LOCUS       NZ_CP022098            20168 bp    DNA     circular CON 17-FEB-2024
DEFINITION  Cystobacter fuscus strain DSM 52655 chromosome, complete genome.
ACCESSION   NZ_CP022098
VERSION     NZ_CP022098.1
KEYWORDS    RefSeq.
SOURCE      Cystobacter fuscus
  ORGANISM  Cystobacter fuscus
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Cystobacter.
REFERENCE   1  (bases 1 to 12349744)
  AUTHORS   Rupp,O., Goesmann,A. and Sogaard-Andersen,L.
  TITLE     Sequencing and comparative analysis of myxobacterial genomes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12349744)
  AUTHORS   Bruckskotten,M., Treuner-Lange,A., Rupp,O., Goesmann,A. and
            Sogaard-Andersen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2017) Department of Ecophysiology, Max Planck
            Institute for Terrestrial Microbiology, Karl von Frisch Str. 10,
            Marburg, Hessen 35043, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 09-AUG-2016
            Assembly Method                   :: Celera Assembler v. 8.1
            Expected Final Version            :: yes
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/17/2024 10:04:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,093
            CDSs (total)                      :: 10,016
            Genes (coding)                    :: 9,906
            CDSs (with protein)               :: 9,906
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 26 of 110
            Pseudo Genes (incomplete)         :: 101 of 110
            Pseudo Genes (internal stop)      :: 1 of 110
            Pseudo Genes (multiple problems)  :: 17 of 110
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:24:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5459814
            Orig. end                         :: 5479982
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20168
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="microviridin"
                     /region_number="26"
                     /rules="(mvd or mvnA)"
                     /tool="antismash"
     cand_cluster    1..20168
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(mvd or mvnA)"
                     /kind="single"
                     /product="microviridin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20168
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10168](-)"
                     /cutoff="20000"
                     /detection_rule="(mvd or mvnA)"
                     /neighbourhood="10000"
                     /product="microviridin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10168)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(mvd or mvnA)"
                     /neighbourhood="10000"
                     /product="microviridin"
                     /protocluster_number="1"
     gene            1084..1485
                     /locus_tag="CYFUS_RS22240"
                     /old_locus_tag="CYFUS_004390"
     CDS             1084..1485
                     /EC_number="3.1.2.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002639452.1"
                     /locus_tag="CYFUS_RS22240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_004390"
                     /product="thioesterase family protein"
                     /protein_id="WP_095987049.1"
                     /sec_met_domain="4HBT_2 (E-value: 2.7e-20, bitscore: 72.2,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVEARIRVIYGDTDQMGVVYHANYFRYFEFARGEYFRARGGSYRD
                     VEREGLMLPVVEASIAYKSPARYDDVLLVHARVSELKRASLTFHYDVRREGAPETLLCT
                     GQTVHACVGRDGRPTRLPPVLVQLLQTAD"
     gene            1529..2494
                     /gene="glpX"
                     /locus_tag="CYFUS_RS22245"
                     /old_locus_tag="CYFUS_004391"
     CDS             1529..2494
                     /EC_number="3.1.3.11"
                     /GO_function="GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA]"
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /gene="glpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002639451.1"
                     /locus_tag="CYFUS_RS22245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_004391"
                     /product="class II fructose-bisphosphatase"
                     /protein_id="WP_095987050.1"
                     /transl_table=11
                     /translation="MDRNLAMEVVRVTEMAAIASARLMGRGGKNESDQAAVDAMRRAFD
                     ALQINGTVVIGEGERDEAPMLYIGEEVGRRHADDPSVDIALDPLEGTNLCAYGRPGAIA
                     VVAMADKGKLLNAPDTYMEKIAVGPRARGAIDLRRSPTENLRSIAERMKVYVADLTVII
                     LERERHVELIKEVRAAGARIRLIDDGDVAGAIATCFEDTGVDVLMGTGGAPEGVIAAAA
                     VRSVGGDMQGRLVPRNAEEVARAARMGITDISKIYSAEDLASGDVMFAATGVTTGDFLR
                     GVRFFGGGCETHSVVMRSKTGTVRFIQSRHKFDKKPGYNF"
     gene            2547..2972
                     /locus_tag="CYFUS_RS22250"
                     /old_locus_tag="CYFUS_004392"
     CDS             2547..2972
                     /NRPS_PKS="Domain: Polyketide_cyc2 (2-139). E-value:
                     6.7e-19. Score: 60.6. Matches aSDomain:
                     nrpspksdomains_CYFUS_RS22250_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630395.1"
                     /locus_tag="CYFUS_RS22250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_004392"
                     /product="SRPBCC family protein"
                     /protein_id="WP_095987051.1"
                     /transl_table=11
                     /translation="MAGASRTIVINAPPEKLFDVIAQYEKYPEFLSEVKKIRVLERKDN
                     TLKVQYEVDVIKTIRYTILVTEERPKRMSWTFVEGEVMKDNKGSWVLEPDGEGRTKATY
                     TVELALGPLVPKAIVNALTETSLPKMLESFKRRAEAT"
     aSDomain        2553..2963
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CYFUS_RS22250_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="6.70E-19"
                     /label="CYFUS_RS22250_Polyketide_cyc2.1"
                     /locus_tag="CYFUS_RS22250"
                     /protein_end="139"
                     /protein_start="2"
                     /score="60.6"
                     /tool="antismash"
                     /translation="GASRTIVINAPPEKLFDVIAQYEKYPEFLSEVKKIRVLERKDNTL
                     KVQYEVDVIKTIRYTILVTEERPKRMSWTFVEGEVMKDNKGSWVLEPDGEGRTKATYTV
                     ELALGPLVPKAIVNALTETSLPKMLESFKRRAE"
     misc_feature    complement(3249..3263)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.33"
                     /tool="antismash"
     misc_feature    complement(3250..3262)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.55"
                     /tool="antismash"
     misc_feature    complement(3333..3346)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.87"
                     /tool="antismash"
     gene            3340..3519
                     /locus_tag="CYFUS_RS22255"
                     /old_locus_tag="CYFUS_004393"
     CDS             3340..3519
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630396.1"
                     /locus_tag="CYFUS_RS22255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_004393"
                     /product="hypothetical protein"
                     /protein_id="WP_071902205.1"
                     /transl_table=11
                     /translation="MLDAFIIEEIKRRERNRDDRDRPVLEIPLPRPDERPRRRSDAEDD
                     EKPPRGVVIIDLLG"
     gene            complement(3550..4611)
                     /locus_tag="CYFUS_RS22260"
                     /old_locus_tag="CYFUS_004394"
     CDS             complement(3550..4611)
                     /EC_number="3.2.2.-"
                     /GO_function="GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630398.1"
                     /locus_tag="CYFUS_RS22260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_004394"
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_095987052.1"
                     /transl_table=11
                     /translation="MPPRRPTESPPDIYPRLRGRGALLGLAVGDALGSTLKGRRLIAPA
                     FPHLSDGVHRNMRGGGPFSLKPGQVGESGQMACCLAGGIRESGTYDTEAQMRRYLKWRP
                     HAVGMDDYTKEVLTEMAESTLPKANAAQRLWLKDGRKRALNGSLARTPPIGVFFSKDAS
                     MRAMASFADSMLTHFDPHCLLACATLNASIAHALHAGEKLTKEDLFKATLRELAVMSAQ
                     LGRTLSSFVKEVSAATADVREDLSVSNQSDPLLYWPELHMHRKLDHVRVAFRLAYWELW
                     HAPSFEAALVDVVNRGGDSDVNGAVTGALLGAFYGEDAIPALWRQAVLEALNFRAGPLW
                     TLYHPKDMVLLAG"
     gene            4697..5992
                     /gene="eno"
                     /locus_tag="CYFUS_RS22265"
                     /old_locus_tag="CYFUS_004395"
     CDS             4697..5992
                     /EC_number="4.2.1.11"
                     /GO_function="GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="eno"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630400.1"
                     /locus_tag="CYFUS_RS22265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_004395"
                     /product="phosphopyruvate hydratase"
                     /protein_id="WP_095987053.1"
                     /transl_table=11
                     /translation="MTEIAQIVAREVLDSRGNPTVEAEVLLAGGAKGRAAVPSGASTGE
                     HEALELRDGDKGRYLGKGVRKAVEHITEKIAPELVGMDAADQYAVDQQMIEMDGTPTKG
                     KLGANAILAVSMATARAAADAHGLPLYRYIGGSQARTLPVPLMNILNGGAHADTRVDVQ
                     EFMVVPAGAPSFSEGLRWGAEIFHALKKILKGRKLNTAVGDEGGYAPDLPANEEALKLI
                     MEAISAAGFKAGEQVFLAMDVAASEFFDKGSKKYKLKGEGKEFDASGLLDYYQQLVSRY
                     PIVSIEDGMAEDDWDGWKKITDVLGGKIQLVGDDLFVTNVERLSRGIEAGTANSILVKV
                     NQIGSLTETFDAVRMAHKAGFTSVMSHRSGETEDTTIADLAVALDCGQIKTGSASRSDR
                     IAKYNQLLRIEQELGAGARYAGMKSIKGLKAK"
     gene            6026..6817
                     /gene="surE"
                     /locus_tag="CYFUS_RS22270"
                     /old_locus_tag="CYFUS_004396"
     CDS             6026..6817
                     /EC_number="3.1.3.6"
                     /GO_function="GO:0008252 - nucleotidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="surE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630402.1"
                     /locus_tag="CYFUS_RS22270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_004396"
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="WP_198316692.1"
                     /transl_table=11
                     /translation="MAGTQQPRILVCNDDGYFSEGLRALVDAVSPLGEVWVVAPDREQS
                     AASHAISLWRPLRLTEIRERWFSVDGTPADSAYLAIHHLLKDDRPKIMVSGINHGANLA
                     DDVNYSGTVAAAREAALLGIPSIAFSLVSRAPFDFQHAARFARSLVAAALAQPQLPPRM
                     LLSVNVPSGEPRGYAVTRLGRHSYGYDVVEKEDPRGRKYYWIGGSTYAHEDLPGSDCNA
                     VHDERLISVTPLNFELTDTPMLKDLSGWSLEGFPGAGRGGD"
     gene            6820..7707
                     /locus_tag="CYFUS_RS22275"
                     /old_locus_tag="CYFUS_004397"
     CDS             6820..7707
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630404.1"
                     /locus_tag="CYFUS_RS22275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_004397"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_095987055.1"
                     /transl_table=11
                     /translation="MRGAAASPALLALFALLTASGCAVVPSAVRPSDTRSSAVPPIALA
                     ELHEPHPELELVSEPPVPSSRTHTVAPGETLYRIAVNHQLSVEQLAAANGIKDPRTLSV
                     GQELVIPGAPRPIPVATESSPPPARAPTTSSPTPSSRGPIVSSPSRRPAGRPPPQTPPK
                     PVPETKGTLDWPLRGVLYARFGKKGREPHDGIDLAVPVGSPVKTAQEGEVLYAGEQRGY
                     GLIVIVQHSEHLITLYAHNRDLRVRTGQKVRRGQVLATVGESGKTSGPQLHFEVRVDGK
                     PVDPLDYLGALPSS"
     gene            7810..8835
                     /locus_tag="CYFUS_RS22280"
                     /old_locus_tag="CYFUS_004398"
     CDS             7810..8835
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630406.1"
                     /locus_tag="CYFUS_RS22280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_004398"
                     /product="hypothetical protein"
                     /protein_id="WP_232537711.1"
                     /transl_table=11
                     /translation="MCRFPPLLLLLLLAPAVHARPASESPAPPAPEAETPAPMRLVLLP
                     LKADAEAREEAPGLTALMASRLAESPRLAVSTESDVQAVRTAGACADGSCEQEAARATK
                     ARYVVTGRLDAFGSRFLLTATLVDSESGRALLRPRAEVAAREALPRAAVSLADQILATL
                     VPDPNARATSPVPEEARPGQGSFLAGVRINNSLISNLSSFNPGGDVELGYQFHPEWVVF
                     GQLGLTFVTSTQTGTKGGLNVVPGVLGLRHYHGIENPLRPYWGLGLGVQLSFGEFGIFR
                     QTGPLPTVIGFVGLEYLFFNHLGVQLEASTNIAQATLGLADGGLGSGLNLDLNAGIVWH
                     F"
     gene            8852..9991
                     /locus_tag="CYFUS_RS22285"
                     /old_locus_tag="CYFUS_004399"
     CDS             8852..9991
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1272: TPR
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630408.1"
                     /locus_tag="CYFUS_RS22285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_004399"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_095987057.1"
                     /transl_table=11
                     /translation="MHPRWHVLSLLVLLLAGCEDGPPKPGPKERAEGYYIKGTTEYLQG
                     NFEQALASFASMKELSPDDPRLPAALGEVYLSMGKLNEALAQFELALQRDPKRSTNWSR
                     VGFIHAQLGHTEEAQSALRKALAIYPRDFNALEQLGELDLKRGEKDSAVKHFLLAADAS
                     PDAGKAPLVLRAAEVFIAAGRHAEALLMLGEWTGAKGVRDPSLLSALGDEQVRAGQLLP
                     AAESYREAARQSPRDPTLWELVGEIYTRLDKPGDALAAYRESLRVKDRAIIHVAIARIH
                     LGRGERETAEEELGKALETVSGSDVRELMELAELLSTLGRKPDALRILTNLSAEPDHAR
                     DVELQRRTAALARELKDEAVVRAACARLVGDGGTPKKCP"
     gene            complement(10001..10168)
                     /locus_tag="CYFUS_RS22290"
                     /old_locus_tag="CYFUS_004400"
     CDS             complement(10001..10168)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     microviridin: mvnA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     microviridin: mvd"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630410.1"
                     /locus_tag="CYFUS_RS22290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_004400"
                     /product="microviridin/marinostatin family tricyclic
                     proteinase inhibitor"
                     /protein_id="WP_095987058.1"
                     /sec_met_domain="mvnA (E-value: 1.5e-08, bitscore: 33.7,
                     seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="mvd (E-value: 1.5e-14, bitscore: 53.2,
                     seeds: 55, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQETKQKPFFARLLESQGSEPSENGQSATKKYPSDNDEDQTLKY
                     PSDQEDLGGA"
     gene            complement(10320..11024)
                     /locus_tag="CYFUS_RS22295"
                     /old_locus_tag="CYFUS_004401"
     CDS             complement(10320..11024)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002616329.1"
                     /locus_tag="CYFUS_RS22295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_004401"
                     /product="CHAP domain-containing protein"
                     /protein_id="WP_198316694.1"
                     /transl_table=11
                     /translation="MTCRPLLLACLLGVFFAPPVLGAPRAPAKPAAVKKQQPPAASSTV
                     AKKSTKSTPAKTKRKVVPLSRGRRVAQRAAGLVGTSLSAHRVPDDCSGLVRLAYRSVGV
                     ELLSHGTRPGENAASAMYRRAQTKGALHRKAPQPGDIVFFRETYDRNRDGLRNDGVTHV
                     GVIESVARDGTIVFVHRGGKGVGRARMNLRHAGHQGMGGRVLNDYIRRAEQGERARLTS
                     ELFVGYASSTRL"
     gene            complement(11203..13647)
                     /locus_tag="CYFUS_RS22300"
                     /old_locus_tag="CYFUS_004402"
     CDS             complement(11203..13647)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630414.1"
                     /locus_tag="CYFUS_RS22300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_004402"
                     /product="ABC transporter permease"
                     /protein_id="WP_095987060.1"
                     /transl_table=11
                     /translation="MRLSKWWEDVARDLRFAARMLRKSPGFTAVAVLCLAFGIGANAAI
                     FSVVDSVLLRPLPYRDPERLVRLYETQPARDPDWRGSVSWPNYQDWAAQLRSFSGIAAY
                     EMQGRNLTSPEGAERLKAVAATANLFQVLGIVPKLGRGFSADEDKPGAAPVVVMSERLW
                     RRRFSANPALLGQTLSLDGRPHTVIGILPDTVRFPAGSQAELWLPHVPTEGRVDNRGSH
                     YLGVIARLAPGMTPQRANTELRQVAQRIEEAYPAQQTGRGATAVALTETVVGKVRPALL
                     ILQGAVLLVLLIACANVANLLLARAAARQQEVTVRFALGASRGRIVQQMLVESLLLSLL
                     GAVLGWLLAAWGLGALSPLVRDSLPLAGELTLQGRVFGFLLLVAAGSAVLFGLTPALQA
                     TRGELSAVLAQPGTKTSASRSQHTFRNGLVVAEIALSLVLLVGAGLLLRGFVNLLGTKT
                     GLNEQGVLTAHLPIAGNKYAPEQLTERLLKPVLEKARALPGVRSAALISLLPIQDAWTN
                     GDYTVEGEPPPPPGKEFFAEHRVTSPGIFQSLGIPLLAGRDFAEEDGLRREQVIIINQT
                     LARRHFEGRDAVGRRLMLGGDSAEIIGVVGDVRQAGLDQKPLPEVHLPYNHPLSQRWLF
                     QEATLVLKTSVEPLSLTSALRDAVRGVDSDQPISEVATMEEVISRSVAGRRLNLALLGT
                     FALIALVLATAGLYGVISYVVAQRTREIGIRMALGAQPGDVVRLVMHQGVVLATLGVGI
                     GVLVALSLSRFVESLLYGVSARDPLTFGVLSVLLGGVALLATWLPARRASRVDPIIAMR
                     GE"
     gene            complement(13717..14580)
                     /locus_tag="CYFUS_RS22305"
                     /old_locus_tag="CYFUS_004403"
     CDS             complement(13717..14580)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS22305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_004403"
                     /product="hypothetical protein"
                     /protein_id="WP_095987061.1"
                     /transl_table=11
                     /translation="MEILVISDDAVEEQISRSLEASPSLPWRISRSKVSDFLRASGATF
                     SDEDGLFHHQQPAAGGSTSAQPIILNRVVEISDQTLKALGGENSLLARGLVTSALDHVL
                     RGYKKVIGTPGVCSPVGHLVPLVSQWKLIGKKVPGLRTPEYKYGYGPEPIDSAPFARPI
                     WKSPFDFYSWKVSDAPPAVHWDSFVVNRPEGTPVLLYFFGKAWDAQFLAPGQALSEELK
                     GRLRELIPALQETFGAFSGESLMFADGPVLTFASFSHYFSAASRQARFQSVLLEGLAAE
                     LPLARG"
     gene            14746..14985
                     /locus_tag="CYFUS_RS50825"
     CDS             14746..14985
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS50825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157758591.1"
                     /transl_table=11
                     /translation="MTTWPLRSTSKSNTEPALSRQTNRASEGLLMTRPSMRLTTSPAWN
                     GQNPAGVDWVATTPCVLDSSTSEAEPAWIWARSV"
     gene            complement(15098..16297)
                     /locus_tag="CYFUS_RS22315"
                     /old_locus_tag="CYFUS_004404"
     CDS             complement(15098..16297)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS22315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_004404"
                     /product="HEXXH motif-containing putative peptide
                     modification protein"
                     /protein_id="WP_157758592.1"
                     /transl_table=11
                     /translation="MQIIYSLTAGGSCPPLIDNQVEHFVQKLKFQFEDLLWLARLSSPE
                     TARAASAAYEALSARERYAFFLSPAVFSEMFRQQWAGKTPELRGLIDLCIGESALETSA
                     QYPGEARERWNPLFSKASHAGGIPGNAYVAPLLGGSVTVDLSSPFCKRSDMTSPVFFGD
                     FVPFTEEEKERVLSKLSAAFAEIEATAPIFARIIRNYTRVACVRKREGAPPASEQVSDE
                     IGAIRLLNVHSPDYTHESLMDDLIHESVHNLLSTYEYLEHPFQIVGGESDGDARPVSPW
                     SMRPIRVLPFLHAVFVYFAILHYTLKRMERGELSAEQQRLAVKRRNRYASGFLMPGKLS
                     DYVKPFSNVDPRTLHAMDQMQQIIRRRFSPLPESRPENVAVAPAGGAQYQPPVQKGAAP
                     "
     misc_feature    complement(16318..16331)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.32"
                     /tool="antismash"
     gene            complement(16376..16648)
                     /locus_tag="CYFUS_RS22320"
                     /old_locus_tag="CYFUS_004405"
     CDS             complement(16376..16648)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS22320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_004405"
                     /product="hypothetical protein"
                     /protein_id="WP_095987063.1"
                     /transl_table=11
                     /translation="MKKLNCAAAIASLAVAAGPIAVDASVDSDKTLTLSAEQAEASFAL
                     EIEGFNELIAAKSSQQQQQQQQQQNRNQSDSAGVQFAPSDSGFAV"
     misc_feature    complement(16738..16751)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.0"
                     /tool="antismash"
     misc_feature    16745..16758
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.78"
                     /tool="antismash"
     misc_feature    complement(16747..16760)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.54"
                     /tool="antismash"
     misc_feature    complement(16750..16766)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.32"
                     /tool="antismash"
     misc_feature    complement(16797..16817)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.24"
                     /tool="antismash"
     misc_feature    16828..16842
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.44"
                     /tool="antismash"
     gene            16987..17730
                     /locus_tag="CYFUS_RS22325"
                     /old_locus_tag="CYFUS_004406"
     CDS             16987..17730
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630424.1"
                     /locus_tag="CYFUS_RS22325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_004406"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_095987064.1"
                     /transl_table=11
                     /translation="MTSGAGQTRARDEQPREAPAKELLRLEGLTKVFETDEMETHALSE
                     VNLSVGQGEWVSIVGPSGSGKSSLLAVLGLLDTASRGRYLLDGQQVLELSPAQRALVRN
                     RHIGFIFQSFNLIGDLSVYENVELPLTYRDMVADERQARVERALERVGMSHRARHMPGQ
                     ISGGQQQRVAVARAVAGEPLLLLADEPTGNLDSKNGAQVMQLLTELHQGGATLIMVTHD
                     PNQARLGTRQVGLFDGRIVQDERLR"
     gene            complement(17763..18425)
                     /gene="lexA"
                     /locus_tag="CYFUS_RS22330"
                     /old_locus_tag="CYFUS_004407"
     CDS             complement(17763..18425)
                     /EC_number="3.4.21.88"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="lexA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630426.1"
                     /locus_tag="CYFUS_RS22330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_004407"
                     /product="transcriptional repressor LexA"
                     /protein_id="WP_095987065.1"
                     /transl_table=11
                     /translation="MEELTERQREILAFIVKETESRGFPPTIREIGEEMDIRSTNGVND
                     HLKALERKGYLNRGEQQSRSLVPTKRARMLLGLGVKKESGMVEVPLLGKVAAGAPLLAQ
                     ENAEDSVRIDSFLLGGNGREVFALRVKGQSMIDDGIFDGDYLFVRKTAQAQPGDIVVAL
                     IEDEATVKRYYPEGERIRFQPANATMQPIYVNRADFRSTMILGQVVGVYRKLPGGKN"
     misc_feature    19290..19304
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
ORIGIN
        1 ctcggccagc gccaccagat cacccaccgc cttgtccagg cggaacatcg tgtcctgcat
       61 ctcccaggag ttcgggccgt actggtggta gacgcgatcc gtggcgctga agctcaccgc
      121 gagcagatcc ggcacctcgt ccttgcccag cccctcgccg gcgatggcgg ccccggcggc
      181 gcgcaccacc agatcgagcg acaacgggga gatggcgaag gcgctgtagg cctggggacc
      241 cggctgcgtg agccctccgg tgagcgggtg ggggaagacg cgcccgagcc cgtagtactc
      301 gccctcgtag ggacgatcat cctcgcccag gtactcggtg cgcttgcgca ccggctccca
      361 cgtcttgccg aaccaggtgg tgggcgggtt ggccgcgttg aaggccttga gccagccggg
      421 cagctccttc gtgtaccagg tgcccgtgac gaacttcccc acggtctcgt cgaaccagta
      481 cgcctggccg agccggcccg cgagcggaat ggccgagcgc gccttgcccg acagggccac
      541 cgccttgccc tgctcgttcg tggccagccg cagccggtcc gcgagcgtct ccgccaggag
      601 gttggccgga ctcacgtcgt cctcggacag gggcgcctcc agcaccgggt gctgcgcgtc
      661 cgggaagacg cgcgcgggct tgcccgtggc ccgatcgatg acgcggttgt ccacgatgcc
      721 gtggcgccac gggttggcgc cggtggcgag cgtcgcgtgg cccggcgcgg tgcgcggctt
      781 ggcgtagtcg tagcgcgcgt acgggtagaa ggcccccgag tcgatcagct tgcccaggcc
      841 gccctggagc cggggccggg tgcgcagcag cagatccgag cccatcgcgt ccacggtgat
      901 gaagagcgtc aaccggggcg gcttcgccca ggcgggcagc gcgaggagca acagcagcag
      961 ggggagggga gcgcgggggc ggaacatggg ctcgcatcct ccacgcctcg tgctcagaag
     1021 caaccaactc ccggggctca tgcttcccgg ttggacactg ccttgttacg gtcggcggga
     1081 ctcatggtcg aggcacgaat ccgagtcatc tacggcgata cggaccagat gggtgtcgtg
     1141 tatcacgcca attatttccg ctacttcgag ttcgcccggg gcgagtactt ccgcgcgcgg
     1201 ggtggcagct accgggacgt ggaacgcgag ggactgatgc tgcccgtggt ggaagcttcc
     1261 atcgcctaca agtcccccgc gcgctatgac gacgtgctgc tggtgcatgc ccgggtgagt
     1321 gagctcaagc gcgcatcgtt gaccttccat tatgacgtcc ggcgcgaggg cgctcccgag
     1381 accctgctgt gcaccggcca gaccgtccat gcctgcgtgg gccgcgacgg caggcccacg
     1441 cgcctgccgc ccgtgctcgt gcagttgttg caaacggcgg attgagtctc cacctcttca
     1501 catcccgttt cctcaggagg aacccacaat ggatcgcaac ctggccatgg aggtcgtgcg
     1561 cgtcaccgag atggcggcca tcgcctccgc gcggctgatg ggccgcggcg gcaagaacga
     1621 gtcggatcag gccgccgtgg acgccatgcg ccgcgccttc gatgccctgc agatcaacgg
     1681 cacggtggtc atcggcgagg gcgagcgcga cgaggccccc atgctctaca tcggcgagga
     1741 ggtgggccgg cgccacgcgg atgatccctc cgtggacatc gcgttggatc ccctcgaggg
     1801 caccaacctg tgcgcctacg gccgcccggg cgccatcgcc gtggtggcca tggccgacaa
     1861 gggcaagctg ctcaacgcgc cggacacgta catggagaag atcgccgtgg ggccgcgcgc
     1921 ccggggcgcc atcgatctgc gccgcagccc cacggagaac ctgcgctcca tcgccgagcg
     1981 catgaaggtc tacgtggccg acctcaccgt catcatcctc gagcgtgagc gacacgtgga
     2041 gctcatcaag gaggtgcggg ccgcgggcgc gcgcatccgc ctcatcgatg acggggacgt
     2101 ggcgggcgcc atcgccacct gcttcgagga cacgggcgtg gacgtgctca tgggcaccgg
     2161 cggcgcgccc gagggcgtca tcgccgccgc ggccgtgcgc tcggtgggcg gggacatgca
     2221 ggggcggctc gtgccgcgca acgccgagga ggtcgcccgc gccgcgcgca tgggcatcac
     2281 cgacatctcc aagatctact ccgccgagga tctggccagc ggcgacgtga tgttcgccgc
     2341 cacgggcgtt accactggcg acttcctgcg cggtgtgcgc ttcttcggcg gtgggtgcga
     2401 gacgcactcg gtggtcatgc gcagcaagac cggtacggtg cgcttcatcc agtcacgtca
     2461 caagttcgac aagaagccgg gctacaactt ctaggcacgc cctcaacctc tacagagaac
     2521 ctcttcaccc ctcggagaca cacaccatgg ctggcgcctc tcgcaccatc gtcatcaacg
     2581 ccccccccga gaagctcttc gacgtcatcg cccagtacga gaagtacccg gagttcctct
     2641 ccgaggtgaa gaagatccgc gtcctcgagc gcaaggacaa cacgctcaag gttcagtacg
     2701 aggtggatgt catcaagacc atccgctaca ccatcctcgt caccgaggag cgccccaagc
     2761 gcatgtcctg gaccttcgtc gagggtgagg tgatgaagga caacaagggc agctgggtgc
     2821 tcgagcccga cggcgagggt cgcaccaagg ccacctacac ggtggagctc gccctggggc
     2881 cgctcgtccc caaggcgatc gtcaacgccc tcaccgagac gtccctgccc aagatgctgg
     2941 agtccttcaa gcgccgcgcc gaggccacct agcacctcgc ccaggtcctt ccctcggtcc
     3001 tccaaggagc gggcgggaga ccgggccccc ttcccgtcgg tcctgtcatt tcagggagag
     3061 cggaacggag ccccaggcat cgcttgcggg cccgtacaag ttcattacaa tccacttcac
     3121 gttctgaatg tccgcgggtg gacgacccgc ggaccgagga acgttccacc gggtccggct
     3181 gtcgggtgga ggacggacaa gcgggcttgc cagcccagga gtcctccaat cgtgaatggg
     3241 gcccttactt tgcaaattga agcacccgtg gcggcgaatc cctcctgaag gagtgacgag
     3301 catccaccgg gtacgtaggc cgagggagaa accgaaccca tgctcgacgc cttcatcatc
     3361 gaggaaatca agcgccggga acggaaccgg gatgaccggg atcgtcccgt gctggaaatc
     3421 cccctgcctc ggcccgatga gcgcccccgg cgccgctcgg acgccgagga tgacgagaag
     3481 ccgccacgcg gcgtcgtcat catcgatctg cttggctgag tctcggggcg ggtggcccgg
     3541 ggtggccctt cagcccgcca gcagcaccat gtccttcggg tggtagaggg tccacagcgg
     3601 cccggccctg aagttgagtg cctccaggac ggcctggcgc cagagcgcgg gaatggcgtc
     3661 ctctccgtag aaagcgccca gcagcgctcc ggtgacggcg ccgttcacgt ccgagtctcc
     3721 tccccggttg acgacgtcga ccagcgccgc ctcgaacgag ggcgcgtgcc acagctccca
     3781 gtaggccagg cggaacgcca cgcgcacatg gtccagcttg cggtgcatgt gcagctccgg
     3841 ccagtacagc agcggatcgc tctggttgga gaccgacagg tcctcccgga cgtcggcggt
     3901 ggcggcggag acttccttga cgaagctgct gagggtgcgc ccgagctgcg cgctcatcac
     3961 ggccagctcg cgcagcgtgg ccttgaacag gtcctccttg gtcagcttct cccccgcgtg
     4021 gagcgcatgg gcgatggacg cgttgagggt ggcgcacgcg agcagacagt gcggatcgaa
     4081 gtgcgtgagc atgctgtcgg cgaacgaggc catggcacgc atcgaggcgt ccttggagaa
     4141 gaacacgccg atgggggggg tgcgcgccag gctgccgttg agcgcccgct tgcgcccatc
     4201 cttcagccac aggcgctgcg cggcgttcgc cttgggcagg gtcgactcgg ccatctcggt
     4261 caacacttcc ttggtgtagt cgtccatgcc cacggcgtgc gggcgccact tcaggtagcg
     4321 gcgcatctgg gcttccgtgt cgtaggtgcc ggattcccgg atgcctccgg ccaggcagca
     4381 agccatctgg ccgctctcgc ccacctgtcc cggcttgagg gagaacgggc ctcctccgcg
     4441 catgttccgg tggactccgt cggacaggtg cgggaaggcc ggggcgatca gccgccggcc
     4501 cttcagcgtg ctgcccagtg cgtctccgac ggcgaggccc aggagcgcgc cccggcctcg
     4561 caggcgtggg tagatgtcgg gaggggactc ggtggggcgg cgcgggggca tggcgggaga
     4621 ggggtggggg tgaagtgccc gcgaagtgta gcagtctgct tgcgagcctg ggggacgtcc
     4681 tctagaaccc cgcgccatga ccgagattgc tcaaatcgtg gcgcgtgaag tactcgattc
     4741 ccgcggaaac cccaccgtgg aggccgaggt gttgctggcg ggtggggcca agggccgtgc
     4801 ggcggtgccc tccggggcct ccaccggcga gcacgaggcg ctggagctgc gcgacggcga
     4861 caagggccgc tacctgggca agggcgtgcg caaggccgtc gagcacatca ccgagaagat
     4921 cgcccccgag ctggtgggca tggacgcggc ggatcagtac gccgtggacc agcagatgat
     4981 cgagatggac ggcacgccca ccaagggcaa gctgggcgcc aacgccatcc tcgcggtgtc
     5041 catggccacg gcgcgcgccg cggcggatgc ccacggtctg cccctctacc gctacatcgg
     5101 cggctcccag gcgcgcaccc tgccggtgcc gctgatgaac atcctcaacg gcggcgccca
     5161 cgccgacacc cgcgtggacg tgcaggagtt catggtggtg cccgccggcg ctccctcctt
     5221 ctccgagggc ctgcgctggg gcgcggagat cttccacgcg ctcaagaaga tcctcaaggg
     5281 ccgcaagctc aacaccgccg tgggcgacga gggcggctat gccccggacc tgccggccaa
     5341 cgaggaggcg ctcaagctca tcatggaggc catctccgcc gcgggcttca aggccggtga
     5401 gcaggtgttc ctcgccatgg acgtggcggc gagcgagttc ttcgacaagg gctccaagaa
     5461 gtacaagctc aagggcgagg gcaaggagtt cgacgcctcg ggcctgctcg actactacca
     5521 gcagctcgtg tcgcgctacc ccatcgtctc catcgaggac ggcatggcgg aggacgactg
     5581 ggacggctgg aagaagatca ccgacgtgct cggcgggaag atccagctcg tgggagatga
     5641 tctcttcgtc accaacgtgg agcgcctgag ccgcggcatc gaggcgggca ccgccaactc
     5701 catcctggtg aaggtcaacc agatcggcag cctcacggag accttcgacg cggtgcgcat
     5761 ggcccacaag gccggcttca cctcggtgat gagccaccgc tcgggcgaga ccgaggacac
     5821 caccatcgcg gacctggccg tcgcgctcga ttgtggacag atcaagacgg gctcggcctc
     5881 gcgctccgac cgcatcgcca agtacaacca gctcctgcgc atcgagcagg aactgggcgc
     5941 gggcgcccgg tacgcgggca tgaagtccat caagggcctg aaggccaagt aaggccaggc
     6001 agacaacctg aagaaaggcg gagaagtggc cggcacgcag caaccccgca tcctggtgtg
     6061 taacgatgac ggctacttct ccgaggggct cagggccctg gtggacgcgg tcagtcccct
     6121 gggcgaggtg tgggtggtgg cgcccgatcg cgagcagagc gcggcctcgc acgccatctc
     6181 cctctggcgc cccctgcgcc tcaccgagat ccgcgagcgc tggttctccg tggatggtac
     6241 ccccgcggac agcgcttatc tggcgatcca tcacctcctg aaggatgatc gcccgaagat
     6301 catggtgtcc ggcatcaacc acggggccaa cctggccgac gacgtcaact actcgggaac
     6361 ggtggcggcc gcccgcgagg cggccctgct gggcatcccc tccatcgcct tcagcctggt
     6421 gtcgcgcgcc ccgttcgact tccagcacgc ggcgcgcttc gcccgctcgc tggtggcggc
     6481 ggcgctcgcc cagccccagt tgcctccccg gatgctgctg agcgtcaacg tgccctcggg
     6541 cgagccccgg ggctacgccg tcacccgcct gggccggcac tcgtacggct atgacgtggt
     6601 ggagaaggaa gacccgcgcg gccgcaagta ctactggatc ggcggcagca cctacgcgca
     6661 cgaggacctg cccggtagcg actgcaacgc cgtgcacgac gagcgcctca tctccgtcac
     6721 gccgctcaac ttcgagctca ccgacacccc catgctgaag gatctctcgg gctggagcct
     6781 cgagggcttc ccgggcgcgg gcaggggagg ggattgaggt tgcggggcgc ggcggccagt
     6841 ccggcactgc tcgcgctgtt cgcgctcctg acggcctccg gctgtgccgt ggtgccctcc
     6901 gccgtgcgcc cctccgacac gcgctcctcc gccgtgcccc cgatcgcgct cgccgagctg
     6961 cacgagcccc acccggagct ggagctcgtc tccgagcccc ccgtgccctc ctcgcgcacc
     7021 cacacggtgg ccccgggcga gacgctctac cgcatcgccg tcaaccacca actgagcgtg
     7081 gagcagctcg ccgcggccaa tggcatcaag gatccgcgca cgctctccgt gggccaggag
     7141 ctggtgattc ccggtgcccc ccggcccatt cccgtggcca ccgagtcctc gccgccgccc
     7201 gcgcgcgcgc ccaccacgtc cagccccacg ccgtcgtccc ggggacccat cgtctcgtcg
     7261 ccgtcacgcc gcccggcggg ccggcccccg ccccagacgc ctcccaagcc cgtcccggag
     7321 acgaagggca cgctggattg gcccctgcgc ggtgtcctct acgcgcgctt cggcaagaag
     7381 ggccgcgagc cccatgacgg catcgacctg gcggtccccg tgggctctcc ggtgaagacc
     7441 gcccaggagg gcgaggtgct gtacgcgggg gaacagcgcg gctacggcct catcgtcatc
     7501 gtccagcact ccgagcacct catcacgctc tacgcgcaca accgcgacct gcgcgtgcgc
     7561 accggccaga aggtgcgtcg cgggcaggtg ctcgccacgg tgggcgagtc gggcaagacg
     7621 agcggccccc agctgcactt cgaggtgcgc gtggatggca agccggtgga tccgctcgac
     7681 tacctgggcg cgctgccctc ctcgtgagtc ccatgtgagt cccatgtgcg tccgatgatg
     7741 gaccgaacgg gcggagcgcc tcctcgctcc gtgccccacc cgggagcatc tggcactaga
     7801 gtgtcgcgcg tgtgccgttt cccgccgctg ctgctcctgc tcctgctcgc cccggccgtc
     7861 catgcccggc ccgcctccga gtccccggcg cctcccgccc ccgaggcgga gactcccgcg
     7921 ccgatgcgcc tcgtgctcct gcccctcaag gccgacgcgg aggcacgcga ggaagcccct
     7981 ggcctgacgg cgctcatggc gagccggctc gccgagtccc cccgcctcgc ggtgtccacc
     8041 gagtcggatg tccaggccgt gcgcaccgcg ggcgcctgcg cggatggctc gtgcgagcag
     8101 gaagccgcgc gcgccaccaa ggcccgctac gtcgtcaccg gccggctcga tgccttcggc
     8161 tcgcgcttcc tgctcaccgc caccctggtg gactcggaga gcgggcgtgc cctgctccgg
     8221 ccccgcgccg aggtggccgc ccgcgaggcc ctgcctcgcg ccgccgtgtc cctggcggat
     8281 cagatcctcg ccacgctcgt gccggacccc aacgcccgcg ccacgtcgcc cgtgcccgag
     8341 gaagcccgcc cgggccaggg ctcgttcctc gccggcgtgc gcatcaacaa cagcctcatc
     8401 tccaacctct cctcgttcaa ccccggcggc gacgtggagc tcggctacca gttccatccc
     8461 gagtgggtgg tgttcggtca gttgggcctc accttcgtca cctccacgca gacgggcacc
     8521 aagggcggcc tcaacgtggt gcccggcgtg ctcgggctgc gccactacca cggcatcgag
     8581 aatcccctgc gtccgtactg gggcctggga ttgggcgtgc aactgtcctt cggcgagttc
     8641 ggcatcttcc ggcagacggg cccgctgccc accgtcatcg gcttcgtggg cctcgagtac
     8701 ctcttcttca atcacctcgg cgtgcagctc gaggcctcca ccaacatcgc ccaggcgacg
     8761 ctcggcctgg cggacggggg gctgggcagt ggcctcaacc tcgatctcaa cgccggcatc
     8821 gtctggcact tctgagcctg gagcccactc catgcatccg cgctggcacg tcctgtccct
     8881 gctcgtcctc ctcctcgcgg gctgcgagga cggccctccc aagcccggcc ccaaggagcg
     8941 ggcggagggc tactacatca agggcaccac cgagtacctc cagggcaact tcgagcaggc
     9001 cctggcctcc ttcgcctcca tgaaggagct gtccccggat gacccccgcc tgcccgccgc
     9061 cctgggcgag gtctacctgt ccatgggcaa gctcaacgag gcgctcgccc agttcgagct
     9121 cgccctccag cgcgatccca agcgctccac caactggagc cgggtgggct tcatccacgc
     9181 ccagctcggc cacaccgagg aggcccagag cgccctgcgc aaggccctgg ccatctaccc
     9241 ccgggacttc aatgccctgg agcagctcgg ggagttggat ctcaagcgcg gcgagaagga
     9301 ctccgccgtg aagcacttcc tgctcgcggc cgacgcgagc cccgacgccg gcaaggcccc
     9361 gctcgtgctg cgcgccgccg aggtgttcat cgccgcgggg cgccacgccg aggccctgtt
     9421 gatgctcggg gagtggacgg gcgccaaggg cgtgagggat ccgtcgctgc tctcggcgct
     9481 gggagacgag caggtgcgcg ccggacaact gctccccgcg gccgagtcct accgcgaggc
     9541 ggcgcgccag tcgccgaggg atcccacgct gtgggagctc gtgggggaga tctacacgcg
     9601 cctggacaag ccgggcgatg cgctcgcggc ctaccgcgag tccctgcggg tgaaggatcg
     9661 ggccatcatc cacgtggcca tcgcgcgcat ccacctgggc cgcggcgagc gcgagacggc
     9721 ggaggaggaa ctgggcaagg cgctcgagac ggtgtcgggc tcggacgtgc gcgagctcat
     9781 ggagctggcc gagctgctct cgacgctcgg gcgcaagccg gatgcgctgc gcatcctcac
     9841 caacctgagc gccgagccgg accatgcccg ggacgtggag ctgcagcggc gcaccgcggc
     9901 gctcgcccgg gagttgaagg acgaggccgt ggtgcgcgcc gcgtgcgcgc gcctcgtggg
     9961 ggatgggggc acccccaaga agtgcccctg agggcgcgac tcaggcccct cccagatcct
    10021 cctgatccga ggggtacttc agcgtctgat cctcgtcgtt gtccgagggg tacttcttcg
    10081 tcgcgctctg tccattctcg gagggctcgc ttccctggct ctcgagcaac cgcgcgaaga
    10141 agggtttctg cttcgtttcc tgcttcatgg cctgcctccg tggggtaggc gggaaccgac
    10201 tcgcccgcct gggttgatga aaatgcaacc cgaggtgtcg cggggaaagt cgccaaccag
    10261 cctcctcctg ctctcccgct cggacaacgg tccgatgaac cgggggctca tccacgcgcc
    10321 tacagccggg tagacgacgc gtacccgacg aacagctcgc tcgtgaggcg tgcgcgctcg
    10381 ccctgctcgg cccggcggat gtagtcgttg aggacgcgtc cccccatgcc ctggtgcccg
    10441 gcatggcgca ggttcatccg cgcccgtccc acgcccttgc ctccgcggtg cacgaagacg
    10501 atggttccat cgcgggccac cgattcgatg acgcccacgt gcgtcacccc gtcgttgcgc
    10561 aggccatccc ggttccggtc atacgtctcg cggaagaaga cgatgtcgcc gggctggggc
    10621 gccttgcggt gcagggcgcc cttggtctgg gcgcgccggt acatggcgct cgccgcgttc
    10681 tctcccgggc gggtgccgtg cgagagcaac tccacgccca cggaccgata ggcgagccgc
    10741 acgagccccg agcaatcatc cgggacgcgg tgggcggaga gcgatgtgcc caccaggccc
    10801 gcggcccgct gggccacccg ccggccccgg gagagcggca cgaccttgcg cttcgtcttc
    10861 gcgggcgtgg acttcgtgga cttcttcgcg acggtgctgg acgcggcggg cggctgttgc
    10921 ttcttcaccg ccgccggctt cgcgggcgca cggggcgccc ccagcacggg aggcgcgaag
    10981 aacacgccca gcaggcaggc cagcaggagc ggacgacacg tcatggcgtt ctggacgggc
    11041 cctcgcttcg gcgattcaat tccctcgcgg cgcgtcccgg cgagtcccgc ccacctgtcc
    11101 atcaggcaac agggcgtggc ctccttctcc tctcacgtcc aaggtaggca cgatccgccc
    11161 gtcacgcgag aaacggaccg tggcctcgtg cgccaggacg gctcactcgc cgcgcatggc
    11221 gatgatcgga tccacccgcg acgcgcgccg ggcgggcagc cacgtggcca gcagcgccac
    11281 gccaccgagc agcaccgaga gcacgccgaa ggtgagcgga tcccgggcgc tcacgccata
    11341 gagcagactc tccacgaacc gcgacaggct gagcgccacg agcaccccga tgcccacccc
    11401 gagcgtcgcc aacaccacgc cctggtgcat caccaaccgc accacgtcgc ccggctgggc
    11461 acccagcgcc atccggatgc cgatctcccg cgtgcgctgg gcgacgacat acgagatgac
    11521 gccgtagagg cccgcggtgg cgagcaccag cgcgatgagg gcgaaggtcc ccagcagcgc
    11581 caggttcaac cgccgccccg cgaccgaacg cgagatgacc tcctccatgg tcgccacttc
    11641 ggagatcggc tgatccgaat ccacgccgcg caccgcgtcg cgcagggcgg acgtcaggct
    11701 gagcggctcc accgatgtct tcagcaccag cgttgcttcc tggaacaacc accgctggga
    11761 gaggggatgg ttgtagggca ggtgcacctc gggcaggggc ttttgatcca accccgcctg
    11821 ccgcacgtcg cccaccacgc cgatgatctc cgcggaatcg cctcccagca tcaaccgccg
    11881 ccccaccgcg tcccggccct cgaaatgccg ccgcgccagc gtctggttga tgatgatcac
    11941 ctgctcgcgg cgcaggccat cctcctcggc gaagtcccgc ccggcgagca acgggatgcc
    12001 cagggactgg aagatgcccg gactggtgac ccggtgctcg gcgaagaact ccttgccggg
    12061 tggcggaggc ggctctcctt ccaccgtgta gtccccattg gtccaggcgt cctggatggg
    12121 cagcagcgag atgagggccg cggacctcac cccgggaagg gcacgcgctt tctcgagcac
    12181 cggcttgagc agacgctcgg tgagctgctc cggcgcgtac ttgttgcccg cgatgggcag
    12241 gtgggcggtg agcaccccct gctcgttcag cccggtcttg gtgccgagca ggttcacgaa
    12301 gcctcgcagc aacagccccg cccccacgag cagcacgagc gagagcgcga tctccgccac
    12361 cacgagcccg ttgcggaagg tgtgctggga gcgcgaggcg gacgtcttgg tgcccggttg
    12421 ggcgagcacg gcgctcagct cgccgcgcgt ggcctgcagc gcgggcgtca gcccgaagag
    12481 gaccgcgctg cccgcggcca ccagcagcag gaagccgaag acgcggccct ggagcgtcag
    12541 ctccccggcg agcgggagcg agtcacgcac cagggggctc agcgcgccca gtccccaggc
    12601 ggccagcagc caccccagca ccgcgcccag cagcgacagc agcagactct ccacgagcat
    12661 ctgttgcacg atgcggcccc ggctcgcccc gagggcgaag cgcaccgtca cctcctgctg
    12721 cctcgcggcc gcgcgcgcca gcagcaggtt ggccacgttg gcgcacgcga tgagcagcac
    12781 gagcagcacc gcgccctgga ggatgagcag cgcgggccgc accttgccca ccaccgtctc
    12841 cgtcaacgcc acggccgtgg cgccgcgccc cgtctgctgc gcgggatacg cctcctcgat
    12901 gcgctgggcc acctggcgca gctcggtgtt ggcccgttgc ggcgtcatgc ccggggccag
    12961 ccgcgcgatg acccccaggt agtgcgagcc ccggttgtcc acccggccct ccgtgggcac
    13021 gtggggcagc cacagctccg cctgcgagcc cgccggaaag cgcaccgtgt ccgggaggat
    13081 gccgatgacc gtgtgcggcc ggccatccag cgacagcgtc tggcccagga gcgccggatt
    13141 ggcgctgaag cggcggcgcc acagccgctc gctcatcacc accacgggcg cggcgcccgg
    13201 cttgtcctcg tccgcggaga agccccggcc gagcttgggg acgatgccca gcacctggaa
    13261 gaggttggcc gtggccgcca ccgccttgag ccgctccgcg ccctccgggc tcgtcaggtt
    13321 gcggccctgc atctcatagg cggcgatgcc gctgaagctc cgcagctgcg ccgcccagtc
    13381 ctggtagttg ggccacgaca ccgagcccct ccagtcggga tccctcgccg gttgggtctc
    13441 gtagagccgc acgagccgct cgggatcgcg gtagggcagc gggcgcagga gcaccgagtc
    13501 caccacgctg aagatggccg cgttggcgcc aatgccgaag gccaggcaca gcaccgccac
    13561 ggcggtgaag cctgggctct tgcggagcat gcgcgcggcg aagcgcagat cgcgcgcgac
    13621 gtcctcccac cacttgctca aacgcacccg tcgcacctca tcccgctgga ctctagcaaa
    13681 tccccggacg ccccccgagc gacgggtgcc cgccgctcac ccgcgcgcca gcggcagctc
    13741 cgcggcgagt ccttccagca gcacgctctg gaatcgggcc tggcgggagg ccgcgctgaa
    13801 gtaatgcgag aaggaggcga aggtgagcac cgggccgtcg gcgaacatca ggctctcacc
    13861 cgagaacgcg ccaaacgtct cctggagcgc gggaatcagc tcgcgcagcc gtcccttcaa
    13921 ctcctccgac agggcctggc ccggggccag gaattgcgcg tcccacgcct tgccgaagaa
    13981 gtacagcagc accggcgtgc cctcgggcct gttcaccacg aacgagtccc agtgcaccgc
    14041 gggaggcgcg tccgacacct tccacgagta gaaatcgaag gggctcttcc agatcggccg
    14101 cgcgaagggg gcggagtcga tgggctcggg cccgtagccg tacttgtact cgggcgtgcg
    14161 cagcccgggg accttcttcc cgatgagctt ccactggctg accagcggca ccaggtggcc
    14221 caccggcgag cacacgcccg gagtcccgat gaccttcttg tacccgcgca gcacgtgatc
    14281 gagcgcgctg gtgacgagcc cccgggcgag cagcgagttc tctcccccca gggccttcag
    14341 ggtttgatcc gagatctcca ccacccgatt gaggatgatg ggctgggcgg acgtggagcc
    14401 cccggcggcg ggctgctggt ggtggaacag cccgtcctcg tcgctgaacg tggcgccact
    14461 ggcgcgcagg aagtcactga ccttcgagcg ggagatgcgc cagggaaggc tcgggctcgc
    14521 ctccagtgaa cgggaaatct gctcttcgac ggcatcgtcc gagatgacaa gaatctccac
    14581 aaaggctcca gcaggctggc gggaacgtgc ccgcgcggtg gctcctggcc agctcccgat
    14641 cttcccgggt gcttagcgca tcgtccccgg agggggcggc ggggcggggg gctcggggtg
    14701 gggggcaggt cgagcccggg gaagtccgag gggccggccc ggaaggtgac gacctggccg
    14761 ttgcgcagca cctcgaagtc gaacaccgag ccggcgctct cccgccagac gaacagggca
    14821 tcggagggcc tgctgatgac gcggccatcg atgcgcctca ccacatcccc cgcctggaac
    14881 ggccagaacc ccgccggcgt cgactgggtg gcgaccacgc cttgcgtcct ggactcgagc
    14941 accagcgagg ccgagcccgc ctggatctgg gcccggtccg tctgagcggt cattcgggtg
    15001 ttcatctgat ggcctccttg gggctcaccg gacggcttcg cggggccgct cggagcgacc
    15061 gcgagcacga aaaaacccac gaacagcgcg gaggtcgtca cggggcggct cccttctgga
    15121 cgggcggttg gtattgcgcg ccacccgccg gcgccacggc cacgttctcc gggcgggact
    15181 cgggcagggg cgagaacctc cggcggatga tctgctgcat ctgatccatc gcatgcagcg
    15241 tgcgcggatc cacgttcgag aagggcttca cgtagtcgct cagcttgccc ggcatcagga
    15301 agcccgaggc gtagcgattg cgccgcttca cggccaggcg ctgctgctcg gcggagagct
    15361 ccccgcgctc catccgcttg agcgtgtagt ggaggatggc gaaatagacg aacaccgcgt
    15421 gcaggaaggg aagcacccgg atggggcgca tcgaccaggg cgacacgggg cgcgcatcac
    15481 cgtccgactc gcctccgacg atctggaacg gatgctccag atactcgtac gtcgacagca
    15541 ggttgtgcac cgactcgtgg atcaagtcat ccatcaagct ctcgtgcgtg tagtccggac
    15601 tgtgcacgtt gagcaggcgg atcgcgccaa tctcgtcgga gacctgctcg gaggcgggcg
    15661 gcgccccctc gcgcttgcgc acgcatgcga cgcgcgtgta gttgcggatg atgcgcgcga
    15721 agatgggcgc ggtggcctcg atctcggcga aggccgcgga aagcttgctc agcacccgtt
    15781 ccttctcctc ctcggtgaag ggcacgaagt cgccaaagaa cacggggctc gtcatgtccg
    15841 agcgcttgca gaaggggctc gacaggtcca ccgtcaccga accacccagc agtggcgcca
    15901 cataggcgtt gcccggaatg cccccggcgt gactcgcctt ggagaacagg ggattccaac
    15961 gctcacgggc ctcgcccggg tactgggcgg acgtctcgag ggcgctctcc ccgatgcaca
    16021 gatcgatcag gccccggagc tccggagtct tccccgccca ctgctgacgg aacatctccg
    16081 agaagaccgc tggcgacagg aagaaggcgt accgctcccg cgcgctcaac gcctcatagg
    16141 cggcgctcgc cgcccgcgct gtctccggag aggacagccg cgcgagccac aggagatcct
    16201 cgaactggaa cttgagcttc tggacgaagt gctcgacctg attgtcaatg aggggtgggc
    16261 aggaaccacc agcggtcaat gaatagatga tctgcaacac aggagggcac cccgcggttg
    16321 gagtgaaaaa aaaggcctcg ggcattcggg cccggggcct ttccctacag cggaatcaga
    16381 ccgcgaagcc gctgtcgctg ggggcgaact ggacgcccgc gctgtcgctc tggttgcggt
    16441 tctgctgctg ctgctgctgc tgctgctgct ggctgctctt cgccgcgatg agctcgttga
    16501 aaccctcgat ctccaacgcg aacgaagcct cggcctgctc ggcgctcaga gtcagggtct
    16561 tgtcgctgtc gacggacgcg tcgacggcga tgggaccagc ggcaacagcg agcgaagcga
    16621 tggcagcggc gcagttgagc ttcttcatga ggcactccct tgtcgttggt agagggcgct
    16681 acgaaaccgc ctggcgcgtc tgctgttcag ggggctgcgt cacagccgcg caaacggtga
    16741 gaaaagttat agaaacaaaa ctactgccag tcaacagcac ccggcacttt gcgtcatgat
    16801 tgtcaaatca accagaatgg gactcgggga ctacccggtc cgcgggggcc gtcggcgcct
    16861 ggacttccct tccgggcgca tgtggttttc ccggacgtgg catcccaccg ctccctcttc
    16921 tgtttcgagc gttcagcgtt tcgggggagt atccgggagg cgtctgatct gccgtgggag
    16981 gtggcgatga cgagcggagc ggggcaaacg cgggcgcgcg acgagcagcc gcgagaggcg
    17041 ccggcgaagg agctgttgcg gctcgagggc cttaccaagg tcttcgagac cgacgagatg
    17101 gagacgcacg cgctctccga ggtgaacctc tcggtgggcc agggcgagtg ggtgtccatc
    17161 gtggggccct cgggctcggg caagtcgagc ctgctggcgg tgctggggct gttggacacg
    17221 gcctcccggg ggcgctacct gctggatggg cagcaggtgt tggagctgtc cccggcgcag
    17281 cgggcgctgg tgcgcaaccg gcacatcggc ttcatcttcc agagcttcaa cctgattggt
    17341 gacctgtccg tctacgagaa cgtggagctg ccgctgacct atcgcgacat ggtggcggac
    17401 gagcgccagg cccgggtgga gcgggccctg gagcgcgtgg gcatgagcca ccgggcgcgg
    17461 cacatgcccg ggcagatctc cggtggccag cagcagcgcg tggccgtggc gcgcgccgtg
    17521 gcgggcgagc ccctcctgct cctggcggac gagcccaccg gcaacctcga ctcgaagaat
    17581 ggagcgcagg tgatgcaact gctcaccgag ctgcaccagg gcggcgccac cctgatcatg
    17641 gtgacccatg atccgaatca ggcgcggctt ggtacgcgtc aggtgggtct cttcgatggc
    17701 cgcatcgtcc aggacgagcg cctgcgctga gcggcctcga cgaggagggg ccccgtggcg
    17761 cctcagttct tgccgcccgg cagcttgcgg tacacgccca ccacctggcc gaggatcatg
    17821 gtggagcgga agtccgcccg gttcacgtag atgggctgca tggtggcgtt ggccggctgg
    17881 aagcggatgc gctcgccctc ggggtagtag cgcttgaccg tggcctcgtc ctcgatgagc
    17941 gccaccacga tgtcgccggg ctgcgcctgc gccgtcttgc gcacgaagag gtagtccccg
    18001 tcgaagatgc cgtcgtcgat catcgattgg cccttgaccc ggagcgcgaa cacctcgcgc
    18061 ccgttgcccc ccaacaggaa gctgtcgatg cggaccgagt cctccgcgtt ctcctgggcg
    18121 agcaggggcg cgccggcggc caccttgccg agcaggggga cctccaccat ccccgactcc
    18181 ttcttcacgc ccagtcccag cagcatgcgc gcccgcttgg tgggcaccag cgagcggctc
    18241 tgctgctcgc cccggttgag gtagcccttg cgctcgagcg ccttgaggtg atcattcacc
    18301 ccgttggtcg agcggatgtc catctcctcg ccgatctccc ggatggtcgg cgggaagccc
    18361 cgcgactcgg tctccttcac gatgaaggcg aggatctccc gttgacgttc ggtcagctct
    18421 tccatgatgc ccggctccct cggctggtgg gcaacccacc tgcgaaacag gctttcagtc
    18481 ccagcatgct ccctgaacat acgtatagag tcaatgcgtt caaggggctt gcagccctcc
    18541 gaggacggat gctgaggggg caccccggct gggcgtagac ttggccaacc gtgtccgaca
    18601 cccgacatac cctgctgttg gtcgatgacg agccggatgt catcgatctc ctccagcgca
    18661 tgttccacaa gcgctaccag gtgctctcgg cctcctcggg ccgcgaggcc ctggagctgc
    18721 tcaggcgcca tcccgtggac gtgctcatca ccgaccagcg catgccggag atgacgggca
    18781 tcgagctggt gacggccgcg cgcgccgagg gcctcgacgt cacggcgctg ctgctcaccg
    18841 gctacaccaa ccccgaggac atcatcgcgg ccatcaaccg ggggcaggtc taccgctaca
    18901 tcaccaagcc gtgggacctg aacgatctcg tcttcaccgt gaagaacgcg gtggactaca
    18961 cccagctgcg gcgcgacaag gagcggctct tgcgccagct gcaccagcgg gtggaggcgc
    19021 tcgacgtgct ctacgcggtg acgcgcgcga gcgccggaga gccgctcgac tacgacgcca
    19081 tcatcgatcg ggtgctcgtg gcggtgtcgc gcgtgctgcc atacgactgt ggcgcggccc
    19141 tcatcgcgct ggggtgggat cgtacggcca ccctgcgcct gcgctgccag gggctggccg
    19201 tgggcgagca ggccctgctc ggcgtcaagg agtccatgct gggcgcctgg agcacgcgct
    19261 cggggctgat gttgtccgag gaccgcgtca tcacccacgt cgagggcacc acgtccccgg
    19321 acaccgccgc cccggtcgtc tggggcagcc agctcaccgt ggccctcacc gccgagggcc
    19381 gtccggtggg gctcttgtcg ctcttctccc agcgcgcgca cgcctactcc gaggaggatg
    19441 gcgcgctgct cgacaccctg gccaaccaga cggccgccgc catccaggcc ctgcgcgcct
    19501 ccgaggaggc gtcgcgccag cgcatcgagc gcatggtgca gtccatggcc gatggcgtgc
    19561 tgctcaccga cgagaagaac gaggtggtgg tgctcaaccc cgccgcgcgc cgcctgctgc
    19621 ggctcgagga gggcgccctc caggacgccg gagcgcggct gcgcgagcgg ctcgggttcg
    19681 atcccttcga gctggtgcac ggctgggagg cgggcagcgc ccaggtgttg cgcgaggagc
    19741 tcacgctgga tgcgcgcacc atccacacca cggtgacacc ggtgcacgac gcgcggggcg
    19801 tgctgcgcgg cgtgtgcgtg gtgctgcgcg acgtcaccga gcagaagcag ctcgaggagc
    19861 gcaaggacga gttcgtccac atggtgagcc acgagctgcg cacgcccctc acctccatct
    19921 ccggctcgtt ggacctggtg ctcaacttcc tcaccacgga catgaacgag aagcagcggc
    19981 gctacctcct gctcgcgcgc gactcgacgg agaagctcaa cgccatcgtg gatgatctgc
    20041 tggacctggc caagttcgcc aagggccggc tgcggatgaa cttcgagtgg acgcacgtgg
    20101 acgagctggt gcgccgcgcg gtggagaagt acggcccggc cttccaggcg cgcggcgtga
    20161 cgatgacc
//
