagg ggcacctgct ggccagcaac ctgctcggcc ggacggtcca
     8461 ctccgtcgac ctgggcacgg gcgcggtgag caccctggtg gggccgccgc tgggcggcgc
     8521 ggatgacgtg accctgggtc ccgacggctc ggtctactgg acgggcttct tcaccggcga
     8581 gttgatgcgg cgcaccccgg atggaaagac gcgcgtcatc gccaggaatc tgccgggcct
     8641 caactcgctg gccttccgcc gcgatggccg gttctacgtc acccagctcg gccggggcga
     8701 tgatgcgctg tgggaggtgg acccgagcgg gaagaagccg cctcggctgg ccatcgccag
     8761 gcccggcttc ctcaacggct tcgagttcgg cccggacgac aagctctacg gcccgatcct
     8821 gctcaagggg cagattgccc gggtggacgt ggacacgggc agcatcgagg ccgtggcgga
     8881 gggcttcgcg atgccggtcg ccgtcaattt cgacgcgcgc cgcgagaacc tctacgtggt
     8941 cgactcggcg cggggcgagc tggtgcgcgt ccggctgccc acgggcgcca aggaggtcgt
     9001 cgcgaagctg cccaccgggc tcgacaacct ggccgtgggc ccggatgacc tcgtgtacgt
     9061 gtccaacatg gtcgacaacg acatccgcgt ggtcaatccc gccgatggtt ccgtccggct
     9121 cctggtcgag tcgcgcctgg ccgtgccctc cggcctcgcc gtcgccccgg atgatccgga
     9181 ggagcagctg tacgtggcgg acgtgtatgc cctgcgccgg gtgggcgggc gcgatgggaa
     9241 gatcacccag acgacccgcg tcctctcctc cccgctcaac ttccccatga acgtgagcct
     9301 gagcgcgaag catgtggtgc tgagcacggc ctacctgggg gaccggagca gcgtgcaggt
     9361 gctggatcgg accacgggag acatcctgcg gacgattccc aacgcgaatg gcgtccaggc
     9421 cgcgctcgag ctcgccgatg gcacgctgct cgtcgccgag gccaccacgg gccggctcgt
     9481 ccgggtggac accgccgagc ccgcggggac cacggtgctc gccgagggcc tggagggacc
     9541 ggtgggtctc gcggccgaca cggaggcgga ggagccgggg gtgtacgtca ccgaggtgcg
     9601 ctcggggaag gtgacccggg tgcgcctgtc ggatggcgcc aggcgcacgg tggccaaggg
     9661 cctcaaggcc cccgagggca tcgcccggca tccggacggc gggctgatcg tcgccgaggt
     9721 gggccgcaag cggttggtgc gcatcgagcc ggccacgggc cgactgagcg tcatcgcgag
     9781 cggcctgcgc atcggtgtgc ccgagagcgc gggcctgccg ccgggctacc tccccacggg
     9841 ggtggcggta ggcggctcgg gaaccatcta cctgacgtcc gacatcgaga gcgccctcta
     9901 ccgcttcgtc ccggtgccct gagagccgcg cttcgcccag gcacgcggtt gaaacgggtc
     9961 cgggcggacg actccgcccg gacccatcgc tcgcgcccgg ctactcgtac tgacgccgct
    10021 gcatcatcag cagggcgcac agctcgaagg ccgtgtcgat gcgctccatg cggtagagct
    10081 ccttggagat ccagcacttc accttgccct cggccggggc gccgggggtg tagttctgca
    10141 gcatccaccg cgaggcccga tccaacgccg gggagatgcc gtggtggtgc aggccatggc
    10201 gctccaggaa accgagcatc agcacggcgt aggaggtctc cgtcatgttc gagcggccat
    10261 cggagctcca gcccccgtcc gggagctgcg cggagagcac cgactccagc gcgcggcgca
    10321 ccgcgtccgt gtgcggcgag ccgacgaggc cgaccaccga gtggaacgtg gtgtacagcc
    10381 acgagcggct ccacttgtcg aaggaccagc ggccactggg ctcctggcgc tcgagcaggt
    10441 agcgctggaa gggggccagc tcgtcgctgt cctggcccag caacatcagg gcatggaggc
    10501 aacgggccgt cagcgtcggc gaggactgca tctctcccgg gtaggcgatg aagtggtcgt
    10561 cccgcttgaa gcggtagagc accgccggat ccaccggaag acccatggcg tgcatgacgg
    10621 ccaccaccgc gctcgtgtcg tcaccgtcct ggaggaagta gtcgctcatg ccgatgccgt
    10681 tcggcccgag cgcccgggtc agatccccca gcacggagtt cacgtagggc gccagacgcg
    10741 gctcctgcag caccccgccc atgagcaggg catagaggac gaaggactgc tcgaagtagt
    10801 tgtgcggccc gcccaccggc acgagtccgg gagtggacga cgcggtcgac agcccgctct
    10861 cgcgcaggta ctcccgggcg cgatcgacga acggcgtcag ctccggccgg cccgaggcgg
    10921 ccttcaccca tgccgccgtc gcggacgggc tgtgccccac gctccccgcc ccatcgatca
    10981 ggttcgccgt gggctcctgg ccccaggtct cccagacgtg cagccacggc acgccgggcg
    11041 tcacgggcag cttcgcgatg atcttccgct tgcgctcccc cagcgccatc agctgcgcgt
    11101 agggcgtgcg cggcagttgc gcctcgccca gcccgagctg attcaacaac gcgggcacga
    11161 ggatctccgc ggccaccggc agctcctccg gatgcagcgt ggcccagtgc ggcgcctggg
    11221 cgcgcaggaa gcgcaccccc gcctcacagg cctcgtgcgt gcgcgggtgc tggggaaagc
    11281 ggcgcaacgc gaggatggcg gacatcgtgg ggatgtcccg atgcatcggc ttgatcggct
    11341 ccccccagcc cccatccgcc cgctgttgtg acaacaacca gtccaccacg ggagaagagg
    11401 cgctctccgc gggtgaaagg attctcaaga cctgggccga atcgtagatg gaggggctca
    11461 tcaaccctcc gccatggcct gtcttggaaa gcagggattg aagctccttg aacaggagtt
    11521 cctgaattcc cccctcgacc acgcggatac tctgcgaggg gaccaactcc atcgcgacat
    11581 cccggattct tctcatagcg ccgtcaactc cttgagggag aagggacctg gcagacattt
    11641 cctcgaacct ggatgaggag cacgccggtg gaacccggaa cgagcgtgtc acttatcaat
    11701 catttctcca aaaaaagcat caccccgcac cagtcacgcc accaaggtgc gcgcgtatcc
    11761 acactcgccg caacaggctc tggactccca cgtcgggtcc tcgacggatt ccatgtaaaa
    11821 cctgtatttc attccaaaaa caagacggaa ttggtcccaa tgaattggat ggaatcggtc
    11881 caatcgagga gaaccccacc agacggggag caccgaggga cgcaccacgg ggccggagcc
    11941 accgcgctcg cgccggcaac cgccccggaa gcacgccccc cccaccggat tgcgacagtc
    12001 tggaaatcct cacatgtcac gcaatcgtga tttcagctcc ccggcgcgga cccccgtccc
    12061 cgctcgtgcg gctgacacca cggcgtgtgt cttcaggaat tatccatgtg tcttgtattt
    12121 ctcgctccgc cccgccatcc gcgcggcgga gccctccggc cccagagagc cccggcaacc
    12181 aatgacagtt tgaaattcaa gtaggctcgc gccagcggct ccgccccacc cgcgaagaag
    12241 tgatgcgggt tgccgtcgag tccctcccgg gagaactcgg aacccggctc tggacgtcca
    12301 atcatcgata tatcaacatg catcgatgag aaatcgcccc gaggggccac cctcccggac
    12361 accgcaccgc gttgccatgt ggggaacggt ggtctagaga caaggaccat ggccgctcac
    12421 actcttcaac aaaccctcca tggcaaacga ttcgggctcg ttctttccgc cggctacttt
    12481 ggcttcttcg gacacgcggg cttcctcaag gggctggcgg ccacggggct gaggccggcg
    12541 gcgtacgcgg gaacgagctc gggggggctg gtggcggcgt acgcggcggc ggggctgagc
    12601 gaggacgcca tcgaggagct ggtgctgcag cagacgcgcg agtcgttctg ggatccggat
    12661 ccgattggcg cggtgttcaa cgccctgccg cgcgagggcc atggggccac gggcctgctc
    12721 aagggagaac gcttccgcaa gctgctggag cgcacgctgc cggtgcgcac cttcgaggag
    12781 ctgccgcatc cgctgctgct cacgagcgcc aacctcacgc agggcacgca cgaggtgttc
    12841 acctcggggg agctggtgcc ccgggtgcac gcgacgtgcg cctacccggg cctgttccgc
    12901 gcggtgcggg tggggcgaga cctgtactgg gacgggggcc tggtggacaa ggcacccgcg
    12961 ctgtccctgc gcgagagcgc cttcggcaag gaactggacg ccatcctcgt gcactacctg
    13021 ccgagccgca cgcgcaagat gctgggcggg cccatggcgt acgcgcaggg catcgcggcg
    13081 ggctcggcgg cgctgcgacg cgaccacttc cagctgcagc tcgccctgct caaggagcgg
    13141 ggctttcccg tctacgtgat ggtgtccaac ctgccgcccg tgtcccccac gcagatggag
    13201 cgcggcttcg atgcgctcca ccaggcgagg ctgagcgccg agcgagcctt cgcccggcca
    13261 cccgttccct tcgaagaggc ctgagacgag gcgtgaggca accgcgctca gcgcgcgtag
    13321 cgccggtggt ccaccatgag acaacggtcc tggaccaccc ggatgcccgc ctcggccagt
    13381 cgccgcgccg ccgcgtcgtt gcggatgccc gactggaacc acaccgcctt gggcttcttg
    13441 gcgaggatgt cgtccacgtg ctggtcgatg tcctgtggtc ggcggaacac gtccaccaga
    13501 tcgatgtcgc ccggaatgtc cacgagcctg cggaacaccg gccgctcgag gatgtgcgtc
    13561 acctccgggt agtagacggg cacgggcacc acgtccacgc ccgcctgggc gaggtactcg
    13621 ggcacataga aggcgggctg ccccgagtgc tgctccgtct tgatgcccag caccgccacg
    13681 cgcctggcgc cccgcaccag cgcgcgaatg ccctcttcgt cctcgatgag attctgttcg
    13741 tagctcaccg ctgctcctcc tcgagcgccc gcaccgactc cagcgtcgac tgcgtcgccc
    13801 atgtccaggt ctctccgtcc aacgacgccc tgagggtgaa cccgcgccgc accgggagga
    13861 agcgtccctt gccgagcaac tgttctccgt cgcactccac gccgggtgtc agcggggggt
    13921 cgcccgcgag gcgcagcgtg tcgcgcacgg cctggggcga cgcttctccc ggctgggcga
    13981 ggcagcgcaa cgagaacacc agggcctcgc cctgttcggt gagccgcgtg ccggtgaggg
    14041 tgcgctccag caggtacgtc acctcgcgtc cgcccacggg cagcgtgccc accacgtagc
    14101 cgcgctgccc cgggacccag gcccgtccgt agatgccgcc gtacttcacc tcccactccc
    14161 cgcgcgtgcg cgcctcgagc gcatccggag cgaagaagcg ctcgagtggc gtgacatcca
    14221 gccccttggg ggccacctcg cggatggcgg ccagcacggc ctcgggctcc acgagccgca
    14281 cataggtgcc atccgccgcg agccgcagac gcagcacggc gcgctggagc acggtgtcca
    14341 ccaacgattc caccggctgg ccctcctgga ggtagcgcga gcgtgtcacg cgctgggtga
    14401 ggacccagga atcctgctcg gcggagaagc tcgagacggt ggtcatctcc gcttcccgcg
    14461 cgtccggagc gcttccgtgc cgcagggacg tgcgcaccgt ctccgtgagg agcgagtcgt
    14521 cggggggcag gaacaggggc cgcaggggag gtgccgcggc ggggggagga ttcaacgagg
    14581 ggatgtcgcg gtggcacgcg gtgaccgggg ccgcgaggag gagcaggaag aaggaggaaa
    14641 aggtccgcat gatgttccgc gcaagctggc agaaagcccc gccgcccgcg agcgcatcgg
    14701 cacctcccgc ggggccttgc tcagcggtcc atctggcaaa cacccgacgt cgtacccggc
    14761 tcgacgtgac agctttcacg cggagcgcag acgcgggcct cgttctgctt ggagcagagc
    14821 tgacgacaac gtttggcgta gcagaccatg ccgctcgggc aggacggacc gtcctcgaca
    14881 cagggaagaa cgcactccat ccaggcctcg tcatggcgag gacgcgcccc caggaagaca
    14941 tcacagacct gaggctccgg acagagttcg tcgtgctgac agtcccggcc atgcacctgc
    15001 acgcagagcg agcctccctt gcgcaactga acgcaccgtt ggccctcggg acatgacatc
    15061 ccgtcacaac tgggcaggca gaccggaccc tcggcgtcca cgtcgaggca ggcgaagccc
    15121 ggggaacagc cttggggatc ttgaggccgg cagcggcggc cgcacgagaa cgccgcgcag
    15181 acgaggccag gagcgcaggc ggaatcctgg tcgaagggaa ccttcagaca ccattcccct
    15241 tccttctgcg tccccattgc accacagaca cgaaccacgc gctcgcccac ctgcaccgca
    15301 cggcaggcaa acccctcctg gcagtccaga tccgtcatac acctgctcgc ggcacagacc
    15361 ggctgaatca tcagaagtcc ccgcaggcaa acgagcggag catcgcagtc cgcatcaccc
    15421 cggcaggcac gacccgctgt gggtaactgc ttgagttgtt cagctgaaag ccggggaaca
    15481 accttccgcg attcctggag ggaagtagac tggagtccat ggacgggcaa cagacccaga
    15541 gaccagagca ggggaagagg gaacagcaga cccaacacca gagcagcagc cgcgcgccag
    15601 ctcatggacg ggcgttcctt ctcatccgcc tctggcaatc cgccatacat tcgtcggact
    15661 tattgccgca taggtcctga atctcatctt cggggcactg ctcgtgactc gcgttttcaa
    15721 tcaagtcctt gagcacggcc tggtcgatgg tgccctcgat gccataggca tgagggcagc
    15781 ccgacgctac caccaggatg agtccacccc cgaccacgga cgcacgtgcc ctcagcattc
    15841 tctcccccca cccccgcgca gccccggagg tctggcgtca gcgccagccc tccaagcaaa
    15901 agccggatcg acagggcgag tcaacatcct gagcacccgg gggctcccct ccccgtctca
    15961 gtgcacggac caccagttgt aattggccgt gccgttgggt ggctgctgtc cgcccgtcag
    16021 gatcttctca taggcgtagg tgttcttgat cgcctggtag ttgttctcga cgttccaggc
    16081 attcgccgtt ccggaaccgc tgacatcccg aatcaccgtg tccccccaga tggagtagat
    16141 gacccagggg cgggcgtcga tctccgagac gttcttgtcc cagcgcaccg gcatcttgtc
    16201 gttctccgcc agcatgcgcg gcttgttgta gccggcgaga tccgtgtaat accgccccgg
    16261 caggtaggga ttgccgctgt agatgtcgac cgcgacgatg tccgcgccct cggtggggta
    16321 gtagttccag ggatcgcccc cgtacgtccc atcccaggca tagggggacc agacccagat
    16381 gaggttgttg aacccccgcg tcttcgtcat gtagttgaag atgatgctcc acaactgctt
    16441 gtagagcgcg ggatcgcggt tggcccacca gaagcggccc gagcgcttgt tcatctcatg
    16501 gtacggccgg aagagcaccg ggacgcccgc gtccttcagc ggctgcaagc gattggcggc
    16561 ccaggacaga tccctcagca gcgtctggta ttcggccgtg ttgttctgcc agtccacgac
    16621 ccgcttgaac cacgcgtcat ccaggttcac ccgctggccg gaggcattgg tggcggtctc
    16681 gacgagggtg ttctcgaagc tcttcaccgg actgcccgga tagggctgat gaaagcccag
    16741 tcccacgagg ccatcgccat aggtccaacg gtccttgagg aagcccaccc cgttgaaggt
    16801 ggcccgccag gccgtggcgt cctcgttgaa cgaggactgg taccagcccg gccccaggtc
    16861 gaactcgacg aacgcgggcc gcttgccgcc agagagctgg gtgaccttgt cgtagtacgc
    16921 ccccgcgtag ctgccttcct ggtggatctc cttctgcgcc tcgcagtgct ggccgatgat
    16981 cgtgcggcgg ttgcccgcgc gcgccccgtt ctccaggtcc acgagcagcc cgtagacctt
    17041 ctgcgccgtc ggcgagggag aaggcgtcac cagcgtcctg ctcacctggg ccccggccgc
    17101 accgggacac agcaccgcgc acgccactac cagcgccagc ccgctgaacc tcccggaacc
    17161 ggaggtcgat acctcatccc ctcgcttccg acttcgccac gttcccgtca ttcgcctgtc
    17221 tcccgagcgt tcgccccccg cgacgcgcga gagggagcac cttcctagat agacgggaat
    17281 tcaagatttt tcctgttgtt tcgcttcgcc ggcccggcgg ggggacgccc caacgaaacg
    17341 cccgtgaacg tgggaggcaa gagcccccgc gcccacgggc aggtggtgtc ccgaaaggag
    17401 ccgccgacta cgggtgacgg gaggtgtcgt ccgaggcgcc ctccaccagg tctctcccga
    17461 tgttgcgccg gtcgcgcacc acgccgtcgt cgtcgcgcag gcccccattg gcgaagcgcc
    17521 gcgccgcctc cgccaggtcg cgcatcactt cctcccgaga caggtactcc tcgcggggca
    17581 gcgccttgaa gacgttgatg atgtccacgc ccgcaccgtt gtcctccgcc gcttccacga
    17641 gatgctcgcg tctggcgggg tagtccacgg aatccaggtg gggcgtgatg gagcgcgccg
    17701 ggttctcccc ctgtccgaat gccatcgtgt cctctgtctt tccgcccgga tgtcttcttg
    17761 gccggggctt ggtctcaacc tggggatgga tcctccgcgg ggccacttcg cccgggtccc
    17821 ccgcccgttg tcccccgggc agccggccag ccatcctccg gcatggcgac gcccttgcgt
    17881 cggccccggg attccgttgt gttccgtggc cgacggcgcc ccatcgcccc aaaggagaca
    17941 cgcaccatga cggaagagag cggacgggag atgctggaca tcgccagcaa gctcttcgag
    18001 cagatgttga cccagcagcg cgccaaggtg ctgcgcctgg cccgcgaggt cgtccccaac
    18061 atcacccccg aggagctgcg caacccccat gacttcccga aactcaagga acacccgacg
    18121 ttcgagttcg aggatggact gctctcgggc ctcatctcgg cgcagatggc gctctacgcc
    18181 gaaatcaagg gccggttgtt gccccccgaa cctccgggtc agtgactgcc tgcctgcctt
    18241 tgccgtctgc ccgctcgtgg gttagtgctt agcccgtgag catcacctcg acctcgacct
    18301 tgagctcgcc cctggcccgc gaacgcctcg tgtccgccct cgccgccgat ccgccgcgac
    18361 tggacctcgc cgcgctggcc atcgccacgc tcaatcagcc ccacctggac gccgcggcgt
    18421 gcctgcacac cctggacgcg ctggccgccc gcgtgcaact ggagatggag cggcacgcgg
    18481 gccacggcga ggtgctcgcc ggcctcaccg cgctgcggca cgtgctggcg gacatcgagg
    18541 gctttcgcgg caacgaggac gactaccact cgccggaaaa cagcttcctg gacctggtgc
    18601 tcgagcgcaa ggtgggcctg cccatctcgc tctcggtgct ctacctggag gtggcgcggc
    18661 gcgcgggcat cccgctctac ggggtgtcct ttcccggcca cttcctggtg gcgtgcagcg
    18721 cgggggacca caagctcgtg gtggacccct tccacgaggg ggagatcctc accgaggagg
    18781 gttgtaagca gttgctcgag cgcgtggcgc cccagttgcg cttcaacccc tccatgctgt
    18841 cgccagcgcc cgtggagctc atcgcctacc ggatgctgtc caacctgcgg cgcgtgtacc
    18901 tggagcgctc ggactatgag cgggggctcg ccgtggtgga tctgctgttg atgctcgccc
    18961 ccaaccaccc gggcgagctg cgcacgcgcg cggcgctcct ggccaacctg ggggcctacc
    19021 gcgcggcgct caaggacgtg gagcgctgtc tggagctgtc cccggacgcg ccggaccggg
    19081 agcggctgga gatgacggtc cgggagttgc gcgagcgcgc cgagctgctg aactagcccc
    19141 atgcgcccac ttccaccgtg gccccgcctt cgccggggcc tggagcacga ctacaccatc
    19201 ctcaccgtcc gccaggacat cgtcgcggac ccccgcacca gccaggagca cccccgggtg
    19261 cgcatcgact gcggcgactg ggtgaacgtc gtcgcggtga cgcgcgagga ccagctcgtg
    19321 ctcatccgcc agtaccgctt cggcatctcc gcggtgacgc tggaggttcc cggcggcatc
    19381 gtggagcccg gggaggaccc ggccctggcc gccgcgcgcg agctggagga ggagaccggc
    19441 tacgtggcgg gccgggtggt cgcactcggg tcggtccatc ccaacccggc gctccagggc
    19501 aaccggtgcc acagctacct ggcgctcgac tgcgtgaagg cccacgaggg caacccggat
    19561 gccggcgagg acatccgcgt ggagctccac ccccgcgagg ccgttccccg gctcatcctc
    19621 gaggggagca tcacccactc gctggtggtg gtggccttct acctggagca cctgcgcgcc
    19681 gcggcgcccc gttgactccc ccctgggggg cgagtggagg cgctcagcag cccaccagac
    19741 gcagccacag ggagatcatc gcccagctgc gcagccggtt gcggtggccg ttgacggcgt
    19801 ggccgacgtc gtcgaccttg tccacgaaca cgtacggcga gcggggatag gcccgggcct
    19861 cctgagcggc ataggccgcg ggcgccaccg cgtcgaactc gcccagctgc accatgatcg
    19921 gcacggtgat cttctcggcc gggatgggct ccgggttctt cagcagggtg aagaggtcca
    19981 cgagctgtcc gcgcggcacg aagtccgcct cggtgttgtc gtaggcgatg accgccgggt
    20041 ccacgtgccc gcgattcgga tcgtagaaga gcgcggtgcg cagctccggg ggcacctgca
    20101 cgtaggggcc ctgctccagc agcgggccga agacctcgtc ccccacgggc agcgggtggt
    20161 aggtgttgag ccagccggtg agcaccaccg catcggcgtc ccggtagtac gcctgcgcgt
    20221 aggtgatggt gagcgcgccg ttggagtgcc ccacgtagag gatcttctcg aaggtgttgc
    20281 gcgccgcggt cgccttgagc cgctgcacca cctggtgcag ggagctggcc gactccgaca
    20341 gatcgaggaa gtccccgttc ggcttgtcac tctccccggt gcccagcaga tccaacgcga
    20401 gcaccgcgta ctgctggcgc gccatgtagc gcgcgtacga gtagtcctgg cggttgatct
    20461 ccggcagatc ccagtagttg tggttgtagg tgatgccgtg cacgaggatc tgcaccggct
    20521 tgttcttcaa gctcccctgg taatacaggt agcccacgag gttgtagacg cgaccgttgg
    20581 acaagcgcac ggggaaggtg cgccgctcca ccttgatgcc cccccaggct ccggtctcgg
    20641 catcggcatc caccgccgca gccctcgccg gaaccaggca cagccccgcc accaccaggg
    20701 ccatccacat gctcatccac cggaccgtgc ttttcattgg aaccatcctc atacgactgt
    20761 tctagaaaca tcaatgtaca ctaaaaacaa gaaggatccg atagccttgg attgccgagt
    20821 tgtacatttt tcacacgatt ctcctgcatt tccgttaatt ccaataaatt atatttttat
    20881 tgaaataggg cgactcgtga cagcaggagg cgtgccccgg ccccgccgga atctgacacc
    20941 atggccggcc acggagggac agacggcgtg aggcgacaag aggtggagga gcggctgggg
    21001 agactggagt tgccgttcaa cgcctatggg gtggatccct acggcgtgtc ccggtggcac
    21061 ctgggagtgg tcttcgaggt gcaggcgttc ttctaccgga actacttccg ggtgaagtgc
    21121 cagggaatcg agcacgtgcc cgcccggggc cgggccatgc tggtgggcaa ccactcgggg
    21181 ggcgtggcgg tggacggggc catggtcgtc gcctcgtgct tcctggaggc caatcccccg
    21241 cgcctggccc aggccatggc ggagaagttc atcggcgcca tgcccctggc gtcggtgtgg
    21301 gccagccgct gcggtcactt caccggcctg ccggagaacg cgcagcgcct gttggaggac
    21361 gaacggctgc tgctcgtgtt ccccgagggg gcgcggggca ccgcgaagct ctacccccag
    21421 cgctatgatc tggtggactt cggcacgggc ttcatgcgcc tggcgctcaa gacccgcacc
    21481 cccatcatcc ccttcggctt cctgggaggg ggctcggcca tccccacggt ggccaacctc
    21541 tacgggctgg gccgggcgct cggcatgccc tacgtgcccg tcacccccta cctgct
//
