LOCUS       NZ_CP022098            20963 bp    DNA     circular CON 17-FEB-2024
DEFINITION  Cystobacter fuscus strain DSM 52655 chromosome, complete genome.
ACCESSION   NZ_CP022098
VERSION     NZ_CP022098.1
KEYWORDS    RefSeq.
SOURCE      Cystobacter fuscus
  ORGANISM  Cystobacter fuscus
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Cystobacter.
REFERENCE   1  (bases 1 to 12349744)
  AUTHORS   Rupp,O., Goesmann,A. and Sogaard-Andersen,L.
  TITLE     Sequencing and comparative analysis of myxobacterial genomes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12349744)
  AUTHORS   Bruckskotten,M., Treuner-Lange,A., Rupp,O., Goesmann,A. and
            Sogaard-Andersen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2017) Department of Ecophysiology, Max Planck
            Institute for Terrestrial Microbiology, Karl von Frisch Str. 10,
            Marburg, Hessen 35043, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 09-AUG-2016
            Assembly Method                   :: Celera Assembler v. 8.1
            Expected Final Version            :: yes
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/17/2024 10:04:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,093
            CDSs (total)                      :: 10,016
            Genes (coding)                    :: 9,906
            CDSs (with protein)               :: 9,906
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 26 of 110
            Pseudo Genes (incomplete)         :: 101 of 110
            Pseudo Genes (internal stop)      :: 1 of 110
            Pseudo Genes (multiple problems)  :: 17 of 110
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:24:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4268094
            Orig. end                         :: 4289057
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20963
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="21"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20963
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20963
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10963](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10963
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(154..168)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.08"
                     /tool="antismash"
     gene            327..1583
                     /gene="glyA"
                     /locus_tag="CYFUS_RS17570"
                     /old_locus_tag="CYFUS_003474"
     CDS             327..1583
                     /EC_number="2.1.2.1"
                     /GO_function="GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0070905 - serine binding [Evidence IEA]"
                     /GO_process="GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (82-374). E-value:
                     5.7e-12. Score: 37.3. Matches aSDomain:
                     nrpspksdomains_CYFUS_RS17570_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="glyA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002639902.1"
                     /locus_tag="CYFUS_RS17570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003474"
                     /product="serine hydroxymethyltransferase"
                     /protein_id="WP_071898458.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9e-10, bitscore:
                     37.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENTRLLAEVDPEIARAIQDETRRQEEGLELIASENFVSPAVMEA
                     AGSVLTNKYAEGYPGKRYYGGCEVVDVAETLAISRARELFGAEYANVQAHSGSQANMGA
                     YMALMKPGDTLLALDLNSGGHLTHGSAFNFSGKLYKAVHYGLTRDTETIDYAQAAALAK
                     EHKPRVVVVGASAYPRIIDFAKFREIADSVGAALMVDMAHIAGLVAAGLHPSPVPLADI
                     VTSTTHKTLRGPRGGLVLSKEPYAKTLNSQIFPGIQGGPLMHVIAAKAVAFREALSPEF
                     KAYQKQIVANAQALAEALQKGGLRLCSGGTDNHLMLVDLRPKKLVGKVAEEVLGKAGIT
                     VNKNMIPFDPEKPTVTSGVRIGTPALTTRGMKEAEMATVGALVVEALDNASDEQRLASI
                     RGRIQEFTRSFPLYASRLK"
     aSDomain        573..1448
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CYFUS_RS17570_Aminotran_1_2.1"
                     /evalue="5.70E-12"
                     /label="CYFUS_RS17570_Aminotran_1_2.1"
                     /locus_tag="CYFUS_RS17570"
                     /protein_end="374"
                     /protein_start="82"
                     /score="37.3"
                     /tool="antismash"
                     /translation="ELFGAEYANVQAHSGSQANMGAYMALMKPGDTLLALDLNSGGHLT
                     HGSAFNFSGKLYKAVHYGLTRDTETIDYAQAAALAKEHKPRVVVVGASAYPRIIDFAKF
                     REIADSVGAALMVDMAHIAGLVAAGLHPSPVPLADIVTSTTHKTLRGPRGGLVLSKEPY
                     AKTLNSQIFPGIQGGPLMHVIAAKAVAFREALSPEFKAYQKQIVANAQALAEALQKGGL
                     RLCSGGTDNHLMLVDLRPKKLVGKVAEEVLGKAGITVNKNMIPFDPEKPTVTSGVRIGT
                     PALTTRGMKEA"
     gene            1592..2089
                     /gene="nrdR"
                     /locus_tag="CYFUS_RS17575"
                     /old_locus_tag="CYFUS_003475"
     CDS             1592..2089
                     /GO_function="GO:0140110 - transcription regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nrdR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630219.1"
                     /locus_tag="CYFUS_RS17575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003475"
                     /product="transcriptional regulator NrdR"
                     /protein_id="WP_095986277.1"
                     /transl_table=11
                     /translation="MRCPFCQDPENKVIDSRESHEGSVIRRRRECLQCKRRFTTYERVE
                     EIYPLIVKKDGRRETFDRDKLLAGLQKACEKRPVSADQLEETLVAVERLLQGVGEKEVP
                     SSVIGEEVMRRLHALDEVAYVRFASVYRSFRDITEFMAELKDLLSDRTREHKPPRPPDK
                     DG"
     gene            2096..3271
                     /gene="ribD"
                     /locus_tag="CYFUS_RS17580"
                     /old_locus_tag="CYFUS_003476"
     CDS             2096..3271
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="ribD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1240: riboflavin biosynthesis protein RibD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630218.1"
                     /locus_tag="CYFUS_RS17580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003476"
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
                     RibD"
                     /protein_id="WP_095986278.1"
                     /transl_table=11
                     /translation="MRLLTRARLQAGRAPRAKRTADFDRAVAEFFMRLALEEAAKGLGR
                     TSPNPVVGAVLVKGGRIIARGYHRRAGTAHAEVVALEAAGGKARGADLYTTLEPCDHYG
                     RTPPCSQALIDAGVRRVITASSDPNPKVNGKGVARLRRAGVEVLTGVLKDEADQLNRPF
                     FKAMRTGLPFVTLKAAVTLDGKLATATGDSRWVTGEEARAWVHRLRDRVDVILVGATTA
                     RRDNPQLTTRLPESAGKDPVRVVVDSHLRLPSTLQVFTQRSPARTVVATLEDPSARKAK
                     RFLATGTDVWQLPEKQGRVDLEALMRRLAREGLNHVLVEGGAEMYGSFLREELADELLL
                     FVAPKLIGGEGLSWSGSLGVKQMARALTVGALSMEQVGTDLLLRARLDPAR"
     gene            complement(3291..4712)
                     /locus_tag="CYFUS_RS17585"
                     /old_locus_tag="CYFUS_003477"
     CDS             complement(3291..4712)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="CYFUS_RS17585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003477"
                     /product="cytochrome P450"
                     /protein_id="WP_269770246.1"
                     /sec_met_domain="p450 (E-value: 1.3e-90, bitscore: 303.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSETTSQTSSDRSLPPRVSSLPLVGCLPRLIANPLSFMEQAQREH
                     GDIFSMDLGFTQVIGLCHPRYVHHVLVEHAHKYSKGGPMWDSMRTFMGNALPMSEGAFW
                     KRQRRMIQPSFHHQRVSLMTDTMVEAIDECLLEWDLAALEGKPFDVSVALSRVTMTVLV
                     RTLFGSGLDKDDAEKVAQAFSFILEYFIAGMVTHSLPEWMPVPGRQRYRESIKMIDEIM
                     RRLIERGREQASGEDNLLSLLLQAVDGESGERMTNEQLRDEALGFFIAGYDTTAAGMTW
                     VLHALTQHPEVTDKVRVELDAVVGTRRPGFADLMRMPYTRNVLQEALRIHSPSVWLPRL
                     SVVEDEIDGYRIPPGVMMVIFTRLIHRHPGIWDDPLTFDPDRFTPERSEGRHKLAWLPF
                     GSGQRQCIAKEFSLLEGMLIMARIVSRYELSSVPGRLPQERVSTNLRTKDGMWLNLRPR
                     LPQAQVPRIQLSGTA"
     misc_feature    4841..4855
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.73"
                     /tool="antismash"
     gene            5177..6427
                     /locus_tag="CYFUS_RS17590"
                     /old_locus_tag="CYFUS_003478"
     CDS             5177..6427
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630216.1"
                     /locus_tag="CYFUS_RS17590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003478"
                     /product="cytochrome P450"
                     /protein_id="WP_232537628.1"
                     /sec_met_domain="p450 (E-value: 6.6e-33, bitscore: 113.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSPTNSDSSLQGLSLNPISPENLVNPIPLYKALRESEPVYWSDT
                     VHAWLVTRYADVVACFRDPRLSANRTNFYEQQLQGMGGDVAGEFLKSARLQMTMRDGAD
                     HIRVRRQASPGFTPQGLDTYRPAIRQFMGMLLDRVQEWGHMDVVKEISYQLPPLVIAEF
                     LNIPAQDRERFQAWARPLADFANPKPGVNMQDVAREASRVTVEMNAYLAERIEERRHHP
                     GSDMLSLMIHAQELGRMTEDDLAANTLLILTAGHLTTTDQISNGVYDLLSHPEQRQKLQ
                     NDRTLLRSAVEEMLRFSPAVPFAFRVAAQDFTLHGKDIRKGDTVFLGLAAANRDPSVFT
                     DPETFDITRDSVQQKHLTFAFGAHHCLGAGLARREMEISIEMLLDRLPQVRLDETKKPQ
                     HKVGLVFRSFNSLHLDW"
     misc_feature    5276..5278
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6669..8489
                     /locus_tag="CYFUS_RS17595"
                     /old_locus_tag="CYFUS_003479"
     CDS             6669..8489
                     /GO_component="GO:0098561 - methyl accepting chemotaxis
                     protein complex [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012245.4"
                     /locus_tag="CYFUS_RS17595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003479"
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_095986279.1"
                     /transl_table=11
                     /translation="MPADKQITQTINKIFLIRQFFGSIILSPATTYLINNLSGLTDDEM
                     SKTTKFTMPIVFGLFSLIVPYLVMNYTIRRAFSTLRGDHEGSKIERLLKIPGQLEALMI
                     LCAILGSTFYITVPILFHKKSLAPIPWVLSTTLLVLMLNFINERLIYERILRPFAIEEF
                     HKHPKAVIRGTGFFWPRMKWYLPYAFGVFVASTLMLSTTIIAKQVIITFDELNQVMQTD
                     AAHIGEHISRVVDLVVQRAAIPLSLMGGYLLAISSIAAWLLARRQELGALSVQEAIEGL
                     ASGSPKLPDWISTDEIGDLAGSTSRAFEKLSAFSLSLGESANSLRGSAERLGSSASEQS
                     TVLTRQAAALQETQVTAQEIKQTSELASQKAENVLQQTTRANQISTEAVAAVRTSLEEI
                     QEVGQQVAKMASSIQSLEKKTQQIASITRTVKDLADQSNMLALNAAIEAVRSGEHGKGF
                     GVVAREIRALADQSIRATNNVNSILLDIGNAMRSTAAMTTKGYEKVELSLKGIKGFEGS
                     IQQLSSIVRDNADSIRQITAAVTQQNVGISQIFQAVNDLNNMMEQTMGQMQTSEEASTV
                     VQSVADQVSGLVTSYGWKEAAERARQNRTT"
     gene            8537..9979
                     /locus_tag="CYFUS_RS17600"
                     /old_locus_tag="CYFUS_003480"
     CDS             8537..9979
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1246: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.4"
                     /locus_tag="CYFUS_RS17600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003480"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_157758497.1"
                     /transl_table=11
                     /translation="MSKGTFSSASRRFGGRHAVVIGGSMAGMAASRALASHFERVTLIE
                     RDRLPEKPELRKGLPQEQQAHGILAKAVEILEGYFPGLWQQMVAAGSNVLDMSDVALYR
                     GGIWQARATPGLTLYIQTRTLLDSVIRSRVREISNLQILDECEVVKPVVTSNRVAVWGV
                     EVRRRKQEATEILEADLVVDATGRGSRMPRWLEELGLPRVEETHVRIDVGYASRKVRKL
                     QGVTTNWKTLSIFPTAPRETRLGALAPVEGDTWLVTLAGALGDHAPGDEAGFLEFARAL
                     PQPHVYEMLRRCEPVSPVAAHKFPSSMRRHYERMTGIPEGLVVLGDAVCSLNPIYGQGM
                     TLSVLAASLLEECLSEQAPRAMMGFGRRFQAKLSRMHDMPWTMGAGEDLVYPSVEGPRP
                     LWWKAMQGASGHLQSLAAYDPVVTTAFAKVMHMTGSPLELAHPSMLLRMVRGPQGEGPG
                     ESPVMQFPEGSAPPSKTVASVA"
     gene            10001..10963
                     /locus_tag="CYFUS_RS17605"
                     /old_locus_tag="CYFUS_003481"
     CDS             10001..10963
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="CYFUS_RS17605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003481"
                     /product="hypothetical protein"
                     /protein_id="WP_095986281.1"
                     /sec_met_domain="T1TS (E-value: 8.9e-80, bitscore: 268.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTIALPPLRLPFPQKLNPHNHQAWPHTVEWVKRFNLLPEKAIPY
                     FRAQDYHWLSAYAFPEADLEQLILINDCMTAFYLFDKHWDDAPPDALESMQAPLLDALW
                     GRPPGDAPEGPLENAMRDMRRRMMKYSTDAWMTRFCESLEAYFKACVWEAKNKSNSQVP
                     DVASYIRMREATGAVQPSFELAGVLGLVQIPPSVLEEPIIKRLNQLANHEITLFNDIIS
                     LEKEMRVGDMHNLVFIIQKQNEKNGTECSLEGAMKQAAKMHDDEVLEFLELEAKVPSWG
                     EPLDTEVRRYIDVLRCWMRANMDWSLMSTRYKTPEAPAA"
     misc_feature    complement(10002..10016)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.37"
                     /tool="antismash"
     misc_feature    complement(10003..10018)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.52"
                     /tool="antismash"
     gene            11069..11716
                     /locus_tag="CYFUS_RS17610"
                     /old_locus_tag="CYFUS_003482"
     CDS             11069..11716
                     /EC_number="2.5.1.9"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630212.1"
                     /locus_tag="CYFUS_RS17610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003482"
                     /product="riboflavin synthase"
                     /protein_id="WP_095986282.1"
                     /transl_table=11
                     /translation="MFTGLIQDIGVVERVIPGGMTDLWIRTALGARDFALGESIAVDGA
                     CLTVVERAGDSFRVQAAPETLRRTTLGARQPGSRVNLERALALGDRLGGHLVAGHVDAV
                     SEVLETRAEGGSWVMVFRLPAELAPFFIEKGSVAIDGISLTVNTVGTDRFSVQLIPETQ
                     ERTTLRSRGVGERVNLEGDMIGKYVARLVSLRQGPGGGGLSEAVLKAAGFGG"
     gene            11743..12939
                     /gene="ribB"
                     /locus_tag="CYFUS_RS17615"
                     /old_locus_tag="CYFUS_003483"
     CDS             11743..12939
                     /EC_number="4.1.99.12"
                     /GO_function="GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ribB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630211.1"
                     /locus_tag="CYFUS_RS17615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003483"
                     /product="3,4-dihydroxy-2-butanone-4-phosphate synthase"
                     /protein_id="WP_095986283.1"
                     /transl_table=11
                     /translation="MARGRQHESDSITLVEKALAEIRKGRMVILTDDEDRENEGDLVMA
                     AEKVTPQDINFMATHGRGLICLALDEERIRRLNLPLMVQDNTSSFQTAFTVSIEAAQGV
                     STGISAADRAHTIQVAVAPNARPSDLARPGHIFPLRARQGGVLVRTGQTEGSVDLARMA
                     GLRPSGVICEIMNPDGTMSRRPDLVKFARKHQMVLLSVADIIRYRLERERLVRRLEETT
                     LERRGQGSFRAYTYGSDVDSAVHVAVVKGELSGREPVLTRVHRTCLVGDLLGSAGCECG
                     VQLERAFQAIHEAGRGVIVFLQGDSARKNRLRCTHVSNEELVPGHKDQTRLREFGVGAQ
                     ILKDLGLTRLRLLTNNPKKIVGLESYSLEVVEQVPLIPAAPATRRVAARRPPRGRQAS"
     gene            13007..13498
                     /gene="ribE"
                     /locus_tag="CYFUS_RS17620"
                     /old_locus_tag="CYFUS_003484"
     CDS             13007..13498
                     /EC_number="2.5.1.78"
                     /GO_component="GO:0009349 - riboflavin synthase complex
                     [Evidence IEA]"
                     /GO_function="GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="ribE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020478482.1"
                     /locus_tag="CYFUS_RS17620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003484"
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="WP_002630210.1"
                     /transl_table=11
                     /translation="MPRYIEGDFLPPKGRFAICVARFNAFITEELVKGALDTLVRHGVA
                     DGDIDVFRCPGTYELPALTRRVSETRSYVGIITLGAVIRGGTPHFDYVSGECTKGIGQV
                     AFTSQAAVTFGVLTCDTVEQAIDRAGVKAGNKGSEAAAACIEMVNLHAKLATLTDGKRS
                     "
     gene            13502..13921
                     /gene="nusB"
                     /locus_tag="CYFUS_RS17625"
                     /old_locus_tag="CYFUS_003485"
     CDS             13502..13921
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015350756.1"
                     /locus_tag="CYFUS_RS17625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003485"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_002630209.1"
                     /transl_table=11
                     /translation="MGARRTARERALQALYQMEMTPGSIHDALEAAWAAAEVTNKEPEA
                     VKFARELTEGVMAHRAEIDRLIEQHSHNWRLDRMSRIDRNVLRLGVFELKYRPDIPKKV
                     SLNEAVELGKNFGTEESSAFVNGLLDRVAVALGKQ"
     gene            13918..14406
                     /locus_tag="CYFUS_RS17630"
                     /old_locus_tag="CYFUS_003486"
     CDS             13918..14406
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630208.1"
                     /locus_tag="CYFUS_RS17630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003486"
                     /product="M17 family peptidase N-terminal domain-containing
                     protein"
                     /protein_id="WP_095986284.1"
                     /transl_table=11
                     /translation="MNVSAHELGLGGLDALADVDALCLFVGEDDRPLPGTAGYVDWRLC
                     GTLSRVLQSGFFVGAQDDSLLLPTDGRFSIPRVFVMGLGRRRGLEPSSLGEALASAGKV
                     LTRARVESVALEVPGQDALDESVRLSALQEHFLPAFRGRKVAVLADKELARRLSGRKG"
     misc_feature    complement(14453..14467)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.31"
                     /tool="antismash"
     gene            14458..14832
                     /locus_tag="CYFUS_RS17635"
                     /old_locus_tag="CYFUS_003487"
     CDS             14458..14832
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002616935.1"
                     /locus_tag="CYFUS_RS17635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003487"
                     /product="response regulator"
                     /protein_id="WP_095986285.1"
                     /transl_table=11
                     /translation="MTSKILIVEDSKASRELISATVESIPGLEAIATSSGLEALKLLPQ
                     HAFALIITDINMPDINGLELIRFVKTNPTLRDTPLFIVTTEGREKDRDRGLALGAAEYL
                     VKPFSPQSLEGLVRRYLKLA"
     gene            14829..17117
                     /locus_tag="CYFUS_RS17640"
                     /old_locus_tag="CYFUS_003488"
     CDS             14829..17117
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006935 - chemotaxis [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011554745.1"
                     /locus_tag="CYFUS_RS17640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003488"
                     /product="chemotaxis protein CheA"
                     /protein_id="WP_095986286.1"
                     /transl_table=11
                     /translation="MNSAGKALAEFVAEGTEILESLGKELLVLDQQRGVEPEPDIINGI
                     FRAAHSLKGLAALFGQERIARLAHQSEDLLDRLRLGRLSLDDQVLDLLIESLDVLQALL
                     AEAAREESSDALNERVKELGERLANLGTASAAADEDPLDRLELDPQVRSVFTEYEEHRL
                     RENVRRGVALFRIRAAFDLSDFDTGLTELNVRLKPLGEVVSTLPSSEPGGLSGIAFDLI
                     FGSRVSEAELAAKLQGTPAQLFALTVRPSAAALVPVGSAPETPAAPLPLALPPAEAPAA
                     KKTTRRKPRASKTGAGSSTSAEDVAPADAPLVKASSLRAVEPVVPALPASDTSSLPVVR
                     TLTEEPVAPRGPKAESESARSLTQTVRVDISRLDALMNTVGELLLIKANLQRMAESARV
                     DAGVTLSKVWGQDLSRETRQLERKLDALQEGLLEARMVPVGQVFDRLARLVRRIAREVG
                     KEIDFVIGGGDVELDKLIVEELSDPLMHIIRNAIDHGAESPEARLAAGKSRRARVSLQA
                     EQKGNHVLIKVSDDGAGIDELGVRELALRKGLITEAQAREMSRRELLNLIFLPGFSTAR
                     SVSELSGRGVGLDVVKNNIGNLSGIIDVWSERGMGTAFHITLPVTLAIIRALVVGVSGR
                     TYAVPLNSVLEILSVKPAEIRTVERREVLDLRGTTLPLMRLARVFNHPERPADRYFVVV
                     AGLAQERLGIAVDELQGQQDIVVKSLGGRLQGVRGISGAADLANRRTVLVLDVGALLEE
                     GMSSERRRA"
     gene            17156..17722
                     /locus_tag="CYFUS_RS17645"
                     /old_locus_tag="CYFUS_003489"
     CDS             17156..17722
                     /GO_process="GO:0006935 - chemotaxis [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1201: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002616928.1"
                     /locus_tag="CYFUS_RS17645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003489"
                     /product="chemotaxis protein CheW"
                     /protein_id="WP_095986287.1"
                     /transl_table=11
                     /translation="MPALSVLLDSFFYRPDEDVGLIQEVVAGTDESLEPVAEEVPEEYL
                     AFQLEGELYAVPIHGVREIVKVPSLTEVPRAAPNLLGVMYLRGEVLPVYDIKVKLRLAD
                     KAPLVAGPDATVTPPRGTRIIVVQASDGLAGIWVDAVNEVVRLRPSMLELAPPGVGGGE
                     RDCVVGLGRRKQELFILLDLWQALS"
     gene            17719..18288
                     /locus_tag="CYFUS_RS17650"
                     /old_locus_tag="CYFUS_003490"
     CDS             17719..18288
                     /GO_process="GO:0006935 - chemotaxis [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1201: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015350751.1"
                     /locus_tag="CYFUS_RS17650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003490"
                     /product="chemotaxis protein CheW"
                     /protein_id="WP_095986288.1"
                     /transl_table=11
                     /translation="MRQRINVLTRVTQSRAEEEAAAERDPLVQLCAFFVGTEEYAVDIM
                     RVEEILQPQRLTPLRGSPPFIEGVIRLRGAILPVVDLRKRLLGQPSPVDTPKTRLLVCW
                     LGRRRVAFTVDRVSEVVRLRRSDIKPALGAVGSAPFVVGVYGAPEGRDASAPGGERLKL
                     LLDVKALLLAEMLAESNSNPNRRVNG"
     gene            18285..20264
                     /locus_tag="CYFUS_RS17655"
                     /old_locus_tag="CYFUS_003491"
     CDS             18285..20264
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630203.1"
                     /locus_tag="CYFUS_RS17655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003491"
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="WP_095986289.1"
                     /transl_table=11
                     /translation="MSEEGRNAEEVRYRALLDLDVSRPEAREELVTGLHDESWRVRRAA
                     AEGLVRLPERGAVVERLIAVLGERDETGARNAAAESLAGMGASAVQPLVHLLGHADPDL
                     RKFAADILGQLALPEAEGALVAVLLEDGDLNVRVAAAEALGRVGGRGAAFALERVLSNP
                     EPLLRLSALESLAALRHPPPLADVVPLLNNPLLKRSAYRVLGLIERTEVVALVCRGLAA
                     SESRSTREAALVALGQHSARMADGARPAMYAAVGEALRRLLGAVSWVTSALESGDIEVK
                     TGALVAAAALREPRLAPLVAEVAQEERLVPEVMRTLACFGPETGRELLASMDRLSFPAR
                     EAAGQVLVDMVDESFVPELVQMLDWGEVDLKGVAARALGRTGALEAVEPLAGFLSNPEL
                     AGVAARALVALSAGFRAQVLQVLQTSLEQGAQPVVLNALVRVGGTAQLPLVRRIAREAS
                     VPLRATAVEVLAAVDPSGGLELARVALVDEAPRVRAAAVRVLGQVGDVSLAPLLQRALS
                     DDALEVRLAALEAVGECGAVALAEDLEALVRHPDGAIAFRAVRSLARLGVLRDEVIQHA
                     VAHEDHEVVKAALLAGAASGGGEALALGLLGHAHWDVRAAAARVLADSREERLLPPLMN
                     ALLSETDALARRALVDAVERLSGR"
ORIGIN
        1 tgccgggcgg tgaccgaggc aagcgccacc cggggcgtgc tcgtatgtgg cacgggcatg
       61 ggcatggcca tcatggccaa caagctcccg ggcatccgcg cggcgttgtg cacggacgag
      121 ttcgtggccc gcatggcgcg cgcccacaac gacgccaacg tgttgtgcct ggggcagcgc
      181 gtggtgggcg ccggactcgc ccgcagcatc ctggaggcct tcctggccac ccccttcgaa
      241 ggcgggcggc accagcggcg tctggacaag attcgagagg ccgagtcccg gtgacggccg
      301 gccttccaac cgaggagaca caatccatgg agaacacccg tctgctggcc gaggtcgatc
      361 ccgaaatcgc ccgtgccatc caggacgaga cgcggcgcca ggaagaaggc ctggagctga
      421 tcgcctcgga gaacttcgtc agccccgcgg tgatggaagc cgcgggctcg gtgctcacga
      481 acaagtacgc ggaaggctac cccggcaagc gctactacgg cggctgcgag gtggtggacg
      541 tggccgagac gctcgccatc tcccgcgccc gtgagctctt cggcgccgag tacgccaacg
      601 tccaggccca ctcgggcagc caggcgaaca tgggcgccta catggcgctg atgaagccgg
      661 gtgacaccct gctcgcgttg gacttgaact cgggcggtca cctcacccac ggctccgcgt
      721 tcaacttctc cggcaagctg tacaaggccg tgcactacgg cctcacccgg gacaccgaga
      781 cgatcgacta cgcgcaggcg gccgccctgg ccaaggagca caagccgcgc gtggtggtgg
      841 tgggcgcctc ggcctatccg cgcatcatcg acttcgcgaa gttccgcgag atcgccgaca
      901 gcgtgggcgc ggcgctcatg gtggacatgg cgcacatcgc gggcctggtg gccgcggggc
      961 tgcatccctc gccggtgccc ctggcggaca tcgtcaccag caccacccac aagacgctgc
     1021 gcggcccgcg cggcggcctc gtgctgagca aggagcccta cgccaagacg ctcaacagcc
     1081 agatcttccc gggcatccag ggcggcccgc tcatgcacgt catcgccgcc aaggccgtgg
     1141 ccttccgcga ggcgctcagc cccgagttca aggcctacca gaagcagatc gtcgccaacg
     1201 cccaggcgct cgccgaggcg ctgcagaagg gcggcctgcg gctgtgctcg ggcggcacgg
     1261 acaaccacct gatgctcgtg gacctgcgtc ccaagaagct cgtgggcaag gtggccgagg
     1321 aggtgctcgg caaggcgggc atcacggtga acaagaacat gattccgttc gatcccgaga
     1381 agcccacggt gacgtcgggc gtgcgcatcg gcactccggc cctcaccacg cgcggcatga
     1441 aggaggcgga gatggccacc gtgggcgcgc tggtggtcga ggcgctggac aacgcctcgg
     1501 acgagcagcg gctggcgagc atccggggcc gcatccagga gttcacccgg agcttcccgc
     1561 tctacgcctc gcgcctgaag tagcgcgtgc catgcgttgc cccttctgcc aggaccccga
     1621 gaacaaggtc atcgactcgc gcgagtcgca tgagggctcc gtcatccgcc ggcgccgcga
     1681 gtgtctgcaa tgcaagcggc gcttcaccac gtacgagcgc gtggaggaaa tctacccgct
     1741 catcgtgaag aaggacggcc ggcgcgagac gttcgatcgg gacaagctgc tcgcggggtt
     1801 gcagaaggcg tgcgagaagc ggccggtgtc ggcggaccag ctcgaggaga cgctggtcgc
     1861 cgtggagcgg ctgctgcaag gggtggggga gaaggaagtg ccctcgtcgg tcatcggcga
     1921 ggaggtgatg cgtcggctgc acgcactgga cgaggtggcc tatgtgcgct tcgcctcggt
     1981 gtaccggagc ttccgtgaca tcaccgagtt catggcggag ctcaaggact tgctgtcgga
     2041 ccggacgcgc gagcacaagc cgccgcgtcc accggacaag gacgggtaac gggcgatgcg
     2101 gctcttgacg cgagcacggt tgcaggcggg gcgcgccccc cgggccaagc gcacggcgga
     2161 tttcgatcgg gcggtggccg agttcttcat gcgcctggcg ctggaggagg ccgccaaggg
     2221 gctcggccgc accagcccca acccggtggt gggcgcggtg ctggtgaagg gcggccgcat
     2281 catcgcgcgc ggctatcacc gccgggccgg cacggcgcac gccgaggtgg tggcgctgga
     2341 ggccgcgggt ggcaaggctc gcggcgcgga tctctacacg acactggagc cgtgtgatca
     2401 ctacgggcgc acgccgccgt gcagccaggc gttgatcgac gcgggcgtgc gccgggtcat
     2461 caccgcctcg tcggatccca accccaaggt gaatggcaag ggcgtcgccc ggctgcggcg
     2521 tgctggcgtg gaggtgctca ccggggtgct caaggacgag gcggatcagc tcaaccgccc
     2581 cttcttcaag gcgatgcgca ccggcctgcc cttcgtcacg ctcaaggcgg cggtgacgct
     2641 ggacggcaag ctggccacgg ccacgggtga ctcgcgctgg gtgacgggag aggaggcccg
     2701 cgcctgggtg caccggctgc gcgatcgggt ggacgtcatc ctcgtggggg ccaccaccgc
     2761 ccgccgggac aacccccagc tcaccacgcg cctgcccgag agcgcgggga aggatccggt
     2821 gcgcgtggtg gtggactcgc acttgcgtct gccctcgacg ctccaggtct tcacccagcg
     2881 ctcccccgcg cgcaccgtgg tggccacgct ggaggatccc tcggctcgca aggccaaacg
     2941 cttcctggcg acgggcaccg acgtctggca gctcccggag aagcagggcc gcgtggatct
     3001 cgaggccctc atgcgccgtc tcgcccggga gggcctgaac cacgtcctgg tggagggagg
     3061 cgcggagatg tacggctcgt tcctgcgcga ggaactggcg gatgagctgc tgctcttcgt
     3121 cgcccccaag ctgatcggcg gcgagggcct gtcctggtcg ggatcgctgg gcgtcaagca
     3181 gatggcgcgg gcgctcaccg tgggcgcgct gtccatggag caggtcggca ccgacctgct
     3241 gttgcgcgcc cggctcgacc ccgcgcggtg agcgcgcggg gggcgtgtgc tcaggccgtg
     3301 cccgagagct ggatccgggg cacctgggcc tggggcaggc gtggccgcag gttcagccac
     3361 atgccgtcct tggtgcgcag gttggtgctg acgcgctcct ggggcaggcg tcccgggacg
     3421 gaggacagct cgtagcgcga gacgatgcgg gccatgatga gcatgccctc gagcagcgag
     3481 aactccttgg cgatgcactg gcgctggccc gagccgaacg gcagccacgc gagcttgtgc
     3541 cggccctccg agcgctccgg cgtgaagcga tccggatcga acgtcagcgg atcgtcccag
     3601 atgcccgggt ggcggtggat gaggcgcgtg aagatcacca tcatgacgcc cggaggaatc
     3661 cggtacccgt cgatctcatc ctccaccacc gacaggcgcg gcagccacac cgagggcgag
     3721 tggatgcgca gtgcctcctg caacacgttg cgggtgtagg gcatccgcat cagatccgcg
     3781 aagccaggcc tgcgtgtgcc cacgacggca tccagctcca cccgcacctt gtcggtgacc
     3841 tccgggtgct gggtgagcgc gtgcaacacc caggtcatgc ccgccgcggt cgtgtcgtag
     3901 cccgcgatga agaagccgag ggcctcgtcg cgcagctgct cgttggtcat ccgctcgccg
     3961 gactctccat ccaccgcctg tagcaacagc gagagcaggt tgtcctcgcc cgaggcctgt
     4021 tcgcgtcccc gctcgatgag ccgccgcatg atctcgtcga tcatcttgat cgactcgcgg
     4081 tagcgttgcc ggccagggac cggcatccat tccggcaggg agtgcgtcac catccccgcg
     4141 atgaagtact cgaggatgaa ggagaacgcc tgggcgacct tctccgcgtc atccttgtcc
     4201 agcccggagc cgaacagggt gcgcaccagc acggtcatcg tcacccggga cagggcgacc
     4261 gagacgtcga agggcttgcc ctccagggcc gccagatccc actccagcag acactcgtcg
     4321 atggcctcca ccatcgtgtc cgtcatcagg ctcacgcgct gatgatggaa cgagggctgg
     4381 atcatgcgcc gctgccgctt ccagaaggcc ccctcgctca tgggcagcgc gttgcccatg
     4441 aacgtccgca tcgagtccca catgggtccg cccttggagt acttgtgagc gtgctccacg
     4501 aggacgtgat ggacgtagcg gggatggcac aggccaatca cctgggtgaa gcccaggtcc
     4561 atgctgaaga tgtcgccatg ctcgcgctgg gcctgctcca tgaaggacag cgggttggca
     4621 atcaagcgag gcaggcatcc caccaggggg agggaggaaa cccttggggg cagtgatcga
     4681 tctgatgacg tttgggatgt ggtctcgctc atgcgtgtcc ccctgcgacg cctttccgaa
     4741 tcaagggtgg cggagagtgt ccggagggcc ccttgagccg ctcccggagt tcaggtcctc
     4801 gcaccttaac atggtcaaca gtccccacga gccagggggg gtctcaatat ccgagaagac
     4861 acatgcctcg cttccatgcc cgatcgcgtc ctgtccccac gcctcttcgg gcaagccgcc
     4921 tccgtcgggt ctgaaagcaa tctcacggaa gaatttcaat atggcggtgc tccgggcgcg
     4981 ccagggtcgc acgtcgcgcg aagcgtggag gagggcctgg ccgtcctggg gagacgcgct
     5041 gttcgtgccg cgtgcgtggg gtgacctgcc ctcgcgggcg aagcggatgg cccggggatg
     5101 tcctggggtg gatgacgcgg agcagccctc ggagttgttc tcgacagccg agaggccgac
     5161 tactagtgtc ggtcgcgtgc caagtccgac caactcagac tcgtcgctgc aggggctctc
     5221 gctcaatccc atcagccccg agaacctcgt caatccgatt ccgctctaca aagcgttacg
     5281 tgagagcgag ccggtgtact ggtcggacac ggtgcacgcc tggctcgtca cgcgctatgc
     5341 cgacgtggtg gcgtgctttc gcgatccgcg gttgagcgcc aatcgcacca acttctacga
     5401 gcaacagctc caggggatgg gtggggacgt ggccggcgag ttcctcaagt cggcccggtt
     5461 gcagatgacc atgcgcgatg gcgcggacca catccgcgtg cgtcggcagg ccagtccggg
     5521 cttcaccccg caggggctcg acacctaccg tcccgccatc cgccagttca tgggcatgct
     5581 gctggatcgc gtgcaggagt gggggcacat ggacgtggtg aaggagattt cgtaccagct
     5641 cccgccgctc gtcatcgccg agttcctcaa catccccgcg caagaccggg agcgcttcca
     5701 ggcctgggcc cgacccctgg cggacttcgc caatccgaag ccgggcgtga acatgcagga
     5761 cgtggcccgt gaggcgagcc gggtcaccgt ggagatgaac gcctacctgg cggagcggat
     5821 cgaggagcgc cgtcaccatc caggcagcga catgctcagc ctgatgatcc acgcccagga
     5881 actgggccgg atgacggagg atgatctcgc ggccaacacg ctgctcatcc tcaccgcggg
     5941 acacctgacc accacggatc agatcagcaa cggcgtctac gatctgctct cccatcccga
     6001 gcagcgccag aagctgcaga atgaccgtac cctgttgcgc tccgccgtgg aggagatgct
     6061 gcgcttctcc cccgcggtcc ccttcgcctt ccgcgtcgcc gcgcaggact tcacgttgca
     6121 tggcaaggac atccgcaagg gcgacaccgt gttcctcggg ctggccgcgg ccaaccggga
     6181 cccctcggtc ttcacggatc ccgaaacgtt cgacattacc cgggacagcg tccagcagaa
     6241 gcacctgacc ttcgcgttcg gcgcgcacca ctgcctgggc gcgggtctgg cccgccgcga
     6301 gatggagatc tccatcgaga tgctcctgga tcgactgccc caggtgcgtc tggacgagac
     6361 gaagaagccc cagcacaagg tcggcctcgt cttccgcagc ttcaactcgc ttcatctgga
     6421 ctggtgacgg ccgccgcgcg ggtggctcgg accggcgggg gggttccatg ccgggtcagc
     6481 gaccaaggag gctggatttt cgggcggaga gggacggatc gggctggcga cttgctcccg
     6541 gacccccgtc cgattgatga tgggggagcg taccggtgca tgaacctccc cacggccaca
     6601 cgaatggtgc ctgagcccac accctgacct gggaattcct gccgcaggtg cagacctgga
     6661 agaacgccat gcccgccgac aaacagatca ctcagaccat caacaagatc ttcctcatcc
     6721 gacagttctt cggatcgatc atcttgtccc ccgcgacgac ctacctcatc aacaacctct
     6781 cggggctgac ggacgatgag atgtcgaaga cgaccaagtt cacgatgccc atcgtgttcg
     6841 gcctcttcag tctgatcgtc ccctacctgg tgatgaacta tacgatccgg cgggcgttct
     6901 ccaccctgcg gggggatcac gaagggtcca agatcgagcg gttgttgaag attcccggcc
     6961 agctcgaggc gctgatgatc ctgtgcgcca tcctggggtc cacgttctac atcaccgttc
     7021 ccatcctctt tcacaagaag agcctggcac ccatcccgtg ggtgttgagc acgacgctgc
     7081 tcgtgttgat gctcaacttc atcaacgagc ggttgatcta cgagcgcatc ctgcgcccct
     7141 tcgccatcga ggagttccac aagcacccca aggcggtcat ccggggaacg ggcttcttct
     7201 ggccgcgcat gaagtggtac ctgccctacg ccttcggcgt cttcgtcgcc tccacgctga
     7261 tgctcagcac gacgatcatc gccaagcagg tcatcatcac cttcgacgaa ctcaaccagg
     7321 tgatgcagac ggatgccgcg cacatcggcg agcacatcag ccgggtcgtc gatctggtcg
     7381 tccagcgcgc cgcgatcccg ctctcgctca tgggtggcta cctgctcgcc atctcgtcca
     7441 tcgccgcgtg gttgctggcg cgccggcagg agctgggcgc cctgagcgtg caggaggcca
     7501 tcgagggtct ggcgtctggc tcgcccaagc tgccggattg gatctccacc gacgagatcg
     7561 gcgatctggc gggctccacc tcgcgcgcct tcgagaagct cagcgccttc tcgctgtcgc
     7621 tgggtgagtc ggccaactcg ctgcgtggtt cggccgagcg cctgggctcg tccgcgagcg
     7681 agcagagcac ggtgctcacg cggcaggccg ccgcgcttca ggagacgcag gtcaccgcgc
     7741 aggagatcaa gcagacctcc gagctcgcct cgcagaaggc ggagaacgtg ctgcagcaga
     7801 ccacccgcgc caatcagatc agcaccgagg cggtggcggc cgtgcgcacc agcctcgagg
     7861 agatccagga agtcggccag caggtggcca agatggccag ctccatccag tccctggaga
     7921 agaagacgca gcagatcgcc agcatcaccc gcacggtgaa ggacctggcg gaccagtcca
     7981 acatgctcgc gctcaacgcc gccatcgagg cggtgcgctc gggcgagcac ggcaagggct
     8041 ttggcgtcgt ggcgcgtgaa atccgcgcgc tggccgacca gtccatccgc gccaccaaca
     8101 acgtgaacag catcctgttg gacatcggca acgccatgcg ctcgacggcg gccatgacga
     8161 ccaagggcta cgagaaggtc gagctgagcc tcaagggcat caagggcttc gagggcagca
     8221 tccagcagct gtcctccatc gtgcgggaca acgcggactc catccggcag atcaccgcgg
     8281 ccgtgacgca gcagaacgtg ggcatcagcc agatcttcca ggccgtcaat gatctcaaca
     8341 acatgatgga acagacgatg ggccagatgc agacctcgga agaggcctcc accgtcgtgc
     8401 agagcgtggc ggaccaggtg tcgggtctcg tcacctcgta cggctggaag gaagccgccg
     8461 agcgcgctcg tcagaaccgc accacctgag ccgcgcgtcc ggtcttctcg tactcctcca
     8521 tcttcggatc agggacatgt caaagggcac attctcgtcg gcctccaggc ggtttggagg
     8581 ccggcatgcg gtggtcatcg gcgggagcat ggcgggcatg gccgccagcc gcgccctggc
     8641 gtcacacttc gagcgggtca ccctgatcga acgggatcgg ctcccggaga agcccgagct
     8701 gcgcaaggga ttgccccagg agcagcaggc ccacggcatc ctggccaagg ccgtggagat
     8761 cctcgagggg tacttccccg ggctgtggca gcagatggtg gccgcgggct ccaacgtcct
     8821 ggacatgtcc gacgtggcgc tgtaccgggg cggcatctgg caggcccgcg ccacgccggg
     8881 gctgacgctc tacatccaga cccggaccct gctggactcg gtgatccgct cccgcgtccg
     8941 ggagatctcc aacctccaga tcctggacga gtgcgaggtc gtcaagcccg tggtgacgag
     9001 caaccgcgtc gccgtctggg gcgtggaggt gcgtcgccgc aagcaggagg ccacggagat
     9061 cctcgaggcg gatctcgtcg tggacgcgac gggccgcggc tcgcgcatgc cccgctggct
     9121 cgaggagctg ggactgcccc gcgtggagga gacccacgtg cggatcgacg tgggctacgc
     9181 cagccgcaag gtgcgcaagc tccagggggt caccaccaac tggaagacgc tctccatctt
     9241 cccgacggct ccgcgggaga cgcgcctggg cgcgctcgcc ccggtggagg gggacacctg
     9301 gctggtgacc ctggctggcg ccctgggaga ccacgctccg ggtgacgagg cgggcttcct
     9361 ggagttcgcc cgggccctgc cgcagccgca cgtctacgag atgctccggc gctgcgagcc
     9421 cgtgtctccg gtggccgctc acaagtttcc ctccagcatg cgccggcact acgagcgcat
     9481 gacgggcatt cccgaggggc tcgtggtgct gggagacgcc gtgtgcagcc tcaaccccat
     9541 ctatgggcag ggcatgacgc tgtccgtgct ggccgcctcc ctgctggagg agtgcctgtc
     9601 ggagcaggcc ccgagggcga tgatggggtt cggacgacgc ttccaggcga agctctcgcg
     9661 catgcacgac atgccgtgga cgatgggcgc gggcgaggat ctggtctacc cctcggtgga
     9721 aggaccccgc cccctgtggt ggaaggcgat gcagggagct tccgggcatc tgcagtcgct
     9781 cgcggcgtat gatccggtcg tcaccaccgc gttcgccaag gtgatgcaca tgacgggctc
     9841 gccgctggaa ctggcccacc cctccatgct gctgcgcatg gtgcggggtc cccagggcga
     9901 gggaccggga gagtccccgg tgatgcagtt cccggagggt tccgcgcctc cgtccaagac
     9961 cgtggccagt gtcgcctgat ccccccggaa acacccttcc atgagaacga ttgcccttcc
    10021 cccgctccgt ctgccgtttc cccagaagct caatccacac aaccatcagg cctggccgca
    10081 cacggtggag tgggtgaagc gcttcaacct gctgccggaa aaggcgatcc cctacttccg
    10141 cgcgcaggac taccactggc tgtccgcgta tgccttcccg gaggcggacc tcgagcagtt
    10201 gatcctcatc aacgactgca tgacggcgtt ctacctcttc gacaagcact gggacgacgc
    10261 tccgcccgac gcgctcgagt cgatgcaggc tccgctgctc gatgccctgt ggggtcggcc
    10321 gccaggggat gctccggagg ggccgctcga gaacgcgatg cgcgacatgc ggcggcggat
    10381 gatgaagtac agcaccgacg cgtggatgac gcgcttctgc gagagcctcg aggcctactt
    10441 caaggcgtgt gtctgggagg ccaagaacaa gagcaacagc caggtgcccg acgtggcctc
    10501 ctacatccgc atgcgcgagg cgacgggcgc ggtgcagccc agcttcgagc tggcgggggt
    10561 gctcgggctc gtccagattc ctccgagcgt gctggaggag ccgatcatca agcggctcaa
    10621 ccagctggcc aaccacgaaa tcaccctgtt caacgacatc atctccctgg agaaggagat
    10681 gcgcgtcggg gacatgcaca acctcgtttt catcatccag aagcagaacg agaagaacgg
    10741 gacggagtgc tcgctcgagg gcgccatgaa gcaggcggcc aagatgcacg acgacgaggt
    10801 gctcgagttc ctcgagctgg aggccaaggt gccctcgtgg ggcgagcccc tggacaccga
    10861 ggtgcggcgc tacatcgacg tgctgcggtg ctggatgcgc gccaacatgg actggtcgct
    10921 gatgtccacg cggtacaaga cccccgaggc ccccgcggcc tgagccgtcc gcctgcctgg
    10981 tgccccaggt ggggcgtccg ggctttcgtg gcccgtcccg agggaaggtg cggaacccgg
    11041 gacgaggatc cgttataagc ccgtcgcaat gttcaccgga ctcatccagg acatcggcgt
    11101 ggtggagcga gtcatccccg gcgggatgac ggacttgtgg attcgcacgg cgctgggcgc
    11161 gcgggacttc gcgctcgggg aatcgatcgc ggtggatggc gcctgcctca ccgtggtgga
    11221 gcgcgcggga gactccttcc gcgtccaggc cgccccggag acgctgcggc gcaccaccct
    11281 gggcgcccgg cagccgggct cgcgcgtcaa cctcgagcgg gcgctcgccc tgggagaccg
    11341 gctgggcggc cacctcgtcg ccggccacgt ggacgcggtg agcgaggtgc tggagacgcg
    11401 cgccgagggc ggctcgtggg tgatggtctt ccgcctcccc gccgaactcg cccccttctt
    11461 catcgagaag ggctcggtgg ccatcgacgg catcagcctc accgtcaaca cggtggggac
    11521 ggatcgcttc agcgtccagc tcatccccga gacgcaggag cgcaccacgc tgcgctcgcg
    11581 cggagtgggc gagcgggtga atctggaagg cgacatgatt ggcaagtacg tggcgcggct
    11641 cgtgtcgctg cgccagggcc cgggcggcgg tggcctctcc gaggcggtcc tcaaggcggc
    11701 gggcttcggc ggttgagcac agggaagcat tcaggagcac gcatggcgcg cggcaggcag
    11761 cacgagtcgg acagcatcac cctggtggag aaggcgctcg cggagatccg caagggccgc
    11821 atggtcatcc tcacggatga cgaggaccgg gagaacgagg gcgatctcgt catggcggcg
    11881 gagaaggtga cgccccagga catcaacttc atggccaccc acgggcgcgg gctcatctgc
    11941 ctggcgctcg acgaggagcg catccggcgg ctcaacctgc ccctcatggt gcaggacaac
    12001 acctcgtcct tccagacggc cttcaccgtc tccatcgagg cggcccaggg ggtctccacg
    12061 ggcatctccg ccgcggaccg cgcccacacc atccaggtgg ccgtggcgcc gaacgccagg
    12121 ccgtcggacc tcgcgcggcc cgggcacatc ttccccctgc gcgcccggca gggtggggtg
    12181 ctcgtgcgca ccggtcagac cgagggcagc gtggacctgg cgcgcatggc gggactgcgc
    12241 ccctcgggcg tcatctgcga gatcatgaac ccggacggca ccatgtcgcg ccggccggat
    12301 ctggtgaagt tcgcccgcaa gcaccagatg gtgctcctgt ccgtggccga catcatccgc
    12361 taccgcctgg agcgcgagcg gctggtgcgg cggctcgagg agacgacgct ggagcgccgc
    12421 ggccagggca gcttccgggc ctacacctac ggcagcgacg tggacagcgc ggtgcacgtg
    12481 gccgtggtca agggcgagct gtccggtcgt gagccggtgc tcacccgcgt ccaccgcacc
    12541 tgtctggtgg gggatctgct gggcagcgcc gggtgcgagt gtggcgtgca gctcgagcgg
    12601 gccttccagg ccatccacga ggccgggcgg ggggtcatcg tcttcctgca gggggactcg
    12661 gcgcggaaga accggctgcg ctgcacccat gtctccaacg aggagctggt gcccgggcac
    12721 aaggatcaga cgcgcctgcg cgagttcggc gtgggggcgc agatcctcaa ggacctgggg
    12781 ctcacccggc tgcgcctgct caccaacaat cccaagaaga tcgtggggtt ggagagctac
    12841 tcactggagg tggtggagca ggttccgctc atcccggccg ccccggcgac ccggcgcgtg
    12901 gccgctcgcc gtcccccgcg cggccgtcag gcctcctgag cgccgggggg tgggggaaaa
    12961 ctctgtcggg acgccagccg ggtggctggt gtagagaggt cgggacatgc ctcgctacat
    13021 cgaaggtgac ttcctccccc ccaagggccg cttcgccatc tgcgtggccc gtttcaacgc
    13081 gttcatcacc gaggagctgg tgaagggcgc gctggacacg ctggtccgcc acggcgtcgc
    13141 cgacggggat atcgacgtat tccgttgtcc gggcacctat gagctgcccg cgctcacgcg
    13201 gcgcgtgtcg gagacgcgct cgtacgtggg catcatcacc ctgggcgccg tcattcgcgg
    13261 cggcacgccc cacttcgact acgtgtcggg cgagtgcacc aagggcatcg gccaggtggc
    13321 cttcacctcg caggcggccg tcaccttcgg cgtgctcacg tgcgacacgg tggagcaggc
    13381 gatcgaccgg gcgggcgtga aggccggcaa caagggctcg gaagcggccg cggcgtgcat
    13441 cgagatggtc aacctccacg cgaagctcgc cacgctgacg gacgggaaga ggagctgaca
    13501 catgggtgcg cgcagaacgg cacgcgagcg ggccctccag gcgctctacc agatggagat
    13561 gacgccgggc tccatccatg atgccctgga agcggcctgg gccgccgccg aggtgacgaa
    13621 caaggagccc gaggcggtga agttcgcccg cgagctcacc gagggcgtca tggcgcaccg
    13681 cgcggagatt gatcggctca tcgagcagca cagccacaac tggcgcctgg atcgcatgtc
    13741 acgcatcgat cgcaacgtgc tgcgcctggg cgtcttcgag ctgaagtacc gcccggacat
    13801 ccccaagaag gtgtcgctca acgaggcggt ggagctcggc aagaacttcg gcaccgagga
    13861 gtccagcgcc ttcgtcaacg gcctgctgga tcgcgtggcc gtcgccctgg ggaagcagtg
    13921 aacgtctccg cgcacgagct gggcctgggc ggattggacg cgctggcgga cgtggacgcc
    13981 ctgtgcctct tcgtgggcga ggacgaccgg cccctgcccg gcaccgccgg ctatgtggac
    14041 tggcgcttgt gcggcaccct gtcgcgcgtg ctccagtccg gcttcttcgt gggcgcccag
    14101 gacgactcgc tcctgctgcc caccgatggt cgcttcagca tcccccgcgt cttcgtcatg
    14161 ggcctgggcc ggcggcgcgg cctggagccg tcctccctcg gcgaggcgct cgcctccgcg
    14221 ggcaaggtgc tcacccgggc cagggtggag tccgttgccc tggaagtccc cggacaggac
    14281 gccctggacg aatccgtccg cctctccgcc ctccaggaac acttcctccc ggctttccgg
    14341 ggaaggaagg tggccgtgct ggcggacaag gaactcgctc gccgcctttc cggccgcaag
    14401 ggctgaatct cgccccctct cgtccttctg gtaggatgtg aggctcggtc gcacgaaatg
    14461 acgtccaaga ttctcatcgt ggaggattcg aaggcctcgc gggagttgat ctccgcgacg
    14521 gtggagtcca tccccgggct ggaggccatc gccaccagca gcggtctgga ggcgctcaag
    14581 ctgctgcccc agcacgcctt cgcgctcatc atcaccgaca tcaacatgcc cgacatcaat
    14641 gggctggagc tcatccgctt cgtcaagacg aaccccacct tgcgcgacac gcccctgttc
    14701 atcgtcacca ccgagggccg cgagaaggac cgtgaccggg gactggcgct gggcgcggcg
    14761 gagtacctcg tcaaaccctt ctccccgcag agcctggaag ggctcgtgcg gcgctacctc
    14821 aagctcgcgt gaactccgcc ggcaaggccc tggcggagtt cgtcgccgag ggaacggaaa
    14881 tcctcgagtc gctgggcaag gaactgctcg tgctggatca acagcgcggg gtggaacccg
    14941 agccggacat catcaacggc atcttccggg cggcgcactc gctcaagggc ctggcggcgc
    15001 tcttcggcca ggagcgcatc gccaggctcg cccaccagtc cgaggatctg ctggatcggc
    15061 tgcggctggg ccggctgtcg ctggatgacc aggtgctcga tctgctcatc gagtcgctgg
    15121 acgtgctcca ggccctgctg gcggaggccg cgcgcgagga gtcctcggac gccttgaacg
    15181 agcgcgtgaa ggagctgggc gagcgcctag ccaacctggg caccgcctcg gcggcggccg
    15241 acgaggatcc gctcgatcgg ctggagctgg acccgcaggt gcgctccgtc ttcaccgagt
    15301 acgaggagca ccgcctgcgc gagaacgtgc gccggggcgt ggcgctcttc cgcatccggg
    15361 ccgcgttcga cctgtccgac ttcgacaccg ggctcaccga gctcaacgtg cgcctcaagc
    15421 ccctgggcga ggtcgtcagc acgctgccct cgtcggagcc cggaggcctg tcgggcatcg
    15481 cgttcgatct catcttcggc tcccgggtgt ccgaagcgga gctggcggcg aagctgcaag
    15541 gtacgcccgc gcagctcttc gcgctcaccg tccgtccgag tgccgcggcc ctggtcccgg
    15601 tcgggtccgc cccggagaca ccggccgcgc cgcttcccct cgcgctccca cccgccgagg
    15661 cgcccgcggc gaagaagacg acccggcgca agcctcgcgc ttccaagacg ggcgcggggt
    15721 cgtccacgtc ggcggaggac gtggcgcccg cggacgctcc gctggtgaag gcctcctccc
    15781 tgcgcgccgt cgagccggtc gttccggcgc tccccgcgtc cgacacctcc tcgctgcccg
    15841 tggtgcgcac gctgaccgag gagccggtgg cgccgcgtgg ccccaaggcg gagagcgagt
    15901 cggcgcgcag cctgacgcag acggtgcgcg tggacatcag ccgcctggac gcgttgatga
    15961 acaccgtggg tgagctgctg ctcatcaagg cgaacctgca gcgcatggcg gagagcgccc
    16021 gggtggacgc cggggtgacg ctctccaagg tgtggggcca ggatctctcg cgcgagacgc
    16081 ggcagctcga gcgcaagctg gacgcgctcc aggagggcct gctcgaggcg cgcatggtgc
    16141 cggtgggtca ggtgttcgac cgactggccc ggctggtgcg ccgcatcgcg cgcgaggtgg
    16201 gcaaggagat cgacttcgtc atcggcggcg gcgacgtgga gctggacaag ctcatcgtcg
    16261 aggagctgag cgatccgctc atgcacatca tccgcaacgc catcgaccac ggcgccgagt
    16321 cgcccgaggc ccgactggcg gcgggcaagt cacggcgggc ccgggtgtcc ctgcaggccg
    16381 agcagaaggg caaccacgtc ctcatcaagg tgagcgacga cggggcgggc atcgacgagc
    16441 tgggggtgcg tgagctcgcg ctgcgcaagg gcctcatcac cgaggcgcag gcgcgcgaga
    16501 tgagccggcg cgagctgctc aacctcatct tcctgccggg cttctccacg gcgcgcagcg
    16561 tgtccgagct gtcgggccgg ggcgtgggcc tggacgtggt gaagaacaac atcggcaacc
    16621 tgtccggcat catcgacgtg tggagcgagc gcgggatggg caccgccttc cacatcacgc
    16681 tgcccgtcac gctcgccatc atccgcgcgc tcgtcgtggg ggtgagcggg cgcacctacg
    16741 ccgtgcccct caacagcgtg ctggagatcc tctccgtcaa gccggcggag atccgcacgg
    16801 tggagcggcg cgaggtgttg gatctgcggg gcaccacgct gccgctcatg cgcctggccc
    16861 gggtgttcaa ccaccccgag cgtcccgcgg accgctactt cgtggtggtg gcggggctgg
    16921 cccaggagcg cctgggcatc gccgtggatg agctgcaggg ccagcaggac atcgtcgtca
    16981 agtcgctggg tggccgcctg cagggcgtgc gggggatttc gggggccgcc gacctcgcca
    17041 accggcgcac cgtgctggtg ttggatgtgg gtgccctgct cgaagagggg atgagctccg
    17101 agcgccgccg ggcctgaatc gctcccgggg ccatgggcct gctattcttg gcgccgtgcc
    17161 cgccttgtcc gtcctgctcg acagcttctt ctaccgcccc gatgaggacg tgggcctcat
    17221 ccaggaagtg gtggccggga ccgatgagtc gctcgagccc gtcgcggaag aggtgcccga
    17281 ggagtatctg gccttccaac tggagggcga gctctacgcg gtccccatcc acggcgtgcg
    17341 ggagatcgtc aaggtaccat ccttgaccga ggtgcctcgc gccgccccca acctgctggg
    17401 cgtcatgtac ctgcgcggcg aggtgctgcc cgtctacgac atcaaggtga agctgcgcct
    17461 ggccgacaag gcgcccctgg tggcgggtcc ggacgccacc gtgacgcctc cgcgcggcac
    17521 gcgcatcatc gtcgtgcagg cctccgacgg gctcgccggc atctgggtgg acgccgtcaa
    17581 cgaggtggtg cggctgcgtc cctcgatgct ggagctggcc ccgcccggtg tgggcggtgg
    17641 agagcgcgac tgcgtggtgg ggctcgggcg gcgcaaacag gaactcttca ttctgctcga
    17701 tctctggcag gccctttcat gagacagcga atcaacgtcc tcacccgcgt gacgcaatcg
    17761 cgcgccgagg aagaagccgc ggcggagcgg gatccgctcg tgcagctgtg cgccttcttc
    17821 gtgggcaccg aggaatacgc cgtggacatc atgcgggtgg aggagatcct ccagccccag
    17881 cgcctcacgc ccctgcgcgg ctcgcctccc ttcatcgagg gcgtcatccg gctgcgcggc
    17941 gccatcctcc cggtggtgga cctgcgcaag cggctgctcg gccagccctc acccgtggac
    18001 acccccaaga cgcggctgct ggtgtgctgg ctgggccgcc ggcgcgtggc cttcaccgtg
    18061 gaccgggtgt ccgaggtggt gcggctgcgc agaagtgaca tcaagcccgc gctcggagcg
    18121 gtgggctcgg cgcccttcgt ggtgggcgtc tatggcgcgc ccgagggccg cgatgcttcc
    18181 gcgcccggtg gcgagcgcct caagctgctg ctggacgtga aggccctgct gctggcggag
    18241 atgctggccg agtccaactc caaccccaac cgacgggtga acggatgagc gaggaggggc
    18301 ggaacgccga ggaggtgcgt taccgggccc tgctggatct ggacgtgtcg cgcccggagg
    18361 cccgagagga actggtgacc ggcctgcacg acgagagctg gcgggtgcgc cgcgcggcgg
    18421 ccgaggggct cgtgcggctg ccggagcgcg gggccgtggt ggagcggctc atcgccgtgc
    18481 tgggcgagcg cgacgagacg ggcgcgcgca acgccgcggc ggagtccctc gcgggcatgg
    18541 gggcctcggc ggtgcagccc ctggtgcacc tgctcggaca cgcggatccg gacctgcgca
    18601 agttcgccgc ggacatcctc ggccagctcg cgctgccgga agcggagggc gcgctggtgg
    18661 ccgtgctgct ggaggatggg gatctcaacg tccgggtggc ggcggcggag gccctgggcc
    18721 gggtgggggg acgcggcgcg gcgttcgcgc tcgagcgcgt gctgtccaac cccgagcccc
    18781 tcctgcgcct gagcgccctg gagtcgctcg cggcgctgcg ccatccgccc ccgctcgccg
    18841 acgtggtgcc cctgctcaac aaccccctgc tcaagcgcag cgcctaccgg gtgctgggcc
    18901 tcatcgagcg caccgaggtc gtggcgctgg tgtgccgggg tctggcggcg tccgagtcgc
    18961 gctccacccg ggaggcggcg ctcgtggcgc tcggccagca ctccgcgcgg atggcggatg
    19021 gcgcgcgtcc cgccatgtac gcggccgtgg gcgaggcgct ccggcggctg ctcggggcgg
    19081 tgagctgggt gacgagcgcg ctggagtccg gagacatcga ggtgaagacc ggcgcgctcg
    19141 tggccgcggc ggccctgcgc gagccccggc tggcgcccct ggtggccgag gtggcccagg
    19201 aggagcggct ggtgcccgag gtcatgcgca cgctcgcgtg cttcggcccg gagacgggac
    19261 gcgagctgct cgcgagcatg gaccggctgt ccttccccgc gcgcgaggcg gccggacagg
    19321 tcctggtgga catggtggac gagtccttcg tgcccgagct cgtccagatg ctcgactggg
    19381 gcgaggtgga tttgaagggc gtggcggcgc gggcgctcgg acgcacgggg gcgctggaag
    19441 ccgtggagcc gctggcgggc ttcctgtcca acccagagct cgccggggtg gccgctcgcg
    19501 cgttggtggc gctgtcggcg ggctttcgcg cgcaggtgct ccaggtgctg cagacgtccc
    19561 tggagcaggg ggctcagccc gtggtgctca acgccctggt gcgcgtgggc ggcacggccc
    19621 agctccccct ggtgcggcgc atcgcccggg aggcgtccgt gcccctgcgt gccaccgccg
    19681 tggaggtgct cgccgcggtg gatccctccg ggggtctgga gctggcgcgc gtggcgctgg
    19741 tggacgaggc cccccgggtg cgtgccgccg cggtgcgggt gctcggccag gtgggggatg
    19801 tctccctggc gccgctgctg caacgggccc tgtcggatga tgcgttggag gtgcggctcg
    19861 ccgccctgga agcggtgggc gagtgcggag cggtggcgct cgcggaggac ctggaggcct
    19921 tggtgcggca tccggatgga gccatcgcct tccgggcggt gcgctcgctg gcgcgcctgg
    19981 gcgtgctgcg cgacgaggtc atccaacacg cggtggccca tgaggaccac gaggtggtga
    20041 aggcggcgct gctggcgggc gcggcctccg ggggcggcga ggccctggca ctgggcctgc
    20101 tcggccatgc ccactgggac gtgcgcgccg cggcggcccg ggtgctggcg gactcccgcg
    20161 aggagcggct gctgccgccg ctgatgaacg cattgctctc cgagacggat gcactggctc
    20221 gtcgggcgct ggtggacgcg gtggaacgct tgtcgggacg ttgagtgaag gggggagggc
    20281 cgcgcgggtg atgcctttcg atacaggcag gccggagatg accgcggagg agttccgcct
    20341 gttgcgggac ttcgtgtatg cctactgcgg catcctggtc cgcgacgaca tgaagtacgt
    20401 catggagcgc cggttgtggc cccggctgga agccctgggc ctgacggatt tcagcaccta
    20461 ctaccgctac ctgcgcttcg acgcccagcg ccgctccgag ctggagacgg ccgtcgaggc
    20521 gctcaccacc cacgagacgt acttcttccg cgagccgcgc cagctcaagg ccttctccga
    20581 ggaggtgttg ccggtgctcg agcgccgcaa cgcgcgctcg cggcgcctgc gcatctggtc
    20641 cgcgggctgc tcgtccgggg aagaggccta caccgtggcc atgctcctct tggagagcgg
    20701 gcgcttcgag gggtgggagc tcgaggtgca cggcacggac atctcccgcc gggtgctcaa
    20761 cgcggcgcgc ctgggcgagt acgggccgag tgccctgcgc tccacgtccg cggacaagct
    20821 cgcgcgctac ttcgtccacg tggggcccaa ccgcgtgcgc gtgcgcgacg acgtgcgcgc
    20881 catggtgtcc ttcgggcacc acaacctgcg cgacgtggac tccgttcccc tggcctcgcg
    20941 cgtggacgcc gtcttctgcc gca
//
