LOCUS       NZ_CP022098            21062 bp    DNA     circular CON 17-FEB-2024
DEFINITION  Cystobacter fuscus strain DSM 52655 chromosome, complete genome.
ACCESSION   NZ_CP022098
VERSION     NZ_CP022098.1
KEYWORDS    RefSeq.
SOURCE      Cystobacter fuscus
  ORGANISM  Cystobacter fuscus
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Cystobacter.
REFERENCE   1  (bases 1 to 12349744)
  AUTHORS   Rupp,O., Goesmann,A. and Sogaard-Andersen,L.
  TITLE     Sequencing and comparative analysis of myxobacterial genomes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12349744)
  AUTHORS   Bruckskotten,M., Treuner-Lange,A., Rupp,O., Goesmann,A. and
            Sogaard-Andersen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2017) Department of Ecophysiology, Max Planck
            Institute for Terrestrial Microbiology, Karl von Frisch Str. 10,
            Marburg, Hessen 35043, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 09-AUG-2016
            Assembly Method                   :: Celera Assembler v. 8.1
            Expected Final Version            :: yes
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/17/2024 10:04:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,093
            CDSs (total)                      :: 10,016
            Genes (coding)                    :: 9,906
            CDSs (with protein)               :: 9,906
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 26 of 110
            Pseudo Genes (incomplete)         :: 101 of 110
            Pseudo Genes (internal stop)      :: 1 of 110
            Pseudo Genes (multiple problems)  :: 17 of 110
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:24:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1078125
            Orig. end                         :: 1099187
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21062
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="5"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21062
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21062
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11062](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11062
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(1003..1989)
                     /locus_tag="CYFUS_RS04515"
                     /old_locus_tag="CYFUS_000902"
     CDS             complement(1003..1989)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002625957.1"
                     /locus_tag="CYFUS_RS04515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000902"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_095984107.1"
                     /transl_table=11
                     /translation="MTDSLRIVSYNVRYFGHALRGLASTLGPKRRVAAALATLEPLPDI
                     ICLQEVETQSFRSSVAHRPARPDETQLEAFMGRMEETFALLNRPMPYEAFYFRAHRYGV
                     RDFSLYTTGLAILVNTRRLAVDTHNVDAPHPITHHHVQMLRERKQSRICAHMRLVRQED
                     GLPLHVFNTHLSLPTPFARAFWATRDKMGNGINQLHEARALAALVQRHSRGEPFVVCGD
                     FNSPPASPVYQFFCDEARFTSAQAAVGQIDPRVSRGFPTAGFMHMRMHLDHIFSGEHVR
                     WLDTDSTHAFGDTRSRFHGLSDHMPLIARFLLESPTARAEASTPPAP"
     gene            2172..3014
                     /locus_tag="CYFUS_RS04520"
                     /old_locus_tag="CYFUS_000903"
     CDS             2172..3014
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002613243.1"
                     /locus_tag="CYFUS_RS04520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000903"
                     /product="MoxR family ATPase"
                     /protein_id="WP_095984108.1"
                     /transl_table=11
                     /translation="MTPPPSRFHGTDTYLSSEGLQAAVNCALTLQRPLLVRGEPGTGKT
                     LLAEAVAQSLGLRLLTWHVKSTTRAQDGLYVYDTVQRLYDSRFGDGDVRDIRRYIRLGP
                     LGEAFASKERVVLLLDEVDKADVEFPNDLLHELDRMRFRVTETNEDVVATHRPVVIITS
                     NNEKELPDAFLRRCVFHFIDFPDQELMRRIVEVHHPNLDASLTEQSLKVFYELRNFTRL
                     RKRPSTSELVDWIAVLKANGVTQVKLDEQLPFLGALIKREQDLMAVADAFGRGRRTKA"
     gene            3026..4228
                     /locus_tag="CYFUS_RS04525"
                     /old_locus_tag="CYFUS_000904"
     CDS             3026..4228
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002625955.1"
                     /locus_tag="CYFUS_RS04525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000904"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_095984109.1"
                     /transl_table=11
                     /translation="MFLPFLYELRRRGVPVGAHEAISLAGALKAGLHDSSLDGFYHVAR
                     ALLVHAETHLDAFDQAFLAHFKGVEVAGQQLTEELLEWLKEARERHELTPEERALLEHF
                     DAEELEKLFQQRLEEQRERHDGGTKWIGTGGASPFGHSGQPREGFRVGGPAASGSKQAM
                     RLAGARAYQGYRGDVVLDTRQMAVALRKLRAFTREGAPDELDVEGSIAATAKNAGELEV
                     VTRPPRKPNTRVVLMMDVGGSMDPYAHLVSRLFSVAKQATHFKELRTYYFHNCVYGRVF
                     ENATLTGGISVPDLMGQVGRHYKLVMVGDALMAPYELTLRTDVYGRYALEGGKEGLVWL
                     MELARHFERSAWLNPEPIQTWRGNTIAAVRNVFDMFPLTLDGLGEAVGHLTKGKMVRGR
                     K"
     gene            complement(4251..4721)
                     /locus_tag="CYFUS_RS04530"
                     /old_locus_tag="CYFUS_000905"
     CDS             complement(4251..4721)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002626364.1"
                     /locus_tag="CYFUS_RS04530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000905"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_095984110.1"
                     /transl_table=11
                     /translation="MTEGSAWQGPWKVRLCERVRERGFDSLTAFAEARPAVPLHVLAEE
                     LGEEDVAGVQVLSGLLAEAEQRKQVTRFVRDVLVRLLSQSVPDGWPAVMDDANRFKVAE
                     ALGSWSAYTPETHEERVARARATLRATPPPPGWRPLNPDDELLRTLLPDEEA"
     gene            complement(4818..5465)
                     /locus_tag="CYFUS_RS04535"
                     /old_locus_tag="CYFUS_000906"
     CDS             complement(4818..5465)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS04535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_000906"
                     /product="hypothetical protein"
                     /protein_id="WP_095984111.1"
                     /transl_table=11
                     /translation="MRKLVSIAALVLPLACRDWPEPVIRSVSPSEMRASEATALALDTE
                     LVLPATVDYDKGTVKVDTQVSVRIGALEVPTLAISPEGVISTRVPSMLPPGSYDVKVTL
                     GDGRTTERPGGLTVVEGEWPEGYSIDPIGPQKRLEPFTLTVRATGANAAAFRGNVRLET
                     GAGGTIGPRVSEPFVDGVLTQQVVVNSIQSDVVILVTDIAGHKGESNTFVLQ"
     gene            complement(5462..6148)
                     /locus_tag="CYFUS_RS04540"
                     /old_locus_tag="CYFUS_000907"
     CDS             complement(5462..6148)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS04540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_000907"
                     /product="hypothetical protein"
                     /protein_id="WP_095984112.1"
                     /transl_table=11
                     /translation="MRWLALLFLLSSTAAVAAPEGSSRGTSPKKPKAPARETSPKPSPT
                     APSRTGTRPAATQSAEQTRYALALAGGGFYGGGFNRGPQGSAQLTLTPPGWGRFSIDVE
                     LGWRLARFREDIPGTGVAVSALHSLPLLAVGRMNLVRMAHLGVDVRVGVGPLLALHHLS
                     SDFSASSVRSAIGWELLAGAQLRFPLGAIEPFLDARVGFGEAYIPFVIGRSTGVQGLLG
                     VRYQLP"
     gene            complement(6376..6846)
                     /locus_tag="CYFUS_RS04545"
                     /old_locus_tag="CYFUS_000908"
     CDS             complement(6376..6846)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002625954.1"
                     /locus_tag="CYFUS_RS04545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000908"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_095984113.1"
                     /transl_table=11
                     /translation="MTKGSAWQGNWRVRLYERIRERGFDSLTAFADARPAVPLHALAEE
                     LGEEDVAGVQVMGGLLAEAEQRKQVTRFVRDVLVRILSQNLPEGWPAILDESSRFTVAQ
                     SFAMWTSFTPETHKERVMQARAALRATPPPPGWRPLSPDDELLRTLLPDEEV"
     misc_feature    complement(6667..6669)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7029..8015)
                     /locus_tag="CYFUS_RS04550"
                     /old_locus_tag="CYFUS_000909"
     CDS             complement(7029..8015)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002625949.1"
                     /locus_tag="CYFUS_RS04550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000909"
                     /product="type VI immunity family protein"
                     /protein_id="WP_095984114.1"
                     /transl_table=11
                     /translation="MSHRLPRIRHYAATPGGEVLVQRDVVRLVLHLPFDHVDLSAGVNR
                     ALDMYLSSVGQGPEILSEWCDVEGEDDLFPLDAQGWDFIRSELSPPRGERFLDDVRDDE
                     RYVLRRVKKQFDRSVELSGGEGGLSGYGFFYWGRLPWRTPQADEVSLVSFSWPTEYMEA
                     RGSGKMRAEIEQLAALLPYASGHAGLAFYSSSVWGPVMKDIHEEALRYPGLDVTHGQRA
                     LGARVDGVHWLNFLGPEVLVQVGGAEALRSRLHAPTTTVTALEEERALVVLSPEPEAGD
                     VSQGNTLPAWRELARVLEPWLLPFPHYLSWRDCPPDTARRWWRRFLD"
     misc_feature    complement(7152..7154)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8613..9986
                     /locus_tag="CYFUS_RS04555"
                     /old_locus_tag="CYFUS_000910"
     CDS             8613..9986
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002623481.1"
                     /locus_tag="CYFUS_RS04555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000910"
                     /product="cytochrome P450"
                     /protein_id="WP_095984115.1"
                     /sec_met_domain="p450 (E-value: 1.6e-88, bitscore: 296.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTAVTSSPPASVREAPGGLPLLGHALRLVRSPLDYLQSLSGLGD
                     IVQLRVGPSPLYVVTSPECIHQVLVTQAESFERGRIFDKATVAIGKGLIVSNGAFHRRQ
                     RKLLQPGFHRPRIHGYMETIHRQVGAQIAGWSPGAHLSLREEMHRLTLNSVTRTLFGAN
                     TEERITAEIGDYIDAANSWVGLHTLLSGRFFERLPMPINRAFVRKKARFNEILDEFIES
                     RRADGRDQGDLLSALLASQDDETGQGMSDEQLRMEISGLFVAGSETTATALTWLFYEVG
                     RHPEVEARLHAEVDAVLGGRAITPDDLPRLQYLQNVISETLRRHSPIWVFTRRTTRALE
                     LAGTHLPAGAEVIISPMMVHRNPHLYSEPLRFDPDRWLPERMQEIPRHAFIPFGDGKHK
                     CIGDYFARTEMVIAVATIAARWRLVPVPGHRVREVPRAVLRPNQVLMTAVPRSSTPVS"
     gene            10001..11062
                     /locus_tag="CYFUS_RS04560"
                     /old_locus_tag="CYFUS_000911"
     CDS             10001..11062
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002623482.1"
                     /locus_tag="CYFUS_RS04560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000911"
                     /product="terpene synthase"
                     /protein_id="WP_232537368.1"
                     /sec_met_domain="T1TS (E-value: 1.8e-56, bitscore: 191.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTQRAAIEFRFPFPRDLSPDIEQAQRHSVEWARQMGLATTDFAL
                     GQLEAWNWGRLTGHCLPTGRGDILDLATEWITWGFLYDDQFAGPLGNQPERVARITENM
                     IGVLYSTSGTPGENAAARGIADILQRLTPKMSATWMARFRDHLKWYLIGVLRMTTFRNR
                     LGEIDTRTAFELRRLDIGMNAMIDFIEVAEGFEVPASVIGASQLQALRQCVVDIVLLQN
                     DVFSLPKDRHQQEVNVVLAMERAEKLTTAQALERTAALVDETVQRFLTVKAGMPVLYDT
                     LGLGATDRARLDRYIHCLELMAHGSVYSHAECVRYSTRPEHTRPIAGRGFIQDLHLDAG
                     IELAHELTRTNRG"
     gene            complement(11088..11900)
                     /locus_tag="CYFUS_RS04565"
                     /old_locus_tag="CYFUS_000912"
     CDS             complement(11088..11900)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033381.1"
                     /locus_tag="CYFUS_RS04565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000912"
                     /product="monalysin family beta-barrel pore-forming toxin"
                     /protein_id="WP_157758236.1"
                     /transl_table=11
                     /translation="MSHEKPVSVTQQDSGFLELRNVSDFLRHQKSAVTAPNIVTGQLNS
                     TSYPWAVGGDVGIDSCLENQDPPPGCWVDGETVYGDIYIKTQSWGTYTRPIFAYLKYVN
                     TYTYPSGATHHYATTQTVGLTETFTKEVNASYSVGANIDIVNTSSSIETGFSKSSSWSQ
                     QTIQSWTATLQGPATFYIYQVALVYAHCATKAGKSCASSFKYQRTRVINESRTDLYYLS
                     SISKKDMVILSKPLIPLSWDQVQQYVLIDNWNTWYFDYSAHGDPFRRY"
     gene            12127..12615
                     /locus_tag="CYFUS_RS04570"
                     /old_locus_tag="CYFUS_000913"
     CDS             12127..12615
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002625944.1"
                     /locus_tag="CYFUS_RS04570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000913"
                     /product="hypothetical protein"
                     /protein_id="WP_232537369.1"
                     /transl_table=11
                     /translation="MSPDAPSAPGLLAVDLGLRSGLALYGQDGRLRWYRSQNFGSPSRL
                     KRAVPAVLHSAGPLAWLVLEGGGPIAEVWEREALRRALPVLRVSAQDWRARLLYAREQR
                     SGGVAKDAAGVLARRVIDWSDAPRPTSLRHDAAEAVLLGLWGALEVGWLAQVPPEVRR"
     gene            complement(12632..13243)
                     /locus_tag="CYFUS_RS04575"
                     /old_locus_tag="CYFUS_000914"
     CDS             complement(12632..13243)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002625943.1"
                     /locus_tag="CYFUS_RS04575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000914"
                     /product="YdeI/OmpD-associated family protein"
                     /protein_id="WP_095984118.1"
                     /transl_table=11
                     /translation="MKPPSKPPSKPTFFATPADWRAWLEKHHDQQPELLVGFYKRDSGR
                     PSITWPESVDQALCFGWIDGVRKRHDEHSYTIRFTPRKPRSIWSSVNIQRVQELIEQEL
                     MRPAGLRAFEARSAERSGIYSHEQEDIALPEAYDKQLKANKKAWSFFQAQAPWYQRSAL
                     HWITSAKKEETRLKRLATLLQDSAEGRTVQPFTRTTKTSK"
     gene            13294..14220
                     /locus_tag="CYFUS_RS04580"
                     /old_locus_tag="CYFUS_000915"
     CDS             13294..14220
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS04580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_000915"
                     /product="hypothetical protein"
                     /protein_id="WP_095984119.1"
                     /transl_table=11
                     /translation="MRSFLLFPILLLGTSVSAAEPASTLRFAWPKGLKARVEVHIQGER
                     EAGDRTQRHDARATFTLSTQLQGEELQVKREDFSGWKGTLPARMGSPTDRLVDRIPLVR
                     VSRQGEFLGIEGAAKAREAFASEVKLESLDTANRRVFGMVTTDEALRAVALDFWNMSAG
                     AWPRLNLGPGKSRELRSPTAVPQLGGGKLDLVTTFRWVGPAACTPDEKEPRCVELVLKS
                     NPDSEQAKKLLQQALTAQSGNGPVTESFESTQELRAVVEPATLVPHRLTLRRSSQMRLR
                     SPQGKSESGREQTERAYVFHYTSPAAP"
     gene            complement(14233..15396)
                     /locus_tag="CYFUS_RS04585"
                     /old_locus_tag="CYFUS_000916"
     CDS             complement(14233..15396)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014395905.1"
                     /locus_tag="CYFUS_RS04585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000916"
                     /product="DUF6068 family protein"
                     /protein_id="WP_332468338.1"
                     /transl_table=11
                     /translation="MRMRFPFRSSVPLGMALVLLAGCQGMKSGGLAPTPPEPPIPSATS
                     PWQRARVGDAVTYTFSAWQGAAPGGTARSLRGLVTLEVVAVQQPWVWVDVSFTDEAGKP
                     LAPVWLAWPQLLPVRSDVTRPIEVPPLGKPAAERPTVAGRAWDAQRFEKDSRPVDGPLV
                     SRVYATEPGPLYLTRGLLSARTETAGFHVPGGSEWTLRDFREGSSTASPAAPALERPLG
                     SGTYYDRRLEQGPTPTLTRVCFGAERGYLLRTEAPLDTQAAPCTNFAEAEPEPLEEVLT
                     GLVWEAVAVPWPPATAAAGTRGTFEAEGHAVPALTAQRTENDGSTQRVLSETYAADPWS
                     PTLAGLAREARFQPLAESTERVEKGGKREFEGGSRLVRWGSWLSGAK"
     gene            15454..17445
                     /locus_tag="CYFUS_RS04590"
                     /old_locus_tag="CYFUS_000917"
     CDS             15454..17445
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002625940.1"
                     /locus_tag="CYFUS_RS04590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000917"
                     /product="hypothetical protein"
                     /protein_id="WP_095984120.1"
                     /transl_table=11
                     /translation="MSPSLPVRRVVLYKHGVGYFERRGTVEGRETLHLDFKARDMNDVL
                     KSMTVLDLSGGSVSAVSYDSTQPLEQRLQDITLRIPESGSLTSLLGQVKGARVRARVGT
                     EQLVEGVIVGLDSMSVAEGDTVVERPYLTLLVGAALRGFDLLEVAELTFLDDAVRADLE
                     FYLATMLSSYKKDSKRVSVLTAGEGKRELFVSYVLEAPVWKTSYRILLEEGKPPVLQGW
                     AVVDNTGDEDWEQVELTLMAGLPVSFVHDLYNPRYLRRPVVEVRTEAAVAPVIPEEGFG
                     AVREMAAEPEAAVAPMAASAPALAPAPMMRAMSSGGMARREAQERSAAVQTVTKEVGEL
                     FEYRVQHPVTVRRNQSALVPILHRPFEGRRVLLYNRATREKNPLACLELRNTTGLTLEG
                     GPVTVTEGDTYVGEAMLDTMKPEDRRLVPYAVELGFVVSVEDRSEEGPVRRAMVSHGVL
                     TVEFMMMRRTHYHLRNKAKRAQILFLEHPRTEGWRLDQVGAPDETTDHYWRFTRGLAAG
                     GSETFTVTESSGRQRTYLLANTGLDEVSFFLSSGFIDERVARSLREIISLRERVARRSE
                     EVRQRTEERAQLFKDQERIRANIESLKSGTPQRELVARFVTKLNEQEDRLEGIARELER
                     LAQEQREAQEEVNRQIQRLAFSTEPVKP"
     misc_feature    15493..15513
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.4"
                     /tool="antismash"
     gene            complement(17452..19173)
                     /locus_tag="CYFUS_RS04595"
                     /old_locus_tag="CYFUS_000918"
     CDS             complement(17452..19173)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS04595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_000918"
                     /product="hypothetical protein"
                     /protein_id="WP_095984121.1"
                     /transl_table=11
                     /translation="MRWGRQLRCGIARHSPLLVALLSLGLWDSPPRASTRMETEPLLPR
                     GLTLELPPPQTVNEEEVLRITLPVKGGRPGTRVFVEGLPPGALWHEPSRTLTFQPDFIQ
                     GGWRHEVTFTAVDGEQRVQGELMVTVRDTVRPPEPRIVQREEEAGSLRLTLEQPTDTWL
                     DSPSQAGRTFPAVVTVPLAATARQPMPVTVRLHGVGNWPPSPEVSRDRFIIQPSDPQLT
                     YWYGYSEDVLRGTAPRGSVPPYTVRRVLALLEWVLRSYPSADPNRVFVEGDSMGGAGAL
                     TLGLLDARHFAGVVARHAQPVARAHRPWRVAQLSSLWGMPEEEVPGPAGLGVWSRLDMT
                     RALRDEPEARSQFLILEHGKDDPIIHFGSMVSPSTLTGSSFYETLQTQHIGHVAVWHEG
                     GHTEPDPWLGERWWDRGWNPRTDPKSFLRRDVAFPAFSRSSWDGDPGRGGNGHQPWSKE
                     SGYAGDPKVAGDTGWDGDVAGMFNRALRWDASRLVDTPQRFVMPLRAVLGPGVTTIPQV
                     DVTPRRVQRFQCLPGERIRWSFGHSHGTVFAAPDGGVTVPRLSLRGDWTPLVLERG"
     misc_feature    complement(19242..19255)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.22"
                     /tool="antismash"
     gene            complement(19317..20090)
                     /locus_tag="CYFUS_RS04600"
                     /old_locus_tag="CYFUS_000919"
     CDS             complement(19317..20090)
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011550792.1"
                     /locus_tag="CYFUS_RS04600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000919"
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="WP_095984122.1"
                     /transl_table=11
                     /translation="MIPLSDDNPTLRSPVITYLFLGAIGATWVLVQGAGLNPLVLATSV
                     CNLGLVPGELTGLAPEGFPVQIGEGLACVVDREPINTLTPLTSMFLHGSWSHLLGNCLF
                     FWVFGNNVEDSMGRLRFIVFYIVCGLAAAAAQVLVDPASPIPMVGASGAISGVMGAYLL
                     LYPSVRVNMLFIFIIFFKVIPLPAWMVLLYWFGLQVITGLPQLNSLSAEGGSGVAVWAH
                     VGGFVAGLVLIKFFENPRLTRQRSGWRHRLHPDHP"
     misc_feature    20068..20088
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.77"
                     /tool="antismash"
ORIGIN
        1 accggctcct gccgctccag ccggcgctcc aggcccgcca gccgcagcga caggggggtg
       61 aggggcgtct tgagctcgtg cgaggcgatg gtgaggaagt cgtcgcgcac gcggatggcc
      121 tcctgggcct cgcgcagcag gcgggtgcgc tcgctctccg cgtggcgctg ctcggtgatg
      181 tcctcgacga tgcccacgcc gccctccacc tcgccatgct ccccgatgca cggggccagg
      241 tggacgcgca cgggtgtcac cttgtccgtg ggggtggagt ggtagtcccc ctcgtaatag
      301 gcatggcgcc cgtcgagcac gtcgcgcacg cagtccgcca gggacttgtc cgggagcgac
      361 agcaggcgca gcccgatgat gcggggccgg gccgcgccga tgatgcgcgc gagatagtca
      421 ttgcacgcca ggagggtgga ggtcgcgtcg aagtggaaca ggcccagggg ggcgttgtcg
      481 aagacgagct ggtgggcacg ctccccggac gtgacctcgg cggggcgccg cacgagcacg
      541 ctgatatatt cctcgcgctc ctggccggag cacccgaccg tcacgtcgac ctcctgccgc
      601 gacccgtcgc cgcgcaggag gacggtccgc acggcctgcc cgctccggtt cctggcgagc
      661 agggaacgaa ggaaggagcg ctcgccggac gtctccgggt gcgcggagag caggcgcgag
      721 aagggctgcc ccacgagctg ccccgtgctc caacccagca ggcgttcggc ggcgggattc
      781 aggtagcgca cgcgctcgcc cgcgtcgcag gccacgagcg gttctgtcag cgcatccatc
      841 catcgccgtg cgtcatctcc agacatgcct cctcccgaaa gagcgtcccc ctttgatggg
      901 tagggtggcg atggcccgtc tgtgccgtga gccctcccag gcgaatccac ggcgcatcgt
      961 gaccccgccc gggcggcgag cgagcggacg tgggagggga cttcacggcg cggggggagt
     1021 ggacgcctcg gcccgtgcgg tcggggactc cagcaggaag cgcgcgatga ggggcatgtg
     1081 gtccgacagc ccatggaagc ggctgcgcgt gtcgccaaag gcgtgcgtgc tgtcggtgtc
     1141 gagccaccgc acgtgctcgc cggagaagat gtggtccagg tgcatgcgca tgtgcatgaa
     1201 gcccgcggtg gggaagcccc gggagacgcg cggatcgatc tgccccaccg ccgcctgggc
     1261 actggtgaag cgcgcctcgt cacagaagaa ctggtagacg ggcgaggccg ggggcgagtt
     1321 gaagtccccg caaacgacga agggctcgcc ccgtgagtgg cgctgcacga gcgcggcgag
     1381 ggcacgtgcc tcgtggagct ggttgatgcc gttgcccatc ttgtcccggg tggcccagaa
     1441 ggcgcgggcg aagggcgtgg gcaggctcag gtgggtgttg aagacatgca ggggcagccc
     1501 atcctcctgg cgcaccaggc gcatgtgggc gcagatgcgg ctctgcttgc gctcgcgcag
     1561 catctgcacg tggtggtggg tgatggggtg gggcgcgtcc acgttgtggg tgtccaccgc
     1621 gagccgccgg gtgttgacga ggatggccag gcccgtggtg tagagcgaga agtcgcgcac
     1681 gccgtagcgg tgggcgcgga agtagaaggc ctcgtagggc atggggcggt tgaggagggc
     1741 gaaggtctcc tccatgcggc ccatgaaggc ctcgagctgg gtctcgtcgg ggcgggcggg
     1801 gcggtgggcg acgctgctgc ggaacgactg tgtctccacc tcctgcaggc agatgatgtc
     1861 gggcaggggc tccaacgtgg ccagtgcggc ggccacccgc cgcttgggcc ccagcgtgct
     1921 ggcgagaccc cgcaaggcgt gcccgaagta gcgcacgttg tagctgacga tgcggagact
     1981 atcggtcatg ctcatcaccc acgccgcgtg gaagaaggac gcccgaagga aggtaggacc
     2041 tggcccggcc tggggggagg ggcctggggg caggcatcca agggggcggc gggtgagccg
     2101 ccggaggcgg ggtggacccg tccaccaggc gggcgggcgg ggcgaggggg tgttaaagga
     2161 gtcggcacgc catgacgcct cctccttccc gcttccacgg aaccgatacc tacctctcca
     2221 gcgagggcct ccaggccgcc gtcaactgcg cgctgacgct ccagcgtccg ttgctggtgc
     2281 gcggcgagcc gggcacggga aaaaccctcc tggccgaggc cgtggcccag agcctgggcc
     2341 tgcgcctgct cacctggcac gtgaagagca ccacgcgcgc ccaggacggg ctctacgtct
     2401 acgacaccgt gcagcgcctg tatgactcgc gctttggcga cggggacgtg cgcgacatcc
     2461 gccgctacat ccgcctgggg ccgctgggcg aggcgttcgc ctcgaaggag cgcgtggtgc
     2521 tgctcctgga cgaggtggac aaggccgacg tggagttccc caacgatctg ctccacgagc
     2581 tggaccggat gcgcttccgc gtcacggaga cgaacgagga cgtggtggcc acgcaccgtc
     2641 cggtggtcat catcaccagc aacaacgaga aggagctgcc ggatgccttc ctgcgccggt
     2701 gcgtcttcca cttcatcgac ttcccggacc aggagctgat gcggcgcatc gtcgaggtgc
     2761 accacccgaa cctggacgcg tcgctcacgg agcagtcgct caaggtgttc tacgagctgc
     2821 gcaacttcac gcggctgcgc aagcgcccgt ccacgagcga actggtcgat tggatcgccg
     2881 tgctcaaggc caacggtgtc acccaggtga agctggacga gcagttgccc ttcctggggg
     2941 cgctgatcaa acgtgagcag gacctgatgg cggtggcgga cgcgttcgga cgcggccggc
     3001 ggaccaaggc ctgagcggag cgaccatgtt cctgcccttc ctctacgaat tgcggcggcg
     3061 cggggtgccg gtgggcgcgc acgaggcgat ctccctggcg ggggcgctga aggcggggct
     3121 gcatgacagc tcgctggatg gcttctacca cgtggcgcgc gcgctgctgg tgcacgcgga
     3181 gacgcacctg gatgcctttg atcaggcctt cctggcgcac ttcaagggag tggaggtggc
     3241 ggggcagcag ctcaccgagg agctgctcga gtggctcaag gaagcgcggg agcggcacga
     3301 gctgacgccg gaggagcggg cgctgctgga gcacttcgac gcggaggaac tggagaagct
     3361 cttccagcag cggttggagg agcagcgcga gcggcacgac ggtgggacga agtggattgg
     3421 gacggggggg gcgtcgccct tcgggcactc ggggcagccg cgcgagggct tccgggtggg
     3481 aggccccgcg gccagtggca gcaagcaggc gatgcggctg gcgggggcgc gcgcgtacca
     3541 gggctaccgg ggcgacgtgg tgctggacac gcggcagatg gcggtggcgc tgcgcaagct
     3601 ccgggccttc acgcgcgagg gggcgccgga cgagctggac gtggagggct ccatcgcggc
     3661 gacggcgaag aacgcgggcg agctggaggt ggtgacgcgt ccgccgcgca agcccaacac
     3721 gcgcgtggtg ttgatgatgg acgtgggcgg ctcgatggac ccatatgccc acctggtgag
     3781 tcggctcttc tccgtggcga agcaggccac gcacttcaag gagctgcgca cctactactt
     3841 ccacaactgc gtgtatggcc gcgtgttcga gaacgcgacg ctgacggggg gcatcagcgt
     3901 gccggacctc atgggacagg tggggcggca ctacaagctg gtgatggtgg gggacgcgct
     3961 gatggcgccc tacgagctga ccctgcgcac ggacgtgtat ggccgctatg cgctggaggg
     4021 gggcaaggaa gggctggtgt ggctgatgga gctggcgagg cacttcgagc gcagtgcctg
     4081 gctcaacccc gagcccatcc agacgtggag gggcaacacc attgccgccg tgcggaacgt
     4141 gttcgacatg ttccccctga cgcttgacgg gctgggtgag gcggtggggc acctgaccaa
     4201 ggggaagatg gtgcgcggcc ggaagtaggg gcctggagac gtcgctgggt tcaagcttcc
     4261 tcgtcgggca ggagcgtgcg cagcagctcg tcgtcaggat tgagcgggcg ccagccgggc
     4321 ggtggcggcg tggcgcggag cgttgccctg gcccgtgcga cgcgctcctc atgggtttca
     4381 ggggtgtagg cagaccacga gccaagtgcc tcggcgacct tgaaacggtt ggcgtcgtcc
     4441 atcacggccg gccagccgtc ggggacgctc tgggacaaga ggcgcacgag tacatcacgc
     4501 acgaagcgcg tgacttgctt gcgctgctct gcctcggcga ggagcccgct caacacctgc
     4561 accccggcga cgtcctcctc gcccagctcc tcggcgagca catgcaaagg cacggcggga
     4621 cgcgcctccg cgaaggccgt gagcgagtcg aaaccacgct cacgaacccg ctcgcacagg
     4681 cgcaccttcc aggggccttg ccaggcactc ccctctgtca tgctcctctc ccggggacga
     4741 agttcatcgg gattttagga ggatggtgcg cggccggaag taggggccgc gcgacgccgc
     4801 cctctcgagt caccccgtca ctgcagcacg aacgtgttcg actcgccctt gtggccggcg
     4861 atgtcggtga cgaggatgac cacgtccgac tggatggagt tgaccacgac ctgctgcgtg
     4921 agcactccgt ccacgaaggg ctcgctcacg cgcgggccga tggtgccgcc ggcccctgtc
     4981 tccaggcgca cgttgccgcg gaacgccgcc gcgttggcgc cggtcgcgcg caccgtcagc
     5041 gtgaagggct ccaggcgctt ctgcgggccg atggggtcga tgctgtagcc ctccggccac
     5101 tccccctcga cgacggtgag gccgcccggg cgctcggtgg tacggccgtc cccgagagtc
     5161 accttcacgt cgtagctgcc gggcgggagc atcgacggaa cgcgggtgga gatgacgccc
     5221 tcgggcgaga tggcgagcgt gggcacctcg agcgctccga tgcgcaccga cacctgggtg
     5281 tccaccttga cggtcccctt gtcgtagtcg accgtcgcgg gcaggaccaa ctcggtgtcg
     5341 agggcgagcg ccgtggcctc gctcgcacgc atctccgatg gcgagaccga gcggatgacc
     5401 ggctcgggcc agtcccggca agccaggggc aagaccagcg cggcgatgga gacgagcttc
     5461 ctcatggcag ctgatacctc acaccgagga gcccctgcac acccgtcgag cgcccgatga
     5521 caaaggggat gtacgcctcg ccgaacccca ctcgcgcgtc gaggaacggc tcgatcgccc
     5581 ccagtgggaa gcgcaactgg gcccccgcga gcaactccca gccgatcgcc gagcgcacgg
     5641 aactcgcgga gaagtcgctg gagaggtggt gcagcgccag gagtggcccc acgccgacgc
     5701 gtacgtccac gccgaggtgt gccatccgca cgaggttcat ccgcccgacc gcgaggagtg
     5761 ggagggagtg cagggcggag accgccactc cggtgccggg gatgtcctcg cggaagcgcg
     5821 ccagccgcca gccgagctcc acgtcgatgg agaagcgacc ccagccgggc ggcgtcaggg
     5881 tcagctgcgc cgagccctgg gggcctcggt tgaagccacc gccgtagaac ccaccacccg
     5941 cgagcgcgag ggcgtatcgc gtctgctccg cggactgcgt tgcggccggt cgggtcccgg
     6001 tgcgcgaagg cgctgtcggc gagggcttgg ggctcgtctc ccgcgcaggc gccttcggct
     6061 tcttggggga ggttccgcgg gaggacccct ctggagcagc cacggccgcg gtagagctga
     6121 gcaggaagag gagcgcgagc caacgcatgg agaagggggt ccgcgggggt cggcgccgca
     6181 gacgcgggag aagagaaccc agtcggcggc ggttgtcgag ccccttcgtg cccgtcaccc
     6241 gagaggtatt cacccaggtg gtggggctgc tggtgcacca cgggctgggt gaggtggtgg
     6301 ggcacctgac caaggggcgc atggtgcgcg gccggaagta gggcccagca acgccgccct
     6361 ctcacagggg gaggtctaga cttcctcgtc aggcaggagc gtgcgcagca actcgtcgtc
     6421 agggctgagc gggcgccaac cgggcggtgg tggcgtggcg cggagcgctg ccctggcctg
     6481 catgacccgt tccttgtggg tttcaggcgt gaagctggtc cacatggcga aggactgggc
     6541 caccgtgaaa cgggatgatt cgtccagtat ggcgggccaa ccctctggga ggttttgcga
     6601 caaaattcgc acgagtacat cacgcacgaa acgcgtgact tgcttgcgct gctccgcttc
     6661 ggccagtaac ccgcccatca cctgaactcc ggcgacgtcc tcttcgccca gttcctcggc
     6721 gagtgcatgc aacggcacgg cgggacgcgc atccgcgaag gctgtgagcg agtcgaaacc
     6781 acgctctcga atccgctcat acaggcggac cctccagtta ccttgccagg cgctcccctt
     6841 tgtcatggtc ctctcccggg gacaaggttc atagggattc tatggctttc caccgagcta
     6901 tgctgccgcg agattcgata atcgtttgag actggagtgt tgcgcgcatt caatacacag
     6961 agagggtgaa ccggatacac gcgagctgtg gtgccagcgt tgaagtcaaa agagacatgc
     7021 ggtttagctc aatcgaggaa tcgccgccac cagcggcgtg cagtgtcagg aggacaatcc
     7081 cgccaggaca ggtaatgggg gaaggggagg agccagggct caagcacacg tgccagttcg
     7141 cgccaggccg gtaacgtgtt gccttggctc acgtctcccg cttcgggctc cgggctcagt
     7201 accaccaaag ctcgttcttc ctccagggct gtcaccgtgg tggtcggcgc gtgcagccgg
     7261 gagcggagcg cctcggctcc gcccacctgc accaacactt ctgggcccag gaaattgagc
     7321 cagtgcaccc cgtccactcg tgcgcccagc gctcgctgcc cgtgggtcac gtccaggccc
     7381 gggtagcgca gtgcctcctc gtgaatgtcc ttcatgacgg gcccccacac gctggacgaa
     7441 tagaacgcca gccccgcgtg ccccgatgca tagggcagca gcgcggccag ttgctcaatc
     7501 tccgctcgca ttttcccgga gccccgtgcc tccatgtact cggtgggcca cgagaaactc
     7561 accagactga cttcgtccgc ctgtggagtg cgccatggta gccgccccca atagaagaaa
     7621 ccgtagccac tcaggccccc ctctccaccc gagagttcca cggatcgatc gaactgcttc
     7681 ttcactcgcc gaagcacgta ccgttcatca tcgcggacat catccaggaa ccgctcaccc
     7741 cggggcgggg acaactcgga gcggatgaaa tcccagccct gcgcatcgag cggaaataga
     7801 tcgtcttcgc cttccacgtc gcaccactcg gacagaatct ccggcccctg ccccacgcta
     7861 ctcaagtaca tgtcgagcgc acggttcacg cctgcggaga ggtccacgtg atcaaaaggc
     7921 aaatgcagca cgagccggac cacgtcccgc tggacgagca cttcaccacc gggcgttgcg
     7981 gcgtaatggc ggatacgggg aaggcgatgg ctcatcggct gattcccaac tgaggagtga
     8041 tgagggcacg ggatggatgt tgcgtcagcg gttcatgatt gtcccagatg ctccatccga
     8101 acgtcgagtt ccttgtagcc gccggccccc ccgcgctccc cccgtgtcaa ctcacggtcg
     8161 gggcactcgc ccgacatccc gatcccgagc gccacgttcc agtcgtccct ggcggggcat
     8221 ggtcgtcacg tcgccacatg cgcaggtgct cttggactcg ggtgctcgtc cggtgacctg
     8281 gaggacaacg ccgcatttcg gacatgacgg gctccgcatg ggcattttgt ctccatgtcc
     8341 ccttcgccgc ggaagtgccg gagcctgctc cgggcggagc aaggtgcgcc gcgctccgtt
     8401 gatgctcggg aggccacttc acctgttgtc gggcccgtgg agccccatca ctgggtcttc
     8461 tcgatgttcc gtgggaaact tgcgttgccc gccacccggg atttcgctag gaaaaacatt
     8521 gcttcccccc caggctttcc tctccgactc tcggagcgtc cgacgcgggc catggtcgcc
     8581 gcggggaatc gtccagcgag gagcgtcctc ccatgaacac cgccgtgacc tcgtctcccc
     8641 ccgcctccgt cagggaggcg ccaggcgggt tgccgctgct tggccatgct ctccggctgg
     8701 ttcgctcccc tctcgattat ctgcagtcgt tgagtggact cggtgacatt gtccagctcc
     8761 gggtcgggcc ctctcccttg tatgtggtta cttctcctga gtgcatccat caggtgctgg
     8821 tcacccaggc cgagagtttc gagagggggc gcatcttcga caaggcgaca gtcgccatcg
     8881 gcaaggggct cattgtctcc aacggagctt ttcaccggcg gcaacgaaaa ctcctacagc
     8941 cggggttcca ccggccgcgc atccacggct acatggagac gatccaccgg caagtgggcg
     9001 cgcagattgc cggatggtcg ccgggtgccc acctctcgtt gcgtgaggag atgcatcgtc
     9061 tgacgctcaa ttcggtcacc cggacgttgt tcggcgcgaa caccgaggag cgcatcaccg
     9121 ccgagatcgg cgactacatc gacgccgcca actcatgggt ggggctccac accctgctgt
     9181 ctggccgttt cttcgagcgg ctgccaatgc caatcaaccg ggccttcgtg cgcaagaagg
     9241 cccggttcaa tgagatcctc gatgagttca tcgaatcgcg gcgcgcggat ggccgtgacc
     9301 agggagatct gctgtccgcg ttgttggcgt cacaggatga cgagaccggc caggggatga
     9361 gcgatgaaca gctccggatg gagatctccg gtctgttcgt tgccgggtcc gagaccacgg
     9421 cgaccgcgtt gacctggctc ttctacgaag tgggacgcca ccccgaggtg gaagcgcggc
     9481 tccatgccga ggtggacgcc gtgctgggtg gcagggccat caccccggac gacctgcccc
     9541 ggttgcagta cctccagaac gtgatctccg agacgctgcg ccggcactcg cccatctggg
     9601 tgttcacgag gcgtaccacc cgtgccctgg aactggcggg cacccacctg ccggccgggg
     9661 ccgaggtcat catcagcccg atgatggtcc accgcaaccc acatctctac tccgagccgt
     9721 tgcggttcga ccccgaccgg tggttgccgg aacggatgca ggagattccg cgtcacgcct
     9781 tcattccctt cggggacggg aaacacaagt gcatcggtga ctacttcgcc cgcaccgaga
     9841 tggtgatcgc cgtcgccacc atcgccgccc ggtggcggct cgtcccggtg cccggccacc
     9901 gcgttcggga ggttccccgc gcggtcttgc gacccaacca ggtcctgatg accgccgttc
     9961 cccgttcctc cacacctgtt tcctaggagc gccgttgcag atggacaccc agcgtgccgc
    10021 gatcgagttc cggtttccgt tccctcgtga cctcagtccc gacatcgaac aggcccaacg
    10081 tcacagcgtc gaatgggccc gccagatggg attggccacc acagacttcg cgctcgggca
    10141 actggaggcg tggaattggg gtcgtctcac cgggcactgt ctacccaccg ggcgcggtga
    10201 catcctggac ctggccacgg agtggatcac ctggggattc ctctatgacg accagttcgc
    10261 cggccctctc gggaaccagc cggagcgggt ggcccgaatc accgagaaca tgattggcgt
    10321 tctctactcc acgtccggga ctccggggga gaacgcggcc gcgcgaggca tcgcggacat
    10381 cctccagcgg ctcaccccga agatgtccgc gacctggatg gcccggttcc gcgatcactt
    10441 gaaatggtac ctcatcgggg tgctgcggat gaccaccttc cgcaaccgcc tcggcgagat
    10501 cgacacccgg accgcgttcg agctccgtcg cctcgatatt ggcatgaacg ccatgattga
    10561 cttcatcgag gtcgcggagg gcttcgaggt gcccgcgtct gtcattggag ccagccagct
    10621 ccaggcgctg cgccaatgcg tggtcgacat cgtgctgcta cagaacgacg tcttctccct
    10681 gcccaaggac cggcaccagc aagaggtcaa cgtggtcctc gccatggaac gcgcggagaa
    10741 gctcaccacc gcccaggcac tggaacgcac cgcggccctg gtcgacgaga cggtccagcg
    10801 gttcctcacc gtcaaggctg ggatgcccgt cctctacgac accctcggtc ttggcgctac
    10861 cgaccgtgcc cgtctggacc ggtacatcca ctgtctcgag ctcatggctc acggctccgt
    10921 ctattcacat gccgagtgcg tccgttattc caccaggccc gaacacaccc gacccatcgc
    10981 gggccggggc ttcatccagg atctgcacct ggacgcgggc atcgagctgg cgcacgaact
    11041 cacccgaacg aaccgggggt gagcccctgg cccggggcac tgcacgccta gtaacggcgg
    11101 aacggatcgc cgtgggcgct gtagtcgaag taccaggtgt tccagttgtc gatcagcacg
    11161 tattgctgga cctgatccca gctcagcggg atgaggggtt tgctcaaaat caccatgtcc
    11221 ttcttgctga tggacgagag gtagtagaga tcggtccgcg actcattgat gacacgggtg
    11281 cgctggtact tgaagctgga ggcgcagctc ttgcccgcct tcgtggcgca gtgggcgtac
    11341 accagcgcga cctgatagat atagaaggtc gcgggcccct gcagcgtcgc ggtccagctc
    11401 tggatcgtct gctgggacca ggacgacgac ttcgagaacc cggtctcgat gctggagctg
    11461 gtattgacga tgtcgatgtt ggcgcccacc gagtagctcg cgttgacctc cttcgtgaag
    11521 gtctccgtga ggcccacggt ctgggtcgtg gcgtagtggt gggtggcgcc gctcggatag
    11581 gtatacgtgt tcacgtactt caggtaggcg aagatcggcc gcgtgtaggt gccccagctc
    11641 tgggtcttga tgtagatgtc gccatagacg gtctcgccat ccacccagca tcccggcggc
    11701 ggatcctggt tctcgaggca cgagtcgatg ccgacgtcac cgcccacggc ccagggatag
    11761 ctcgtcgagt tgagctggcc cgtgacgatg ttcggcgcgg tgaccgccga tttctgatgc
    11821 cggaggaagt cgctcacatt cctcagctcc agaaagccgg agtcttgctg ggtcacgctc
    11881 acgggttttt cgtggctcat ggtggaaccc cccactcggg cccatgtctt catcggcccg
    11941 attccctccc tccggatcat cccggcaagc tccccgagct gtcgagtggg ccagggggtg
    12001 gatcgccatg aaccctcaaa agaagacaat ccatcccggt gtgcttcaat gtacggtgtt
    12061 cggaggtatg gaattggact cgaggacggg gagaacgcgc gtggacgtcg tctggacgga
    12121 ggaggtgtga gtccggatgc gccctcggcg ccggggttgc tcgcggtgga tctcgggctg
    12181 cgttcgggat tggccctcta tggccaggac ggacggttgc gctggtaccg ctcgcagaac
    12241 tttggctccc cgtcgcggct caagcgcgcg gtgcccgcgg tgttgcactc ggccgggccg
    12301 ctcgcgtggt tggtgctgga gggtgggggg cccatcgccg aggtgtggga gcgcgaggcc
    12361 ctccggcggg cgcttccggt gctgcgcgtg tccgcccagg actggcgggc gcggctgctg
    12421 tacgcccgcg agcagcgcag cggaggtgtc gccaaggacg ccgccggagt gctcgcgcgc
    12481 cgggtgattg actggtccga tgcgccccgg cccacctcgc tgcggcacga cgccgccgag
    12541 gccgtgttgc tcgggctctg gggcgcgctg gaggtggggt ggttggcgca ggtgccgccc
    12601 gaggttcgca ggtagggcgg ggccgcggtg ctcacttcga cgtcttggtc gtccgggtga
    12661 agggttgcac ggtacgtccc tccgcggagt cctggaggag ggtggcgagc cgcttgagcc
    12721 gcgtctcttc cttcttggcg ctcgtgatcc agtggagggc cgatcgctgg taccagggcg
    12781 cctgcgcctg gaagaagctc caggccttct tgttcgcctt caattgcttg tcataggcct
    12841 cgggcagcgc gatgtcttcc tgctcgtggg aatagattcc cgagcgctcc gccgaccggg
    12901 cctcgaaggc tcgcaggccc gcgggacgca tcaattcctg ctcgatgagt tcctggacgc
    12961 gttggatgtt gacgctgctc cagatgctgc gtggcttccg gggagtgaag cggatggtgt
    13021 agctgtgctc gtcgtgccgc ttgcgcaccc cgtctatcca gccaaaacac agcgcctgat
    13081 ccaccgactc gggccacgtg atgctggggc ggcccgaatc cctcttgtag aacccaacca
    13141 gcaactccgg ctgctggtca tggtgcttct cgagccaggc acgccagtcg gcgggagtcg
    13201 cgaagaaggt cggtttcgac gggggcttcg agggcggctt catggtgccg gggagtatac
    13261 ggaccgcgcc ggctggggca gcatgctccg cccatgcgct cattcctcct cttcccgatc
    13321 ctcctgctcg gcacctccgt ctcggccgcc gagcctgcct ccaccctccg cttcgcctgg
    13381 cccaaggggt tgaaggcccg ggtggaggtc cacatccagg gcgagcggga agcgggagac
    13441 cgcacgcagc gccacgatgc ccgggccacc ttcaccctct ccacccagct tcaaggcgag
    13501 gagttgcagg tgaagcggga ggacttctcc gggtggaagg ggactctgcc cgcgagaatg
    13561 gggtctccca cggatcggct ggtggatcgc atcccgctgg tgcgcgtctc gcgccagggc
    13621 gagttcctgg gcatcgaggg ggcggcgaag gcgcgcgagg ccttcgccag cgaggtgaag
    13681 ctggagtctc tcgacacggc caaccgccgc gtcttcggca tggtgacgac ggacgaggcg
    13741 ctgcgcgcgg tcgcgctcga cttctggaac atgagcgccg gcgcctggcc gcggctgaat
    13801 ctcggtccgg gcaagtcgcg ggagctgcgc agcccgaccg ccgttcccca gctcggaggt
    13861 gggaagctgg acctggtcac caccttccgc tgggtgggcc cggcggcgtg cacccccgac
    13921 gagaaggagc cgcgctgtgt ggagctggtg ctcaagtcca atccggattc cgagcaggcg
    13981 aagaagcttc tgcagcaggc gttgaccgct cagtccggca atggccccgt caccgagtcc
    14041 ttcgagtcga cccaggaact gcgcgcggtg gtggagccgg ccaccctcgt tccccaccgg
    14101 ctgacgctgc ggcgctccag tcagatgcgc ttgcgctcac cgcagggcaa gagcgagtcg
    14161 ggacgcgagc agaccgagcg cgcctacgtc ttccactaca cctcgcccgc cgccccctga
    14221 cgccgcggct cgctacttcg cgccgctcaa ccaggagccc cagcgcacga gccgggagcc
    14281 gccctcgaac tcgcgcttgc cgcccttctc cacgcgctcg gtgctctcgg cgagcggctg
    14341 gaagcgcgcc tcgcgcgcca gccccgccag cgtgggggac cacgggtcgg ccgcgtacgt
    14401 ctccgagagg acgcgctggg tgctcccgtc gttctccgtg cgctgcgccg tgagcgcggg
    14461 caccgcgtgg ccctcggcct cgaaggtgcc gcgcgtaccg gcggccgcgg tggcgggggg
    14521 ccatggcacg gccaccgctt cccacaccag tcccgtcaac acctcctcga ggggctcggg
    14581 ctcggcctcg gcgaagttcg tgcacggcgc ggcctgggtg tccagcgggg cctcggtgcg
    14641 caggagatag ccgcgctcgg cgccgaagca cacgcgcgtc agggtgggcg tggggccttg
    14701 ctccaggcgc cggtcataat aggtgccgga gcccagggga cgctccagcg cgggcgcggc
    14761 ggggctggcc gtggacgagc cctcgcggaa gtcgcgcagc gtccactcgc tgccgcccgg
    14821 gacgtggaag cccgcggtct ccgtgcgcgc gctgagcagc ccccgggtga ggtagagcgg
    14881 tccgggctcg gtggcgtaca cgcgcgagac gagcgggcca tccaccgggc gcgagtcctt
    14941 ctcgaagcgc tgggcgtccc aggctcggcc ggcgacggtg gggcgctcgg cggcgggctt
    15001 gcccaggggg ggcacttcaa tcgggcgcgt cacgtccgag cgcaccggca gcagttgcgg
    15061 ccaggcgagc cataccgggg cgaggggctt gccggcctcg tccgtgaagg acacgtccac
    15121 ccacacccag ggctgctgca cggccaccac ctcgagcgtc accaggccac gcagcgagcg
    15181 ggccgtgcca cccggggccg cgccctgcca ggccgagaag gtgtaggtga cggcatcccc
    15241 cacccgagcg cgctgccacg gggacgtcgc cgaggggatg gggggctctg gaggggtggg
    15301 ggcgaggcca ccggacttca tgccctggca tcctgcgagc aggacgagcg ccatgcccag
    15361 gggcacggag gagcggaaag ggaaacgcat tcgcatgggg gacttgatac accgggggtg
    15421 aagcccctcc catctttcgc tggagccgcg tgcatgtccc cgtcgttgcc cgtccgccgc
    15481 gtcgttctct acaagcatgg cgttggctac ttcgagcgcc ggggcacggt ggagggccga
    15541 gagacgctcc acctggactt caaggcgcgg gacatgaacg acgtcctcaa gtccatgacg
    15601 gtgttggacc tgtcgggcgg ctccgtgtcg gcggtgagct acgactccac ccagcccctg
    15661 gagcagcggc tccaggacat caccctgcgc attcccgagt cgggcagcct cacctcgctg
    15721 ctcgggcagg tgaagggcgc gcgggtgcgg gcgcgcgtgg gcacggagca gctcgtggag
    15781 ggcgtcatcg tggggctcga ctccatgtcc gtggccgagg gcgacacggt ggtggagcgg
    15841 ccctacctga cgctgctggt gggcgcggcg ctgcgcggct tcgatctgct ggaggtggcg
    15901 gagctcacct tcctggatga cgccgtgcgc gcggacctgg agttctacct ggccacgatg
    15961 ctctcctcgt acaagaagga cagcaagcgc gtgtcggtgc tcaccgcggg cgagggcaag
    16021 cgcgagctgt tcgtgtccta cgtgctggaa gcgccggtgt ggaagacgag ctatcgcatc
    16081 ctcctggagg agggaaagcc gccggtgctc cagggctggg cggtggtgga caacaccggg
    16141 gacgaggact gggagcaggt ggagctgacg ctcatggccg ggctgccggt gtccttcgtg
    16201 cacgacctgt acaacccgcg ctacctgcgg cggcccgtgg tggaggtgcg caccgaggcg
    16261 gccgtcgcgc ccgtcattcc cgaggagggc tttggcgcgg tgcgggagat ggccgccgag
    16321 ccggaagcgg cggtggcgcc catggccgcg tccgcccccg ccctcgcgcc cgcccccatg
    16381 atgcgggcca tgtcgagcgg ggggatggcc cggcgcgagg cccaggagcg cagcgcggcg
    16441 gtgcagacgg tgacgaagga ggtgggcgag ctcttcgagt accgcgtgca gcatccggtg
    16501 acggtgcgcc gcaaccagag cgcgctggtg cccatcctcc accggccctt cgagggacgg
    16561 cgggtgctgc tctacaaccg cgccacgcgc gagaagaacc ccctggcgtg cctcgagctg
    16621 cgcaacacca cggggctcac cctggagggg ggcccggtga cggtgacgga gggggacacg
    16681 tacgtgggcg aggcgatgct ggacacgatg aagccggagg accggcgcct ggtgccctac
    16741 gcggtggagc tcgggttcgt ggtgtcggtg gaggatcgct ccgaggaggg gccggtgcgc
    16801 cgggccatgg tgagccatgg cgtgctgacg gtggagttca tgatgatgcg gcgcacccac
    16861 taccatctgc gcaacaaggc gaagcgcgcg cagatcctct tcctggaaca cccgcgcacg
    16921 gagggctggc ggttggatca ggtgggcgcg cccgacgaga cgacggacca ctactggcgc
    16981 ttcacgcggg ggctggccgc ggggggctcg gagacgttca ccgtgacgga gtcctcgggc
    17041 cgccagcgca cctacctgct cgccaacacg ggtctggacg aggtgagctt cttcttgagc
    17101 tcgggcttca tcgacgagcg cgtggcccgg agcctgcggg agatcatctc cctgcgtgag
    17161 cgcgtggcgc ggcgctccga ggaggtgcgc cagcgcacgg aggagcgcgc gcagctcttc
    17221 aaggatcagg agcgcatccg ggccaacatc gaatccctca agagcggcac gccgcagcgc
    17281 gagctggtcg cgcgcttcgt caccaagctc aacgagcagg aggatcggct ggaggggatc
    17341 gcccgggaac tggagcggct cgcgcaggag cagcgcgagg cgcaggagga ggtgaaccgg
    17401 cagatccaac ggctcgcctt cagcacggag ccggtcaagc cgtgagccgg ctcagccgcg
    17461 ctcgagcacg agcggcgtcc agtccccgcg caggctcagg cggggcacgg tgacgccccc
    17521 atccggcgcg gcgaagacgg tgccgtggga atgcccgaag gaccagcgga tgcgctcgcc
    17581 cggcaggcac tggaagcgct gcacgcgccg gggcgtcacg tccacctggg ggatggtggt
    17641 gacgccggga ccgagcaccg cgcgcagtgg catcacgaag cgctgggggg tgtccaccag
    17701 ccggctggca tcccagcgca gcgcccggtt gaacatgccc gccacgtccc catcccagcc
    17761 cgtgtcgccc gccaccttcg ggtctcccgc gtagccggac tccttgctcc acggctggtg
    17821 cccgttgccg ccccggcccg gatctccatc ccaggacgag cggctgaagg ccgggaaggc
    17881 cacgtcccgc cgcaggaagg actttggatc cgtgcgcgga ttccagcccc ggtcccacca
    17941 gcgctccccg agccagggat ccggctcggt gtggccgccc tcgtgccaca cggcgacgtg
    18001 gccgatgtgc tgggtttgca gcgtctcgta gaaggaggag ccggtgaggg tgctggggct
    18061 caccatggag ccgaagtgga tgatgggatc gtccttgccg tgctccagga tgaggaactg
    18121 agagcgcgcc tcgggctcgt cgcgcagggc gcgggtcatg tccagccggc tccagacgcc
    18181 cagccccgcg ggccctggta cctcttcctc cggcatgccc cacaaggacg agagctgcgc
    18241 cacgcgccag ggacggtggg cccgggccac gggctgggca tggcgggcga ccacccccgc
    18301 gaagtgccgg gcgtccagca ggccgagcgt cagcgcgccc gcgccgccca tggagtcgcc
    18361 ctcgacgaag acccggttgg ggtcggcgct gggatagctg cgcagcaccc actccagcag
    18421 cgccagcacc cggcgaacgg tatacggcgg cacgctgccc ctgggcgcgg tgccccggag
    18481 cacgtcctcc gagtagccgt accagtaggt gagctgcgga tcgctcggct ggatgatgaa
    18541 gcggtcccgg gagacctcgg gggagggggg ccagttgccc accccgtgca ggcgcaccgt
    18601 caccggcatg ggctgacggg ccgtggcggc caggggcacc gtcaccaccg cggggaaggt
    18661 acggccggcc tggctcgggc tgtccagcca cgtgtccgtg ggctgctcca gcgtcagacg
    18721 caggctgccc gcctcctcct cgcgctggac gatgcggggc tcgggcgggc gcacggtgtc
    18781 acgcaccgtc accatcaact ccccctggac ccgctgctcc ccgtccacgg cggtgaacgt
    18841 cacctcgtgg cgccacccgc cctggatgaa gtccggctgg aaggtgaggg tgcgcgaggg
    18901 ctcatgccag agggccccgg gcggtaggcc ctccacgaag acgcgggtgc ctggacggcc
    18961 acccttcacg gggagggtga tgcgcagcac ctcctcctcg ttcaccgtct gcggcggcgg
    19021 aagctcgagc gtgaggcccc gaggcaacag cggctcggtc tccatgcggg tcgatgcccg
    19081 cgggggcgag tcccacaacc ccaggctcag cagcgccacg aggagcggcg aatgccgcgc
    19141 aatgccacac cgcaactgcc tgccccagcg catcttgcca cgacctcacg gactgtctcc
    19201 ggggagcggc gggctcccgg ggggtgattg ctgtccaggg agcaagcttc atgccctggt
    19261 gcggacgccg gaacagccga accggcgcgt tcgttcccgg ctcattccgg gcgctctcac
    19321 ggatggtcgg ggtgcaggcg gtgccgccat cccgagcgct gacgggtgag gcgggggttc
    19381 tcgaagaact tgatgaggac gagccccgcg acgaagccac ccacgtgggc ccacaccgcc
    19441 acgccactgc cgccctcggc gctcagggag ttgagctggg gcaggccggt gatgacctgg
    19501 agaccgaacc aatagaggag caccatccac gcgggcaggg ggatcacctt gaagaagatg
    19561 atgaagatga agagcatgtt cacccgcacg ctcgggtaga gcagcaggta ggcccccatg
    19621 acaccggaga tggcgcccga ggctcccacc atggggatgg gcgaggcggg gtccacgagc
    19681 acctgcgccg ccgccgccgc caggccacac acgatgtaga agacgatgaa gcgcagccgc
    19741 cccatgctgt cttccacgtt gttgccgaac acccagaaga agaggcagtt gccgaggagg
    19801 tggctccaac tgccatgcag gaacatggag gtgaggggcg tgagggtgtt gatgggctcg
    19861 cggtccacca cgcacgcgag gccctctccg atttgtacgg ggaagccctc gggggccagg
    19921 ccggtgagct cgcccggcac gagcccgagg ttgcacacgc tggtggccag caccagggga
    19981 ttcaagcccg ctccctggac gagcacccag gtggcgccga tggcgccgag gaacaggtag
    20041 gtgatgacgg gactgcggag cgtggggttg tcgtcactga gaggaatcat cgcgcgagcc
    20101 ccatcatgcc cactgcggcg cgcgggggca gcgctttccc tcttgcttgt gggggagagg
    20161 acgaccgcgc ggggcgcttc ctggcgcggg gggagattct taactgtacg gccatgaacg
    20221 ccatcttctc ccgtcccgtc tcgctgcccg gtctccgcat gcaggccctg gaggcggggc
    20281 ccgcccaggg gcccctcgtg ctcctgctcc atgggtttcc cgaattgtcc gagagctggc
    20341 gcgaggtgat gggcccgctg gcggcggcgg gcttgcgcgt cgtcgcgccg gacctgcgcg
    20401 gctatggcga cacggagcgg cccgagacgg gctacgacct ggacaccctg gcgagggatg
    20461 tcgtccacct ggcgcggcac ctgagtccgg gccggccggt gcacctcgtg gggcatgact
    20521 ggggcggcac catcgccttc tacgtggccg cccatcaccc ggaggtggtg gaccggctgg
    20581 ccgtggtcaa cgccccgcat ccggcgctgc tcgtgcgcga gatggtcaaa cccgcgcaga
    20641 tgctgcgctc ctggtactcc ttcttcttcc aactgccgtg gttgcccgag cggttgttgt
    20701 ccgcgggggg cggtgtcctg gtgtcctgga tgctgcggcg gcagatggtg gacgcctcgc
    20761 gcgtgcctcc gggaaggttg gcggagtacg aggcccactt ctcgaggccc gaggcggcgc
    20821 gcccgcccat cacctactac cgcgagctgt tccgcttcct tttcacgccc gggggccggc
    20881 gccggctgct cgccacgccg cgtgcgcgcg ctcccctgat gctcatctgg ggcgagcggg
    20941 atcccgccct gggcgaggcg ttcacccggg gcctggagcc atacttcgag cagcgccccg
    21001 tcgtgcgtct gctgccggag gagggccaca ccctgccgct cgaggcgccg gacaaggtgg
    21061 cg
//
