LOCUS       NZ_CP022098            20891 bp    DNA     circular CON 17-FEB-2024
DEFINITION  Cystobacter fuscus strain DSM 52655 chromosome, complete genome.
ACCESSION   NZ_CP022098
VERSION     NZ_CP022098.1
KEYWORDS    RefSeq.
SOURCE      Cystobacter fuscus
  ORGANISM  Cystobacter fuscus
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Cystobacter.
REFERENCE   1  (bases 1 to 12349744)
  AUTHORS   Rupp,O., Goesmann,A. and Sogaard-Andersen,L.
  TITLE     Sequencing and comparative analysis of myxobacterial genomes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12349744)
  AUTHORS   Bruckskotten,M., Treuner-Lange,A., Rupp,O., Goesmann,A. and
            Sogaard-Andersen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2017) Department of Ecophysiology, Max Planck
            Institute for Terrestrial Microbiology, Karl von Frisch Str. 10,
            Marburg, Hessen 35043, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 09-AUG-2016
            Assembly Method                   :: Celera Assembler v. 8.1
            Expected Final Version            :: yes
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/17/2024 10:04:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,093
            CDSs (total)                      :: 10,016
            Genes (coding)                    :: 9,906
            CDSs (with protein)               :: 9,906
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 26 of 110
            Pseudo Genes (incomplete)         :: 101 of 110
            Pseudo Genes (internal stop)      :: 1 of 110
            Pseudo Genes (multiple problems)  :: 17 of 110
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:24:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7569986
            Orig. end                         :: 7590877
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20891
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="41"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20891
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20891
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10891](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10891)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(503..519)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.32"
                     /tool="antismash"
     gene            1706..3715
                     /locus_tag="CYFUS_RS30510"
     CDS             1706..3715
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="CYFUS_RS30510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_232536905.1"
                     /transl_table=11
                     /translation="MMHRTTPPGLPSDMDIEKMSRASRMDWLSGGGEMGELIRSMDWSA
                     TPLGPVESWPQSLRTTVSLCLSSTFPLLIAWGPERVQIYNDAYRPICGAKHPQSMGQRF
                     NECWASALPAVGAVVDRAQAGTGSYLENLPMILDRYGYLEEAFMTFSFSPIRDESGNVG
                     GLFHPITETTDKMLSSRRTQALQHLAARLGDVKSLAEVGERLSQAAGESVLDLPFLLYY
                     QFDEAGRHARLLGGTGLAPDSVARPAELDLGGPDEPCWPLARVLESRRMERVEDLRSRF
                     GAWICEPYEEPPHQALLIPLLPVGAASPTGCLVAGISVRRALDASYRAFYELLGNTVTT
                     ALTNVRAHEEEQKRAAALAEIDRAKTAFFSNVSHEFRTPLTLMLGPLEDSLADLQEPLS
                     DGQRQRQQLIHRNGLRLLKLVNSLLDFSRIEAGRVQASYRPTDLSQLTVDLASAFESAM
                     AQAGLTYTVTAPSLPEPVYVDTDFWEKIVLNLISNAFKFTLKGGVDVQLTPREGRVRLT
                     VRDTGTGIPEAEMPRLFERFHRVETTRGRTYEGTGIGLALVQELVRLQGGSLRAESVEG
                     QGSAFHVELPFGHAHLDPSRVDPRDKPLGSQSLSAAFAEEALRWLPDAVEGPPAPAPVT
                     PQEPVSPSCSSSSSSASSATICAVPSRPSSCRRN"
     gene            3634..4308
                     /locus_tag="CYFUS_RS53135"
     CDS             3634..4308
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="CYFUS_RS53135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_095988425.1"
                     /transl_table=11
                     /translation="MLEQQLIGIVSHDLRSPISAIVMSTQLMLRRMDLDEKTAKMAARI
                     QTSAERANRMIRDLLDFTQARLGGGLRIERAPTALHDIVWHAVEEVKLAHSEREFLLDM
                     DEMPTGEWDADRLSQVVINLVTNAVKYSPVPSPVHIQVRKRTHQALIEVHNGGEPISPA
                     LLPLLFEPLQRGGQSVDKAGRSIGLGLYIVEQIVRAHGGTVSVQSTIQSGTTFSVHLPL
                     QV"
     gene            4362..5948
                     /locus_tag="CYFUS_RS30520"
                     /old_locus_tag="CYFUS_006037"
     CDS             4362..5948
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS30520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_006037"
                     /product="hypothetical protein"
                     /protein_id="WP_095988426.1"
                     /transl_table=11
                     /translation="MAHSPLRQAVPASALVSLLALACNNPPPVTIPDPPQVTVRLEETS
                     TVGRGFKLSISTSGCDQVQRLELFNDTTRIKQVPYGGNPTPVELARDEISYAQGLAVPL
                     SLSARVTCADGRTNVSQGQVATFFPVEEVVEPATANTQVVPDYFVVDGSGNSVSFIGCA
                     MDGTRPFLYRVDKSNPSSAQRVEINFPCDATTLITDRKPAGTGTRWVWTPGRGLLSLDA
                     SFKVIYSTNAAVENLVVAADGNAFIYNVTGLYLVTPQGQVRWSREYTGAANPLPGRPAG
                     DPVHITSGTQAGRVLVPLREEHTETVNLRVVVLDYATTDPNGKQLAQYEIDELNPIQAA
                     WTAFNDTGTVMYLGTQQQGSATVRACALGQTKPCQSTYPQSRLWISDPIPGALAALIPY
                     ANNNRLAVITSNRFWFMDVKRNSPTESRIINKDQQALTPTGALVGRFAQPGKDDAFFMF
                     NSAPGTSDVPNPYPVEIVATDAAEQGLLYRYQIPGGLSLYGALDDAGTLWMRAGRKLVK
                     PYSLTEYRQLR"
     gene            complement(5956..6657)
                     /locus_tag="CYFUS_RS30525"
                     /old_locus_tag="CYFUS_006038"
     CDS             complement(5956..6657)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002637807.1"
                     /locus_tag="CYFUS_RS30525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_006038"
                     /product="hypothetical protein"
                     /protein_id="WP_095988427.1"
                     /transl_table=11
                     /translation="MKARVLIALSPVLLSLPVLAAEPVRADLDGDGKPESITVKWDVDQ
                     GGFTLQVGSASVRAKTEDPNEGGVEVVDLDRGDKWKDIAITTGQTDSDHRVFLYGFDGK
                     TLKPLGEVHALTEAKGNGIILSDSWMGFWNKREKYVLDRPAWKIRAVPQPLYAVGVECK
                     VKQSFPIVQGRSDKTPVATLAQDSRIQVLAADTSGRPGEEFYLVKSSTGLLGWASRADL
                     EGKTEGLPFAG"
     gene            6728..7492
                     /locus_tag="CYFUS_RS30530"
                     /old_locus_tag="CYFUS_006039"
     CDS             6728..7492
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS30530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_006039"
                     /product="hypothetical protein"
                     /protein_id="WP_157758763.1"
                     /transl_table=11
                     /translation="MTRLMGMERLRSTPSTATSEDVPSLPSALEVPDNRRQAVPLLDRL
                     NALRSEGVTPDEVASFLDGLVRPLGPEESPRSRADLLLKVLEDERLCTLTTSDGRQVGG
                     AALEALQELGFPFALEVTPTMLARVREHQAAARPMTGIPGGLGAAVASAALVWAVYLPT
                     VPAEYKIWLSVLLLGPVAISALARWGDLPSLHRIANLAQWLVGLACLLAAFNTEKVSTT
                     LTLGFAGVLAHLSAWLLRNGPSKGPPPPEPER"
     gene            complement(7510..8250)
                     /locus_tag="CYFUS_RS30535"
                     /old_locus_tag="CYFUS_006040"
     CDS             complement(7510..8250)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013941204.1"
                     /locus_tag="CYFUS_RS30535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_006040"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_095988429.1"
                     /transl_table=11
                     /translation="MKPRKERLDVLVVERGLAESRTKAQALILAGQVVVGDQRVDKPGS
                     LVPVEAELRLKGEVLPYVSRGGLKLKAAIDRFGLDMRGRVAADIGASTGGFTDCLLQEG
                     AVRVHAIDVGYGQLHEKLRTDPRIRSRERVNARYLTAEDLPEPVDVVVIDVSFISLTQV
                     LPAVLPFLKPKGLLVALVKPQFEVGPDRVGKGGVVRDVAARQEAIDSTVAFVQRQGLTV
                     RGVMDSTVPGPAGNVEALLVADRP"
     gene            complement(8247..10004)
                     /locus_tag="CYFUS_RS30540"
                     /old_locus_tag="CYFUS_006041"
     CDS             complement(8247..10004)
                     /EC_number="2.2.1.7"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624359.1"
                     /locus_tag="CYFUS_RS30540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_006041"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_095988430.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 6.7e-81,
                     bitscore: 270.6, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTERLLPRIHEPKDLRALPESDLPRLCEELREDIIALCGRVGGHL
                     GASLGAVELIVALHRVFHSPQDALVFDVGHQAYAHKLLTGRRERMDTLRQAGGIAPFLD
                     PRESPHDALAAGHASTAVSAALGMLQGRRLRGLPGHAVAVVGDGALTGGLTFEGLNNAG
                     GSHLPLVVVLNDNQMSISANVGAIPALLRTSGARAFFEGLGFTYLGPLDGHDLPTLLHA
                     LREARTSSRPVVVHVLTRKGRGFPPAEADLQTRGHAMGPYEWRDGKLVRSRGGQRTFSE
                     AFASAVEELMVRDARVVTVTPAMLEGSALVRLQQRFPERVFDVGIAESHAVTFCAGLAA
                     TGLRPVCAIYSTFLQRAYDQIIHDVCLPGLPVLFAVDRAGLVGADGATHQGTYDVASLR
                     PIPGLTLMAPVTGGDVPELLATALALPGPSLMRFPRGTLPEWPAGLTPEPLGTGRGARW
                     LKRARAPRVCLLTLGPLALSALEAAAAEPDWSVVDARFVTPLDEAAVLEAAACGRLVVA
                     EEGTTHGGLGSAVLEVLAARRVKARVTLLGMPDVFVPHGDARVQRAHLGLDAAGLRRAA
                     QALLEEEAP"
     gene            complement(10001..10891)
                     /locus_tag="CYFUS_RS30545"
                     /old_locus_tag="CYFUS_006042"
     CDS             complement(10001..10891)
                     /EC_number="2.5.1.10"
                     /GO_function="GO:0004337 - geranyltranstransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011554636.1"
                     /locus_tag="CYFUS_RS30545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_006042"
                     /product="farnesyl diphosphate synthase"
                     /protein_id="WP_095988431.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-58, bitscore:
                     197.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSFDLDAYLNTQQQRVEALLRSRTEELGTHVPPRLLESIRYSLL
                     AGGKRLRPVLCLSFAEAVLQQSTVSRVVEDCACALEFIHTYSLVHDDLPSMDDDDLRRG
                     VPTNHKVYGEAMAILAGDSLLTDAFALVAGGPEPMRAALCRELAVAAGSSGMVGGQVLD
                     IAEDRPAHIDYLTRMHRLKTGALIRAACRMGVIAAGGSADALARADAYGDAVGLAFQIA
                     DDVLDVTSDASTLGKPVGADAAAGRHTFPAVLGLEESKQLAARKVADAIAAVAPLEPRS
                     GPLAALARYSVERSS"
     gene            complement(10893..11282)
                     /locus_tag="CYFUS_RS30550"
                     /old_locus_tag="CYFUS_006043"
     CDS             complement(10893..11282)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624357.1"
                     /locus_tag="CYFUS_RS30550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_006043"
                     /product="response regulator"
                     /protein_id="WP_095988432.1"
                     /transl_table=11
                     /translation="MSKPKVTIVDDDRDTRELLSLALESEDFEVNAAANGLRLIASLQL
                     KRPDVILMDVNMSWIDGFELCKAVKKNEQFRDIPIIFISGRGEPEDKRRGAEAGAADYF
                     VKPLDLEALIRRLRQLLPQPTPEVT"
     gene            complement(11321..11671)
                     /gene="xseB"
                     /locus_tag="CYFUS_RS30555"
                     /old_locus_tag="CYFUS_006044"
     CDS             complement(11321..11671)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624356.1"
                     /locus_tag="CYFUS_RS30555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_006044"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_095988433.1"
                     /transl_table=11
                     /translation="MAKDSRGKAAEAVPEQYGDVVQKLEEMVARLEGGTLSLEESLKSF
                     EEGIKLVRRGEQLLNAAEKRIEELLSADGQDEVVALQAGVKPPVPATPAPARSSPAASR
                     AATPPPEDDVPF"
     gene            complement(11756..13495)
                     /gene="xseA"
                     /locus_tag="CYFUS_RS30560"
                     /old_locus_tag="CYFUS_006045"
     CDS             complement(11756..13495)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002636709.1"
                     /locus_tag="CYFUS_RS30560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_006045"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_095988434.1"
                     /transl_table=11
                     /translation="MKKRRATGEAPPAPPAGQGDLFGGALLPLAPPAVEVVAPKPPEPP
                     ARPPAPVPPAALADVSTSLSPLPGAPARPAAPTRTVLTVGELTQQIKTTLESRFPRVLV
                     RGEVSGFRGANARGHLYFTLKDAEASIDVKMWASQAARLRFHLRDGLAVVVEGSVDLYA
                     PSGRYSLIAFKLEPEGEGALALAFEQLKARLAAEGLIGDNRVRPPRPLPFLPRRIGVVT
                     SRTGAALQDFLRVLHSRHPRLSVLLCDARVQGEGSAEEVARGIERLSRTDVDVIVVTRG
                     GGSKEDLWTFNEERVARAIFASPVPVVSAIGHEIDFTIADFVADWRAPTPSAAAERLAP
                     VLQELEYGLATWSVRLRKAVERRVLELRGALGQARGGLVDPRRRLSNERLRLADAEEAM
                     TRQMRLVLRRHREDLRAHTEHLQRQRPQSRLAEQRARLVQLSARLKDALRADVAARRAR
                     AAQARLRLERVSPVARVAELRARLAEHKARLVALEKDALAHAQRHFQGLEGRLDALSPL
                     KVMSRGYAVTVRRRDGGVVRSIADVQPGELLGIKFASAGARTLQGCEEIEATVTAVKGP
                     VDC"
     gene            complement(13492..15318)
                     /locus_tag="CYFUS_RS30565"
                     /old_locus_tag="CYFUS_006046"
     CDS             complement(13492..15318)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015350641.1"
                     /locus_tag="CYFUS_RS30565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_006046"
                     /product="FHA domain-containing protein"
                     /protein_id="WP_232536906.1"
                     /transl_table=11
                     /translation="MSNGSPPTRRRPTTSSSSDAPSGGAARPRPGARRSPTAAAAPRAP
                     EREPLPPSATKLVCTAGPCAGQEFGLEDGEYVIGRANDNPICIPDSSVSRRHVLIRRLG
                     GGWTVNDLGSGNGTLMNGEPLSEETPLSSGAVLTLGDTELTFNDASNATMMMPMPSAPP
                     ARPARTRTAAAPAAPAAEEEGEEGNGEAAIAPRRPPPRPESRVRPGRGRAAAADPEAQK
                     RKKRLLVISASVFVLLAVVLLVMKVQQQRQAETLRQSAQAAQLQREQIAGLFQEAKNLI
                     RDGKWTDAKARLLELKEAEPDHPQVGDYLARVEKEIPNQLALEAARTALAQNQLGPAFT
                     SLAKVSQDTQMFEVVGSLRRELKDKADKRVGEAQSLLTQKQLDQAKAITDDVLVAFPEH
                     RDAKVVNEQAARAIAERDAPPPPPTPKAVPKPWDQAVDRYRDGDLQGAMAIANDCASKA
                     PQCKTLTSQLGDFGMLYKRMEDLDDRGLTRLLELDRKITSGRGSKLVAGAGKRAANNYY
                     KMASSAKVSGQWGRAMDYAQRALQADPSNTGAANIVNEMRQKAKDVYMSAYAMKDTDPE
                     EALPKFREVMSMTSPDDETHQKAKGWVEKLKR"
     gene            complement(15357..15500)
                     /locus_tag="CYFUS_RS51075"
                     /old_locus_tag="CYFUS_006047"
     CDS             complement(15357..15500)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS51075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_006047"
                     /product="hypothetical protein"
                     /protein_id="WP_157758764.1"
                     /transl_table=11
                     /translation="MGLDFQRDIQFKATERAAPVPGEINRSFPPGAHRCHNRPQKAIEH
                     GP"
     gene            complement(15634..16524)
                     /locus_tag="CYFUS_RS30570"
                     /old_locus_tag="CYFUS_006048"
     CDS             complement(15634..16524)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624352.1"
                     /locus_tag="CYFUS_RS30570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_006048"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_095988436.1"
                     /transl_table=11
                     /translation="MSDVLTTTLMGGSALMFAASVGFFGFGVYQNYFSQFVSEVRDESA
                     GGVAGFSSVAIRKLGVLNRRFMWPGYETKMRRALIRAGEPQAFKPEDIMALQEISAAVG
                     LVAGLILVNAIGENLAWALLFLLFGMYYPLIWVNDQVKKRHLLISRALPYNLDLLTLSV
                     EAGLDFTGALAKVVEKGKAGPLREELQIVLKQLKMGKTREEGLKAMIARVDLPSLTTFV
                     TALIQADKMGTSLGKVLRIQSTQLRIDRTQRAEKLAGEAPVKMLFPLIACIFPTVFMVL
                     FGPIVFQFMFGDVGS"
     gene            complement(16534..17379)
                     /locus_tag="CYFUS_RS30575"
                     /old_locus_tag="CYFUS_006049"
     CDS             complement(16534..17379)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015350644.1"
                     /locus_tag="CYFUS_RS30575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_006049"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_002624351.1"
                     /transl_table=11
                     /translation="MLAGIVLLLVTGSVFFFSLVIFTVLAKAYEQYQERYVVKSMNDLS
                     DMFLFIDARQLLVLNIASMCLLGILSYIIFNPILCVVCTIFGFFLPIILVKHYRKRRIK
                     KFNVQLVDALQAMANAFKAGLTFPQAIEHVAREAQPPLAQEFGLFVKEIKLGVPLEEAL
                     INMGRRVGSDDLELVVVATNIARQLGGNMAEMFETISSVIRERFRLEGKIDALTSQGKL
                     QGWVVAAMPGVLGLVLNYMRPDLMEPMMDHWFGYVLVTIIALMEVMGVLIIRRIVNIDI
                     "
     gene            complement(17445..18269)
                     /gene="cpaB"
                     /locus_tag="CYFUS_RS30580"
                     /old_locus_tag="CYFUS_006050"
     CDS             complement(17445..18269)
                     /codon_start=1
                     /gene="cpaB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624350.1"
                     /locus_tag="CYFUS_RS30580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_006050"
                     /product="Flp pilus assembly protein CpaB"
                     /protein_id="WP_095988437.1"
                     /transl_table=11
                     /translation="MLKGKTPLIIALGLGLLAGIIAWSAIKKKEADVRRGWNLVPVVVA
                     TQDLPEGTVITFEMISQRQVPEQFVTSSVVKPDSANYVVGQKVLVALQTGDPLLWSQFE
                     TTKAAERLSTKVQKKVRAVTIDSRVTTSVGGWVRPNDHVDVIGTFRDPQTDESVAVTLL
                     QNVIVLATGKVTGTTNVNLIPESQREYNNITLMVIPEEAEILTLAAELGNLTLSLRNEE
                     DVDMIEERGRATITTLLSGERTRVLEQKRREIIQIIKGSASEKSAVGSSGTP"
     misc_feature    complement(18368..18386)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 21.56"
                     /tool="antismash"
     misc_feature    18391..18404
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.08"
                     /tool="antismash"
     gene            18551..19564
                     /locus_tag="CYFUS_RS30585"
                     /old_locus_tag="CYFUS_006051"
     CDS             18551..19564
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624349.1"
                     /locus_tag="CYFUS_RS30585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_006051"
                     /product="TadE family protein"
                     /protein_id="WP_232536907.1"
                     /transl_table=11
                     /translation="MSQHSPPSRESGQAAVESALVLPLMVFLGLGLIQLTMMQQAKLMT
                     EYAAYCAARTGIVWNGNNERMHDAAIIALLPTMGRTDTLLHLGKTWALAQLYDEALQLL
                     AWPNKKQSDDPKAGSTKTSSVPASVNGSNLFGQVRVDTVNPSWYSPIKSVWKLRSGAGW
                     KELDFDGPDTYPQVPSLESKIAKFFNLALPDNDEEVYRKATVLSIRVRYWYELRVPFAN
                     WIIFTSWWAANAGVTLGGAIYKPTTDSGARITSKKGGMSEVGAVPVKGLEHQRGYNSLY
                     QPEMTVLWMLATGSIPLLSKYVGKRYFIPLTATYSMRMQSNFYYKWLMHLEPEWGL"
     misc_feature    19673..19687
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
     misc_feature    19999..20013
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.05"
                     /tool="antismash"
ORIGIN
        1 caccacctgc cccgcgttct tcgcgtggtg gatggcgttg gtgatgaggt tctgcaacac
       61 ctcgtgcagc ttgagctcgt cgccgatgag catcatgcgc tcgggcgcct cggcccgcag
      121 ggcgacgccc cgctccttgg agaggattcc cagctcgctc acgctctcgc ggcagagcac
      181 cgagatgtcc agcacgcgcg gctcgatgga caggcgcgcc acgtccccct tgccccgctc
      241 cagcagcgac tccaccagcc cgaggatctt ccggccctgg cggatcatcg cctcggcgga
      301 ctgcttctgc atctcgtcca gctcgccctc gagcaagagc cgcccatgcc ccagcagcac
      361 ctgcaacgga gcgcgcaggt catggctgca caccgcgatg atctcgtcct tgagtcggtt
      421 caggtccttg agccggcggt tggcgtccga cagctcgcgg tagcgctcca cgtaggcgag
      481 ctccagctcg tcgcgcttct tcttgaggct ggtgtgcagg cgcgcgttgc ggatgcagtt
      541 ggcgagcgcc gcgcccaccg cctgggcgaa ctcctgctcg tcgcggttga agccctcggt
      601 gccgtgggag atgcgcagga agagcgcccc gagcagctcg tcctggcaca ccagcggctg
      661 cacgaggatg gagcgcacgc cgagcgacgc catggcggga tgcacctcgg ccatgagtgg
      721 atcccgctgc gcctcctcca ccaacacctg ctgccgcgtc tccagcgccc gacgcagctc
      781 ggggtagcgc gccaggtcca cgtccagcga caggcccggg tcctccatgg tggccaccac
      841 gctcgcggtg cgcgagttgc tgtcctccac cagcaccacc gagcagcggt ccgcgttgat
      901 gaccgccccc accttctcca ccaccaggcg caggatgtcc tccagctcca gcgagctggt
      961 ggccacctgg gtgatctcca gcagccgctc catgcggttg cgcgtgcgcg ccatgagccg
     1021 ccgctcgcgc aaggccgtgt ccagccgcgt ggtgagctcc tccaggttgc gcacccagtc
     1081 atccgcgggc agcttgcgca gcacctccga gcgcgtccgg gtgagatccg ccagcacccg
     1141 cagctcgcgc agccgggcat cctggcggat ggcctcgagc gcctcggtgg cgcgcttgcc
     1201 cgtggcggac acgagcaccg catccggccg cgacgactcg gccaggcgcg gcaactcgtc
     1261 caggtcctcg gtgatgaccc actggaagcc cgcatgcgac agatgcgcga gcaggacctc
     1321 gttggtctta cgtgctccaa tcaccaggac gcggccacga ggccccgcca gttccgctct
     1381 caaggaatcc cccatggttc ctggtccttt cctaaggggt gaaaagacca gcgattttcc
     1441 aacttggcgt cagccgtcat gcgcggctcc aaatcatgcc gtcgaagcgc gtggggggcc
     1501 agcgtggcga accgcgcgag tcagggcaag cgtcatgatt caactccccc acgtaggaac
     1561 cccaccggcc ccaggacaaa gcgcttcctt tctcgtctgc cctgaatcca acacatgggg
     1621 agggctgctt cctccctacc cgatgggatc cctcccctcc ccggcagccg agcccctggg
     1681 cccggtccag agcgagtaga cccgtatgat gcaccgcacg acgccccccg gcctcccgtc
     1741 ggacatggac atcgagaaga tgtcgcgagc ctcccgcatg gattggctgt cgggcggtgg
     1801 ggagatgggc gagctcatcc gatccatgga ttggtccgcc acgcccctgg gtcccgtcga
     1861 gtcctggccc cagagcttgc gcaccaccgt cagcctctgc ctgtcctcca ccttccccct
     1921 cctgatcgcc tggggacccg agcgcgtgca gatctacaac gacgcctacc gccccatctg
     1981 cggcgccaaa cacccccaat ccatggggca gcgcttcaac gagtgctggg cctcggcgct
     2041 tcccgccgtc ggggccgtgg tcgaccgggc ccaggcgggc accggctcgt acctcgagaa
     2101 cctgcccatg atcctcgacc ggtacggcta cctggaggag gcattcatga ccttctcctt
     2161 cagccccatc cgcgacgagt cgggaaacgt cggcggcctc ttccacccca tcaccgagac
     2221 caccgacaag atgctcagct cccggaggac ccaggcgctg caacacctcg ccgcgcggct
     2281 cggcgacgtg aagtccctgg ccgaggtggg cgagcggctg agccaggccg ccggggagtc
     2341 cgtgctcgat ctgcccttcc tgctctacta ccagttcgac gaggcgggcc ggcatgcccg
     2401 gctgctcgga ggcaccgggc tcgcgccgga cagcgtggcc cggccggccg agctcgatct
     2461 cgggggcccg gacgagccgt gctggccgct ggcccgggtg ctggaatcgc ggcggatgga
     2521 gcgggtggag gatctgcgga gccggttcgg cgcctggatc tgcgagccct acgaggagcc
     2581 tccccatcag gcactgctca ttcccctgct gccggtgggc gcggcctccc ccaccgggtg
     2641 cctggtggcg ggcatcagcg tgcggcgcgc cctggacgcg agctaccgcg ccttctacga
     2701 gctgctgggc aacaccgtga cgaccgccct caccaacgtc cgggcgcacg aggaggagca
     2761 gaagcgcgcc gcggccctcg ccgagatcga tcgcgccaag acggccttct tctccaacgt
     2821 gtcccacgag ttccgcacgc ccctgaccct gatgctgggg ccgctggagg actcgctggc
     2881 ggatctccag gagccgctgt ccgacgggca gcgccagcgg cagcagctca tccaccgcaa
     2941 cggcctgcgg ctgctcaagc tcgtcaactc cctgctggac ttctcccgca tcgaggcggg
     3001 ccgggtccag gccagctacc ggcccaccga cctgtcccag ctcaccgtgg acctggcgag
     3061 cgccttcgag tcggcgatgg cccaggcggg actcacgtac accgtcacgg cgccctccct
     3121 ccccgagccc gtctacgtgg acaccgactt ctgggagaag atcgtcctca acctcatctc
     3181 caacgccttc aagttcaccc tgaagggcgg cgtcgacgtc cagctcaccc cgcgcgaggg
     3241 ccgggtacgg ttgacggtgc gggataccgg aaccggcatt cccgaggccg agatgcctcg
     3301 tctgttcgag cgcttccacc gcgtggagac cacccggggc cgcacctacg agggcacggg
     3361 catcggactg gcgctggtgc aggagctggt gaggttgcag ggcggctcgc tccgcgcgga
     3421 gagcgtggag ggacagggca gcgcgttcca tgtcgagctg cccttcggcc atgcccacct
     3481 ggatccctcg cgcgtcgatc cgcgcgacaa acccctgggc tcgcaatcct tgagcgcggc
     3541 cttcgccgag gaggcgctgc gctggttgcc cgatgcggtg gaaggccccc ctgccccggc
     3601 gcccgtcacc ccgcaagagc ccgtctcccc gtcgtgctcg agcagcagct catcggcatc
     3661 gtcagccacg atctgcgcag tcccatctcg gccatcgtca tgtcgacgca actgatgctg
     3721 cgccgcatgg acctggacga gaagacggcg aagatggccg cgcgcatcca gaccagcgcg
     3781 gagcgtgcca accggatgat ccgcgacctg ctcgacttca cccaggcccg gctgggcggg
     3841 ggtctgcgca tcgagcgcgc gcccacggcg ctgcatgaca tcgtctggca cgccgtggag
     3901 gaggtgaagc tcgcgcattc cgagcgcgag ttcctcctcg acatggacga gatgcccacc
     3961 ggcgagtggg acgcggatcg gctctcccag gtggtgatca acctcgtgac caacgcggtg
     4021 aagtacagcc ccgtgcccag ccccgtgcac atccaggtcc gcaagcggac ccaccaggcc
     4081 ttgatcgagg tgcacaacgg cggcgagccc atctccccgg ccctgctccc cctgctcttc
     4141 gagcccttgc agcgcggcgg gcagagcgtg gacaaggcgg gccggagcat cggcctgggg
     4201 ctctacatcg tggagcagat cgtccgcgcg catggcggta cggtcagcgt ccaatcgacc
     4261 atccagagtg gcacgacctt ctcggtccac ctgcccctcc aggtttgacg cggtccggcc
     4321 tgacaggagc cggtcctcct gacctagagt gcgcccccat catggcccac tcccctctcc
     4381 gtcaggcagt gcccgcctcg gcgctggtgt ccttgttggc gctcgcgtgc aacaaccccc
     4441 cgcccgtcac catcccggac cccccccagg tcaccgtgcg cctggaggag acgagcaccg
     4501 tgggacgcgg cttcaagctc tccatctcca cctccgggtg cgatcaggtg cagcggctgg
     4561 agctgttcaa cgacaccacg cgcatcaagc aggtgcccta cggcggcaat cccaccccgg
     4621 tggagctggc tcgcgacgag atcagctacg cgcagggcct cgcggtgccc ctgtccctga
     4681 gcgcccgcgt cacctgcgcc gatggccgca ccaatgtctc ccagggccag gtggccacct
     4741 tcttccccgt ggaggaggtg gtggagccgg ccacggccaa cacccaggtg gtgccggact
     4801 acttcgtcgt cgacggcagc ggcaactccg tgtcgttcat cggctgcgcg atggatggca
     4861 cccgcccgtt cctctaccgg gtggacaaga gcaacccgag ttccgcccag cgcgtggaga
     4921 tcaacttccc ctgtgacgcg accacgctca tcaccgaccg caagccagcc ggcacgggca
     4981 cccgctgggt ctggacgccg ggccggggcc tgctctccct cgacgcgagc ttcaaggtca
     5041 tctactcgac caacgccgcc gtggaaaacc tcgtggtggc cgccgacggc aatgccttca
     5101 tctacaacgt cacgggcctc tatctggtca cgccccaggg gcaggtgcgc tggagccggg
     5161 agtacaccgg agcggcgaac cctcttcccg gccggcccgc gggagatccc gtccacatca
     5221 ccagtgggac ccaggcgggc cgggtcctgg tgcccctgcg cgaggagcac accgagaccg
     5281 tcaacctccg cgtggtggtc ctggactacg ccaccaccga ccccaacggg aagcagctcg
     5341 cccagtacga gatcgatgaa ctcaatccca tccaggcggc ctggacggcg ttcaacgaca
     5401 ccggcacggt gatgtacctg ggcacgcagc aacaaggttc ggcgaccgtc cgcgcctgcg
     5461 ccctcgggca gaccaagccc tgccagtcca cgtatcccca gtcccggctg tggatcagcg
     5521 atccgattcc gggcgccctc gccgcgctga ttccgtacgc caacaacaac cgcctggcgg
     5581 tcatcacctc caaccgcttc tggttcatgg acgtgaagcg caactcgccc accgagagcc
     5641 ggatcatcaa caaggatcag caggccctca cgcccaccgg cgcgctggtg ggacgcttcg
     5701 cccagcccgg caaggacgac gcgttcttca tgttcaacag cgcgcccggc acgagcgatg
     5761 tccccaaccc ctacccggtg gagatcgtcg ccacggacgc ggccgagcag ggcctgctct
     5821 accgctatca aatcccaggc ggcctgagcc tctacggggc cctggacgac gccggcacgc
     5881 tctggatgcg cgcgggccgc aagctggtga agccctactc tctgaccgag taccggcagt
     5941 tgcgttgagc ggcgctcacc ccgcgaaggg cagaccctcg gtcttgccct cgaggtccgc
     6001 cctcgaggcc caccccaaca gcccggtgga ggacttcacg aggtagaact cctcgcccgg
     6061 gcgccccgag gtgtccgcgg cgagcacctg gatgcgtgag tcctgcgcca gggtggccac
     6121 cggcgtcttg tcgctccggc cctggacgat ggggaaggac tgcttcacct tgcactcgac
     6181 gcccacggcg tagaggggct ggggcaccgc gcggatcttc cacgccgggc gatccaggac
     6241 gtacttctcc cgcttgttcc agaagcccat ccaggagtcc gagaggatga tgccattgcc
     6301 cttggcctcg gtcagggcgt ggacctcgcc caggggcttg agcgtcttgc catcgaagcc
     6361 atagaggaag acacggtggt cgctgtccgt ctggcccgtg gtgatggcga tgtccttcca
     6421 cttgtcgccg cggtccaggt ccacgacctc cactccaccc tcgttgggat cctcggtctt
     6481 cgcccggacg ctggcgcttc ccacctggag ggtgaagccc ccctgatcca cgtcccactt
     6541 cacggtgatg gactccggct tgccatcccc atcgaggtcc gcgcgcacgg gctcggcggc
     6601 cagcaccgga agagacagca acacgggaga cagggcgatc aggactcgag ccttcatgga
     6661 agcgacctcg gggaaaaggg gcggacatcc taccggcccg gcgcctgttt ccacgggagc
     6721 ccgggtgatg actagactga tgggcatgga acgcctccgc tccaccccgt ccaccgccac
     6781 ctccgaggac gttccgtccc tcccctccgc cttggaggtg ccggacaaca gacgccaggc
     6841 cgttccgcta ctcgatcggc tgaacgccct gcgctcggag ggcgtcacgc cggacgaggt
     6901 ggcgtccttc ctggacggac tcgtgaggcc cctgggcccg gaggagtccc cgcggagccg
     6961 cgcggacctc ctgttgaagg tgctggagga cgagcggctg tgcaccctga ccacctccga
     7021 tgggcgacag gtgggcggcg cggccctgga ggccttgcag gagctgggct ttcccttcgc
     7081 gctcgaggtg acccccacca tgctcgcccg ggtccgcgag catcaggccg ccgccaggcc
     7141 catgaccggc atcccgggcg ggctgggcgc ggccgtggcc agcgccgcgt tggtctgggc
     7201 ggtgtacctg cccaccgtcc cagcggagta caagatctgg ctctccgtgc tgctgctcgg
     7261 acccgtggcg atatcggccc tcgccaggtg gggcgacctt ccgtcgctcc atcgcatcgc
     7321 caacctcgct cagtggctgg tgggcctggc gtgtctgctc gcggccttca acacggagaa
     7381 ggtctccacg accctcaccc tgggcttcgc cggagtcctg gcgcacctct ccgcctggct
     7441 cctgcgcaac ggcccttcga aggggccgcc tccgccggag cccgagcgct gaacccccac
     7501 gccgccggct cagggccggt ccgcgacgag cagcgcctcg acgttgcccg cggggcccgg
     7561 cacggtggag tccatcaccc cgcgcaccgt gaggccctgc cgctggacga aggcgaccgt
     7621 ggagtcgatg gcctcctggc gcgcggccac gtcccgcacc acgccgccct tgcccacccg
     7681 atccggcccc acctcgaact ggggcttcac gagcgccacc aacaggccct tgggcttgag
     7741 gaagggcagc accgcgggca gcacctgcgt gagcgagatg aagctcacgt cgatgaccac
     7801 cacgtccacc ggctcgggca gatcctcggc ggtgaggtag cgggcgttga cgcgctcgcg
     7861 cgagcggatg cgcggatccg tgcgcagctt ctcgtggagc tgcccatagc ccacgtcgat
     7921 ggcatgcacg cgcacggccc cctcttgcag gaggcagtcg gtgaagccgc ccgtgctggc
     7981 gccgatgtcc gccgccaccc ggccgcgcat gtccaggccg aagcgatcga tggcggcctt
     8041 gagcttcaac ccaccccgcg acacgtaggg caacacctcg cccttgagtc gcagttccgc
     8101 ctccacgggc accagcgagc cgggcttgtc cacgcgttga tcgccgacga ccacctggcc
     8161 ggcgaggatg agggcctggg ccttggtccg cgactccgcg agcccccgct ccaccaccaa
     8221 cacgtccagc cgctccttgc gcggcttcat ggtgcttcct cctcgagcaa cgcctgggcc
     8281 gcgcgtcgca accccgcggc atcaaggccc aggtgcgccc gctgcacgcg cgcatctcca
     8341 tgggggacga agacatccgg catgccgagc agcgtcaccc gggccttcac gcgccgggcg
     8401 gcgagcacct ccaacaccgc gctgcccagg cctccgtgcg tcgtgccctc ctccgccacc
     8461 accagacgcc cacaggcggc ggcttccagc acggccgcct cgtcgagcgg ggtgacgaag
     8521 cgcgcgtcca ccacgctcca gtccggctcc gccgcggcgg cctccagcgc ggacagggcg
     8581 agtggcccca gggtgagcag gcacacgcgc ggagcccgcg cccgcttcaa ccagcgcgcg
     8641 ccccgtcccg tccccagcgg ctcgggcgtg agtccggccg gccactccgg caaggtgccc
     8701 cggggaaagc gcatcagcga ggggcccggc agcgcgagcg cggtggcgag caactccggc
     8761 acgtccccac ccgtcaccgg tgccatgagc gtgaggccgg gaatgggccg cagcgaggcc
     8821 acgtcgtagg tgccctggtg cgtggcgcca tccgccccca cgaggcccgc gcgatccacg
     8881 gcgaagagca cgggcaggcc cggcaggcag acgtcgtgga tgatctgatc gtacgcgcgc
     8941 tgcaggaacg tcgagtagat ggcgcacacg ggccgcagtc ccgtggcggc caggcccgcg
     9001 cagaaggtga cggcgtgaga ctcggcgatg cccacgtcga agacgcgctc ggggaagcgc
     9061 tgctggagcc gcaccagggc gctgccttcc agcatggccg gcgtcaccgt caccacgcgc
     9121 gcgtctcgca ccatcagctc ttccacggcg gaggcgaagg cctcgctgaa ggtgcgctgg
     9181 cccccgcgcg agcgcacgag cttcccatcc cgccactcgt acgggcccat ggcgtggccg
     9241 cgcgtctgga gatccgcctc ggcgggggga aagccccggc ccttgcgcgt gagcacgtgc
     9301 accaccaccg ggcgcgacga ggtgcgcgcc tcgcgcagcg cgtgcaggag cgtgggcaga
     9361 tcgtgtccgt ccaggggccc caggtaggtg aagccgagcc cctcgaagaa ggcccgggcc
     9421 ccgctcgtgc gcagcagcgc ggggatggcg cccacgttgg cggagatgga catctggttg
     9481 tcgttgagca ccaccaccag cggcaggtgc gagcccccgg cgttgttgag cccctcgaag
     9541 gtgaggcccc cggtgagggc tccgtcaccc accaccgcca ccgcgtgccc gggcagcccg
     9601 cgcagccgcc ggccctggag catgcccagc gcggcggaga cggcggtgct cgcgtggccc
     9661 gcggccaggg catcgtgcgg gctctcgcgg ggatccagga agggcgcgat gcccccggcc
     9721 tggcgcaggg tgtccatgcg ctcgcgccgg ccggtgagca gcttgtgggc gtaggcctgg
     9781 tggcccacgt cgaagacgag cgcgtcctgg ggcgagtgga agacgcggtg cagggcgacg
     9841 atgagctcca ccgcgcccag cgaggcaccc aggtggccgc ccacgcggcc acacagggcg
     9901 atgatgtcct cccgcagctc ctcgcacaga cggggcaggt cggactcggg cagggcccgg
     9961 aggtccttcg gttcgtggat gcgcggcagg agccgctccg tcacgagctg cgctccaccg
    10021 agtagcgcgc gagcgccgcc agcggacccg agcggggctc cagcggggcc acggcggcga
    10081 tggcgtcggc caccttgcgc gccgcgagct gcttggactc ctccaggccc agcaccgccg
    10141 ggaaggtgtg acgtccggcg gcggcgtccg cgcccacggg cttgcccagg gtggacgcgt
    10201 cgctcgtgac gtccagcacg tcatcggcga tctggaaggc gagccccacc gcgtccccgt
    10261 aggcgtccgc gcgggcgagc gcatcggcac tgccacccgc ggcgatgacg cccatgcggc
    10321 acgcggcgcg gatgagggcg cccgtcttca ggcgatgcat ccgggtgagg tagtcgatgt
    10381 gggccggccg atcctcggcg atgtccagca cctggccgcc caccatgccc gaggaacccg
    10441 cggccacggc cagctcgcgg cagagcgcgg cgcgcatcgg ctcggggccg ccggccacca
    10501 gggcgaaggc atccgtgagc agcgagtcgc ccgcgaggat ggccatcgcc tcgccgtaca
    10561 ccttgtggtt ggtgggcacg ccccggcgca gatcgtcgtc gtccatggac ggcaggtcat
    10621 cgtgcacgag cgagtaggtg tggatgaact cgagcgcgca cgcgcagtcc tccaccaccc
    10681 gcgacacggt gctctgctgg agcacggcct cggcgaagct caggcacaac accggacgca
    10741 gccgcttgcc acccgccagc agcgagtagc ggatggactc gagcaggcgg gggggcacat
    10801 gggtccccag ctcctccgtg cgcgagcgca gcagcgcttc cacccgctgc tgctgggtgt
    10861 tcaggtaggc atccagatcg aaagacgaca tgtcaggtga cctcgggcgt gggctgtgga
    10921 aggagctggc gcagacggcg gatcagcgcc tccaggtcca ggggcttcac gaaataatcc
    10981 gcggcgccgg cttccgcgcc gcgccgcttg tcctcgggct ccccacgtcc actgatgaag
    11041 atgatgggga tgtcgcggaa ctgttcgttc ttcttgacgg ccttgcacaa ctcgaagcca
    11101 tcgatccagg acatgttcac gtccatgagg atgacgtcgg gccgcttgag ttggagggag
    11161 gcgatgagcc gcagaccgtt ggcggcggcg ttgacctcga agtcctcgga ctccagggcg
    11221 agcgagagca actcgcgcgt gtcgcggtca tcgtcgacga tggtgacctt gggcttggac
    11281 atgagatggc cggggtgggg ggtcgtcgtc cctggacaaa ctagaacggc acatcatcct
    11341 cgggaggggg ggtggccgct cgggaagcgg ccgggctgct ccgggccgga gcgggagtgg
    11401 cgggcaccgg gggcttcacg cccgcctgca gcgccaccac ctcgtcctgc ccatccgcgg
    11461 acagcagctc ctcgatgcgc ttctccgccg cgttgagcaa ctgctcaccc cggcgcacca
    11521 gcttgatgcc ctcctcgaag gacttgagcg actcctcgag cgagagggtg ccgccctcga
    11581 gccgggccac catctcctcg agcttctgca ccacgtcccc gtactgttcg ggcaccgcct
    11641 ccgccgcctt gcccctgctg tccttcgcca cggtgtgtcc acctcgagag aaagagccgg
    11701 cggactctat agaggaggcc atctccaggt tccagaggga cctgaggggg gttggttagc
    11761 aatccaccgg acccttcacg gccgtcacgg tggcctcgat ttcctcacat ccctggagcg
    11821 tcctggcccc ggcgctggcg aacttgatgc cgagcagctc accgggctgg acgtccgcga
    11881 tggaacgcac cacgcccccg tcgcgccgcc ggacggtgac ggcgtagccg cgggacatga
    11941 ccttgagggg gctcagggca tccagccggc cctccaaccc ctggaagtga cgctgggcgt
    12001 gggcgagcgc gtccttctcc agggccacca ggcgggcctt gtgctcggcc agccgggcgc
    12061 gcagctcggc cacccgcgcc accggggaga cacgctccag ccgcaagcgg gcctgggccg
    12121 cccgggcccg gcgcgccgcc acgtccgcgc gcagcgcgtc cttgagccgg gcggacagct
    12181 gcaccagacg cgcgcgctgc tcggccagcc gcgactgggg ccgctggcgt tgcaggtgct
    12241 cggtgtgggc ccggagatcc tcccggtgcc gccggagcac cagacgcatc tgccgcgtca
    12301 tggcctcctc ggcgtccgcc agccgcagcc gctcgttgga caggcgccgg cggggatcca
    12361 ccagcccgcc ccgcgcctgc cccagggcgc cgcgcaactc caggacgcgg cgctcgaccg
    12421 ccttgcgcag ccgcaccgac caggtggcca ggccgtactc cagctcctgc agcaccggcg
    12481 cgagccgctc cgccgccgcg ctgggcgtgg gcgcgcgcca gtccgccacg aagtccgcga
    12541 tggtgaagtc aatctcgtgc ccgatggcgg acaccaccgg cacgggcgag gcgaagatgg
    12601 cgcgcgccac gcgctcctcg ttgaacgtcc agagatcttc cttcgagccg ccgccgcgcg
    12661 tgacgacgat gacgtccacg tccgtgcgcg acaggcgctc gatgccgcgg gccacctcct
    12721 cggcggaccc ctcgccctgc acgcgcgcgt cacacagcag cacggacagg cgcgggtggc
    12781 gcgagtgcaa cacgcgcagg aagtcctgca gcgccgcgcc ggtgcggctc gtcaccacgc
    12841 cgatgcgccg gggcaggaag ggcagcgggc ggggcggccg gacgcggttg tcgccaatga
    12901 gcccctcggc ggccagccgt gccttgagct gctcgaaggc gagcgccagt gccccctccc
    12961 cttccggctc cagcttgaag gcgatgaggc tgtagcgccc cgagggcgcg tagaggtcca
    13021 cgctgccctc gaccaccacc gcgagcccgt cgcgcaggtg gaagcgcagc cgcgccgcct
    13081 gcgaggccca catcttcacg tcgatcgacg cctccgcgtc cttgagcgtg aagtacaggt
    13141 ggccgcgggc gttggcgccc cggaagccgg acacctcgcc acgcaccagc acccggggga
    13201 agcgcgactc gagggtcgtc ttgatctgct gggtgagctc gcccacggtg agcaccgtgc
    13261 gcgtgggcgc cgccgggcgc gcgggcgctc cgggcagcgg ggacagcgac gtggacacgt
    13321 ccgccagcgc cgcgggcggc acgggtgcgg ggggccgggc gggaggctcg ggcggcttgg
    13381 gcgccacgac ctccaccgcc ggcggagcca ggggaagaag agccccgccg aacagatctc
    13441 cctgtccggc cggaggggcg ggaggagcct cgcccgtcgc gcgccgcttc ttcatcgctt
    13501 gagcttctcg acccagccct tggccttctg gtgcgtctcg tcatccggcg acgtcatgga
    13561 catgacctcg cggaacttgg gcagcgcctc ctcgggatcg gtgtccttca tggcgtaggc
    13621 gctcatgtag acgtccttcg ccttctggcg catctcgttg acgatgttgg cggcgcccgt
    13681 gttgctcggg tcggcctgga gggcgcgctg ggcatagtcc atcgcgcggc cccactgccc
    13741 ggacaccttc gccgacgagg ccatcttgta atagttgttg gcggcgcgct tgccggcccc
    13801 ggcgacgagc ttgctgccgc ggccgctggt gatcttccgg tccagctcca gcaggcgcgt
    13861 caggccccgg tcatccagat cctccatccg cttgtagagc atgccgaagt cgccgagctg
    13921 gctcgtgagc gtcttgcact gcggggcctt ggatgcgcag tcgttggcga tggccatggc
    13981 gccctgcaga tcgccatcgc ggtagcgatc caccgcttga tcccacggct tgggcaccgc
    14041 cttgggagtg ggcggagggg gcggcgcgtc gcgctccgcg atggcgcgcg cggcctgctc
    14101 gttgacgacc ttggcgtcgc ggtgctccgg gaaggccacg agcacgtcgt cggtgatggc
    14161 cttggcctga tccaactgct tctgcgtcag gagcgactgg gcctcgccca cgcgcttgtc
    14221 ggccttgtcc ttcagctccc ggcgcaacga gcccaccacc tcgaacatct gggtgtcctg
    14281 ggacaccttg gccagggagg tgaacgccgg gccgagctgg ttctgcgcca gcgccgtccg
    14341 ggccgcctcg agcgccagct ggttgggaat ctccttctcc acgcgcgcca ggtagtcgcc
    14401 cacctgcggg tggtcgggct cggcctcctt gagctcgagc agccgcgcct tggcgtcggt
    14461 ccacttgccg tcgcggatga ggttcttggc ctcctggaag agaccggcga tctgctcgcg
    14521 ctgcagctgg gcggcctggg cgctctggcg cagggtctcg gcctgccgct gctgctgcac
    14581 cttcatgacg agcagcacga ccgccaggag cacgaagacg gacgcggaga tcaccaacag
    14641 gcgcttcttg cgcttctgcg cctcgggatc cgccgccgcc gcgcggcccc ggcccgggcg
    14701 cacccgcgac tcgggacggg gcggaggacg ccggggggcg atcgccgcct ccccattccc
    14761 ctcctcccct tcctcctccg cggcgggcgc cgccggggcg gccgcggtgc gggtacgtgc
    14821 cgggcgcgcg ggcggtgccg agggcatcgg catcatcatc gtggcattgg aggcgtcgtt
    14881 gaaggtgagc tccgtgtcgc ccagcgtgag cacggcgccg gaactcaggg gcgtctcctc
    14941 gctcaggggc tcgccattca tcagggtgcc gttaccggac cccagatcgt tcaccgtcca
    15001 gcctccgccc aggcgccgga tgagcacgtg ccgacgggac accgaggagt ccgggatgca
    15061 gatggggttg tcgttggcac ggccgatgac gtactcgcca tcctccagac cgaactcctg
    15121 accggcgcag ggacccgcgg tgcacaccag cttcgtggcc gacggcggga ggggctcccg
    15181 ctcgggggca cgaggcgcgg cggcggcggt gggactccta cgcgctccgg gacgcggacg
    15241 cgcggcgccg cccgaggggg cgtccgacga ggaactggtc gtggggcgac gacgggtggg
    15301 aggggaaccg ttcgacatgg gaagtcaccg cttcatttcg tacacggaga cgggcgtcac
    15361 ggcccgtgct cgatggcctt ctggggccga ttgtgacagc gatgcgcccc gggaggaaag
    15421 ctccggttga tttcgccggg caccggggcc gcccgctcgg tggccttgaa ctggatgtcg
    15481 cgctggaaat ccagccccaa gtggccagat gtccgctcca ggtcgaccgt caaccggccg
    15541 ggcatgaggc ggacccccgg gtccaggtcc gacgggccct ggagtgcctc gggggatgct
    15601 cctcgtccgc gcgggaggtc ctccccgcgc ggactagctg ccgacgtcgc cgaacatgaa
    15661 ctggaacacg atgggcccga agagcaccat gaacaccgtg gggaagatgc acgcgatgag
    15721 cgggaagagc atcttcaccg gcgcctcgcc ggcgagcttc tcggcgcgct gggtgcggtc
    15781 gatgcgcagc tgggtggact ggatgcgcag caccttgccg aggctggtgc ccatcttgtc
    15841 cgcctggatg agcgcggtga cgaaggtggt gagcgacggc aggtccacgc gagcgatcat
    15901 cgccttgagg ccctcctcgc gcgtcttgcc catcttgagc tgcttgagga cgatctgcag
    15961 ctcctcgcgc agcgggcccg ccttgccctt ctccaccacc ttggccagcg cgcccgtgaa
    16021 gtccaggccc gcctccaccg acagcgtcag caggtccagg ttgtagggca gcgcccggga
    16081 gatgagcagg tggcgcttct tcacctgatc gttcacccag atgagcgggt agtacatgcc
    16141 gaagagcagg aagagcagcg cccaggccag gttctcgccg atggcgttca ccaggatgag
    16201 ccccgccacc agacccacgg cggcggagat ctcctgcagc gccatgatgt cctcgggctt
    16261 gaaggcctgg ggctcacccg cccggatgag ggcgcggcgc atcttggtct cgtagcccgg
    16321 ccacatgaag cggcggttga gcacgccgag cttgcggatg gcgaccgagc tgaagcccgc
    16381 gacgccaccg gccgactcgt cgcgcacctc cgagacgaac tgcgagaagt agttctggta
    16441 gacgccgaac ccgaagaagc ccacggacgc cgcgaacatc agcgccgagc cgcccatcag
    16501 cgtcgtggtg agaacatcgc tcatggccgt tccttaaatg tcgatgttga cgatgcgccg
    16561 gatgatgagc acgcccatga cttccatgag cgcgatgatc gtcaccagca catacccgaa
    16621 ccagtggtcc atcatcggct ccatcaggtc gggacgcatg tagttgagca ccaggccgag
    16681 cacgcccggc atggccgcca ccacccagcc ctgcagcttg ccctgggagg tgagcgcgtc
    16741 gatcttcccc tcgagccgga agcgctcgcg gatgacgctc gagatggtct cgaacatctc
    16801 cgccatgttg ccgcccagct gccgcgcgat gttggtggcc accaccacca gctccaggtc
    16861 gtcgctgccc acccggcggc ccatgttgat gagggcctcc tccaggggca cgcccagctt
    16921 gatctccttg acgaagagac cgaactcctg ggccagcggc ggctgggcct cgcgcgccac
    16981 gtgctcgatg gcctgcggga acgtgaggcc cgccttgaac gcattggcca tggcctgcag
    17041 cgcgtccacc agctgcacgt tgaacttctt gatgcgccgc ttgcggtagt gcttcaccag
    17101 gatgatcggc aggaagaagc cgaagatggt gcacaccacg cacaggatgg ggttgaagat
    17161 gatgtacgac aggatgccca gaaggcacat gctggcgatg ttgagcacca gcagctgacg
    17221 ggcatcgatg aagaggaaca tgtcgctcaa gtcgttcatc gacttgacga cgtagcgctc
    17281 ctgatactgc tcgtaggcct tcgccagcac ggtgaagatc accaggctga agaagaagac
    17341 cgatccggtg acgaggagga ggacgattcc ggccagcatg ggcgaggact tccttcagcg
    17401 acggggggag gccagcagcg gggaggaagg gatcaagcgg ggcctcaggg agtacccgag
    17461 gagcccacgg cgctcttctc cgaggcgctg cccttgatga tctggatgat ctcgcggcgc
    17521 ttctgctcga gcacgcgggt gcgctcgccc gacaggagcg tggtgatggt ggcgcggccg
    17581 cgctcctcga tcatgtccac gtcctcctcg ttgcgcagcg acagcgtgag gttgccgagc
    17641 tccgcggcca gggtgaggat ctccgcctcc tcggggatga ccatcagcgt gatgttgttg
    17701 tactcgcgct gggactcggg gatgaggttc acgttcgtgg tgcccgtcac cttgccggtg
    17761 gccaggacga tcacgttctg caggagcgtc accgccacgc tctcgtccgt ctgcggatcg
    17821 cggaaggtgc cgatcacgtc cacgtgatca ttgggacgca cccagccacc caccgacgtg
    17881 gtgacgcgcg agtcgatggt gacggcgcgc accttcttct gcaccttggt ggacaggcgc
    17941 tcggcggcct tggtcgtctc gaactggctc cacagcagcg ggtcacccgt ctgcagcgcc
    18001 acgagcacct tctggcccac cacgtagttg gccgagtccg gcttgaccac cgaggaggtg
    18061 acgaactgct cgggcacctg ccgctggctg atcatctcga aggtgatgac agtcccctcg
    18121 ggcagatcct gcgtggccac gaccaccggc accaggttcc agccccggcg tacgtccgcc
    18181 tccttcttct tgatggcgga ccacgcgatg attccagcca gcaggccgag gcccagcgcg
    18241 atgatcagag gagtcttacc cttcaacatg tcttgaggac ctccaaaagc ggggggtcgc
    18301 ccgtgcaggg cgggaatgcg gcggtgcggg agctgttctg caaagcgggg gcccggggca
    18361 ccagcgggcg gggatgttat ccagtagtca tggaaggtgt caaagacgcg agagtgcggt
    18421 tgcctgcctg gcctacccac cgcgtcgacc gtcccggata cctgacacgt tgcttcgccg
    18481 gtggactccc ctctggcggc cacctgaccg atacacgccc tggcatgaat gtcgctagat
    18541 ggcggcattc atgagtcaac actccccccc gtcccgggaa tccgggcaag cggcggtcga
    18601 atcggcactg gtgctgccgc tgatggtctt cctgggcctg ggcctcatcc agctgacgat
    18661 gatgcagcag gcgaagttga tgaccgagta cgcggcgtac tgcgcggcgc gcacgggaat
    18721 cgtgtggaac ggcaacaacg agcgcatgca cgacgcggcc atcatcgcgc tcttgcccac
    18781 catgggccgc acggacaccc tgctccacct gggcaagacg tgggcgctgg cgcagctcta
    18841 cgacgaggcg ctgcagctgc tggcctggcc gaacaagaag cagagcgatg atccgaaggc
    18901 gggctcgacg aagacctcga gcgtgccggc ctcggtgaac ggctccaacc tgttcggcca
    18961 ggtgcgcgtc gacacggtga atccctcctg gtactcgccc atcaagagcg tgtggaagct
    19021 gcgctcgggc gcgggctgga aggagctgga cttcgacggg ccggacacct acccgcaggt
    19081 gccgtcgctg gagtcgaaga tcgccaagtt cttcaacctg gccctgccgg acaacgacga
    19141 ggaggtctac cgcaaggcca cggtgctgag catccgggtg cgctactggt acgagctgcg
    19201 cgtgcccttc gccaactgga tcatcttcac gtcctggtgg gcggccaacg cgggggtgac
    19261 cctgggcggc gccatctaca agcccacgac cgactcgggc gcgcgcatca ccagcaagaa
    19321 gggcggcatg agcgaggtgg gcgcggtgcc cgtcaaggga ctggagcacc agcgcggcta
    19381 caactcgctc taccagccgg agatgaccgt gctctggatg ctggccaccg gcagcatccc
    19441 gctgctctcg aagtacgtgg gcaagcgcta cttcatcccg ctgacggcca cctacagcat
    19501 gcggatgcaa tcgaacttct actacaagtg gctgatgcac ctggaaccgg agtggggact
    19561 gtagagccat ggtgacccgt gcactacgac gcggcatgaa gcggcaggag ggccaggccc
    19621 tcgtgctcgc ctgtctgttg atgctcatcc tgagcatcgc gctcatcacg acggtgaaca
    19681 tcggccatgg ggtgcacgag cgcatccgcc tgcagaacac ggcggacgcg gcggcctact
    19741 ccacggcggc gatggaggcg cgcgcgttca acttctacgc gttcaccaac cgcacccagg
    19801 tgtcgcacta cgtgtcggcg atgatgtggc agtcgctcga ctcgttcctg ttctccatcc
    19861 aggcgttcct gacggacatc ttcgggttca tgcgcaccgt cggcccgtgt ttcccctcgg
    19921 actcacgcag cagttactgg atcatcgtct gcgccgtgct cgaccggatc ccctacgtca
    19981 acatcgtcat gaaggcgctg gacatcgtct acaaggcggt ccggctgatc ctcgacgtca
    20041 tgaagaaggt cttcccggcc atcgatcgcg ccattggaag gatcgtggtg cccgggcacc
    20101 ggatgctcaa cggggtgatg gccggtgcgt ccacggcggt gatgatgtcc acgtccacct
    20161 acgtgatggg cacctccaac aagatcatcg ccgcgaacga tcccaacgtg gactcgctca
    20221 tcccgcagac gctcgcgggg ctcatcaatc agtgcctcta caaccgcacc cactacaagc
    20281 aggccaacgg cacgccgttt tctccggtca accccttcaa ggaactggac cccacggtgc
    20341 gggacgagtc cagcaaggtc gcccgcgcca agcgggtgat ggcgggaatc accaacgcca
    20401 cgcgcttccc ctgtgacgcg aagacgagtc tgtgcccgga gacgttggtc accaagcgca
    20461 ccctgggtgc gctgctgccc atccccgact ggctcaagcc cctggagacc ttcctcgaca
    20521 acattcccaa gtggggccag acgcgctttc tcacctacaa gctgggctac ggcacggacg
    20581 agaacgaaac gggggccaag tccaagaagc gcaacaagat ccgcgagatg aacgatctgc
    20641 ccaactcccc catgggcatg atcgcccagg gagacatcct cgcctcggac gacccgtact
    20701 acatcaagct cgggccgagc cggctcggca ttgtcaacaa ccccttcagc tgccccaagg
    20761 agcgcagctc gaaggacaag cggacgtggc gcgactgctg gggagatccg cgcgaggaca
    20821 aggacagcac gctcaagacg agcatctggg ccttgagcaa gcacgagcgc aagggcggcg
    20881 cgcactggcg g
//
