LOCUS       NZ_CP022098            21065 bp    DNA     circular CON 17-FEB-2024
DEFINITION  Cystobacter fuscus strain DSM 52655 chromosome, complete genome.
ACCESSION   NZ_CP022098
VERSION     NZ_CP022098.1
KEYWORDS    RefSeq.
SOURCE      Cystobacter fuscus
  ORGANISM  Cystobacter fuscus
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Cystobacter.
REFERENCE   1  (bases 1 to 12349744)
  AUTHORS   Rupp,O., Goesmann,A. and Sogaard-Andersen,L.
  TITLE     Sequencing and comparative analysis of myxobacterial genomes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12349744)
  AUTHORS   Bruckskotten,M., Treuner-Lange,A., Rupp,O., Goesmann,A. and
            Sogaard-Andersen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2017) Department of Ecophysiology, Max Planck
            Institute for Terrestrial Microbiology, Karl von Frisch Str. 10,
            Marburg, Hessen 35043, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 09-AUG-2016
            Assembly Method                   :: Celera Assembler v. 8.1
            Expected Final Version            :: yes
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/17/2024 10:04:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,093
            CDSs (total)                      :: 10,016
            Genes (coding)                    :: 9,906
            CDSs (with protein)               :: 9,906
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 26 of 110
            Pseudo Genes (incomplete)         :: 101 of 110
            Pseudo Genes (internal stop)      :: 1 of 110
            Pseudo Genes (multiple problems)  :: 17 of 110
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:24:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3916205
            Orig. end                         :: 3937270
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21065
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="19"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21065
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21065
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11065](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11065
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            349..882
                     /locus_tag="CYFUS_RS16125"
                     /old_locus_tag="CYFUS_003188"
     CDS             349..882
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002623475.1"
                     /locus_tag="CYFUS_RS16125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003188"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_095986035.1"
                     /transl_table=11
                     /translation="MSQPSAETLPFLGWVSELARTQVHSLTRIARHEGLSAEDALDAIQ
                     EAFHTYLLLPHARSLSDDHEDSRALLAVLVRNAARNMRRRHHRAMPHEDVDTARELSAP
                     QPTADELLVLAEDHVKLRGCVNKLNQVQRHVVTMRMLEEVSGAEVARELSLTPGHVAVL
                     LHRAKAELQRCVMS"
     misc_feature    1118..1134
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 21.92"
                     /tool="antismash"
     misc_feature    1120..1134
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.69"
                     /tool="antismash"
     gene            1444..3084
                     /locus_tag="CYFUS_RS16130"
                     /old_locus_tag="CYFUS_003189"
     CDS             1444..3084
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002623476.1"
                     /locus_tag="CYFUS_RS16130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003189"
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="WP_095986036.1"
                     /transl_table=11
                     /translation="MSRQIFHADTRSAWFWWRRLLTTATTAVLAAVLSVLAPISAAHAA
                     TGGFHIANGRLLDANGNDFIIRGISHPHAWFQQRTSAFADIKVVGANSVRVVLSGGRWS
                     VNTASDVANVISLCKQNRLICVLENHDTTGYGEQGGAFSLDQAVDYWLSIRSALVGQEA
                     YVIINIGNEPYGNTLYTEWVGATINAIQRLRNAGLTHTLMIDAPNWGQDWSNTMRDNAD
                     TIWAADPLRNSIFSVHMYGVYNTPEKVKAYLDSFTSRGLPILVGEFGWYHSDGDPDEFT
                     LTEYTTLQGLGYMGWSWSGNGGGVEYLDMVTNFDPARRTDWGNWLITSANGLEATSVEA
                     SVFGSSGGDTQPPTVPASLATTGTTANSVSLAWGASTDNVAVTGYDVYRGSSRVATLPG
                     SMLTYTDTGLAANTAYSYKVYARDAAGNVSEASNTVSATTQSSGGGNGGCTATYQFDSE
                     WGSGFGATVTVKNTGTAATKGWTVSWTFGGNQQITNMWNATSTQSGASATARNMSYNGV
                     LQPGSSTSFGFQAAYSGSNAAPTLTCTVN"
     gene            3209..4087
                     /locus_tag="CYFUS_RS16135"
                     /old_locus_tag="CYFUS_003190"
     CDS             3209..4087
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002623477.1"
                     /locus_tag="CYFUS_RS16135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003190"
                     /product="aldo/keto reductase"
                     /protein_id="WP_095986037.1"
                     /transl_table=11
                     /translation="MSSTSSRPAEKSGTFKLGGDLPIHRLGYGAMQLTGPGIWGPPKDR
                     AEAVRVLRRALELGVNFIDTANSYGPYYSEEIIAEALHPYAKGVVVATKAGLVRTGPNQ
                     WHPVGAPKYLRQELELSLRRLKLERIDLYQLHRIDPKVPVEESLGELKALRKEGKIRHI
                     GLSEVSVEEIQRARKVVDIVSVQNRYNLVDRVHEGVLDYCEKENLGFIPWFPLATGGLA
                     KPGSALDSVARKHNATPSQIALAWLLARSPVMLPIPGTSSVKHLEENLVGAEVKLGKEE
                     LAAVDAQASGR"
     gene            4637..7444
                     /locus_tag="CYFUS_RS53925"
                     /old_locus_tag="CYFUS_003191"
     CDS             4637..7444
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="CYFUS_RS53925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003191"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_095986038.1"
                     /sec_met_domain="Pkinase (E-value: 4.4e-43, bitscore:
                     146.7, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKNDSQINPEFTSAYMQELAALPPGRRRIPPSLAARFKDIRLAG
                     EGAMGVVYRAVDPRLGRTVALKLLKNDNPALIQRFLSEARSQARIQHEHVCGVYEAGLA
                     EDEPYIVMQYVDGVPLSRARERMTLEQQVTLLQEVSTAVHEAHRLGMIHRDLKPGNILV
                     EQRADGTWKPYVVDFGLARQVAEQGTTQTGEVLGTPAYMSPEQANGDVRQLDRRSDVYS
                     LGATLYDVIAGRPPYVSEHPWRLLLIAAMEDPPPLGQVKSGVPKNLETIVMKCLEREPA
                     RRYDSARALAEDLRRSLDGEPIWAKPASWGERLRKTVCRNKLLTGVLGALLLWGLGVGT
                     VWVGARRRAAEQARLARELGESVKEMELFLRAAYGLPLHDVERERDVVRARLGEIEQHL
                     RASGDAGLGPGHTALGLGQLALGEPTRAREHLEKALAAGYTSANLEYALGRALGELYRR
                     ALEETRRITQPLERQRRVALLDTSLRQPALLHLRAAMGTRLEVPEYVEGLIALYEGRHD
                     EAIAKAKVAFGKAPWMYEPKKLEGDALYAEGSKYRHDAAFDHEKMKGYFERAEEAYRVA
                     AEMGSSDPAIHRAQCELWEKRGWADYSRDLPPGPAFEAAEAACGRAVRSSSRDGGAVVQ
                     RALVLLARAFVIGANIPGGALPLVEEALETVEAERSARPQDVLAHYAVAQALYLRARLL
                     EGRGGEVSLEPAIAAYQRVLSLEPGFTWAHNELGDVYFQEARRIGARGGEAAPLLEKAV
                     EQYTRALALDPGFALPVGGLLDAAATRLEGEIARKREAPEALQALSHALGQLEKSGATP
                     WVLALWKARAYRLRAHHDLVLGRDPRPVLASLLEVIHAAAGESPTDSWLLKELVLGRVL
                     ESENERLHGRDPAVALERGRALVRKLGEVDGARARETCELATRLSSFPVRECQRFLNSS
                     QASYR"
     gene            7497..8357
                     /locus_tag="CYFUS_RS16145"
                     /old_locus_tag="CYFUS_003192"
     CDS             7497..8357
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS16145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_003192"
                     /product="hypothetical protein"
                     /protein_id="WP_095986039.1"
                     /transl_table=11
                     /translation="MPMWRACRLFIALVVACFVGCGGTAEEWEQGSSLANVEQASGGGI
                     YDRPPPNGLNGTSPSCFWAHGTQQALRSMGSAALDQGAGFLPSFPLNLVSESCRHVFRS
                     AVECALTPAQSVRDPVTGALYTGWWGLAPSWLGDVLDTAGRRYVTACMVQRLNFYGASV
                     PILFEGAHPAIAHSTTYASQYPIEESTVFGDLFSSSTPLLGLLPAFNVFVCWESLLPQS
                     CGLLGLPLLEKRICDDAPLCGLLPVGPCALSCEGSGPYWKCRPFLLAPLWTETVRVKLE
                     TSSCQ"
     misc_feature    8463..8477
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.87"
                     /tool="antismash"
     misc_feature    complement(8473..8487)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.81"
                     /tool="antismash"
     misc_feature    complement(8474..8487)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.45"
                     /tool="antismash"
     misc_feature    8586..8601
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.65"
                     /tool="antismash"
     gene            8619..10001
                     /locus_tag="CYFUS_RS16150"
                     /old_locus_tag="CYFUS_003193"
     CDS             8619..10001
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002623481.1"
                     /locus_tag="CYFUS_RS16150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003193"
                     /product="cytochrome P450"
                     /protein_id="WP_095986040.1"
                     /sec_met_domain="p450 (E-value: 4.2e-93, bitscore: 311.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTVTPLPTATAPEVPGGLPLLGHALRLLRLPIAYLQSLREFGDI
                     VQLRIGSSPVYVVTSPEFIHQVLVTHADSFERGRVFDKATAAIGKGLIVSNGTFHRQQR
                     KLLQPGFHRPRIHGYMEIIHRQAEAQIAGWSPGARISLREEMHRLTLNAVTRTLFGANT
                     EERIAAEIGDYIDAANSWVGLHTVLPGRFFERLPMPVNRAFERKKARFDEIINTFIESR
                     RADGRDQGDLLSALLASQDDETGKGMSDEQLRMEIAGLFVAGSETTATALTWLFHEVGR
                     HPEVEARIHAEVDAVLGGRPVTTEDLPRLQYIQSVISETLRRYPIAWLLMRRATRDVEL
                     AGTLLPAGAEVIVSPMMVHRNPQLYPEPLRFDPDRWLPERARELPRHAFLPFGDGKHKC
                     IGDYFARTEMVIAVATIAARWRLVPVPGHRVWEVPRSVLRPNQVLMTAVPRSAAPVPEE
                     NH"
     gene            10001..11065
                     /locus_tag="CYFUS_RS16155"
                     /old_locus_tag="CYFUS_003194"
     CDS             10001..11065
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002623482.1"
                     /locus_tag="CYFUS_RS16155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003194"
                     /product="terpene synthase"
                     /protein_id="WP_232537600.1"
                     /sec_met_domain="T1TS (E-value: 1.2e-59, bitscore: 202.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDTQRAAIEFHFPFPRDLSPDIEQAQRHSIAWARQMGLATTDTA
                     LRYLEAWNWGRLTGHCLPTARGANLDLATDWMTWGFLYDDQFAGPLGNQPDRVARITEN
                     MIGVLHATSATPSDDACARGITDILQRLSSKMSPAWMARFRDDLKWFFIGVLRMTTYRN
                     HLSQIDTRTAFEIRRLDISMDAVIDLIEVAEGFEVPEVLFGTTQIQALRQCVIDIVILQ
                     NDVFSLPKDRHQQEVNVILAMERSENLTTAQALARTSALVDEKVQEFLTVKASMPALYE
                     TLGLGATDRAHMDRYIHCLELMIHGCVYSHAECVRYSTRSEHTQPIAGRGFIQDLHLGA
                     GIERAQAIVRTIQG"
     gene            11127..12425
                     /locus_tag="CYFUS_RS16160"
                     /old_locus_tag="CYFUS_003195"
     CDS             11127..12425
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1102: glycosyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF018434.4"
                     /locus_tag="CYFUS_RS16160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003195"
                     /product="glycosyltransferase"
                     /protein_id="WP_095986041.1"
                     /sec_met_domain="MGT (E-value: 2.5e-34, bitscore: 118.4,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKITVLVLGTRGDVQPFIALAIALQRRGHEVCVATSRSFADMVAH
                     SGVRYVPVSADYEEWFQSEEGIRWMAGSDNTARFMRMLAGEGVGIDSRLKPRMHRELLA
                     ACEGTDAIVANLVIEDSAACIAEKLEVPFIPGYTMPMLPTSEFPSPFISERKLPLRAMN
                     RLTHTLLETFYWQGQKRLIHAWRAELGLPPTAISMREKLWRAGTPILHCYSSHLVPRPS
                     DWSAANVITGPWMMPPDVRASAGGAPSSELIRWLDQGPPPIYLGYWRLPSMDKAGMVRL
                     AIEVANTLGVRFAIGASWSAEEIAALRVPESIFITRSVDHDWLFARCSATVHHGGAGTT
                     AATLRAGLPTVICSICNDQPFWGNRVTALGVGYSMPFKQLTAARLTQALRHIQDGAVRD
                     RANRLGELMRREDGTATAVRIIEERVPGAPLRS"
     gene            complement(12437..13315)
                     /locus_tag="CYFUS_RS16165"
                     /old_locus_tag="CYFUS_003196"
     CDS             complement(12437..13315)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015998.4"
                     /locus_tag="CYFUS_RS16165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003196"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_095986042.1"
                     /transl_table=11
                     /translation="MSLRDYDNISPTARLVAEMRRHSDIPFAEEIATRIGSAQLVREML
                     DGDAPAPELLSWMAPTLEARYKCLETALKTAGIKQIVELGSGFAFRGDAMSRTHPLRYI
                     ETDLPEMHETRLRLHDELRRDGVLPAQENVVFAPLNAVAPEDAAVLEQHLVPGEPVAVI
                     HEGLLQYFTRDEKRATAQLIAGLLKRHGGVWLTPDFELNDDDSRKQWTHPHFARIFSVI
                     ARSTQSNLRDTTFTRVDEVKDFFSKLGFRVTPRAQIDGTFALSSAERVGTTPEQLDILR
                     RSRILWELRLD"
     misc_feature    complement(13330..13346)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.09"
                     /tool="antismash"
     gene            13456..15126
                     /locus_tag="CYFUS_RS16170"
                     /old_locus_tag="CYFUS_003197"
     CDS             13456..15126
                     /EC_number="3.5.1.4"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002623489.1"
                     /locus_tag="CYFUS_RS16170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003197"
                     /product="amidase"
                     /protein_id="WP_095986043.1"
                     /transl_table=11
                     /translation="MKKPSPSSGTPRELSRRTFLGGAAVASTLVALDVQAQPSANSTPP
                     AAPRGSAFELEEATLAGLQADLSLGKYTAHGLTEHYLARIQEIDKGGTALGSVIELNPD
                     ALAIAAALDAEREAKGPRGPLHGIPVLIKDNIGTADKMQTTAGSLALVGAVPSRDAFVV
                     ERLRAAGAVILGKTNLSEWANFRSTHSCSGWSGRGGQCRNPYALDRTPSGSSSGSGAAT
                     AANLCAVSVGTETDGSIVSPSAACSLVGLKPTVGLVSRSGIVPLSHTQDSAGPMTRTVT
                     DAAVLLGVLAGVDPRDAVTAASQRHAHADYTRFLDVNGLKGARIGVPRERFFGYHPATD
                     ALIERALDVLKARGAELIEAPIPSAAKLDEPELEVLLHDFKADIEAYLAGLGERTRLKT
                     LADLIRFNEEHRDTELAWFGQELFHQAQEKGPLTDKKYRKALEACRKLSREQGIDAVMA
                     KHELDALVAPTQAPPGLIDLVNGDHWLGSSSTPAAVAGYPSITVPAGYIAGLPVGLSFI
                     GKAWSEPTLLRLAFAYEQATKHRRPPMFAPTADLRPAKV"
     gene            complement(15908..16684)
                     /locus_tag="CYFUS_RS16180"
                     /old_locus_tag="CYFUS_003199"
     CDS             complement(15908..16684)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS16180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_003199"
                     /product="hypothetical protein"
                     /protein_id="WP_157758471.1"
                     /transl_table=11
                     /translation="MTAAARMARDLVQGTARAWIRELPACPQLPALLVRAQRFLPGSAE
                     QATNVILQSLVPKLTALTNEIWNHASGALNPAAATPGRKSDKHVHKFLYGLFDLIAATD
                     GHRLDDQDLFHAHLVRVDVAGGGVARTQDVGLFFHAKEFPTNLDPRAALRDVNGRASQQ
                     FNSAVAGFANRNYIWLLSQNKLWCISGDVTDVGHADFTAVLFPADEAPDRTNFIYDDRI
                     AGRALKQDLFGTEVAGVNYFPNHIRGGHKHRKVFFK"
     gene            16987..18072
                     /locus_tag="CYFUS_RS16185"
                     /old_locus_tag="CYFUS_003200"
     CDS             16987..18072
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS16185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_003200"
                     /product="hypothetical protein"
                     /protein_id="WP_095986046.1"
                     /transl_table=11
                     /translation="MTINVKNRPAPRTLNTTSTQAPAKSTPTAKSDAANGTAGASPSPQ
                     VQPQKPSASAPPSYHQDQLGKPKAPAQAPSGNAVFQSRQDIATLNSRRGSVFSTRPAQG
                     TSASSAPLATSARQAPAKFQQLATTHQAEITAWSDQANNPTIQNSSEKGGVCAAMVNEW
                     ARAGSAGPQQEADFRKRLNDGDTQHFVDLQRTSRQKHEQFIKNDDFLESHPIANHLKSD
                     VRNELKAENDKHNQTMNVAGFKPEDMLFPATKRINSNEHLAEMVSGAMQTAKPLVPEGT
                     SFFAKMMVTDKNQTGGHAIGVKMTHLPGGKMEYSMLDPNTGEFSKIPEQNLKNFMTDHM
                     NKTYGKDYVGGGLSLHAMMPG"
     misc_feature    complement(17027..17041)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.21"
                     /tool="antismash"
     gene            complement(18216..18575)
                     /locus_tag="CYFUS_RS16190"
                     /old_locus_tag="CYFUS_003201"
     CDS             complement(18216..18575)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002623502.1"
                     /locus_tag="CYFUS_RS16190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003201"
                     /product="DUF1330 domain-containing protein"
                     /protein_id="WP_198316590.1"
                     /transl_table=11
                     /translation="MIAFNPADLDRFLREDDGAPVVMLNLLRFRPDGGRERYLKYLQMA
                     GPLVARYGAEILYAGDGMTPLAAEPGQAWDTVALVRYPSRRAFANMIADPEYAVADPVR
                     MSALSEAVLQPTRSI"
     gene            complement(18590..18979)
                     /locus_tag="CYFUS_RS50615"
                     /old_locus_tag="CYFUS_003202"
     CDS             complement(18590..18979)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024092.4"
                     /locus_tag="CYFUS_RS50615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003202"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_198316591.1"
                     /transl_table=11
                     /translation="MTEQVAMTDFRVAAYEKFLSAWSAIPDDRRLQLLHASVTEGIVFT
                     NPTKPRTGIDDLADHLRAFQTRSPGGSFRLVAMLGWEDNAIATWQFVDAAGNAGFTGYD
                     VVAFDGEHRIKSILLFSNVPQQTLK"
     gene            19106..20041
                     /locus_tag="CYFUS_RS16195"
                     /old_locus_tag="CYFUS_003203"
     CDS             19106..20041
                     /GO_function="GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.4"
                     /locus_tag="CYFUS_RS16195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_003203"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_198316592.1"
                     /transl_table=11
                     /translation="MSAIDFEVSVPQLRCFIAVVDAGSVAEAGRRLGMSAASVSKAITR
                     LEEGAGVRLLHRSTHALSLTEAGEALLEPAREAVRAAEAFEDAAGHARGSGDAGVVRLT
                     AAVGFVRHVLVPMLGELARLHPEIQLDVRATNEVLDLADDGIDLAIRSGSLVGLPGHIH
                     QTWFTCPWVICAAPSYLARRPAPRTISELDEHDLIRFRNPQSGQIQPWPHRTVAGTTGG
                     TYEPRARFAFDDGGAVWGTMLAGGGIACVPLYIAAASLRNGAAVELLADFRGAAATVVM
                     LRRDRRLTPGRLSTLMAFLSARAPDFSDLL"
ORIGIN
        1 aggcctccaa tccacagcag gaccgtcacc aggcccagcc gcaacatcgt cattccgaac
       61 cgctcggctc cagcggccaa tctcaacacc cgctcgaatg cgtacatacc gtgcactcct
      121 cgttgtccgc ggacgggcac ggaggtgcca gcgtgtgcgg actcgagggg ataggtcgcg
      181 accgcggcgg gaattacacg gccggatcca ccgtgccctt tttccgtcct gctgctcgag
      241 tcggcttctc gcgacaacca tgttgacacc caccgcctcg cgtgcaacgc gtctcgggct
      301 cgcgcgtctc cttcgccagt cacccccctt cctatctgac gagtttccat gagccagcct
      361 tcagcagaaa cccttccctt cctcggttgg gtatccgaac tcgcgcggac gcaggtgcac
      421 tccctgacgc gcatcgctcg ccacgaaggg ctgtccgccg aggatgcgct cgatgccatc
      481 caggaggcct tccacaccta cctcctgctg ccccacgcac gctccttgtc ggacgaccac
      541 gaggattcgc gggcattgct tgcggtgttg gtgcgcaacg cggcgcgcaa catgcgccgg
      601 cgccaccacc gcgcgatgcc ccacgaagac gtggacacgg cgcgggagct ctccgcgccg
      661 cagcccacgg cggacgagct gctcgtgctc gccgaggacc acgtgaagct ccggggctgc
      721 gtgaacaagc tcaaccaggt gcagcgtcac gtggtcacga tgcgcatgct ggaagaggtg
      781 agcggcgcgg aggtggcgcg cgagctctcc ctgacgccgg gtcacgtggc cgtgctgctg
      841 caccgggcga aggcggagtt gcaacgctgc gtgatgtctt gacgcggtgt tccacctccc
      901 tggcgaggcc acggctccat ctgctgaatc gctttcctgc ctccgaggaa ctgtcctgca
      961 tccgacatgt tctggaagag gcggtttcgc ttgaatttct ccacaatctg gtttcagtta
     1021 gtgtcattgt tgcttcgcgt ctgatggggc ggactcagcg gtagcgcccc cccaatccca
     1081 cgaatccatc tggaggatgc gcttcactgc cacaagactg gaattttcct tcaaccaaaa
     1141 atgacaacgt tacgattcgt ttccaccccc cttgtgtccg cgcgggagtc ctcggactgc
     1201 catcagactg gaatatttcc atcggccaaa aatgacaacg ttgcgattcg ctgaccccct
     1261 cttgtgaccc gtggagcagc actgggaacg atgaagggct taccccaggg agaggaagaa
     1321 caatgctgtc aatcattgca gacccatggc gggtccatgc ctgccattgg gcgtcgggct
     1381 gatctggaaa ccgccgaagt cgtggatcac atctcaatca cttgcttctg gagacaccta
     1441 cccatgtccc gacagatttt ccatgctgat acccgtagtg cctggttctg gtggcgaagg
     1501 ctcctcacca ccgcgacgac cgcggtgctg gccgctgtac tctccgtcct cgcgcccatc
     1561 agtgccgccc atgccgccac cggcggcttc catatcgcca atggccggct cctcgacgcg
     1621 aacggcaacg acttcatcat ccgcggtatc agccacccgc acgcgtggtt ccagcagagg
     1681 accagcgcgt tcgctgacat caaggtggtg ggggcgaaca gcgtccgtgt cgtgctgagc
     1741 ggtggccggt ggtcggtcaa cacggccagc gacgtggcga acgtcatctc gctctgtaag
     1801 cagaaccggc tcatctgcgt gctcgagaac cacgacacga cgggttatgg ggagcagggt
     1861 ggcgccttca gcctcgatca ggccgtcgac tactggctga gcattcgcag cgcgctcgtt
     1921 ggccaggagg cctacgtcat catcaacatc ggcaatgagc cgtatggcaa caccctctac
     1981 acggagtggg tcggggcgac catcaatgcc atccaacgcc tgcgcaacgc tgggctgacg
     2041 cacaccttga tgattgacgc gccgaactgg gggcaggact ggtccaacac catgcgggac
     2101 aacgccgata cgatctgggc ggccgacccg ctgcgcaact ccatcttcag cgtccacatg
     2161 tacggcgtct acaacacccc ggagaaggtc aaggcctacc tcgactcgtt caccagccgg
     2221 ggcctgccca tcctcgtcgg cgagttcggg tggtaccact ccgacggtga tccggatgag
     2281 ttcacactca cggagtacac cacgttgcag gggctcggct acatggggtg gtcgtggagc
     2341 ggcaacggag gtggcgtcga gtacctcgac atggtcacca acttcgaccc ggccagacgc
     2401 acggactggg gcaactggct catcacgagt gccaatggcc tcgaggccac ctccgtcgag
     2461 gcctcggtct tcggcagcag tggtggcgac acgcagcccc cgaccgtgcc cgccagcctg
     2521 gcgacgacag gcacgacggc gaacagcgtg tcgctcgcgt ggggcgcctc gacggacaac
     2581 gtcgcggtga ccggttacga tgtctaccgc ggatcctccc gcgtggcgac gctccccggc
     2641 agcatgctga cgtacacgga cacggggctg gcggcgaaca cggcttacag ctacaaggtg
     2701 tatgcgcgtg atgccgctgg gaacgtgagc gaggcgtcca acacggtttc cgcgacgacc
     2761 cagtcctccg ggggaggaaa cggtggctgc acggcgacct accagttcga tagcgagtgg
     2821 ggctctggct tcggcgccac cgtgacggtg aagaacaccg ggaccgccgc gaccaagggc
     2881 tggacggtca gctggacctt cggtggcaac cagcagatca ccaacatgtg gaacgccacg
     2941 tcgacccagt ccggcgcgag cgccacggcg cggaacatga gctacaacgg tgtcctccag
     3001 ccggggagca gcacgtcctt cggcttccag gcggcgtatt ccggttccaa cgccgcgcca
     3061 accctgacct gcacggtcaa ctgatgcagc cggtggctgg gagggctcga ggtggggtcc
     3121 ctcccggccc ggtcccgggc gtcccgcgcc gaaacgcgct tcctgcatat gcatctactc
     3181 cggcattcac agcacggagg aagaacccat gagcagcacc tcatcgcgtc ccgcggagaa
     3241 gagtggcacc ttcaagctgg gcggcgacct gcccatccat cgtctgggct acggcgccat
     3301 gcagctcacc ggccctggca tctggggtcc gcccaaggac cgagcggagg cggtgcgcgt
     3361 gttgcgccgc gcgctggaac tgggagtgaa cttcatcgac acggcgaact cctacggccc
     3421 ctactacagc gaggagatca tcgcggaggc cctgcacccg tacgccaagg gcgtggtggt
     3481 ggcgaccaag gcgggcctgg tgcgcacggg gcccaaccag tggcacccgg tgggcgcgcc
     3541 gaagtacctg cgccaggagc tggagctgtc gctgcgccga ctgaagctgg agcgcattga
     3601 cctgtaccag ttgcaccgca tcgatccgaa ggtgccggtg gaggagtcgc tgggtgagct
     3661 gaaggcgctg cggaaggagg ggaagatccg ccacatcggc ctgtcggagg tgtcggtgga
     3721 ggagatccag cgggcgcgca aggtggtgga catcgtgtcg gtgcagaacc gctacaacct
     3781 ggtggaccgc gtgcacgagg gggtgttgga ctactgcgag aaggagaacc tgggcttcat
     3841 cccctggttc ccgctggcga cgggcggcct ggcgaagccg gggagcgcgc tcgactccgt
     3901 ggcgaggaaa cacaacgcga ccccctcgca gattgccctc gcctggctgc tggcgcgctc
     3961 gccggtgatg ctgcccatcc cgggcacgtc ttccgtgaaa cacctggagg agaacctggt
     4021 gggcgcggag gtgaagctcg gcaaggagga gctggccgcc gtggacgcgc aggcgtcggg
     4081 ccgctgagcc aggtccgcca cttccgcttc acgtatcgcg ggaggagcgt cacctcgttg
     4141 acgcccaccc gcttgggcag gtccagctcc tcacccaacg ccttgtcacc aaccccggtg
     4201 gcctacgcgg cctgctcggc tggcatggtg ttgagttgaa tgcagcgggg tgccccacag
     4261 ggcaatcccc cttccgtccc atacgcatcc aggtccgcga tggatggccc cctggcgtcc
     4321 tccggcgcga agaacagcac ccgcttctcc tgctcggcgg ccgcgcttcg gcgaggcgcg
     4381 cgaaaacagg aacgggcaac ccaggaggct cataccgaat tcagaatcca gacagtgtcg
     4441 ggtgctgctc acggcccagc agtcagcctt ccgacaatcc atgtaaaaca cgatattccg
     4501 ataggggttt ggtgccatcg tcgattcagt gagttgctta tggggccccc gtgagggggc
     4561 ctatctcggt ccttcttcgc ccgcccaggc gcttgtcgtt ccttttgggc aggaagagcc
     4621 gcctcctgag tcccccatgc agaagaatga cagtcaaatc aatcctgagt tcacctcggc
     4681 ctacatgcag gagttggccg cgctcccacc cgggcgccgg aggattcccc cgtccctggc
     4741 cgcgcggttc aaggacatcc gcctggcggg tgagggcgcg atgggggttg tctaccgggc
     4801 ggtggatcca cggttgggcc gtaccgtcgc gctgaagttg ctcaagaatg acaaccccgc
     4861 gctcatccag cggttcctct cggaggcgcg ttcccaggcg cgcatccagc acgagcatgt
     4921 gtgtggggtg tacgaggccg ggctggcgga ggacgagccg tacatcgtga tgcagtacgt
     4981 cgacggggtg ccgctgtcgc gcgcgcgcga gcgcatgacg ctcgagcagc aggtgacgct
     5041 gctccaggag gtttccacgg cggtgcacga ggcacatcgc ctggggatga tccatcggga
     5101 tctcaagccg gggaacatcc tcgtcgagca gcgcgcggac gggacgtgga agccctacgt
     5161 cgtggatttc ggcctggcgc gccaggtcgc cgagcaggga acgacccaga cgggagaggt
     5221 tctcgggacg ccggcctaca tgtcgcccga gcaggccaat ggagacgtgc gccagctgga
     5281 ccgccgctcg gacgtgtact cgctgggggc cacgctgtac gacgtgatcg ccggacggcc
     5341 gccctatgtc tcggagcacc catggcgatt gctcctgatc gcggccatgg aggatccgcc
     5401 cccgctgggt caggtgaagt cgggcgttcc gaagaacctc gagaccatcg tgatgaagtg
     5461 tctcgagcgg gagccggcgc gccgctatga ctccgcgcgg gcgctcgcgg aggatctgcg
     5521 gcgctccctg gacggcgagc ccatctgggc gaagccggcc tcctgggggg agcgcctccg
     5581 gaagacggtg tgcaggaaca agctgctcac gggggtgctc ggggcactcc tgctgtgggg
     5641 gctcggggtg ggcaccgtct gggtaggagc ccggcggcgt gccgcggagc aggcgcggct
     5701 cgcccgggag ctgggcgaga gcgtgaagga gatggagctg ttcctgcgcg cggcgtatgg
     5761 gctgccactc catgacgtgg agcgggagcg ggacgtggtg cgcgcccggc tcggcgagat
     5821 cgagcagcac ctgcgcgcct cgggagacgc cggactgggg cccgggcaca ccgcgctcgg
     5881 attggggcag ctcgcgctgg gtgagcccac tcgggcccgg gagcacctgg agaaggcact
     5941 cgcggccggg tacacgtcgg cgaacctcga gtatgcgctg gggcgggcgc tcggagagct
     6001 gtaccggcgc gccctggagg agacccggcg catcacccag ccgctggagc gtcagcggag
     6061 ggtggcgctg ctggacacgt ccctgcgcca gccggcgctc ctgcacctgc gggcggccat
     6121 ggggacacgg ctcgaggtgc ccgagtacgt ggaggggctg atcgcactgt acgagggccg
     6181 ccacgacgag gcgatcgcca aggcgaaggt ggctttcggc aaggcgccct ggatgtacga
     6241 gccgaagaag ctcgagggtg atgcgctgta tgccgagggc agcaagtacc ggcatgacgc
     6301 ggcgttcgac cacgagaaga tgaagggtta tttcgaacgg gccgaggagg cgtaccgggt
     6361 ggcggcggag atgggcagca gcgatccggc catccaccgg gcgcagtgcg agctgtggga
     6421 gaagcggggg tgggcggact actcgcgaga cctcccgccc ggtcccgcgt tcgaggccgc
     6481 cgaggcggcc tgtggccgcg cggtgcgctc gagctcgagg gacggaggcg ccgtggtgca
     6541 gcgggcgctc gtgctgctgg cgcgggcctt cgtgattggc gccaacatcc cggggggtgc
     6601 gctccccctg gtggaggagg cgctcgagac cgtcgaggcg gaacggagcg ctcgccccca
     6661 ggatgtcctg gcccactacg ccgtggctca agccctctac cttcgggctc ggctcctgga
     6721 ggggcggggc ggtgaggtgt ccctggagcc ggccatcgcg gcgtaccagc gggtgctttc
     6781 cctggagccg ggcttcacct gggcccacaa cgagctgggg gatgtgtatt tccaggaggc
     6841 caggcggatt ggcgcgcggg gaggggaggc ggcgccgctg ctggagaagg cggtcgagca
     6901 gtacacgcga gccctggcgc tcgatcccgg cttcgccctg cccgtgggcg gtctgctgga
     6961 tgccgcggcg acccggctgg agggggagat cgcccggaag cgagaggcac ccgaggcgct
     7021 ccaggcgctc tcccatgctc tgggccagct ggagaagtca ggcgccaccc cgtgggtcct
     7081 cgccctgtgg aaggcgcgcg cgtaccggct ccgtgcccac catgacctgg tgctgggcag
     7141 ggatccccgt ccggtgttgg cgtcgctcct cgaggtgatt cacgccgccg cgggggagtc
     7201 gccgacagac tcctggctgt tgaaggagct ggtcctgggc cgtgtcctcg agtcagagaa
     7261 cgagcggctt catggacggg atccggcggt ggccctggag agggggcggg ccctggtgcg
     7321 gaagctgggc gaggtggatg gggcgcgggc cagggagacc tgcgagttgg cgacccgatt
     7381 gagttcattc ccggttcggg agtgtcagcg tttcttgaac tcgtcccagg cgtcctaccg
     7441 atagcaccag gacacggtgc ggccattccc aatcgcatca cccattggag gttcacatgc
     7501 ccatgtggcg cgcatgtcgt ctgttcattg ctctcgtcgt ggcttgtttc gtcggatgcg
     7561 gcggtaccgc ggaggagtgg gagcagggct cgtccctcgc gaatgtcgag caggcgtcgg
     7621 gtgggggtat ctatgatcgc cccccaccca atggtttgaa tggcacgtcc ccttcctgct
     7681 tctgggcaca tgggacccag caggcgctcc ggtccatggg gagcgccgcg ctcgaccagg
     7741 gggcgggctt cctgccgagc ttccccttga acctggtctc cgagtcctgc cggcacgtgt
     7801 tccgctccgc ggtcgagtgt gcgctcacgc cagcgcagtc cgtgagagat cccgtgacgg
     7861 gcgcgctgta cacggggtgg tgggggctcg cgccctcgtg gctgggcgac gtgctggata
     7921 ccgcgggccg ccggtatgtg acggcgtgca tggtccagcg gttgaacttc tatggcgcct
     7981 ccgttcccat cctgttcgag ggcgctcatc ccgccatcgc gcacagcacg acctatgctt
     8041 cccagtatcc gatcgaggag tcgaccgtct ttggcgacct cttctcctcc tccacgcccc
     8101 tgctgggcct gttgcccgcc ttcaacgtct tcgtctgctg ggagtccctg ttgccccagt
     8161 cgtgtggtct gttgggactg ccgcttctcg agaagcggat ttgcgacgac gcgccgctgt
     8221 gtggcctcct gccggtgggt ccgtgtgcac tgtcctgcga ggggtcgggg ccctattgga
     8281 agtgccgacc gttcctgctc gctccgttgt ggacggagac ggtgcgggtg aagctggaga
     8341 cctccagctg tcagtgagcc cacccggttg ccatgcgcgg aaaaggaatg gggattccgt
     8401 cgaggacagg gggctggagc atggcacttg ctcgcccttt ggtccggagc cctgtcaacc
     8461 ggttttttca gtaatctatt gaaaactcgc gttgcctgcc agccgggaat ccgttaggag
     8521 caacgttgcc tcccccaggc gttcctcacc gagcttcttc tcacccgatg ccggccatgg
     8581 ccgctattgg gaatcattca gcgaggagtg ttcctcccat ggacaccgtg acccctctgc
     8641 ccactgccac cgccccagag gtgccaggtg ggttgccgct gcttggccat gcgctccggt
     8701 tgctgcgctt gcctatcgcc tatctccagt cgttgcgtga gttcggtgac atcgttcagc
     8761 tccgcatcgg ctcgtcgccc gtgtatgtgg tcacctcccc ggagttcatc catcaggtgc
     8821 tggtcactca cgccgacagc ttcgagagag ggcgcgtctt cgacaaggcg acggccgcga
     8881 ttggcaaggg gctcatcgtc tccaacggaa ccttccaccg gcagcaacga aagctcctgc
     8941 agccggggtt ccaccggcct cgcatccacg gctacatgga gatcatccat cggcaagccg
     9001 aagcgcagat cgccgggtgg tcgccggggg cccgcatctc gctgcgtgag gagatgcatc
     9061 ggctgacgct caatgccgtc acccggacac tgttcggcgc gaacaccgag gagcgcatcg
     9121 ccgccgagat cggcgactac atcgacgccg ccaactcgtg ggtgggtctc cacaccgtgc
     9181 ttcctggccg cttcttcgag cggctgccga tgccggtcaa ccgcgccttc gagcgcaaga
     9241 aagcccgctt cgacgagatc atcaatacgt tcatcgaatc gcggcgcgcg gatggccgcg
     9301 accagggaga tttgctgtcc gcgttgttgg cgtcacagga tgacgagacc ggcaagggga
     9361 tgagcgatga acagctccgg atggagatcg ccggcctgtt cgtcgccggg tccgagacca
     9421 cggcgaccgc gttgacctgg ctcttccacg aagtgggacg ccaccccgag gtggaagcgc
     9481 ggatccacgc cgaggtggac gccgtgctgg gtggcaggcc cgtcaccacg gaggacctgc
     9541 cccggttgca atacatccag agcgtgatct ccgagacgct gcgtcgctat ccgatcgcct
     9601 ggctgctgat gaggcgcgcc acccgtgacg tggagctggc gggcaccctc ctgccggccg
     9661 gggccgaggt catcgtcagc ccgatgatgg tccaccgcaa cccccagctc taccccgagc
     9721 cgttgcggtt cgaccccgat cgctggctgc cggagcgggc gcgggagctt ccacgccacg
     9781 ccttcctccc cttcggggac ggcaagcaca agtgcatcgg tgactacttc gcccgcaccg
     9841 agatggtgat cgccgtcgcc accatcgccg cgcggtggcg tctcgttccg gtgcccggtc
     9901 accgcgtctg ggaggtcccc cgctcggtct tgcgacccaa ccaggtcctg atgaccgccg
     9961 ttccccgttc cgccgcaccc gtccccgagg agaaccactg atgattgaca cccagcgtgc
    10021 cgcgatcgag ttccactttc cgttccctcg cgacctcagc cccgacatcg aacaggccca
    10081 gcgtcacagc atcgcctggg cccgtcagat gggattggcc accaccgaca ccgcgctccg
    10141 gtatctggag gcgtggaact ggggccgtct caccggtcac tgtctgccca ccgcgcgcgg
    10201 tgccaacctg gacctggcca ccgactggat gacctggggg ttcctctacg atgaccagtt
    10261 cgctggcccc ctcggcaacc agccggatcg ggtggcgcga atcaccgaga acatgattgg
    10321 cgttctccac gccacgtccg cgaccccgag cgacgacgcc tgcgcgcggg gcatcacgga
    10381 catcctccag cggctctcct cgaagatgtc cccggcctgg atggcccgct tccgcgacga
    10441 tctgaagtgg ttcttcatcg gggtgctgcg gatgaccacc taccgcaacc acctcagcca
    10501 gatcgacacg cggaccgcgt tcgagatccg ccgcctcgac atcagcatgg acgccgtgat
    10561 cgatctcatc gaggtcgcgg aggggttcga ggtgcccgag gtgctctttg gcaccaccca
    10621 gatccaggcc ctgcgccagt gcgtcatcga catcgtcatc ctgcagaacg acgtcttctc
    10681 cctgcccaag gaccggcacc agcaggaagt caacgtgatc ctcgccatgg agcgctcgga
    10741 gaacctcacc acggcccagg ccctggcgcg cacctccgcc ctggtcgatg agaaggtcca
    10801 ggagttcctc accgtcaagg cctccatgcc cgctctctac gagaccctcg ggctgggtgc
    10861 caccgaccgt gcccacatgg accggtacat ccactgtctc gagctcatga tccacggctg
    10921 tgtctattca catgccgagt gtgttcgtta ctccacccgg tccgagcaca cccaacccat
    10981 cgccggccga ggcttcatcc aggacctgca cctgggcgcg ggcatcgagc gggcgcaggc
    11041 gatcgtccgg acgatccagg ggtgagcccc tgacgggccg cgcgagcgcc gtcctcgcgc
    11101 ttcgcgggcg ctgaaaggaa cgagcgatga agatcaccgt gttggtattg gggacgcgtg
    11161 gggacgtgca gcccttcatc gcgctggcga tcgccttgca gcgccgcggt cacgaggtct
    11221 gtgtcgccac gtcccgcagc ttcgccgaca tggtcgcgca cagcggtgtc cggtatgtcc
    11281 ccgtctcggc ggattacgag gagtggttcc agtcggagga gggcatccgg tggatggccg
    11341 gctccgacaa cacggccagg ttcatgcgga tgctggccgg ggaaggggtg gggatcgaca
    11401 gcaggctcaa gcctcgaatg caccgcgagc tcctggccgc ttgcgagggc accgacgcca
    11461 tcgtcgcgaa cctggtgatc gaggacagcg ccgcctgcat cgcggagaag ctcgaggtgc
    11521 ccttcatccc cgggtacacc atgccgatgc tgccgacatc ggagttcccc agcccgttca
    11581 tctccgagcg caagctgccg ctgcgcgcga tgaatcggct cacgcacact cttctcgaga
    11641 cgttctactg gcaggggcag aagcgcctca tccatgcctg gcgtgcggag ctcgggctgc
    11701 cgccaacggc catctcgatg cgggagaagc tgtggcgcgc cggaacgccg atcctccatt
    11761 gctacagcag tcatctcgtt ccgcgtccgt ccgactggag cgccgcgaat gtcatcaccg
    11821 gcccctggat gatgcccccg gacgttcgcg ccagcgcggg cggcgcccca tcgtcggagc
    11881 tcatccgctg gctggaccag gggccaccgc ccatctacct gggttactgg cggctgccct
    11941 cgatggacaa ggctgggatg gtgcgtctgg cgatcgaggt cgcgaacacg ctgggcgtcc
    12001 gcttcgccat cggagcgagc tggagcgcgg aggagatcgc ggcgctccgg gtgcccgaga
    12061 gcatcttcat cacgcgctcc gtggaccacg actggctgtt cgcgcgttgc agcgcgaccg
    12121 tccaccacgg cggcgcgggc acgaccgcgg ccacgctacg tgccgggctg ccgacggtca
    12181 tctgctcgat ctgcaatgat cagcccttct ggggaaaccg ggtgacggcg ctcggggtgg
    12241 gttacagcat gccgttcaag caactcaccg cggcgcggct cacccaggcg ctgcgccaca
    12301 tccaggacgg cgcggtgcgc gatcgggcga acaggctggg agagctgatg cggcgggaag
    12361 atggcaccgc cacggcggtc cgcatcatcg aggagcgtgt accgggcgcc cctctgcgct
    12421 cttgaggtga tcggcgtcag tccaggcgca gctcccacag gatgcggctc cggcgcagga
    12481 tgtcgagttg ctccggggtc gtgccgacgc gctccgcgga ggagagtgcg aaggtgccgt
    12541 cgatctgcgc acggggcgtg acgcggaagc ccagcttcga aaagaaatcc ttcacctcgt
    12601 ccacgcgggt gaaggtcgtg tcgcgcaggt tgctttgggt ggagcgggcg atcaccgaga
    12661 agattcgcgc gaagtgggga tgggtccatt gcttccgtga gtcgtcgtcg ttcaactcga
    12721 agtccggggt cagccagact ccgccgtggc gcttcaggag cccggcgatc agttgggccg
    12781 tcgcccgctt ctcgtcccga gtgaagtatt ggagcaaccc ctcgtgaatc acggccaccg
    12841 gttcgcccgg gacgaggtgc tgctccagga cggcggcgtc ctcaggcgcc accgcgttca
    12901 agggcgcgaa gaccacgttc tcctgggctg ggagcacgcc gtcccgccgc aactcgtcgt
    12961 gcaggcgcag ccgggtttcg tgcatctcgg ggaggtccgt ttcgatatag cggagggggt
    13021 gggtgcggct catggcgtcg ccacggaacg cgaagccgct ccccagctcc acgatctgct
    13081 tgatgccagc cgtcttgagg gccgtctcca ggcacttgta gcgggcctcg agcgtcgggg
    13141 ccatccagct cagcagctcg ggcgcggggg cgtctccgtc cagcatctcc cgcaccagtt
    13201 gcgcggaacc gatgcgcgtg gcgatttcct cggcgaaggg aatgtcggaa tggcgccgca
    13261 tctcggcgac cagcctggcc gtggggctga tgttgtcgta atcgcggagg ctcatctcgt
    13321 tttccttggt tgcgcctggt ttgccgtcgc ccgataagcc ggtcacggcc ggagtgcaag
    13381 catgtttgct tctccgcgac ctcacggaga gtgcgattgc ggcccatcgc gcgcgctgct
    13441 gtagtcacgc gcctcatgaa gaaaccctct ccctcctccg ggactccccg ggagctgagc
    13501 cgccgcacgt tcctgggtgg cgcggccgtc gccagcacgc tcgtggccct ggatgtccag
    13561 gcccagccct ccgcgaactc cacccctccc gccgctccgc gcggctcggc cttcgagctg
    13621 gaggaggcca cgctcgccgg gcttcaggcg gacctctcgt tggggaagta caccgcgcac
    13681 ggcctcacgg agcactacct cgcgcgcatc caggaaatcg acaagggagg caccgcgctc
    13741 gggtccgtca tcgagctcaa cccggacgcg ctcgccatcg cggcggcgct cgacgcggag
    13801 cgcgaggcga aggggccgcg gggcccgctg cacggcattc ccgtgctcat caaggacaac
    13861 atcgggacgg cggacaagat gcagaccacc gcgggctcgc tcgcgctcgt gggcgccgtg
    13921 ccctcgcggg atgcgttcgt ggtggagcgc ttgagggccg cgggcgcggt catcctcggc
    13981 aagacgaacc tcagcgagtg ggccaacttc cgttccacgc actcgtgcag cggttggagc
    14041 gggcggggag gccagtgccg caatccctac gcgctggacc gcacgccgtc gggctcgagc
    14101 tcgggctcgg gggcggccac ggcggcgaat ctgtgcgcgg tgtccgtggg cacggagacg
    14161 gatggctcca tcgtctcgcc ctcggcggca tgctcgctcg tggggctcaa gccgacggtg
    14221 gggctggtga gccgctcggg catcgtgccc ctgtcacaca cccaggacag cgcgggtccc
    14281 atgacgcgca cggtgacgga cgcggccgtg ctcctcgggg tgctcgcggg ggtggatccg
    14341 cgcgacgcgg tgacggccgc gagccagcgc catgcgcacg cggactacac gcgcttcctc
    14401 gacgtgaacg ggttgaaggg agcgcgcatc ggcgtgccgc gcgagcggtt cttcggctac
    14461 caccccgcca cggacgcgct catcgagcgg gcgttggacg tgctgaaggc gcggggcgcg
    14521 gagctcatcg aggcgcccat cccctcggcg gcgaagctgg acgagccgga gctggaggtg
    14581 ctgctccacg acttcaaggc ggacatcgag gcgtacctcg cggggctggg ggagcggacg
    14641 cggctgaaga cgctggcgga cctcatccgg ttcaacgagg agcaccggga cacggagctg
    14701 gcgtggtttg gccaggagct cttccatcag gcgcaggaga aggggccgct gacggacaag
    14761 aagtaccgca aggcgttgga ggcgtgccgg aagctgtcga gggagcaggg catcgacgcg
    14821 gtgatggcga agcacgagct ggacgcgctg gtggcgccga cgcaggcgcc tccggggctc
    14881 atcgacctgg tgaacggaga ccactggctg ggaagcagtt ccacgccagc ggcggtggcg
    14941 ggctacccga gcatcaccgt gcccgcgggt tacatcgccg gactgccggt gggcctgtcc
    15001 ttcatcggga aggcctggag cgagcccacg ctgttgcggc tcgccttcgc ctacgagcag
    15061 gccacgaagc accgccgccc gcccatgttc gccccgacgg cggacctgcg acccgccaag
    15121 gtgtagggag ggtctgtgcg cgggagctgt actggactcg acactcgaaa cggctgggat
    15181 gacgggggcg gggagggtga acgagtcagt ccgcgctatg aaggaacacc cgcgactgga
    15241 tgctcgcggg tcccgtcagc ctcaacccct cctcgaaccc cacctctgtc cttgagtcgc
    15301 gcgaggtggt ctactgacaa gcgccgtacg tgtgttggca accgccaatg ctttccgtca
    15361 cagaggtgac cgagcacccg gtgctgcact tcacgcaaat cgtctctgtg tggatgtagt
    15421 tgatgtcagg gcagtacatg gtgtcggtag tcctggtgta gccagtgcca cacggcgcct
    15481 gcgttgtcgt cctggtacat gccagcaacg ttcctggctg ggacgccata ccctccgact
    15541 gggtctccat ttcgtcacca ttcacgggaa gctcagtccc acagccgaag gcaaagagcg
    15601 agcccatcaa cccagtcatc acggcgaatc gcttcattcg aatcctcttg tccgtcttca
    15661 ccaccattgg tgcgtggata tcacgcacag tgcggctggc ggagtcaagg attcgaaacc
    15721 gcgacttgaa cgggaacgaa acctggcctg gacgggggag ccaaccgccg tccaagtctt
    15781 tccgatgact tgggggctgt ggtgccgggc ttgaatcttt caacttcttt gacacatgag
    15841 gggcacttcc tctgagcgct cctggccgcg cgggcttcgc tcgccggatg gcccacgcgc
    15901 ctcttctcta tttgaagaac accttgcggt gtttgtgccc gcctcggata tggttgggga
    15961 agtagttgac gccggccacc tccgtgccga acagatcctg cttgagcgct cggccagcga
    16021 tgcgatcgtc gtagatgaaa ttggtgcgat ccggcgcctc gtcggcggga aacagcactg
    16081 cggtaaaatc agcgtggccc acatcggtga cgtcgccgct gatgcaccag agcttgttct
    16141 gagacaagag ccagatgtag ttacggttcg cgaatccagc gaccgccgag ttgaactgct
    16201 gcgaggctct cccattcacg tcgcgaagcg ccgctctggg atcgaggttc gtcgggaact
    16261 ccttggcgtg aaagaagaga ccgacatcct gggtgcgcgc gacgcctcct cccgccacgt
    16321 ccacacggac caggtgggca tggaacaggt cctgatcatc cagtcggtgg ccgtcggtcg
    16381 cggcgatgag atcgaacagg ccgtagagaa acttgtggac gtgcttgtcg gacttccgtc
    16441 cgggagtggc ggcggccggg ttcaaggcgc cgctggcgtg gttccagatc tcgttggtca
    16501 gggccgtgag cttgggcacc agggattgca ggatgacgtt cgtcgcttgt tcggcactgc
    16561 cgggaagaaa gcgctgtgcc cgaaccagga gcgctggcaa ctggggacag gccgggagtt
    16621 cccgaatcca tgcgcgagcg gtcccctgaa cgagatcccg agccatgcgc gccgcggcgg
    16681 tcatgagttc agccccaggc tcatgaggag ggacatgccg gggaatggtt cgaacatggg
    16741 cttctccgag gattcggaag caggtggcga gaacggcttg gcttacagta ccacaggcaa
    16801 cctcgttccc gctcatggcc ggctcagtgt caaaggattc gaaactggga gttctttgac
    16861 accctcactg ccctcactgc ggcccacgaa gtacaattct ccggctatac tggagcaggt
    16921 cccgacgcga aaccaaagac gcgccgggcc tcccatgtgg ttgaaggtgg cttttcggag
    16981 actcgaatga ccatcaacgt caagaacagg ccggcgccga ggacgctcaa cacgacgtcc
    17041 acccaggcac ccgcgaagtc gacgccaacg gccaagagcg acgcggcgaa tgggaccgcg
    17101 ggcgcgagtc cgagcccgca ggtccagccg cagaagccgt ccgcatccgc cccgcccagc
    17161 tatcaccagg accagctcgg caaaccgaag gcgcctgccc aggcgccctc gggcaacgcg
    17221 gtgttccagt caaggcaaga catcgccacg ctcaactcgc ggcgaggctc cgtgttctcg
    17281 acccggcccg cacagggaac ttcggccagc tccgcccccc tcgccacgag cgccaggcaa
    17341 gcgcccgcga aattccagca gctcgcgacg acgcaccagg cggagatcac cgcatggtcc
    17401 gatcaggcca ataatccgac catccagaac tcctccgaga aggggggggt ctgtgccgcg
    17461 atggtcaatg agtgggctcg cgcgggctcg gcgggccccc agcaggaggc cgacttccgc
    17521 aagcgcctga acgatggcga cacccagcac ttcgtcgatc tgcagcgcac gagcaggcag
    17581 aagcatgagc agttcatcaa gaacgacgac ttcctcgaga gccaccccat tgcgaaccac
    17641 ctgaaatcag acgttcgcaa tgaactcaag gcggagaacg acaaacacaa tcagaccatg
    17701 aacgtcgctg gtttcaagcc ggaggacatg ctgttccccg ccaccaagcg catcaactcg
    17761 aatgagcacc tggccgagat ggtgtcaggc gcgatgcaga ccgccaagcc attggtcccc
    17821 gagggcacga gcttcttcgc caagatgatg gtcacggaca agaatcaaac ggggggtcac
    17881 gccatcggcg tcaagatgac tcatctgccc ggtggaaaga tggagtactc gatgctggat
    17941 cccaacacgg gcgagttctc gaagatcccc gagcagaatc tcaagaactt catgaccgac
    18001 cacatgaaca agacgtatgg gaaggactat gtgggaggcg gtctctcact gcatgcgatg
    18061 atgccgggct gaggcctggg ggcttgcccc ggtgacgggg cattcccgcg tttcatccgg
    18121 agcggtcccc gggcaaggtc gagccaccgc acgttgactg gaagcgccgc ggttcgagaa
    18181 gaccgaggcg tttcgctttc gtacgctcag gtcggctaaa tactacgcgt gggctgcagg
    18241 accgcctccg agagcgccga catgcgtacg ggatcggcga ccgcgtactc cggatcggcg
    18301 atcatgttcg cgaaggcgcg ccggctcgga tagcggacca gggcgacggt gtcccaggcc
    18361 tggcccggct ccgccgcgag cggcgtcatg ccgtcgcccg cgtagaggat ctccgcgccg
    18421 tagcgcgcga cgagcggacc cgccatctgc aggtatttga gatagcgctc ccgtccgccg
    18481 tcggggcgga agcggagcag gttgagcatg acgaccggcg cgccgtcgtc ctcgcggagg
    18541 aagcgatcga gatcggcggg attgaacgca atcatttgga ttcctttcgt tacttgagag
    18601 tctgctgcgg cacgttactg aagaggagga tgctcttgat gcgatgctcg ccgtcgaagg
    18661 cgacgacgtc gtagcccgtg aagccagcgt tccccgcggc gtcgacgaac tgccaggtgg
    18721 cgatggcgtt gtcttcccag ccgagcatcg caacgaggcg gaaggagcca cccgggctcc
    18781 gcgtctggaa ggccctgagg tggtctgcca ggtcgtcgat gccggtccgc ggtttcgtgg
    18841 ggttcgtgaa gacgatcccc tccgtgacgc tcgcatgcag cagctgcagc cgtcggtcgt
    18901 ccgggatcgc cgaccacgcg gagaggaact tctcgtacgc ggccacgcgg aagtccgtca
    18961 tcgcgacctg ctccgtcatc gaggtgcgca ccgcgggcgt cggcggtgcg gtcgtggcgc
    19021 agcccgtcgc gaggcagagc ccgaccgaga cgaggagcgc ccgcgccctt gcggtgccca
    19081 gcgctcgggc tgtacaccgc ggtccatgag cgccatcgac ttcgaggtct ccgttccgca
    19141 gctgcgatgc ttcatcgccg tggtggacgc cggctcggtc gccgaggctg gtcgccgcct
    19201 cgggatgtcg gcggcgagcg tgtcgaaggc gatcacccgg ctggaggagg gcgccggcgt
    19261 gcggctcctc caccggtcga cccacgcgct ttctctcacc gaggccggag aggcgctgct
    19321 cgagccggcg cgcgaggccg tgcgcgcggc ggaggccttc gaggatgcgg ccgggcatgc
    19381 cagaggcagc ggcgacgccg gcgtcgtgcg cctcactgcg gcggtggggt tcgtccggca
    19441 cgtcctcgtg ccgatgcttg gcgagctcgc gcggcttcat cccgagatcc agctcgacgt
    19501 ccgcgcgacg aacgaggtcc tcgatcttgc cgacgacggc atcgacctcg cgatccgatc
    19561 tggctccctc gtcggtctgc caggccacat ccatcaaacc tggttcacgt gcccgtgggt
    19621 gatctgcgcc gcgccgagct acctcgcccg gcgacccgcg ccgcggacga tctcggagct
    19681 cgacgagcac gacctcatca ggttccggaa cccccagagc ggacagatcc agccctggcc
    19741 ccaccggacg gtggccggca cgaccggggg gacctacgag ccacgggcgc ggttcgcgtt
    19801 cgacgacggc ggcgccgtct ggggtacgat gctcgcgggc ggcggcatcg catgcgtccc
    19861 gctctacatc gcggccgcct cgctccggaa cggcgcggca gtcgagctcc tcgccgattt
    19921 ccgcggcgcc gccgcgactg tggtcatgct gcgccgggat cgccggctga cgcccggtcg
    19981 cctctctacg ctgatggcct tcctgagcgc gcgtgccccg gacttctctg atctcctctg
    20041 acccgcatcg tcttgacatg ccgacgactc tggcagcgtg cgcgcggtcg ctgtagccct
    20101 cgggcgggca gggcagtgtt gccctcgcgg caggaccgtc acggcttcca gacgaggagc
    20161 gtgggaccgc gcggggcgaa atcgttgttc gtggtctcgc gcgtgtgctg gatctcgagg
    20221 gggctaccgg ttcgccagcc tcgtggcggg gccgtgaggg gcgcgacctg gtcggtcttg
    20281 gcaggactgt aaaggtggcg acccgcggag gttctgtcga gacttggcta cccaacgttg
    20341 gggtcctgcc ccgacacccc gcgccgactg tccggcgcgt cagaggcctc tatcgccgtt
    20401 cacgtcgtcg ttctcgtgct gacgagtcgt ctgacacctg gggcgacacc tggggctggg
    20461 gcggcccctg acgagtcgtc tgatacctgc ggcaccctcc cacgaccgca ttcacttccg
    20521 cgcgcctacg agtcgtctga cacccttcct gggacaccct tcctggctcc aatccaccaa
    20581 ctttccgagt tttttggaca ggttggcgcg caggtactgc atgaaggagg cgtgctcagc
    20641 ctccgcgccc acaccagcag gtgaattagt tctccgaaat cttcgagccc ttgatgatca
    20701 cgtctccgct ggcggtaatt tcaatcttcg cgcccttgat gaccacgtca ccattcttct
    20761 tcacctgcag ggtggcggag ccgaccttga gggtgaactg ttcctgggcg accagcgaca
    20821 gctccttggc ggatagcgtg taggagtcct tgacggcgtg gttgagtttg ccgcctacgc
    20881 tcagcagcag gtcctttccc accttgaggg tgcgggattt gtcgacctgc tcggacatgt
    20941 ctcctcctac ttggagggtc cgcgagccct tgaccgtctc ggacttcttc gcgcccacca
    21001 cctctacctt ggcaccgccc acctgctcgg acttgaggcc gcccacgagt tggttgagtg
    21061 ctcca
//
