LOCUS       NZ_CP022753            24281 bp    DNA     circular CON 23-OCT-2024
DEFINITION  Nocardiopsis gilva YIM 90087 chromosome, complete genome.
ACCESSION   NZ_CP022753
VERSION     NZ_CP022753.1
KEYWORDS    RefSeq.
SOURCE      Nocardiopsis gilva YIM 90087
  ORGANISM  Nocardiopsis gilva YIM 90087
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Nocardiopsidaceae; Nocardiopsis.
REFERENCE   1  (bases 1 to 6142152)
  AUTHORS   Yin,M. and Tang,S.
  TITLE     The complete genome sequence of Nocardiopsis gilva YIM 90087
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6142152)
  AUTHORS   Yin,M. and Tang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-AUG-2017) Yunnan University, School of Medicine, 2
            North Cui Hu Road, Kunming 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 208.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002263495.1-RS_2024_10_22
            Annotation Date                   :: 10/22/2024 21:04:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,549
            CDSs (total)                      :: 5,470
            Genes (coding)                    :: 5,345
            CDSs (with protein)               :: 5,345
            Genes (RNA)                       :: 79
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 61 of 125
            Pseudo Genes (incomplete)         :: 66 of 125
            Pseudo Genes (internal stop)      :: 5 of 125
            Pseudo Genes (multiple problems)  :: 6 of 125
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:05:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 888663
            Orig. end                         :: 912944
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022753.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24281
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyanobactin"
                     /region_number="7"
                     /rules="(cyanobactin_synth or TIGR03678 or
                     cyanobactin_precursor)"
                     /tool="antismash"
     cand_cluster    1..24281
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cyanobactin_synth or TIGR03678 or
                     cyanobactin_precursor)"
                     /kind="single"
                     /product="cyanobactin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24281
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14281](+)"
                     /cutoff="20000"
                     /detection_rule="(cyanobactin_synth or TIGR03678 or
                     cyanobactin_precursor)"
                     /neighbourhood="10000"
                     /product="cyanobactin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14281
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cyanobactin_synth or TIGR03678 or
                     cyanobactin_precursor)"
                     /neighbourhood="10000"
                     /product="cyanobactin"
                     /protocluster_number="1"
     misc_feature    complement(71..85)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    complement(545..560)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.98"
                     /tool="antismash"
     gene            complement(784..2007)
                     /locus_tag="CDO52_RS04330"
                     /old_locus_tag="CDO52_04320"
     CDS             complement(784..2007)
                     /EC_number="1.6.5.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017580050.1"
                     /locus_tag="CDO52_RS04330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04320"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_051060888.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.4e-39, bitscore:
                     131.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHRILVLGAGYAGLTTTARLARRLHPHDARVTLVNANPHFVERV
                     RLHQLATGQRLADLPLRKLLDGTGVQLIVGRVASVDPERRHVRVTGESRDELSLEYDTL
                     VYALGSMADLDVVPGVAEHAFSVSDTEGAAALHHRAADLGAAGGVLGVVGAGLTGIEAA
                     TELAETYPRLRVRLLSTDAPGDGLSLAAQRHLRRVFRRLDIDVRADSPVTEVQQDRLMT
                     TRGDAVPLDATVWTTGFRVPALARESGLAVDHDGRILVDQTMRSHSHPNVYAVGDAALA
                     RGPGRLASQQLRMACGTGVPMGWQAADAIAARITGRDPHPFRFRYAAQNISLGRRDGLI
                     QFVRPDDSPHRAILTGRTAARWKEAVVRGSVRVMRYPGLYLAPPRRRELPDHAQGREQE
                     AGPVLRRP"
     misc_feature    2143..2158
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.52"
                     /tool="antismash"
     gene            complement(2201..3169)
                     /locus_tag="CDO52_RS04335"
                     /old_locus_tag="CDO52_04325"
     CDS             complement(2201..3169)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620742.1"
                     /locus_tag="CDO52_RS04335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04325"
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="WP_232524381.1"
                     /transl_table=11
                     /translation="MSAPLDGEHVSEFESHRPRLFAVAYRLLGSATEAEDAVQDTYLRW
                     SDTDRNLITTPAAWLTKVLTNLCLNRLTAARARREAYVGPWLPEPVLTPDSSLGPLETV
                     EQRESVSMALLVLLERLTPAERAVFVLREAFAYRHREIAEVLDLSEANCQQLNRRARQK
                     LHDEQGHRPVSETPHEQRNRIAELFFAAAHSGDLTGLERLLADDVTAWADGGGKIGAAR
                     RPIFGSTRVARYLHGLFRQIDAIVEERFGPGLEICAAEVNGEPALLVTVDSGPLAVAVL
                     ELHDDRIAAIRTIVNPDKLAFIGAQLSRSHAGVLLWPTTPR"
     misc_feature    3584..3593
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.11"
                     /tool="antismash"
     rRNA            3781..5313
                     /db_xref="RFAM:RF00177"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="CDO52_RS04340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="CDO52_04330"
                     /product="16S ribosomal RNA"
     gene            3781..5313
                     /locus_tag="CDO52_RS04340"
                     /old_locus_tag="CDO52_04330"
     misc_feature    3824..3840
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.19"
                     /tool="antismash"
     misc_feature    complement(3883..3898)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.99"
                     /tool="antismash"
     misc_feature    complement(3887..3904)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.75"
                     /tool="antismash"
     misc_feature    complement(4988..5004)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.98"
                     /tool="antismash"
     rRNA            5713..8798
                     /db_xref="RFAM:RF02541"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="CDO52_RS04345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="CDO52_04335"
                     /product="23S ribosomal RNA"
     gene            5713..8798
                     /locus_tag="CDO52_RS04345"
                     /old_locus_tag="CDO52_04335"
     misc_feature    complement(5837..5857)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.81"
                     /tool="antismash"
     misc_feature    complement(7070..7085)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.99"
                     /tool="antismash"
     misc_feature    7667..7680
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.59"
                     /tool="antismash"
     misc_feature    complement(7668..7681)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.29"
                     /tool="antismash"
     misc_feature    complement(7669..7682)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.22"
                     /tool="antismash"
     misc_feature    complement(7670..7683)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.1"
                     /tool="antismash"
     misc_feature    complement(7676..7685)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     misc_feature    7817..7830
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.96"
                     /tool="antismash"
     misc_feature    complement(7912..7922)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    complement(8819..8835)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.66"
                     /tool="antismash"
     rRNA            8970..9087
                     /db_xref="RFAM:RF00001"
                     /gene="rrf"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="CDO52_RS04350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="CDO52_04340"
                     /product="5S ribosomal RNA"
     gene            8970..9087
                     /gene="rrf"
                     /locus_tag="CDO52_RS04350"
                     /old_locus_tag="CDO52_04340"
     misc_feature    complement(9153..9167)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.08"
                     /tool="antismash"
     gene            9694..9855
                     /locus_tag="CDO52_RS27170"
     CDS             9694..9855
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CDO52_RS27170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_017621325.1"
                     /transl_table=11
                     /translation="MQEKMHQPGMPLLADPVERKLNTTAASAADGVDQSIFGGITWKDI
                     PFAGDSDE"
     gene            10001..12067
                     /locus_tag="CDO52_RS04355"
                     /old_locus_tag="CDO52_04345"
     CDS             10001..12067
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyanobactin: cyanobactin_synth"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03895.1"
                     /locus_tag="CDO52_RS04355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04345"
                     /product="PatA/PatG family cyanobactin maturation protease"
                     /protein_id="WP_033302031.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 4.6e-30, bitscore:
                     103.2, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="cyanobactin_synth (E-value: 3.6e-156,
                     bitscore: 518.8, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKLSIIPGLSELWRLTKGDDRVGVAVVDGRVGAGHPAFAGSGLA
                     SVEGVWPSDGATGAKAAHGTSVAGVLFGQHDGPVPGVAPGCRKVSVPAFSDRWARTSQL
                     DLARGIELALDEGVHVINISGGQLASAEEAEDPLARAVRRCKESNVLVVAAAGNDGCFC
                     DHVPAALPSVLAVGALDDEGRPLPSSNWGPGNTRQGILAPGQNIPVPVPGGGVALQTGT
                     SLAAPVVSGVAALLLSLQLRDGREPDPRAIGELLMTTADPCDLGDADACARFLNGKLNI
                     TKAVTTVTSNETDVSVAHSQAEPVSPIPETATGRPEQAVPSCDCGCDQAPAAAATVPTA
                     QAALQAPTDPAAAPATTPAAGSAAVTLSSPAPAPVPSPAPAPPPAPTPPPQATSTVTTS
                     SDDPARVPAQRLAYAQGVLGYDFATEARRDSFKQLMAPVEVGGAHVPANPYDPNHMVAH
                     LRENPSESSALIWTLNLDLTPIYAIEPNGGYTVGVYERLVDFLSRQLECDDGANFVDRV
                     SIPGKLPGRTVKLFSGQEVPVVEVELKRGLYGWSVTSLANAVAEAGAAGAKKGNPSADT
                     LRAAVAEFLTRVYYDLRNFGATSRDRALNFAATNAVQARDTLAQALSQGLALQDIDVEK
                     SPFARPDSDCWDVKLRFFDPENSRRAKRVYRFTVDVKDVMPVTVGDIRSWPES"
     gene            12093..12293
                     /locus_tag="CDO52_RS04360"
                     /old_locus_tag="CDO52_04350"
     CDS             12093..12293
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CDO52_RS04360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CDO52_04350"
                     /product="hypothetical protein"
                     /protein_id="WP_017621322.1"
                     /transl_table=11
                     /translation="MCFPKQVPPVRRPELVNPNRMVDLAKAAQGEWAALGELSVFTTHL
                     NDPQAYTPPSYQEMQYSAAWW"
     gene            12401..14281
                     /locus_tag="CDO52_RS04365"
                     /old_locus_tag="CDO52_04355"
     CDS             12401..14281
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyanobactin: cyanobactin_synth"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012311.5"
                     /locus_tag="CDO52_RS04365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04355"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_152471862.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.9e-16, bitscore:
                     58.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="cyanobactin_synth (E-value: 2.7e-26,
                     bitscore: 90.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEGHRAAAGNAEIPEPSPSSVPEELFPADAVAGVKELWVHTRGE
                     PEVTIGVVESPPDMEHPSLAGSEITMVDSWWMPAVTPEDGAMEHGTYTASVLFGQPGSV
                     LEGLAPRCRGLICPALRDNSSVLDPLNAARAIEELTEAGADIVLFMAAHPAPADGNGTF
                     DLVRRAVEQASQAGVLVTAPAGNDYGRNPVAPALLPEVLAVGAHRADGTMYKFSNWGDG
                     YHGHGIAAPGGEVLGAAPGGGVKAQKGTCVAVSMATGAAALLLSLQRKAGLSADPLGVR
                     EALLRTARSCDPEIAHDDTGRCLNGKLDLPAAARMLVGEGVLSSNRTSGAGAAVPSSAS
                     AVRLCSPTTAAKPARSPAATPKCRKRMAAAGDETARSDTRITTFAERPELVQSGIERTP
                     PGPGFLQRSLADRWEVAKRLCGRFPQFGVAATRAVDGSVVGHGIGVPLALSASGRGHLP
                     GGGGQEMLAWALCDERRGVHPDTLGLLGMTIHPEHRGTGLSRSLLQALKEAARSAGLRE
                     VVTSVRPTAKHRRPAEPMAHYARRTHRDGLPCDPCLRVHAQAGGRITSVAPSALVVSGP
                     LAKWRQWTGLPFDAPGPVHVPLTLAPVRCDPAQDRAVYVEPHVWVRHALD"
     gene            complement(14393..14641)
                     /locus_tag="CDO52_RS04370"
                     /old_locus_tag="CDO52_04360"
     CDS             complement(14393..14641)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012610.5"
                     /locus_tag="CDO52_RS04370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04360"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_083920109.1"
                     /transl_table=11
                     /translation="MNADLDGPEPMYRQIAAVIAGRISDGTHEANRLVPSEAAVCEEFG
                     VSRRTARSAYQVLAEQGLVVTAPGKGTYVAPKADGNR"
     gene            complement(14728..14976)
                     /locus_tag="CDO52_RS04375"
                     /old_locus_tag="CDO52_04365"
     CDS             complement(14728..14976)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621320.1"
                     /locus_tag="CDO52_RS04375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04365"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_017621320.1"
                     /transl_table=11
                     /translation="MDIDHFDPTPIYKQVARVIRGRIKSGELKPRDRIPSESQMVAEYG
                     IARDTARQAVALLRSEGWVITLPQRGTFVALQPGTDA"
     gene            15147..15290
                     /locus_tag="CDO52_RS28025"
     CDS             15147..15290
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621319.1"
                     /locus_tag="CDO52_RS28025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_017621319.1"
                     /transl_table=11
                     /translation="MQTNRLSERSANRVRPYITVLEHQRAVQDRLFRWFAAQVARSSTE
                     VG"
     gene            15290..15526
                     /locus_tag="CDO52_RS04380"
                     /old_locus_tag="CDO52_04370"
     CDS             15290..15526
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621318.1"
                     /locus_tag="CDO52_RS04380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04370"
                     /product="hypothetical protein"
                     /protein_id="WP_017621318.1"
                     /transl_table=11
                     /translation="MNSDNDPLLRLLRERYGDQWAIRRTEHLWIAVTHDTEADHAPTIV
                     QPDMNVFLSDLENPPPRACCPRSLMSAEFFSAQ"
     gene            complement(15682..16137)
                     /locus_tag="CDO52_RS04385"
                     /old_locus_tag="CDO52_04375"
     CDS             complement(15682..16137)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621317.1"
                     /locus_tag="CDO52_RS04385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04375"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_017621317.1"
                     /transl_table=11
                     /translation="MEYSHNDTELLDQPIGYWSWAAHKAVVDHIRANLAELGVTQPQNW
                     ILDQVLSGRNGRTREEITEILEGYLDVGTTLDAEFDGLIEKGLIRVDDEEQLWGTAEGE
                     AVFRQCTERHAAMKKARNAGVTDADYITTLKVLQRMIHNVGGRAWHE"
     misc_feature    16208..16221
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: strong, score: 23.84"
                     /tool="antismash"
     gene            complement(16265..16864)
                     /locus_tag="CDO52_RS04390"
                     /old_locus_tag="CDO52_04380"
     CDS             complement(16265..16864)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017559330.1"
                     /locus_tag="CDO52_RS04390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04380"
                     /product="short chain dehydrogenase"
                     /protein_id="WP_026126324.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.4e-06, bitscore:
                     24.7, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILLIGAAGKLGAHVHATLADRGHDVVTVGRTSGDIRLDITDPV
                     QATELYDRAGHIDAVASAAGDVPYNTLTKLTADDYLSAFRGKALSQIELVRQGTKRIAE
                     RGSFTLITGALARDPIVSGSAAAMANGAVEAFVRSAAIEIAPQRVNAISPTVFTESLAD
                     YGDFFPGIPPVDLTQVAQAYVRSIEGAQTGQIYELD"
     gene            16935..17789
                     /locus_tag="CDO52_RS04395"
                     /old_locus_tag="CDO52_04385"
     CDS             16935..17789
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621315.1"
                     /locus_tag="CDO52_RS04395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04385"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_017621315.1"
                     /transl_table=11
                     /translation="MNVELRHFRALAAIGDEGTITGAAAALRISQPALSRTLSQLERGL
                     GTQLVERTTRNLHLTEAGRRLWEHAHRILAHVDDALAEVSAGPRPLRIGFAWAALGHHT
                     VPLLREWRRDHPDIPLQAQRLDDPEAALRCGDIDLAFLRTPTDDDEFYSLPLYQERRLV
                     ALSEDDPLATRPSLELADIADRTIAMCASAGTTSTELWSADRRPSTTIEVANVDEWLTV
                     IATGDAVGVTAEATGHSHPHPGVRYLPIADAPPITVCLVWPPYPVHSAAATFREHARRT
                     VET"
     misc_feature    17885..17900
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            17886..18218
                     /locus_tag="CDO52_RS04400"
                     /old_locus_tag="CDO52_04390"
     CDS             17886..18218
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621314.1"
                     /locus_tag="CDO52_RS04400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04390"
                     /product="putative quinol monooxygenase"
                     /protein_id="WP_017621314.1"
                     /transl_table=11
                     /translation="MIFITAKFRILPEYADSWPEIAREFTEATRSEPGCLWYDWSRSVE
                     DPNEYVLVEAFRDDEAGAAHVQSEHFKTAQKTLPPHLAETPKIVNTTIPQDDWSLLGEM
                     AVPPRD"
     gene            complement(18362..18829)
                     /locus_tag="CDO52_RS04405"
                     /old_locus_tag="CDO52_04395"
     CDS             complement(18362..18829)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621313.1"
                     /locus_tag="CDO52_RS04405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04395"
                     /product="DoxX family protein"
                     /protein_id="WP_017621313.1"
                     /transl_table=11
                     /translation="MAEARGLVNALRHALVVRDAPPAVLLIRLIAGAVFCSEGIQKFLY
                     PGDLGPGRFAAQTPLPAPEVFGYSAAVFEISCGLLLVVGLLTRLATLPLLTIMGGALLF
                     TKLPILMDEGFWRAAHEARTDSLLLFSLVFLLLVGAGRWSLDRRFFPRRES"
     gene            complement(18986..19351)
                     /locus_tag="CDO52_RS04410"
                     /old_locus_tag="CDO52_04400"
     CDS             complement(18986..19351)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621312.1"
                     /locus_tag="CDO52_RS04410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04400"
                     /product="DUF6463 family protein"
                     /protein_id="WP_017621312.1"
                     /transl_table=11
                     /translation="MISRSPGRWVQALAGLHFATGIILYRKPAGDMAADGVVSTVPDWG
                     DRATAFWFLALAPAMWTTGRLLRSAEENGDTRAQRTAGAALVATGATGAAMMPASGFWG
                     VAALGAWAWAKGRRASH"
     gene            19561..19914
                     /locus_tag="CDO52_RS04415"
                     /old_locus_tag="CDO52_04405"
     CDS             19561..19914
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621311.1"
                     /locus_tag="CDO52_RS04415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04405"
                     /product="YciI family protein"
                     /protein_id="WP_017621311.1"
                     /transl_table=11
                     /translation="MQHYMLTIHQPQGETPSPEVLEPIMRDLEAVNEELRAAGAWVFAG
                     GMHQPSTYTVLRPKDDEVITTDGPYAEGKEFIGGFTVIKAPDLDAALEWGRKFARAITL
                     PVEVRPMQYGSCG"
     gene            19911..21194
                     /locus_tag="CDO52_RS04420"
                     /old_locus_tag="CDO52_04410"
     CDS             19911..21194
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621310.1"
                     /locus_tag="CDO52_RS04420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04410"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_017621310.1"
                     /transl_table=11
                     /translation="MTSGSPEVSAAEIERVFREERGRAVAVLVRLLGDIDLAEEAVQDA
                     FAEAVQRWPSAGLPPSPAGWIITTARNRSIDRLRREASRKDRYAQAALLHAHDDAPSEE
                     GPVCDDRLRLIFTCCHPALAPHSRVALTLRLLGGLTTAEIAHAFLVPESTMAQRLVRAK
                     GKIRDARIPYRVPDESDLPDRLRGVLSVVYLIFNEGYAASSGDRLVREDLCAEAIRLGR
                     LLAELMPDEPEVLGLLALMLLTESRRAARTTPDGALVRLADQDRERWDRALIAEGQEIV
                     RACLRRDRPGPYQIQAAINAVHSDAATAAATDWSQILRLYDHLYALTPTPIVALNRAVA
                     VAEVEGPEAALSRVDALASDLDRHHLFHAVRADLLRRLGRSAEAVMAYEAALDRTQNAA
                     ERDFLRRRRADLDSARESDPRNGDARTT"
     gene            complement(21191..22483)
                     /locus_tag="CDO52_RS04425"
                     /old_locus_tag="CDO52_04415"
     CDS             complement(21191..22483)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621309.1"
                     /locus_tag="CDO52_RS04425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04415"
                     /product="ROK family transcriptional regulator"
                     /protein_id="WP_017621309.1"
                     /transl_table=11
                     /translation="MSSVNTGPTGFQAVREANLGVVLRAVRSLAPCSRAAIAAATGLNK
                     TTVSSLVADLISRGLVRETGESTQRRVGRPGVLLALDDSTIAAIGLEVNVDYLSVVAVD
                     LVEQELLTRHISFDARAAGPEACAHRIARATAEAMADPALAGRGVIGVSVAVPALIDAP
                     SGTVTRAPNLGWRDTPLRDRLTHLMAEARLPTAPILVDNDANLGAVAEFRSGHLTRTPD
                     LVYITGEVGIGAGVLTDGNLLRGSTGFAGEIGHIPLMEDGPECGCGRRGCLEAIAGIEP
                     ILRAAVPDRVPEGPLSGDGIAHLVDVAVERAEAGDATALDTLHTAGTWLGRGIATLVDI
                     VNPAAVVLGGYFVPMAPWLLPNCRAAVREIAIAPDAGGCRVEPSTLGLSAAARGGAMAM
                     IDALDSGRLPLPPARSAAPAATSGPGPNAPA"
     gene            complement(22891..23598)
                     /locus_tag="CDO52_RS04430"
                     /old_locus_tag="CDO52_04420"
     CDS             complement(22891..23598)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621308.1"
                     /locus_tag="CDO52_RS04430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_04420"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_152471861.1"
                     /transl_table=11
                     /translation="MTAHSATSASTPGAVPSSWPTSVDRTLPLRERKKLRTRRALAEAA
                     LTLFSEKGFDAVTLDELVDAVEVSKRTFFRNYASKEQVALAAQNELLDAYVIVVAREEL
                     HGPVFPALRDALTLAIRRMDDDWEDRFLRTRRLIYHTPALIDYSVVESMRVQRRLVQEL
                     EAKLGIDRHEDVRLRLVGEFAISAWRCGTKNWLADQRGTGRRDRGGRAALIASVEEAFD
                     AIPGTVAMSAPAP"
     misc_feature    23809..23825
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 21.12"
                     /tool="antismash"
ORIGIN
        1 cgctacgccg agtgggtcgg cggggttctc cacggcgacc tcggcttctc ctacatgacc
       61 ggccgtcccg tggccgacgc gatcgccgac gcccttccct ggacgctcct gctggccgcc
      121 gtggctaccg tcttcagcct gatcggagcg atcgcgatcg gcctggtcgc cggtctcacc
      181 cggagcaccg cgctgcgccg cgcgatccag ctcgccatgt tcgcactggg cggtatgccc
      241 gggttcgtcg gtgcgctgct gctcttgttc gtgttctccg tctggctggg ctggttcccc
      301 tcgggcggac tggggcagcc ggggcagccg ctcacgccgg ccatcgtggc gtcctcggtg
      361 acgctgcccg ccctggcact gacgttcggg caccacttcg gcgtctacgt ccgactggtg
      421 gagacgggcg tcgcgcgggt gcgcgggtcc acacacgtcc tcaacgccga ggcgcgcggc
      481 ctgccgccat ggacggtgcg gacccggcac atcctccggc cggggctggt tccgttcgcc
      541 gctcggttcg gcaccggcgt cgcccaactg ctggccggcg cttacgcgat cgaactcatc
      601 tacgcgtggc ccggcatggg gcggctggca ctggaagcgg cgcagacgca ggactacccg
      661 gtgctgctcg ccgttgtact gatcaccggt gcgatcgtgg tcaccgccaa cctcatcggc
      721 gagatcgcca ccgcgcgact ggaccccagg atccgactca cgcgtgatga tcctcgggcg
      781 cggtcagggg cgtcgtagaa cgggtcccgc ctcctgctcc cgcccctgcg cgtgatcagg
      841 cagctcccgt cgacgaggcg gcgccaggta gagcccgggg taacgcatca cccgcacgga
      901 accgcgcacg acggcctcct tccaacgggc ggcggttcgg ccggtcagga tggcgcggtg
      961 gggggagtcg tcaggacgca cgaactggat gagaccgtcc cggcggccga ggctgatgtt
     1021 ctgcgcggcg taccggaaac ggaacggatg cggatcacgc cctgtgatgc gggcggcgat
     1081 cgcatcggcg gcctgccacc ccatcggaac accggtccca caggccatgc ggagctgctg
     1141 ggacgcgagt cgacctggac cgcgggccag ggccgcgtcg ccgactgcgt acacattcgg
     1201 gtgggagtgc gaacgcatcg tctggtccac gaggatgcgt ccatcgtgat cgacggcgag
     1261 tccggactcg cgggcaaggg cggggacccg gaaacccgtg gtccagacgg tggcgtcgag
     1321 cggcaccgcg tcgccccgcg tcgtcatcag gcggtcctgt tggacctccg tgacggggga
     1381 gtccgcccga acatcgatgt ccaaccgccg gaacacgcgg cggagatgcc gctgagcggc
     1441 gagggacagg ccgtctcccg gcgcgtcggt ggacagcagc cgtacgcgga gacgtggata
     1501 ggtctcggcc agttcggtcg cggcctcgat gccggtcaat ccggcgccca ccaccccgag
     1561 gacgcctccg gcggcgccga ggtccgctgc ccggtgatga agtgcggcag cgccctcggt
     1621 gtcggagacg ctgaacgcgt gttctgcgac gcccggaacg acgtcgagat cggccatgct
     1681 gccgagcgcg tacacgagcg tgtcgtattc gaggctcagc tcgtctcggg attcgccggt
     1741 cacgcgcacg tgccgccgct ccgggtcgac ggaggccacc cgtccgacga tgagctgaac
     1801 accggttccg tccagcagtt ttcgcagggg gaggtcggca agccgctgac cggtggcgag
     1861 ctggtggagc cgcacgcgtt ccacgaaatg gggattcgcg ttgaccaggg tcacgcgtgc
     1921 gtcatgcggg tggagtcggc gggctagccg ggcagtggtc gtgagacccg cgtaaccggc
     1981 gcccagtacg aggatgcggt gcgtcactga cgtccccttc cctttccctt ttcccttcgg
     2041 aagccctgga cggcgaggcg gatgtgcggt gcttggcgac accgcccgcc gtgatggcat
     2101 ctcctgaacc ggggagagga ccgatccatg acaggaactg ggtgtgtccc ccgtcacacg
     2161 tgcgcgggta gacgggtggg gagggggaga gaccagcctt tcagcgaggc gtggtgggcc
     2221 agagaagcac gcccgcgtgg gaacgggaca gctgagcgcc gatgaacgca agcttgtcgg
     2281 ggttgacgat ggtgcggatg gctgcgatgc ggtcgtcgtg aagctcaagg accgccacag
     2341 caagcggtcc gctgtcgacc gtgaccagga gcgccggttc tccgttgacc tccgcagcgc
     2401 aaatctccag gccgggcccg aagcgttctt ccacgatggc gtcgatctgt cggaacagtc
     2461 cgtggaggta acgcgccacc ctggtgctgc cgaagatggg gcgccgtgcg gccccgatct
     2521 tgccaccgcc atccgcccac gcggtgacat cgtcggccag cagtcgttca aggccggtga
     2581 ggtcaccgct gtgtgcggcc gcgaagaaca gctcggcgat ccggttccgc tgctcgtggg
     2641 gtgtctcgga gaccggccga tggccctgct cgtcatgcag cttctgcctg gcccggcgat
     2701 tgagctgctg gcagttcgcc tcgctgagat ccaggacctc agcgatctca cggtggcggt
     2761 acgcgaatgc ttcgcgaagt acgaagaccg cccgttcggc gggcgtgagc cgttcgagca
     2821 ggaccagcaa cgccatggat acggactcac gctgctcgac ggtttccagg ggaccgagcg
     2881 acgagtctgg ggttagcact ggctcaggaa gccacggccc cacgtacgcc tcccgacgcg
     2941 cgcgggcagc ggtcagacgg ttgagacaga ggttggtaag gaccttggtc agccaggccg
     3001 caggcgtggt gatgaggttg cgatccgtgt cgctccaacg caggtacgtg tcctgcacgg
     3061 cgtcctcggc ctcggtcgca gagccgagaa gacgataggc gacagcgaag agccgaggcc
     3121 ggtgggactc gaactccgaa acgtgctctc cgtccaacgg tgctgacaca tcgccgagcc
     3181 tagatgcagg actgacgcgg gggtgtcccg ggtcacgcct ccccaagttg gtgttcccgg
     3241 agtagagggc tatagttgtc cgagtcgcct tgaagcagcc ggttcgcccg gccctcgggg
     3301 cggcggtctt ctctccggcc gcaccttggt cttgtccgat ggtggtggcc gcgtctgcag
     3361 ggtccgaagc tcagagtctg gctggcatac atcagtgtgc cgggcgggtt ttgctgtggg
     3421 gattctgtgc ggcgattttt cagggaagct ttcacgaaaa tccgccggtt tggcgggttg
     3481 cggaagccct gataaagtgg agacacaaca aagcggaacg caccgcctca acagaaaagc
     3541 cagaccaggc aaatgacagg tcggctcgta tgggatgagc ggttgtttct tgagaactca
     3601 acagcgcgtg tttgtttttc tttcagccaa gtttgttttg gcccttttga gcacacggaa
     3661 cccttggtgg ttgcgggtgc tcgggttcct ttgattggcc atgatgcgag tcatggtcgg
     3721 tcagggttat ctcttccagg tttacccgcc atgcttcggc acggttgggt tgtttggcct
     3781 ttgatggaga gtttgatcct ggctcaggac gaacgctggc ggcgtgctta acacatgcaa
     3841 gtcgagcggt aaggcccttc ggggtacacg agcggcgaac gggtgagtaa cacgtgagca
     3901 acctgcccct gactctggat aagccgtgga aacgcggtct aataccggat acgacaccct
     3961 gccgcatggc ggggtgtgga aagtacttgt cggttgggga tgggctcgcg gcctatcagc
     4021 ttgttggtgg ggtgaaggcc taccaaggcg attacgggta gccggcctga gagggcgacc
     4081 ggccacactg ggactgagac acggcccaga ctcctgcggg aggcagcagt ggggaatctt
     4141 gcgcaatggg cgaaagcctg acgcagcgac gccgcgtggg ggatgacggc cttcgggttg
     4201 taaacctctt ttaccactca cgcaggcctc aagttttctt ggggttgacg gtaggtgggg
     4261 aataaggacc ggctaactac gtgccagcag ccgcggtaat acgtagggtc cgagcgttgt
     4321 ccggaattat tgggcgtaaa gagctcgtag gcggtgtgtc gcgtctgctg tgaaaggctg
     4381 gggcttaacc ctggttttgc agtggatacg ggcatgctag aggtaggtag gggagactgg
     4441 aattcctggt gtagcggtga aatgcgcaga tatcaggagg aacaccggtg gcgaaggcgg
     4501 gtctctgggc cttacctgac gctgaggagc gaaagcgtgg gagcgaacag gattagatac
     4561 cctggtagtc cacgccgtaa acgttgggcg ctaggtgtgg gggctttcca cggttcccgt
     4621 gccgtagcta acgcattaag cgccccgcct ggggagtacg gccgcaaggc taaaactcaa
     4681 aggaattgac gggggcccgc acaagcggcg gagcatgttg cttaattcga cgcaacgcga
     4741 agaaccttac caaggtttga catcaccggt aaaccatcgg agacggtggg tccttttggg
     4801 atcggtgaca ggtggtgcat ggctgtcgtc agctcgtgtc gtgagatgtt gggttaagtc
     4861 ccgcaacgag cgcaaccctt gttccatgtt gccagcacgt gatggtgggg actcatggga
     4921 gactgccggg gtcaactcgg aggaaggtgg ggatgacgtc aagtcatcat gccccttatg
     4981 tcttgggctg caaacatgct acaatggccg gtacagtggg cgtgcgatgc cgtgaggtgg
     5041 agcgaatccc taaaagccgg tctcagttcg gattggggtc tgcaactcga ccccatgaag
     5101 gtggagtcgc tagtaatcgc ggatcagcag tgccgcggtg aatacgttcc cgggccttgt
     5161 acacaccgcc cgtcacgtca tgaaagtcgg caacacccga aacctgcggc ctaaccagct
     5221 tgctgggggg agtgggtgaa ggtggggctg gcgattggga cgaagtcgta acaaggtagc
     5281 cgtaccggaa ggtgcggctg gatcacctcc tttctaagga gtcttatggg ctggtcgtga
     5341 catcggctgt tgtggtcggt ggcggtcggc ggactcgaaa gtggacccag gagcagggtt
     5401 taggcctcgg tctggacctg gcgctgctgg gatggctgaa ctgagagacg aacttctgca
     5461 cctcgtcctg gaagacgggg tgcgggcgcg ctgttgggtg tctgaggatg caaccgctgg
     5521 ttgtgttcct gcgtgccacc ctgacgaaga cccgcgtggt cgcctcgtct cgctggtgct
     5581 ggtcggctgt ttctcggttg gctggtggtg cagcgggtga ggggtttgat cgcagtgtgc
     5641 ggtgttgtgg ttgggtgtgt ggctggtgtt ttgattcgtg gatagtgtgc gcgagcatct
     5701 tgtatctgtg gtggccaagt tagtgtggca tacggtggat gccttggcac caggcgccga
     5761 tgaaggacgt gggaggccgc gataggccgc ggggagctgt caaccgagct gtgatccgtg
     5821 ggtgtccgaa tgggggaacc tagcccgagt tgtgtcgggt tgccgccgtc tgaatgtata
     5881 gggcggttgg tggtgacgcg gggaagtgaa acatctcagt acccgtagga agagaaaaca
     5941 acagtgattc cctgagtagt ggtgagcgaa aggggatggt ggctaaaccg tgcgcgtgtg
     6001 atagacggca gttgttgcgt gtgcggggtt gtgggatgtg catgttcggg cctgccggcc
     6061 cggagcgctg atggttgttc tagccgaagc cgttgggaag cggtaccgga gtgggtgaga
     6121 gtcccgtagg tgaaggaaca gcctaggcgt ttgcattctc ccgagtagcg cggagcccga
     6181 ggaattccgt gtgaatctgg caggaccacc tgtcaagcct gaatacgtcc tggtgaccga
     6241 tagtgcacaa gtaccgtgag ggaaaggtga aaagtgcccc ggtgaggggt cgtgaaatag
     6301 tacctgaaac cgtgtgctgt caagccgtca gagctcctgc ttgcaggggt gatggcgtgc
     6361 cttttgaaga atgagcctgc gagttatggt gtgtggcgag gttaacccgg gtggggtagc
     6421 cgtagcgaaa gcgagtctga agagggcgaa catagtcgca tgctgtagac ccgaagcggg
     6481 gtgatctacc catggccagg gtgaagcggc tgtaagaggt cgtggaggcc cgaacccacc
     6541 agggttgaaa acctggggga tgagctgtgg gtaggggtga aaggccaatc aaactccgtg
     6601 atagctggtt ctccccgaaa tgcatttagg tgcagcgtcg tgtgttgctt gccggaggta
     6661 gagcgactgg ttggctgatg ggcccgacaa ggttactgag gtcagctaaa ctccgaatgc
     6721 cggtttaagt tatagcgcgg cagtgagact gcgggggata agcttcgtag tcgagaggga
     6781 aacagcccag atcatcagct aaggccccta agcgtgtgct aagtgggaaa ggttgtggag
     6841 ttgctgagac aaccaggagg ttggcttaga agcagccatc ctttaaagag tgcgtaatag
     6901 ctcactggtc aagtgattct gcgccgataa tgtagcgggg ctgaagcaca ccgccgaagc
     6961 tgtgaagccc gggcttaggt ccgggttggt aggggagcgt cgtgcgtccg gtgaagcctc
     7021 gggtgaccta ggggtggagg gtgtgcgagt gagaatgcag gcatgagtag cgaaacacac
     7081 gtgagaaacg tgtgcgccga ttgactaagg gttcctgggc aggttaatcc gcccagggtg
     7141 agtcggggcc taaggcgagg ccgacaggcg tagtcgatgg ataacgggtt gatattcccg
     7201 tacccgttca cacgcgccca gtaccgagtc ctttgatgct aaccaccact gaagcggtgg
     7261 tgtgccttcg ggtgcgctgt cgtggaggcg tgggacccag gagggtagta ggtaagtgat
     7321 gggtgacgca ggagggtagc tctaccgggc ggtggttgtc ccggataagc gtgtagcccg
     7381 agagataggc aaatccgtct ctcgttacat gggtgaggcg tgatgtcgag ccgtttgtgg
     7441 tgaagtgagt gatcccgtgc tgtcgagaaa agcctctagc gagtgtgtgg gcggcccgta
     7501 cccgaaaccg acgcaggtgg tctggtagag aataccgagg cgttcgggtg aaccatggtt
     7561 aaggaactcg gcaaattgtc ccgtaacttt gggagaaggg gagccctgtc tggtgatggc
     7621 ctttgcggtc tgagctgggt ggggtcgcag ataccagggg gaagcgactg tttattaaaa
     7681 acacaggtcc gtgcgaagtc gtaagacgcg gtatacggac tgacgcctgc ccggtgctgg
     7741 aacgttaaga ggaccggtta gacgcgttta cgtgtcgagg ctgggaatct aagcgccagt
     7801 aaacggcggt ggtaactata accatcctaa ggtagcgaaa ttccttgtcg ggtaagttcc
     7861 gacctgcacg aatggcgtaa cgacttcccc gctgtctcaa ccatgggccc ggtgaaattg
     7921 cactacgagt aaagatgctc gtttcgcgca gcaggacgga aagaccccgg accttcacta
     7981 tagcttgaca ttggtgtttg ggatggtttg tgtaggatag gtgggagccg gtgaagccgc
     8041 cacgctagtg gtggtggagg cgttggtgaa ataccactct ggctgtttcg ggcatctaac
     8101 ccgcacccgt gatccgggtg ggggacagtg tctggtgggt agtttaactg ggcggttgcc
     8161 tcctaaaggg taacggaggc gcccaaaggt tccctcggcc tggttggcaa tcaggtggtg
     8221 agtgtaagtg cacaagggag cttgactgtg agacggacgt gtcgagcagg tgcgaaagca
     8281 gggactagtg atccggcacc ggcgtgtgga agcggtgtcg ctcaacggct aaaaggtacc
     8341 ccggggataa caggctgatc ttccccaaga gtccgtatcg acgggatggt ttggcacctc
     8401 gatgtcggct cgtcgcatcc tggggctgga gttggtccca agggttgggc tgttcgccca
     8461 ttaaagcggc acgcgagctg ggtttagaac gtcgtgagac agttcggtcc ctatccgctg
     8521 tgcgcgttgg agacttgaga agggctgtcc ctagtacgag aggaccggga cggacgaacc
     8581 tctggtgtgc cagttgttcc gccaggagca tggctggttg gctacgttcg ggagggataa
     8641 ccgctgaaag catctaagtg ggaagcttgc ttcgagatga ggtctcctgc ccctaagagg
     8701 ggtaaggctc ccagtagacg actgggttga taggccgggt gtggaagcct tgtgaggggt
     8761 ggagctgacc ggtactaatc ggccgagggc ttgtccaccg cagatggctg ggtgctcgcg
     8821 cacactattt catcactctt gaaggtaggg gtggtggagc gtgatgatcg cacacgaatc
     8881 gtttttgttc tttttcatat ggttgccgct cgttgcggcc cttggttttc ccgacacgga
     8941 tcgtgtggtt cgtggtttgg ggttagggtt gcggtggttt ttgcgagggg gtcacacccg
     9001 gtctcatttc gaacccggtc gttaagttcc tcagcgccga tggtactgcc tccatggtgg
     9061 gggtgggaga gtaggacgcc gccgcgcatt tcttgtggag gagggttgcc cctgtggggg
     9121 tggccctcct ccttttttat tgcccgggtt tgtgaacatg tgaatcaacg gcgtgctgtg
     9181 ggggtggcgt tcccctgcct cctggcaccg cttcactcta ggttgacgtt gcaagagccc
     9241 agttcagtcc gtgtctgtgc gtccgcatcg tggttggcga ggcagtcaag gatcgcgtcg
     9301 gctgtgggtc aattcggatg accaaaatca acatatgacg aatgcccaaa ttgactggct
     9361 cagtgtgatc aaagaatcgc gcttgagtcg gacatcgagc gatttgtcgt gtcgtcccat
     9421 taccgactct gagagtcatc ctgtcacggg tggtttgaga atcagacggc ccggttatgg
     9481 tcgctcgcgc cggtggagtg tcgcgttttc gattaacaac cactggcgtt ggatgctcat
     9541 tgaaggaatg cccaagcgat tccacgtttt ctttctagtg cgtccgaagt taatcgaagt
     9601 gactctggcg atggtgacga gtagtcacct cgatccaacc tggccaccac ggggcgtaag
     9661 gcgcacctgt ggggacaaag aggaggtagg agaatgcagg aaaagatgca ccagcctggg
     9721 atgccgttgc tggctgaccc agtggaacgc aagctcaaca ccacggccgc gtcggccgcc
     9781 gacggtgtcg accagtcaat cttcggcggg atcacttgga aggacattcc gttcgctggc
     9841 gacagcgacg agtagtctgc tgcgatccgt tgtggacttt tcggcctcgc ccggcttgcg
     9901 aggtcgatcg ggccatgaat gccagcgcgg atatgtgatt tttccgcata gtgcggtctg
     9961 accttggtat gagcacacga gttctgagga gtcgtaatta atggggaagc tgtcaatcat
    10021 tcccgggctc tccgagctgt ggcggctgac caagggtgac gaccgtgtag gggtggccgt
    10081 ggtcgacggc agggtcggtg ccggccaccc cgccttcgct gggagtgggc tggcctccgt
    10141 ggagggtgtg tggcccagcg acggtgcgac gggtgcgaag gcggcccatg gcacgtccgt
    10201 ggccggagtt ctcttcggtc aacacgacgg ccccgtccca ggcgtggcgc cagggtgccg
    10261 gaaggtgagc gttccggcgt tctcggaccg gtgggcgcgc acgtcacagc tggaccttgc
    10321 gcgcggaatc gagctggcgc tggacgaagg cgtgcacgtc atcaacatca gcggcggaca
    10381 gctcgcctcg gccgaggaag cagaggaccc actggcgcgg gcggtgcgcc ggtgcaagga
    10441 gagcaacgtc ctggtcgtgg cagccgccgg gaacgacggc tgcttctgcg atcacgtgcc
    10501 cgcggctctg ccctcggtat tggcggttgg cgcactggac gacgagggcc gtccgctgcc
    10561 cagcagcaat tggggtccgg ggaacactcg ccagggcatt ctcgccccag gccagaacat
    10621 cccggtgcca gttcccggcg gaggcgtggc tctgcagacc gggaccagcc tggccgcgcc
    10681 ggtcgtgtcg ggcgtggccg cccttctgct cagcttgcag ctacgcgacg gtcgtgaacc
    10741 cgacccgcgg gccataggcg agcttctgat gaccactgct gatccgtgcg acctcggcga
    10801 cgccgatgcc tgcgcacgtt ttctgaacgg caaactcaac atcacgaaag cggtaaccac
    10861 tgtgacctcg aacgagacag acgtgtccgt ggctcactcg caagctgagc cggtgtcccc
    10921 gatccccgag accgcgaccg gcagacccga gcaggcggtg cccagctgtg actgcgggtg
    10981 tgaccaagca ccggccgcag ccgcgacggt cccgactgcc caggctgccc tgcaagctcc
    11041 gacggatcct gcggcggctc ctgcgacaac ccctgcggcg gggtcagcgg cggtgaccct
    11101 gtcctcaccg gctccggccc ccgtgccatc tcccgcgccc gcgccgcccc cggctcctac
    11161 gccaccgcca caggccacgt caacggtgac gacgtcgtca gacgacccag cgcgcgtgcc
    11221 ggcccagcgt ctggcgtatg cgcagggcgt actgggatac gacttcgcta ctgaggcgcg
    11281 tcgtgacagc ttcaagcagc tcatggcgcc cgtcgaggtt ggcggtgcgc acgtccccgc
    11341 caacccgtac gaccccaacc acatggtcgc tcacctcagg gagaatccct ctgagtcatc
    11401 cgcgctgatc tggacgctca atctcgacct gacaccgatt tacgccatcg aacccaacgg
    11461 cggctacaca gtcggcgtgt acgagcgtct ggtggatttc ctatcccgtc agcttgagtg
    11521 tgatgacggg gcgaacttcg tcgaccgcgt ctcgatcccc ggtaaattgc ccggccgtac
    11581 ggtcaagctg ttctcgggtc aggaagtgcc cgtcgtggag gtcgaactca agcgcggcct
    11641 gtacgggtgg tcggtcacga gcctggccaa cgcggtcgcc gaggctggag cggctggggc
    11701 caagaagggc aacccgtctg cggacacact gcgtgcggcc gtcgcggagt tcctcacccg
    11761 cgtctactac gatctccgca atttcggggc gacctcgcgc gaccgcgcgc tgaacttcgc
    11821 cgcgaccaac gcggttcagg cccgcgacac tctggctcag gcactgagcc aaggtctggc
    11881 cctgcaggac atcgacgtcg agaagagccc gttcgcccgc cccgacagcg actgctggga
    11941 tgtgaagctg cgcttcttcg accccgagaa cagccgccgc gccaagcggg tgtaccgctt
    12001 caccgtcgac gtcaaggacg tcatgccggt gaccgtcggc gacatccgaa gctggcctga
    12061 gagctgaccc gacacccgca aggagggacg cgatgtgctt tcccaaacag gtgccgccgg
    12121 tgcgccgtcc tgagctggtg aacccgaacc gcatggtcga tctggcgaag gcggcccagg
    12181 gcgagtgggc cgccctgggc gagctgtcgg tgttcaccac gcacctcaac gacccgcagg
    12241 cctacactcc gccgagctat caggagatgc agtactcggc ggcctggtgg tagcccctcg
    12301 aacgtgatcc aggagttggt gcaccttgtg cgaacagacg tcccagtcgc ggcaacgtga
    12361 gccactgccg gatggactaa cggcagacgc ggtgggggcc gtgcccgagg ggcaccgcgc
    12421 cgcggccggg aacgccgaga ttccggagcc atctccatct tcggttccag aggagctgtt
    12481 tccggccgat gcggtcgccg gcgtcaagga gctgtgggta cacacccgcg gcgagccgga
    12541 ggtgacgatc ggcgttgtcg agagccctcc ggacatggag caccccagtc tggcgggctc
    12601 cgagatcacc atggtcgact cgtggtggat gcctgcggtc actccggaag acggcgcgat
    12661 ggagcacggg acctatacgg ccagtgtgct gttcggtcag ccgggcagcg tactggaggg
    12721 tcttgcacct cgttgccggg ggctcatttg tccagcactg cgcgacaact cgtcggtgct
    12781 cgacccgctc aatgcggcgc gcgcgatcga ggagctgacc gaggcagggg ccgacatcgt
    12841 cctgttcatg gcggcacacc cggcgcccgc cgatggcaac ggcacgttcg acctggtccg
    12901 acgcgctgtt gagcaggcga gccaggcagg tgtcctcgtc accgcgcccg cgggcaacga
    12961 ctacggtcgc aatcccgtcg ccccggcgct gctgcccgag gtgctggccg tcggtgccca
    13021 ccgcgccgac ggcacgatgt acaagttcag caattggggg gatggctatc acgggcacgg
    13081 catcgccgca ccgggcgggg aggtgctcgg cgccgctcct gggggagggg tcaaggcaca
    13141 gaaaggcaca tgcgtggccg tgtccatggc gaccggcgcc gcggccctgc tgctcagcct
    13201 ccagaggaag gcggggctgt ccgccgatcc gctcggggtg cgagaggcgt tgctgcgcac
    13261 ggcccgctcc tgcgatcccg aaatcgccca tgacgacact gggcgctgtc tcaacggcaa
    13321 gctcgacctg cccgcagctg ctcggatgct ggtaggcgaa ggcgtgctca gcagtaaccg
    13381 gacctcgggc gcgggcgcgg ctgtgccgtc gtctgcttcg gcggtgcgac tctgcagccc
    13441 gacaacggcg gccaagcccg cgcgttcacc tgcggcgact ccgaagtgcc gtaagcgaat
    13501 ggccgcggct ggcgatgaga cggcgcggtc tgacacgagg atcaccacgt tcgccgagcg
    13561 gcccgagctg gtgcagtccg gcatcgaacg cacgcctccg gggcccgggt ttctccagcg
    13621 ctccctcgcc gaccgatggg aggtggcgaa acgcctctgt gggcgtttcc cgcagttcgg
    13681 cgtggccgcg acgagagcgg tcgacggctc ggttgtggga catggcatcg gcgtgccgct
    13741 cgcgctttcc gcttccggtc gcggtcacct gcccggcggg ggtggccagg agatgctggc
    13801 ctgggcactg tgcgatgagc gacggggcgt ccaccccgac actctggggc tccttggcat
    13861 gaccatccac cccgagcatc gtggcacggg cctgagcagg tccttgctgc aggccctgaa
    13921 ggaggcggcg cggtcagccg gtctgaggga ggtggtcacg tcggtgcggc caaccgcgaa
    13981 gcatcgccgc ccggcggagc cgatggccca ctacgcccga aggacccacc gtgacggcct
    14041 gccctgcgac ccctgcctgc gcgtccatgc ccaggcgggt gggcgaatca cgtcggtggc
    14101 tccgtctgcg ctggtggtgt ccggccccct ggccaagtgg cggcaatgga cggggttgcc
    14161 cttcgacgcc cctggcccag tgcacgtgcc ccttacgctg gctccggtgc gctgcgaccc
    14221 tgcccaggac cgtgctgtct acgtcgaacc gcacgtctgg gtgcgacacg cgttggactg
    14281 aagtggcgca gagcaaggcg gaagatgtcg atggctacct gatcgaggtg ccagaagacc
    14341 gggggaggtc ccgtccgagc tgcagcaggt gtgccgttga cagtgactgg ccctatctgt
    14401 tgccgtccgc ctttggagcg acataggtcc ccttgcctgg agctgtgacc acaagccctt
    14461 gttcggcgag aacctggtat gccgaccgtg cggttcggcg cgagaccccg aactcttcac
    14521 acacggctgc ttcggatggg acaagccggt tcgcctcatg ggtcccgtcg gagatccgac
    14581 ctgcgatgac agcagcgatc tgccgataca tcggttcggg tccgtcaagg tcggcattca
    14641 tgattaacga ccctagggat tcgcgatgat tctggtgcgc ttttggttaa ccgccctctg
    14701 cgacaagcgc acctgacagg ggtagggcta cgcgtcggtg ccgggttgca gcgcgacgaa
    14761 ggttcctcgc tgaggcagcg tgatcaccca tccctctgag cgcaggaggg cgaccgcctg
    14821 tcgcgcggtg tctctcgcga tgccgtactc agcgaccatc tgagactcgg atggaatccg
    14881 atctctcggc ttgagctcgc cggacttgat ccgcccgcgg ataactcgcg ccacctgctt
    14941 gtagatgggc gtcgggtcga agtgatcgat gtccatgtct aggacgttag gtacgtaggc
    15001 catgctgcgc atatggccta cgtcgccaac gtcctagaca tggtagacaa gttccggcta
    15061 tgatcaaagg tccacagcaa caaaagaccc cggcgaggtg cgaactcccg gggcgtggcc
    15121 accagctaca agggagctga tgacagatgc agactaaccg tctgtcggag cggtccgcga
    15181 accgagtccg tccctacatc accgtgctgg aacaccagcg cgccgtccag gaccgcctct
    15241 tccggtggtt cgccgcgcag gtcgcccgct cctccacgga ggtgggctga tgaacagcga
    15301 caacgacccg ttgctgcggc tactgcggga gcgctacggg gaccagtggg cgatccggcg
    15361 caccgagcac ctgtggatcg cggtcactca cgacaccgag gccgaccacg cgccgaccat
    15421 cgtgcagccc gacatgaacg tcttcctctc cgacttggag aacccgccgc cgcgcgcgtg
    15481 ctgtccccgg tcactgatgt cggccgagtt cttctctgcc cagtaggacc aggtcgacga
    15541 cggcgtgtgg cgcaacaaca aaccgcccga gggctgaccc ccggccctcc gcggtcgatc
    15601 agccaataga gccccacccc gcctggtgga cgggtggggc tctcgctgtt gagggctggg
    15661 gctctggggt gccgaccggt gctactcgtg ccaggccctg cctccgacgt tgtggatcat
    15721 ccgctgcagc accttgagcg tggtgatgta gtcagcgtcc gtcacgcccg cgttccgcgc
    15781 cttcttcatg gccgcatggc gctccgtgca ctgtcggaag acggcttctc cctcagcggt
    15841 cccccacagc tgctcctcat cgtcgaccct gatcagcccc ttctcgatga gtccgtcgaa
    15901 ctccgcatcg agcgtggtcc ccacatccag gtagccctcc aggatctccg tgatctcctc
    15961 gcgggtccgg ccgttccttc cgctgagcac ctggtcgagg atccagtttt ggggctgggt
    16021 gacaccgagc tccgcgagat tggcgcggat gtggtcgacg accgccttgt gtgccgccca
    16081 gctccagtag ccgatcggct gatcgagaag ctcggtgtcg ttgtgcgagt actccattgt
    16141 cctgtcctca ccatctggcg atcccggctg gtgaggatga acatagaagc tcaattaagg
    16201 ttcaggtcaa acgcctgttt ccgcgtcgtg gacgggaaga tcattgccca cctggcgggg
    16261 gtggctaatc gagttcgtaa atctgtccgg tctgagcgcc ctcgatggag cgcacgtagg
    16321 cctgggccac ctgggtgaga tccaccggcg ggataccggg gaagaagtcg ccgtagtccg
    16381 cgagggactc ggtgaagacg gtggggctga tggcgttgac gcgctgcggt gcgatctcga
    16441 tcgccgctga ccggacgaag gcttccacgg cgccattggc catggccgct gcgctgccgc
    16501 tgacgatggg atcgcgggcc agagccccgg tgatcagggt gaacgagccc cgctcggcaa
    16561 tgcgtttcgt gccctggcgg accagttcga tctggctgag cgccttaccg cggaaggccg
    16621 agagatagtc gtcggcggtc agcttcgtga gcgtgttgta cggcacgtcc ccagccgcgc
    16681 tggccaccgc atcgatgtgt ccggcgcggt cgtacagctc ggtggcctga acagggtcgg
    16741 tgatgtcgag acgaatgtcc ccgctggtgc ggcccactgt gacgacgtcg tggccgcggt
    16801 cggcgagagt ggcgtgcacg tgggcgccaa gcttgcctgc cgccccgatc agcagaattc
    16861 tcatgccagc gacggtaggc acggggcagg cgacgaggga aataccgtct gagttgcggt
    16921 tatgctcatg ggttatgaat gtggaactgc ggcatttccg cgcgctggcg gccatcgggg
    16981 acgagggcac catcaccggt gccgcggctg ccctgcgcat cagccagccc gcgctttcgc
    17041 ggacactgtc gcagctggag cgcggcctgg gcacgcagct cgtcgagcgc accacccgca
    17101 atctccacct caccgaggcg ggtcggcggc tgtgggaaca cgcgcaccgc atccttgccc
    17161 acgtcgacga cgccctggcc gaggtgagcg ccgggccgcg accgctccgc atcggcttcg
    17221 cctgggcggc tctggggcac cacaccgttc cgctgctgcg cgagtggcgt cgggaccacc
    17281 ccgacatccc cctccaggcg cagcgactag acgaccccga ggccgcgctg cgctgcggcg
    17341 acatcgacct cgcttttctg cgcacaccga ccgatgacga cgagttctac tccttgcccc
    17401 tctaccagga gcggcgcttg gtggcactga gcgaggacga tcctctggcg acccgaccct
    17461 ccctggaact ggccgacatc gccgatcgga ccatcgccat gtgtgcctcg gccgggacga
    17521 ccagcaccga gctgtggtcc gccgaccggc gcccctccac caccatcgag gtggccaatg
    17581 tcgacgagtg gctcaccgtg atcgccactg gggacgccgt cggcgtgacc gcggaggcca
    17641 ccggacacag ccatccccac cctggggtgc gctacctccc gatcgccgat gctccaccga
    17701 tcactgtctg cctggtttgg ccgccctatc cagtgcactc cgcggccgcg accttccggg
    17761 aacatgcccg tcgcacggtg gagacttagg tgacacgtct cgctctatga gatggcctgc
    17821 ttgcacaggg caccctttta gcatcgagag tggttccgat cggggccgtg ttgatgagga
    17881 gtcccatgat tttcattacc gccaagttcc gcatcctgcc cgagtacgcg gacagctggc
    17941 cggaaatcgc ccgcgagttc accgaggcga cgcgcagcga gccggggtgc ctttggtacg
    18001 actggtcgcg cagcgtcgaa gacccgaacg agtatgtcct ggtcgaggcg ttccgtgatg
    18061 acgaggcggg tgccgcccac gtgcagtccg agcacttcaa gaccgcgcag aagacgctgc
    18121 cgccgcacct cgccgagacg ccgaagatcg tcaacacgac gatcccgcag gacgactggt
    18181 ccctgctcgg cgagatggcc gtgccgccgc gggactgagc gaccgagcac atcgtccgct
    18241 gatctcagtc ggcgtcgagc tctgagcccc gcttgccgta gcggggttca gagctcagag
    18301 caggccgcag acggagtccg aggctgaggc ccggttccga tgcggtggga ctgccgcggg
    18361 gttaggactc gcggcgcgga aagaacctgc ggtccagcga ccagcgtccc gcccccacga
    18421 gcagcaggaa caccaggctg aacagcagaa gcgaatcagt gcgcgcctcg tgggcggccc
    18481 tccagaagcc ctcgtccatc aggatgggca gcttggtgaa gagcagcgcc ccacccatga
    18541 tggtgagtag tggcagcgtg gccagtcggg tgaggagccc gacgaccaac agcagcccgc
    18601 agctgatctc gaacaccgcg gcgctgtaac cgaagacctc tggtgcgggg agcggggtct
    18661 gcgcggcgaa gcggcccggg cccaggtcac cggggtagag gaacttctgg atgccctcgg
    18721 agcagaacac cgctccggcg atgaggcgga tcaggagcac cgctggcggc gcgtcgcgca
    18781 ccaccaacgc atgacgcagg gcgttgacga ggccgcgcgc ttcggccatg gctctcccgc
    18841 cattcgtgtc cacgtgacag cagtcggtga cagtcatcgt ggcgcgctct tggcaaccgg
    18901 gccagggacc gcgaccgtat tcgggctcgg tcgccgaccc cgggcgttct cgccgcgcaa
    18961 cctggagacg gggcggatag atggatcagt gggacgcccg acgccccttg gcccacgccc
    19021 aggccccgag tgcggcgact ccccagaaac cgctggccgg catcatggcc gcgcccgttg
    19081 cgcccgtcgc gacgagggcg gccccggcgg tgcgctgggc gcgggtgtcg ccgttctcct
    19141 ccgccgaccg cagcagacga ccggtcgtcc acatcgccgg tgccaaggca agaaaccaga
    19201 aggccgtcgc acggtcgccc cagtcgggga ccgtgctgac caccccgtcg gcggccatgt
    19261 cgccagcggg cttgcggtac aggatgatgc cggtcgcgaa gtgcaggccc gcgagggcct
    19321 ggacccaccg tcccggtgag cgagagatca tggcttgacc ctaagtgcgg cccacccgcc
    19381 atggtgagga gggtcgaggg tgggtcggtc cgctggctag cgctgcgggc ccgcggctga
    19441 agagcccgtt ggggaaattt ttcgctcggt ggtgtcagag tgtcgatccg ggccgaagcc
    19501 gttcgtatag agggtgagaa gccggaacac atccggcggc gataccgagg aggaacggca
    19561 atgcagcact acatgctcac catccaccag ccccagggcg agactccgtc tccagaggtc
    19621 ctggagccga tcatgcggga tctcgaagcc gtcaacgagg agcttagggc ggccggcgcc
    19681 tgggtgttcg ccggaggcat gcaccagccg agcacctaca ccgtgctgcg gcccaaggat
    19741 gacgaagtga tcacgaccga cggcccgtat gccgagggca aggagttcat cggcggcttc
    19801 accgtcatca aggcgcccga tctcgatgcc gccctcgaat ggggacgcaa gttcgcccgc
    19861 gcgatcaccc ttccggtcga agtcaggccc atgcagtacg ggagctgcgg gtgacctccg
    19921 gctcgccgga ggtatcggcc gcggagatcg aacgcgtgtt ccgcgaggag cggggccgcg
    19981 ccgtggctgt cctggtccgc ctcctcggcg acatcgacct cgccgaggag gcggtccagg
    20041 acgccttcgc cgaagcggtc cagcggtggc cgtcggcggg gctgccgccg agtccggccg
    20101 gctggatcat caccaccgcc cgcaaccggt ccatcgaccg actccgacgg gaggcgtccc
    20161 gcaaggaccg ctatgcccag gccgcactcc tgcacgccca tgatgacgcg ccatccgagg
    20221 aggggcctgt gtgcgacgac cggctgcgcc tgatcttcac ctgctgccac cccgcgctcg
    20281 ctccgcactc ccgagtcgcc ttgacgctcc gcctgctggg cgggctcacc acggccgaga
    20341 tcgcccacgc cttcctggtc cccgagagca ccatggccca gcgcctggtc cgggccaagg
    20401 gcaaaatccg cgacgcgcgg attccctacc gggtgccgga cgagtccgac ctccccgacc
    20461 gcctccgggg ggtcttgtcc gtcgtctacc tcatcttcaa cgagggctac gcggcgagtt
    20521 cgggcgaccg gctcgtccga gaggacctct gtgccgaggc catccgcctc ggccgcctcc
    20581 tcgccgagct catgcccgac gaaccggaag tcctgggact gcttgcgctg atgctgctca
    20641 ccgagtcgcg ccgtgccgcc cgcaccacac ccgacggtgc cctcgtgcga ctggccgacc
    20701 aggaccgcga acgctgggat cgcgctctca tcgccgaagg ccaggagatc gtccgcgcct
    20761 gccttcggcg cgatcggccc ggtccctacc agatccaagc ggcgatcaac gccgtccaca
    20821 gcgacgccgc gaccgccgcg gccacggact ggtcgcagat tctgcggctc tacgaccatc
    20881 tctacgcgct cacgccgacc ccgatcgtgg cgctgaaccg agccgtcgcg gtggccgagg
    20941 tcgagggacc cgaggccgcg ctgtcccgcg tcgacgccct cgcctccgac ctcgaccgtc
    21001 accacctgtt ccacgccgtc cgcgccgacc tgctccgtcg cctgggccgg agcgccgagg
    21061 cggtcatggc ctacgaggcg gccctcgacc gcacccagaa cgcggctgag cgcgactttc
    21121 tgcggcgtcg acgcgccgac ctcgattccg cgcgcgagtc cgatcccagg aacggcgacg
    21181 cccgaacgac ctaggcgggg gcgttcggtc cggggccgga cgtcgccgcc ggtgcggccg
    21241 accgggcggg cgggagcggc agtcggccgc tgtcgagggc gtcgatcatg gccatggccc
    21301 cgcctcgggc cgccgcactg aggcccaggg tcgaaggctc cacccggcac ccgcccgcgt
    21361 cgggggcgat ggcgatctcg cggaccgccg cgcggcagtt cgggaggagc cacggggcca
    21421 tcggtacgaa gtaccccccg aggacgaccg ccgccgggtt gacgatgtcg accagtgtgg
    21481 cgatgccgcg gcccagccat gtgcccgccg tgtgcagggt gtccagcgcc gtggcgtcgc
    21541 ccgcctcggc acgctcgacc gcgacgtcga ccaggtgggc gatgccgtcc cccgatagcg
    21601 gcccttccgg cacgcggtcg ggaacggcgg cgcggaggat cggttcgatg cccgcgatcg
    21661 cctccaagca gccgcgccgc ccgcacccgc actccgggcc gtcctccatc agcgggatgt
    21721 ggccgatctc ccccgcgaag ccggtggatc cgcgcagcag gttcccgtcc gtcagcacgc
    21781 ccgccccaat gccgacctct ccggtgatgt agacgaggtc gggtgtgcgg gtgaggtgcc
    21841 cgctgcggaa ttcggcgacc gctccgaggt tggcgtcgtt gtccacgagg atcggcgccg
    21901 tcggcagacg cgcctccgcc atcaggtgcg tcagacgatc gcggagcggg gtgtcgcgcc
    21961 agcccaggtt cggggctcgg gtgacggtgc cggagggcgc gtcgatcagc gcgggcaccg
    22021 cgacactcac cccgatgacg ccgcgcccgg ccagcgcggg atccgccatt gcctccgccg
    22081 tggcccgcgc gatccggtgc gcgcacgcct ccgggccggc cgcccgggcg tcgaaggaga
    22141 tgtgccgggt gaggagttcc tgctcaacga ggtcgaccgc gacgactgac aggtagtcga
    22201 cgttcacctc cagcccgatg gcggcgatcg tgctgtcgtc gagcgcgagc agcacccccg
    22261 ggcgtcccac gcggcgctgg gtggactcgc cggtctcgcg gaccagcccg cgggagatga
    22321 ggtcggcgac caggctggag acggtggttt tgttcagccc tgtggctgcg gcgatggcgg
    22381 cgcgcgagca gggcgcgagg gagcggacag cacgcagcac gacgcccagg ttggcctcgc
    22441 gtaccgcctg gaaaccggtg ggtccggtat tcacgctcga cacgtggtct cgacactccg
    22501 ttcctgtggt cccgcggatg cctggcgcac ggacacctcg ggcgtacccg ctgcgctggg
    22561 gtgccgggcc ggacacggga gtggcgcggg cccaacgggg gtacgcgttc cgtgacttcc
    22621 aacgtacggg gtgtccgtgg aaggctccgg ggcgcccgct ggtcgggcat cttcggtcga
    22681 atgtgggccc cgtctcattg acctccagtt tggttaaggt cagaggctga tgccatgagc
    22741 cgatcggtga cggttccgcg ccgcgcgcga agccagcgga gtccacgacc ccaccaccgt
    22801 gaccgccagc gccgtcaacg acgccgatcg cgacgagggt gtcggctccg tgtcctcgtc
    22861 ctccgccggt cgcgtgtcct gcgtggaccg ctacggagcc ggcgcggaca ttgccacggt
    22921 tcccgggatc gcgtcgaagg cctcttccac cgatgcgatg agcgcggccc gtccgccgcg
    22981 gtcgcggcgt ccggtcccgc gctggtcggc gagccagttc ttggttccgc agcgccaggc
    23041 gctgatggcg aactcgccga ccaggcgcag ccggacatcc tcgtggcggt cgatccccaa
    23101 cttggcctcc agctcctgca ccaggcgccg ctggacgcgc atggattcca cgacggaata
    23161 gtcgatcagg gcgggcgtgt ggtagatgag ccgtcgtgtg cggaggaagc gatcctccca
    23221 gtcgtcgtcc atgcgccgga tcgccagcgt cagcgcgtcc cgcagggcgg ggaagaccgg
    23281 gccgtgcagc tcctcacggg cgacgacgat cacgtaggcg tccaacagtt cgttctgtgc
    23341 cgccagcgcc acctgctcct tggaggcgta gttgcggaag aacgtgcgct tggacacctc
    23401 gaccgcgtcg acgagttcgt cgagtgtgac cgcgtcgaac cccttctcgc tgaacagcgt
    23461 cagcgctgcc tccgccaggg cccgccgcgt gcgcagcttc ttccgctcgc gcagcggcag
    23521 cgtgcggtcc acggaggtcg gccagctcga cggcacggcc cctggtgtgc tcgctgacgt
    23581 ggcggaatgc gctgtcatag ccgatcagcc tagcaagaca cccctcagat gcgaaagcca
    23641 ccaaggggat ttagtcactt gatggcgagt gccactcggt ggcatattgt gtccccgtca
    23701 tcgacccccc acaccccgac cagaaagcct cctccatgac tctgactacc tcggcccgct
    23761 ccgccggccc ggccatagcg ccggagaagg agccgccgga gaaagcagtg ctggagaaat
    23821 gggcgctgac gcgcctcctg cggacgtact tacgcccctc cctcggggct atcggcatcg
    23881 tcatgctgct gcagctcgtc cagaccggcg cgatgctcta cctgccgacg ctgaacgccg
    23941 acatcatcga caacggcgtg gcccggggcg acaccggcta catcgtgggc tccggcacgg
    24001 tcatgctcgc cgtggccctg ctggagctgc tgtgcgcagt cggcgtcgtc tacttcggct
    24061 cgctcgtcgc gatgaccctc ggccgtgacc tgcgcaccgc cttctttcac cgggtccagg
    24121 acctgtcggc gcgcgaggtc ggccacttcg gtgcgccgtc gctcatcacc cgcacgacca
    24181 acgacgtcga gcaggtgcag atgctggcgc tgatgacgct caccatggtg gcgtccgcgc
    24241 ccatcatcgg tgtcggcggc atcgtgatgg ccgtccggca g
//
