LOCUS       NZ_CP022098            21035 bp    DNA     circular CON 17-FEB-2024
DEFINITION  Cystobacter fuscus strain DSM 52655 chromosome, complete genome.
ACCESSION   NZ_CP022098
VERSION     NZ_CP022098.1
KEYWORDS    RefSeq.
SOURCE      Cystobacter fuscus
  ORGANISM  Cystobacter fuscus
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Archangiaceae; Cystobacter.
REFERENCE   1  (bases 1 to 12349744)
  AUTHORS   Rupp,O., Goesmann,A. and Sogaard-Andersen,L.
  TITLE     Sequencing and comparative analysis of myxobacterial genomes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12349744)
  AUTHORS   Bruckskotten,M., Treuner-Lange,A., Rupp,O., Goesmann,A. and
            Sogaard-Andersen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2017) Department of Ecophysiology, Max Planck
            Institute for Terrestrial Microbiology, Karl von Frisch Str. 10,
            Marburg, Hessen 35043, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 09-AUG-2016
            Assembly Method                   :: Celera Assembler v. 8.1
            Expected Final Version            :: yes
            Genome Coverage                   :: 62.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/17/2024 10:04:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,093
            CDSs (total)                      :: 10,016
            Genes (coding)                    :: 9,906
            CDSs (with protein)               :: 9,906
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 26 of 110
            Pseudo Genes (incomplete)         :: 101 of 110
            Pseudo Genes (internal stop)      :: 1 of 110
            Pseudo Genes (multiple problems)  :: 17 of 110
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:24:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 52582
            Orig. end                         :: 73617
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022098.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21035
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21035
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21035
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11035](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11035
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(1464..1478)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            complement(2772..4772)
                     /locus_tag="CYFUS_RS00245"
                     /old_locus_tag="CYFUS_000049"
     CDS             complement(2772..4772)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013736.4"
                     /locus_tag="CYFUS_RS00245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000049"
                     /product="ATP-binding protein"
                     /protein_id="WP_095983363.1"
                     /transl_table=11
                     /translation="MATPESHAVTSGARERASAAAWGSRWPRSGNRLGRRLLLYILLFS
                     TAVSLLGTLVQLGTDYQREVRQLEERFRQIRSSHTQGLAESLWTLDETLLRTQLEGITT
                     LPGIVLAEVDTELGTHYVAGGGEPREFSHDFPLYHGARLLGTLRVGANLAHARAELRSR
                     VLVILATEAGKTFLFGLFAFFLIQRLVTQHLATMAAYARGLDTQHLEAPLVLRRTGTHR
                     VRQDELDEVSAAINEMRESLRKELEERQRSEAASAFLSRAGAVLVESLDLEKVLPRIAF
                     VCVGPLADWCVIDLREDGVLRRVGGAHVDVAKTPLLDELQRRYPLGPDSRVPAAVAMRT
                     GTWVLESRVTRAGLRAWCVDDAHVQLVSELGLGSVLAVPLMSRGHALGAITFAAAGPER
                     YGPAELALAEELARRTAIAIDNARLYRQAEQALRLRETFLSVAGHELRTPLLPLQLRLQ
                     SLLRRGRNAAPLEPEVLLGEIAVAEWQTRRLGLLVDQLLDVSHLIAGNALVLRRKRMDL
                     CKLVEGVLEGVQRQISDSGSEVVRELCSPVEGEWDPRRLELVVMGLVQNALKFGEGRPI
                     DVRVTPREGSVVLVVRDRGMGMSKSEQEHIFDRFSRGVPEQHFGGLGLGLYLTREVVRA
                     HSGSISVESAPGQGTTFTVVLPLGEAPGPVA"
     gene            complement(4759..5955)
                     /locus_tag="CYFUS_RS00250"
                     /old_locus_tag="CYFUS_000050"
     CDS             complement(4759..5955)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF024799.4"
                     /locus_tag="CYFUS_RS00250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000050"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_095983364.1"
                     /transl_table=11
                     /translation="MTTLRWRLGALLAPVLLPLLLLVLILLGAAPPEPAAPARARMRVV
                     FLNALGIGGGFSRQFRGAMHAAAHDLGIELIDIDVGHWPGQILEQARQAVSGPDKPDYL
                     ITSIHRGIGARVLEVAEQAQVPVFVVNSGLALEERARFGGPREHFTWWVGQMVPDDVGA
                     GERLVRLLIDAAQARRRSLERGPVEGPVRLIAIEGQWGDTSAKQRHLGLRQALSGEKDA
                     ELLQSVTAAWQREESRRKTFLLLRRYPELEVIWAANDDLAMGAVQALEEAGRRPGEDVQ
                     VGGIDWTPEALQAVREGKLVTSLGGHFLEGAWALVLLYDHHQGRDFASERLDWRTAFLP
                     ATRANAAGYLEVLARPDWEAFDFRAFSKAVNPRLTHYDFSLQALFAQRHRRMDPNGNP"
     misc_feature    complement(6160..6178)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.15"
                     /tool="antismash"
     gene            6243..7169
                     /locus_tag="CYFUS_RS00255"
                     /old_locus_tag="CYFUS_000051"
     CDS             6243..7169
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS00255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_000051"
                     /product="papain-like cysteine protease family protein"
                     /protein_id="WP_095983365.1"
                     /transl_table=11
                     /translation="MSLTIPPNSVTLPRVTKSSTTEPETQTPPPPPPKLTKELETVKDD
                     YQQALENQKQWLIKYGAPKEQIEALDKAIEQHQESVLDLNNARNSQNNVVALEQKDAGG
                     WNSEAPVLQQEGNSDCGETVAAMFKGAKEGREKVEGERGQGVINDFKSRFTKGDGTTPA
                     EMADMLTSEGLEVKHSTKGLERNVMDEALRNGDKAAVMLDSKISGSPDDASGSPHWVLI
                     DGMDNQGRYLVKDPSNGSSYYAKPEDLANAIDTNQSKSHSGGVLIVGNPDVPTDLAGKN
                     RDNAETLGDKPGKGWGWKNNSQESSDG"
     gene            complement(7191..8960)
                     /locus_tag="CYFUS_RS00260"
                     /old_locus_tag="CYFUS_000052"
     CDS             complement(7191..8960)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020478634.1"
                     /locus_tag="CYFUS_RS00260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000052"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_095983366.1"
                     /sec_met_domain="Pkinase (E-value: 2.4e-35, bitscore:
                     121.3, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDPAQGPSASSSPVPFDPHRGERIGRYEVLSQLSVGGMAELFLG
                     YTSGPGGFRKYAAIKRILPDARSDEQFERMFLDEARITAAFSHPNIGQVFELGQDQGGL
                     FLAMEFIAGQNLDQVIALGRRLGGTLPLGFVLSVVRDVCLALHYAHTFTTPGGKPHPVI
                     HRDVAHKNVMVTYDGMVKLLDFGIAKARGARANTQAGMVKGTTGYMSPEQVRGQPLDGR
                     SDLFSVGVMLHELLTGERLFAAGSEIQEMQMILGASIPDPQPRGGQVSAEIRAVALKAL
                     ARDREQRYATGRDMARALEAAAGPLLFDAEQRAAFMAEHFQKQREGTRQLLQTVDETLD
                     GTSKVAPIASRPEPEPARALEDVRRPGVEKRPVPRRKTEPEVPATPPDRVVTTGRVVTR
                     EFSNAPAAPPDTRETPGLKVAKSSLGLWAGMLVLGGLLGLGAMELRQVFLAEPIPAPPP
                     GSAEDPSPLLPLGPSRPQGPVPLPETAAEPTSPPAEEASKASASTAEATGAASPARPAK
                     QGLLTLVTRPEAEVFLNGRSLGKTPLFKKPVPVGQLRLLLQGQDGKRRELFVPIEQGKP
                     AVLNLTLADLPVR"
     misc_feature    complement(7518..7520)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9123..9138
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     misc_feature    complement(9192..9207)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.68"
                     /tool="antismash"
     gene            complement(9250..9537)
                     /locus_tag="CYFUS_RS00265"
                     /old_locus_tag="CYFUS_000053"
     CDS             complement(9250..9537)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS00265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_000053"
                     /product="hypothetical protein"
                     /protein_id="WP_157758139.1"
                     /transl_table=11
                     /translation="MAFTESVSSEQPAQAFSLYVPFPQQAQMDLLPADTRHTLLGELFQ
                     MAVQAARERDFLPRAAPVTLEFQLAGCDVRLELDAERARLTLVSLSRTWH"
     gene            10001..11035
                     /locus_tag="CYFUS_RS00270"
                     /old_locus_tag="CYFUS_000054"
     CDS             10001..11035
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014394622.1"
                     /locus_tag="CYFUS_RS00270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000054"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_095983368.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 9.9e-36,
                     bitscore: 122.7, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 8.2e-16, bitscore:
                     57.2, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNDSSALAFCREVLPAVSRTFALNIPVLPAPLDTAVLVAYLLCR
                     IADTLEDEVRGPASAVLLAELARLSTLPEGWREDARRFTGEAARELRAQAPEAEVRLVE
                     GTGFVLEALGEHAAPVREHVATCLRLMTEGMGRMGNKGRASGGGLGLDSLEETLEYCYY
                     VAGTVGEMLTRLFEWYSPAIAGRARTLEPRSVAFGNALQLTNILKDVREDLERGFCWLP
                     RPLLAEHGLTPEVLLEPGNRGAALEAHGRLVAVAHRELRQAFEYVLGLPREEHGIRLFC
                     LWPLFLAVMTLRKLYGNGRVLEPGPVKVSRRTVKWVVAATKLLVARDGALKLMFAALTA
                     PLPA"
     misc_feature    complement(10004..10018)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.38"
                     /tool="antismash"
     gene            complement(11039..11638)
                     /locus_tag="CYFUS_RS00275"
                     /old_locus_tag="CYFUS_000055"
     CDS             complement(11039..11638)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630990.1"
                     /locus_tag="CYFUS_RS00275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000055"
                     /product="DUF938 domain-containing protein"
                     /protein_id="WP_095983369.1"
                     /transl_table=11
                     /translation="MKRHAPSAERNRDPLLPVLREVLPAQGTVLELASGTGQHAVFFAR
                     ALPGLTWQPTDVDPTALASIEAWRQEEGPPNLRAPLALDVLAEPWPVERADALVAINLV
                     HISPWEACQGLLRGAGRVLAPGAPLVLYGAWFIEGQTPAPSNLAFDASLRERNPSWGVR
                     ELGAVTAEARRHGLERERVIEMPSNNLTVVFRARAG"
     gene            complement(11635..13581)
                     /locus_tag="CYFUS_RS53715"
                     /old_locus_tag="CYFUS_000056"
     CDS             complement(11635..13581)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="CYFUS_RS53715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000056"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_095983370.1"
                     /sec_met_domain="Pkinase (E-value: 5e-37, bitscore: 126.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGSMLPSAQDDVRGRQMGNYEVLCRLSTGGMAEIFLASRRGLAG
                     FHKPVVLKKILPDIQGQEEFVQMFLDEARVTAAFNHPNIAQVFDLDVAGDELFLAMEFV
                     PGATLLEVARACLAAKEPMPMGLGLAAVRDTALALHYAHTFTDALGEPSPVIHRDVAEK
                     NIMVTYEGVTKLLDFGIAKSVMEVSRTQVGMVKGTSGYMSPEQILGQPLDARSDLFSLG
                     VVLHECLTGARLFPGKAPAAVMNAVLRGPIPEPSRANKAVPPELDAIVLKALARQREDR
                     YATTLEFARELERAVSGLIWLPEQSGALLRRLFAERREQTRQVLAGARTSTGEVKLSAA
                     PADSREGATPAPPAPAPRLPTVSPAPPQASRGPSSSNTDIVPYSPLVPPPAAPVAAGEP
                     RAASPAPRAPARASMERSRPVLPPPTRPRPPGRVDPPPAPEEAREPEKTALVRSRRSMT
                     SEHRASSAAESRPASPEAPASRSPAESRPASPEAPSSRALPTRAMRIPTPDASPRASTA
                     APPSDVEPDEETTRPHRRPALPLLPDDTSEDSSEYPTLPYQTLPSLPPRARAPRTEEEL
                     LLSSGTHSIAASRSGWGLRVALLVLLGLLGLAAMFIALRWDGGLVSSWLLPSPAAQAAP
                     PAASPGPEGSKAP"
     misc_feature    13729..13738
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.64"
                     /tool="antismash"
     gene            13971..16037
                     /locus_tag="CYFUS_RS00285"
                     /old_locus_tag="CYFUS_000057"
     CDS             13971..16037
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002630993.1"
                     /locus_tag="CYFUS_RS00285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000057"
                     /product="PilZ domain-containing protein"
                     /protein_id="WP_232537281.1"
                     /transl_table=11
                     /translation="MATKKVAERMRARDSVLGYRMGPGLAAVASVEGERSPEGRLVQLS
                     PEHLTVCLQRTPALKPGQRANVVLGVGGEATALRAEVMKIHRPAPEALPELSLRFVAPP
                     LAQGRHIVSMLEGWRDEGHLELPHASPIWKERIVRADRIGRIFEALVARRCRGRARSEH
                     GDVELSAALFDKYDARVAWEVRGGVLPPGPFLLEVYGFSSVLRFQVDEAQHEDGLWSVK
                     LPSELVRYRHRRLRRAPAWGGCVARFAHPLWPQVRVQRELMDISYEGLSFATEPGEDLL
                     YPGLVLSEMEVELPGRAPVYVKAEVRNISGTSAGRRCGMKVEPIGDGAAWRMLVEELSH
                     PNTRVSGQWDQGTWDLYERSGYFRLSGKTPADFERMKAEYREAHERLERAPRLGYRVVR
                     PVPQSDTVEASLSWLKPYSGSWMAHHLARHLPAGERCRGTAREALRDIYLRGFEPAQTD
                     PDIKWFLAYCEANVRWVRFTALDFAEWYQHTGQACVLNFHLMEADARREWVMPEGFSLG
                     EPTDEEKQALFARLERTRPVAYREALDLVPERFDLSGLKQQWSGARLGRERHVLVARKD
                     GRAVAVGIMEAAHAGLNLFHVLNGLRIIPLVDASLPEAQQAMLALLAGAAEWYRARGLD
                     VFIHYVEEEHRDYLGEARLTDLGEGRIWILSAQLLPDFIEHLCEATTPRGGDA"
     gene            complement(16075..18906)
                     /locus_tag="CYFUS_RS00290"
                     /old_locus_tag="CYFUS_000058"
     CDS             complement(16075..18906)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015348130.1"
                     /locus_tag="CYFUS_RS00290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CYFUS_000058"
                     /product="kelch repeat-containing protein"
                     /protein_id="WP_095983372.1"
                     /transl_table=11
                     /translation="MDKKRIVRGCIRGSLMVLALAGCGQKASSGGEAPGARSGLLTGSC
                     EVRPPVPPVFEPELEWAWTGSDVMPSHTNVMMAPVVVDTNGDGVPDVVFNSYAGENYIS
                     DGILRAVDGATGVELWAVTKQEHRVRGASSIAAGDLDGDGRVEICTVAQDSRGLLCFEH
                     DGTFKFRTVGPGNNWGGPSLADLEGDGQVEIINGHAVFDHTGALKWLGSDGPGGTTNGP
                     ISFAVDIDQDGKLEVINGRAIYQYDGQPRCVNTDIGHGLAAVANFDADPQGEVVVVWSG
                     YVTLMDDLCQSLWTMPIPGGGVGGTPNIADFDGDGQPEIGVAGTDRYTVFEADGSVKWT
                     STMRDHSSNRTGSSTFDFEGDGRSEIAYADEVRLRIYDGTTGAVRFEVPHSSCTAYEQP
                     IVADVDGDHNAELLVAQNTTCGFGSFAGLRLYRDRKDGWVNTRRVWNQHAYSITHVNED
                     GTLPTHPATAWLSGFNSFRSNSQGSPGTSAFAAPDVRVSDLTATCDATTWTLTLQARVR
                     NTGDAATSAGLKVAFYQGAPASGGQLLGVASLPQALPPAGEASATLKLTTAPDPSARLW
                     AVADDDGTPGAGRELECDEGNNAASLDAGPRCAPSPSRTWVRRGDLLLPRLMHAAALLA
                     DGRVLVAGGFNRTAEVYDPLGATWSATASTLVPHRGHAMTRLADGRVLLVGGSTRANAE
                     LYVPALGEWRAAGLLHKLRYHPTATLLPDGRVLVVGGATSEDGGGMLGSSELYDPAHDT
                     WSLTGTLGTARSRHTATLLPDGRVLVVGGVDGSGNSLASAEVFDPATGSFSPVSATRVG
                     HGVHTATALADGRVLVVGGLAPGVPSAASAELYDSTTDTWTTTGPVRTPRRAHTATLLP
                     GGEVLVAGGYHPSTGILTTAERFDPVSGTWSDTAPMNVDRYGHTATLLGDGTVLAVGGV
                     SNHDSASTESYSP"
     misc_feature    complement(19026..19041)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.75"
                     /tool="antismash"
     gene            19172..20266
                     /locus_tag="CYFUS_RS00295"
                     /old_locus_tag="CYFUS_000059"
     CDS             19172..20266
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CYFUS_RS00295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CYFUS_000059"
                     /product="hypothetical protein"
                     /protein_id="WP_095983373.1"
                     /transl_table=11
                     /translation="MPSMILVLCLAAVLGGAPGGGGSPSADERVQELFQTMHDVEVSIE
                     PLPRPGEPPGDAEDRCPVGADVKISLREPWRQGVACWLPARDDDTRRTLCAAVTRGAPG
                     SRIVSRCLGRRTPVCSRTPLDCSPRQVKRMPSELAPLAGLHARLPPHALPPAEVMALKA
                     LAFRASGRLAWRRPPSGAPSALMHVGRDSPFGFLLKDGRRYRFQDDPRYETAPLWVLDV
                     TSLVGRPAHAFLSYTRQEEPEGSRGDVWLRILEFDEAAGARQLAVKKVGMWFGAGRERR
                     QRIRGSPCAFMGCSRRRGLAGEAWLVPVMASSGQLELRLPRGMSWLGEGRARTGWRGDG
                     GLKELRGEVGAWCWTGEELSRCPR"
ORIGIN
        1 acgcacgggg agcgagcccc gcctggagga agcgctcgcg ggcctgggcc gcctcgcgcc
       61 gcgcctcgcc gcgcgcctcg ggccccgggt cggtcgccca cagggcacgc gccagggcat
      121 agcccgactc ggccagcgcg tccggactca tcgtggggaa ggcgacggcc cggcgcaggg
      181 gctcgatcgc ctcgcgcgtg cggcccagcc gcatcaaggc ctggcccacc ccgtcgtagg
      241 agtactggag gtcctcgtcg tccggagcca gggcctcgcg cttgagggcg agcgcccgct
      301 cgaaggtggc gagcgactcc tcggagcgtc cgagcttgag cagacactgg cccaccccgt
      361 ccagggcgct ggccacctgg gggctgtgct caccgaaggc ggcggtgtgc gcggcgacca
      421 cggcgcgcgc atgctccagg gcccgctccg gctgtcccat ctcgagcagc agcccggcga
      481 gcaggccatg gcgcctgccg gtgtccgggt ggaggggccc cacggcggcc tgggtctgcc
      541 ggagcgcctc ctccaggagc gccaccgccc ggggccgctc gttcatgtcc aacagcacgc
      601 ggccgagctg gaagagggtg cgcgcgcgct tggggtggcc ggggggcagc gccttttcct
      661 ggagggcgcg ggccttctcc agcagggtgc gggcatccgc gtagtgctcc tgggtgatgg
      721 ccgagttggc ccggttcgtc agcaggtcgg cctccagggc cggatctcct cccagacgcc
      781 gcagcgtggc ctcgcccagg cccgcccagc tgtccgcctg cgggaagtgc ttctgcccgt
      841 tctccacgaa gttgagccgg gtggcgatgg acaccttgag ccgatcggcc cgtcccgact
      901 cggcgtcgaa gaaggcctgg gtgagcagcc gcccggactc ggcggccgcg ccgaggttgg
      961 actggagcgc gcccaggtcg tagcgcagct cggcgatgag cggcaggtgg cccgtggcga
     1021 gcacgggggt ctccagcgag aagcccttct ccagggcggg ccggtagcgc cccgcgtcga
     1081 gcatcgcctt caccccggcg agctcccctc cgagccgggc gatctccgcg cggcgcgcgg
     1141 ggtccaccgg caggcgctgc tgcgcggcga gcgactccac gtccgcgcac tcgctcagcg
     1201 agggcagcgc gaacaccgcg tcgagcgccc ggtccacgag cttcgcgtcc gcgtcggcca
     1261 gcacgcccac cacggcccgc atgtcctggc gccgccggtc cagacacacc acgcgctggg
     1321 acaacagctc ctcggtctgc accccgcgca cgcgcgtggc ctcgcacgcc tcggtgctct
     1381 gccgcttcca gtccgccgcg tactcctcca gcacccgggc gacgcgcgtg gccatctccc
     1441 ccgcgccggg tcgtccggtg gcctggaagg ccttgtccag cgtggcgccc gagtcgggcc
     1501 cccacacctc ggccatgagc gcgtcggcgc ccgtgcacac ctgggactgg cggtacacca
     1561 ccccgcccac caccgacagc cccacgcccg ccgcgcacgc cgccgccgcc cagcgctggc
     1621 gctgcacgcg ccgccgctcc tgcgacagcg cctccagcag ctcgcgcatc gaggcgaagc
     1681 gctcctgggg atccagcgac atgccgcgca tgagcgcctg gcgcacccac gtgggcacct
     1741 tggactcgcg cggcggctcc tggatgaggt ccgcggccgg gctgcgcttg accacgggcg
     1801 ccggcgcgac gtccagcgtc tgggtgcgcg ccgagaccag ctcctccctg cgccgcgagg
     1861 tgatgaaggc ccgcatgcgc gtggagtcga aggcgcgctt gcggtagagg ccccagtaga
     1921 gcgccacgca gaagctgaac tggtccgagc gcgcgtcgag ctcgcccccc tcgtactgct
     1981 cgggagacat gtagttgggc gtgcccatca ccacgcccga gcgggtgagg gtggtctcca
     2041 gcatgcggcg ctcgggcggc accaggccct gggcctgctc gggcaggggc tcctcgggga
     2101 cgacggactc ccccatcttg cgcgccaggc cgaagtcggt gacgtagacg cggccgccgc
     2161 ggccgatcag cacgttggcg ggcttgaagt cgcggtgcac cagccccgcc tcgtgcgccg
     2221 cgagcaggcc ccgacccgcc tccaggaaga cctcgagcac ctcgcgccag ggccgctcct
     2281 tctccaacca cccgctgagc gtgccctcgt ccgccatctc catggcgagg aacacgtgct
     2341 cgccccacat gcccacgtcg tggatgggga cgacattcgg gtgggtcacc cgggccatgg
     2401 cctgcgcctc gcgcaacagc ctcgcgcgcg ccgcctccgc gtccgagtgg ccgtccgact
     2461 gcaacagctt gagggccacc ttgcgatcca ggtccggatc gtacgccgag tacacgacgc
     2521 ccatgccgcc ctgtcccaac tgcttgagca gcacgtagcg ccccacctgc gccaccggcg
     2581 gagcgtcctc cacctgggca tcgcggttgg agcggcccgt gttcggcgcc ggctgctcgc
     2641 gcgaatgctt gcttcggaac cggctactcc tggttttacc gtcacccatg gctgtccagg
     2701 attccacctc ggctccatct ttgtaaagac ggggtgccga gacagggcgc gggggtgggc
     2761 ccgagcaccc ctcaggcaac cggccccggg gcctcgccca acggcagcac cacggtgaac
     2821 gtggtgccct gcccgggcgc gctctccacg gagatggagc ccgagtgggc ccgcaccacc
     2881 tcgcgcgtga ggtagaggcc gagccccagc cccccgaagt gctgctccgg caccccccgg
     2941 ctgaagcggt cgaagatgtg ctcctgttcg ctcttcgaca tccccatgcc ccggtcgcgc
     3001 accaccagga ccaccgagcc ctcccggggc gtcacgcgca cgtcgatggg ccggccctcg
     3061 ccgaacttca gcgcgttctg caccaggccc atcaccacca gctccagccg gcgcggatcc
     3121 cactcgccct ccaccgggct gcacagctcg cgcaccacct cggagccgct gtcggagatc
     3181 tgccgctgca cgccctcgag caccccctcc accagcttgc acaggtccat gcgcttgcgc
     3241 cgcagcacca gcgcgttgcc ggcgatgagg tgggacacgt cgagcaactg gtccaccagc
     3301 agtccgagcc gccgcgtctg ccactcggcg acggcgatct ccccgagcag cacctccggc
     3361 tccagggggg ccgcgttccg gccgcggcgt aggaggctct gcagccgcaa ctggaggggc
     3421 agcaggggtg tgcgcagctc gtgcccggcc accgagagga acgtctccct cagccgcagg
     3481 gcctgctccg cctggcggta gagccgcgcg ttgtcgatgg cgatggcggt gcgccgcgcc
     3541 agctcctcgg ccagggcgag ctcggcgggc ccgtagcgct ccggcccggc cgcggcgaac
     3601 gtgatggcgc ccagcgcgtg cccccggctc atcagtggta ccgccagcac gctgcccagg
     3661 cccagctccg acacgagctg gacgtgcgcg tcgtcgacgc accaggcgcg cagcccggcc
     3721 cgggtgacgc gggactccaa cacccacgtg ccggtgcgca tggccacggc cgccgggacc
     3781 ctcgagtccg ggccgagagg gtagcgccgc tggagctcgt ccagcagcgg cgtcttcgcc
     3841 acgtccacgt gcgccccgcc cacccggcgc agcaccccgt cctcccgcag gtcgatgacg
     3901 caccagtcgg ccagcgggcc cacgcacacg aaggcgatgc gcggcagcac cttctccagg
     3961 tccagcgact ccacgagcac cgcgccggcc ctggagagga aggcggaggc cgcctcggaa
     4021 cgctgccgct cctccagctc cttgcgcaag gactcgcgca tctcgttgat ggcggcgctc
     4081 acctcgtcca gctcgtcctg gcgcacccgg tgcgtgcccg tgcgccgcag caccaggggc
     4141 gcctccaggt gctgcgtgtc caggccgcgc gcgtaggccg ccatggtggc caggtgctgc
     4201 gtcaccagac gctggatgag gaagaaggcg aagaggccga agaggaacgt cttgcccgcc
     4261 tccgtcgcga ggatgacgag cacccggctg cgcagctcgg cgcgggcgtg cgccaggttg
     4321 gcccccaccc ggagcgtccc gagcaggcgc gcaccgtggt acagcgggaa gtcgtgggag
     4381 aactcccggg gctcgccgcc gccggccacg tagtgggtgc ccagctcggt gtccacctcc
     4441 gcgagcacga tgccgggcag cgtggtgatg ccctcgagct gggtgcgcag gagcgtctcg
     4501 tcgagtgtcc agaggctctc ggcgaggccc tgcgtgtggc tggagcggat ctgcctgaaa
     4561 cgctcctcga gctgccgcac ctcccgctgg tagtcggtgc cgagctgcac cagcgtgccc
     4621 agcaggctga cggcggtgct gaagagcagg atgtagagca gcagccgtcg tccgagccgg
     4681 ttgccggagc gcggccagcg cgagccccag gccgccgccg acgcgcgctc ccgggctcca
     4741 gaggtgaccg cgtgcgactc aggggttgcc attcgggtcc atgcggcgat gccgctgcgc
     4801 gaacaaggcc tggagggaga aatcgtagtg cgtcaggcgc gggttgaccg ccttcgagaa
     4861 ggcccggaag tcgaaagcct cccaatccgg ccgggcgagc acctccaggt agcccgcggc
     4921 gttggcgcgc gtggcgggca ggaacgccgt gcgccagtcg agccgctcgg aggcgaagtc
     4981 gcgcccctgg tggtgatcat acaggagcac cagggcccac gccccctcca ggaaatgtcc
     5041 tccgaggctc gtcaccagct tgccctcgcg cacggcctgg agcgcctcgg gcgtccagtc
     5101 gatgcccccc acctgcacgt cctcgcccgg gcggcgaccc gcttcctcca gggcctgcac
     5161 cgctcccatc gccaggtcat cgttggcggc ccagatgacc tcgagctccg ggtagcggcg
     5221 cagcaggagg aacgtcttgc gccgggactc ctcccgctgc caggcggcgg tgacgctctg
     5281 gagcagctcg gcgtccttct ctccggacag ggcctggcgc aggcccaggt ggcgctgctt
     5341 cgcggaggtg tccccccact ggccctcgat ggcgatgagc cgcaccggcc cctccaccgg
     5401 cccccgctcc aaggagcgcc gacgcgcctg ggccgcgtcg atcagcagcc gcaccagccg
     5461 ctcacccgcc cccacgtcgt ccggcaccat ctggcccacc caccacgtga agtgctcgcg
     5521 cggccccccg aagcgcgccc gctcctcgag cgccagcccg gagttgacga cgaacaccgg
     5581 cacctgggcc tgctcggcca cctcgaggac gcgggcgccg atgccgcggt ggatggaggt
     5641 gatgaggtag tcgggcttgt cgggcccgct caccgcctgg cgtgcctgct cgaggatctg
     5701 ccccggccag tggcccacgt cgatgtcgat gagctcgatg cccaggtcat gggcggcggc
     5761 gtgcatggcg cccctgaact ggcgggagaa gccccccccg atccccagcg cattgaggaa
     5821 gaccacgcgc atgcgcgcgc gcgcgggagc ggcgggctcg ggaggcgccg cccccaggag
     5881 gatcagcacg aggagcagca aggggagcag cacgggcgcg agcagggcac cgaggcgcca
     5941 ccggagcgtg gtcatgggca agcagctccc ccctttgcgc gtgcgcccgg gaagacatca
     6001 ggacgaggag gggtgagcgt agcgtcgcct ggaaccgaca ggaacgggcg tcaccgcaca
     6061 acgctcaccc ggcggcgtca gcagcgtcag cgtctcctgt cctacatttc gggcctccgg
     6121 ctcggctgcc tggttggtca cggagagagc aaacttcgag ccctactgga aacaatctcc
     6181 gaaacgttgc gatactaggg agaagctgaa cccgcgcatt tcccgccccc gggaggtccc
     6241 ccatgagcct gacgattccc ccgaactccg tcaccctccc acgagtcacc aagagctcca
     6301 ccaccgagcc cgagacccag actcctcccc cgcctccgcc caagctgacc aaggagctcg
     6361 agacggtcaa ggacgactac cagcaggcgc tcgagaacca gaagcagtgg ctgatcaagt
     6421 acggcgcccc caaggagcag atcgaggcgc tggacaaggc gatcgagcag catcaggagt
     6481 cggtgctgga tctgaacaac gcgcgcaact cgcagaacaa cgtggtggcg ctggagcaga
     6541 aggacgcggg cgggtggaac agcgaggcgc cggtgttgca gcaggagggc aacagcgact
     6601 gcggcgagac ggtggccgcc atgttcaagg gagccaagga gggccgtgag aaggtggagg
     6661 gcgagcgggg tcagggcgtc atcaacgact tcaagagccg cttcaccaag ggggatggaa
     6721 ccacgcccgc ggagatggcc gacatgctca cctccgaggg gctcgaggtg aagcacagca
     6781 ccaagggcct ggagcgcaac gtcatggacg aggcgctgcg caacggcgac aaggccgcgg
     6841 tgatgctgga ctcgaagatc tccggcagcc ccgacgacgc gtcgggcagc ccgcactggg
     6901 tgctcatcga tggcatggac aaccagggcc gctacctggt gaaggatccc tccaacggct
     6961 ccagctacta cgccaagccc gaggatctcg ccaacgccat cgacaccaac cagagcaaga
     7021 gccactcggg cggcgtgctc atcgtgggca acccggacgt ccccacggat ctggccggca
     7081 agaaccggga taacgccgag acgctcggcg acaagcccgg caagggttgg ggctggaaga
     7141 acaactcgca ggagagctcg gacgggtagg cccggcgggc gggccgcgcc tcagcgcacg
     7201 gggaggtccg ccagcgtcag gttgagcacc gctggcttgc cctgctcgat gggcacgaac
     7261 agctcgcgcc gcttgccatc ctggccctgg aggagcagcc ggagctgtcc caccggaacg
     7321 ggcttcttga acaggggcgt cttgcccagc gagcgcccgt tgaggaacac ctcggcctcg
     7381 ggccgggtga cgagcgtgag caacccctgc ttcgccggac gcgcggggga agccgccccg
     7441 gtcgcctccg cggtggaagc ggacgccttc gaggcctcct cggccggagg gctcgtcggc
     7501 tccgccgcgg tctcgggtaa cggcacgggt ccctggggac gcgagggccc gaggggaagc
     7561 aggggagagg gatcctccgc ggagcccgga ggcggagcgg ggatcggctc ggccaggaag
     7621 acctgccgga gttccatggc tcccaggccc agcaacccgc ccagcaccag catcccggcc
     7681 cacaagccca gggagctctt cgccaccttg aggcctggcg tctcccgcgt gtccgggggc
     7741 gcggcggggg cgttcgagaa ctcccgggtg accacccggc ccgtggtgac cacccggtcc
     7801 ggcggggtgg ctggcacctc cggctccgtc ttgcgccggg gcacgggccg cttctcgact
     7861 cccggacgac gcacgtcctc gagagcgcgc gcgggctccg gctccggccg cgacgcgatc
     7921 ggagccacct tcgacgtgcc atccagcgtc tcgtccacgg tctgcagcaa ctggcgcgtg
     7981 ccctcccgct gcttctggaa gtgctcggcc atgaaggcgg cgcgttgctc ggcgtcgaag
     8041 agcaggggac ccgccgcggc ctccagcgcc cgcgccatgt cccggcccgt cgcgtagcgc
     8101 tgctcccgat cgcgcgccaa cgccttgagc gccaccgcgc ggatctccgc cgacacctgc
     8161 cctccccgag gctggggatc ggggatggac gcccccagga tcatctgcat ctcctggatc
     8221 tccgacccgg cggcgaacag ccgctcgccc gtgagcagct cgtggagcat cacccccacg
     8281 gagaacagat cgctgcggcc atccagcggc tggccccgca cctgctccgg cgacatgtac
     8341 ccggtggtgc ccttcaccat gcccgcctgg gtgttcgccc gggcgccgcg cgccttggcg
     8401 atgccgaagt ccagcagctt caccatcccg tcgtacgtca ccatcacgtt cttgtgggcc
     8461 acgtcccggt ggatgacggg atggggcttg cccccgggcg tggtgaaggt atgcgcgtag
     8521 tgcaacgcga ggcacacgtc gcgcaccacc gacagcacga agcccagggg cagcgtcccc
     8581 ccgagcctcc ggcccagggc aatcacctga tccaggttct gccccgcgat gaactccatc
     8641 gccaggaaca gccccccctg gtcctgcccc agctcgaaca cctggccgat gttcggatgg
     8701 ctgaacgccg cggtgatgcg cgcctcgtcc aggaacatcc gctcgaactg ctcgtcgctg
     8761 cgcgcgtccg gcaggatgcg cttgatggcc gcgtacttgc gaaagccccc cggccccgac
     8821 gtgtagccca ggaacagctc ggccatgccc cccactgaca actgggagag aacctcgtag
     8881 cgtccgatgc gctctccccg gtggggatcg aacggcacgg gagaagatga tgcggagggc
     8941 ccctgggcag ggtcggacat gggcgcgcag catagcccac agcccctgtg gacggcctgt
     9001 ggagcaaacc gggagtccct gtggacaacc ccaccgcgct ccccaccctt gtggatggcc
     9061 ggggataagc gccaacttcc ccacatgtag catcctcggg aatcctcaag gatgacgagc
     9121 gcttacggac ttttccacaa gcccacaccc cctgctgtta cctcttctag atcaagatca
     9181 ctctctatcc agtgaagaaa cagcggggcc tggggacaac ccgaactgtg gacaaaggcc
     9241 cccggtggct cagtgccagg tgcgcgacag ggacaccagg gtgaggcggg cacgctcggc
     9301 atccagctcc agtcgcacgt cgcagccagc cagctggaac tccagggtga cgggggcagc
     9361 gcgcggcagg aagtcccgct cccgcgccgc ctggaccgcc atctggaaca gctctcccaa
     9421 cagggtgtga cgcgtgtccg ccggcagcag atccatctgc gcctgctgcg ggaacgggac
     9481 gtagagcgag aaggcttgcg ccggctgctc ggagctcacg gattcagtga aagccatgca
     9541 gccctggaat gccagaagca taccgggaac gagccgtgtg attccgagag gttacggggt
     9601 ttcccgagga ggaaggccgt agaaatgaca ggaatttcag gattggagga gtccaccggc
     9661 ggacggaggg agcccctttc ccccgggtcg ggcagtttcc gagcggccag gggtccacac
     9721 tccctcctgg aagaatgagg ggtcctccaa ggagtgcgtg cacccggggg cgggctgggg
     9781 taatgccgac cctcgtgacg cgaacccggg agatggatgg acggctgtcg gcccgggtgg
     9841 acgatccggt ggcggcagaa accgggagtc acgcgaagga gctcccttgg agttgagtcc
     9901 cccccgtggc ccccagccct accgcgaagc ccctcttagt acgcatcagg tctccgagac
     9961 cagggacaac ccgagagatt ccctcgcgtc gaccatgccg atgttgaacg attcttccgc
    10021 gctcgccttc tgccgcgagg tgctgccggc ggtgtctcgc accttcgcgc tcaacatccc
    10081 cgtgctgccc gcgccgctgg atacggcggt gctggtggcc tacctgctgt gccggatcgc
    10141 cgacacgctg gaggacgagg tgcgggggcc ggccagcgcg gtgctgctcg cggagctggc
    10201 gcgcctgagc acgctgcccg aggggtggcg ggaggacgcc cggcgcttca ccggggaggc
    10261 ggcgcgggag ctgcgcgccc aggcgcccga ggccgaggtg cggctggtgg agggcacggg
    10321 tttcgtgttg gaggcgctcg gggagcacgc ggcgccggtg cgcgagcacg tggccacgtg
    10381 tctgcggctg atgaccgagg gcatggggcg catgggcaac aagggccgcg cctcgggtgg
    10441 gggcctgggc ctcgactcgc tcgaggagac cctggagtac tgctactacg tggcgggcac
    10501 ggtgggggag atgctcaccc ggctcttcga gtggtactcg ccggccatcg ccggacgcgc
    10561 gcgcacgctc gagccgcgct cggtggcgtt cggcaacgcg ctacagctca ccaacatcct
    10621 caaggacgtg cgcgaggacc tggagcgggg cttctgctgg ctgccccggc cgctgctggc
    10681 cgagcacggc ctgacgcccg aggtcctgct ggagccgggc aaccgtggcg cggcgctcga
    10741 ggcccatggc cggctggtgg cggtggcgca ccgggagctg cgccaggcgt tcgagtacgt
    10801 gctgggcctg ccccgcgagg agcacggcat ccgcctcttc tgcctgtggc cgctgttcct
    10861 cgcggtgatg acgctgcgca agctgtacgg caatggccgg gtgctcgagc ccggaccggt
    10921 gaaggtgtcg cggcgcacgg tgaagtgggt ggtggccgcg acgaagctgc tggtggcccg
    10981 ggatggggcg ctcaagctca tgttcgccgc gctcaccgcc ccgctgcccg cgtgagcctc
    11041 accccgcccg ggcgcggaac accacggtga ggttgttgct gggcatctcg atgacgcgct
    11101 cgcgctcgag gccgtgccgc cgcgcctcgg cggtgacggc gcccagctcg cgcacgcccc
    11161 aggaggggtt gcgctcgcgc agcgaggcgt cgaaggcgag gttgctcggc gccggggttt
    11221 gtccctcgat gaaccaggcg ccgtagagca cgagcggcgc gcccggagcg agcacccgcc
    11281 ccgcgccccg gagcagcccc tggcaggcct cccaggggga gatgtgcacc aggttgatgg
    11341 ccacgagcgc gtccgcgcgt tccacgggcc agggctcggc cagcacgtcc agcgcgagcg
    11401 gggcacgcag gttgggcggg ccctcctcct ggcgccaggc ctcgatgctc gcgagcgcgg
    11461 tgggatccac gtcggtgggc tgccaggtga gcccgggaag ggcgcgcgcg aagaagacgg
    11521 cgtgctggcc ggtgccgctc gccagctcca gcacggtgcc ctgggcgggc agcacctcgc
    11581 gcagcacggg cagcaggggg tcccggttgc gctcggcgga aggggcgtgg cgcttcatgg
    11641 agccttggag ccctcggggc ccggcgaggc ggcgggcggg gccgcctggg cggccgggga
    11701 aggcagcagc cacgaggaca ccagacctcc gtcccagcgc agggcgatga acatcgccgc
    11761 gagccccagc agccccagca gcaccagcag ggccacccgg agcccccacc cggagcgcga
    11821 ggccgcgatg gagtgggtgc ccgaggacag caggagctcc tcctcggtcc tcggcgcgcg
    11881 ggcgcgcggg gggagggagg gaagggtctg gtaggggagg gtggggtatt ccgacgagtc
    11941 ctcgctcgtg tcgtcgggca ggaggggcag ggcgggacgg cggtggggcc gggtggtctc
    12001 ctcgtccggt tccacgtcgg agggtggcgc ggcggtggat gcgcgggggg acgcgtccgg
    12061 agtggggatg cgcatggcgc gcgtgggcag ggcgcgggag gagggagcct cgggggaggc
    12121 ggggcggctc tcggcggggg agcgggaagc gggggcctcg ggggaggcgg ggcggctctc
    12181 ggcggcagag gaggcgcggt gctcggaagt catggagcgc cgggatcgga cgagggccgt
    12241 cttctccggc tcccgcgcct cctcgggggc gggagggggg tccacgcggc ccggcgggcg
    12301 tggccgggtg ggtggaggca gcacgggccg tgagcgctcc atggaggcac gcgcgggtgc
    12361 gcggggcgcg ggagaggcgg cgcggggctc acccgcggcg acgggagccg ccggaggagg
    12421 caccaggggc gagtagggga cgatgtccgt gttggacgac gagggcccgc gcgaggcctg
    12481 cggaggagcg ggggagacgg tgggcaggcg gggcgccgga gcgggagggg ccggggtggc
    12541 gccttcgcgg gaatcggccg gggcggcgga cagcttcacc tcgcccgtgg acgtccgggc
    12601 gcccgcgagc acctgccgcg tctgctcgcg ccgctcggcg aagaggcgcc gcaggagcgc
    12661 cccgctctgc tcgggcagcc agatgaggcc gctcacggcg cgctccagct cgcgcgcgaa
    12721 ctccagcgtc gtcgcgtacc ggtcctcgcg ctggcgcgcc agggccttga gcacgatggc
    12781 gtccagctcg gggggcacgg ccttgttggc gcgcgagggc tcggggatgg ggccgcgcag
    12841 caccgcgttc atcaccgccg cgggcgcctt gcccggaaac agccgcgccc ccgtgagaca
    12901 ctcgtgcagc accaccccca ggctgaacag atcgctgcgc gcgtccagcg gctggccgag
    12961 gatctgctcc ggcgacatgt agccgctcgt gcccttcacc atgcccacct gggtgcggct
    13021 cacctccatc acgctcttgg cgatgccgaa gtccagcagc ttggtgacgc cctcgtacgt
    13081 caccatgatg ttcttctcgg ccacgtcccg gtggatgacg ggcgagggct cgcccagcgc
    13141 gtccgtgaag gtgtgcgcgt agtgcagcgc cagcgccgtg tcgcgcaccg ccgcgagccc
    13201 cagccccatg ggcatgggct ccttggccgc caggcacgcg cgcgccactt ccaggagcgt
    13261 cgcgcccggc acgaactcca tggccaggaa cagctcgtcc ccggccacgt ccagatcgaa
    13321 tacctgcgcg atgttcgggt ggttgaaggc cgcggtgacg cgcgcctcgt ccaggaacat
    13381 ctggacgaac tcctcctggc cctggatgtc cgggaggatc ttcttgagca ccaccggctt
    13441 gtggaacccc gccaggccac gcctggaggc gaggaagatt tccgccatgc ctcccgtgga
    13501 caggcggcag agcacctcgt agttgcccat ctgccggccg cgcacatcgt cctgcgcgga
    13561 gggaagcatc gaaccagcca ttcgagaaat ccaagcctat aggacccgcc gccccaggcg
    13621 gaagccatcc ccatgttttt cgcgtgagag cgtaaccgga gtgcattcca gtgaaacctt
    13681 gaacgcgggt tttcctgctt tgaacggatc aggaacacga gtttttcttg gtttttgaga
    13741 cacccgggga tggcgggaaa gagttggcga ggtgtcagaa ggcgtccgcc ctgcgcacga
    13801 gggggcgaag gagcaagccc ctcccgaagg acagggaaga tgtcgtcggg tgagcacctg
    13861 cgggggggcc gatgggtgct cgacgattgg agggcccggc gacatccggt gaggctgcac
    13921 aagccgggga gtgtgtccac attggcggaa ttccgaaggt ggagttcccc atggcgacga
    13981 aaaaggtggc ggagcgcatg cgtgcccgag acagcgtcct gggctatcgc atgggtccgg
    14041 ggttggcggc ggtggcgtcc gtggaaggtg aacgttctcc ggagggacgg ttggttcaac
    14101 tgtcgccgga gcatttgacg gtgtgcctgc agaggactcc ggcactcaag ccggggcagc
    14161 gggccaacgt ggtgttgggg gtgggagggg aggcaacggc cctgagggcc gaggtgatga
    14221 agatccatcg gccggcgccc gaggcgctgc cggagctgag tctgcgcttc gtggcgccgc
    14281 cgctcgcaca gggtcgccac atcgtctcca tgctggaggg ctggcgagac gagggccacc
    14341 tggagctgcc gcacgccagc cccatctgga aggagcggat cgtgcgcgcg gatcgcatcg
    14401 gccgcatctt cgaggcgctc gtggcgcggc gctgccgggg cagggcgcgc tcggagcatg
    14461 gggacgtgga gctgtccgcg gcgctcttcg acaagtacga cgcccgggtg gcctgggagg
    14521 tgcgtggggg cgtgctgccg cccggcccct tcctgctgga ggtgtatggc ttcagctccg
    14581 tgctgcgctt ccaggtggac gaggcgcagc acgaggacgg gctgtggagc gtgaagctgc
    14641 cctccgagct ggtgcgctac cgccaccgtc ggctgcgccg cgccccggcg tggggcggct
    14701 gcgtggcgcg cttcgcccat ccgctctggc cccaggttcg cgtgcagcgc gagctgatgg
    14761 acatcagcta cgagggcctg tccttcgcca ccgagccggg ggaggacctg ctctacccgg
    14821 ggctcgtgct gagcgagatg gaggtggagc tgccgggccg cgccccggtg tacgtcaagg
    14881 cggaggtgcg caacatcagc ggcaccagcg ccggccgccg ctgcggcatg aaggtggagc
    14941 cgatcggcga cggggcggcc tggcgcatgc tcgtggagga gctgagccac ccgaacaccc
    15001 gcgtgtccgg acagtgggat cagggcacgt gggatctcta cgagcgctcg ggctacttcc
    15061 ggctgtcggg caagacgccc gcggacttcg agcgcatgaa ggccgagtac cgcgaggcac
    15121 acgagcgcct ggagcgggcg ccccggctgg gctaccgcgt ggtgcggccc gtgccccaga
    15181 gcgacacggt ggaggcgagc ctgtcctggc tcaagccgta ctcgggcagt tggatggcac
    15241 accacctggc gcggcacctg cccgcgggcg agcgctgccg cggcacggcg cgcgaggccc
    15301 tgcgcgacat ctacctgcgc ggcttcgagc cggcgcagac ggatccggac atcaagtggt
    15361 tcctcgcgta ctgcgaggcg aacgtgcgct gggtgcgctt cacggcgctc gacttcgccg
    15421 agtggtacca gcacacgggc caggcatgcg tgctcaactt ccacctgatg gaggcggacg
    15481 cgcgccggga gtgggtgatg cccgagggct tcagtctggg cgagcccacg gacgaggaga
    15541 agcaggcgct gttcgcgcgg ctcgagcgca cacgcccggt ggcctaccgc gaggcgttgg
    15601 acctggtgcc cgagcgcttc gacttgtcgg ggctcaagca gcagtggagc ggggcccggc
    15661 tgggccgcga gcgccacgtg ctggtggcgc gcaaggacgg ccgcgcggtg gcggtgggca
    15721 tcatggaggc ggcgcacgcg gggctcaacc tgttccacgt gctcaacggg ctgcgcatca
    15781 tccccctggt ggacgcgtcg ctgcccgagg ctcagcaggc gatgctggcg ctgctggctg
    15841 gcgccgcgga gtggtaccgg gcgcgcggcc tggacgtgtt catccactac gtggaggagg
    15901 agcaccggga ctacctgggc gaggcccggc tcacggacct gggcgaggga cgcatctgga
    15961 tcctctccgc ccagctgctg ccggacttca tcgagcacct gtgcgaggcg acgacgcccc
    16021 ggggaggcga tgcatgaggc accgcccccc gggggctttc cggggggcgg gtgctcaggg
    16081 ggagtaggac tcggtggagg cggagtcgtg gttgctcacg cctcccaccg cgagcaccgt
    16141 gccatcgccc aggagcgtgg cggtgtggcc gtagcggtcc acgttcatgg gggccgtgtc
    16201 gctccaggtg ccgctgacgg ggtcgaaccg ctccgcggtg gtgagaatgc ccgtggaggg
    16261 atggtagcca cccgccacga gcacctcgcc gccgggcagc agcgtggccg tgtgcgcgcg
    16321 gcggggcgtg cgcacggggc ccgtggtcgt ccaggtgtcc gtggtggagt catacagctc
    16381 ggcgctcgcg gcggacggga cgccaggggc caggccgccc accacgagca cccggccatc
    16441 ggccagcgcg gtggcggtat gcacgccgtg gcccacccgg gtggcgctca cgggcgagaa
    16501 gctccccgtg gcggggtcga acacctcggc cgaggccagg gagttgcccg agccatccac
    16561 gccgcccacg acgagcaccc ggccgtcggg caggagcgtg gccgtgtgcc gcgagcgagc
    16621 ggtgcccagt gtgcccgtga gcgaccaggt gtcgtgggcg gggtcgtaca gctcgctgga
    16681 gcccagcatc ccgccaccgt cctcggaggt ggcgccgccc acgacgagca cccggccatc
    16741 gggcaggagc gtggccgtgg ggtggtagcg caacttgtgg agaagtcccg ccgccctcca
    16801 ctcgccgagc gccgggacat acagctcggc gttggcgcgg gtggagccgc ccacgagcag
    16861 cacccggcca tcggcgagcc gggtcatggc gtggccgcga tgcgggacga gggtgctcgc
    16921 ggtggccgac caggtcgcgc cgaggggatc gtacacctcc gccgtgcggt tgaagccgcc
    16981 agccaccagc acccggccat ccgccaggag ggccgcggcg tgcatcagcc ggggcaggag
    17041 caggtcgccg cggcgcaccc acgtcctgct cggagaaggg gcgcaccgcg ggcccgcgtc
    17101 caaggaggcg gcgttgttgc cctcgtcgca ctccagctcg cggcccgccc ccggagtgcc
    17161 gtcgtcatcg gccacggccc agagccgggc gctcggatcc ggggcggtgg tgagcttcaa
    17221 cgtggcgctc gcctcgcccg ccgggggcag ggcctggggc agcgaggcga ctcccagcaa
    17281 ctggccgccc gaggcgggag ctccctggta gaaggccacc ttcaacccgg ccgaggtcgc
    17341 cgcgtccccc gtgttgcgca cgcgggcctg gagcgtcagc gtccaggtcg tggcgtcaca
    17401 cgtggcggtg aggtccgaaa ccctgacatc gggcgcagcg aaggcggacg tgccggggct
    17461 gccctggctg ttggaacgaa aggaattgaa gccgctcaac caggcggtgg cggggtgggt
    17521 ggggagggtg ccatcctcgt tcacgtgggt gatggagtag gcgtgctggt tccagacgcg
    17581 ccgggtgttc acccacccgt ccttcctgtc ccggtacagg cgcaggcccg cgaacgagcc
    17641 gaagccacag gtggtgttct gcgccacgag cagctcggcg ttgtggtctc catccacgtc
    17701 ggcgacgatg ggctgctcgt aggcggtgca ggagctgtgg ggcacctcga agcgcaccgc
    17761 gccggtggtg ccgtcgtaga tgcgcagccg cacctcgtcc gcgtaggcga tctccgagcg
    17821 cccatccccc tcgaagtcga aggtggacga gcccgtgcgg ttggagctgt gatcgcgcat
    17881 ggtactcgtc cacttcacgc tgccgtccgc ctcgaagacg gtgtagcggt ccgtgcccgc
    17941 gacgccgatc tccggctggc cgtctccgtc gaagtccgcg atgttggggg tgccacccac
    18001 gccgccaccc ggaatgggca tggtccacaa ggactggcag agatcatcca tcaacgtcac
    18061 atagccgctc cacaccacca ccacctcgcc ctggggatcg gcgtcgaagt tggccaccgc
    18121 cgcgagccca tggccgatgt cggtgttcac gcaccgcggc tgcccgtcgt attggtagat
    18181 ggcccggccg ttgatcacct cgagcttgcc atcctgatcg atgtccaccg cgaaggagat
    18241 cgggccgttg gtggtgcctc ccgggccgtc gctgcccaac cacttgagcg ctcccgtgtg
    18301 gtcgaagacg gcatggccgt tgatgatctc cacctgcccg tctccctcga ggtccgccag
    18361 cgacgggccc ccccagttgt tgcccggccc cacggtgcgg aacttgaagg tgccgtcgtg
    18421 ctcgaagcac aagaggcccc ggctgtcctg ggccacggtg cagatctcca cccgcccgtc
    18481 cccgtcgagg tcacccgccg cgatgctcga cgcgccgcgc acccggtgct cctgcttcgt
    18541 caccgcccac agctccacgc ccgtggcgcc atccaccgcg cgcaggatgc catcgctgat
    18601 gtagttctct cccgcgtagg agttgaagac gacgtccgga acgccatccc cgttggtgtc
    18661 caccaccacg ggcgccatca tcacgttggt gtgcgagggc atgacatcgc tgcccgtcca
    18721 ggcccactcc agctcgggct cgaagacagg gggcacggga ggcctcacct cacagcttcc
    18781 cgtgaggagt ccgctccggg caccgggtgc ttccccgcca ctcgaggcct tctgcccgca
    18841 gccggccaac gccaacacca tcaggcttcc gcggatacac ccgcggacga tcctcttctt
    18901 gtccatggct ctccccccat gcacggcgca gccggtcgct cgttcgcggt ccacctgcgc
    18961 cgacttccgc cgacaacaat caatacataa agatgtacaa cccggataaa ttggaaactc
    19021 atggtgtgag aaaagactca actcgggcag gggtgcggac gggcccttcg tcctgaaccc
    19081 ttcacatgtg agccttatcg gagcgggttt tgttggacgg acggcagcgg gagcagcagg
    19141 gtattgcctt ggattttcgt ggagaagggt gatgccctcg atgatcctcg tgctgtgtct
    19201 cgcggcggta ctgggcggtg cgccgggcgg aggcggctct ccttccgccg acgagcgtgt
    19261 ccaggaactg ttccagacga tgcacgacgt ggaggtctcg atcgagccgc tgccccggcc
    19321 cggggagccg cccggggacg cggaggaccg gtgcccggtg ggagcggacg tgaagatctc
    19381 cctgcgagag ccctggcgtc agggggtggc ctgctggctg ccggcgaggg acgacgacac
    19441 gcggcgcacg ctctgcgcgg ccgtgacgcg gggcgcgcct ggaagcagga tcgtgagcag
    19501 gtgcctgggc cgccggaccc ccgtgtgcag ccggacgccc ctggactgct caccccgcca
    19561 ggtgaagcgg atgccttccg agctggcgcc gctggccggg ctccacgcgc ggctgccgcc
    19621 ccacgcgctg ccacccgccg aggtgatggc gttgaaggcc ctggccttcc gggcctcggg
    19681 caggctggcc tggcgccgac ctccctcggg tgcgccctcg gccctcatgc acgtggggcg
    19741 ggacagcccc ttcggcttcc tgttgaagga cggacgccgc tatcgcttcc aggacgatcc
    19801 ccggtacgag accgctcccc tgtgggtgct cgacgtgacg tcgctcgtgg gacggcccgc
    19861 gcatgccttc ctctcctata cgaggcagga ggagccggag gggagccggg gagacgtctg
    19921 gctgcgcatc ctggagttcg acgaggcggc gggcgcgcgt cagctcgcgg tgaagaaggt
    19981 ggggatgtgg tttggcgccg ggagggagcg gcgccagcgg atccgcggct ctccctgcgc
    20041 gttcatgggg tgctcgcgcc gccggggcct cgcgggcgag gcgtggctcg taccggtgat
    20101 ggcctcgtcc ggccagctcg agctgcgcct gccccgggga atgtcctggc tcggggaggg
    20161 acgcgcgcgg acgggctggc ggggtgacgg gggattgaag gagctgcgcg gcgaggtggg
    20221 cgcgtggtgc tggacgggcg aggagttgag ccgttgccca cggtaggatg agcggcccgt
    20281 gccgaagacg actcctcccg ccgtgacgct gcccgccgag caggcgcgcg cgttcctcgt
    20341 cagccacctc gccctcgccg cgcccgtgca tcccccgggc gccgagggcg tgcgcgcgct
    20401 gctgcgccac ttgcgccaca tccagttgga tcccctcgac gtcatcggca ccaacgcgga
    20461 cctggtggcg ctcgcgcggg tggacggcct cgtacggggg gacgtgtacc gccacctcta
    20521 cccgggccat gccttcgagc attgggcgaa ggagcgctgc ctgctgcccg ccgatgcctt
    20581 tccccactac cgcgagcgct ccctggaggc gccgtggtgg aggcacgcca cgcggctcga
    20641 gcggctgccc gcgaccgtgc tgggcgccgt gctggaggag ctggaggccc atggcccgct
    20701 gacggccgcg gagctcaccg accacggcgc ggtggatccc ctcgactgga gtgggtggaa
    20761 gggcacggcg aaggccacca ccatggcgct cgaggtgctg tggacgcgct gtgacatcgt
    20821 cgtgtgcggc cggactcccg ggggcaagcg ctacgacgtg ccgcgccggg ccctgccgga
    20881 ggtggcgcat gtctcgccgg ggtacaccac ggaggaaggc ttcatgcgct gggccctcgg
    20941 cgagcgcgtg gaggcggcgg gcctgctgtc gcgcgcggcg ggggcgcact ggtccatgct
    21001 gtccccggtg agaggctcgg ccctgccgga ggccc
//
