LOCUS       NZ_CP022098            21059 bp    DNA     circular CON 17-FEB-2024
DEFINITION  Cystobacter fuscus strain DSM 52655 chromosome, complete genome.
ACCESSION   NZ_CP022098
VERSION     NZ_CP022098.1
KEYWORDS    RefSeq.
SOURCE      Cystobacter fuscus
  ORGANISM  Cystobacter fuscus
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Cystobacter.
REFERENCE   1  (bases 1 to 12349744)
  AUTHORS   Rupp,O., Goesmann,A. and Sogaard-Andersen,L.
  TITLE     Sequencing and comparative analysis of myxobacterial genomes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12349744)
  AUTHORS   Bruckskotten,M., Treuner-Lange,A., Rupp,O., Goesmann,A. and
            Sogaard-Andersen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2017) Department of Ecophysiology, Max Planck
            Institute for Terrestrial Microbiology, Karl von Frisch Str. 10,
            Marburg, Hessen 35043, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 09-AUG-2016
            Assembly Method                   :: Celera Assembler v. 8.1
            Expected Final Version            :: yes
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/17/2024 10:04:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,093
            CDSs (total)                      :: 10,016
            Genes (coding)                    :: 9,906
            CDSs (with protein)               :: 9,906
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 26 of 110
            Pseudo Genes (incomplete)         :: 101 of 110
            Pseudo Genes (internal stop)      :: 1 of 110
            Pseudo Genes (multiple problems)  :: 17 of 110
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:24:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3474638
            Orig. end                         :: 3495697
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21059
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="17"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21059
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21059
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11059](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11059
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    212..225
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.0"
                     /tool="antismash"
     gene            426..1160
                     /gene="tsaB"
                     /locus_tag="CYFUS_RS14385"
                     /old_locus_tag="CYFUS_002840"
     CDS             426..1160
                     /EC_number="2.3.1.234"
                     /GO_function="GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="tsaB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013939133.1"
                     /locus_tag="CYFUS_RS14385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_002840"
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="WP_095985744.1"
                     /transl_table=11
                     /translation="MFLALDSSTLTLSLALVEREGEALRVLEHLVVAPPRKQSEALPGV
                     VGEVLARHGVTLGALEGLVIGLGPGSFTGLRIGLSCVKGLAYAARLKVAGASSLAAVAL
                     EGPEGPPLFALAVARKDDLYLGPYRRTGLGVEALGPEEAMSPEEVAQRMAAEPEALALG
                     PALPEYRAALERLGVAPSRLLDAPTFPSAVALAHLARLPEAQSLEALFALEPHYVRASA
                     PELNPKFPPLPGPAPTARLKED"
     gene            complement(1174..1392)
                     /locus_tag="CYFUS_RS14390"
                     /old_locus_tag="CYFUS_002841"
     CDS             complement(1174..1392)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS14390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_002841"
                     /product="hypothetical protein"
                     /protein_id="WP_095985745.1"
                     /transl_table=11
                     /translation="MYAEPRGGFESITYVTFDGRVRLSRHLALGLELPLSLRAYDFGPD
                     ATQAIGGGGARITLSFMPDDAFGVAGP"
     gene            1560..2588
                     /locus_tag="CYFUS_RS14395"
                     /old_locus_tag="CYFUS_002842"
     CDS             1560..2588
                     /EC_number="1.2.1.11"
                     /GO_function="GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1219: N-acetyl-gamma-glutamyl-phosphate reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011552630.1"
                     /locus_tag="CYFUS_RS14395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_002842"
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="WP_095985746.1"
                     /transl_table=11
                     /translation="MNENLRIAVVGATGVVGREVVSTLFDREVSAEQLTLLASERSAGE
                     ELDYGEETLEVEKVSAESFRGMGLVLLATPAEASRSLAHQAQAAGAWVVDVSSAFRADG
                     AVPLVLPGFNSELLEANFKGRLVALPSAVTTALACILEPLRQAFGVAQVQVTAMMGASS
                     AGNAGVRELEQQTAALLSGRDPEAHTFPQRVGFNLVPQVRPFLANSPWTEEEAGWTLEC
                     ARLFAPRGEVPVVAGTAVQVPTFHGHGLSLQVRLKKPAPVEQARAALKGSPALKVLDSP
                     GEKIYPMPSLVTADPTVHVGRLRSFPQAPEWLTLFATVDNAGRGAALNLVEAGLRLATR
                     PS"
     gene            2717..3604
                     /locus_tag="CYFUS_RS14400"
                     /old_locus_tag="CYFUS_002843"
     CDS             2717..3604
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_157758447.1"
                     /locus_tag="CYFUS_RS14400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_002843"
                     /product="MXAN_2561 family MXYO-CTERM-anchored protein"
                     /protein_id="WP_157758447.1"
                     /transl_table=11
                     /translation="MRTFLLTTALLLSSAASAQVKFTFGTANNETLSFGKADCSNPVTV
                     TWTRTIQPCDRLTLWITTTGSCQGAAADTSKGDVALDEISLSTFQAATQGTFNLDRSRL
                     PFVTSDGGAACGSLNEEKTFSLCGATKQTDNFYGCNSTVVNATAARITYDGKPPSAPTL
                     SATSGMDGAASITVNAPSDATRGVVRILLNGEEFRKVEWSLGKGALLVENLENDVTYEA
                     DATVFDAAGNESERSSPVQVIPTKTYGFMEHYGDSGGQEVGCGAVGGGVAGGAMLAVLG
                     FWLFSRRNRSWLEQ"
     gene            3589..4344
                     /locus_tag="CYFUS_RS14405"
                     /old_locus_tag="CYFUS_002844"
     CDS             3589..4344
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020477636.1"
                     /locus_tag="CYFUS_RS14405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_002844"
                     /product="MXAN_2562 family outer membrane beta-barrel
                     protein"
                     /protein_id="WP_095985748.1"
                     /transl_table=11
                     /translation="MARAVAFGVAVLLAALPGQAQVYSDAPTQSPRGGSVELRLGSYRP
                     QIDGEEGVSGGPFTDIYGEGRWWLFELELQRFFYQGIGTAGLSLSVGYAEKFGYALTKD
                     KQTPSSERTSFHVVPLHLRGVYRFDYPAFQWGFPLIPYVKPGLVFVPWWATKGGKLDEA
                     PATEGSEGSEGTPARKGRGVRFGWEVAVGLSFMLDVLEPRFARDFDSDLGINHSYIFAE
                     YTYSKVNSFGQPGLNLSDSYWMFGLALDY"
     gene            4352..6184
                     /locus_tag="CYFUS_RS14410"
                     /old_locus_tag="CYFUS_002845"
     CDS             4352..6184
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040138.3"
                     /locus_tag="CYFUS_RS14410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_002845"
                     /product="PKD domain-containing protein"
                     /protein_id="WP_095985749.1"
                     /transl_table=11
                     /translation="MTLPPCSSVRALMAVLVVAVALSGPGCRRVVKPEAGGDRTVEAGV
                     PVDFGAGGQDAPVVSWDFGDGSPVQSGTRVVHAFERPGTYAVRALDRDAVLASATLTVV
                     PRPVLRAIPDDAEVAIFFPQLRGNVDPLMGFMSQLVGESQVLQTLDSVPLLALVLRDVT
                     GGQARIVDPDEGLGFFSLPRFEGSVVLLGVTDTQAAVDAVVKEVQSRGARVMRREPQGT
                     VFLRRDNGMSMVVFPDRGYLYVVVPDAPESESEQEEGTPQQVLAEVGDDGLAAVEEVRA
                     HIQGASGSGLSEQPLLTSLRAKVGAGHVHVFARPEGNDASASIQGLWAALTFQDTRADL
                     EGWVVSDKSLFQGGTAPGSELLARAPLGPIAALTVSLPPETLAKLVFGAPGSERRAQTE
                     QRMARQGLDAAGVQGMLGALRGDLSLLAYLDAPAFYRNLLKGARGPEPRGSVLFQAGLV
                     RSEPVLEWLTGVLESRGQPFEVLKEKGATRLRTRVFEQPVDVTLTADRLTLRGGESLEA
                     RAQGGVGEELRQRFGAQGFEPGHLSAMVDMGRVRSELDSPREVPGVPPQQLPVARALVG
                     TLIDQLPPIESLFLDFAPEQGGGRFRMSTVLRSR"
     gene            6195..6860
                     /gene="moaD"
                     /locus_tag="CYFUS_RS53910"
                     /old_locus_tag="CYFUS_002846"
     CDS             6195..6860
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="moaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002613493.1"
                     /locus_tag="CYFUS_RS53910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_002846"
                     /product="molybdopterin converting factor subunit 1"
                     /protein_id="WP_095985750.1"
                     /transl_table=11
                     /translation="MSSLTILYFAAARERAGLARESLEVPAGTRVGEVLSLLASRHPGL
                     APLLPHLRVAVNQEFSTSETEVPPGAEVALIPPVAGGSGGLFRVVDRPLRLEEVVEAVA
                     SEALGGLVTFSGAVRNQTKGRRVVRLEYEAYPPMAEKKLAEIGAEVAERFNGTRLAIVH
                     RVGTLHPGELAVVIAAAAPHRKEAFLGCEHAIERLKQDVPIWKKEFFEDGEVWVGLGP"
     gene            6927..8054
                     /locus_tag="CYFUS_RS14420"
                     /old_locus_tag="CYFUS_002847"
     CDS             6927..8054
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024700.4"
                     /locus_tag="CYFUS_RS14420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_002847"
                     /product="ATP-binding protein"
                     /protein_id="WP_095985751.1"
                     /transl_table=11
                     /translation="MGFELEVDNYRALRKIRWKAEGVCALVGPNGSGKTTLLSVLQFLR
                     HAWIQDFGRALNAHGGALLFRHRQASIHEPVRFALAVGSARWEAEPSTSLLGVVFPVPE
                     RLIVDKKVVAEQRAGESGFRVLEENKNADGQSFLASVAVASPELRSAMEPLAVALSASV
                     LYSFDAFWQLKREGSREGTDVWLSQDGRNAFTVMRNWIAGNRAYRPRWEWVRSGLRECF
                     PDLFDDLDFAVAGQTVAAQFYGPGGGDPTPMHLAPNGLLMALLILCAVASADHGMVCID
                     EPENGLHPYAIQRLISLMRERAEARGLTIVLATHSPTLLNEFNDQLDHVFIMESGHESL
                     PVRLDQHQNPEWLRNFALGDLYMNQTIAPQVQPKT"
     gene            8051..8938
                     /locus_tag="CYFUS_RS14425"
                     /old_locus_tag="CYFUS_002848"
     CDS             8051..8938
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS14425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_002848"
                     /product="hypothetical protein"
                     /protein_id="WP_095985752.1"
                     /transl_table=11
                     /translation="MSRVQLVVTGEMERVALAASLRHSFPAHELDFLPTQKVQDFTSSR
                     LGNHPGRVPGLKTRAQEMAQAIVSAFSPGRFLNAIPDLVLAVDDLELVNVDQPHIVTTY
                     LARELELTLKDRKFLPADETRVRELLRRRASFHLFVPMPEAYFYAESAALTRAGAKAAS
                     RFDVAQHDTEAFEVDDPAYRQWLEKRAPNAVEPHRHPKQYLRYLCDPSASAERAYRETK
                     EGALALEKLAWSEVTARRARETYARALLEDFADGIGANWQSPGSVAPLTARRSGGLLRN
                     LAPAVPPTAAVLGQ"
     gene            complement(8975..9622)
                     /locus_tag="CYFUS_RS14430"
                     /old_locus_tag="CYFUS_002849"
     CDS             complement(8975..9622)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624613.1"
                     /locus_tag="CYFUS_RS14430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_002849"
                     /product="hypothetical protein"
                     /protein_id="WP_232537554.1"
                     /transl_table=11
                     /translation="MKTKASHDGLFCELYWGTTRNEAWNFGPEQTRVLAAPDETVPLPL
                     YGFTLPEEPFLIAERTPEGYRVFVPPASRVERSRRGEAFQPVPDTELRRSGASAWVELT
                     AEDRVRLSQGDLSLLLAPSVAGKRASGLGARDLGLLAMLLALLLSIPVGLILAGHSPEH
                     MAESNARALAAAREKEQAERKRLGVDTPARPLAPETLPDAGVRTLPGSFGIH"
     gene            10001..11059
                     /locus_tag="CYFUS_RS14435"
                     /old_locus_tag="CYFUS_002850"
     CDS             10001..11059
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="CYFUS_RS14435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_002850"
                     /product="terpene synthase family protein"
                     /protein_id="WP_095985754.1"
                     /sec_met_domain="T1TS (E-value: 3.5e-16, bitscore: 58.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAASAAFHFNDKQMVARVPPDLGTVRREPRYARVDALIQTLVGRD
                     EAVFDIQVDGTRHRIAWPIDFSEFRIIASTYPVSLDLSRRGHFPELEKLRAHMLQGDFD
                     LLTYYTCSTVSPLYLQNSQDRMDWFFALDYFVDGPLVPPELREAVVRDLSAWLEDRRHV
                     SRLPWVNMISALLRIVLEDIEREGLDTSRIVREIRGYYEGFLLEFDKQVPLPRYLENRG
                     MSIGMRPELEFCFAYQGRPLPARDRDAAERMKHAAADLVALQNDVLSLRKEEEQEQEHL
                     RLKSYFPISHEYVSFANDFYAARFGEFLAMRPRAPGPLEALWKMCGQWISGSLLWHLTS
                     RRYDLGQFQVLA"
     gene            complement(11051..12715)
                     /locus_tag="CYFUS_RS14440"
                     /old_locus_tag="CYFUS_002851"
     CDS             complement(11051..12715)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015345933.1"
                     /locus_tag="CYFUS_RS14440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_002851"
                     /product="ATP-binding protein"
                     /protein_id="WP_095985755.1"
                     /transl_table=11
                     /translation="MRALKQGSDDAQLTLGRATLLRALMELEQGNPEGCMALCAVRDET
                     QAIVDFELIFSNDADVMKRVCPGLVVGHRLSEAASEALRSQFALLSQVVETRRAARSEL
                     READCWLRGTVTPLLDGVLVRLQDVTALVRDVREHEARLEREQSGRREAEALAREQSRQ
                     LLAAQEKLVRSGGLMAAGQLAAGVGHEINNPLAFVTGNLHVALEQLGTLARELPPAAER
                     LRETTRALDDARKGAERIRAIVKELRTLARASDTPPESVDVGAALELSLSMAMPHIRHR
                     ARVVRHVVPVPRVPGNESKLGQVILNLLINAAQAIPEGDAIRHAITVVTRMEGAQVVLE
                     VRDTGKGMSAEVLARIFEPFFTTKLPGEGTGLGLPISLDIIRGMGGEMKVQSEPGRGSS
                     FQLVLPVIHEATDPKPAPPVVKHPAPPRRRVLIVDDEPAIGTMMVRVLGRHHEVKVVHS
                     GREALELLCGEPDYDRVFCDLMMGDMTGMDLHAALARRRPEYLPRVIFMTGGAFTDRAR
                     AFLAEASVERLDKPFEAGSLRERVERPLPGERERHSR"
     misc_feature    12811..12820
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.04"
                     /tool="antismash"
     misc_feature    12813..12826
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.17"
                     /tool="antismash"
     misc_feature    12813..12827
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.35"
                     /tool="antismash"
     gene            complement(12895..14121)
                     /locus_tag="CYFUS_RS14445"
                     /old_locus_tag="CYFUS_002852"
     CDS             complement(12895..14121)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M50"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624616.1"
                     /locus_tag="CYFUS_RS14445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_002852"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_095985756.1"
                     /sec_met_domain="Peptidase_M50 (E-value: 2.6e-57, bitscore:
                     193.1, seeds: 56, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHYLPLLLALGLLVALHELGHLVAARLLGLRVERYTLGFGPPVLS
                     WRWRGTDYALGAVPLGGSVRIHGMNPHAPGLEPTDSTSFPAQRPWKRLLVLLGGPLANA
                     LFALGVLFALYTTGTHVVVPLTVGTITPGSEAARAQLLPGDRLVSVDGEPLESWSGFVE
                     LIARRPGRELRLGVERQGEEREVVVRPRLDERGVGRIGVSQQYVYRAHAPGQALLQALA
                     HTGNLVLEGARMVERLLRGTQGIALANPLGVVKQSSGAAGSGLGAFLRVMVNLSMALAF
                     FHLLPLPSLDGGRIVFVLIESISGRKVPARVETLVHAVGFVALLGVVLTVSLADLRQRM
                     GRAQQGLDAREPGDSPLFLWEKNAGGTRPGTPSHVDDCPAPPPTPSGTTAASTPTNACT
                     KTEAASAPR"
     gene            complement(14131..14553)
                     /locus_tag="CYFUS_RS14450"
                     /old_locus_tag="CYFUS_002853"
     CDS             complement(14131..14553)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002639070.1"
                     /locus_tag="CYFUS_RS14450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_002853"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_095985757.1"
                     /transl_table=11
                     /translation="MASYKNPVPTVDCIIELAGERVVLIRRKNPPLGWALPGGFVDEGE
                     RLDVAAVREVKEETGLDVELVEQFFTYSDPSRDPRRHTLSTVFIGRARGEPRGADDAAE
                     AKAFPVDALPRELCFDHGTILADYLTYKRTGQRRKL"
     gene            14552..15121
                     /locus_tag="CYFUS_RS14455"
                     /old_locus_tag="CYFUS_002854"
     CDS             14552..15121
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS14455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_002854"
                     /product="hypothetical protein"
                     /protein_id="WP_157758448.1"
                     /transl_table=11
                     /translation="MGRHSNPWPPHCTAHVGSRCVSLLAVASLPLLRWFLPCTLALGLG
                     GGCTRANLQNEDRYEFTTTELIRDDCGLLSSEESLWDGELKIDGDVVRMTSDWRGLQLI
                     GFVLPRGEFNDDAFVLDGSESSAAITLRGKQCLVEQVWMHLEGTTQCATRFDGVLSVRI
                     EPRVEQPECACQLWVKYRAIQGSGCQ"
     gene            15197..17164
                     /gene="acs"
                     /locus_tag="CYFUS_RS14460"
                     /old_locus_tag="CYFUS_002855"
     CDS             15197..17164
                     /EC_number="6.2.1.1"
                     /GO_function="GO:0003987 - acetate-CoA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019427 - acetyl-CoA biosynthetic process
                     from acetate [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (100-532). E-value:
                     2.2e-102. Score: 334.7. Matches aSDomain:
                     nrpspksdomains_CYFUS_RS14460_AMP-binding.1"
                     /codon_start=1
                     /gene="acs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624619.1"
                     /locus_tag="CYFUS_RS14460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_002855"
                     /product="acetate--CoA ligase"
                     /protein_id="WP_095985759.1"
                     /sec_met_domain="AMP-binding (E-value: 3.4e-111, bitscore:
                     371.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAETPRPNPQALESVLVENRLFPPPEDFSRRAHIGSMEDYRRLWD
                     EAEKNPEAYWGARAREELYWKEPFQTVLDWKPPHARWFVEGRTNLAYNCLDRHLPALKD
                     KTAILFEGEPGDRRKVTYGELSRQVNQLANGLRALGVKKGDRVGIYLPMVPEAAVAMLA
                     CARVGAVHSVVFGGFSAEALLERMNDAGARVLLTADGGWRKGAVVPLLDNVRKALPQMK
                     NLEHVVVLQRTTQGALRLEGKEQSWSELTQKQSDVCEPEWVESEHPLFILYTSGSTGKP
                     KGVLHTTGGYAVFASLSSRWVFDLKKEDVYWCTADIGWVTGHSYVVYGPLMNGVTSVIY
                     EGALTHPGADRTWELIAREKISILYTAPTAIRAFMRLGDDIPRKHDMSSLRLLGSVGEP
                     INPEAWMWYRDVIGGGRCPVVDTWWQTETGGIMLSPLPGATPTKPGSATLPLPGIHTEV
                     LDKQGKPVGANQGGQLFITRPWPSMLRTVYGDPQRYVNTYFSELPGVYFTGDGARRDDD
                     GYFWLMGRVDDVVNVAGHRLGTAEVESALVAHKSVAEAAVVGRPDDLKGTALVAFITLK
                     KGVGHSPELKKELASHVGKEIGAIARPDEIRFAEGLPKTRSGKIMRRLLRDVASGKQTT
                     GDTTTLEDLNVLATLRSDEE"
     aSDomain        15497..16792
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CYFUS_RS14460_AMP-binding.1"
                     /evalue="2.20E-102"
                     /label="CYFUS_RS14460_AMP-binding.1"
                     /locus_tag="CYFUS_RS14460"
                     /protein_end="532"
                     /protein_start="100"
                     /score="334.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ALKDKTAILFEGEPGDRRKVTYGELSRQVNQLANGLRALGVKKGD
                     RVGIYLPMVPEAAVAMLACARVGAVHSVVFGGFSAEALLERMNDAGARVLLTADGGWRK
                     GAVVPLLDNVRKALPQMKNLEHVVVLQRTTQGALRLEGKEQSWSELTQKQSDVCEPEWV
                     ESEHPLFILYTSGSTGKPKGVLHTTGGYAVFASLSSRWVFDLKKEDVYWCTADIGWVTG
                     HSYVVYGPLMNGVTSVIYEGALTHPGADRTWELIAREKISILYTAPTAIRAFMRLGDDI
                     PRKHDMSSLRLLGSVGEPINPEAWMWYRDVIGGGRCPVVDTWWQTETGGIMLSPLPGAT
                     PTKPGSATLPLPGIHTEVLDKQGKPVGANQGGQLFITRPWPSMLRTVYGDPQRYVNTYF
                     SELPGVYFTGDGARRDDDGYFWLMGRVDDVVNV"
     CDS_motif       16004..16057
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CYFUS_RS14460_0001"
                     /evalue="8.50E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="CYFUS_RS14460"
                     /protein_end="287"
                     /protein_start="269"
                     /score="24.5"
                     /tool="antismash"
                     /translation="FILYTSGSTGKPKGVLHT"
     CDS_motif       16763..16825
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CYFUS_RS14460_0002"
                     /evalue="1.30E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="CYFUS_RS14460"
                     /protein_end="543"
                     /protein_start="522"
                     /score="14.7"
                     /tool="antismash"
                     /translation="MGRVDDVVNVAGHRLGTAEVE"
     gene            17249..17746
                     /locus_tag="CYFUS_RS14465"
                     /old_locus_tag="CYFUS_002856"
     CDS             17249..17746
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002624621.1"
                     /locus_tag="CYFUS_RS14465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_002856"
                     /product="CinA family protein"
                     /protein_id="WP_095985760.1"
                     /transl_table=11
                     /translation="MMSESPDVLAVEVSRRCREKGVRLVLVEACTGGLVCARLTEVPGA
                     SSVVERGFIPYSNEAKVEQLGVPLELLQAHGSVSAEAVEALAHAALERSRADWAVAETG
                     IAGPTGGTPHKPVGLAFLAVMRRGGRAEVERHVFTGDRSEVRRAISNRVMALLLARLES
                     ES"
     gene            18470..18865
                     /locus_tag="CYFUS_RS14475"
     CDS             18470..18865
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002621344.1"
                     /locus_tag="CYFUS_RS14475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_095985761.1"
                     /transl_table=11
                     /translation="MPYIPDFDTEAVLHILNSIIQKHPEGSPERDAIELAQIALIYPRH
                     IRKEDDFRRFYRDVYDPSFKLKVSHEFSTREEADEWLASGKAEDAERVRIAGKGFMVVR
                     LPGRSTFMSAPLEGEEEETDESGEGSE"
     misc_feature    18994..19007
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.6"
                     /tool="antismash"
     misc_feature    19217..19229
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     misc_feature    complement(19588..19602)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.97"
                     /tool="antismash"
     misc_feature    complement(19847..19861)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(20215..20228)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    complement(20363..20378)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.12"
                     /tool="antismash"
ORIGIN
        1 ggttgtgccg cgcgtgccac ccggggcgac gaggacacgg cggagcgcgc ttccgccacg
       61 cggggctacc tggaggaggg actcgcctcc tactacgccg atcgctacaa cggccgggcc
      121 accgccagcg gcgagaagct ggatccgaag aagtacaccg ccgcccaccc gaagctgccc
      181 ttcggcacgt gcctgcgggt ggtgaacatg gagaacaacc gctcggtgga ggtgcgcgtc
      241 aacgatcggg gcccctacgt gaagggccgg gtggtggacg tgtcgcacgt cgcggcgaag
      301 aagctggagc tcctggacaa ggggctcgcc cgggtgcggc tctaccgctg cgcgacccgc
      361 acctcgcagc tcgacgtgca gctcgacgtg cccaacgagt cgcgggcggg gtagaagccc
      421 tccccatgtt cctcgcgctc gactcttcca ccctcacgtt gtccctggcc ctggtggagc
      481 gggagggcga ggcgcttcgc gtcctcgaac acctggtggt ggcgccgccg cgcaagcaga
      541 gcgaggcgct ccccggtgtc gtgggggaag tgctcgcccg tcatggggtg acgctcggcg
      601 cgctggaggg gctggtgatt ggcctcgggc cgggctcctt cacggggctg cgcattggcc
      661 tgtcgtgcgt gaaggggctc gcgtacgcgg cgcggctcaa ggtggccggg gcctcgtcgc
      721 tggcggccgt ggcgctggag gggcccgagg ggccgccgct cttcgccctc gcggtggcgc
      781 gcaaggacga cctctacctg gggccctacc ggcgcacggg cctgggcgtg gaggccctgg
      841 gccccgagga ggccatgagt cccgaggagg tcgcccagcg catggccgcc gagcccgagg
      901 cgctcgccct gggacccgcg ctgcccgagt accgcgcggc cctggagcgc ctgggcgtgg
      961 ccccgtcgcg gctgctcgat gcgcccacgt tcccctcggc ggtggcgctc gcgcacctgg
     1021 cgcggctgcc cgaggcgcag tcgctggagg cgctcttcgc gctggagccg cactacgtcc
     1081 gtgcctccgc gcccgagctc aaccccaagt tccctccgct gcccggaccc gcgcccaccg
     1141 cgcgcctcaa ggaagactga ctcggcgacg gactcagggg ccggcgacgc cgaaggcatc
     1201 gtcgggcatg aagctcaggg tgatgcgcgc gccgcctccg ccgatggctt gcgtggcgtc
     1261 cggcccgaag tcgtaggcgc gcagggacag gggcagctcc agccccagcg ccagatgccg
     1321 ggacagccgg acgcgcccgt cgaaggtgac gtaggtgatg gactcgaagc cgccccgggg
     1381 ctcggcgtac acgccaggcc cccgtactgc ccgcccagga gcagtccccg gacgtcccct
     1441 ccatgagtcg acgtttgccg gaagccctcg gcgcccgcgg ggagagcggg gtgacatccg
     1501 gtggggggga ggcgagaagc gggacccacc gggccggggc ttggggtaaa gggggcgcca
     1561 tgaacgagaa cctgcgaatc gccgtggtgg gcgccacggg cgtggtgggc cgggaggtgg
     1621 tctccacgct cttcgaccgg gaggtatccg ccgagcagct caccctgctg gcctcggagc
     1681 gctccgcggg cgaggagctg gactacggcg aggagacgct cgaggtggag aaggtctcgg
     1741 ccgagtcctt ccggggaatg gggctggtgc tcctggccac tccggcggag gcctcgcgct
     1801 cgctcgcgca ccaggcgcag gcggcggggg cgtgggtggt ggacgtgagc tccgccttcc
     1861 gggccgacgg cgccgtgccg ctggtgctcc ccggcttcaa ctccgagctg ctggaggcga
     1921 acttcaaggg tcgcctggtg gcgttgccct cggcggtgac gaccgcgctg gcgtgcatcc
     1981 tcgagccgct gcgtcaggcg ttcggcgtgg cccaggtgca ggtgacggcg atgatggggg
     2041 cgtcctcggc gggcaacgcg ggcgtgcgcg agctggagca gcagacggcg gcgctcctgt
     2101 ccgggcgaga ccccgaggcg cacaccttcc cccagcgcgt gggcttcaac ctggtgcccc
     2161 aggtgcgccc cttcctcgcc aactcgccgt ggacggagga ggaggcgggc tggacgctgg
     2221 agtgcgcgcg cctcttcgcg ccccggggcg aggtgcccgt ggtggccggc accgccgtgc
     2281 aggtgcccac cttccacggc catggcctca gcctccaggt gcgcttgaag aagcccgcgc
     2341 cggtggagca ggcccgcgcc gcgctcaagg gctcgcccgc cctcaaggtg ctcgactccc
     2401 ccggggagaa gatctacccc atgcccagcc tcgtcaccgc ggaccccacc gtccatgtgg
     2461 gccgcctgcg ctccttcccc caggcccccg agtggctcac cctcttcgcc accgtggaca
     2521 acgccggccg gggcgccgcc ctcaacctcg tggaggccgg tctgcggctc gccacgcgcc
     2581 cctcctgaca atttggcaat gtcctttcgg ccctccctgc ccatttgacg gcgggtgggg
     2641 gggcccgctc cgggcgccgg agggggcggg ggccggattc ctcctggccc ctggcttgct
     2701 agcctccttc gcacccatgc gtaccttcct cctcacgacc gcgttgcttc tgtcctccgc
     2761 ggcttcggct caggtgaagt tcacgttcgg caccgccaac aacgagacgt tgagctttgg
     2821 caaggccgac tgctcgaatc ccgtgaccgt cacctggacg cggaccatcc agccctgcga
     2881 caggctcacc ctgtggatca ccacgacggg ctcgtgccag ggcgcagcgg ccgacacctc
     2941 gaagggagat gtcgcgctgg acgagatctc cctgtcgacc tttcaggccg cgacccaggg
     3001 caccttcaat ctcgatcgct cgcggctgcc cttcgtcacg tcggatggcg gggcggcatg
     3061 tggcagcctc aatgaggaga agacgttctc gctgtgcgga gccaccaaac agaccgacaa
     3121 cttctatggc tgcaactcca cggtggtgaa cgccacggcg gcccggatca cctacgatgg
     3181 caagccgccc tccgcgccca cgctctccgc gacgagcggc atggacggcg ccgcgagcat
     3241 caccgtgaat gccccgtcgg atgccacgcg cggggtggtg aggatcctgc tcaacggaga
     3301 ggagttccgg aaggtcgagt ggtcgctggg aaagggggcc ctcctggtgg agaacctgga
     3361 gaatgacgtc acctacgagg ccgacgccac cgtcttcgac gccgcgggca acgagagcga
     3421 gcggagctcg cccgtgcagg tcatccccac caagacgtat ggcttcatgg agcactacgg
     3481 cgattcgggt gggcaggagg tgggctgtgg ggcggtgggg ggtggggtcg cgggtggcgc
     3541 gatgctggcc gttctgggtt tctggttgtt ctcaaggaga aatcgttcat ggctcgagca
     3601 gtagccttcg gtgtcgcggt gctcctcgcc gcgctccccg gccaggccca ggtgtattcc
     3661 gacgcgccca cccagtcgcc tcgtggggga tccgtggagt tgcggctcgg cagctaccgc
     3721 ccgcagatcg acggggagga gggggtgagc ggcggtccct tcacggatat ctatggtgag
     3781 gggcgctggt ggctcttcga attggagttg caacgcttct tctaccaggg catcggcacg
     3841 gcggggctga gcctgtcggt gggctacgcg gagaagttcg gctacgccct gaccaaggac
     3901 aaacaaactc cgagctcgga gcggacgagc ttccacgtgg tgcccctgca cctgcggggc
     3961 gtctaccggt tcgactatcc ggcgttccag tggggcttcc cgttgattcc ctacgtcaag
     4021 ccagggctcg tcttcgtccc gtggtgggcc accaagggcg gcaagctcga cgaggcgccc
     4081 gcgacggagg ggtcggaggg gagcgaggga acgcccgcgc gcaagggccg cggtgtccgg
     4141 tttggctggg aagtggccgt cggtctgtcc ttcatgctcg acgtgctgga gccgcgcttc
     4201 gcgcgcgact tcgactcgga cctgggcatc aaccacagct atatcttcgc tgagtacacg
     4261 tactcgaaag tgaacagctt tggtcagccg ggtttgaact tgtcggactc ctactggatg
     4321 ttcggtctgg cactggatta ctaggcccta catgacactc cctccgtgct cctccgttcg
     4381 ggccctgatg gcggttctcg tggtggccgt ggcactgtcg ggtcctggtt gccgcagggt
     4441 ggtgaagccc gaggccggag gagatcgcac ggtggaggcc ggagtgccgg tggacttcgg
     4501 cgccgggggt caggatgccc ccgtggtgtc ctgggacttc ggtgacggct ctccggtcca
     4561 gtccggcacg cgggtggtcc acgccttcga gcgtccgggc acctacgcgg tgcgggcgct
     4621 ggacagggac gcggtgctgg cgagcgccac gctgacggtg gtgccccggc ccgtgttgcg
     4681 cgccatcccg gatgacgcgg aggtggccat cttctttccc caactgcgcg gcaacgtgga
     4741 tccgttgatg ggcttcatgt cgcagctggt gggcgagtcc caggtgttgc agacgctgga
     4801 ctcggttccc ctgctggcgc tggtgctgcg cgacgtgacg ggggggcagg cgcgcatcgt
     4861 ggatccggac gagggcctgg gcttcttctc cctgccgcgc ttcgagggct ccgtggtgct
     4921 gctgggcgtg acggacaccc aggccgcggt ggacgcggtg gtgaaggagg tgcagtcgcg
     4981 gggcgcccgg gtgatgaggc gcgagcccca gggcaccgtc ttcctgcggc gggacaatgg
     5041 catgtcgatg gtcgtttttc cggatcgcgg ctacctgtac gtcgtggtgc cggacgcgcc
     5101 ggagtcggag tccgagcagg aggagggcac gccgcagcag gtgctggcgg aggtgggcga
     5161 tgacggcctc gcggcggtgg aggaggtgcg cgcgcacatc cagggcgcga gtggctcggg
     5221 gctctccgag cagccgctgc tcacgtcgct gcgcgcgaag gtgggcgcgg gccacgtgca
     5281 cgtcttcgcc cgtcccgagg gcaatgacgc ctccgcgagc atccagggcc tgtgggcggc
     5341 gctgacgttc caggataccc gggcggacct ggagggctgg gtggtgtcgg acaagtcgct
     5401 cttccagggg gggacggcgc cgggctcgga gctgctggcc cgggcgcccc tggggcccat
     5461 cgccgcgctg acggtgtccc tgcctcccga gacgctggcg aagctcgtct tcggtgcgcc
     5521 cggctcggag cgccgcgcgc agaccgagca gcgcatggcg cgccaggggc tcgacgcggc
     5581 cggcgtgcag gggatgctgg gcgcgctgcg cggagacctg tcgttgctgg cctacctgga
     5641 cgcgccggcc ttctaccgca acctgctcaa gggcgcccgg ggtccggagc cgcgcggcag
     5701 cgtgttgttc caggcggggc tggtgcgttc cgagccggtg ctggagtggc tcaccggggt
     5761 gctcgagtcg cgcgggcagc ccttcgaggt cctcaaggaa aagggcgcca cgcgcctgcg
     5821 cacgcgcgtg ttcgagcagc cggtggacgt caccctcacg gcggaccggc tgacgctgcg
     5881 cgggggcgag tcgctggagg cgcgcgcgca gggcggggtg ggggaggagc tgcgccagcg
     5941 cttcggggcc cagggcttcg agccgggcca cctgtcggcc atggtggaca tgggccgggt
     6001 gcgctccgaa ttggattcac cccgggaggt gcccggcgtg ccgccgcagc agcttcccgt
     6061 ggcgcgtgcc ctggtgggca cgttgatcga tcaactgccg cccatcgaga gcctcttcct
     6121 cgacttcgcg cccgagcagg ggggcggccg tttccgcatg agcaccgtgt tgcgctcgcg
     6181 ctgaggttgc cgccgtgtcc tcactcacca ttctctattt cgccgcggcg cgggagcgcg
     6241 cgggactcgc gcgtgagtcg ctggaggtgc ccgccggcac gcgggtgggg gaggtgttga
     6301 gcctgctggc ctcgcgccac cccgggctcg cgccgctgct gccccacctg cgggtggcgg
     6361 tgaaccagga gttctccacg tccgagaccg aggtgccccc gggcgccgag gtggcgttga
     6421 ttcctcccgt ggcgggaggc tccggtgggt tgttccgggt ggtggaccgg ccgctgcgcc
     6481 tggaggaagt ggtggaggcg gtggccagcg aggcgctggg ggggctggtc accttctcgg
     6541 gggcggtgcg caaccagacg aagggccggc gcgtggtgcg gctggagtac gaggcctatc
     6601 cgcccatggc ggagaagaag ctggcggaga ttggcgccga ggtggccgag cggttcaacg
     6661 gcacgcggct ggcgatcgtg caccgggtgg gaacgctgca tccgggcgag ctggcggtgg
     6721 tgatcgccgc cgcggcgccc caccgcaagg aggcgttcct cgggtgcgag cacgcgattg
     6781 agcggctcaa gcaggacgtg cccatctgga agaaggaatt cttcgaggat ggtgaggtgt
     6841 gggtgggcct ggggccctga cgggggcgtc gtttgagcca tggtccccgg cgagaaaccg
     6901 tgagtatctt ccgcgccgga ggccatatgg ggttcgaact cgaggtcgat aactaccgcg
     6961 ccctgcgcaa gattcgctgg aaggcggagg gtgtctgcgc gctcgttgga cccaatggta
     7021 gcggcaagac gaccctgctg agcgtgctgc aatttctgag gcatgcgtgg attcaggact
     7081 ttggaagagc actgaatgca cacggcggtg ccctcctctt tcgtcaccgg caagcatcca
     7141 tccatgagcc agtccggttc gcactcgctg ttggaagcgc ccggtgggag gccgaaccct
     7201 ctacgagctt gctaggtgtt gttttcccag tgcccgaacg ccttatcgtc gataagaaag
     7261 tcgttgcgga acagcgagcg ggtgagtcgg gttttcgggt tctcgaggag aacaagaacg
     7321 ccgatggtca aagtttcctg gcctctgtag cggtggccag cccggagctg aggagcgcga
     7381 tggagcctct ggcggtcgct ctgtccgcct cggttctcta cagctttgat gccttctggc
     7441 aactgaagag ggaagggtca agagagggca cggatgtctg gctcagccag gacgggcgta
     7501 atgcgttcac ggtgatgcgc aactggatcg cggggaatag agcgtaccgg ccccgttggg
     7561 agtgggtgcg aagtggcctg cgggagtgct ttcccgactt gtttgatgac cttgacttcg
     7621 cggtcgctgg ccagactgtt gccgcccagt tctatggacc tggaggcgga gatccgacac
     7681 cgatgcacct cgctccgaac gggctcctca tggcgcttct gatactctgc gcggtcgcgt
     7741 cagcggacca tggcatggtc tgcatcgacg agccggagaa tggtcttcat ccgtatgcga
     7801 tacaacggct catctcgctc atgagggagc gcgctgaggc gcgtgggctg accattgtgc
     7861 ttgctactca ctcgccgacg ttgctgaacg agttcaacga ccaactggac cacgtcttca
     7921 tcatggagtc ggggcatgag tccctccccg tgaggctcga ccagcaccag aatccggagt
     7981 ggctccggaa cttcgcgctc ggcgacctct acatgaatca gacgatcgcc ccgcaggtcc
     8041 agccgaagac atgagccggg tgcagctcgt cgtgaccggg gagatggagc gggtcgcgct
     8101 cgcggcatca ctgcgccact ccttcccagc gcatgagctg gacttcctgc cgacgcagaa
     8161 ggtgcaggac ttcacctcga gcaggttggg aaatcacccg ggacgtgtac cggggctgaa
     8221 gacgcgcgcc caggagatgg ctcaagcgat cgtgtcggcg ttttcaccgg gcaggttcct
     8281 gaatgccatt ccagacctgg tgctggccgt cgacgatctc gaactggtca acgtggacca
     8341 gccgcacatc gtgacgacgt atctcgcgcg agaactcgaa ctcacgctca aggacaggaa
     8401 gttcctgccg gccgacgaga cgcgcgtgcg cgagctcctt cgccgccgcg cctcgttcca
     8461 cctcttcgtg cccatgcccg aggcctactt ctacgcggag tccgccgcac tcactcgcgc
     8521 tggagccaag gcggcgagcc gattcgacgt ggcccagcac gatacggaag ccttcgaggt
     8581 ggacgacccc gcctaccgtc aatggctcga aaagcgagcg cccaacgcgg tcgagcccca
     8641 ccgacacccc aagcagtacc tccggtacct gtgcgatccg agcgcgagtg ccgagcgggc
     8701 ctatcgggag accaaggaag gggcgctggc cctggaaaag cttgcctggt cggaggtgac
     8761 ggctcggcgg gcacgtgaga cctacgcccg agcactgctc gaggacttcg ccgatggcat
     8821 cggcgcgaac tggcagtcac ccggctccgt cgcaccactc accgcccggc ggagcggagg
     8881 gctcctccgg aatctcgcgc cggccgtgcc gccgacggca gccgttctcg gccagtagcc
     8941 cagagccgcc tcgtggtgga gcgcctcgct catctcagtg gatgccgaag ctgccaggca
     9001 gcgtccgcac gccggcgtcg ggcagggttt ctggggcgag gggacgtgcc ggggtgtcca
     9061 ccccgagccg cttgcgctcg gcctgctcct tctcgcgcgc ggcggcgagg gcgcgggcgt
     9121 tggactccgc catgtgctcg ggcgagtgcc ccgcgaggat caaccccacc gggatgctga
     9181 gcaggagggc gagcagcatc gcgagcagac ccaggtcgcg cgcgcccagt ccactcgcgc
     9241 gcttgcccgc caccgagggg gcgagcagca gggacaggtc tccctgggac aggcgcaccc
     9301 ggtcctccgc ggtgagctcc acccaggcac tggccccgga gcggcgcagc tccgtgtcgg
     9361 gcaccggctg gaaggcctcg cctcgccggc tgcgctcgac gcgcgaggcg ggtggcacga
     9421 agacgcggta gccctccggg gtacgctcgg cgatgaggaa gggctcctcc ggcagggtga
     9481 agccgtagag gggcaggggc accgtttcat ccggcgcggc gagcacgcgc gtctgctcgg
     9541 ggccgaagtt ccaggcctca ttccgggtgg ttccccaata cagctcgcag aacaggccgt
     9601 cgtggctcgc cttggtcttc atggcgtggg ggagcataga cggcccttgt ctccgtggct
     9661 ccattctatc ggtgcgattc ctccccgcga gccgtctcct ggttgcccgg gggacgagcc
     9721 ccgtgcgccg tgggctgact gtccgggcgg gcgggccccc gctcatcgtc acgggacgtg
     9781 gactcgttca agatggccat ggactttcac tctcatgtct catccgggag gtgattcctc
     9841 ggaggatggg aatcaggcgg ctcggctctg ggatgtgagg gcgccgtgtg ctttcttgtt
     9901 tttctcccat ttactcgtat tccatgatgt gcttgtttgc ccggcttgcg cccgggaggg
     9961 gggacgcctg tttcaatcca ccaggatgag gagttgccag atggcagcga gtgctgcgtt
    10021 ccatttcaat gacaagcaga tggtcgcgag ggttccgccg gacctgggga ccgtccgccg
    10081 ggagccccgg tacgcgcgcg tcgacgcgct catccagacg ctggtgggaa gggacgaggc
    10141 cgtcttcgac atccaggtgg atggcacgcg gcaccggatc gcctggccca tcgacttctc
    10201 cgaattccgt atcatcgcga gcacctatcc cgtgtccctg gacttgagca ggcgcgggca
    10261 ttttccggag ctggagaagc tccgtgcgca catgctccaa ggggatttcg atctgctcac
    10321 ctattacacg tgcagcacgg tctctccgct ctacctccag aacagtcagg atcggatgga
    10381 ctggttcttc gccctggact acttcgtcga tgggccgttg gtgccgccgg agctgcgcga
    10441 ggcggtggta cgcgacctgt cggcgtggct cgaggaccgg cgccacgtca gccggctgcc
    10501 gtgggtgaac atgatcagcg ccctgctgcg catcgtcctg gaggacatcg agcgcgaggg
    10561 gctcgacacc tcgcgcatcg tgcgggagat ccgcggctac tacgagggct tcctgctgga
    10621 gttcgacaaa caggtgccgc tcccgcgcta cctggagaac cggggcatgt cgatcggcat
    10681 gcggccggag ctcgagttct gcttcgccta ccagggcagg cccctgcccg cgcgcgatcg
    10741 ggacgcggcc gagcggatga agcacgccgc ggccgacctc gtcgcgttgc agaacgacgt
    10801 gctgtccctg cgcaaggagg aggagcagga gcaggagcac ctgcgcctga agtcctattt
    10861 ccccatcagc cacgagtacg tgtcgttcgc gaatgacttc tacgcggccc ggttcggcga
    10921 gttcctggcg atgcgtccac gcgcccccgg tcccctggag gctctctgga agatgtgcgg
    10981 ccagtggatc tccggcagtc tgctgtggca cctcaccagc cggcgctacg acctggggca
    11041 gttccaggtc ctagcgtgag tgccgttccc gctcgcccgg caggggccgt tccacgcgct
    11101 cgcgcaggga gccggcctcg aagggcttgt cgagtctctc caccgaggcc tccgcgagga
    11161 aggcccgcgc ccggtcggtg aaggctccgc ccgtcatgaa gatgacgcgc ggcaggtact
    11221 cgggccgccg ccgcgcgagc gccgcgtgca gatccatccc cgtcatgtcc cccatcatca
    11281 ggtcgcagaa cacccggtcg tagtctggct ccccgcacaa cagctcgagc gcctcgcgcc
    11341 cgctgtgcac caccttcacc tcgtggtggc gcccgagcac gcgcaccatc atcgtgccga
    11401 tggcgggctc gtcgtcgacg atgagcacgc gccggcgcgg cggcgccggg tgcttcacca
    11461 ccggaggggc tggcttcggg tccgtggcct cgtggatgac gggcagcacg agctggaagg
    11521 agctcccgcg tccgggctcg ctctggacct tcatctctcc gcccatgccc cggatgatgt
    11581 ccaggctgat gggcagtccc aggccggtgc cctcgccggg gagcttggtg gtgaagaagg
    11641 gctcgaagat gcgcgccagg acctccgcgc tcattccctt gcccgtgtcg cgcacctcga
    11701 gcaccacctg ggcgccctcc atccgggtca ccacggtgat ggcatggcgg atcgcgtctc
    11761 cctcggggat ggcctgggcg gcgttgatca acaggttgag gatcacctgg cccagcttgg
    11821 actcgttgcc cggcacgcgc ggcacgggca cgacgtggcg caccacccgg gcccgatggc
    11881 ggatgtgcgg catggccatg gacaggctga gctccagggc cgcgcccacg tccaccgact
    11941 ccgggggcgt gtcgctcgcg cgcgccaggg tccgcagctc cttcacgatg gcgcggatgc
    12001 gctcggcgcc cttgcgcgcg tcatccaggg ctcgggtcgt ctcgcgcagc cgctcggcgg
    12061 cggggggcag ctcacgtgcc agcgtgccga gctgctccag ggccacgtgc agattgccgg
    12121 tgacgaaggc cagcgggttg ttgatttcgt gccccacgcc cgccgcgagc tggcccgccg
    12181 ccatgagccc gccggagcgc accagcttct cctgggccgc cagcagttgt ctggactgct
    12241 ctcgcgccag ggcctccgct tcccgccggc ccgactgttc ccgctcgagc cgcgcctcgt
    12301 gctcccgcac gtcccgcacg agcgcggtga cgtcctgcaa gcgcacgagg acgccgtcca
    12361 gcaagggggt gaccgtgccg cgcaaccagc agtccgcctc ccgcagctcg ctccgcgcgg
    12421 cccgccgcgt ctccaccacc tggctcaaga gggcgaactg gctccgcagc gcctcggagg
    12481 cggcctcgct cagcctgtgc cccacgacga gccccggaca gacgcgcttc atgacgtcgg
    12541 cgtcgttgga gaagatgagc tcgaagtcga cgatggcctg ggtctcatcc cgcacggcgc
    12601 acagggccat gcagccctcc gggttgccct gctccagctc catcagggcg cgcaacagcg
    12661 tcgctcttcc cagcgtcagt tgcgcgtcgt cgctcccttg cttcaaggcc cgcatcccct
    12721 cttcatcccc attccctccc aaccctggcc ccgggagtcc atcaaaccgc tcccggggtt
    12781 ttcgcatccg ttaccaattc catgacttcg tgatttttca cgaaaaggaa gacgagcgcg
    12841 agagccggtg agcggatggc gtcgcgggga aggccgcccg tttggagcca gggctcagcg
    12901 gggagcgctc gccgcctcgg tcttggtgca agcgttcgtc ggagtgctgg cggcggtggt
    12961 tccggaaggc gtcggtggtg gggcggggca gtcgtccacg tgggaggggg tgccgggccg
    13021 ggttcccccc gcgttcttct cccagaggaa gagggggctg tcaccgggct cgcgcgcgtc
    13081 gaggccctgt tgggcacggc ccatgcgctg gcggagatcc gcgagcgaca ccgtcagcac
    13141 cacgcccagc agggcgacga agcccaccgc gtgcaccagc gtctccacgc gcgcgggcac
    13201 cttgcggccg ctgatcgact cgatgagcac gaacacgatg cgtcccccat ccagcgaggg
    13261 cagggggagc aggtggaaga aggcgagggc catggacagg ttgaccatca cccgcaggaa
    13321 ggcgcccagg ccgctgcccg ccgcccccga ggactgcttc accacgccca gcgggttggc
    13381 cagggcgatg ccctgcgtgc cgcgcagcag ccgctccacc atgcgcgcgc cctcgagcac
    13441 gaggttgccc gtgtgcgcca gtgcctgcag cagcgcctgg ccgggcgcgt gcgcgcggta
    13501 cacgtactgc tggctcacgc caatgcgccc cacgccccgc tcgtccagcc ggggccgcac
    13561 caccacctcg cgctcctcgc cctgacgctc gacgcccagg cgcagctcgc gtccgggccg
    13621 ccgcgcgatg agctccacga agccactcca gctctccagc ggctcgccat ccacgctcac
    13681 cagccggtcg ccgggcagca actgggcgcg cgccgcctcg gagccggggg tgatggtgcc
    13741 caccgtgagc ggcaccacga cgtgcgtgcc ggtggtgtag agcgcgaaga ggaccccgag
    13801 cgcgaagagc gcgttggcca gcggcccacc gagcagcacc agcagccgct tccaggggcg
    13861 ctgtgccggg aagctcgtgg agtccgtggg ctccaggccc ggtgcgtggg ggttcatccc
    13921 gtggatgcgc acggagccgc ccagcggcac cgcgcccagc gcgtagtccg tcccccgcca
    13981 ccgccaggag agcacgggcg gaccgaagcc gagcgtgtac cgctccaccc tcaggcccaa
    14041 cagccgggcg gccaccaggt gacccagttc atgcagcgcc acgagcaggc cgagcgcgag
    14101 gagcagggga aggtagtgca tctggggggc tcagagcttg cggcgctggc cggtgcgctt
    14161 gtaggtcagg tagtcggcga ggatggtgcc atggtcgaag cacagctcgc ggggcagggc
    14221 gtccaccggg aaggccttgg cctcggcggc gtcatccgcg ccccggggct cgccccgggc
    14281 ccggccgatg aagacggtgg agagggtgtg ccggcgggga tcccggctcg ggtccgagta
    14341 ggtgaagaac tgctccacca actccacgtc caggcccgtc tcctccttca cctcgcgcac
    14401 cgccgccacg tccaggcgct cgccctcgtc cacgaagcca ccgggcaggg cccagcccag
    14461 gggcggattc ttgcggcgga tgagcacgac gcgctcgccg gccaactcga tgatgcagtc
    14521 cacggtgggc acggggttct tgtacgaggc catggggcga cattctaacc cctggcctcc
    14581 ccattgcacc gcgcatgtgg gctcgcgctg cgttagcctg ctcgccgtgg cctcgctccc
    14641 tctgctccgc tggttccttc cgtgcaccct ggccctgggg ctggggggtg gctgtacccg
    14701 cgccaacctc cagaacgagg atcgctatga attcaccacc acggagctca tccgggatga
    14761 ctgtggcctg ctctcctcgg aggagtcgct ctgggacggc gagctgaaga tcgacggcga
    14821 tgtcgtgcgc atgacctctg actggcgggg cctgcagctc atcggcttcg tgcttccccg
    14881 cggcgagttc aacgatgacg ccttcgtgct cgatggcagc gagtccagcg cggccatcac
    14941 cctgcggggc aagcagtgcc tcgtggagca ggtgtggatg cacctggaag gcacgacgca
    15001 gtgcgccaca cgtttcgacg gcgtgttgag cgtgcgcatc gagccgcggg tggagcagcc
    15061 cgagtgcgcc tgccagctct gggtgaagta cagggcaatt caaggctctg ggtgccagta
    15121 ggaaagctct gcttgagact ccggacacga gccctctaga aagggggtat cccgacacgt
    15181 cacaccggag gaacgcatgg ctgaaacacc gcgtccgaac ccgcaggctt tggaatccgt
    15241 cctcgtggag aaccggctct ttccccctcc ggaggacttc tcgcgccgcg cgcacatcgg
    15301 cagcatggag gactaccgcc ggctgtggga cgaggcggag aagaatcccg aggcgtactg
    15361 gggcgcgcgg gcgcgcgagg agctgtactg gaaggagccc ttccagacgg tgctcgactg
    15421 gaagccgccg catgcgcgct ggttcgtcga ggggcgcacc aacctcgcgt acaactgcct
    15481 ggatcggcac ctgccggcgc tcaaggacaa gacggccatc ctcttcgagg gcgagccggg
    15541 agatcggcgc aaggtgacgt acggagagct gtcgcggcag gtgaatcagc tcgccaacgg
    15601 cctgcgcgcg ctgggcgtga agaaggggga ccgggtgggc atctacctgc ccatggtgcc
    15661 cgaggcggcg gtggcgatgc tcgcgtgtgc gcgcgtgggc gcggtgcact cggtggtgtt
    15721 cggcggcttc tcggccgagg cgctgctcga gcgcatgaac gacgcggggg cgcgggtgct
    15781 gctcaccgcg gatggcggct ggcgcaaggg cgcggtggtg ccgctgctgg acaacgtgcg
    15841 caaggcgctg ccgcagatga agaacctgga gcacgtggtg gtgctccagc gcaccacgca
    15901 gggggcgctg cgcctggagg gcaaggagca gtcctggagc gagctgaccc agaagcagtc
    15961 ggatgtctgc gagccggagt gggtggagag cgagcacccg ctgttcatcc tctacacctc
    16021 gggcagcacg ggcaagccca agggcgtgct gcacacgacg ggcggctacg cggtgttcgc
    16081 ctcgctgtcc tcgcgctggg tgttcgacct gaagaaggag gatgtctact ggtgcaccgc
    16141 ggacatcggc tgggtgacgg gccacagcta cgtcgtctac ggcccgctga tgaatggcgt
    16201 cacctcggtc atctacgagg gagcgctcac gcacccgggc gcggatcgca cgtgggagct
    16261 catcgcccgc gagaagatct ccatcctcta cacggcgccc acggccatcc gcgccttcat
    16321 gcgcctgggg gatgacatcc cgcgcaagca cgacatgtcc tcgctgcggc tgctcggctc
    16381 ggtgggtgag cccatcaacc cggaagcgtg gatgtggtac cgcgacgtga ttggcggcgg
    16441 gcgctgcccg gtggtggaca cgtggtggca gacggagacg ggcggcatca tgctctcgcc
    16501 cctgccgggc gcgacgccca ccaagcccgg aagtgccacg ctgcccctgc ccggcatcca
    16561 cacggaggtg ctcgacaagc agggcaagcc ggtgggggcg aaccagggcg gccagctctt
    16621 catcacccgg ccgtggccgt cgatgctgcg cacggtgtat ggggatccgc agcgctacgt
    16681 gaacacgtac ttcagcgagc tgcccggtgt gtacttcacc ggtgacggcg cgcggcggga
    16741 cgacgacggc tacttctggc tgatgggccg cgtggatgac gtggtgaacg tggcgggcca
    16801 ccgcctgggc accgccgagg tggagagcgc gctcgtcgcc cacaagtccg tggccgaggc
    16861 ggcggtggtg ggccgtccgg acgacttgaa gggcacggcg ctggtggcct tcatcacgct
    16921 caagaagggc gtgggccact cgccggagct caagaaggag ctggcctcgc acgtgggcaa
    16981 ggagattggc gccatcgccc ggccggatga gatccgcttc gcggaagggc tgcccaagac
    17041 gcgctcgggg aagatcatgc gtcggctgtt gcgtgacgtg gccagcggca agcagaccac
    17101 gggcgacacc acgacgctcg aggacctcaa cgtcctcgcg acgctgcgca gcgacgagga
    17161 gtagcgcttc ctcgcctccg ggcacctcgt ggccacgtct ggcatggcgt ggccacgggt
    17221 gacgccgaga cggggaggaa ggacacggat gatgagcgag tccccggatg tattggcggt
    17281 ggaggtgtcg cggcgctgtc gtgagaaggg cgtgcggttg gtgctggtgg aggcctgtac
    17341 gggcggcctc gtgtgtgcac ggctgacgga ggtgccgggc gcgtcgtccg tggtggagcg
    17401 cggtttcatc ccgtactcga acgaagccaa ggtggagcag ttgggcgtgc cgctggagtt
    17461 gctccaggcg catggctcgg tgagcgcgga ggcggtggag gcgctggccc acgccgcgct
    17521 ggagcgctcc cgcgcggact gggcggtggc ggagacgggc atcgcgggac caacgggagg
    17581 cacaccgcac aagccggtgg ggctggcctt cctcgcggtg atgcgccggg gtgggcgggc
    17641 cgaggtggag cgccatgtct tcacgggaga ccggagcgag gtgcgccgtg ccatctcgaa
    17701 ccgcgtgatg gccctgctgc tcgctcggct ggagtccgaa tcgtgagttt gcccaggacg
    17761 agttccaatt gcggcaccat gcccaacagc agatgccctt gcccgggctt gtgcaactca
    17821 tgcacgacgg aggacttgcc aatgcccgag tagccgcgga ccagcaccca ctccagccgg
    17881 ccgcgccccg ccttgcggcc cgttcatcga aggagtagtc gcgcctcctc acggaggagg
    17941 caccatgcga atcatcgtta ttggcgcaac gggcaccatc ggtcgggagg tcgtgcgggc
    18001 actgtccgga cggcacgagg tcatcgaggt ggcccggaag ggtggatgcc tcggggcatc
    18061 cgcatcaacg tggtgagccc gccgtgggtg gatggttcgc cccgggttgg gtgtcgggaa
    18121 tgggtgccaa atgaatcgtt ccgacatctc tcctgctagg agttgtctgg cagtttactt
    18181 ccgaggatgt gtcaaaccag actttcgctg ttttcagcta gccgagcgcc gcagttcatg
    18241 caaccctcgg ctgaagctgt gcatggggtg gtccactcca ccgaggttgg ttgggagtgc
    18301 agacaggtaa cgcaatgaag cgccggggat caaggcaatg tatccgtcag gcctgacacg
    18361 attgttggcg ctgctggcgg ccttggcaat tggtggcgcg ctctttcttg ttcccatcta
    18421 accctagact tcgcctccag agcaagaaac cgaaaggctc ggcgccgcca tgccctatat
    18481 cccagacttc gacacagagg cagtcctcca cattctcaac tcaatcatcc agaagcaccc
    18541 agagggatca ccggagagag acgcaatcga gcttgcgcag attgcattga tctacccccg
    18601 ccacatccgg aaagaggatg actttcgcag gttctacagg gacgtttatg atccctcatt
    18661 caagctaaaa gtctcccatg agttttcaac acgggaagag gcggatgaat ggctagccag
    18721 cgggaaggca gaggacgcag agcgcgtcag aatcgctgga aagggtttca tggttgtccg
    18781 actgcctggg aggtctacgt tcatgagcgc accccttgaa ggggaagagg aggaaacaga
    18841 cgaatcaggg gagggctccg agtaggcgat agtctggtga gggcggatgc tggagccgcc
    18901 agcagtgagc gctttggtct tgtccaagcg gatcgagtta cagtctcatc caccccatcg
    18961 ctccctgccc ccatcgattc agtatgtggg ggcttttttc atttcaagcc cattcgtgcg
    19021 ggtcagcggg tggtggggca gctcgatgat ggcctcggtg aactcgcctt cgcgagactc
    19081 caggcgcagg ctgccctggt gggtccccac gatgatgtcg tggctgatgg acagacccag
    19141 tcccgtgccc tctccgggcg gcttggtggt gaagaacggg tcgaacaccc ggttcaggtg
    19201 ggccgcggga atgccggtgc cgttgtcgcg gatgcgcacc tcgacgtgct cgcccaggtt
    19261 ccgggtggtg atgtccaggc ggggcgtgaa ggtcatgccc agcgcgagct tcttctggcg
    19321 cagcgcatgg ctcgcgttgg ccaccaggtt gatgaacacg cggctgagct ccgagcgcac
    19381 cagctccacc gcgcccaggc tcgcgtcgta gttcacgtgc acttcggggg tgatctcccg
    19441 gactccgctg cgcaggccgt gctgcaggag ggtgagactc tcggcgagca cggcgttgag
    19501 atccgagggc tcccgctcac tggcggcggc gcgggagtgg agcaacatgc cattgatgat
    19561 ctggttggca cgctggccgt gctcgtgaat tttctgggtg ttctgtcgca tcgtcgccag
    19621 cgtgctgctc atgtcctcat ggatgcctgg ctccatccgg tatcgctgtg agtcgaggct
    19681 cgtgctcagg tcctcggtga gctcgcccag cagctcgctg aagttgttga tgaagttgag
    19741 ggggttcttc agctcgtgcg cgataccggc ggtgatcgag cccagtgacg cgagcttctc
    19801 ctgggccacg agctgctgct gggtgtcacg cagctggcgc agggtctggc cgagctcctc
    19861 gttcttggtc tggagttcgt gcgtgcgctg ctccaccttc tgctcgaggg tccggctgta
    19921 gtcctccagc tgatcataga gcagcgcgtt ctgcagcgag agggccgcct gggccaggag
    19981 cgtgcgcagc acctcgagcc ggtcggcggt gaacgctccg tccgtcaggt ggttctccag
    20041 gtagagcagg gccacgcgct tgccctgggt gacgaggggg gcacacagca cggagcgcgc
    20101 ggcgtgctgg accacatagg tgtcggtggt gaagcggccc tcggccgcgg cgttgtcgag
    20161 caccacgctc tcgcccgtgc ggaccacgta gtggacgatg gccgaggaca atcgttcatc
    20221 tccctcgaac ggtgcgggga gcggggcgga ggcagggccc gacagcgagc gctcggccac
    20281 gatcgccagt cgtccgtgcc gctccatgag gagcagcccg cgctgggccc ccgcgttctc
    20341 gatggcgaac cgcatcaacg tgtcgaccag ccgctcgagg acgagctccc ccgagagggc
    20401 ctgggccgcc ttgagcaccg tggacgcgtc gagggcggag gtgctgccac ggctcgagtg
    20461 gctcggggcc tcggagctgg aggggttggc gtccgcccga cgggtgaaca cctgggggta
    20521 gcgctgctcc aggtcggcga ccttggcctc ggctccccag cggcggtagg cattggccgc
    20581 gtcgagcagg cagtcgcggg cgagccgctc gcgcccgagc gagaggtaga actccccagc
    20641 gagttcgtgc gcgagcgcca cgtcgttgag gtagcggttc ttcaaggcat tggcagcggc
    20701 ctcctcatac aggtggctgg cggctaccgt gtctcctctc aggcgggccc gctccgcctc
    20761 gacgagttgg tagcggtgca gcaggttcat gggcccgtgg tccgcccagt gcttcatctt
    20821 cctctggttc tgctccactt tctccagaag tcgctcctgc tcctcgggtg gcgcggtgcg
    20881 acatcgcaat agccatacca gtgcgctgta gtagtggaag atcacgaacg acaccgtgcc
    20941 gagcgacgac tggatgtagc tctccgcgtc ctccgccacc cgggtctccg cctgacggaa
    21001 gaagcactcc agcatgagct tctggacgta gatgagcgac tccatgtggg cgttctggt
//
