LOCUS       NZ_CP022098            25373 bp    DNA     circular CON 17-FEB-2024
DEFINITION  Cystobacter fuscus strain DSM 52655 chromosome, complete genome.
ACCESSION   NZ_CP022098
VERSION     NZ_CP022098.1
KEYWORDS    RefSeq.
SOURCE      Cystobacter fuscus
  ORGANISM  Cystobacter fuscus
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Cystobacter.
REFERENCE   1  (bases 1 to 12349744)
  AUTHORS   Rupp,O., Goesmann,A. and Sogaard-Andersen,L.
  TITLE     Sequencing and comparative analysis of myxobacterial genomes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12349744)
  AUTHORS   Bruckskotten,M., Treuner-Lange,A., Rupp,O., Goesmann,A. and
            Sogaard-Andersen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2017) Department of Ecophysiology, Max Planck
            Institute for Terrestrial Microbiology, Karl von Frisch Str. 10,
            Marburg, Hessen 35043, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 09-AUG-2016
            Assembly Method                   :: Celera Assembler v. 8.1
            Expected Final Version            :: yes
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/17/2024 10:04:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,093
            CDSs (total)                      :: 10,016
            Genes (coding)                    :: 9,906
            CDSs (with protein)               :: 9,906
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 26 of 110
            Pseudo Genes (incomplete)         :: 101 of 110
            Pseudo Genes (internal stop)      :: 1 of 110
            Pseudo Genes (multiple problems)  :: 17 of 110
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:24:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1399131
            Orig. end                         :: 1424504
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25373
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="6"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..25373
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25373
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:15373](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15373
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(363..373)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            406..1545
                     /locus_tag="CYFUS_RS05900"
                     /old_locus_tag="CYFUS_001173"
     CDS             406..1545
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023048.4"
                     /locus_tag="CYFUS_RS05900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001173"
                     /product="MopE-related protein"
                     /protein_id="WP_095984339.1"
                     /transl_table=11
                     /translation="MKSISSLVCALGCGLVMAVAASACWVPELPDGTVFSCDSNEDCTL
                     AGEKCVPRAGLSGYCCAPSANPTEVCNGVDDDCNGQKDDLAATTCYGGPAGTAGKGICK
                     AGTPKCGANNEQLCEGEVLPTAELCNRIDDNCDGVTDEGFDLQQDVKNCGACGTACAAS
                     QTCVAGKCMGRVQQVCTDGSDDDEDGLVGCADPDCTQKSCGTNRVCYGGKCGDIELVCS
                     DNVDNDQDGNTDCKDSDCDQKACGTGCVCKALAKAETACLDKLDNDGDGKIDCADSDCP
                     TDCGTGCVCNSNVATETLCGDGVDNDKDGKTDCADSDCANLSCGTGCTCKSNVAAETTC
                     NDGVDNDKDNKTDCADTADCPTGTTCGSGKTCRSNGTCS"
     gene            1814..3211
                     /locus_tag="CYFUS_RS05905"
                     /old_locus_tag="CYFUS_001174"
     CDS             1814..3211
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002628938.1"
                     /locus_tag="CYFUS_RS05905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001174"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_095984340.1"
                     /sec_met_domain="Pkinase (E-value: 4.4e-53, bitscore:
                     179.5, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVGDILGSYQLERLLGEGSMGQVFQARHVRLGRQVALKVLRSTY
                     AHDGNFVRRFFQEAHAVNQINHEHIVEIFDFVEDPAAGHVYCVMELLRGQSLSELLREE
                     RLSLARIRRLMVQVCAALSAAHQLGVVHRDIKPDNLFIAHKSGQTDFVKVLDFGVAKLL
                     TAEGVNGTLDGTIIGTPTYMSPEQAAGLPVDARADIYAVGTVLYELLAGQPPFVAPNFG
                     QLMVKVLTESPPELPTHTPAGDAIPPELARITLRCLSKEPEGRPAQLAEVITALLMDSD
                     AATLAVVPPEDRPTRPMPMPFALRMPRRAGWVAMAGVLAMAGVGLVLTRGGEPAVSPPV
                     SGVAEPRVAEASKPQPVPVSLTVNSVPAGARVVRADTGETLGVTPWVAQMPSSAGSLGV
                     RVELAGYVPSEHQLRLDTSSSLEVPLVRAGTKPARATPSRSSLPRSSLSRKSSMGNRDA
                     VIDPFAP"
     gene            3183..3824
                     /locus_tag="CYFUS_RS05910"
                     /old_locus_tag="CYFUS_001175"
     CDS             3183..3824
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002611589.1"
                     /locus_tag="CYFUS_RS05910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001175"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_232537394.1"
                     /transl_table=11
                     /translation="MPSLIRSLLERSGWWVAVVVGLLALAPLSARAQGGEARAQAQARA
                     KFLEGNAAYEQAQFQKALDAYVEAYRLLPLPGFLFNIAQCYRQLGQPEQAATFYRRYLA
                     QSKQPPANAPLVRELIAEMDAAVGKPQQKDSSLRKQTAEVAERRARQDSERSRTVASRS
                     TPAQTEVQGESLAKKWWVWAGAGAVAIAAGGIIYAATAPQPRPTTLGTIR"
     gene            complement(3850..4392)
                     /locus_tag="CYFUS_RS05915"
                     /old_locus_tag="CYFUS_001176"
     CDS             complement(3850..4392)
                     /GO_function="GO:0051219 - phosphoprotein binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002611566.1"
                     /locus_tag="CYFUS_RS05915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001176"
                     /product="FHA domain-containing protein"
                     /protein_id="WP_095984341.1"
                     /transl_table=11
                     /translation="MARSLLMSLLVRQHLALKEKFRARYPHSWLVWEAGVWNVPESSEQ
                     NHGATRLPTSDLRDCLPPGDAMCFELTPGRDELMIGRASHNAFVINDATVSREHLLLRA
                     RPDGGWTVEALSQGGPVMLGGELLPPGQPRPLESGMHLQLGDVRLTFHDAESFHQRMGH
                     AAALVMAQMRGSPNSPA"
     misc_feature    4400..4414
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.72"
                     /tool="antismash"
     gene            complement(4503..5705)
                     /locus_tag="CYFUS_RS05920"
                     /old_locus_tag="CYFUS_001177"
     CDS             complement(4503..5705)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011554210.1"
                     /locus_tag="CYFUS_RS05920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001177"
                     /product="metallophosphoesterase"
                     /protein_id="WP_095984342.1"
                     /transl_table=11
                     /translation="MAIPTRLLVFFALLSITVVGGHLYLYRRLFRDTGRHPHWRRMGVV
                     LMGVLGASLLVSRPLMALAPSAAASAFAQGSWYWMGVAAYLLLTMLAVGGARTLAGWIG
                     RRRPAPAAPAGNAALVSEERREFLARAGAGVALVATGGITTYGTWRAFHPPVVNEVTVK
                     LPGLPKALDGITIVQLSDIHVGPLIQRRFMDELVARTNALKGDLVCITGDLVDGSVERL
                     GHAAAALGELRSRFGTYFCTGNHEYYSGDEEWTEALTRMGVTVLRNRHVRVGDAGASFD
                     LVGVDDWAAARSGYPERGYDLSAAIAGRDPTRASVLLAHQPAGWRDQAQKAGMGLQLSG
                     HTHGGQMFPFTLAVSAIWEHDAGLFREGDHSLYVSRGTGFWGPPVRVAAPPEIVKVTLL
                     A"
     gene            complement(5783..6688)
                     /locus_tag="CYFUS_RS05925"
                     /old_locus_tag="CYFUS_001178"
     CDS             complement(5783..6688)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631660.1"
                     /locus_tag="CYFUS_RS05925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001178"
                     /product="TIGR01777 family oxidoreductase"
                     /protein_id="WP_095984343.1"
                     /transl_table=11
                     /translation="MKVAISGASGLLGPPLVQRLMDAGHAVHVLARDVKRALGRLPPGV
                     TGSFFDATTPLSPEALAGAEAVVHLAGEPVAQRWTAAARQRIQDSRVVGTRLLVEAMRT
                     AGTVRGFVSASAIGYYGADRGEEPLTEMGAPGGDFLARVCQGWETEALEAERAGIRTVV
                     ARIGVVLHPSGGALETMLPLFRLGVGGRMGSGRQYLSWVHLEDAVGLLHHALEREDLRG
                     PMNVTAPEPVTNARFAQALGAALGRPALVPVPAFALKLALGEMSVTALGGQRVLPERAR
                     ETGYVFRHPELSEALRSLLG"
     gene            complement(6699..7178)
                     /locus_tag="CYFUS_RS05930"
                     /old_locus_tag="CYFUS_001179"
     CDS             complement(6699..7178)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002611537.1"
                     /locus_tag="CYFUS_RS05930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001179"
                     /product="hypothetical protein"
                     /protein_id="WP_232537395.1"
                     /transl_table=11
                     /translation="MNATLWDSHGKEVDLSRWRGKPVILFYEDRHSTTLNASLKDALFN
                     RGREMGLLQAAWVVAVANLESFNFFPARDIALSHVRGEEKKWGVPILVDLKGVLGDAPW
                     KLPKKTSSVMLLSADGRVVYSYSGRMDQEDMEVFFGHLGTLLGRDMTGAPRDAHP"
     misc_feature    complement(7297..7314)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.89"
                     /tool="antismash"
     misc_feature    complement(7299..7319)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.82"
                     /tool="antismash"
     gene            7376..8446
                     /locus_tag="CYFUS_RS05935"
                     /old_locus_tag="CYFUS_001180"
     CDS             7376..8446
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013935940.1"
                     /locus_tag="CYFUS_RS05935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001180"
                     /product="farnesyltranstransferase"
                     /protein_id="WP_095984344.1"
                     /transl_table=11
                     /translation="MGPTPFIAAAPRLAPSVERTWLALVRAQVEGVLDELLVLPDEARL
                     DEGWARALGQTRAQLSRSPQQMRPALLLAGYCLARGSTVVPAGLWRFVAGLELLHASRA
                     LHSDVLAFSRPRPEGAPLHARLAPGPAGGHLAVVVGDHLFARALEVMMEADVPGAVQAS
                     QYCLRMDRSTVPGLFRREQGGLLAEQGGVRQALRLARLRMVREGLATSLVCGAMLAGAE
                     ESLRLRLAGVGCGLGLATLLRQESASLLEVPWGGPGDFVLGRCTFPLMAAWSRSRPEAR
                     AELEALWNLPREQKDAAVLSRVRVLVDEAGGRSATERIAARAAHGAVRALSTLPNPQGL
                     RDLMRALVGPSSQPMV"
     gene            8460..10004
                     /gene="crtI"
                     /locus_tag="CYFUS_RS05940"
                     /old_locus_tag="CYFUS_001181"
     CDS             8460..10004
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631666.1"
                     /locus_tag="CYFUS_RS05940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001181"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_095984345.1"
                     /transl_table=11
                     /translation="MERGKRQAVVVGAGVGGLAAAARLAHAGFSVHLFEKTDGPGGRCN
                     QLKVDGFTWDLGPTIVLMPEVFEETFTALGRRMEDYLTLHRCDPNYRIHYRDGSAITFT
                     SELCAMGRELERVEPGSYQRYLSFLALGRTQYRTGLDHLVGRNYEGLSDYFVPSVFKRI
                     LEVRAHRRMYSEVGRFFKDERLRAGMTFQSMYLGVSPYAAPGVFALLPFTELGVGVWFP
                     QGGLYAIPLALEKLAREEGVHLHYGTPVRRILTEGKRTTGVELEGGEVVRADVVVCNAD
                     LPYAYEKLLDKNVTRLKRADKLRYTSSGYMLYLGMRRRYDEFLHHNVYFGNDYKGSFDS
                     IFEHFRVPEDPSFYVNAPAHTDPSLAPPGKDALYILVPVPHQHEGLDWKTEGPRVRAKV
                     FQRLAELGHTELERDIEVERVLTPDDWASTFNLARGSAFGLAQNFFQIGPFRPSNQDPR
                     VKNLFFVGASTQPGTGLPTVLISARLAVERILTWAGVDNVVRAPGGTGPGSMEEAA"
     gene            10001..11035
                     /locus_tag="CYFUS_RS05945"
                     /old_locus_tag="CYFUS_001182"
     CDS             10001..11035
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631675.1"
                     /locus_tag="CYFUS_RS05945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001182"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_095984346.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.3e-68, bitscore:
                     229.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 9.7e-72,
                     bitscore: 240.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSRDENLVAKGYRMAEQVTRHHAKSFFFASFMLFGMRRKAAFAL
                     YAFCRRLDDMVDVADGADKGAVPTDLAERLTRARRAVAELFLDTPELADPRLPPPATRA
                     SGGEGPWHPAELAALVDCIQRFRVPEYPMQELISGMEMDLTIRRYDTWSQLDLYCYRVA
                     GVVGLMMAAMLGCSEEWALGPAADLGRGMQLTNILRDVGEDLERDRVYLPLEELAAFGL
                     SLEDLRRGVVDDRWRDFMRWQISRARAYYERAAAGIPALSGFGSQRMVMLMGSIYGDIL
                     RVIEERDFDVFSGRSAVSKSRKFALATHALVRPATVPLMHVRAPGGSVPLLPPARAVTT
                     GSMP"
     misc_feature    complement(11056..11070)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.67"
                     /tool="antismash"
     gene            11061..12518
                     /gene="crtI"
                     /locus_tag="CYFUS_RS05950"
                     /old_locus_tag="CYFUS_001183"
     CDS             11061..12518
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000024: Halogenation (61% identity)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013377645.1"
                     /locus_tag="CYFUS_RS05950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001183"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_095984347.1"
                     /sec_met_domain="DAO (E-value: 6.1e-13, bitscore: 48.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSMRVAVVGGGIGGLTAAGLLAREGHDVTLFEGGPHLGGKAQSV
                     QVGGLRLDTGPTLLTLPDVVRGLFDSLGAADLLPPFLELEAQCTYHFADGCGFVASKDL
                     ERTAHSAAQLRPSEGKGVHGFYAEAEHIWRAAGEPYLEAPFEGMAGFMSRVLRRGMVAV
                     ARGMKLSTLDDLARAHFKTEYMWQFVGRFATYAGASPYAASAAYALVPHIERAYGVHHV
                     RGGIGALVDALGAAVARLGVKVHLNTRVHYQREGHGYRVGPSGGEERFDSVVVNADPLD
                     KLGRGSEPLSLSGHVLLLEVDGRPALPHHAVLFSRDYRREFDELFAGQLAADPTVYFCN
                     PSATDDTVAPPDKTGLFVMVNAPALPREPGAAERAAAEWELHGERVKAQMFDKLLTHYP
                     ELKGRMRVVAQRTPVDLAALGAPGGSIYGFLPHGRFGPFRRPRIRGGTPGLFFAGGGTH
                     PGGGVPLVMLSGQFAARMASAHLRSGE"
     gene            12515..13486
                     /locus_tag="CYFUS_RS05955"
                     /old_locus_tag="CYFUS_001184"
     CDS             12515..13486
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631679.1"
                     /locus_tag="CYFUS_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001184"
                     /product="carotenoid 1,2-hydratase"
                     /protein_id="WP_095984348.1"
                     /transl_table=11
                     /translation="MRRLDLLSPRALRGESWLDALPALPDTAGAYRWFYADVTAGEYSA
                     VFIFMLGSLFSPRYSVGAPRGALPLQHSAVNFALYHRGRGVRWVLSEYPQALVCQGGRE
                     LLIGRSRLEYTRDGRVCLEVDEQCAPFGGAVHARLELQPESFSTEEVQLVPGVPHYWRA
                     LAPRARAWLSVDSEDVRAEGHGYHDTNHGAELLGARLPGWYWARLHGPEETVVEYHLPG
                     GVAPLRVTASARGTSCERWPVRAEPLGTRMTGWGLRVPERLVSSPGGATEPRLLESSPF
                     YARLEARQGGLDVMGEVADFRRFHSPFIRWMAHFRTRVERQT"
     gene            13483..14619
                     /locus_tag="CYFUS_RS05960"
                     /old_locus_tag="CYFUS_001185"
     CDS             13483..14619
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631680.1"
                     /locus_tag="CYFUS_RS05960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001185"
                     /product="glycosyltransferase"
                     /protein_id="WP_095984349.1"
                     /transl_table=11
                     /translation="MTTWAALAMAWGGLAGGFSAVALARLMRRRPAAASTRVPVLLLRP
                     VDAPTPREVENLATPIDYPGPLEHVVLAPERPPLPEHVRWVPSDPSTPNRKVGHLLHAL
                     RVLPREGRVVLVVDADVVVTGALVAGLAAPVAAGAALSTAVPTPVDARGLAGRAVAALL
                     RRTHHSFRALHVMSAGAAAVCGKALGLSGRAVEELPELADHIGEDLELSKRLHARGLGV
                     ALCEVPAVVPLAAGDWDAALARFTRWMQVLRSHRPGLYPTVPLLFTPTWPLLVLGMAAG
                     SSGLWGCVAALVAVRTLLSWRLARLSAPGAHPGAGSSEGGAYSFALDWLLGEALLLAAF
                     VRSLAHPPRVTWRGRVYALHPGGRMSPGWTELKQEGGV"
     gene            14616..15029
                     /locus_tag="CYFUS_RS05965"
                     /old_locus_tag="CYFUS_001186"
     CDS             14616..15029
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631681.1"
                     /locus_tag="CYFUS_RS05965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001186"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_095984350.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 1.4e-19,
                     bitscore: 69.6, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYARFLGLFVVLPIVLLAVRYRRVLTGRALLPLVPLLAIVYVAT
                     CPWDNLAVKWGLWRFKPELIWGIVVGYLPLEEYLFFGLQTLLVGVWVLARLRRVSLAPA
                     ARKSPASPPVPAGQHRLDSKLGSNKLGSKEVVS"
     gene            15026..15373
                     /locus_tag="CYFUS_RS05970"
                     /old_locus_tag="CYFUS_001187"
     CDS             15026..15373
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631682.1"
                     /locus_tag="CYFUS_RS05970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001187"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_095984351.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 3e-19,
                     bitscore: 68.4, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMESRWAYLIHLMAWAGPFIALQLGVLVFYFRERSWTVLRAALVP
                     AGVMGVYLSVADHLAIREGIWSFGEGKHLGIYIGAVPLEELLFFLLTSVMVALGLTLFA
                     ALLARREARVP"
     gene            15370..16044
                     /locus_tag="CYFUS_RS05975"
                     /old_locus_tag="CYFUS_001188"
     CDS             15370..16044
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014393638.1"
                     /locus_tag="CYFUS_RS05975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001188"
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="WP_095984352.1"
                     /transl_table=11
                     /translation="MIHAAKGGFPGWMVDTYVGWKFRSSFRGLWVRGALEDSVAGRLVY
                     ANHSNWWDGFVLHQLGRAAGWDTYCVMEEKNLARYRFLSRIGAFSIRRGEAASSLETLR
                     YASSLLARPRAAVCIFPEGELRPHGVRSLKLERGVELLARVSGARCVPLCIRYAFFEHE
                     RPDVLVEVGGSHAAAPLERYREELEAAARRLEAATSLEGFTQVVSGARGVAERWDAVRG
                     HG"
     gene            16037..16939
                     /locus_tag="CYFUS_RS05980"
                     /old_locus_tag="CYFUS_001189"
     CDS             16037..16939
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631684.1"
                     /locus_tag="CYFUS_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001189"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_095991828.1"
                     /transl_table=11
                     /translation="MAERTYRIHIAAEFSGVKVELIRAWERRYGVLSPQRTPSGYRVYT
                     DRDVALLRRLKQLTEEGVSISEAAKMLPQLLAEIDAAQPSQSPPPEPSDGSVASWREEV
                     LEAVRVLDQRRVSETLDEVLAALSPLKAYEDVLVPLQQEVGELWHQGVFTVGQEHLVTQ
                     EIRARLISLLYSAPNKGPRHALLACFPEEQHELGLLGMALRLRHSGMTVTLLGQRTPTD
                     EVVRIARALEVDLVGLSAVVDPGAREFEEILTRVTRGLTPGMDVWVGGRAALQHRALCE
                     RLGVRVFEHAADWPRLLGG"
     gene            17046..18386
                     /locus_tag="CYFUS_RS05985"
                     /old_locus_tag="CYFUS_001190"
     CDS             17046..18386
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014081.4"
                     /locus_tag="CYFUS_RS05985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001190"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_157758267.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 3.1e-14, bitscore:
                     52.1, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLGVCFLFLCLAVPLPGCVHDSGSGPARSDEAVAFIGVNVVPMD
                     SERVLPDQTVIVRDGLISAMGPSTAITVPAGARRIEAKDRYLMPGLSDFHIHLHSDEQL
                     LSYLAHGVTTVFELNGTPRHLKLREQIARRQVLGPRLYTSSPLMDGGPEGGSVVSVNSP
                     EQARQAVVRQKREGYDAIKVYDNVPPGVYEQLVATAREQKLPVMGHVPRRVGVDAVLRA
                     RQAFISHGIEYFLAGSRDESRIPGFALGTKAAGTTVVPDLSHVHTSLKMMEDLEGVFSD
                     PEARYLSPKVMSDWRYSNPTRRVDVRQFSERQRAAYPFVQHLTLSLQKAGVRLVLGTNA
                     SDAGLFPGKTVHLELAELVRAGLSPYEALVTSTRNPAAFIEEHVDPAARFGTVAVGQHA
                     DLLLLPGNPLEDVGQAGQALGVMVRGQWLTREHLQRLRDKVAESFNR"
     gene            complement(18462..18872)
                     /locus_tag="CYFUS_RS05990"
                     /old_locus_tag="CYFUS_001191"
     CDS             complement(18462..18872)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019013.4"
                     /locus_tag="CYFUS_RS05990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001191"
                     /product="ester cyclase"
                     /protein_id="WP_157758268.1"
                     /sec_met_domain="PF07366 (E-value: 1.9e-26, bitscore: 91.5,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAAKARQFYEDFLNTLYIQRNVGRLGDFIAANIVSHPVYPGQTP
                     GIQGFEQMTRAFLDTFSDISFRVDGFSQEGETFSCQLVMKAKHIGTFMGIPATGRTAEV
                     VDNLRYRLENGKIVEYWSNVDTQSLQRQLSAA"
     gene            complement(19645..20076)
                     /locus_tag="CYFUS_RS05995"
                     /old_locus_tag="CYFUS_001192"
     CDS             complement(19645..20076)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025451.4"
                     /locus_tag="CYFUS_RS05995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001192"
                     /product="DUF4265 domain-containing protein"
                     /protein_id="WP_095984355.1"
                     /transl_table=11
                     /translation="MNERLKLRFPFENAEGEEEAETLWVIKREDGYEIDNIPFYAKEVS
                     LGDVVAAQPDAGGVLWYSELVRPSGHSTLQLWFSRQEDVESVREALRQRGCASELSDLP
                     RLVAVDVPPHVPYANIKALLEQGEQAGQFEYQEACLGFN"
     misc_feature    complement(19708..19710)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(20073..20576)
                     /locus_tag="CYFUS_RS06000"
                     /old_locus_tag="CYFUS_001193"
     CDS             complement(20073..20576)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013964.4"
                     /locus_tag="CYFUS_RS06000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001193"
                     /product="HNH endonuclease"
                     /protein_id="WP_157758269.1"
                     /transl_table=11
                     /translation="MFTPRSLVPKVHLFFAATVLALAVPFSVQATNTRIHPEPASSLVA
                     PLTFVAVEKQSALRSSSSQLNIVAGKAMRGSSGGARSGKAFTPAGKREIDAANAAKNNG
                     SNKCENCGEDVVPAKKNERGVSPPVNQRERDHIIPKSKGGDGSPSNGQVLCRECNQEKG
                     DKSP"
     misc_feature    20608..20621
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.57"
                     /tool="antismash"
     misc_feature    complement(20610..20625)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.21"
                     /tool="antismash"
     misc_feature    complement(20611..20620)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    20740..20754
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.15"
                     /tool="antismash"
     gene            20902..22440
                     /locus_tag="CYFUS_RS06005"
                     /old_locus_tag="CYFUS_001194"
     CDS             20902..22440
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002617184.1"
                     /locus_tag="CYFUS_RS06005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001194"
                     /product="hypothetical protein"
                     /protein_id="WP_095984357.1"
                     /transl_table=11
                     /translation="MLTIALRKAGGHIQVLEAIAFKGQPEGDAFCPSEDCGQPLVPVSA
                     FVRVGNIPVRAFFRHRRGTAAKRPCWGAKGEGGLHFAAKLHLRVRLQELCEKGGALVVE
                     QPCLRCAVGLSHEVLRTKPSDVVRIEHWLDPRRTLRPDVVLLRAGVPLLSFEVRASHPC
                     SPKKIAALTVAGAQMVEVEAWVLLGTETTLTWYPSVPLPLKRAVLPVARQLCPDCQTAQ
                     DFEAACERAAEERRQREREEQQRCDAQRAREREEQQRRDELCARERQTEWACDAQRAHE
                     MEVQREDARPVLRVQEEVARAKIAATPRLGTLPLNPRLHAAAPNVEVLAHCFVDVCRPD
                     GVRDELELVLERAVGGPLKAQLVERRAKNPKQVQLHAQSDRRLLMEWWGTAVTDTDSLL
                     QKARAAASAEYKVERDAGCIVDPHGGFRLGAADVSAWPHPNHWWEERAQRWVRARLRHM
                     LADELKVSENAVDERLPARYFHRILVRFKRNKRDFAAYEAVGNATFDDWLRGGT"
     gene            complement(23195..24721)
                     /locus_tag="CYFUS_RS06020"
                     /old_locus_tag="CYFUS_001196"
     CDS             complement(23195..24721)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631696.1"
                     /locus_tag="CYFUS_RS06020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001196"
                     /product="peptide MFS transporter"
                     /protein_id="WP_095984360.1"
                     /transl_table=11
                     /translation="MTMTTAPSLSGESAAPPLATRGFFGHPRGLATLFFTEMWERFSFY
                     GMKALLILFMTETAARGGLGFDTAKASAIYGLYGSAVYLTALPGGWLADRFIGQRRAVL
                     VGGIIIALGHFSMAMTGVAFFYLGLVLIVTGTGLLKPNISAMVGGLYPEGGARRDAGFS
                     IFYMGINIGVSVAPIVVGLLGERVSWHAGFGVAGVGMVLGLIQYVAGARHLGDVGLSTR
                     GSTEPSAEAPRAGSRGLVLGVGAVLVVLLGVLQGLGVVDMTNAVGLGDAAGFVIVALAL
                     AFFGYMFAAGGLEAADKRRLAVIGVFFLSSTVFWAGFEQAGSSLNLFARELTDRDVFGW
                     NVPASLLQSINGVFIITLAPVFAWLWVWLNRRGHEPSSPAKFSLGLVMLGAGFLVMVGA
                     SLAAAGGHRVSPMWLVLTYLLHTFGELSLSPVGLSTVTKLAPPRTVGMMMGVWFMSMSL
                     GNLIAGRVAGQFEAMPLPQLFGAVAAVAIAAGLLLALFVKPLRRMMGGVN"
     gene            24929..25357
                     /locus_tag="CYFUS_RS06025"
                     /old_locus_tag="CYFUS_001197"
     CDS             24929..25357
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002631697.1"
                     /locus_tag="CYFUS_RS06025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_001197"
                     /product="hypothetical protein"
                     /protein_id="WP_095984361.1"
                     /transl_table=11
                     /translation="MPVPQNVATDYGFRSTAPGYIIPAEARLWFEDLKARVLRLEGRPF
                     GLLVDSRTQKSNPPESQEIIRDAMVWLRDHGMQRSVVVLDSTVALIQILRIAKSTGVYS
                     YERYLDALKEPQWERKAVDWLAHGIDPDLPPPSPSREG"
ORIGIN
        1 ggagctggac gagcgcacgc cggcgaagaa gaagaagtcg ggctcctcga atcccaccat
       61 cttcagccgt cccgccctct acaccacggt gctgggactg gcggcggtgg gcgcgggcgt
      121 ggcgatgggt ctgcccctgc agcagaggac gctgaagata gaccgccagg gcgtggtgga
      181 catccaccgg ggcgagtacg cgtccatgcg gcagcaagcg ctgatctcca cggccctcat
      241 ggcgggcgga ggcgcggtgg ccgccggcag cctggcctgg ctcatcatcg tgccgcagcg
      301 ctccgcgccg gcgtcttcct ccgtggctcc ggtggccggt gggacgggcg gctcggggcg
      361 cggtgacatg gcccttcatc tcgtgtttgg tgggagcttc tgaccatgaa gtcgatttct
      421 tctctggtgt gtgcgctcgg gtgcggcctg gtgatggccg tggcggcctc ggcgtgttgg
      481 gtgccggagc ttccggacgg caccgtcttc agctgtgact cgaatgagga ctgcaccctg
      541 gccggggaga agtgtgtgcc ccgggcgggc ctgagtggct actgttgcgc gccctccgcc
      601 aaccccaccg aggtgtgcaa tggcgtcgat gacgactgca atggccagaa ggacgacctg
      661 gccgcgacga cctgctacgg cggccccgcg ggcaccgcgg gcaaggggat ctgcaaggcc
      721 ggcacgccca agtgcggcgc caacaacgag cagctgtgcg agggcgaggt cctgcccacc
      781 gccgagctgt gcaaccgcat cgacgacaac tgcgatggcg tgacggacga gggcttcgac
      841 ctgcagcagg acgtcaagaa ctgcggcgcg tgcggcaccg cctgcgcggc gagtcagacg
      901 tgcgtcgcgg gcaagtgcat gggccgcgtg cagcaggtgt gcaccgatgg ctcggacgac
      961 gacgaggatg ggctcgtggg gtgcgcggac cccgattgca cccagaagtc gtgcgggacc
     1021 aaccgcgtct gctacggcgg caagtgcggc gacatcgagc tggtgtgctc cgacaacgtg
     1081 gacaacgacc aggatggcaa cacggactgc aaggactccg attgcgacca gaaggcctgc
     1141 ggcaccggct gtgtctgcaa ggccttggcg aaggcggaga ccgcgtgtct ggacaagctg
     1201 gacaacgacg gggatggcaa gatcgactgc gcggactcgg actgcccgac cgactgtggc
     1261 accggctgcg tctgcaactc gaacgtcgcc accgagaccc tctgcggcga cggtgtcgac
     1321 aacgacaagg atggcaagac cgactgcgcg gactcggatt gtgccaatct gtcgtgtggg
     1381 acgggctgca cctgcaagtc gaacgtcgcc gccgagacca cctgcaacga tggtgtcgac
     1441 aacgacaagg acaacaagac cgactgcgcg gacaccgccg actgccccac ggggacgacc
     1501 tgcggaagcg ggaagacctg caggagcaac ggcacgtgta gttgatccac ccaggtgatg
     1561 cggtatccca agcccttctt cttccgggaa gaagggcttt tcacactccg ggccaacccg
     1621 gtgccccacg agggcaggtc aggtgggcaa aagtcgccca cctgacggcg ctgttcacgt
     1681 atgggttgcc gggaacagat tccgtggcga gtttggtcct ctcatgggcg gcgacgacct
     1741 catcccaggt actgtactct ccactggctc gcgcaacgcc ggacccggcg gttcctcgat
     1801 tcaggagacg cagttgcagg taggcgacat cctgggcagc tatcaactgg agcggctcct
     1861 gggtgagggc tccatggggc aggtcttcca ggcgcgccat gtgcggctgg gacgccaggt
     1921 ggccctcaag gtcctgcgct ccacctacgc ccatgacggc aacttcgtgc ggcgcttctt
     1981 ccaggaggcg cacgccgtca atcagatcaa ccacgagcac atcgtggaga tcttcgactt
     2041 cgtcgaggac ccggcggccg gccacgtcta ctgcgtgatg gagctgctgc gcgggcagag
     2101 cctgtcggag ctgctgcgcg aggagcggct gagcctcgcg cgcatccgcc gcctcatggt
     2161 gcaggtgtgc gcggcgctca gcgcggcgca tcagctcggg gtggtgcacc gcgacatcaa
     2221 gccggacaac ctcttcatcg cccacaagag cggacagacg gacttcgtga aggtgctcga
     2281 cttcggcgtg gccaagctgc tcaccgccga gggcgtcaac gggacgttgg acggcaccat
     2341 catcggtacg cccacgtaca tgtcgcccga gcaggcggcg gggctgccgg tggacgcgcg
     2401 cgcggacatc tacgccgtgg gcaccgtcct ctatgagctg ctcgccggac agccgccctt
     2461 cgtggcgccc aacttcggcc agctcatggt gaaggtcctc accgagtcgc ccccggagct
     2521 gcccacgcat acgcccgcgg gcgatgcgat tccgccggag ctggcgcgca tcaccctgcg
     2581 ctgtctgtcc aaggagcccg aggggcggcc cgcgcagctc gccgaggtca tcaccgcgct
     2641 gctgatggac tcggacgcgg ccaccctggc cgtcgtgcct cccgaggatc gtcccacccg
     2701 gcccatgccg atgcccttcg cgctccggat gccgcggcgc gcgggctggg tggccatggc
     2761 gggtgtgctg gccatggcgg gcgtgggact cgtgctgacg cgaggtggcg agcccgctgt
     2821 ctccccgcct gtctccgggg tggccgagcc gcgggtggcc gaggcctcca agccccagcc
     2881 ggtgcccgtc tccctcaccg tgaactccgt gcccgcgggc gctcgggtgg ttcgcgccga
     2941 cacgggcgag acgctcgggg tgacgccgtg ggtggcccag atgccctcct cggccggctc
     3001 cctgggcgtg cgcgtggaac tggcgggcta cgtgccgagc gagcaccagt tgcggctcga
     3061 tacctcctcc tcgctcgagg tgcccctggt gcgcgcgggg acgaagcccg cgcgtgcgac
     3121 gccctcgcgt tcttccctcc cgcgctcgtc cctctcgcgc aaatcatcca tgggaaaccg
     3181 tgatgccgtc attgatccgt tcgctccttg agcgctccgg gtggtgggtg gccgtggtcg
     3241 tggggctgct cgccctcgcg cccctgtccg cgcgcgccca ggggggcgag gcgcgtgcgc
     3301 aggcccaggc ccgcgcgaag ttcctcgagg gcaatgccgc ctacgagcag gcgcagttcc
     3361 agaaggccct ggacgcctat gtcgaggcgt accggctgct gccgctgccc ggcttcctct
     3421 tcaacatcgc ccagtgctac cggcagttgg gtcagcccga gcaggccgcc accttctacc
     3481 gccgctacct ggcccaatcg aaacaaccgc cggccaatgc tccgctcgtg cgcgagttga
     3541 tcgccgagat ggacgcggcg gtgggcaagc cgcagcagaa ggactcctcc ctgcgcaagc
     3601 agacggcgga ggtggccgag cggcgcgcgc gtcaggacag cgagcgctcg cgcaccgtgg
     3661 cgtccaggtc cacgccggcg cagaccgagg tccagggcga gagtctggcg aagaagtggt
     3721 gggtgtgggc gggcgcgggc gccgtggcga tcgcggccgg cggcatcatc tacgccgcca
     3781 ccgcgcccca gccgcgtccc accaccctgg gcaccatccg ctagccacgc tcctctcggg
     3841 agccggggct caggccgggc tgttcggcga gccgcgcatc tgggccatca ccagcgcggc
     3901 cgcgtggccc atgcgctggt ggaagctctc ggcgtcgtgg aaggtgagcc gcacatcgcc
     3961 caactgcagg tgcatgccgc tctccagcgg ccgtggttgt ccgggcggca gcaactcgcc
     4021 gccgagcatc accggtccgc cctggctcag cgcttccacc gtccagcctc cgtccggccg
     4081 cgcgcgcagc agcaggtgct cgcgtgacac cgtcgcgtcg ttgatgacga aggcgttgtg
     4141 cgaggcccgg ccgatcatca gctcgtcgcg gcccggggtg agctcgaagc acatcgcgtc
     4201 gcccggcggc agacagtccc ggagatccga ggtcggcaac cgcgtcgcac cgtggttctg
     4261 ctcgctgctc tccggcacgt tccacacccc cgcctcccag accaaccaac tgtggggata
     4321 gcgggcgcgg aacttctcct tgagggccag gtgctggcgc acgagtaggg acatcaacag
     4381 ggatcgtgcc atggctccga gacaatcatc ttcacgcggg gatctccacc tcgacgcttc
     4441 ccgggaacgc ctggctgtcc aggagtgcgc ctttacgtgg cgtgaaatcc gggcgggtgt
     4501 cctcacgcga gcagcgtcac cttcacgatc tccggcggcg cggccacccg caccggagga
     4561 ccccagaagc ccgtgccccg gctcacgtag agcgagtgat cgccctcgcg gaacaagccg
     4621 gcgtcgtgct cccagatggc ggacaccgcc agggtgaagg ggaacatctg cccaccgtgc
     4681 gtgtgtccgg acaactgcag ccccatgccc gccttctgcg cttgatcgcg ccagcccgct
     4741 ggctgatgcg ccagcagcac cgacgcccgg gtgggatccc tccccgcgat ggccgccgac
     4801 aagtcgtagc cgcgctccgg gtagcccgag cgcgcggccg cccagtcatc cacgcccacc
     4861 agatcgaacg aggcgcccgc gtcgcccacg cgcacgtggc ggttgcgcag caccgtgacg
     4921 cccatgcgcg tgagggcctc ggtccactcc tcgtcgcccg agtagtactc gtgattgccc
     4981 gtgcagaagt acgtgccgaa gcgcgagcgc agctccccga gcgccgcggc cgcatggccc
     5041 aaccgctcca cgctgccgtc caccagatcg ccggtgatgc acaccaggtc gcccttcagg
     5101 gcgttggtgc gcgccaccag ctcgtccatg aagcggcgct ggatgagcgg gcccacgtgg
     5161 atgtcgctga gctgcacgat cgtgattcca tccagggcct tgggcagccc cggcagcttc
     5221 accgtcacct cgttcaccac cggggggtgg aaggcgcgcc acgtgccata ggtggtgatg
     5281 cctcccgtgg ccaccagcgc cacgcccgcg cccgcgcgcg cgaggaactc ccgccgctcc
     5341 tcggacacca gcgcggcgtt gcccgctgga gccgccgggg ccgggcgtcg gcgtccgatc
     5401 cacccggcca gggttcgtgc gccacccacc gccagcatcg tgagcagcag ataggcggcc
     5461 acgcccatcc agtaccaact accttgcgcg aaggcggacg cggccgccga gggcgcgagc
     5521 gccatgagcg gccgggacac gagcaggctc gcgccgagca cgcccatcag gaccacgccc
     5581 atgcgccgcc agtggggatg cctgcccgtg tcccggaaga gacgccggta caggtacagg
     5641 tgacctccca cgacggtgat ggacaggagg gcgaagaaga cgaggagccg cgtcggaatg
     5701 gccatgtgcc ctcgcatact cacgggcacc ctggatcgtc gcaacccttc cgttcatgaa
     5761 gaagcgtgaa gcgggcgcgc attcaaccaa gcagggagcg cagcgcctcg gacagctcgg
     5821 ggtggcggaa gacatagccc gtctcccggg cccgctcggg cagcacacgc tggccgccga
     5881 gcgccgtgac ggacatctcc cccagcgcga gcttcagcgc gaaggcgggc accggcacca
     5941 gggccggccg tcccagcgcc gcgcccaatg cctgggcgaa ccgcgcgttc gtcaccggct
     6001 cgggagccgt cacgttcatg ggccctcgca ggtcctcccg ctccagcgcg tggtgcagga
     6061 gccccacggc gtcctcgagg tgcacccagc tcaggtactg ccgccccgag cccatgcgcc
     6121 cccccacgcc cagccggaac aaggggagca tcgtctcgag cgcgccgccc gaggggtgca
     6181 gcaccacgcc gatgcgcgcc accaccgtgc ggatgcccgc gcgctcggcc tccagcgctt
     6241 cggtctccca gccctggcac acccgcgcga ggaagtcgcc tccgggtgct cccatctccg
     6301 tcaggggctc ctcgccacgg tccgccccgt agtagccaat ggccgaggcg gagacgaagc
     6361 cgcgcaccgt gcccgccgta cgcatcgcct ccaccagcag tcgcgtgccc accacccggc
     6421 tgtcctggat gcgctggcgc gcggcggccg tccagcgctg cgccacgggc tcgcccgcca
     6481 ggtgcaccac ggcctccgct cccgccaggg cctcgggcga caggggcgtg gtggcgtcga
     6541 agaaggagcc cgtcaccccc ggcggcagcc gcccgagcgc gcgcttcacg tcccgcgcca
     6601 gcacgtgcac cgcgtggccc gcgtccatca gcctctgcac caggggcggg cccaacagcc
     6661 cgctcgcgcc actgatggct accttcatgg ggcctccttc atggatgggc gtctcgcggc
     6721 gcgcctgtca tgtcccggcc gagcagcgtg cccaggtgcc cgaagaacac ctccatgtcc
     6781 tcttgatcca tgcggcccga gtagctgtag acgacccggc cgtccgcgct cagcagcatc
     6841 accgaggacg tcttcttcgg cagcttccag ggcgcatcgc ccaacacgcc cttcaggtcc
     6901 acgaggatgg gcacgcccca cttcttctcc tcgccgcgca cgtgcgacag cgcgatgtcc
     6961 cgcgcgggaa agaagttgaa ggactccagg ttggccaccg ccaccaccca cgccgcctgc
     7021 aacagcccca tctcccgtcc ccggttgaac agcgcgtcct tcaacgaggc gttgagtgtc
     7081 gtcgagtgac gatcctcata gaacagaatg acgggttttc cccgccaccg ggacaagtcc
     7141 acttcctttc catgtgaatc ccacaaggtt gcattcatcg ggactgcctc cagtggtgcg
     7201 gcgaggacgg agccggtggt caggaccgcg gccatcaggg ctcccgcgaa ccatctcttc
     7261 aggggggacg gtgctggaca gggcatgtac aaaccttgaa catagccttg acaaaccttg
     7321 aacgcaaagg ttacctgcac atccgaaggt agccacgcgt ctggaggagt gccgtatggg
     7381 gcccacgccg ttcatcgccg ctgcgcccag gttggctccc tccgtggagc ggacgtggtt
     7441 ggcgttggtg cgggcccagg tggagggcgt cctggacgag ctgttggtgc ttccggacga
     7501 ggcacggttg gacgaagggt gggcaagggc tcttggccag acgagggcgc agctgtcgcg
     7561 ctctccccag cagatgcgcc cggcgctgct gctggcgggc tactgcctcg cacgaggctc
     7621 cacggtggtg cccgcgggcc tgtggcgctt cgtcgcgggc ctcgaattgc tgcatgcctc
     7681 gcgggccctt cactccgatg tcctggcgtt ctcgcggccg cgtccggagg gagcgccgct
     7741 gcacgcgcgg ctcgcgccgg gacccgcggg gggacacctg gcggtggtcg tgggtgatca
     7801 cctcttcgcc cgcgcgctgg aagtgatgat ggaggcggac gtgccgggcg ccgtgcaggc
     7861 gagccagtac tgtctgcgga tggatcgctc cacggtgccg ggcctcttcc gccgggagca
     7921 gggcgggttg ctggcggagc agggtggcgt gcgtcaggca ttgaggctcg cccgcttgcg
     7981 gatggtgcgc gaggggctcg ccacctccct ggtgtgtggc gcgatgctgg cgggcgcgga
     8041 ggagtcactg cggctgcgcc tggcgggcgt ggggtgcggc ctggggctcg ccaccctgct
     8101 acgtcaggag tccgcgagcc tgctcgaggt gccttggggc ggccctggcg acttcgtgct
     8161 ggggcgatgc accttcccgt tgatggccgc ctggtcgcgc tcgcgacccg aggcgcgcgc
     8221 ggaactcgag gccctgtgga acctgccccg cgagcagaag gacgccgccg tgttgtcccg
     8281 ggtgcgcgtc ctggtggacg aggccggggg ccgctcggcc accgagcgga tcgccgcgcg
     8341 ggcggcgcac ggcgcggtgc gggcgctctc caccttgccc aatccccagg gcctgcgcga
     8401 cctgatgcga gcgctcgtgg gtccgtcgtc ccagccgatg gtttgagagg agatgcaccg
     8461 tggagcgtgg caagcgacaa gcggtggtgg tgggcgcggg cgtgggtggg ctcgcggcgg
     8521 cggcgcggct ggcccacgcg ggcttcagcg tgcacctgtt cgagaagacg gacggccccg
     8581 gcgggcgctg caatcagctc aaggtggacg ggttcacctg ggacctgggc cccaccatcg
     8641 tgctcatgcc cgaggtgttc gaggagacat tcaccgcgct cggccggcgc atggaggact
     8701 acctcacgct gcaccggtgc gatcccaact accgcatcca ctaccgtgac ggctcggcca
     8761 tcaccttcac ctccgagctg tgtgccatgg ggcgcgagct ggagcgggtg gagcccggca
     8821 gctaccagcg ctacctgtcc ttcctcgccc tcggccgcac ccagtaccgc acggggttgg
     8881 atcacctcgt gggccgcaac tacgagggcc tgtccgacta cttcgtgccc tcggtgttca
     8941 agcgcatcct cgaggtgcgt gcccaccggc gcatgtactc ggaggtcggc cgcttcttca
     9001 aggacgagcg gctgcgcgcg gggatgacct tccagtccat gtacctgggc gtgtctccct
     9061 atgccgcgcc gggcgtgttc gcgctgctgc ccttcaccga gctgggcgtg ggcgtctggt
     9121 ttccccaggg gggcctgtat gccattcccc tggcgctgga gaagctggcg cgcgaggagg
     9181 gcgtgcacct gcactacggc acgcccgtgc gacgcatcct caccgagggc aagcgcacca
     9241 cgggcgtgga gctggagggc ggcgaggtgg tacgggccga cgtcgtggtg tgtaacgcgg
     9301 atctgcccta cgcgtacgag aagctgctcg acaagaacgt cacgcggctc aagcgcgcgg
     9361 acaagctccg ctacacctcc agcggctaca tgctctacct gggcatgcgc cgacgctacg
     9421 acgaattcct ccaccacaac gtctacttcg gcaacgacta caagggctcg ttcgactcca
     9481 tcttcgagca cttccgcgtc cccgaggatc cgagcttcta cgtgaatgcc cccgcccaca
     9541 cggatccgag cctcgcgcca ccgggcaagg acgcgctcta catcctggtg cccgtgcccc
     9601 atcagcacga gggactggat tggaagacgg agggcccgcg cgtgcgcgcc aaggtgttcc
     9661 aacgactggc ggagctgggc cacacggagc tggagcgcga catcgaggtg gagcgcgtgc
     9721 tcaccccgga cgactgggcg tccacgttca acctggcgcg gggcagcgcc ttcgggctcg
     9781 cgcagaactt cttccagatt ggccccttcc gtccgtccaa tcaggatccg cgtgtgaaga
     9841 acctcttctt cgtgggagcc tccacgcagc ctggaacggg actgcccacg gtgctcatct
     9901 ccgcgcgtct ggcggtggag cgcatcctga cgtgggcggg agtggacaac gtggtgcgcg
     9961 cgcctggggg gaccgggccc ggttcaatgg aggaagcggc atgaagtcgc gggacgagaa
    10021 cctggttgcg aagggttacc ggatggcgga gcaggtgacc cggcaccatg ccaagagttt
    10081 cttcttcgct tcgttcatgt tgttcggcat gaggcgcaag gcggccttcg ccctctacgc
    10141 cttctgccga cggctggacg acatggtgga cgtggcggac ggggcggaca agggcgcggt
    10201 gcccacggac ctggccgagc ggctgacccg cgcgcggcgc gccgtggccg agctcttcct
    10261 ggacacgccc gaactggcgg acccccgcct gcctccgccc gccacgcgcg ccagcggggg
    10321 cgaggggccg tggcatcccg cggagctggc cgcgctcgtg gactgcatcc agcgcttccg
    10381 cgtgcccgag taccccatgc aggagctcat ctccggcatg gagatggacc tgacgatccg
    10441 ccgctacgac acctggtcgc agttggatct gtactgctac cgggtggccg gcgtggtggg
    10501 gctgatgatg gcggcgatgc tcgggtgctc cgaggagtgg gcgctcgggc ccgcggcgga
    10561 cctgggccgg ggcatgcagc tcaccaacat cctccgggac gtgggcgagg acctggagcg
    10621 cgaccgcgtc tatctgcccc tggaggagct ggcggccttc gggctgtcgc tggaggacct
    10681 gcgccggggc gtggtggatg accgctggcg cgacttcatg cgctggcaga tctcccgggc
    10741 gcgcgcctac tacgagcggg ccgcggcggg catccccgcg ctgtcgggct tcggctcgca
    10801 gcgcatggtg atgctcatgg gctccatcta cggagacatc ctgcgcgtca tcgaggagcg
    10861 cgacttcgac gtcttctcgg gccgctcggc cgtttccaag tcgcgcaagt tcgcgctggc
    10921 cacccacgcg ctcgtgcggc ccgcgacggt gcccctcatg cacgtgcgcg cgccgggagg
    10981 atcggtgccg ctgctgccgc ccgcgcgcgc cgtcacgacg ggatccatgc catgacgcgc
    11041 gagcgtccgg gagtcggaag atgaagtcca tgcgtgtcgc ggtggtgggt ggtggaatcg
    11101 gaggactgac ggccgccgga ctgctggcca gggagggtca tgacgtcacc ctcttcgagg
    11161 ggggtcccca cctcggtggc aaggcgcagt ccgtgcaggt gggcggactg cggctggaca
    11221 ccgggcccac gctgctcacg ctcccggacg tcgtgcgcgg tctgttcgat tcgctgggcg
    11281 cggcggacct gctgccgccc ttcctcgagc tggaggcgca gtgcacctac cacttcgcgg
    11341 acgggtgcgg cttcgtggcc tccaaggacc tcgagcgcac cgcgcacagc gccgcgcaac
    11401 tgcgtccgag cgaggggaaa ggcgtgcacg gcttctacgc ggaggccgag cacatctggc
    11461 gcgccgcggg cgagccctac ctggaggccc ccttcgaggg catggcgggc ttcatgtccc
    11521 gggtgctgcg tcggggcatg gtggccgtgg cccggggcat gaagctgtcc accctggacg
    11581 acctggcgcg ggcgcatttc aagacggagt acatgtggca attcgtgggt cgcttcgcca
    11641 cgtacgcggg ggcttcgccc tatgcggcga gcgcggccta tgccctggtg ccccacatcg
    11701 agcgcgcgta cggcgtgcac cacgtgcgag gtggaattgg cgcgctggtg gacgcgctcg
    11761 gggcggcggt ggctcgcctg ggcgtgaagg tgcacctgaa cacgcgcgtg cactaccagc
    11821 gcgagggcca cggctaccgg gtgggtccgt ccggcggcga ggagcgtttc gactcggtgg
    11881 tggtgaacgc ggacccgctg gacaagctgg gacgcgggag cgagccgctg tcgctgtcgg
    11941 gccatgtgct gctgctggag gtggatggcc gtcccgccct gccgcaccac gccgtgctct
    12001 tcagccggga ctaccggcgc gagttcgacg agctgttcgc gggccagctc gcggcggatc
    12061 ccaccgtgta cttctgcaac ccctcggcga cggacgacac ggtggcgccg ccggacaaga
    12121 cgggcctgtt cgtcatggtg aatgccccgg cgctgccgcg cgagcccggt gccgccgagc
    12181 gcgccgcggc ggagtgggag ctgcacggcg agcgggtgaa ggcgcagatg ttcgacaagc
    12241 tgctcaccca ctacccggag ctgaaggggc gcatgcgcgt ggtggcccag cgcacgccgg
    12301 tggacctggc cgcgttgggc gcgcccggag gttccatcta cggcttccta ccgcacggcc
    12361 gcttcggtcc cttccgccgt ccgcgcatcc ggggaggcac tcctggactc ttcttcgcgg
    12421 gaggaggcac gcatccgggc ggaggggttc ccctggtgat gctctcgggc cagttcgcgg
    12481 cccgcatggc gtccgcgcat ctgaggagcg gcgaatgagg cgcctggatt tgctgtcgcc
    12541 gcgcgccctc cggggcgagt cgtggctgga cgcgctgccg gcgctgccgg atacggccgg
    12601 ggcctatcgc tggttctacg ccgacgtgac ggcgggcgag tacagcgccg tcttcatctt
    12661 catgctcggc tcgctcttct cgccgcgcta ctcggtgggg gcgccgcggg gcgcgttgcc
    12721 gctgcaacac agcgcggtga acttcgcgct ctaccaccgt ggccgagggg tgcgctgggt
    12781 gctcagcgag tatccccagg cgttggtgtg ccagggaggc cgggagctgc tcatcggccg
    12841 ctcgcgcctg gagtacacgc gggatggccg ggtgtgcctg gaggtggacg agcagtgcgc
    12901 gccttttggc ggagcggtgc acgcgcggct ggagctccag cccgagtcct tctcgaccga
    12961 ggaggtgcaa ctggtgccgg gcgtgccgca ctactggcgg gcgctggcac ctcgggcgag
    13021 ggcgtggttg tcggtggact ccgaggacgt gcgcgccgag ggccacggct atcacgacac
    13081 caaccatggc gcggaactgc tgggcgcgcg gctgccgggc tggtactggg cacggctgca
    13141 cgggccggag gagacggtgg tggagtacca cctgccgggc ggagtggctc ccctgcgcgt
    13201 gacggcgagt gcccggggca cgtcgtgtga gcggtggccg gtgcgcgcgg agccgctggg
    13261 cacgcgcatg acgggatggg gcctgcgcgt gccggagcgg ctggtgtcga gccccggggg
    13321 ggcgaccgag ccccggttgc tggagtcctc tcccttctat gcccggctgg aggcacgcca
    13381 gggtggactg gacgtgatgg gggaggtggc ggacttccgg cgcttccact cgcccttcat
    13441 ccgctggatg gcgcacttcc gcacgcgcgt ggagcgccag acatgactac gtgggcggcc
    13501 ctggcaatgg cctggggagg actggccggg ggcttcagcg cggtggcgct ggcgcgcctc
    13561 atgcggcggc gtccggcggc tgcctccacg cgggtgccgg tgctgttgct gcgtccggtg
    13621 gatgcgccca cgccccgcga ggtggagaac ctggccacgc ccatcgacta cccgggtccg
    13681 ttggagcacg tggtgctcgc ccccgagcgg ccacccctgc ccgagcacgt gcggtgggtg
    13741 ccgagcgatc cctcgacgcc caaccgcaag gtggggcacc tgctgcatgc gctgagggtg
    13801 ctgccccggg agggccgggt ggtgctggtg gtggacgcgg acgtggtggt gacgggcgcg
    13861 ctggtggcgg gcctggcggc gccggtggcg gcgggcgcgg cgctgagcac ggcggtgccc
    13921 acgccggtgg acgcgcgggg actggccggg cgggccgtgg ccgcgctgct gcgccgcacg
    13981 caccacagct tccgggcgct gcacgtgatg agcgccgggg ccgcggcggt gtgtggcaag
    14041 gcgctcgggt tgagtggccg ggcggtggag gaactgccgg agctggcgga ccacatcggc
    14101 gaggacctgg agttgtccaa gcggctgcac gcgcgcggcc tcggcgtggc gttgtgcgag
    14161 gtgccggcgg tggtgcccct ggccgcggga gactgggacg cggccctggc ccgcttcacg
    14221 cgctggatgc aggtgttgcg cagccaccgg cccgggctct acccgacggt gcccctgctg
    14281 ttcacgccca cgtggccgct gctggtgctc ggcatggcgg cgggctcgtc gggcctgtgg
    14341 gggtgcgtgg cggcgctggt ggccgtgcgc accctgttgt cctggcggct cgcgcggctc
    14401 agcgctcccg gagcccaccc gggagcaggg agttccgagg gcggagcgta cagcttcgcg
    14461 ctggattggt tgttgggcga ggccctgttg ctcgccgcct tcgtccgctc cctcgcgcac
    14521 cccccgcggg tgacctggcg ggggcgcgtc tatgcgttgc acccaggagg ccggatgtca
    14581 cccggatgga cggaattgaa gcaggagggc ggggtatgac ctacgcacgt ttcctgggcc
    14641 tgttcgtcgt gctgcccatc gtcttgctgg cggtgcgcta ccggcgcgtg ctcaccgggc
    14701 gagccctgct gcccctggtg cccctgttgg ccatcgtcta cgtggccacg tgcccctggg
    14761 acaacctggc ggtgaagtgg gggctgtggc gcttcaagcc ggagctcatc tggggcatcg
    14821 tcgtgggcta cctgcccctg gaggagtacc tcttcttcgg cttgcagacg ctgctggtgg
    14881 gggtgtgggt gctcgcgcgg ctgcgtcggg tgtccctggc acccgccgcc cggaagtccc
    14941 ccgcgagccc cccggtgccc gcgggccagc accggctgga ctccaagctg ggctccaaca
    15001 agctgggctc caaggaggtg gtgtcatgat ggagtcgcgc tgggcgtacc tcatccatct
    15061 catggcgtgg gcgggcccct tcatcgcgct gcaactcggg gtgctggtgt tctacttccg
    15121 cgagcgctcc tggacggtgc tgcgcgcggc gctcgtgccg gcgggcgtca tgggcgtcta
    15181 cctgtcggtg gcggatcacc tggccatccg cgagggcatc tggagcttcg gggagggcaa
    15241 gcacctgggc atctacatcg gcgcggtgcc gctcgaggag ctgctcttct tcctgctcac
    15301 cagcgtcatg gtggcgctgg gcctgaccct cttcgccgcc ctgctggccc ggcgcgaggc
    15361 gcgcgtgccg tgatacacgc ggccaagggc gggtttccgg gatggatggt cgacacctat
    15421 gtgggctgga agttccgctc gtccttccgg ggcttgtggg tgcgcggagc gctggaggac
    15481 agcgtggccg ggcgcctcgt ctatgcgaac cactccaact ggtgggatgg cttcgtgctg
    15541 catcaacttg gccgggcggc gggttgggac acatactgcg tcatggagga gaagaacctg
    15601 gcgcgctatc gcttcctgtc gcgcatcggt gccttcagca tccggcgggg tgaggcggcc
    15661 tcgtccctgg agacactgcg ctacgcgagc tcgctgctcg cgcggccccg ggccgcggtg
    15721 tgtatcttcc cggagggtga gctgcggccc catggcgtgc gctcgctgaa gctggagcgc
    15781 ggggtggagc tgctcgcgcg ggtgagcggg gcgcgctgcg ttccgctctg catccgctac
    15841 gccttcttcg agcacgagcg gccggacgtg ctggtggagg tgggcgggtc gcacgcggcg
    15901 gctcccctgg agcgctaccg cgaggagctg gaggcggcgg cacggcggct ggaggcggcg
    15961 acgagtctgg agggcttcac ccaggtggtg tccggtgccc ggggcgtggc cgaacgttgg
    16021 gacgcggtgc gcggccatgg ctgagcgtac ctaccgcatt cacatcgccg ccgagttctc
    16081 cggcgtgaag gtggagctca tccgcgcctg ggagcggcgc tatggggtgc tctcgcccca
    16141 gcgcaccccc tcgggctacc gggtgtacac ggaccgggac gtggcgctgc tgcggcggct
    16201 caagcagctc accgaggagg gcgtgtccat cagcgaggcg gcgaagatgc tgccgcagct
    16261 cctggcggag atcgacgcgg cgcagccctc ccagtccccg cctccggagc cgagcgacgg
    16321 cagcgtggcc tcctggcgcg aggaggtgct ggaggccgtc agggtgttgg atcaacgtcg
    16381 ggtgtcggag acgctggacg aggtgctcgc ggcgctctct cccttgaagg cctacgagga
    16441 cgtgctggtg cccctgcagc aggaggtggg agagctgtgg caccagggcg tcttcacggt
    16501 ggggcaggag cacctggtga cgcaggagat ccgcgcgcgg ctcatcagcc tgctgtactc
    16561 cgcgcccaac aagggaccgc ggcacgcgct cctggcctgc ttcccggagg agcaacacga
    16621 gctgggcctc ttgggcatgg cgctgcggct gcggcactcc gggatgacgg tgacgctgct
    16681 gggccagcgc acgcccaccg acgaggtggt ccgcatagcg cgggcgctcg aggtggacct
    16741 cgtgggcctg tcggcggtgg tggaccccgg tgcccgggag ttcgaggaga tcctcacccg
    16801 ggtcacgcgc ggcctcactc cgggcatgga cgtctgggtg ggaggacggg cggcgctcca
    16861 gcaccgggcg ctgtgcgagc gcctgggcgt gcgtgtcttc gagcacgccg ccgactggcc
    16921 acggctcctg ggcggatagg ggagcgccgg gcgagggcgg ctcccggcgt gagcgcgctc
    16981 ctctatactc cgcgccggcc atgccactcg tgaaaagacc tgtcctgaag accccgagcg
    17041 ccgggatgct cctgggtgtc tgcttcctgt tcctctgcct cgcggtgccc ctgccggggt
    17101 gcgtgcacga ctccgggtcc gggcccgcca ggtcggacga ggcggtggcc ttcatcgggg
    17161 tgaatgtcgt ccccatggat tccgagcgcg tgctgccgga tcagacggtc atcgtccgcg
    17221 atgggctcat ctcggcgatg ggcccctcca cggccatcac cgtgccggcg ggcgcccggc
    17281 gcatcgaggc gaaggaccgc tatctgatgc ccggcctgtc ggacttccac atccacctgc
    17341 actcggacga gcagctcctg tcgtacctgg cccatggcgt caccaccgtc ttcgagctga
    17401 acggcacccc gcgccacctg aagctgcgcg agcagatcgc caggcgtcag gtgctcggcc
    17461 cccggctcta cacgagcagt ccgctcatgg atggaggccc cgaggggggc agcgtggtgt
    17521 cggtgaactc gcccgagcag gcgcgccagg cggtggtgcg ccagaagcgc gagggctatg
    17581 acgccatcaa ggtctacgac aacgtcccgc cgggggtgta cgagcagttg gtggccacgg
    17641 cgcgtgagca gaagctgccg gtgatggggc atgtgccgcg cagggtgggc gtggacgcgg
    17701 tgctgcgcgc gcgccaggcg ttcatctccc acggcatcga gtacttcctc gccggctcgc
    17761 gcgacgagtc acgcatccct ggcttcgcgc tcggcacgaa ggcggcgggg acgacggtgg
    17821 tgccggacct gtcgcacgtg cacacgtcct tgaagatgat ggaggacctg gagggcgtct
    17881 tctcggatcc cgaggcgcgc tacctgtccc cgaaggtgat gagcgactgg cgctactcca
    17941 acccgacgcg ccgggtggac gtgcggcagt tctccgagcg gcagcgggcg gcctacccct
    18001 tcgtgcagca cctcaccctg tcgctgcaga aggccggcgt gcggctggtg ctggggacga
    18061 acgcgtcgga cgcggggctc tttcccggca agacggtgca cctggagctg gcggagctgg
    18121 tgcgggcggg cctgtcgccc tacgaggccc tggtgacgag cacgcgcaac cccgcggcct
    18181 tcatcgagga gcacgtggac ccggcggcgc gcttcggcac ggtggcggtg ggccagcacg
    18241 cggatctgct gctcctgccg ggcaatcccc tggaggatgt cgggcaggcg gggcaggcgc
    18301 tcggggtgat ggtgcgtggc cagtggctga cgcgcgagca cctgcagcgc ctgcgcgaca
    18361 aggtggccga gtccttcaac cggtgagccc gggcggacgt ggggccccct ccgagagggg
    18421 gcctgctggc gccggggggc gtctccgact tcagcgtccg atcaggccgc gctcaactgg
    18481 cgctgcagcg actgggtgtc cacgttgctc cagtactcga cgatcttccc gttctcgagc
    18541 cggtagcgca ggttgtccac gacctccgcc gtgcggccgg tggccgggat gcccatgaag
    18601 gtgccgatgt gcttggcctt catgacgagc tgacacgaga aggtctctcc ctcctgggag
    18661 aagccgtcga cgcggaagct gatgtcggag aaggtgtcca ggaaggcgcg agtcatctgc
    18721 tcgaagccct ggatgccggg ggtctgcccc ggatagacgg ggtgggagac gatgttcgcg
    18781 gcgatgaagt cgcccagtcg ccccacattg cgctggatgt agagcgtgtt caggaaatcc
    18841 tcgtagaact gacgggcctt cgcggcgtcc atggtgggtc cttccggggt aatcggggaa
    18901 cgggatgata gcgggtgccg tgataaagac aacgactccc gccacgtgcg tctgcgattg
    18961 gtagggtggc ccattgccct gatggtgtgg agtgaattct tcagccgcgg tggatgtgcg
    19021 ctggacgcgt gtgtattcaa cctcacgggg cgtccagccc gggacgcgct cgcctgttcg
    19081 atttgcgtaa aagcaatagc acttcgagcc gggtcgtggg ggccaccaac tccaatggca
    19141 ctcccaacct gcggaaccag gtggagaagt ggggcctgga gctggcgtcg gaaggcctcg
    19201 tcgccctggc ggtcgacagc ttcacccggc gcaggccctc cacggtcccc gactcggaaa
    19261 tctccctgtg gcaggacccg tgctcgggca agaagtacgg agggcgggtc gatccctata
    19321 ccacccgcgt gctggatgcc caggcggctc gggcctggct ggcgacggac agccgtatca
    19381 acgcgacgcg cattggcatc ctgggcgggt tccagggcgc gcaggcggcc atggtggaga
    19441 ccgcgcgacc acggcctggt ccacctacgg ctccacgccg ggcagtgggc acgagttggt
    19501 gttcagctca tacacagacg ccgagcacgg cttcgatggc gagtcgcaga cctggcctac
    19561 gtccacgacg acctgctcga cgccggatac gtgcgccatg agggacgcgg acctcgactc
    19621 cctggccttc ttgctgtcac acctctagtt gaagccgaga cacgcctctt ggtattcgaa
    19681 ctgccccgcc tgctcaccct gctcgagtaa agctttgatg ttcgcgtagg gcacgtgggg
    19741 aggaacatcc accgccacca ggcggggcag gtcgctgagt tccgaggcac atccccgctg
    19801 gcggagggcc tcgcgcacgg actcgacatc ctcctggcgc gagaaccaga gctgaagggt
    19861 gctgtgtccg ctgggacgca ccagctcgga ataccagagg actccaccgg cgtctggttg
    19921 ggccgcgacc acgtccccga gtgagacttc cttcgcgtag aacgggatgt tatcgatttc
    19981 gtatccatcc tcccgcttga tgacccacag ggtctctgcc tcctcttctc cctccgcatt
    20041 ctcgaatggg aaacggagtt tcaggcgctc attcatggag acttgtcccc tttctcttga
    20101 ttgcactctc ggcagaggac ctgcccattg gaaggcgacc catcacctcc cttgcttttc
    20161 gggatgatgt ggtcacgctc gcgctgattg acgggtggcg acacgcctcg ctcgtttttc
    20221 ttcgcgggca cgacgtcctc cccgcagttc tcgcacttgt tgctgccgtt gttcttcgcg
    20281 gcgttcgccg catcgatctc cctcttcccc gcgggcgtga aggctttgcc tgagcgggct
    20341 cccccggaac tgcccctcat agccttaccg gccacgatgt tgagctggct tgaagaactc
    20401 ctgagcgccg actgcttttc gaccgccacg aatgtgagtg gggctacgag ggacgaggcc
    20461 ggttccggat ggatgcgggt atttgtggcc tggacagaga agggcacggc cagcgccagg
    20521 accgtagcgg cgaagaacaa gtggaccttc gggacgaggc tgcgaggcgt gaacatggtg
    20581 accttccaag aagaggtgct cggatcgagt tcaaaaaaaa ctttaccacc gtgacttcct
    20641 ggatgggacg gggagcgagc actccagacg aatccgtcct gcagccgtaa ggcgggagtg
    20701 gcgccgcgtg agtcacgccc atcccggtgg gctgtgtgtc cacaagttgt tggatgcatg
    20761 tccccgctgc ctgccccagt gatgtggctc ccctgcgctg accttcgacc agttcttgcg
    20821 catcgcgcac cacgcggttg cgcctgggtg tttccgccca ggaagtttag ctacactcgc
    20881 ggcgagttcg caggaggccc catgctcact atcgccctgc gcaaggccgg cgggcacatc
    20941 caggtactgg aagcaatcgc cttcaaggga cagcccgagg gcgatgcctt ctgccccagc
    21001 gaagactgcg ggcagccctt ggtgcccgtc tccgccttcg tgcgagtggg caatatcccc
    21061 gtgcgtgcct tttttcggca taggcggggc accgctgcga agcgcccgtg ttggggcgcg
    21121 aaaggggagg ggggcttgca cttcgccgcg aagctccatc tccgcgtgcg ccttcaggaa
    21181 ctctgcgaga agggtggagc gctggttgtg gaacaaccct gcctgcggtg tgcggtgggc
    21241 ctgagccacg aagtattgcg cacaaagccg agcgacgtgg tgcgcatcga gcactggttg
    21301 gacccgcgcc gcaccctgcg gccggacgtg gtgctcctcc gggcgggcgt tcctcttctc
    21361 tcctttgagg tgcgggcttc ccacccctgc tcgcccaaga aaattgccgc cctcactgtg
    21421 gctggggcac agatggtgga ggtggaggct tgggtgctgt tggggacgga gaccacgttg
    21481 acttggtacc cgtccgtgcc gcttccgctg aagcgggcgg tgctgccggt agcacggcag
    21541 ctatgccccg attgccagac ggcgcaggat ttcgaggccg cctgtgagcg ggcggcggag
    21601 gagcgtcgcc aacgcgagcg cgaggagcag cagcggtgcg acgcgcagcg tgcccgcgaa
    21661 agggaagagc aacagcggcg tgatgaactg tgcgctcgtg agcgccagac tgagtgggca
    21721 tgtgatgcgc agcgagccca tgagatggag gtgcagcgcg aggatgctcg tccggtgttg
    21781 cgtgtgcagg aggaggttgc gcgtgcgaag attgcagcga ccccgcgttt gggtactctg
    21841 ccgctcaatc ctcgtctcca tgcggcagct cctaatgtgg aagtgctcgc ccactgcttc
    21901 gtggacgtat gccgtccgga cggagtacgc gatgaactgg agcttgtctt ggagcgcgca
    21961 gtcggaggcc ccctgaaggc tcagttggtg gagcgtagag cgaaaaaccc caagcaagtg
    22021 caattgcatg cacagagtga tcgacggctg ttgatggagt ggtggggaac tgcggtgacg
    22081 gacacggatt ccctcctcca gaaggcgcgt gcagctgcct ccgccgagta caaggttgag
    22141 cgtgatgcgg gctgcatcgt ggatccccat gggggcttcc ggctcggtgc cgcggacgtg
    22201 agcgcgtggc ctcaccccaa ccactggtgg gaggagaggg cccagcggtg ggtccgggcg
    22261 cggctgcggc acatgctcgc ggacgagctg aaggtgtcgg agaacgccgt ggatgagagg
    22321 ctcccagcca ggtacttcca tcgcatactc gtgcggttca agcgcaacaa gcgggacttt
    22381 gcagcttacg aggcggtagg caatgccaca ttcgacgact ggctgcgtgg agggacatga
    22441 gtgcttctgt ctctgtcttg cctggaaagc caaaactctt atcaggtatg aagattgagt
    22501 ggacgtggat gtccgggctt gtgtggagta tcatgcctcg ccatggcgag agcttcatgc
    22561 ctggcgagga cgggcaactc attgttgttg ggggcgcagc tcattctggc ggggtgcacg
    22621 ggctggccgc gaggcgagcc agccggagag ttccactcca gccctgatgc gtgtcaaatg
    22681 cctcatcacg acgcgaggga ccagcgctcg ctgccatgtc ctccaaaccg ttccggaagt
    22741 cgaggccagg atcgtgacgg cgctgtccat gcatcagcgt gaggccatcc ttcatcgggg
    22801 aaggcctgcc tggattgact ataccttcaa catccaggtc cagccgtcgg atttcaacgc
    22861 catccccaag agtctgtatg ccacatgggc gaagaagacg tccggggaaa cagaggcaca
    22921 gacgacggac gcggagttgc tccagctggc ctcctttctg tgtcggcatc aaccgctcga
    22981 tttccccgcg acttcgcggc ttcccgctgg agtggatccc tccctgctca tccgtcggga
    23041 ggatcttctc ttcaacgttg ggccgagttg caccccgccc gcagtgagcc gtccgtccat
    23101 tccctctcgt tcgtgaaatc gcccgaaggc tggttcgccg actaccagct tccggagaag
    23161 gcgcacccgg ccgctccgta gtcggacatg cgcctcagtt caccccgccc atcatccgcc
    23221 gcaagggttt gacgaagagg gcgagcagga ggcccgcggc gatggcgacg gcggccaccg
    23281 cgccgaagag ctggggcagg ggcatggcct cgaactgccc ggccacgcgc ccggcgatga
    23341 ggttgccgag cgacatggac atgaaccaca cgcccatcat catgcccacc gtgcgtggcg
    23401 gagcgagctt cgtcaccgtg ctcaatccca cggggctcag gctcagctcg ccgaaggtgt
    23461 gcagcaggta ggtgagcacc agccacatcg ggctcacccg atggcctccc gcggccgcga
    23521 gcgacgcgcc caccatcacc aggaatcccg cccccaacat caccagtccc agggagaact
    23581 tggcgggact ggagggctcg tggcctcgcc ggttgagcca cacccacagc caggcgaaca
    23641 ccggcgccag ggtgatgatg aataccccat tgatggactg gaggaggctc gcgggcacgt
    23701 tccagccgaa cacgtcgcgg tccgtgagct cccgggcgaa gaggttgagc gaggagcccg
    23761 cctgctcgaa gccggcccag aagacggtgg agctcaggaa gaagacaccg atgaccgcca
    23821 ggcggcgctt gtccgcggcc tcgagccccc ccgcggcgaa catgtacccg aagaaggcga
    23881 gcgcgagcgc cacgatgacg aagcccgccg cgtcgcccag gcccaccgcg ttcgtcatgt
    23941 ccacgacgcc caatccctgc aacacgccca ggagcaccac cagcaccgcc cccactccga
    24001 gcaccagacc gcgcgagccc gcgcgtggcg cctcggcgga cggctccgtg ctcccgcgcg
    24061 tggacagtcc cacgtcgccc aggtgtctgg cgcccgccac gtactggatg agcccgagca
    24121 ccatgccgac gcccgcgacg ccaaagcccg cgtgccagct cacgcgctcg cccagcaggc
    24181 ccaccacgat gggcgccacg gacacgccga tgttgatgcc catgtagaag atggagaagc
    24241 ccgcgtcgcg ccgcgccccg ccctcggggt agagcccacc caccatggcg ctgatgttgg
    24301 gcttgagcag ccccgtgccc gtcacgatga gcacgagccc caggtagaag aacgccaccc
    24361 cggtcatcgc catgctgaag tgcccgagcg cgatgatgat gccgcccacg agcaccgcgc
    24421 gccgctggcc gatgaaccgg tccgcgagcc agcctcccgg cagcgcggtg aggtacaccg
    24481 ccgagccata caggccatag atggcgctcg ccttcgccgt gtcgaagccc agtcctcccc
    24541 gcgccgccgt ctccgtcatg aagaggatga gcaacgcctt catgccgtag aagctgaagc
    24601 gctcccacat ctccgtgaag aacagcgtgg ccagtccccg cggatggccg aagaagcccc
    24661 gggtcgcgag cggtggggcc gccgattctc cggagagcga gggggccgtg gtcatcgtca
    24721 tggcgaactc caagggggaa cggctggcgt acgtcctgcc gacccctcac tctatcgctt
    24781 ggacttttcc agggccattg gatgcactcg cgttcgcgcg cggaggctca cgaaccttcg
    24841 gaggcgcgag cgttcacgct agagtcgccc cgcccacggg ccagaagaac ctggtgcgtg
    24901 gtccccttcg acgagacgag acacggagat gcctgtcccc cagaacgtgg ccacggacta
    24961 tggtttccgc tcgaccgccc ccgggtacat cattcccgcg gaagcgcgtc tgtggttcga
    25021 ggatctcaag gcccgggtgc ttcgcctcga gggacggccc ttcgggttgc tggtggattc
    25081 acgcacccag aagtccaatc cccccgagag ccaggagatc atccgcgatg cgatggtgtg
    25141 gttgcgcgac catggcatgc agcgctcggt ggtggtgttg gacagcaccg tggcgttgat
    25201 ccagatcctc cgcatcgcca agtccacggg cgtctactcc tacgagcgct acctggatgc
    25261 gttgaaggag ccgcagtggg agcgcaaggc ggtggattgg ctcgcccacg gcatcgaccc
    25321 ggacctgccg cccccttccc cctcgcggga gggttgaggt tgcggcccat gtc
//
