LOCUS       NZ_CP022098            22652 bp    DNA     circular CON 17-FEB-2024
DEFINITION  Cystobacter fuscus strain DSM 52655 chromosome, complete genome.
ACCESSION   NZ_CP022098
VERSION     NZ_CP022098.1
KEYWORDS    RefSeq.
SOURCE      Cystobacter fuscus
  ORGANISM  Cystobacter fuscus
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Cystobacter.
REFERENCE   1  (bases 1 to 12349744)
  AUTHORS   Rupp,O., Goesmann,A. and Sogaard-Andersen,L.
  TITLE     Sequencing and comparative analysis of myxobacterial genomes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12349744)
  AUTHORS   Bruckskotten,M., Treuner-Lange,A., Rupp,O., Goesmann,A. and
            Sogaard-Andersen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2017) Department of Ecophysiology, Max Planck
            Institute for Terrestrial Microbiology, Karl von Frisch Str. 10,
            Marburg, Hessen 35043, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 09-AUG-2016
            Assembly Method                   :: Celera Assembler v. 8.1
            Expected Final Version            :: yes
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/17/2024 10:04:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,093
            CDSs (total)                      :: 10,016
            Genes (coding)                    :: 9,906
            CDSs (with protein)               :: 9,906
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 26 of 110
            Pseudo Genes (incomplete)         :: 101 of 110
            Pseudo Genes (internal stop)      :: 1 of 110
            Pseudo Genes (multiple problems)  :: 17 of 110
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:24:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7224211
            Orig. end                         :: 7246863
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22652
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="38"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22652
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22652
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12652](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12652
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            complement(442..1476)
                     /locus_tag="CYFUS_RS29345"
                     /old_locus_tag="CYFUS_005803"
     CDS             complement(442..1476)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013941029.1"
                     /locus_tag="CYFUS_RS29345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005803"
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="WP_095988237.1"
                     /transl_table=11
                     /translation="MKRAVKLVASLIVTLLFFWWAFQDADWESQLSVLKSANYAWVVPY
                     FGILTLIHLARTLRWGCLLSGMERVPFGKLNEASGIGFMMLLVLPFRLGEFARPLLIAQ
                     RSSIRRSAAMTSVVLERITDGMFVAVMMRLLLFFVPTTVPGMRYVKLGANLMFAGFGGL
                     LVFLLFSLWHQERAVRLVRSTVGRVVPGLADKVADVVDTFVGAMRQLPGPRQMVGFFLY
                     TLLYWGLNGAGMAVLSRAFGALSLTLFQAYVLNCVLVVGVMIPAAPGMLGTFHAAIKVG
                     LSLFLPASVVNSSGLAYANVLWLCQTLQQVGFGLLLMNAGHQSFKDLAGKLNKEQQASS
                     LPSA"
     gene            complement(1598..1807)
                     /gene="yacG"
                     /locus_tag="CYFUS_RS29350"
                     /old_locus_tag="CYFUS_005804"
     CDS             complement(1598..1807)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /gene="yacG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002620394.1"
                     /locus_tag="CYFUS_RS29350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005804"
                     /product="DNA gyrase inhibitor YacG"
                     /protein_id="WP_095992299.1"
                     /transl_table=11
                     /translation="MNVRECSICRKPVAPRAENPAFPFCSKRCRMVDLGRWLGEEYRVP
                     DRQVDEQEDELPTDQHPDRTPGDA"
     gene            1869..2855
                     /locus_tag="CYFUS_RS29355"
                     /old_locus_tag="CYFUS_005805"
     CDS             1869..2855
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631534.1"
                     /locus_tag="CYFUS_RS29355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005805"
                     /product="magnesium transporter"
                     /protein_id="WP_095988238.1"
                     /transl_table=11
                     /translation="MDAPGEAHFLLQGDRLSRDFVSVGVEDTVAQALEKMRAAPGSNEI
                     FYCYACDPAGRLVGVVPIRKLIRAAPDERIASLMFTRVVKLPVDAPDSLVEDFFVTYRF
                     LAFPVVDAEGRIVGVVEVGNFVDTFSDTLFDEVEGRVRDEVFRFVGLPENEMKQTRPVS
                     MALRRFPWLLVNIGGGFLAATVSRLFEQTVERLVVVAAFIPMVLVLSESLGVQTTAVSA
                     AMIANQRVDVPQMRREVLGTSLAGMMAAGVVALLGSLYSPHLAFPFVLFIAITLSTSLA
                     AGLGALLPFAFHRFRVDPHLASAPLVLAISDNVTLLTYFTLVTRLLG"
     gene            2881..3870
                     /locus_tag="CYFUS_RS29360"
                     /old_locus_tag="CYFUS_005806"
     CDS             2881..3870
                     /NRPS_PKS="Domain: PKS_ER (14-326). E-value: 4.1e-62.
                     Score: 202.0. Matches aSDomain:
                     nrpspksdomains_CYFUS_RS29360_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631532.1"
                     /locus_tag="CYFUS_RS29360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005806"
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="WP_095988239.1"
                     /sec_met_domain="ADH_N (E-value: 2.2e-08, bitscore: 33.1,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.7e-22, bitscore:
                     77.9, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVLRITRPGGPEVLEFEERPAPIPIGSELLVRVRATALNRADLL
                     QMSGRYAAPPGVPADVAGIEYAGEVLAVGPAVRRFQVGDRVMGLVGGGAFSEQLVTHER
                     EAMHVPTPLDFTQAAALPEAYLTAFDALVLQGGLRMGESVLIHAVASGVGSAAAQLCRA
                     MGARAFGTGRNAQKLARATEWGVEKTVLCDTQPPRFADTVKEATGGRGVDLALDLVGGD
                     YLPETLRAMALQGRVLLVGLVAGRRAEVDLEGVLARRLHITGTVLRSRPPEEKMALVQA
                     AERSLLPLFHSKALTPVVDAICPMKQAREAFTRMANNETVGKLVLHWE"
     aSDomain        2923..3858
                     /ASF="ER domain putatively catalyzing 2S-configuration
                     product formation"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CYFUS_RS29360_PKS_ER.1"
                     /evalue="4.10E-62"
                     /label="CYFUS_RS29360_PKS_ER.1"
                     /locus_tag="CYFUS_RS29360"
                     /protein_end="326"
                     /protein_start="14"
                     /score="202.0"
                     /tool="antismash"
                     /translation="LEFEERPAPIPIGSELLVRVRATALNRADLLQMSGRYAAPPGVPA
                     DVAGIEYAGEVLAVGPAVRRFQVGDRVMGLVGGGAFSEQLVTHEREAMHVPTPLDFTQA
                     AALPEAYLTAFDALVLQGGLRMGESVLIHAVASGVGSAAAQLCRAMGARAFGTGRNAQK
                     LARATEWGVEKTVLCDTQPPRFADTVKEATGGRGVDLALDLVGGDYLPETLRAMALQGR
                     VLLVGLVAGRRAEVDLEGVLARRLHITGTVLRSRPPEEKMALVQAAERSLLPLFHSKAL
                     TPVVDAICPMKQAREAFTRMANNETVGKLVL"
     CDS_motif       3301..3363
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CYFUS_RS29360_0001"
                     /evalue="2.00E-07"
                     /label="PKSI-ER_m5"
                     /locus_tag="CYFUS_RS29360"
                     /protein_end="161"
                     /protein_start="140"
                     /score="23.5"
                     /tool="antismash"
                     /translation="GESVLIHAVASGVGSAAAQLC"
     gene            3994..5013
                     /locus_tag="CYFUS_RS29365"
                     /old_locus_tag="CYFUS_005807"
     CDS             3994..5013
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015267 - channel activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014400071.1"
                     /locus_tag="CYFUS_RS29365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005807"
                     /product="aquaporin"
                     /protein_id="WP_232536877.1"
                     /transl_table=11
                     /translation="MNRPRRLVVEALGCGLLVVALEGAHHGAEHLGVSATDGRLFMSLA
                     TGAVLACLTLVLRPFSGAHFNPALTFADALEDGTPWKDVPLYVLAQFSGGLAGRLIAHL
                     MCGEPLLLTALVPAATSAHFLTELVSTFGLLIVVRGCARNRPSATPFAVAAYVATTVWF
                     TDSRSLANPALVLARAASSQTSAVHPLDVETLVVSQLLGAALAVCLFRWLQRPARASPP
                     GPWTIICLSPQEGVAELAASLLNGLAAPARVQAIASPSHEELLEAQASERQAATLVLRL
                     VPAGASPDAALLGEVWQLPPLELRAVLRGRLQRFLRERGWLRLYAVGDPFAPRPGDTR"
     gene            complement(4903..6033)
                     /gene="dusA"
                     /locus_tag="CYFUS_RS29370"
                     /old_locus_tag="CYFUS_005808"
     CDS             complement(4903..6033)
                     /EC_number="1.3.1.-"
                     /EC_number="1.3.1.91"
                     /GO_function="GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0002943 - tRNA dihydrouridine synthesis
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dusA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011552359.1"
                     /locus_tag="CYFUS_RS29370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005808"
                     /product="tRNA dihydrouridine(20/20a) synthase DusA"
                     /protein_id="WP_095992300.1"
                     /transl_table=11
                     /translation="MTARPPASTVPSHRLSVAPMMDWTDRHDRYFLRLLSKRTRLYTEM
                     VTTGAILFGDKPRHLDFSQEEHPLALQLGGSDPAQLAECVRIAEQWGYDEVNLNVGCPS
                     DRVQNGMFGACLMAKPDLVARCVEAMRGATRLPVTVKHRLGIDDLDSYELLTQFVRTVS
                     GAGCDTFIVHARKAFLQGLSPKENREIPPLRYEWVRQLKTDFPHLTISLNGGVKSLEEA
                     RAHLEWADGVMIGREAYQNPYLLALADSTIFGETAPAPTRRQVVEALQPYVEELLARGE
                     YLSRVTRHILGLFAGLPGARGWRRVLSERGTRPGAGLEVLRDALAQVPAHVLDSPATPP
                     SAGVPGPRSEGVSDGVQAQPAALAQEALEPSAQHRA"
     gene            6164..7201
                     /locus_tag="CYFUS_RS29375"
                     /old_locus_tag="CYFUS_005809"
     CDS             6164..7201
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631528.1"
                     /locus_tag="CYFUS_RS29375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005809"
                     /product="agmatinase family protein"
                     /protein_id="WP_095988241.1"
                     /transl_table=11
                     /translation="MPAAFDPSAAAPQDSGIFGLPHTPEEAHVVLIPVPFEATTSYGGG
                     TSDGPSAVLQASRQVDLFDVETGRPYERGIALLPEPEQWRAWNTRAKERAVPIIEAGGI
                     DASQPELMAASAEVNGLCEQLHEAVYQTAKEWLGKGKRVGAVGGDHSISYGIIRAHAEK
                     YPGLGVLHLDAHADLRDAYEGFAWSHASIMHNVAERIPGVKSLVQVAIRDMSEDEHRYI
                     ESSGGRVKAFFDTELQRKRFDGIPWNRQVDEIVQQLPQLVYLSFDIDGLDPTLCPHTGT
                     PVPGGLSFPEAVALISGVVRSGRTIVGFDLTEVAPDPEGGEWDGNVGARLLYKMIGWML
                     KSERP"
     misc_feature    complement(6169..6178)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            complement(7219..9537)
                     /locus_tag="CYFUS_RS29380"
                     /old_locus_tag="CYFUS_005810"
     CDS             complement(7219..9537)
                     /EC_number="3.2.1.-"
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631526.1"
                     /locus_tag="CYFUS_RS29380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005810"
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="WP_095988242.1"
                     /transl_table=11
                     /translation="MRLGMFCAVGALLGAMSGAARAAAPSAYDAVDPFIGTGGKGHTFP
                     GAVAPFGMVQLSPDTDVRPFKQSYDWAAGYRHDDPTILGFSHTHFSGAGHSDLGDVLLT
                     PFSGTVKLDPGEADKPGSGYRSRFSHDGEIARPGYYAVTLSDSRVRAELTAGLRTGMHR
                     YTFEGKAAAGVLLDLRSSIYNYPGKVLWSRVRVANDGTVTGYRETRGWAPGRKLFFAIR
                     FNKPLISHALHDRDEAIVYKGFRQPGRGPADRAQLEGRALEGVFEFGELDGPLIVKVAI
                     SAVSEDNALLNLDSEQAGFDFEALRGATRAAWEQALGAVELDAPAPMRTSVYTALYHSL
                     IAPSVFTDADGRYRGPDDQVHKAEGFTFHSTFSLWDTFRAEHPLLLLVQPEKRNSDMVN
                     SLLASQRHSPYGILPVWQFHGLETWTMIGYHSVPVIADAWLKGIRGFDANAALDAMVKS
                     ATYAPYGGLGDYMSLGFVPIDREPEAASKTVEYAYDDWTIARLARALGKEDIARTFEAR
                     AGNWRNTFDAKSGFIRARRADGAFRTPFDPTAINYGSDYTEGNAWQYSWFVPQDLGGLI
                     KAMGGDAAVVKKLDAMFEYDISKLDYSHAEDIAGLIGQYIHGNEPSHHVAYMYSFAGAP
                     WRTQARLKQIVDSQYKPTPDGLSGNDDLGQMSSWLVFTALGFYPVTPGSNEYVIGRPFV
                     ERAALNLPNGKRFTVTAEGLSEANPYVGKVSLNGRPLERGFLRHEELLAGGSLHFVMQA
                     KPNTSWATKPQARPMSRAP"
     gene            10001..12652
                     /gene="lanKC"
                     /locus_tag="CYFUS_RS29390"
                     /old_locus_tag="CYFUS_005811"
     CDS             10001..12652
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631519.1"
                     /locus_tag="CYFUS_RS29390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005811"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_095988244.1"
                     /sec_met_domain="Pkinase (E-value: 5.2e-12, bitscore: 44.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 5.8e-31, bitscore:
                     106.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGIERRARENIHLFTLLHPERYESLDAYQSKSAGFRELLVRLLP
                     ASWTIGRKSGIWCEAQPPEPSFPDTGFKIHVSTAHDRARELLTTVVPLLVAERVAFKVL
                     VDEFVLDLSNSHMWARGASGKFITLYPADVGQLKRLLEQLHGVTKDFVGPYILSDKRYK
                     GSHVLFYRYGAFRGLRHLNAYGEQVPHLRMTDGRLLPDPRPPFFTLPPGVIDPFPDDDQ
                     GATEEPLLHGRYKALSAMSSSSKGGVYRCLDLTSRAEVVLKEARPLVNRGRKNPCDAVD
                     CLENEYRILKRLEATGLAPRALDFFQDWEHSFLVMELARGRKLSAHIASGQLSLLASPT
                     PGVDEVRRFGETFLAVSRKLISALRTIHSQGVVIQDISPKNILFDLERDQLTFIDFEAA
                     LDLQNPEQGPVIRLFTPGFGVERPAGSVPTFRDDHQALSRVLGDFLYPPTPFFTLAPHQ
                     REPMLTHFAQEKGIPEAFVRLIFGIEQDFQRADELLAEAERSLGDIHSARPVTPRRDDD
                     ALRESLEGIIRYIVDQIHTGEDPLELPTDYRRFTTNRLSAAYGASGIALFLQRVGRPPP
                     EVFLEALLHEASQIDNQRYAPGLYIGSAGIAWTLLELGWRKEAEALLDVAARSPLLFEN
                     ADLFYGGGGFGLTNLFFFDRLGDERYLQRAIQVFDTLKPGIQSSARGYFFENNGDVYHG
                     LAHGASGLACFCLKLHQATGRQEHLDAAIRLLDFDLSSAERSNGHPRFRRSRRESVFYP
                     YWHIGSAGIGCVALRFYDVLRDERYAREARSIASSLAGNYSVFPTNFAGMAGLGGFFVD
                     LYRYTGEEVWRTEARRFLERVMLFALDRPAGLVFPGEDLLRVSTDYGTGSAGTGSFIHR
                     LLTGGGIPYLDF"
     misc_feature    complement(12925..12939)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.37"
                     /tool="antismash"
     misc_feature    13217..13231
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.89"
                     /tool="antismash"
     misc_feature    complement(13247..13262)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.16"
                     /tool="antismash"
     misc_feature    complement(13256..13271)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     gene            13281..16076
                     /locus_tag="CYFUS_RS29400"
                     /old_locus_tag="CYFUS_005813"
     CDS             13281..16076
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014399763.1"
                     /locus_tag="CYFUS_RS29400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005813"
                     /product="hypothetical protein"
                     /protein_id="WP_095988245.1"
                     /transl_table=11
                     /translation="MKARDMALQRDVRKAALTAMLLVGCLLSHEVSASSFTLFESGQVR
                     PLALSPCGTRLFAVNTPDNRLEVFQVLPTGLLHISSVPVGLEPVAVAARSDNEVWVVNH
                     LSDSVSVVDLSPNGHGGSVVRTLLVGDEPRDIVFAGPGRSRAFITAAHRGQNVPFNPQF
                     STPGIGRADVWVFDAHNLGTSLAGNPLSIVTLFSDTPRALAATPDGSRVYAAAFHSGNR
                     TSIVHEILVPNGGESVGGVPGPNVNFEGKPAPETGVLVKFNGTDWLDSLGRSWTDKVRF
                     SLPDKDVFVIDATANPPAQLSGPSGYYSGVGTILFNMAVNPVSGKVYVSNTEARNDLRF
                     EGPGTFAGSSLRGHLHESRISVLGSSGVAPRHLNKHINYGICCAALPNAENDKSLAQPL
                     GMVVTTDGATLYVAAFGSSKLGVYSTAALEADTFVPDTANQIPLSGGGPTGMVLDETNG
                     RMYVLTRFDNAISVVNTATKQEVAHLPLFNPEPPSVVAGRPYLYDARKSSSHGDSSCAS
                     CHIFGDFDSLDWNLGNPDAAYKLNKNPIATTPPEFGTDPTFGQDPNFHPVKGPLATQSL
                     RGMANHGPMHWRGDRSGADTATNAQPDSGAFNETEAFKQFNPAFMDLLGRSAQLTPAEM
                     QRFSEFILQVVYPPNPVRNLDNSLTSAQQAGRDFFFNTTSFFHGPCQSCHRLDPNANPS
                     AGPFKGFFGTDGSSAFVATAIFPKTPHLRNLYQKIGMFGVAYPFGFLPPDPFMGDQIRG
                     FGFNSDGSIDTMMRFNSGFDHDPIFNSVGIPNTPAGHQAKLDMAEFLLAFDTNLAPIVG
                     QQVTLTPINALVAGPRVNLLMARANVGECDLVVKGRDAQKEVGFLYMGNGQFKSDQQSV
                     PLVADAALRLLVTTSLGALTYTCTPPGSGQRIGIDRDLDGHLDGDEQTHGTDPANPLSH
                     P"
     gene            16167..16895
                     /locus_tag="CYFUS_RS29405"
                     /old_locus_tag="CYFUS_005814"
     CDS             16167..16895
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039701.3"
                     /locus_tag="CYFUS_RS29405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005814"
                     /product="DUF6249 domain-containing protein"
                     /protein_id="WP_095988246.1"
                     /transl_table=11
                     /translation="MKSQLLTLCLLAALPGGAWAQSEAQAPAVPPPAVPMPPQLAAQRQ
                     QAEERRNALEAQRQQAEEHRNALEAQRQELEADIQRLESEARQIDPEARLDSNQLFALL
                     QERERRMSSQADSDVAPAIISISLFSCLLTGFLAWLVANNRKSHLLHQTVRMMVEKGAE
                     IPQGLLAPPPKKPSDLRRGIILSATGVGLTIFLAALPHSDGAWGVGVTLFFLGLGHLLV
                     WRLQQGRGALASHLSPESPL"
     gene            16909..17460
                     /locus_tag="CYFUS_RS29410"
                     /old_locus_tag="CYFUS_005815"
     CDS             16909..17460
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /locus_tag="CYFUS_RS29410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005815"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_095988247.1"
                     /transl_table=11
                     /translation="MSSPPETPSDTELITRVLVRDDRSAFGELVARHQSAVRALLRRLT
                     GGDVAQADDLAQETFLRAYRGLRGYRGGAKFSSWLYRIACNTYFSQDRSSRNEPLALPT
                     VEEELPSAIHLPDVLLERYDLERALSTLKPRERAALVLTYANELTHEEAAVVLDCPLGT
                     LKTHVARAKEKLRRRFEETP"
     gene            17457..17744
                     /locus_tag="CYFUS_RS29415"
                     /old_locus_tag="CYFUS_005816"
     CDS             17457..17744
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS29415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_005816"
                     /product="hypothetical protein"
                     /protein_id="WP_095988248.1"
                     /transl_table=11
                     /translation="MNGHDDEAWIQSMLQRRPPSELSDGGFQHRVLQRLPPRERPVRRM
                     IALGATWGVTATFSLLSWDAGMFSSSGMVSPAVPFSLGTALLWYVVDALR"
     gene            complement(17749..18333)
                     /locus_tag="CYFUS_RS29420"
                     /old_locus_tag="CYFUS_005817"
     CDS             complement(17749..18333)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631499.1"
                     /locus_tag="CYFUS_RS29420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005817"
                     /product="hypothetical protein"
                     /protein_id="WP_095988249.1"
                     /transl_table=11
                     /translation="MRHWMRVGCMVLSASAMACASQLARSPAPTSADEAAPVAVSAGGG
                     GGATVDTGQFPTEDTVAEPVGAKHDLYEQVARELKIKREKPKGLDEGTGGSGVSAEERH
                     LCANALNSPEHVTVVSGIINFRSNGLVVVDVPGKGPVKLRTDDATCTVQADKALPPEAL
                     SEGTEARVAYVEDAGEPTARVIRAEPMRSLR"
     misc_feature    18375..18391
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.99"
                     /tool="antismash"
     gene            complement(18490..19398)
                     /locus_tag="CYFUS_RS29425"
                     /old_locus_tag="CYFUS_005818"
     CDS             complement(18490..19398)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002613594.1"
                     /locus_tag="CYFUS_RS29425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005818"
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_095988250.1"
                     /transl_table=11
                     /translation="MGLDLMDLRLFLLVVETGSITHGAERAHLALASASARIRGLEDEL
                     GVALLERERRGVRPTPAGRALAQHARAVLRQVENLRGELGGYAGGVRGQVRLLSNTAAL
                     TEFLPEALSAFLTAHPEVDVELEERLSHEIVQAVAEGRAEVGLVADTVELGALETFAFQ
                     EDRLVVVMARGHPLAARRTVTFAEVLDEPFVGLGEGSALQEHLAWHAARLGRRPRYRVR
                     LRSFDALCRMVERGVGVGVIPEAAARRCQRSMAIRRVALSDVWATRRLILCVRDHEALS
                     VQARLLVDALRADGPSRRGRG"
     gene            19508..20263
                     /locus_tag="CYFUS_RS29430"
                     /old_locus_tag="CYFUS_005819"
     CDS             19508..20263
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378335.1"
                     /locus_tag="CYFUS_RS29430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005819"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_095988251.1"
                     /transl_table=11
                     /translation="MNLLSTFPWLLGAGLLAGAMNAVAGGGTFVTLPALVLAGVPSVVA
                     NASSTVALFPGGLASTWAYRADLSPPRGVSLRALVVVSLAGGLVGSLLLVLTPRAAFDR
                     LLPWLLLLASGVFALGARPGLMPSSRVRSSPAVLLSLQFLLAIYGGYFGGAVGIMMMAV
                     WSLLGRSDLKVLNPLKALLVTATNTIAVLCFVVLGAVSWPETLLVLGAAVVGGYAGARL
                     ARRMDSRHLRLGVTGLSLLLTIAYFVRAG"
     gene            complement(20288..21550)
                     /locus_tag="CYFUS_RS29435"
                     /old_locus_tag="CYFUS_005820"
     CDS             complement(20288..21550)
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF018434.4"
                     /locus_tag="CYFUS_RS29435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005820"
                     /product="glycosyltransferase"
                     /protein_id="WP_095988252.1"
                     /sec_met_domain="MGT (E-value: 7.9e-37, bitscore: 126.6,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATFLVLAYGEAGHTLPMLSIVEGLIRRGHRALVYAPRKFTHGV
                     VAAGGESREGRTFGDPFERMMQLRASRKQRPVHQVVRDVVRGRAGMVGEIVRMAREWED
                     VIRTERVDGVVSFMSPAARYAAELTGRPFASVGPNPLMLFGADGKMVLPPNPMMKYLPR
                     GLLDSLMGLALPLARCREELGLPPRKGGPSEFFHTIMSDTLHLVTVHEGFYPPGPRGPG
                     QLCVGPMSYSLPRPQAAPFPVDTLAPGTVLVSTTTLPMDGGLFRRTLEALAPLKVPLLA
                     TAAGAADIPEGLGAHVRLESFVPHDQVLPHVSALVTHGGWGTTGRALRQGVPMLITPLF
                     GDQPLIGARLAEMGLAYHLPRKQATKEAIQKALAALLQDTALHQRVRAVAQQLQALDSP
                     RLAAEALEKLVARPGSLRSAA"
     gene            complement(21729..22586)
                     /locus_tag="CYFUS_RS29440"
                     /old_locus_tag="CYFUS_005821"
     CDS             complement(21729..22586)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002622577.1"
                     /locus_tag="CYFUS_RS29440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_005821"
                     /product="zinc metalloprotease"
                     /protein_id="WP_232536878.1"
                     /transl_table=11
                     /translation="MSGKFAVVLGSMLALGGCTEVEQAPAEEVTQQVVRGCATQELSAE
                     EKQSVEQALAGRVRAQARAAGSVNINVYWHVINNGTSTSQGNISDAAIASQISVLNAAY
                     ANTPFKFTLKATDRTTNSSWYTCSGGACEKKMKAALRQGTAADLNIYSNNMGQGLLGWA
                     TFPSSYASQPSLDGVVILYSSLPGGTAAPYNEGDTATHEVGHWLGLYHTFQGGCTGSGD
                     YVSDTAAESSAAFGCPTGRDTCTTAGVDPITNFMDYTDDSCMNTFSTGQNDRMDSLVQQ
                     YRGL"
     misc_feature    complement(22628..22641)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.7"
                     /tool="antismash"
     misc_feature    22639..22652
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.02"
                     /tool="antismash"
ORIGIN
        1 cgccgcgaag aggtcgagct tctcctcgaa cagcgtctcg tactggcgca gctcgtagcc
       61 gaagagcgga aaggactcgg tgaaggagcc gcgcccgagg atcacctccg cgcgtcccct
      121 ggccagggcg tcgagcgtgg agaagcgctg gaacacgcgc acgggatcgt ccgagctcag
      181 caccgtcacg gccgagccga gatggatgcg ggtcgtgcgc gtggcgatcc ccgcgagcac
      241 gacctcgggc gcggagacgg cgaagtcggc ccggtggtgc tcgcccacgc cgaagaagtc
      301 gaggccgagc tcgtcggcga ggacggcctg ctccacgacg tcgcggatga cctgcgcctg
      361 cgagagcggc tcgccaccgg ggccgagggt gacatccccg aaggtgtcca atccaagttc
      421 cagagatctt gccatgcgaa gtcaggccga gggcagcgag gaggcctgtt gctccttgtt
      481 cagcttgccg gcgaggtcct tgaaggactg gtggcccgcg ttcatcagca ggagtccgaa
      541 gcccacctgc tgcagcgtct ggcacagcca cagcacgttc gcgtacgcca gcccgctgct
      601 gttgaccacc gaggcgggga ggaacagcga caggcccacc ttgatggcgg catggaaggt
      661 gccgagcatg ccgggcgcgg cgggaatcat cacgcccacc accagcacgc agttgagcac
      721 gtaggcctgg aacagcgtca ggctcaaggc gccgaacgcg cgcgacagca cggccatgcc
      781 cgcgccgttg agtccccagt agaggagcgt gtagaggaag aagcccacca tctggcgagg
      841 cccgggcaac tgccgcatgg cgcccacgaa cgtgtccacc acgtccgcca ccttgtccgc
      901 gaggcccgga accacccggc ccaccgtcga gcgcaccagc cgcaccgcgc gctcctggtg
      961 ccacagcgag aacagcagga agacgagcag acccccgaac cccgcgaaca tcaggttggc
     1021 acccagcttc acgtagcgca tcccgggcac ggtcgtcggc acgaagaaga gcagcaggcg
     1081 catcatcacg gccacgaaca tgccgtccgt gatgcgctcg agcaccaccg aggtcatcgc
     1141 cgcgctgcgc cggatggagc tgcgctgggc gatgagcagg ggccgggcga actcacccag
     1201 ccggaagggc agcaccagca gcatcatgaa gccgataccc gacgcctcgt tcagcttgcc
     1261 aaagggcacc cgctccatcc ccgacaacag gcagccccag cgcagggtgc gcgccaggtg
     1321 gatgagcgtc aggatgccga agtacggcac cacccatgcg tagttggccg acttcaggac
     1381 ggacagctgt gactcccagt ccgcatcctg gaacgcccac cagaagaaga gcagggtcac
     1441 gatcagactg gcgacgagtt tcacggcacg tttcacgccc gcccgtatac cgcccccctc
     1501 gcctggactc caggggttcc ctgtctattc ccctgccagg agaccagggc cccggccgcg
     1561 gggcaccccg acggtcctgc cggcaacggg tctcgcctca agcgtctcca ggggtccgat
     1621 ccgggtgctg atccgtcggc agctcgtctt cctgctcgtc cacctgacga tccggtaccc
     1681 ggtactcctc gccgagccag cgccccaggt ccaccatgcg gcagcgcttg gagcagaacg
     1741 gaaacgccgg gttctcggca cgcggagcga ccggcttccg acagatggaa cactctcgaa
     1801 cattcatggc cacggcgtac tcataagcct tgatgtcgcc cacggccagc gcgtttagag
     1861 tcccgcgcgt ggacgctccc ggagaagcgc acttcctcct gcaaggtgac cggctctccc
     1921 gcgacttcgt ctcggtgggg gtcgaggaca ccgtcgccca ggcgctggag aagatgcgcg
     1981 cggcgcccgg cagcaacgag atcttctact gctacgcgtg cgatcccgcg ggccgcctgg
     2041 tgggcgtggt gcccatccgc aagctcatcc gcgcggcacc cgacgagcgc atcgcctcgc
     2101 tcatgttcac ccgcgtggtg aagctgccgg tggatgcgcc ggactcgctc gtggaggact
     2161 tcttcgtcac ctaccgcttc ctggcctttc cggtggtgga cgccgagggc cgcatcgtcg
     2221 gcgtggtgga ggtgggcaac ttcgtcgaca ccttctccga caccctcttc gacgaggtgg
     2281 agggccgcgt gcgcgacgag gtgttccgct tcgtcggtct gccggagaac gagatgaagc
     2341 agacgcgccc ggtgagcatg gccctgcggc gctttccctg gctgctcgtc aacatcggcg
     2401 gcggcttcct cgcggccacc gtgtcgcggc tcttcgagca gacggtggag cggctcgtcg
     2461 tggtggccgc cttcatcccc atggtgctcg tgctctccga gagcctgggc gtgcagacca
     2521 cggccgtgtc cgcggcgatg atcgccaacc agcgcgtgga cgtgccccag atgcgccgcg
     2581 aggtgctcgg cacgagcctc gccgggatga tggccgccgg ggtggtggcc ctgctgggca
     2641 gcctctactc cccccacctc gccttcccct tcgtgctctt catcgccatc accctctcca
     2701 cctcgctcgc cgcggggttg ggcgccctcc tgcccttcgc cttccaccgc ttccgggtgg
     2761 atccgcacct ggcctcggcg ccgctggtgc tcgccatctc cgacaacgtc accctgctca
     2821 cctacttcac cctcgtcacg cgcctgctcg gctagaggcg ctcttccgga gaacccatcc
     2881 atgcaggtcc ttcgcatcac ccgtcctggc ggccccgagg tgctcgagtt cgaggaacgc
     2941 cccgcgccca tccccatcgg ctcggagctg ctcgtgcgcg tgcgcgccac ggcgctcaac
     3001 cgcgccgatc tgctgcagat gagcggcagg tacgccgcgc cgccgggcgt ccccgcggac
     3061 gtggcgggca tcgagtacgc gggcgaggtg ttggccgtgg gcccggcggt gcgccgcttc
     3121 caggtgggcg accgggtgat ggggctggtg ggcggcgggg ccttctccga gcagctcgtc
     3181 acccacgagc gcgaggccat gcacgtgccc accccgctcg acttcaccca ggccgcggcg
     3241 ctgcccgagg cgtacctcac cgccttcgac gcgctcgtgc tccagggcgg cctgcgcatg
     3301 ggcgagtccg tgctcatcca cgccgtggcc agtggcgtgg gctcggcggc ggcgcagctc
     3361 tgccgcgcca tgggggcacg ggcgttcggc acggggcgca acgcccagaa gctcgcgcgc
     3421 gccaccgagt ggggcgtgga gaagacggtg ctgtgtgaca cccagccccc gcgcttcgcg
     3481 gacaccgtga aggaggccac gggcggacgc ggcgtggacc tggcgttgga tctggtgggt
     3541 ggggattacc tgccggagac gctgcgcgcc atggccctcc agggccgggt gctgctggtg
     3601 ggactcgtgg cgggccggcg ggcggaagtg gacctggagg gggtcctcgc ccgccggctg
     3661 cacatcacgg gcacggtgct gcgcagccgc ccgcccgagg agaagatggc gctcgtccag
     3721 gccgccgagc gcagcctcct gcccctgttc cactcgaagg cgctcacccc cgtggtggat
     3781 gccatctgcc ccatgaagca ggcgcgcgag gctttcacgc gcatggcgaa caacgagacg
     3841 gtgggcaagc tcgtgctgca ctgggagtga acaggcgcgc ccgtccacct ttgacccctc
     3901 ccggggcgtg acgtaccgtc ctcgactccc ccagcggaga gccacgccat ggtctcagcg
     3961 aaaccggccc tcacgacccc caccgaggga cacgtgaaca gaccccgccg cctcgtggtc
     4021 gaggcgctgg gctgtggact gctggtggtg gcactggagg gggcccacca tggcgccgag
     4081 cacctgggcg tgagcgccac ggacgggcgg ctcttcatgt cgctggcgac gggcgcggtg
     4141 ctcgcgtgcc tcacgctggt gctgcggccc ttctcgggcg cccacttcaa ccccgccctc
     4201 accttcgccg acgcgctgga ggatggcacc ccctggaagg acgtccccct ctacgtgctc
     4261 gcccagttct cgggaggact ggcgggccgg ttgatcgccc acctcatgtg cggcgagccc
     4321 ctgctgctca ccgccctcgt gcccgccgcc acctcggcgc acttcctcac ggagctcgtc
     4381 tccaccttcg ggctgctcat cgtggtgcgc gggtgcgcgc gcaaccgccc ctcggccacg
     4441 cccttcgcgg tggccgccta cgtggccacc accgtgtggt tcaccgactc gcgttccctg
     4501 gccaaccccg ccctcgtcct cgcgcgcgcg gcgagcagcc agacgagcgc cgtgcacccg
     4561 ctcgacgtgg agaccctcgt cgtctcgcaa ctgctgggcg cggcgctcgc ggtctgcctc
     4621 ttccgctggc tccagcggcc cgcccgcgcc tcgccgccgg gaccctggac gatcatctgc
     4681 ctgtctcccc aggagggcgt cgccgagctc gcggcctccc tgctcaacgg gctcgcggcg
     4741 ccggcgcgcg tccaggccat cgcctctcct tcccacgaag agctcctgga ggcccaggcc
     4801 tccgagcgcc aggcggcgac gctcgtgctg cggctcgttc cggcgggggc ctcaccggac
     4861 gcggccctgc tcggagaagt ctggcaactg cccccgctcg agctacgcgc ggtgctgcgc
     4921 ggacggctcc agcgcttcct gcgcgagcgc ggctggttgc gcctgtacgc cgtcggagac
     4981 cccttcgctc cgaggcccgg ggacacccgc tgacgggggc gtggcgggcg agtccaggac
     5041 gtgggccggc acctgcgcga gcgcatcccg cagcacctcc aggcccgcgc cgggcctggt
     5101 gccgcgctcg ctcagcaccc gccgccaacc cctcgctccg ggcagccccg cgaacaaccc
     5161 caggatgtgg cgcgtgacgc gtgacaggta ctcgccccgc gcgagcagct cctccacata
     5221 gggctggagg gcctcgacca cctggcgccg cgtgggcgcg ggagccgtct cgccgaagat
     5281 cgtcgagtcc gccagggcga ggaggtaggg gttctgatac gcctcgcggc cgatcatcac
     5341 cccatcggcc cactccaggt gcgcccgggc ctcctccagg gacttcacgc ccccgttgag
     5401 ggagatcgtc aggtggggga agtccgtctt gagctggcgc acccactcgt agcgcagcgg
     5461 gggaatctcc cggttctcct tggggctgag cccctggagg aaggccttgc gcgcgtgcac
     5521 gatgaaggtg tcgcaccccg ccccgctcac cgtgcgcacg aattgggtca gcagctcgta
     5581 cgagtcgaga tcatcgatgc ccaggcggtg cttgacggtg acgggcaggc gggtcgcgcc
     5641 gcgcatggcc tcgacgcagc gggccacgag gtccggcttc gccatgaggc acgcgccgaa
     5701 catcccgttc tgcacgcgat ccgaggggca gccgacgttg aggttcacct cgtcatagcc
     5761 ccactgctcg gcgatgcgga cgcactcggc gagctgggcc gggtcgctgc cgccgagctg
     5821 caaggccagc gggtgctcct cctgggagaa gtccaggtgc cggggcttgt cgccgaacag
     5881 gatggcgccc gtggtgacca tctcggtgta cagccgcgtg cgcttggaga ggaggcgcag
     5941 gaagtagcgg tcatgccgat cggtccaatc catcatcggc gcgacggaga gtcggtggct
     6001 cggcacggtg gacgcgggcg ggcgggcggt catcccacca tccatgccgg gcttcgggcg
     6061 tccatgcaag gccgcacggg gcctggcggc tccttgggcg ggcgaagagc cccccacggg
     6121 accgttgcgc tggccacgca ggaccttatc ctccgccgcc atcatgcccg ccgccttcga
     6181 tcccagcgcc gccgctcccc aggactccgg catcttcggc ctcccccaca ctcccgagga
     6241 ggcccacgtc gtcctcatcc ccgtgccctt cgaggccacc accagctatg gcggaggcac
     6301 ctcggacggt ccctcggccg tgctccaggc cagtcggcag gtggacctct tcgacgtgga
     6361 gaccggccgt ccctacgagc ggggcatcgc cctgctgccc gagcccgagc agtggcgcgc
     6421 ctggaacacc cgcgccaagg agcgcgccgt gcccatcatc gaggcgggag gcatcgatgc
     6481 ttcccagccc gagctcatgg ccgcttccgc ggaggtcaac ggcctgtgcg agcagcttca
     6541 cgaggcggtg taccagacgg cgaaggagtg gctcggcaag ggcaagcggg tgggagccgt
     6601 gggcggagac cactccatct cctacggcat catccgggcg cacgcggaga agtaccccgg
     6661 cctgggcgtg ctgcacctgg atgcgcacgc ggacctgcgc gacgcgtacg agggcttcgc
     6721 ctggtcgcac gcctccatca tgcacaacgt ggccgagcgc attcccgggg tgaagagcct
     6781 cgtgcaggtg gccatccgtg acatgagcga ggacgagcac cgctacatcg agtcctcggg
     6841 tggacgcgtg aaggccttct tcgacacgga gctccagcgc aagcgcttcg atggcattcc
     6901 gtggaaccgc caggtggatg agatcgtcca gcagctcccc cagctggtgt acctgtcctt
     6961 cgacatcgac ggcctggatc ccacgctgtg cccgcacacg gggacgccgg tgccgggcgg
     7021 actgtccttc cccgaggccg tggcgctcat ctccggggtg gtgcgctcgg gccggaccat
     7081 cgtcgggttc gatctcaccg aggtcgcccc ggatcccgag ggcggcgagt gggacggcaa
     7141 cgtgggcgcc cggctgctct acaagatgat cggctggatg ctgaagtccg agcggccgta
     7201 gcggaccgct cgacctccct acggggccct gctcatcggc ctcgcctggg gtttggtcgc
     7261 ccaggaagta ttgggcttcg cctgcatgac gaagtgcagg cttcctcccg ccaggagttc
     7321 ctcgtgccgg aggaagccac gctccagcgg gcggccgttc aacgacacct tgccgacata
     7381 gggattggcc tccgacaagc cctcggccgt cacggtgaag cgcttgccat tgggcaggtt
     7441 cagcgccgcg cgctccacga agggacggcc aatgacatac tcgttcgagc cgggcgtgac
     7501 gggatagaag ccgagcgcag tgaagaccag ccaggaggac atctggccca gatcgtcatt
     7561 gcccgacagc ccgtccggcg tgggcttgta ctggctgtcg acgatctgct tgagccgggc
     7621 ctgggtgcgc cacggagccc cggcgaaaga atacatgtac gcgacatggt ggctgggctc
     7681 gttgccatgg atgtactggc caatcagccc ggcgatgtcc tcggcgtgcg agtagtccag
     7741 cttcgagatg tcgtactcga acatggcgtc gagcttcttg acgaccgccg cgtcaccgcc
     7801 catggccttg atcaaaccac ccaggtcctg cggcacgaac caggaatact gccaggcatt
     7861 gccctcggtg tagtcgctgc catagttgat ggcggtggga tcgaagggcg tgcggaaggc
     7921 cccgtccgcc cggcgggcac ggatgaagcc gctcttggca tcgaaggtgt tgcgccagtt
     7981 gcccgcgcgg gcctcgaagg tccgggcgat gtcctccttg cccagggctc gggccaggcg
     8041 ggcgatggtc cagtcgtcat aggcatactc gacggtcttg gacgcggcct ccggctccct
     8101 gtcgatgggg acgaagccca gggacatgta gtccccgagc cctccatagg gagcgtaggt
     8161 cgcgctcttg accatggcgt ccagcgcggc gttcgcgtcg aagccccgga tgcccttgag
     8221 ccaggcatcg gcgatcaccg gcacggagtg atagccaatc atcgtccagg tctcgagccc
     8281 gtggaactgc cagacgggca ggatgccgta ggggctgtgc cgctgggagg cgagcagcga
     8341 attcaccatg tcgctgttgc gcttctccgg ctggaccagg agcagcagcg ggtgctcggc
     8401 ccggaaggtg tcccataggg agaaggtcga gtggaaggtg aaaccctcgg ccttgtgcac
     8461 ctgatcatcc gggccgcgat agcggccatc ggcgtcggtg aacacgctgg gggcgatcag
     8521 gctgtgatag agggcggtat agacgctggt gcgcatgggc gcgggcgcgt cgagctccac
     8581 cgcccccagc gcctgctccc aggccgcgcg ggtggcacca cgcagggcct cgaagtcgaa
     8641 gccggcctgt tcgctgtcca gattgagcag ggcgttgtcc tcgctgaccg ccgagatcgc
     8701 gaccttgacg atgagcggtc catccagctc gccgaactcg aagacgccct ccagcgcgcg
     8761 gccctcgagc tgcgccctgt ccgcggggcc tcgccccggc tggcggaagc ccttgtagac
     8821 gatcgcctcg tcgcgatcgt gcagggcatg ggagatgagc ggcttgttga agcggatggc
     8881 gaagaagagc ttgcgcccgg gggcccagcc gcgcgtttcg cgatagccgg tcaccgtgcc
     8941 atcgttcgcc acacgcacgc gcgaccacag caccttgccc gggtagttgt agatggacga
     9001 gcgcagatcc agcagcacgc ccgccgccgc cttgccctcg aaggtgtagc ggtgcatccc
     9061 ggtgcgcagc cccgccgtca gctcggcgcg cacgcgcgag tccgacaagg taacggcgta
     9121 gtagcccggc cgggcgatct ccccgtcgtg gctgaagcgc gagcggtagc ccgaacccgg
     9181 cttgtcggcc tcgcctggat ccagcttcac cgtgcccgag aacggggtga gcaacacgtc
     9241 acccaggtcc gagtggcccg cgccggagaa gtgggtatgc gagaagccca agatcgtcgg
     9301 atcatcgtgg cgatacccgg cggcccagtc gtagctctgc ttgaatggac gcacgtcggt
     9361 gtcggggctg agctgcacca tgccgaaggg cgcgaccgcg ccgggaaagg tgtggccctt
     9421 gccgcccgtt ccaatgaacg gatcgaccgc gtcataggcg gacggggccg ccgccctcgc
     9481 cgcaccgctc atcgccccca gcagggcacc caccgcgcag aacatcccaa gccgcattcc
     9541 ggactcccct ctttcgaaga acctcgccgc ggatgactat cacggccgcc cctcctccgg
     9601 gacaaggagt gacccgcggt ccaccaaggg gagccgccag actgtttctc catggatgtg
     9661 ttcttcggcc caggagtccc ggcggttgaa tccgtatctt ctcatcagta cgttcagcaa
     9721 ctcgccatgg tggcgagttg aaaggcggtt ggtcttgaac aacgtcctcg cattgcagaa
     9781 gctccccgcg gatacaggtg gggaagcagt tggaggcgac tcggcggatg gagggcagga
     9841 ggccactgcc tccaacctca gcttgcttga ttgtgaagca agttcgagct tgagtctcct
     9901 cttgtgttag tgagcaggcg ccggtcgagg tgccgtgcca tctgttgaca ggaaatcacc
     9961 tcccgagggc agcttccttc gggaggtccg gggaggatgc atgcgcggca tcgagcggcg
    10021 ggcacgggag aacatccacc tcttcacgct tctgcatccg gagcgctatg agagcctgga
    10081 tgcctatcaa tcgaagagcg ccgggttccg ggaacttctg gttcgcctgc tgccagcatc
    10141 ctggacgatc ggaaggaagt cagggatctg gtgcgaggcc caaccccccg agccctcttt
    10201 ccctgacacc ggcttcaaga tccatgtgtc cacggcgcac gatcgcgccc gggaactcct
    10261 gacgacggtc gttcccctgc tcgtcgccga gcgggtggcc ttcaaggtgc tcgtcgacga
    10321 gttcgtgctc gacttgagca attcccacat gtgggcgcgg ggcgcgagcg ggaaattcat
    10381 caccctctat cccgcggatg tcggtcagct gaagcggctc ctggagcaac tgcacggcgt
    10441 cacgaaggat ttcgtgggcc cctatatcct gtcggacaaa cggtacaaag gcagccacgt
    10501 cctcttctac cgttacggtg cgttccgggg cctgcggcac ctcaacgcct acggagagca
    10561 ggtgccccac ctgcggatga ccgatggccg cctgcttccg gatccacgcc cccccttctt
    10621 caccctgccc ccgggcgtga tcgatccctt cccggatgac gaccaggggg ccaccgagga
    10681 gcccctcctc catggccgct acaaggcgct ctcggccatg agttcttcct ccaagggagg
    10741 agtctatcgg tgcctcgatc tgacgtcccg ggcggaggtg gtgctcaagg aggcccggcc
    10801 cctggtgaac cgggggcgca agaatccctg cgacgccgtc gattgtctcg agaacgagta
    10861 ccggatcctc aagcggctgg aggcaacggg actggctccc cgcgcgctcg acttcttcca
    10921 ggactgggag cacagcttcc tcgtcatgga gctcgcgcgg ggcaggaagc tcagtgccca
    10981 catcgcctcc ggacaactgt ccctcctcgc gtcgcccacg ccgggtgtcg acgaggtgcg
    11041 gcgcttcggg gagaccttcc tcgcggtgtc caggaagctc atctccgcgc tccgcaccat
    11101 ccactcacag ggcgtggtca tccaggacat ctccccgaag aacatcctgt tcgacctgga
    11161 gcgagatcag ctcacgttca tcgacttcga ggccgcgctc gacctccaga acccggagca
    11221 gggtcccgtc atccggctgt tcacacccgg cttcggagtg gaaaggcccg cgggttctgt
    11281 tcccaccttc cgggatgatc accaggcctt gagccgggtg ctcggtgatt tcctctaccc
    11341 accgaccccc ttcttcacgc tcgcccccca ccaacgcgag cccatgctca cgcacttcgc
    11401 ccaggagaag ggcatcccgg aagccttcgt gcggctcatc ttcggaatcg agcaggactt
    11461 ccagcgggcg gacgagctgc tggccgaggc ggagcggagc ttgggggaca tccactcggc
    11521 gcggccagtc actccccgtc gagatgacga cgcgttgcga gagtccctcg aggggatcat
    11581 ccgctacatc gtcgaccaga tccacacggg ggaggaccct ctggagctgc ccacggatta
    11641 ccgccggttc accaccaatc gcttgagtgc cgcctatggc gcgtccggta tcgcgctctt
    11701 cctccaacgc gtgggcaggc cgcctcccga ggtctttctc gaagccctgc ttcacgaggc
    11761 ttcccagatc gacaaccaac gctacgcacc cggtctctac atcggcagtg caggaatcgc
    11821 gtggacgctg ctggagctgg ggtggaggaa agaggccgag gcgctcctgg atgtcgcggc
    11881 gcgctctccc ctgctcttcg agaacgccga tctcttctac ggaggtggcg gattcgggct
    11941 cacgaatctg ttcttcttcg accggctcgg ggatgagagg tatctccagc gggcgatcca
    12001 ggtcttcgac acgctgaagc caggcatcca gtcatccgca cgagggtact tcttcgagaa
    12061 caacggagat gtctaccatg gcctggcgca tggcgcctcc gggctcgcct gtttctgtct
    12121 gaagctccat caggcgaccg ggcgacagga gcacctcgat gccgcgatcc ggctcctgga
    12181 cttcgacctg tcgagtgccg agcggagcaa cggccatcca cggttccgcc gctcccggag
    12241 ggagtcggtg ttctacccgt actggcacat cgggagcgcg ggcattggct gtgtcgcgct
    12301 gcgcttctac gacgtgctcc gggacgagcg gtacgcccgg gaggcacgga gcatcgcgtc
    12361 atcgctcgcg ggcaactact ccgtgtttcc cacgaacttc gcgggcatgg cgggcctggg
    12421 gggattcttc gtggacctct atcggtacac cggcgaggag gtctggcgga cggaggcccg
    12481 gcggttcctg gagcgggtga tgctgttcgc gctcgatcgg ccggccggcc tcgtcttccc
    12541 tggcgaggat ctcctccgcg tctccacgga ttacggcacg gggtccgcgg gaaccggctc
    12601 gttcatccac cggctcctca cgggcggcgg cattccatac ctggacttct aaatccaggg
    12661 cgtcagctct tccgtgggtg gggtgaaaca agagcacctt ctcgtacatc cgcctcccat
    12721 ggaaggtgcc tgggcccggg cgtcagtggt cgtgcttgcg cgcgccgcgg cccttgccct
    12781 tgtgccgaca ctggtctcca tcccaatact cgctgggatg acactccggc cgggactgag
    12841 agcggactcc cttcctggag gaatgggtgg tgtcgcggac gtagatgcag cctggcagca
    12901 gaagcatgag ggcggggatg aggcagaaga tgggtttcat gggacccggc accctaacag
    12961 ggccgccgtg ccgcgatgaa gaggatctcc ccgggtgccc cgcggtacgt ggaccgtgtc
    13021 cgcttcttga agtcagacat cttcttgccg gagagctggc ggccagccag acacggggag
    13081 tgacaaccgt actcgctgtc ctcacacctt ctcaccaggg gtgacagccg ttcaaagcca
    13141 taagccgaaa aggctgcctg accgcgtcat ccgttgatcc gtcctttaca gaacacctcg
    13201 cgaaagcgca ccatcctggc catccttttc tttcttcgct gtattcgcga acagggattc
    13261 gcactcggcg tggaggtgga atgaaagcca gagacatggc gttgcagcgt gatgtgcgga
    13321 aagcggccct gaccgcgatg ctcctcgtgg ggtgcctgct gagccacgag gtgtccgcgt
    13381 catcctttac cctcttcgaa agtggtcagg tccgaccgct cgccctctcg ccctgtggca
    13441 cccgcctctt cgccgtcaac accccggaca accggctcga ggtcttccag gtcctgccca
    13501 cgggcctgct ccacatctcc tcggtgcccg ttggactgga gcccgtcgcg gtggcggcgc
    13561 gcagtgacaa cgaggtctgg gtcgtcaatc acttgtccga cagcgtgagc gtcgtggacc
    13621 tctccccgaa tgggcatggg ggctccgtgg tgcgcaccct gctcgtgggc gacgagcctc
    13681 gcgacatcgt cttcgccgga ccgggcagga gccgcgcctt catcaccgcc gcccaccgcg
    13741 gccagaacgt gcctttcaac ccccagttct ccacgccggg catcggccgg gcggacgtct
    13801 gggtgttcga tgcccacaac ctgggcacct cgctcgcggg caacccactg tcgatcgtca
    13861 ctctcttcag tgataccccg cgcgcgctcg ccgcgacgcc cgatggctcg cgcgtctacg
    13921 ccgccgcgtt ccactcgggc aaccgcacca gcatcgtcca cgagatcctc gtgcccaacg
    13981 gcggcgagtc ggtgggcggc gttcccggcc ccaacgtcaa cttcgaggga aagccggcgc
    14041 cggagaccgg cgtcctcgtc aagttcaatg gcacggattg gctcgactcg ctgggccgct
    14101 cctggaccga caaggtgcgc ttctccctgc cggacaagga cgtgttcgtc atcgatgcca
    14161 ccgccaatcc cccggcgcag ctctcgggcc cgtccggcta ctactccggc gtgggcacca
    14221 tcctgttcaa catggccgtc aacccggtga gcggcaaggt gtacgtgagc aacaccgagg
    14281 cccgtaatga cttgcgcttc gaggggccgg gcaccttcgc cggcagcagc ctgcgcggcc
    14341 acctgcacga gagccgcatc tcggtgctcg gctcctcggg cgtcgcgccc aggcacctca
    14401 acaagcacat caactatggc atctgctgcg ccgcccttcc caacgccgag aacgacaaga
    14461 gcctcgccca gccgctcggc atggtggtga ccaccgacgg cgccaccctg tacgtggccg
    14521 cgttcggctc ctcgaagctc ggcgtctact ccaccgccgc gctcgaagcc gacaccttcg
    14581 tgcccgacac cgccaaccag atccccctga gcggcggcgg ccccaccggc atggtgttgg
    14641 atgaaaccaa tgggcgcatg tacgtgctga cgcgcttcga caacgccatc tccgtcgtca
    14701 acaccgccac gaagcaggag gtcgcccacc tccccctgtt caaccccgag ccgccgagcg
    14761 tggtggcggg ccgcccctac ctctatgacg cgcgcaagag ctcgagccat ggcgactcgt
    14821 cctgcgcgag ctgccacatc ttcggcgact tcgacagcct ggactggaac ctgggcaacc
    14881 cggatgcggc ctacaagctc aacaagaacc ccatcgccac gacgccgccc gagttcggca
    14941 ccgatccgac ttttggccag gatcccaact tccacccggt gaagggtccg ctggcgaccc
    15001 agagcctgcg cggcatggcc aaccacggtc cgatgcactg gcggggggac cgctccggcg
    15061 cggatacggc gacgaacgcc cagccagaca gcggcgcgtt caacgaaacc gaggcgttca
    15121 agcagttcaa cccggccttc atggatctgc tcggacgctc cgcccagctc accccggcgg
    15181 agatgcagcg cttctcggag ttcatcctcc aggtcgtcta cccgcccaat cccgtgcgca
    15241 acctggacaa ctcgctcacg tcggcacagc aggcgggcag ggacttcttc ttcaacacca
    15301 cgagcttctt ccatggcccg tgccagtcgt gccaccggct ggatcccaac gccaacccca
    15361 gcgcgggtcc cttcaagggg ttcttcggta cggatggcag ctcggcgttc gtcgcgacgg
    15421 ccatcttccc caagactccg cacctgcgga acctgtacca gaagatcggc atgttcggcg
    15481 tggcctaccc cttcggcttc ctccctccgg accccttcat gggcgatcag atccgtggct
    15541 tcggcttcaa cagcgacggc tcgatcgaca cgatgatgcg cttcaacagc ggattcgacc
    15601 acgatcccat cttcaactcg gtcggcatcc cgaacacgcc cgcgggccac caggccaagc
    15661 tggacatggc ggagttcctc ctcgccttcg acaccaacct ggcgcccatc gtcgggcagc
    15721 aggtgacgct cacccccatc aacgcgctcg tggccggccc ccgcgtcaac ctcctgatgg
    15781 cacgcgcgaa cgtcggcgag tgcgatctgg tggtcaaggg ccgcgacgcc cagaaggaag
    15841 tgggcttcct ttatatgggc aacgggcagt tcaagagcga ccagcaatcc gtgcccctcg
    15901 tggccgacgc cgccctccgc ctgctggtga ccacgagcct gggggcgctg acctacacct
    15961 gcacgccgcc gggctcgggc cagcgcatcg gtatcgatcg cgacctcgac gggcacctgg
    16021 acggagatga gcagacccac gggaccgatc ccgccaaccc cctcagccat ccctgagcac
    16081 cggcgcggaa aaaaaatccg gggttgaatc caaggggctg ggctcgggag tcttcccgtc
    16141 gataaaaccg acgagaggac tccctcatga aatcccagtt gctcaccctg tgtctcctgg
    16201 ccgccctccc gggaggggcc tgggcccagt ccgaagctca agctcccgcg gtcccccctc
    16261 ccgccgtgcc gatgccccca cagctcgcgg ctcagcgtca gcaggcggag gagcgccgca
    16321 atgccctcga ggcccagcgt cagcaggcgg aggagcaccg caatgccctc gaggcccagc
    16381 gccaggagct ggaggcggac atccagcggt tggagtccga ggcccggcag atcgatcccg
    16441 aggcacgtct cgattccaat caactcttcg cactcctcca ggagcgcgag cggcggatgt
    16501 cgagccaggc cgattccgac gtggcccccg ccatcatctc catctccctc ttcagctgcc
    16561 tgctgacggg tttcctcgcg tggctggtgg ccaacaaccg caagagccat ctgctccacc
    16621 agacggtgcg catgatggtg gagaaggggg cggagatccc ccaggggctg ctcgcgcctc
    16681 cgcccaagaa gccctcggat ctgcggcggg gcatcatcct gtccgcgacg ggagtagggc
    16741 tgacgatctt cctggccgcc cttccccatt cggatggcgc gtggggcgtg ggggtgacgc
    16801 ttttcttcct cggcctggga cacctgctcg tctggcgcct gcagcaaggc cgcggcgcgc
    16861 tcgcgtcgca cctctcgccc gagtccccgc tgtagccgcc cgagcgtcat gtcctcccct
    16921 cctgaaaccc cttcggacac cgagctcatc acgcgcgtgc tcgtgcggga tgaccggagt
    16981 gcctttggcg agctggtggc gcggcaccaa tccgcggtgc gcgccctgct gcggcggctg
    17041 accgggggag acgtggcgca ggcggatgac ctggcgcagg agacgttcct gcgggcctac
    17101 cgggggctgc gtggctaccg gggcggggcg aagttctcct cctggctcta ccgcatcgcc
    17161 tgcaacacgt acttcagcca ggatcggagc agccggaacg agcccctggc gctgcccacg
    17221 gtggaggagg aactaccctc cgcgatccac ctgccggacg tgctcctgga gcgctacgat
    17281 ctggagcggg cgctctccac gctcaagcca cgagagcggg ccgcgctcgt gctcacctac
    17341 gccaacgagc tgacccacga ggaggcggcg gtcgtcctcg actgtccgtt gggcacgctc
    17401 aagacccacg tcgcgcgcgc gaaggagaag ctgcgccgac gattcgagga gaccccatga
    17461 acggccatga tgacgaggcc tggatccaat cgatgctcca gcggcggccg ccgtccgagc
    17521 tgtccgatgg cggtttccag caccgggtgc tccagcgcct gcccccgcgc gagcggcccg
    17581 tgagacgcat gatcgccctg ggagccacct ggggagtaac ggccacgttc tccctgctgt
    17641 cctgggacgc ggggatgttc tcctcctcgg gaatggtgtc ccccgccgtc cctttcagcc
    17701 tcgggacggc cctgctctgg tatgtcgtcg atgccctgag gtgagcgact aacgcaggga
    17761 gcgcatgggc tcggcgcgaa tcacccgagc cgtgggctct cccgcgtcct ccacgtaggc
    17821 cacgcgggcc tcggtgccct cgctcaaggc ctcgggaggc aacgccttgt ctgcctgcac
    17881 ggtgcaggtg gcgtcatccg tgcgcagctt cacgggtccc ttgcccggca cgtcgaccac
    17941 caccagcccg ttggagcgga agttgatgat gccggagacc accgtgacgt gctcggggga
    18001 gttcagcgcg ttggcgcaca gatgcctctc ctccgccgag acgcccgagc cacccgtgcc
    18061 ctcgtccagg cccttgggct tctcacgctt gatcttcagc tcccgggcca cctgctcgta
    18121 gaggtcgtgc ttcgccccca cgggctccgc cacggtgtcc tccgttggga attggcccgt
    18181 gtccacggtg gccccaccac cacctccggc gctcaccgcg acgggggccg cctcgtccgc
    18241 gctcgtgggt gctggtgaac gggccaactg gctcgcacac gccatcgcgc tcgcgctcaa
    18301 caccatgcag cccacccgca tccagtgcct catcggtccc tccccgtgtg gatcgcgaag
    18361 acctctcgga gccgtcctga tgaactaggc actcccccat tggaggacca ctgagcccca
    18421 caccttggac cttcacccag ggcaccgcct gcttgttcgc ccgcctggaa ggacgacagc
    18481 ccaaatggct catccacgtc cacgccgact gggcccgtcc gcccggagcg catcgacgag
    18541 cagccgggcc tggacggaca gggcctcgtg gtcgcgcacg cacaggatga gccggcgtgt
    18601 ggcccagacg tcgctcaacg ccacccggcg gatcgccatc gagcgctgac agcgccgggc
    18661 cgcggcctct ggaatcacgc ccacgcccac gcctcgctcc accatgcggc agagcgcatc
    18721 gaagctgcgc aggcgcaccc ggtagcgcgg cctccgtcca aggcgcgccg catgccacgc
    18781 caggtgctcc tggagcgcgc tgccctcgcc cagacccacg aagggctcgt cgagcacctc
    18841 ggcgaaggtg accgtccggc gcgccgcgag cgggtgccct cgcgccatca ccaccaccag
    18901 ccggtcctcc tggaacgcga acgtctccag cgcgccgagc tccaccgtgt ccgccaccag
    18961 ccccacctcg gcccgcccct cggccaccgc ctggacgatc tcgtggctga gccgctcctc
    19021 cagctccaca tccacctcgg gatgcgcggt gaggaaggca ctgagcgcct cggggaggaa
    19081 ctcggtgagg gccgcggtgt tggacaacag gcgcacctgg ccccgcaccc cacccgcgta
    19141 gccgccgagc tcaccgcgca ggttctccac ctgccgcagc acggcgcggg catgctgggc
    19201 cagcgcccgg cccgcaggcg tgggccgcac cccgcgccgc tcgcgctcca acagcgccac
    19261 acccagctcg tcctccaggc cacggatgcg cgcgctggcc gaggcgagcg cgaggtgggc
    19321 ccgctccgcc ccgtgggtga tgctgcccgt ctccaccacg aggaggaaca gccgcaggtc
    19381 catcaggtcc aagcccatca cgcctcctcg ccaggacagg cgatttcctc ctgccttcgt
    19441 ggcaagcgaa ggctgcccgc gtttcttcca cattgtccgg aggcggggac gtccgcaagc
    19501 tcacggcatg aacctgctct ccacgttccc ctggctcctc ggcgcgggcc tgctcgcggg
    19561 ggccatgaac gccgtggcgg gaggtggcac gttcgtcacc ctccccgccc tcgtcctggc
    19621 cggtgtgcct tcggtcgtcg cgaatgcatc cagcaccgtc gccctcttcc cgggaggact
    19681 cgccagcacc tgggcctatc gcgccgacct ctcgcctccg cgaggcgtgt cgctccgcgc
    19741 cctggtggtg gtgagtctgg ccgggggcct cgtgggctcg ctgctgctgg tgctcacccc
    19801 tcgggccgcc ttcgatcggc tcctgccctg gctgctcctc ctggccagcg gcgtgttcgc
    19861 gctcggggcc cggccgggcc tcatgcccag ctcacgggtc cgctcctccc ccgccgtgct
    19921 gctctcgctc caattcctgc tcgccatcta tggcggctac ttcggaggtg cggtcggcat
    19981 catgatgatg gcggtctgga gcctgctggg ccgctcggac ttgaaggtcc tcaaccccct
    20041 caaggcgctg ttggtgaccg ccacgaacac catcgccgtg ctctgcttcg tcgtgctggg
    20101 cgcggtgtcc tggcccgaga ccctcctcgt gctgggcgcc gcggtggtgg gcggctacgc
    20161 gggtgcgcgg ctcgcccggc ggatggactc ccggcacctg cggctcggcg tcaccgggtt
    20221 gtccctcctg ttgacgatcg cgtacttcgt ccgagccgga tgagcggtgc cgcgccagga
    20281 aaggcgctca ggccgccgag cgcagcgacc ccggccgcgc gacgagcttc tccagggcct
    20341 cggcggcgag ccggggcgag tcgagggcct ggagttgctg ggccacggcc cggacgcgct
    20401 ggtgcagcgc ggtgtcctgg agcagcgcgg cgagggcctt ctggatggcc tccttcgtcg
    20461 cctgcttcct gggcaggtgg taggcgagcc ccatctccgc cagccgcgcg ccgatgaggg
    20521 gctggtcccc gaacagcggg gtgatgagca tggggacgcc ctggcgcagg gcccggccgg
    20581 tggtgcccca tcctccgtgc gtcaccagcg cggagacgtg ggggagcacc tgatcatggg
    20641 ggacgaagga ctcgagccgc acgtgcgcgc ccagtccctc ggggatgtcc gcggcaccgg
    20701 ccgccgtcgc gagcaggggg accttcagtg gagccagggc ctcgagcgtg cgccggaaga
    20761 ggcctccgtc catgggcagg gtggtggtgc tcaccaggac cgtaccgggc gcgagcgtgt
    20821 ccacggggaa cggcgccgcc tggggacgcg gcaggctgta ggacatgggg cccacgcaca
    20881 gttgcccggg cccccggggc cccggggggt agaagccctc gtgcacggtg accaggtgca
    20941 gggtgtcgga catgatggtg tggaagaact cggacgggcc ccccttcctc ggaggcaacc
    21001 ccagttcctc ccggcagcgg gccaggggca gggccagtcc catgagcgag tcgaggagcc
    21061 ctcggggcag gtacttcatc atcgggttgg gcggcagcac catcttcccg tccgcgccga
    21121 acagcatcag gggattggga cccacgctcg cgaagggccg ccccgtgagc tccgccgcgt
    21181 accgggccgc cggggacatg aacgacacca cgccgtccac ccgctcggtc cggatgacgt
    21241 cctcccactc ccgcgccatc cgcacgatct cccccaccat gcctgcccgc ccccgcacga
    21301 cgtcgcgcac cacctgatgg acgggccgct gcttccggct cgcccgaagc tgcatcatgc
    21361 gctcgaacgg atccccgaac gtcctgccct cgcgcgactc tcctcccgcc gccaccacgc
    21421 cgtgcgtgaa cttccggggg gcgtagacca acgcccggtg tccccggcgg atcaacccct
    21481 ccacgatgct caacatcggc agggtgtgcc ccgcctcgcc atacgccaac accaggaacg
    21541 tcgcgctcat ggcccttccc tcgtgccttc cgtgcttccc tgaatccaga ttcagagttt
    21601 gatggccagt tataatgtgc tccggaaaaa gtacaatcac cggaagtccg gggggaactc
    21661 gttgaaaagc aaaacgccgg agcgcttgga gcgccccggc gtcggtcctt cggagactca
    21721 ggctcgaatc acagaccgcg gtactgctgc accagcgagt ccatgcgatc gttctgaccg
    21781 gtggagaagg tgttcatgca cgagtcgtcg gtgtagtcca tgaagttggt gatgggatcc
    21841 acgcctgcgg tggtgcaggt gtcgcggccc gtcggacaac cgaaggcggc ggaggactcg
    21901 gccgcggtgt cgctcacgta gtcacccgag ccggtgcagc cgccctggaa cgtgtggtac
    21961 aggcccagcc agtggccgac ctcgtgggtg gccgtgtcac cctcgttgta gggagccgcg
    22021 gtgccgccgg gcagcgagct gtagaggatg accacgccgt ccagactcgg ctgcgaggcg
    22081 tagctggagg ggaaggtcgc ccagcccagc aggccctggc ccatgttgtt ggagtagatg
    22141 ttcaggtcgg ccgcggtgcc ctggcgcagc gccgccttca tcttcttctc acaggcgcca
    22201 ccgctgcacg tgtaccagga ggagttggtg gtgcggtccg tggccttcag ggtgaacttg
    22261 aaaggcgtat tcgcgtaggc ggcgttgagc acggagatct ggctggcgat ggccgcgtcc
    22321 gagatgttgc cctgcgaggt gctggtgccg ttgttgatga cgtgccagta gacgttgatg
    22381 ttcaccgagc ccgcggcgcg cgcctgggcc cgcacacggc cggccagggc ctgctccacg
    22441 ctctgcttct cctctgcgct cagctcctgc gtcgcgcagc cacgcaccac ttgctgcgtc
    22501 acctcctccg cgggcgcctg ctccacctcg gtgcacccac cgagcgccag catcgaaccc
    22561 aggaccaccg cgaactttcc actcatcgag acaacgccac ggaacattcc agctcctcgg
    22621 gaaaagttgg aagtacttat atctcaagaa aa
//
