LOCUS       NZ_CP022098            23345 bp    DNA     circular CON 17-FEB-2024
DEFINITION  Cystobacter fuscus strain DSM 52655 chromosome, complete genome.
ACCESSION   NZ_CP022098
VERSION     NZ_CP022098.1
KEYWORDS    RefSeq.
SOURCE      Cystobacter fuscus
  ORGANISM  Cystobacter fuscus
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Cystobacter.
REFERENCE   1  (bases 1 to 12349744)
  AUTHORS   Rupp,O., Goesmann,A. and Sogaard-Andersen,L.
  TITLE     Sequencing and comparative analysis of myxobacterial genomes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12349744)
  AUTHORS   Bruckskotten,M., Treuner-Lange,A., Rupp,O., Goesmann,A. and
            Sogaard-Andersen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2017) Department of Ecophysiology, Max Planck
            Institute for Terrestrial Microbiology, Karl von Frisch Str. 10,
            Marburg, Hessen 35043, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 09-AUG-2016
            Assembly Method                   :: Celera Assembler v. 8.1
            Expected Final Version            :: yes
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/17/2024 10:04:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,093
            CDSs (total)                      :: 10,016
            Genes (coding)                    :: 9,906
            CDSs (with protein)               :: 9,906
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 26 of 110
            Pseudo Genes (incomplete)         :: 101 of 110
            Pseudo Genes (internal stop)      :: 1 of 110
            Pseudo Genes (multiple problems)  :: 17 of 110
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:24:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9085228
            Orig. end                         :: 9108573
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23345
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="45"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23345
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23345
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13345](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13345)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(354..2711)
                     /locus_tag="CYFUS_RS36695"
                     /old_locus_tag="CYFUS_007251"
     CDS             complement(354..2711)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03696.1"
                     /locus_tag="CYFUS_RS36695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007251"
                     /product="RHS repeat-associated core domain-containing
                     protein"
                     /protein_id="WP_095989435.1"
                     /transl_table=11
                     /translation="MLKLGEQQTRELRRLQLGELLLRNLNALGQEAERDPLTGDILARD
                     GRGHVRRLHLDPLGYVGGVTTPLNRRWHMENDSEGHLQALTLPSGMRFGMRYQGSKLVE
                     ISDDQQHVWRISYDAQGQPRKLTHPDQTATVLEHQASGLPTLLQDRLGGVTCFEYDERE
                     RLTTLTDPGGRRTRFTYGAGPNPHRVERPDGSAEHYTYDASGRLLSCSVGQMPLFTVAY
                     EGTSHREIRYADGVVLHLTQDARGRVTRAAGPEGEVEFTYDEQGKLVRERQDEQVIEYT
                     YDEAGLLTALVLPSGEQVRYGYDADLRLAEVTDWNGGLHTMEHLPNDRGHQFHAANGVT
                     TSVGLSKAGLPQWSESRHGGANGALLFRQDYTHDEQGRLLSTKDSEHAERSFHYDAEGR
                     LLATQSAGLPDEEFAYDACGNRVRANGEQASFDAADRLLYQGEQQCAYDERGNLISLHE
                     PAGQWYFEYDARNLLVRARTPAGLEVTFGYDALGRRLWKRTARREVRYLWAGEHLVREE
                     RREQGQVTIQDYLYQPGTHVPLAMRVDGQVYLFHTNLQGAPERITDWLGRVVWSAVYGA
                     FGLASVSGRVDNPLRLPGQYHDEETGLHYNRFRYYAPRLGRYTSPDPLKWLNGTHFYAY
                     AHNDPINRTDPLGLWSWGGRAVGGGRRRGGGGGGGRGRSGLASTAAGRRRGHGRGAGRQ
                     HGPERRGILPLLLPGRGRQGVADDGPLRRRIAAACRGRPPCRGRGGRGAGHRGDRGYGG
                     PRHVVGRHVDGAEKWIFCSRNGRSRRGREGLR"
     misc_feature    complement(771..773)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2721..3593)
                     /locus_tag="CYFUS_RS36700"
                     /old_locus_tag="CYFUS_007252"
     CDS             complement(2721..3593)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024894.4"
                     /locus_tag="CYFUS_RS36700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007252"
                     /product="DUF4123 domain-containing protein"
                     /protein_id="WP_095989436.1"
                     /transl_table=11
                     /translation="MSTRLIVEIRFKAPALHRAVLEPGQVLRVGRGEQAGLVVASDPHL
                     SALHFELVWNGMTCLLRDLDSATGTLLDGRRITKEAQIHHGAWVRAGTTDLSVYFEGAT
                     PPAEPLTPERVQLASRLLEVLEVESLPLLAVLDAARSERVRVLLRESVEFSKSLYEGPQ
                     AEVLAEVAPYLVSLPREGRLLHALLAEGWGKSWGIYLACAQPFAEVRRHLRKLLMVEGA
                     TGQELYFRFYDPRVLRPFLRTSSASLVREVLGPIDCFWLQGEQPEQILRIHYTPEGGRE
                     ASPRLPPRT"
     misc_feature    complement(3204..3206)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3590..3949)
                     /locus_tag="CYFUS_RS36705"
                     /old_locus_tag="CYFUS_007253"
     CDS             complement(3590..3949)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017315.4"
                     /locus_tag="CYFUS_RS36705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007253"
                     /product="PAAR domain-containing protein"
                     /protein_id="WP_095989437.1"
                     /transl_table=11
                     /translation="MPPAARITDMHTCPKVEPGPVPHVGGPTVAGEPSVLIGFQPAARV
                     GDMLVCNGPPDSISQGEPTVLIGGKPAARLGDPTSHGGVVVAGCPTVLIGAPAQAGCMS
                     SASNSGASFVTKTAS"
     gene            complement(4027..4893)
                     /locus_tag="CYFUS_RS36710"
                     /old_locus_tag="CYFUS_007254"
     CDS             complement(4027..4893)
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624815.1"
                     /locus_tag="CYFUS_RS36710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007254"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_232537013.1"
                     /transl_table=11
                     /translation="MSPGLHGVLALFVPPAMPLVGFALAALIGVSLGLLGGGGSILTVP
                     ILVYVLGFEPKESIAMGLAIVGTTSLFGAIGHWRAGNLQLRAALVFGAMAMGGTFVGAR
                     LSVFLPGTVQLVLFATVMLVAAVFMARNARRELTTPATGAEPRAASFPLIAASALGVGA
                     LTGLVGVGGGFLIVPVLVLRVGLPMKQAVGTSLLVIAFNSFVGFAGYLGHVNVAWGALT
                     LFTGLAIAGSVGGTWLSRFISQATLKRAFAGLLVVMGVLILYENRRTFPSLGRAAAMES
                     PRPARPG"
     gene            complement(4890..5231)
                     /locus_tag="CYFUS_RS36715"
     CDS             complement(4890..5231)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163: rhodanese domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624816.1"
                     /locus_tag="CYFUS_RS36715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_095989438.1"
                     /transl_table=11
                     /translation="MSSPLFLDLLPEQLDTLGPEVRRIDVREPDEFEGPLGHLSRAELV
                     PLGTLEDACATWSRAEPLLLICRSGRRSVTAAEILARRGFGRLYNLKGGMLAVREGSAA
                     PSGSGVPPT"
     gene            complement(5245..5931)
                     /locus_tag="CYFUS_RS36720"
     CDS             complement(5245..5931)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624817.1"
                     /locus_tag="CYFUS_RS36720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_095989439.1"
                     /transl_table=11
                     /translation="MIFRQLFDAESSTYTYLLGDPSSGQAALIDPVLEQVERDLTLVRE
                     LGLRLTHVLETHVHADHITSAGRLRERTGCTVVASERGASCADLHVRHGDEVCVGALVV
                     RVLGTPGHTDDGVSYRLGERVFTGDTLLIRGTGRTDFQNGDAGHLHDSITRVLFALPDD
                     TLVYPGHDYLGRTVTTIGEEKRHNPRLAGRGREEFIHLMGNLHLPMPRKLDVAVPANRS
                     CGRLDS"
     gene            complement(6032..7390)
                     /locus_tag="CYFUS_RS36725"
                     /old_locus_tag="CYFUS_007255"
     CDS             complement(6032..7390)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008134 - transcription factor binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1112: sigma-54
                     dependent trancsriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624818.1"
                     /locus_tag="CYFUS_RS36725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007255"
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="WP_095989440.1"
                     /transl_table=11
                     /translation="MSSSRPSLNTLLVRSALEALAGDVLLVDERLRVADATPQARVRLG
                     LGELFPGRPLAEVLRFREGQGSLEALLSHGRPLEVMPRGEGGAGCSIRVRAVALDEGAK
                     RLGWLVLLSPGEAGASPQGDVEETFHGLWTRDPGMKRLFRIVEKVARTESSVLVRGESG
                     TGKELVANALHAISARRKGPFRAINCAALPPSLLESELFGHVRGAFTGAVRDSPGHFRL
                     ADRGTLFLDEVGEIPLELQGKLLRVLETRTVIPVGGRASVPVNVRIVAATHRALRREVE
                     EGRFRADLMYRLRVVPLFLPSLRERRGDILPLARRFLDELERQGSRHVERISPGAQRLL
                     ERHGWPGNVRELRNVMEYAFVIGEGPLLHEADLPPEFSEPRPSAEPRVPSASLQPGRPA
                     SALVRPVDDHDPATLRAALEEAGGNHTQAARLLGISRVTLWRRLRALGDKVTR"
     gene            complement(7408..8673)
                     /locus_tag="CYFUS_RS36730"
                     /old_locus_tag="CYFUS_007256"
     CDS             complement(7408..8673)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624819.1"
                     /locus_tag="CYFUS_RS36730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007256"
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="WP_232537014.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.3e-09, bitscore:
                     36.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEHVRAGQEGARLARIPSASRHRILIIGGGTAGISVAARLARAG
                     QKDVAIIEPSAQHYYQPLWTLVGAGEARVEDTVRDEARLIPKGVKWIQDWARDVDPVAR
                     KVSTRGGLELGYDFLVVAPGIQLDWDKVRGLREALESRPNVSSNYEARYAPKTWDMLRA
                     FQGGTALFTHPSTPVKCAGAPQKIMYLAADHFRKRGLDKAAHVVFASAGKAIFGVKEYA
                     AVLEQVVERYGIDTRFQHDLVEVRGARNEAVFRHTRADGGAEQIVLAYELLHVCPPQSA
                     PDFIKASPLAWQDGPNRGWVKADKYTLRHPDYPEVFALGDASDLPTSRTGAAIRKEAPV
                     LVENLLAVMAGREPAAKYDGYASCPLTTAYGKLLLAEFGYEGKPTPTFPFIDSIKERHD
                     MWLLKKYGLPQLYWKLMLRGRA"
     misc_feature    complement(8663..8678)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.02"
                     /tool="antismash"
     CDS             complement(8687..8788)
                     /gene="allorf_09093915_09094016"
                     /locus_tag="allorf_09093915_09094016"
                     /protein_id="allorf_09093915_09094016"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGRSCVLGGEGWHECCTGSGSFHPPRMVPTAGE"
     CDS_motif       complement(8762..8788)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGRSCVLGG"
                     /locus_tag="allorf_09093915_09094016_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(8687..8761)
                     /prepeptide="core"
                     /locus_tag="allorf_09093915_09094016_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.10"
                     /molecular_weight="2500.7"
                     /monoisotopic_mass="2499.1"
                     /core_sequence="EGWHECCTGSGSFHPPRMVPTAGE"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGRSCVLGG"
                     /leader_location="[8761:8788](-)"
                     /alternative_weights="2518.7"
                     /alternative_weights="2536.8"
     CDS             8700..8876
                     /gene="allorf_09093928_09094104"
                     /locus_tag="allorf_09093928_09094104"
                     /protein_id="allorf_09093928_09094104"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGTILGGWKDPDPVQHSCHPSPPRTHERPILRLFQDVFQGVSRKP
                     FTLRTSSQALTGL"
     CDS_motif       8700..8720
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGTILGG"
                     /locus_tag="allorf_09093928_09094104_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       8721..8876
                     /prepeptide="core"
                     /locus_tag="allorf_09093928_09094104_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.20"
                     /molecular_weight="5703.4"
                     /monoisotopic_mass="5700.0"
                     /core_sequence="WKDPDPVQHSCHPSPPRTHERPILRLFQDVFQGVSRKPFTLRT
                     SSQALTGL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGTILGG"
                     /leader_location="[8699:8720](+)"
                     /alternative_weights="5721.4"
                     /alternative_weights="5739.5"
                     /alternative_weights="5757.5"
                     /alternative_weights="5775.5"
                     /alternative_weights="5793.5"
                     /alternative_weights="5811.5"
                     /alternative_weights="5829.6"
                     /alternative_weights="5847.6"
     misc_feature    complement(8801..8815)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.09"
                     /tool="antismash"
     gene            8918..9706
                     /locus_tag="CYFUS_RS36735"
                     /old_locus_tag="CYFUS_007257"
     CDS             8918..9706
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024819.4"
                     /locus_tag="CYFUS_RS36735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007257"
                     /product="aminoglycoside adenylyltransferase
                     domain-containing protein"
                     /protein_id="WP_095989441.1"
                     /transl_table=11
                     /translation="MNPPQDIPTHVAPAVARYTDAVVKRLQAVLGDALLGVYLIGSNSL
                     GGYEAGPSDIDLIAICARPVELATKEALARELDHRALPCPARGLEFVLYPKDTVSRPTP
                     SPRFELNLNTGAGMGHRFTVRPEDESPHWFVIDLDIARQHGVRLAGPPANELLAPQDKR
                     WVLDAIRTSLAWHSREEPASANNVLNACRAWRYAEEGVWSTKLAAATWARERLEEPSLI
                     DAALATRRGQPGPALTPEAVHALVQRVLRVVERAMPRDNP"
     gene            complement(9792..10004)
                     /locus_tag="CYFUS_RS36740"
                     /old_locus_tag="CYFUS_007258"
     CDS             complement(9792..10004)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011552917.1"
                     /locus_tag="CYFUS_RS36740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007258"
                     /product="mersacidin/lichenicidin family type 2
                     lantibiotic"
                     /protein_id="WP_095989442.1"
                     /transl_table=11
                     /translation="MSKSNTEHILRAWRDPEYFNSLSAEERAALPANPASAFALDDSVL
                     ESVTGGGILEPTSAYCTPCPPKYCY"
     CDS_motif       complement(9852..10004)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSKSNTEHILRAWRDPEYFNSLSAEERAALPANPASAFALDDSVLESVTGG"
                     /locus_tag="CYFUS_RS36740_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9792..9851)
                     /prepeptide="core"
                     /locus_tag="CYFUS_RS36740_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.20"
                     /molecular_weight="2052.4"
                     /monoisotopic_mass="2050.9"
                     /core_sequence="GILEPTSAYCTPCPPKYCY"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSKSNTEHILRAWRDPEYFNSLSAEERAALPANPASAFALD
                     DSVLESVTGG"
                     /leader_location="[9851:10004](-)"
     gene            complement(10001..13345)
                     /locus_tag="CYFUS_RS36745"
                     /old_locus_tag="CYFUS_007259"
     CDS             complement(10001..13345)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002636955.1"
                     /locus_tag="CYFUS_RS36745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007259"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_095992454.1"
                     /sec_met_domain="DUF4135 (E-value: 3.4e-111, bitscore:
                     371.2, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.5e-63, bitscore:
                     213.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSSDNDADAQGAKGGETPAASRWYLGTELSERILALRRHGGPVR
                     TAGERARRRAERWRAQEPFVREEWWTRRLAADGLTEEDFLSLLGLSPEALRSSMESAPA
                     WLQEIERAYVEPVSEPFSWPERAGGPERSAFLALAEPLVRSGLARLLRGLGELETSFPG
                     ALFEPETLGRELLGHLPTLLTPLLSRTLVVELHAAQLQERLTGDTPRARFQDFAHSLRR
                     REVALEILARYPVLARQLVECIAHWERAGVELLRHFREDAPELQRRFSGGVPLGRLVEA
                     EGGVSDSHRGGRGVFLLRFESGTRLVYKPRSLATEAAFQRLLSWLAQQGLEPAPRTLEV
                     LDRGDHGWVEFVTPAPCSSAEEVRRFYLRQGGFIALLYVLDATDFHHENLIASGEHPVL
                     VDLETLFHPPVRVREQRDTERHPGAPLGESVLKSGLLPQRTWGTRERPGVDISGLGSSA
                     GQLTPQAFLMPVERGTDRMRFERRQVEVPGSHNRPRLEGVDASLLDYADALSEGFSRMY
                     RLLLRRREALLAGDGPLAAFAEAPVRVVFRHTSVYGSLLLESFHPHALGDALERQCFLE
                     HLWKGAVERPFLASLIPFELEDLLRGDVPLFTTLPGTRHVWTSSGARLEDFLETPGLER
                     VRRRVALLSDEDLERQRWIIHRALDALRLGEPGGERPSYPVPEPGERAGREELLAAARR
                     IGEKLVGLSLRGPEEAHWLTLDYADAGGWQLAHAGADLYQGLGGIALFLGYLGAATGEE
                     SFTRTARMALCAQEHQIELDASQVRGLGLLNGWGGVLYGLTHLGVLWADARTLDRAEHY
                     LERLPALIERDEMLDLGVGSAGCLIALLTLAEHRPSELLWKAARACGERLLDSARRQER
                     GMGWVVPLAGQLALAGMSHGAAGISLALLRLAAATGDERFGRMAREGIEFERGLFSAAE
                     RNWPDLRAGAAELAGPHGGGMHFMTAWCHGAPGIGLARLSGLPMYDDARVREELAHAVA
                     TTLAGGFGQNHSLCHGDLGNLDFLLEAARVLGDEALEHQVYQRARTVLRVLDERGCLFG
                     LQRNIETPGLMVGLAGIGYGLARLAAPERLPSLLALAPPGHTIPKPKGWRHSEQSRIQP
                     PSKGEPP"
     misc_feature    13360..13373
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.36"
                     /tool="antismash"
     gene            13544..14758
                     /locus_tag="CYFUS_RS36750"
                     /old_locus_tag="CYFUS_007260"
     CDS             13544..14758
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624820.1"
                     /locus_tag="CYFUS_RS36750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007260"
                     /product="vWA domain-containing protein"
                     /protein_id="WP_095989443.1"
                     /transl_table=11
                     /translation="MTLKTFSRPALGAALALSMFAAPHALAGDPPPAPPAQVQPQQQTP
                     PPPAPPRQEAQPRIDLVFVLDTTGSMSGLIEGAKQKIFSIASRIAQGKPTPRVRVGLVA
                     YRDVGDEYVTRWTDLTDDLDGVFTHLRQLRADGGGDTPEHVGRGLGEAVSKLSWDPSRE
                     TMKLIFLVGDAPPAQREKQWNFQHWVKRAAEQHIVVNTVRCGSDPETQTQWKYAAKTTD
                     GLYESLEQSGGMAAVVTPYDAELARVNAELARKTMYAGKKEAREANQARAGQMAELPAE
                     AAAERIQFMKTTRGRGKGAAAAAVSSAPAPVQGAVDLTAQPEALAGVADDELPGELRAL
                     DTAGRAAKVKQLADERKDLEEKAAKLAAERDSWRAKNVADKQDAFDANVMKSVKAKAAA
                     HGLSY"
     CDS             14768..14905
                     /gene="allorf_09099996_09100133"
                     /locus_tag="allorf_09099996_09100133"
                     /protein_id="allorf_09099996_09100133"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MHEPAYSRIIMQNNALMRRFMRTKSAGSCVILPIWEFWCPRGGRS
                     "
     CDS_motif       14768..14851
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MHEPAYSRIIMQNNALMRRFMRTKSAGS"
                     /locus_tag="allorf_09099996_09100133_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       14852..14905
                     /prepeptide="core"
                     /locus_tag="allorf_09099996_09100133_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.30"
                     /molecular_weight="2001.4"
                     /monoisotopic_mass="2000.0"
                     /core_sequence="CVILPIWEFWCPRGGRS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MHEPAYSRIIMQNNALMRRFMRTKSAGS"
                     /leader_location="[14767:14851](+)"
     misc_feature    14789..14802
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.68"
                     /tool="antismash"
     gene            14902..16077
                     /locus_tag="CYFUS_RS36755"
                     /old_locus_tag="CYFUS_007261"
     CDS             14902..16077
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624821.1"
                     /locus_tag="CYFUS_RS36755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007261"
                     /product="MFS transporter"
                     /protein_id="WP_095989444.1"
                     /transl_table=11
                     /translation="MRASPLEVPARAEPTPGEARAAVSTVFFINGFVFASWVPHIPTVQ
                     NRLGLSTSLLGLALLGVAAGALVAMPVTGALVSRWGSRFVTLVSALLLCALVVLPVRAL
                     DFPSLVLALVSLGAANGSMDVAMNAHAVAVERRVGRTIMSSFHGLFSLGGLAGAGGSVL
                     LLSRGMPPETHLLGVAAFGGTAVLACARFLLPASADGTGAAHAFALPRGPLLVFGAAAF
                     VVMMVEGAMADWSAVYLRQSLGAEAGLAGAGYAGFSLAMAMGRLTGDRLVSGLGPRVLL
                     GVGALLAAGGLGAALLLHHPVAAIVGFGCVGLGLSNLVPVLFSAAGRVSSIPAAVGIAA
                     VSTTGYGGFLVGPPLVGLLADWTRLPVALGLLVVLLGLIAAGARRVFPDGA"
     gene            complement(16140..18335)
                     /locus_tag="CYFUS_RS36760"
                     /old_locus_tag="CYFUS_007262"
     CDS             complement(16140..18335)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624822.1"
                     /locus_tag="CYFUS_RS36760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007262"
                     /product="M4 family metallopeptidase"
                     /protein_id="WP_232537015.1"
                     /transl_table=11
                     /translation="MSHRIRGVVGVTALSLLMSACTEGSGLEGSKAEGVKTLASALGNN
                     VVDKDEAGVARFIVGDLGAAPASSLAADLAPALATIAPQFRISPDNLRLTRSYKDAQGD
                     EHHRYQVSHNGRAIYGGELRLHARAGKIIAANTNVRGDLTGPEKAVVAPEAAAIAAAED
                     RDAPLSARTAAGEPELFYYRAGDKLLLVYEVRQTGTQADGTPVDDSVLINSLDGSIVQR
                     IPHVHTALDRKMYDGQTKSTLPGVLTRIEGAAPVADAVVNTNYDHLGTVYKCYSELFGR
                     DSINNAGATLISTVHHQVKYVNAFWNGTQMVYGDGDGVNASNLANSLDVTAHELTHAVT
                     EYESDLIYSGESGGLNESWSDIFGAVCEWYRDGKVVSAATWIVGDDVWTPSIPGDGLRY
                     MANPTQDGDSLDYYPDYSSGVDVHYSSGISNLAFYLLSQGGKHPGGKTTTEVTGIGIEK
                     AAKIFYKANADIMTASTSFEQAKVATEQAAQQLGYDAATIASVSNAWKAVGVGVPVPPP
                     PTSPIEKNVPANVEGAKGSKKYFDFDVPEGAYDLQVTLAGGTGDADLYVRYANAPTTSL
                     YDCRPYKSGNNESCTFAAPSNGKWYVLLNGYSAYSGATLTVTWKGGYTNIENRQKVEGL
                     SGTPGSERIFKLAVPARRNGGNNHVQIRLHGGTGNVDLYAQHGSAPNTFEYDCRGVNDH
                     NNETCNLNDVRPGNYYILVYGAKGGFENVTLEVLHQE"
     misc_feature    complement(18398..18411)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.01"
                     /tool="antismash"
     misc_feature    complement(18399..18412)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.34"
                     /tool="antismash"
     misc_feature    18399..18413
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.55"
                     /tool="antismash"
     misc_feature    18400..18413
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.7"
                     /tool="antismash"
     misc_feature    18401..18414
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.97"
                     /tool="antismash"
     misc_feature    18467..18482
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.72"
                     /tool="antismash"
     misc_feature    complement(18719..18732)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.7"
                     /tool="antismash"
     misc_feature    18719..18732
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.3"
                     /tool="antismash"
     gene            18784..20577
                     /locus_tag="CYFUS_RS36765"
                     /old_locus_tag="CYFUS_007263"
     CDS             18784..20577
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF027718.4"
                     /locus_tag="CYFUS_RS36765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007263"
                     /product="immunoglobulin-like domain-containing protein"
                     /protein_id="WP_232537865.1"
                     /transl_table=11
                     /translation="MISNPRHRTSSRPGARARFSWHSLMRCAPLLGALAACGPTDSAAP
                     REEQGIGQTARALESTLQASAETSVSTTTPPWSVDAQPTVAVGNGVYLVVWEMEGHDTP
                     DILAVRVRASDGALLDSSPLHIATGSQVSYLPSVAFDGANFLVTWTDLTSSPAIVGARV
                     RASDGALLDTEPLRISPPDFLPQYSPTVTFDGTNYLVFWHGYAWLGQGIADHRLQGIRI
                     RPSDGTRIESASFHVAVNEPAFHAASWGGASLVAWVDGGVKAARVDAAGQVLDTTPLNL
                     SPASATQVRVAARAGEFLVIFNEGSSLKARRVRASDGALLDASDILVGSGAEFPADTGW
                     NSASFSATFDGQDYRVLWQASRGGGRQLRTTRVSSSGTVEAGAEDGLATLHGGSGDWVG
                     IAAQSPSHFLVTYTQYDSSVENNRTRFRLVGPNDCAHDVSPPLVSCPATRRLECTYSGQ
                     TTVDMSVDDNCGIQFVSNTPQYFGQPGTWTHSVGAIDLAGNLTSCDTVWTVVDTRPPHL
                     SLNGSTSLSLPYNTPYQEPGATGGDECDGPYMDTWSWPNRIQVSGTVNSQVPGTYPLTY
                     RLTDGAGNTTTATRTVTVLAP"
     gene            complement(20636..21739)
                     /locus_tag="CYFUS_RS36770"
                     /old_locus_tag="CYFUS_007264"
     CDS             complement(20636..21739)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624824.1"
                     /locus_tag="CYFUS_RS36770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007264"
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="WP_095989447.1"
                     /transl_table=11
                     /translation="MAADALFRPFSYKSLHLKNRIVMAPMTRSFSPNGVPPSEVATYYR
                     RRAEGEVGLILSEGTVVARPSAKNDPNVPDFHGEQALAGWKRIIDEVHAAGGRMGPQIW
                     HVGSARNPQVKWAAPPPVDSPSGLSSPGKRFTEPMTESAIADTIAAFGKAAADAKRLGF
                     DVAEIHGAHGYLIDQFFWAGTNERTDVYGGASLAERTRFAVDVVKSMRAAVGEDFVIIL
                     RLSQWKQQDFNVKLAQTPKEMEAWLTPLVDAGVDILHCSQRRFWEPEFEGSDLNFAGWA
                     KKLTGRPTITVGSVGLAGEFLETLMKGAGSKPASIDNLLRRLEREEFDLVAVGRALISD
                     AQWARKVREGRDSELAAFDREALATLV"
     gene            21902..22039
                     /locus_tag="CYFUS_RS51990"
                     /old_locus_tag="CYFUS_007265"
     CDS             21902..22039
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624825.1"
                     /locus_tag="CYFUS_RS51990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_007265"
                     /product="hypothetical protein"
                     /protein_id="WP_198317012.1"
                     /transl_table=11
                     /translation="MSHASAVINLDEFRKRRESKPAAVRPMPTLGVWSPVWVWVMVWPA
                     "
     misc_feature    22888..22902
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.21"
                     /tool="antismash"
ORIGIN
        1 cagtgcacac ggcgcggggc gtaatgcagc cagaagatgg tttgtcccag cgccaggtgc
       61 cgccacaacc gcccagggct cgtgtcgtag ccgggggcgg gccggccgca cactccgcag
      121 cgaggcttgc gctggcgcgg gcgcacctcc accaccactc ccttggcctc cagccgggcc
      181 ccttgcacac tcagcccctg gatgcgcaac acccgcccca gcacctctcg cagccttggc
      241 cccgccacgc cccgcctccc cctccagcac cccgggggcg gcacgtattg caactccgcg
      301 acctggtctc ttcccagagc gacagcctct atcggcttct cgctccccat ctctcatcgg
      361 agaccctccc gtccacggcg ggaacgccca tttcggctac agaagatcca cttttctgct
      421 ccatcgacat gccgtcccac gacatgacga ggcccaccat acccacgatc cccacgatgg
      481 ccagccccac ggccaccacg gccgcggcaa ggggggcgac cgcggcaagc agcagcaatc
      541 cggcgccgaa gagggccgtc atcagcaacc ccttggcggc cccttccagg aagcaggaga
      601 ggcagaatcc ctctccgctc agggccatgt tgacgcccag ccccacggcc gtgcccacga
      661 cggcgcccag cagcagtgct ggcaaggcca ctccggccac ggccaccacc gccgccgccg
      721 ccgcgacgcc ggccaccacc gacagcacgc cccccccaac tccagagccc taacggatcc
      781 gttcggttga tcggatcgtt atgcgcgtag gcatagaagt gggtgccgtt gagccatttg
      841 agcgggtctg gcgaggtgta gcgcccgagc cgcggcgcat agtagcggaa gcggttgtag
      901 tgaagccccg tctcctcgtc atggtattgg ccgggcagcc gcagtgggtt gtctaccctg
      961 ccggagaccg aggccaggcc gaaagcacca tagacggcgg accagaccac gcggcccagc
     1021 cagtccgtaa tccgctcggg tgcgccctgg agattggtgt ggaagaggta aacctgtccg
     1081 tccacacgca tagccagcgg cacgtgggtg ccaggctggt agagatagtc ctggatggtg
     1141 acctgaccct gctcgcggcg ctcctctcgt accaggtgct cgccggccca caggtagcgg
     1201 acctctcgtc gagcggtgcg cttccacagg cgccggccga gtgcatcgta gccaaaggtc
     1261 acctcgagcc ccgcgggcgt gcgcgccctc accagcaggt ttcgagcgtc gtattcgaag
     1321 taccactgcc cggctggctc gtgcagcgag atgaggttgc ccctctcgtc atacgcacac
     1381 tgctgctcgc cctggtacag cagtctgtcg gcagcgtcga acgaggcctg ctccccattg
     1441 gccctcaccc ggttgccgca cgcatcgtag gcgaactcct cgtcgggcaa ccccgccgac
     1501 tgcgtcgcca gcagtctccc ctccgcgtcg taatggaaag agcgctccgc gtgctcggag
     1561 tctttcgtgg agagcaaccg tccctgctca tcatgcgtgt agtcctgccg gaagagcagc
     1621 gcgccgttgg ccccgccatg acggctttcg ctccactgcg gcagccccgc tttggagagg
     1681 cccacggagg tggtgacgcc attggccgca tggaactggt ggccccggtc gttcggcagg
     1741 tgttccatcg tgtggaggcc accgttccag tcggtcacct ccgcgagccg caggtcggcg
     1801 tcatagccat aacgcacctg ctcgcccgag ggcagcacca atgcggtgag caagcccgcc
     1861 tcgtcatagg tgtactcgat gacctgctcg tcctgtcgct cgcggacgag tttgccctgc
     1921 tcgtcgtagg tgaactccac ctctccttcg ggcccggctg cgcgcgtgac gcgtccccgg
     1981 gcatcctgcg tcaggtgcag caccacgcca tccgcgtagc ggatttctcg gtgcgacgtg
     2041 ccctcgtagg ccactgtgaa gagtggcatc tggcccaccg agcaggagag cagacgtcct
     2101 gacgcgtcgt aggtgtagtg ctccgccgag ccgtccgggc gctccacccg atgggggttg
     2161 ggccccgcgc cataggtgaa gcgggtgcgt cgcccgcctg gatccgtcag cgtggtgagg
     2221 cgctcccgct catcgtactc gaagcatgtg acccctccga gccggtcctg aagcaaggtg
     2281 ggtagcccag aagcctggtg ctccagcacg gtcgccgtct ggtcgggatg ggtgagcttt
     2341 cgtggctgtc cctgagcgtc gtaggagatg cgccacacgt gctgctggtc atcactgatc
     2401 tcgacgagtt tgctcccctg gtagcgcatt ccgaaccgca tgccagaggg gagggtgagc
     2461 gcttgcaggt gcccctcgga atcgttctcc atatgccagc ggcgattcag gggcgtggtg
     2521 acaccgccta cgtagccgag cgggtccagg tgcagccgcc ggacatggcc tcgtccgtcc
     2581 ctggcgagga tgtccccggt gagtggatcc cgttcggcct cctgccccag ggcattcaga
     2641 ttgcgcagca ggagttcccc cagctgaagt ctgcgcagtt ctctggtctg ctgctctccg
     2701 agcttgagca tgaagtctcc tcatgtcctt ggtggcaatc gaggggatgc ttcccgccct
     2761 ccctcgggcg tgtagtgaat tcgtaggatc tgctccggct gctcaccctg cagccagaag
     2821 cagtcgatgg ggccgaggac ttcccgcacg agggacgcgc tgctcgtgcg caggaagggg
     2881 cgtagcacgc gtggatcgta gaagcggaaa tacagctcct gccctgtcgc tccctccacc
     2941 atcagcagct tgcgcaggtg ccgccgcacc tcggcgaatg gttgggcaca agcaaggtag
     3001 atgccccaac tcttgcccca cccctccgcc agaagtgcgt ggagcaggcg gccctctctt
     3061 ggcagactca ccagataagg cgcgacctcg gcgagcactt cggcctgtgg gccctcatag
     3121 agggacttag agaactccac ggactcccga agcagcacgc ggacgcgctc gctcctggcg
     3181 gcgtcgagca cggccagcaa gggtaatgac tcgacctcaa gtacctccag caggcggctg
     3241 gcgagctgca cccgctccgg tgtcaggggc tccgcagggg gcgtcgcccc ttcgaagtaa
     3301 acggacaggt ccgtggtgcc ggcacggacc caggccccat ggtggatctg ggcctccttg
     3361 gtgatgcggc gcccatccag cagggtcccc gtcgcgctgt ccaggtcccg cagcaggcag
     3421 gtcattccat tccatacgag ctcgaagtgc agcgcggaca gatgcggatc gctcgcgaca
     3481 acgagaccgg cctgctcgcc ccgaccgacc cggagcactt gtcccggctc aagtacagcc
     3541 ctgtggaggg caggagcctt gaatcgtatt tcgacgataa gccgcgtgct catgaggcgg
     3601 tttttgtcac gaaggacgcg ccgctattag aggccgaact catacacccg gcctgagccg
     3661 gggcgccaat caagacagtg ggacacccgg cgacgacaac gccaccatgc gaggtcggat
     3721 ctcccagccg ggcagcgggc ttgccaccga taagcaccgt gggttctccc tgtgagatgg
     3781 aatcgggtgg accattacac acgagcatgt ccccgacccg ggccgctggt tggaagccga
     3841 tgaggaccga gggctctcct gccaccgtgg gcccgccgac atgcggcacg ggtcctggct
     3901 cgaccttcgg gcaggtatgc atatctgtaa tcctggctgc cggcggcatg gttcctcctc
     3961 gaggaccgtg ctcagacctc aagtcccctc cactttatca gttccggtgg gacgctccgc
     4021 tttatgtcag cccggacgcg ccgggcgcgg agactccatg gcggcggccc gacccagcga
     4081 ggggaacgtc cgccggttct cgtagaggat gaggacgccc atcaccacga gcaggcccgc
     4141 gaaggctcgc ttgagggtgg cctgggagat gaagcgcgaa agccaggtgc cgccgacgga
     4201 gcccgcgatg gccaggcccg tgaagagcgt gagggccccc cacgcgacgt tcacatgacc
     4261 gaggtagccc gcgaacccca cgaaggagtt gaaggcgatg acgagcaggc tcgtgcccac
     4321 cgcctgcttc atgggcagac cgacccgcag gacgagcacc ggcacgatga ggaatccccc
     4381 gccaactccg accaaccccg tgagcgcgcc cacgccgagc gcggacgcgg cgatgagggg
     4441 aaaggaggcc gcgcgcggct cggctccggt ggccggggtg gtgagctcgc gccgggcgtt
     4501 gcgcgccatg aagaccgccg ccaccaacat caccgtggcg aagagcacca gttgcacggt
     4561 gcccggaagg aagaccgaca gacgcgcgcc gacgaaggtg ccccccatcg ccatcgcccc
     4621 gaagacgagc gcggcccgga gctggaggtt gcccgcgcgc cagtgtccga tggcgccgaa
     4681 gaggctcgtg gtgcccacga tcgccagccc catggcgatg gactccttgg gctcgaagcc
     4741 cagcacgtag acgaggatcg gcaccgtgag gatggagccc cctcccccga gcagccccag
     4801 ggacacaccg atgagcgcgg cgagcgcgaa gcccaccagg ggcatggccg gagggacgaa
     4861 cagcgcgagc acgccatgaa ggcccgggct cacgtgggcg gaactcccga gccgctcggc
     4921 gcggcggacc cctcgcgtac cgccagcatg ccccccttga ggttgtagag acggccaaag
     4981 ccgcgccggg ccaggatctc ggcggccgtc acggaccgcc ggcccgagcg gcagatgagc
     5041 agcagcggct ccgcgcggga ccaggtggcg cacgcgtcct cgagcgtgcc caggggaacg
     5101 agctcggccc gggacagatg gcccaggggt ccctcgaact catcgggctc gcgcacgtcg
     5161 atgcgccgca cctcgggccc cagggtgtcg agctgctcgg gaagcagatc caggaagaga
     5221 ggagaggaca tggtcgcgcg ttccttacga gtccaggcgc ccacaggagc ggttggcggg
     5281 cacggccacg tccagcttcc ggggcatggg caggtggagg ttgcccatga ggtggatgaa
     5341 ctcctcgcgg ccgcgtcccg cgaggcgcgg gttgtgccgc ttctcctcgc cgatggtcgt
     5401 caccgtccgg cccaggtagt cgtgcccggg gtagacgagc gtgtcgtccg gcagggcgaa
     5461 gagcacccgg gtgatggagt cgtggagatg gcccgcgtcc ccattctgga agtccgtccg
     5521 cccggtgccg cggatgagca gcgtgtcccc cgtgaacacc cgctccccca ggcggtagct
     5581 cacgccgtca tcggtatgtc ccggagtgcc gagcacgcgc accaccaggg ccccgacgca
     5641 cacctcgtcc ccatgccgca catggagatc ggcgcacgac gccccccgct cactggccac
     5701 caccgtgcac ccggtacgct cgcgcagtcg ccccgcggag gtgatgtggt ccgcgtgcac
     5761 gtgcgtctcc agcacatggg tgaggcgcag gccgagctcg cgcaccagcg tgagatccct
     5821 ctccacctgc tcgagcaccg gatcgatgag agcggcctgc cccgaggacg gatctcccag
     5881 gaggtaggta taggtcgagg actcggcgtc gaagagctga cggaagatca tgccccgcgc
     5941 tcattgcgat caccgtgcca gggccgcccc tcctggagga acgcccggac gccccctggt
     6001 tgaaacaccg cgtgaaacac cgggaaacgc gctaccgcgt gaccttgtcc ccgagcgcgc
     6061 gcaaccggcg ccacagggtg acgcggctga tgcccagcag gcgggcggcc tgggtgtggt
     6121 tgccgcccgc ctcctccagc gcggcgcgca gggtggccgg atcatgatcg tccaccggac
     6181 gaaccagggc gctggccgga cgccccggct ggagggacgc ggagggcacg cggggctcgg
     6241 cggatgggcg gggctcggag aactcgggcg gcagatcggc ctcgtgcagc agggggccct
     6301 ctccgatgac gaaggcgtac tccatcacgt tgcgcagctc gcgcacgttg cccggccagc
     6361 cgtggcgctc cagcagccgc tgggctccgg gggagatgcg ctccacgtgg cgcgagccct
     6421 ggcgctccaa ctcatcgagg aagcgccggg ccaggggcag gatgtccccg cgccgctcgc
     6481 gcagcgaagg caggaagagc ggcaccacgc gcagccggta catcaggtcc gcgcggaagc
     6541 ggccctcctc cacctcgcgg cgcagcgcgc ggtgggtggc ggcgacgatg cgcacgttga
     6601 ccggcaccga cgcgcgcccg cccacgggaa tgacggtgcg cgtctcgagc acccgcagca
     6661 gcttgccctg gagctccagg ggaatctccc ccacctcgtc gaggaagagc gtccccctgt
     6721 ccgcgagccg gaagtggccc gggctgtcgc gcaccgcgcc ggtgaaggcg ccgcgcacgt
     6781 ggccgaacag ctcgctctcc aacaggctgg ggggaagggc cgcgcagttg atggcccgga
     6841 agggaccctt gcgccgcgcg gagatggcgt gcagggcatt ggccaccagc tccttgcccg
     6901 taccggactc gccccgcacc agcacgctcg actcggtgcg agccaccttc tccacgatgc
     6961 gaaacaggcg cttcatcccc ggatcgcgcg tccacagccc gtggaaggtc tcctcgacgt
     7021 ccccctgcgg cgaggccccc gcctcccccg gcgagagcaa caccaaccac ccgagccgct
     7081 tcgcgccctc gtcgagcgcc acggcgcgca cgcggatgga gcaccccgcc ccgccttccc
     7141 cgcgaggcat gacctccagg ggccgcccgt gggacagcag cgcctcgagg ctcccttgtc
     7201 cctcgcggaa gcggagcacc tcggcgaggg gccgccccgg gaacagctca ccgaggccga
     7261 gtcggacccg cgcctggggc gtggcatcgg ccacacgcag ccgctcatcc acgagcagca
     7321 cgtcaccggc cagggcctcc agggcggagc gcaccaggag cgtgttgagg gagggcctgg
     7381 aggaggacat ggggcgagag gggcgcgcta ggcccgtccg cgtagcatca acttccagta
     7441 gagctgcggc aagccgtact tcttgagcag ccacatgtca tgccgttcct tgatggaatc
     7501 gatgaacggg aaggtgggcg tgggcttgcc ctcgtagccg aactccgcga gcagcagctt
     7561 gccgtaggcc gtggtgagcg ggcaggaggc gtagccatcg tacttcgcgg cgggctcgcg
     7621 ccccgccatg acggccagca ggttctccac cagcacgggc gcctccttgc ggatggccgc
     7681 gccggtgcgc gaggtgggaa ggtccgaggc atctcccagc gcgaacacct ccgggtagtc
     7741 cgggtggcgc agcgtgtact tgtccgcctt cacccagccc cggttggggc cgtcctgcca
     7801 ggccaggggg ctcgccttga tgaagtccgg cgcgctctgg ggtgggcaca cgtggagcag
     7861 ctcgtaggcg aggacgatct gctcggcgcc tccatccgcc cgggtgtgcc ggaagacggc
     7921 ctcgttgcgc gctccgcgca cctccaccag gtcgtgctgg aagcgcgtgt cgatgccata
     7981 gcgctccacc acctgctcca gcaccgccgc gtactccttc accccgaaga tggccttgcc
     8041 cgcggaggcg aagacgacgt gcgcggcctt gtcgaggccc cgcttccgga agtggtccgc
     8101 ggccaggtac atgatcttct gcggcgcacc cgcgcacttc accggcgtgg aggggtgggt
     8161 gaagagggca gtgcccccct ggaaggcacg gagcatgtcc cacgtcttgg gggcataacg
     8221 cgcctcgtag ttgctggaga cattgggccg cgactccagc gcctcgcgca gcccgcgcac
     8281 cttgtcccag tcgagctgga tgcccggcgc caccacgagg aagtcatagc cgagctccag
     8341 accgccccgg gtgctcacct tccgggccac cgggtccacg tcccgtgccc agtcctggat
     8401 ccacttcact cccttgggaa tgaggcgggc ctcgtcgcgc acggtgtcct ccacgcgcgc
     8461 ctcgccggcc cccaccaacg tccagagcgg ctggtagtag tgctgggcgc tgggctcgat
     8521 gatcgccacg tccttctgcc cggcgcgggc cagccgcgcg gccacgctga tgcccgcggt
     8581 ccccccaccg atgatgagaa tccgatgcct cgaggcgctg ggaatccggg ccagccgcgc
     8641 gccctcctgc cctgcgcgga cgtgttcgct catcgcttcg ctcatgtcac tcccccgctg
     8701 tgggaaccat cctgggtgga tggaaggacc ctgacccagt gcagcactcg tgccacccct
     8761 ctcctccgag aacacacgag cgccccatcc tccggttgtt tcaagatgtg tttcagggtg
     8821 tttcacgcaa accgttcacc ctccgcacct cgagccaagc actcactggc ctctaatcgc
     8881 tgtccgtgcc ttgctccatc gcgctccagg aggacgaatg aatcccccac aagacattcc
     8941 cacgcacgtg gcccccgcag tcgcgcgcta cacggacgcc gtcgtgaagc gactccaggc
     9001 cgtgctcggc gacgcgctgc tgggcgtcta cctcatcggc tcgaacagcc tgggggggta
     9061 tgaagccgga ccgagcgaca tcgacctcat cgccatctgc gctcggcccg tggagctcgc
     9121 gacgaaagag gccctcgcga gggagctgga tcaccgcgcc ctgccctgtc ccgcccgggg
     9181 cctggagttc gtcctgtacc ccaaggacac cgtctcgcgg ccgaccccga gcccccgctt
     9241 cgagctgaac ctcaacaccg gcgccggaat gggccaccgg ttcaccgtcc gcccggaaga
     9301 cgagtccccg cactggttcg tcatcgacct cgacatcgcc cgccagcacg gggtgagact
     9361 ggccggaccg cccgccaacg agctgctcgc accccaggac aagcgctggg tgctcgacgc
     9421 catccgcacc tcgctcgcgt ggcactcgcg ggaggagccg gcgagcgcca acaacgtgct
     9481 caacgcctgc cgggcctggc ggtatgccga ggagggcgta tggagcacca aactggccgc
     9541 ggccacatgg gcccgggagc ggctggagga gccgtccctc atcgatgccg cactcgccac
     9601 tcggcggggt caacccggcc ccgcgctgac cccggaggca gtgcacgccc tggtgcaacg
     9661 ggttctccgc gtcgtcgagc gcgccatgcc ccgagacaac ccatgaagac gaggggcctg
     9721 gaactcccga gggaattcca ggccccttcg tgcccggacc ggctacccgc cgggcacctc
     9781 accacgatga ctcagtagca gtacttcgga ggacacggcg tgcagtaggc cgacgtgggc
     9841 tccaggatgc cgccccccgt cacggactcc agaacgctgt cgtccagggc aaaggcggac
     9901 gccgggttgg cgggcagcgc ggcacgctcc tccgccgaca ggctgttgaa gtactcgggg
     9961 tcacgccagg cacggaggat atgctcggtg ttcgacttgc tcatgggggc tctcccttgg
    10021 atgggggttg gatcctcgac tgctccgaat gccgccaacc cttcggcttc ggaatcgtgt
    10081 ggcccggcgg cgcgagcgcg agcagggaag gcaggcgttc cggcgcggcc agacgcgcca
    10141 gcccgtagcc gatgcccgcg agccccacca tgagccccgg cgtctcgatg ttgcgttgca
    10201 gcccgaagag gcagccccgc tcgtccagga cgcgcagcac cgtgcgggcc cgctggtaga
    10261 cctgatgctc cagcgcctcg tctcccagga cgcgcgccgc ctccaggagg aaatccaggt
    10321 tgcccaggtc gccatggcac agggagtggt tctggccgaa accgcccgcg agcgtcgtgg
    10381 ccacggcgtg ggcgagctcc tcgcgcaccc gggcatcgtc atacatgggc agccccgaca
    10441 gccgcgccag accgatgccc ggcgcgccat ggcaccacgc ggtcatgaag tgcatcccac
    10501 cgccatgcgg ccccgccagc tcggcggcgc ccgcgcgcag atccggccag ttgcgctccg
    10561 cggcggagaa cagcccccgc tcgaactcga tgccctcgcg cgccatccgg ccgaagcgct
    10621 cgtcgcccgt ggccgccgcg agccgcagca gcgccaggct gatgcccgcg gcgccgtggg
    10681 acattcccgc cagggcgagc tgtcccgcca gcggcaccac ccaccccatg ccccgctcct
    10741 ggcgccgggc ggagtcgagc aggcgctctc cacaggcgcg ggcggccttc cacagcagct
    10801 ccgacggccg gtgctccgcg agcgtgagca gggcgatgag gcaccccgcc gagcccacgc
    10861 ccaggtcgag catctcatcg cgctcgatca gcgccggcag ccgctccaga tagtgctcgg
    10921 ccctgtccag cgtccgcgcg tccgcccaca gcacgcccag gtgcgtgagt ccgtagagga
    10981 cgccgcccca gccattgagc aggcccagtc cccgtacctg ggaggcatcc agttcgatct
    11041 gatgctcctg ggcgcacagg gccatccggg cggtgcgggt gaaggactcc tcgcccgtgg
    11101 cggcccccag gtagccgagg aacagggcga tgccccccag cccctggtag agatcggccc
    11161 ccgcgtgcgc gagctgccat ccgcccgcat cggcgtagtc gagcgtcaac cagtgggcct
    11221 cctccggtcc acggaggctc aaccccacga gcttctcccc gatgcgccgg gccgccgcga
    11281 gcaactcctc cctccccgcg cgctcgcccg gctccgggac cggataggag ggacgctcgc
    11341 cacccggctc ccccaggcgc agcgcatcga gcgcgcggtg gatgatccaa cgctggcgtt
    11401 cgagatcctc gtcggacagg agcgccaccc ggcgccgcac gcgctccaga ccaggagtct
    11461 ccaggaaatc ctccaggcgc gcccccgagc tcgtccagac gtgccgcgtg ccgggcaggg
    11521 tcgtgaacag ggggacgtct ccgcgcagga gatcctcgag ctcgaaggga atcagggacg
    11581 ccaggaaggg gcgctccacg gcgcccttcc agaggtgctc gaggaagcac tgacgctcca
    11641 gggcatcccc gagcgcatgg ggatggaagc tctcgagcaa cagggagcca tagacggacg
    11701 tgtggcggaa gacgacccgc accggcgcct ccgcgaacgc cgcgaggggc ccgtccccgg
    11761 cgagcagcgc ctctcgccgc cgcagcagca ggcggtacat gcgcgagaag ccctcggaca
    11821 acgcgtcggc gtagtcgagc agcgaggcgt ccaccccctc caggcgcgga cggttgtggg
    11881 agccggggac ctccacctgg cggcgctcga accgcatgcg atccgtgccc cgctcgaccg
    11941 gcatgaggaa ggcctgggga gtgagctgcc cggcgctgga accgaggcca ctgatgtcca
    12001 ccccggggcg ctcccgggtg ccccaggtgc gttggggcag cagcccgctc ttgagcaccg
    12061 actccccgag gggcgctccc ggatggcgct cggtgtcccg ctgttcgcgc acgcgcacgg
    12121 ggggatggaa gagcgtctcg aggtccacca gcacggggtg ctcgccggag gcgatcaggt
    12181 tctcgtgatg gaaatcggtg gcgtcgagca cgtacagcag ggcgatgaag ccgccctggc
    12241 gcagatagaa gcggcgcacc tcctcggccg aggaacaggg ggccggggtc acgaactcca
    12301 cccagccgtg gtctccgcgg tcgagcacct cgagggtgcg cggggcgggc tcgaggccct
    12361 gctgcgccaa ccaggacagg agccgctgga aggcggcctc ggtggcgagg gacctgggct
    12421 tgtagaccag gcgcgtgccc gactcgaagc gcagcaggaa gacaccccgg ccaccccggt
    12481 gggagtccga gactccgcct tcggcttcca ccagccggcc caacggcacg cctcccgaga
    12541 agcggcgctg gagctccggc gcgtcctcgc ggaagtggcg cagcagctcc acccccgcgc
    12601 gctcccagtg ggcgatgcac tcgacgagct gacgggccag gacggggtag cgcgccagga
    12661 tctccagggc cacctcgcgt cggcgcaggg agtgggcgaa gtcctggaag cgcgcccgcg
    12721 gcgtgtcgcc cgtgagccgc tcctgcaact gcgccgcgtg caactccacg acgagggtcc
    12781 ggctgagcaa cggagtcagc agcgtgggca gatggcccag cagctcccgc ccgagggtct
    12841 cgggctcgaa gagcgccccg ggaaacgacg tctcgagttc gcccagtccg cgcaggagac
    12901 gggcgaggcc gcttcgcacc aacggctcgg ccagggcgag gaacgcggag cgctccggcc
    12961 cccccgcgcg ctcgggccag gagaagggct cggagacggg ctccacgtag gcccgttcga
    13021 tctcctggag ccacgcgggg gcggactcca tggacgaccg caaggcctcg ggggacaggc
    13081 ccagcaggga gaggaagtcc tcctcggtga gtccatcggc cgcgagccgg cgtgtccacc
    13141 actcctcccg gacgaagggc tcctgcgcgc gccagcgttc ggcgcggcga cgggcccgct
    13201 cccccgctgt cctgaccggg ccgccgtgac gccgcagggc aaggatgcgc tcgctcagct
    13261 cggttccgag ataccagcgc gaggcagcag gtgtttcccc tcccttcgcg ccctgcgcat
    13321 cggcgtcatt gtcggaggag gacacgcggg ctccattcac gaacgagggt tccggggaag
    13381 aaaggctctt cccgccctgc ccaatctacc cgaacgctcc cacgtgaagt cgcccgtctt
    13441 cacgaaagaa cactcccgta gatccgcggg gcggctcgcg cgttacagcc ccggcgcgcg
    13501 ctggattgtc agcacccctc cttccctcac cggactcccc gtcatgaccc tgaagacctt
    13561 ctcgcgcccc gcgctcgggg ccgcgctcgc cctctccatg ttcgccgcgc cccacgccct
    13621 cgcgggtgac cctcccccgg ccccgcccgc ccaggtccag ccccaacaac agacgccccc
    13681 gcctcccgcg cccccacggc aggaggccca gccgaggatc gatctggtct tcgtcctgga
    13741 caccacgggc tccatgagcg ggctcatcga gggcgccaag cagaagatct tctccatcgc
    13801 gtcgcgcatc gcccagggca agcccacgcc tcgggtgcgg gtgggactgg tggcctaccg
    13861 ggacgtgggc gacgagtacg tcacccggtg gacggatctc acggacgacc tggatggcgt
    13921 cttcacgcac ctgcgccagc tccgggcgga tggcggcggg gacacgcccg agcacgtggg
    13981 acgcggcctg ggcgaggcgg tgtcgaagct gtcgtgggac ccgagccgcg agacgatgaa
    14041 gctcatcttc ctggtgggag acgcgccgcc cgcgcagcgc gagaagcaat ggaacttcca
    14101 gcactgggtg aagcgggcgg cggagcagca catcgtggtg aacacggtgc gctgtggaag
    14161 cgaccccgag acccagacgc aatggaagta cgcggcgaag acgacggacg ggttgtacga
    14221 atccctggag cagtcgggcg gcatggcggc ggtggtgacg ccctatgacg cggagctggc
    14281 ccgggtgaac gcggagctgg cgcgcaagac gatgtacgcg gggaagaagg aagcgcgcga
    14341 ggcgaaccag gcccgggccg gacagatggc ggagctgccc gcggaagccg cggccgagcg
    14401 catccagttc atgaagacga cccggggccg gggcaagggg gccgccgccg ccgcggtgag
    14461 cagcgcgccc gcgccggtgc agggcgcggt ggacctgacg gcgcagcccg aggccctcgc
    14521 cggcgtggcg gacgacgagc tgcccgggga actgcgcgcg ctggacacgg cgggccgcgc
    14581 ggcgaaggtc aaacaactcg ccgacgagcg caaggacctg gaggagaagg ccgcgaagct
    14641 ggcggcggag cgcgactcct ggcgcgcgaa gaacgtggcc gacaagcagg acgccttcga
    14701 cgccaacgtc atgaagagcg tgaaggcgaa ggccgccgcg cacgggctga gctactgaac
    14761 cctccccttg catgaaccag catactcgcg cattatcatg caaaacaacg cactaatgcg
    14821 gagattcatg cgaacgaaaa gcgctggttc atgcgtcatc ttgccgattt gggagttctg
    14881 gtgcccgaga ggagggcgct catgagggcc tccccactcg aagtcccggc gcgcgccgag
    14941 cccaccccgg gcgaggcccg cgccgcggtc tccaccgtct tcttcatcaa tggtttcgtc
    15001 ttcgcgagct gggtgccgca catccccacg gtgcagaacc ggctggggtt gagcacgagc
    15061 ctgctgggac tggcgctgtt gggggtggcg gcgggcgcgc tggtggccat gcccgtgacg
    15121 ggagcgctgg tgtcgcgctg gggcagccgc ttcgtcacgc tcgtgagcgc gctgctgctg
    15181 tgcgccctgg tggtgttgcc cgtgcgcgcg ctcgacttcc cgtccctggt gctggcgctg
    15241 gtgtcgctcg gggccgccaa cggctccatg gacgtggcga tgaacgccca cgccgtcgcc
    15301 gtggagcgcc gggtgggaag aaccatcatg tcctcgttcc atggcctgtt cagcctgggc
    15361 ggcctggcgg gcgcgggagg ctccgtgctg ctgctctccc gggggatgcc gcccgagacg
    15421 cacctgctgg gagtggcggc gttcgggggc acggcggtgc tcgcctgcgc gcgcttcctg
    15481 ctgcccgcct cggcggatgg gacgggggcc gcgcatgcct tcgcgctgcc gcgggggccg
    15541 ctgctcgtgt tcggcgcagc ggccttcgtg gtgatgatgg tggagggagc catggcggac
    15601 tggagcgccg tctacctgcg ccaatccctg ggggccgagg cgggactcgc gggcgcgggc
    15661 tacgcgggct tctcgctggc catggcgatg gggcggctga cgggggaccg gctcgtcagc
    15721 ggcctgggcc cgagggtgct gctcggcgtg ggagccctgc tggccgccgg gggactcggg
    15781 gccgcgctgc tcttgcacca cccggtggcg gccatcgtgg ggttcgggtg cgtggggctc
    15841 ggcctgtcca acctcgtccc cgtgctgttc agcgcggcgg gccgggtctc ctccattccc
    15901 gccgcggtgg gcatcgcggc ggtgtccacg acgggctacg gcggcttcct cgtgggccct
    15961 ccgctcgtcg gactgctcgc ggactggacg cgcctgcccg tggccctggg actgctcgtg
    16021 gtgctcctcg gcctcatcgc cgcgggggcg cgccgcgtgt tcccggacgg ggcctgaaaa
    16081 cgagaagggg gtgggccgtg agacccaccc ccctcagcga ctacctcgag cgcttcggat
    16141 tactcctggt ggaggacctc gagcgtcacg ttctcgaagc cacccttcgc gccgtacacc
    16201 aggatgtagt agttgcccgg gcgcacgtcg ttgaggttgc acgtctcgtt gttgtggtcg
    16261 ttcacgccgc ggcagtcgta ctcgaaggtg ttgggcgccg agccgtgctg cgcgtacagg
    16321 tccacgttgc ccgtgccgcc gtgcaggcgg atctgcacgt ggttgttgcc accgttcctg
    16381 cgagcgggaa ccgcgagctt gaagatgcgc tcggagcccg gcgtaccgga gaggccttcc
    16441 accttctggc ggttctcgat gttggtgtag ccacccttcc aggtcaccgt cagcgtggcg
    16501 ccggagtagg cgctgtagcc gttgagcagg acgtaccact tgccattgct cggcgcggcg
    16561 aaggtgcacg actcgttgtt gccggacttg tagggacggc agtcgtacag gctggtggtg
    16621 ggcgcgttgg cgtagcgcac gtacaggtcc gcgtcgcccg tgccaccggc cagggtgacc
    16681 tggaggtcat acgcaccctc gggcacgtcg aagtcgaagt acttcttgga gcccttcgcg
    16741 ccctcgacgt tggccggcac gttcttctcg atcggcgacg tgggcggagg aggcacgggc
    16801 acgcccacac ccacggcctt ccaggcgttg gagacggagg cgatggtggc cgcgtcatag
    16861 ccgagctgct gcgcggcctg ctcggtggcg accttggcct gctcgaacga ggtgctcgcc
    16921 gtcatgatgt cggcgttggc cttgtagaag atcttcgcgg ccttctcgat gccgatgccc
    16981 gtcacttccg tggtcgtctt gcccccgggg tgcttgccac cctggctcag caggtagaag
    17041 gccaggttgg agatgcccga gctgtagtgc acgtccacgc cggaggagta gtccgggtag
    17101 tagtccagcg agtcaccgtc ctgggtgggg ttggccatgt agcgcaggcc gtcgccgggg
    17161 atggacggcg tccacacgtc gtcaccgacg atccacgtgg cggcgctgac gaccttgccg
    17221 tcccggtacc actcgcacac ggcgccgaag atgtcggacc aggactcgtt gagaccaccg
    17281 gactcgcccg agtagatgag atccgactcg tactcggtca cggcgtgggt gagctcgtgc
    17341 gcggtgacgt ccagcgagtt ggccaggttg ctggcgttga cgccgtcacc gtcgccgtag
    17401 accatctggg tgccgttcca gaaggcgttc acgtacttca cctggtggtg cacggtgctg
    17461 atgagcgtgg cgcccgcgtt gttgatggag tcgcggccga acagctcgct gtagcacttg
    17521 tagacggtgc ccaggtggtc gtagttggtg ttgacgaccg cgtcggccac gggagccgcg
    17581 ccctcgatgc gcgtcaggac acccggcagg gtgctcttgg tctggccgtc gtacatcttg
    17641 cggtccaggg ccgtgtgcac gtgcgggatg cgctggacga tggagccatc cagcgagttg
    17701 atgagcaccg agtcgtccac cggcgtgccg tccgcctgcg tccccgtctg gcggacctca
    17761 tagacgagca ggagcttgtc gcccgcgcgg tagtagaaga gctccggctc gccggcggcg
    17821 gtgcgcgcgg acagcggggc gtcacggtcc tcggcggccg cgatggcggc ggcctcggga
    17881 gccaccaccg ccttctccgg gcccgtcagg tcgccgcgca cgttggtgtt ggcggcgatg
    17941 atcttcccgg cgcgcgcgtg caggcgcagc tcgccaccgt agatggcccg cccgttgtgg
    18001 ctgacctggt agcggtggtg ctcatcaccc tgcgcgtcct tgtaggagcg cgtgagccgc
    18061 aggttgtccg ggctgatgcg gaactggggc gcgatggtcg ccagggccgg agcgaggtcc
    18121 gcggccagcg aggaggccgg ggcggcgccc aggtcgccca cgatgaaccg ggccactccc
    18181 gcctcatcct tgtccacgac gttgttgcca agcgccgacg ccaaagtctt gacaccctcg
    18241 gccttggacc cctccaggcc gctgccttcg gtgcacgcgc tcatcaacaa cgacagggcg
    18301 gtgactccca cgactccgcg aattcgatga ctcactgaac tgcctccggt cactggaaca
    18361 attggggaac gggcatttcc agtgagctgt gtataactgc tttttacaaa atagggaact
    18421 tattacgaca tcatcgttca ttatcattta tcgagaatgg agaattttga ccgttcggtc
    18481 agggtgcaac ggagctcgtg aaatccgagg gagccccctt tgactcgaag cgcatctttt
    18541 gctaggcgcc gggcccattg gcgaaggcgg aaggaaggcc cccgcgcggt gtctgtgtat
    18601 ggcttgagcc gggcgccgcg cgtggaatct tccgtgggga aggaagccac ccggaggagg
    18661 gcctcatgac gcgcctggct gtcattgaag gcggagtcca acaccgcacg cggagtggga
    18721 aacgtatgtt agggtttgtc cgccctaccc caacatcgcc atcacaggag gtccttcccc
    18781 ttggtgattt ccaaccctcg tcaccgcacg agctcccgcc cgggcgctcg cgcgcgcttc
    18841 tcctggcatt ccctgatgcg ctgcgccccg ctgctgggcg cgctcgccgc gtgtggtccg
    18901 acggactccg ccgctccccg agaggagcaa ggcattggcc agacagcccg ggcactcgag
    18961 tccacgctcc aggcctcggc cgaaacgtcc gtgagcacca cgacgccccc ctggtccgtc
    19021 gacgcccagc ccacggtggc cgtgggcaat ggcgtctacc tcgtcgtctg ggagatggag
    19081 ggccacgaca ctcccgacat cctcgccgtg cgggtgcgcg cctcggacgg cgcgctgttg
    19141 gactcctcgc cccttcacat cgccacgggc agccaggtct cctacctgcc ctcggtggcc
    19201 ttcgacggag ccaacttcct ggtgacctgg acggacctca cctcgagccc ggccatcgtg
    19261 ggagcacgcg tgcgggcctc ggatggcgcg ctgctcgata cggagcccct gcgcatcagc
    19321 ccaccggatt tcctgcccca gtactcaccg accgtgacgt tcgacgggac gaactacctg
    19381 gtgttctggc acggctacgc ctggctcggc cagggcatcg cggaccacag gctccagggc
    19441 atccggatcc gtccctcgga cggcacgcgc atcgagtccg cctccttcca cgtcgccgtg
    19501 aacgagcccg ccttccatgc cgcctcgtgg ggaggcgcga gcctggtggc gtgggtcgac
    19561 ggcggggtga aggcggcccg cgtcgacgcg gcgggacagg tgctcgacac cactcccctg
    19621 aacctctccc cggcgtccgc gacccaggtc cgggtcgccg cgcgggcggg cgagttcctc
    19681 gtgatcttca acgagggctc atccttgaag gcccggcgcg tgcgcgcctc ggatggggcg
    19741 ctgctcgacg cctcggacat cctcgtgggc tccggagccg agttccccgc ggacaccggc
    19801 tggaacagcg cgtccttcag cgcgaccttc gatggacagg actaccgggt gctctggcag
    19861 gcgtcccgcg gcggaggtcg ccagctgcgc accacgcggg tgtcctcctc ggggacggtc
    19921 gaagcgggcg cggaggatgg gctcgccacg ctccatggag gctccgggga ttgggtgggc
    19981 atcgccgcgc agagcccctc ccacttcctg gtgacctata ctcagtatga ttcgtcggtg
    20041 gagaacaacc gcacccgctt ccggctcgtc ggcccgaatg actgcgccca cgacgtgtca
    20101 ccgccgctcg tgagctgtcc ggccacgcgc cggctggaat gcacctacag cggccagacc
    20161 accgtggaca tgagcgtcga cgacaactgc ggaatccagt tcgtgagcaa tacgccgcaa
    20221 tacttcggtc aaccgggcac ctggacccac tcggtcggcg ccatcgacct cgccggcaac
    20281 ctgacgagct gtgacacggt gtggacggtc gtcgatacgc gcccgcccca cctgagcctc
    20341 aacggctcga cgagcctctc cctgccctac aacacgccct accaggagcc aggggccacg
    20401 ggtggcgacg agtgcgacgg tccctacatg gacacctggt cctggccgaa ccggattcag
    20461 gtctccggca cggtcaactc ccaggtaccg ggcacctatc ccctcaccta ccgcctcacg
    20521 gacggcgccg gcaacacgac caccgccacg cgcaccgtga cggtcctcgc gccgtagcca
    20581 ggcctcccca cgcgggcggc ggcgggagcg gacttccgcc ctcgccgccg cgggctcaca
    20641 ccagcgtggc gagcgcttcg cgatcgaagg cggccagctc cgagtcgcgg ccctcgcgca
    20701 ccttgcgcgc ccactgcgcg tccgagatga gcgcgcgacc caccgccacc aggtcgaact
    20761 cctcccgctc caggcgccgc agcaggttgt cgatcgacgc gggcttggag cccgcgccct
    20821 tcatgagggt ctcgaggaac tcgcccgcca gccccaccga gcccacggtg atggtgggcc
    20881 tgccggtgag cttcttcgcc cagccggcga agttgaggtc cgagccctcg aactccggct
    20941 cccagaagcg gcgctgggag cagtggagga tgtccacgcc cgcgtcgacg agcggcgtga
    21001 gccacgcctc catctccttg ggcgtctggg cgagcttcac gttgaagtcc tgctgcttcc
    21061 actgggacag gcgcaggatg atgacgaagt cctcgcccac cgcggcgcgc atggacttca
    21121 ccacgtcgac ggcgaagcgg gtgcgctcgg cgagcgaggc gccgccatag acgtcggtgc
    21181 gctcgttcgt gcccgcccag aagaattgat cgatgaggta gccgtgggcg ccgtggatct
    21241 ccgccacgtc gaagcccagc cgcttggcgt ccgcggcggc cttgccgaag gcggcgatgg
    21301 tgtccgcgat ggccgactcc gtcatcggct cggtgaagcg cttgccgggc gaggacaggc
    21361 ccgaggggct atccaccgga ggcggagcgg cccacttcac ctgggggttg cgcgccgagc
    21421 ccacgtgcca gatctgcgga cccatgcgtc caccggcggc atgcacctcg tcgatgatgc
    21481 gcttccagcc ggccagcgcc tgctccccgt ggaagtccgg cacgttggga tcgttcttgg
    21541 ccgagggccg ggccacgacg gtgccctcgg acaggatgag gcccacctcg ccctcggcgc
    21601 ggcggcggta gtaggtggcg acctcggacg gcggcacgcc attgggcgag aaggaccggg
    21661 tcatgggcgc catgacgatg cggttcttga gatgaaggga cttgtaggag aagggtcgga
    21721 acagagcatc tgcggccacg gggaacggac ctccggttca gcggtgttcg ggcgcgcctt
    21781 ataacggcct ccccctcccc ccgccgcacc ctctccgttt tggcggacga aaatccgcgc
    21841 aaccggcgga cggctccttc cgacaataag gaaggatttc cttaccgaac cggtgtccgc
    21901 catgagccac gcctccgccg tcatcaacct ggatgagttc cgcaagcgcc gtgagagcaa
    21961 gcccgccgcc gtgcgtccca tgcccacgct gggtgtctgg tcgccggtgt gggtgtgggt
    22021 gatggtctgg cccgcgtgaa gctcagcgct cctcgggggg aggaacgagc gagaggatga
    22081 cggcaagcag ctcggagcgc tcgatgggct tgggcacgtg ggccttgaag ccggcgagca
    22141 acgcccgggt gcgatcctcc gcgcgggcgt aggcggtgag cgccacggcg gggatgcggc
    22201 cgccctcgga cgcgggaagg gcgcgcacct tgcggatgaa ggcatggcca tcctcgcccg
    22261 gcatgccgat gtcggagatg agcaggtggg gccgcgtctg gaggagcacg ctcaggccct
    22321 cggcggccga ggccgcggtc tccacccgca tgcgacaccc ctcgagcagc gtgcgcagca
    22381 actcgcgcgt gtccgcctcg tcgtccacga gcagcacccg caggccctcg agctggggcg
    22441 ggcatctcag gtcgggctcg tcgcgcgagc ccgtggcgga ggaggcacct gactccttgc
    22501 gccgcaccac ggccgtgggc agccgcaccg tgaaggtggc gccccggccc tcgccctcgc
    22561 tgaacgcatc gatcgtgccg ccgtgggctt ccaccaggtg cttgacgatg gacaggccca
    22621 ggcccaggcc cccgtacttg cgcgcgacac tgccctccgc ctgacggaag cgctcgaaga
    22681 cgtgcggcag gaagtccacc ggaatgccct tgccggagtc cgcgacgacg atctccaccg
    22741 aggagtcgcg ccgatccacc agcacctgga cacggcccgc cttgggcgtg aacttcaccg
    22801 cgttggacag caggttccag accacctgct gcagccgggt gggatccccc atgacggtcg
    22861 cgacggagtc gagcacgggc tgcaggagga tgcccttggc caccgcggcc gggcggatgg
    22921 actcgagcgc ggcttccacc accgagctga gatcgacgga ctcgacctcc aggaccagct
    22981 tgccggacat gatgcggctg atgtccagca ggtcctccac gagctgggac tgggcgtggg
    23041 cgttgcgctc caccgtctcc agcgcgcgcg tgcgccgctc ctcggggagc tgacccgagc
    23101 ggaggatctg cacccagccc aggatggcgg tgagcggcgt gcgcagctcg tgtgacaccg
    23161 tggcgatgaa gtcgtccttg agccggttgg cgtgctcggc ctcggtgcgc gcggcctgct
    23221 cgcgctccag cagggccacg cgctcgacct ccagcgcctt gcgctcggtg atgtccagca
    23281 ccgtgcccgt gaagcgcacg ggccgttgca ggccatcgaa gtacacccgg ccccgcgcgt
    23341 ccagc
//
