LOCUS       NZ_CP022753            24631 bp    DNA     circular CON 23-OCT-2024
DEFINITION  Nocardiopsis gilva YIM 90087 chromosome, complete genome.
ACCESSION   NZ_CP022753
VERSION     NZ_CP022753.1
KEYWORDS    RefSeq.
SOURCE      Nocardiopsis gilva YIM 90087
  ORGANISM  Nocardiopsis gilva YIM 90087
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Nocardiopsidaceae; Nocardiopsis.
REFERENCE   1  (bases 1 to 6142152)
  AUTHORS   Yin,M. and Tang,S.
  TITLE     The complete genome sequence of Nocardiopsis gilva YIM 90087
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6142152)
  AUTHORS   Yin,M. and Tang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-AUG-2017) Yunnan University, School of Medicine, 2
            North Cui Hu Road, Kunming 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 208.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002263495.1-RS_2024_10_22
            Annotation Date                   :: 10/22/2024 21:04:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,549
            CDSs (total)                      :: 5,470
            Genes (coding)                    :: 5,345
            CDSs (with protein)               :: 5,345
            Genes (RNA)                       :: 79
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 61 of 125
            Pseudo Genes (incomplete)         :: 66 of 125
            Pseudo Genes (internal stop)      :: 5 of 125
            Pseudo Genes (multiple problems)  :: 6 of 125
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:05:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 766707
            Orig. end                         :: 791338
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022753.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24631
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="6"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24631
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24631
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14631](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14631)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    71..85
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     misc_feature    116..130
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.88"
                     /tool="antismash"
     gene            991..3078
                     /locus_tag="CDO52_RS03815"
                     /old_locus_tag="CDO52_03805"
     CDS             991..3078
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017580169.1"
                     /locus_tag="CDO52_RS03815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03805"
                     /product="molybdopterin oxidoreductase family protein"
                     /protein_id="WP_026126157.1"
                     /transl_table=11
                     /translation="MPDRQSTATHCPYCALQCGTHLRHSDGVTTVQPSDFPTNQGGLCT
                     KGWTAPSLLDTASRLRSPLVRGPDGELAPSDWDTALDVVSDRIARIRDEHGPDAVGVFG
                     GGGLTNEKAYLLGKFARVALGTSQIDYNGRFCMSSAAVAGTAAFGVDRGLPFPVTDLGQ
                     AETILLAGANPAETMPPLMRHLSRAKLIVIDPRRTRTAESAALHLQPVPGTDLALALGL
                     LHLTVTEGLLDKDYLAERTTGFEDAWERALSWWPERVERVTGVPVAEQREAVHMLGAAE
                     RAYVLTGRGAEQHSKGTDTVAAFIDLALALGLPGREGSGYGCLTGQSNGQGGRELGQKA
                     DQLPGYRSITDPEARARIAEVWGVAPEALPGPGRSAYELFDALGTAGGPRALLVFDSNP
                     AVSAPRSDRVTERLASLDLLVVADFVPSETAQLADVVLPVTQWAEEEGTMTNLEGRVLR
                     RRRLLSPPPEVRSDLDILHGLAVRLGEPGHRFPTEPREVFAELRRATMGGKADYSGITY
                     DRLDAGEALHWPCPLLPESRAPHPGTPRLFLDRFAHPDGRARFAAVDHRAPAETTDDAY
                     PLYATTGRVLAQYQTGAQTRRVPELNEAVPEPFVEIHPDTAERAGLRHDDRAAVISARG
                     RTVARVRLDGSLRTDTVFLPFHFPGDGRANLITNTVLDPQSKMPEFKVCAVRIEPISEP
                     A"
     gene            3075..4463
                     /locus_tag="CDO52_RS03820"
                     /old_locus_tag="CDO52_03810"
     CDS             3075..4463
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019604.5"
                     /locus_tag="CDO52_RS03820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03810"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_094932206.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.9e-39, bitscore:
                     133.4, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 2.1e-10, bitscore:
                     39.2, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDILIIGDGPAAHRLVERLRHHGHQDAVTVLGREPGPTHSGAPP
                     LPFSGHSSPYQHGFPEGTRVRRGVTATRIDRARRLVHTDDGTAHGYDTLVLATGARPRV
                     PDIPGVLTAEGRLHASVFTPRSLAARECRPAGSVAVLGAGAGGVEAALALRRAGREVAL
                     VDAASHPMKDRLDDAAGRLLAGILHDEGVETHLGHVAVAFEPGKLVLDGGRVLAADVLL
                     LCTDAAPETGLAHGAGLSVDCGVLIDDEMRTDDPRIRAIGGCARHQEGGGETAYSLPQA
                     WDQADTLALLLTGGRPHYRVAAPITRSRTPGVDVLSLGPPSALDHAAELVTLSDPSRRR
                     YAKLALHDHKLTAAMVIGLPKAIASLVQLYDRGVSVPSDRLALLLGTSSVGSGTVELPD
                     DAVVCNCNNVTKRSLAQAWHQGAREVAELAEATRATTGCGTCADAVRRICGVLEKASGE
                     GDAS"
     misc_feature    3210..3212
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    3618..3620
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4460..5680
                     /locus_tag="CDO52_RS03825"
                     /old_locus_tag="CDO52_03815"
     CDS             4460..5680
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620642.1"
                     /locus_tag="CDO52_RS03825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03815"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_017620642.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5.8e-52, bitscore:
                     175.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTLVVVGHGMIGHHLVEMLRAHDRANTWRVIVLGEEPRPAYDR
                     VALSSYLEGKSFDDLGLVSHECLGDPWVELRTGVTVTGIDRQEQKVTCADGTEVSYDAL
                     VLATGARPFVPPVPGHDLPGCFVYRTLDDVDAIRAAAVPGRPGVVIGGGLLGLEAANAL
                     RLLGMRPYVVEMAPRLMPMQVDEGGGQILTRLIGDLGVTVCCGVSTASIDAGPDGRVRG
                     MTLADGTTLETDLVVFSAGVRPRDDLAGLMGLDTGDRGGFLVDDDCRTADPRIWAIGDC
                     AAVRGRCYGLVGPGYRMAEVVAEQLLQADDGRGGRTRFTSPDTSTKLKLFGVEVASFGD
                     AHARTDDAVEFIREDTMAGTYAKLVIDSSATTLLGGVLVGDARALPVLRSLVGHELTAS
                     PDQLLAS"
     gene            complement(6162..10001)
                     /locus_tag="CDO52_RS03830"
                     /old_locus_tag="CDO52_03820"
     CDS             complement(6162..10001)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009082897.1"
                     /locus_tag="CDO52_RS03830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03820"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_232524373.1"
                     /transl_table=11
                     /translation="MAARKASMTSAASTTGPSAERSATPGGPARPTPFRARWTTRLLRS
                     CLRHRALTGAVVLAAVLGTGLGAIGPLVTQVAIDGAVAGRVDHIGALIALLLAAAVLQF
                     AGSFARQFLAGKLALSVQHDLRTAAFASVQRLDGGKQDALRTGQVMSRANIDLQLVQGL
                     LSMAPQALGGGVLIVASLAAMLWLSPPLTVIALVVLALFVVVTVRASGRMFPATWAVQQ
                     RTAEIAQHIEETVTGVRVVKGFGQERRETDRLTEQARLLFGERMRVARMQATPSATLGV
                     LPYVGQIAVLLLGGWLALRGDVTIGTLVAFAGYMVTLTAPSGVLSNLVITAQLVRPAAE
                     RVYDLTDVRSDIGDAPDAVDVPDDGPIGVELDGVRFGYTRDEPVLEGMSLRVEPGETVA
                     VIGPSGSGKSTVSLLIPRFYDVDDGAIRIGPPGAEVDIRRTRLRSLRQSVGVVFEEPFL
                     FSCSIADNIAYGHPDATREEIRAAARAAGADGFISALPDGYDTRVGERGLTLSGGQRQR
                     VALARTLLSDPRVLLLDDATSAVDTATEAAITATLREVTADRTTVLIAHRRSTLGLADR
                     IAVLDGGRVVDVGTEEELLTRCPLFAELLAGPDQSIDERTPVTGATEQAPGAALLWPDT
                     GAAEGADLDHAGGLPGNVDLPELRERIRRLPAATDRPDPRLAEKRSEPEPRADATANGT
                     GAASGGGDRSAGVWWVLRPVRRLLAVAIALVAADALAVTVLPAMIRSGMDRGVVNGDMT
                     DIAAVSGLALLIVAANWFVLRAQPRVTTRTGESALFALRLRSYRHLQRLGLDYYEREPG
                     GRIMTRMTTDVTALSTFVESGLTIAVVNFATVLGMAVAMLVIDAKLAVAGLAVLPVLLV
                     ATLVFRHYSSLAYDRSREEIGDVNADLQENIAGARTSQAHGREESAEKRFSDLSDRYRR
                     TRLRAQRYIALYFPFVTFLGDIATAVVLGVGAYRVASGTLTVGVMVAFLLYLGLFFAPF
                     QQLSVVFDSYQQARVGVRRIGELLRTPVSVPEAATPVPVPPRLRGEVELAVVGFGYPGS
                     EEPALSDVTLHVRPGETIALVGATGAGKSTVVKLIARLYDVTAGRVLVDGVDVRDYAPE
                     AFRRRLGIVPQEPHLFTGDIADNIRYGRPDADDAEVEEAVRAIGALDAIAALPGGFRHR
                     VGERGQGLSTGQRQLIALARVELADPDLLLLDEPTAALDPATEAAVLTAGDRLARSRTT
                     FVVAHRLASAARANRVVVLDQGRVVEVGPHDELCAQEGHYARLWRYGTDPAAIG"
     gene            complement(10001..11182)
                     /locus_tag="CDO52_RS03835"
                     /old_locus_tag="CDO52_03825"
     CDS             complement(10001..11182)
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620643.1"
                     /locus_tag="CDO52_RS03835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03825"
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_232524374.1"
                     /sec_met_domain="LANC_like (E-value: 4.3e-23, bitscore:
                     80.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMTAAEDQVGLARTLYADATESITRDPDFTLLLDHALTAMEFRRA
                     LGDDGAPSTAARDSFREAMGLLRSASNVGPWLYRGAAQAGWVAIQLARQHGTEASGLAP
                     IDDIVLQWATAFPDDLDIDLPMGLLGLGVYGLAHPEASFREKLTSGILDVIENRTERDE
                     NGLFFRLADSEARRADQSAGCRIIGVAHGAAGLVSYLASVSRSDTSVRPRARALLDDAL
                     RWLLSQGSDVNGSVFPHRVEMRYAPSRATWCSGDPGVALALSVAAQATGSPGAASAARR
                     TAEAVIARPDGDCGVMDGCVCHGAAGLCWFGRHMSDRFGIAGAGQFADRWVRYLADQRA
                     AGHLTYFGPEGMVRDASFLEGDAGVALALLYTATGVTPVWEQLVLATPITAGA"
     gene            complement(11179..14631)
                     /locus_tag="CDO52_RS03840"
                     /old_locus_tag="CDO52_03830"
     CDS             complement(11179..14631)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013155687.1"
                     /locus_tag="CDO52_RS03840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03830"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_094932208.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 5.1e-39, bitscore:
                     132.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 6e-27, bitscore:
                     93.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRVPLFSVDEAARMVADEDVADPIATMAVSLAAGPYVRDAAVSG
                     DQRARDTLARYLARMGGRATPYGLFAGTAPVSVGEERDLALGPRDRHRVRVRVDVQALE
                     EAVRAAADAVGPLQWPLRTNPIARADGDVLRFAKSGDASADVVSMRLTPAIAAVLRVLG
                     DGEVIGADIVAALRADNPGFSEDQMAGFLTRLVDGGLIERSLGLIEPGVEPAERAVDLL
                     EAMGATEQADALRTLLADATGVRPLDPALTGTLDAGWRAAASHIPSFAEVKQAQRFDVH
                     PEMDMSAATLDRRSSDDLQRAILRVAALQNGGGAAGGSAFSIDEFRDAFRARYEDAEVP
                     LLSALDLESGVLRSWHRSVSELAVNAGVRAPEESSLPRVNPELLKLYDRWTRDGTPVDI
                     PTDANANERAKASTPNGRRPESVGGTASKERERAENTDANANERAKASTPNGRRPEGVG
                     GTASEERERAENTDANANERAKASTPNGRRPHSVGGTASKEHERAENTDANANERAKAS
                     TPNGRRPHSVGGTASEEHERANDTPAASTTGARAALAVLLGDHPEGLHSMLVGGVGRAP
                     HALLARFSLNRDGMRQRLSDAVHGAEEMVGDAVAAGAPSDAPGVFGPGVPTGPNATADA
                     DTAGAPDTAPIHAELVYHPGGRIGNVLIRPRLLDDTIALTGASGGTLALDRLLIQLRGD
                     EFRLRDSLTGRPVLVELNTAHNVDFHGLDPVYAVLGHLASSGGVGWSWGALAHLSHLPR
                     VTCGPVVVAPEQWRLARADIRDVLHDPDPAGHLRRLLPGLGDRRWVGVGDYDHVLPIDL
                     RSARSVGAALAKEAKGPDTASVKIIEMPQLEAPAVRGPSGGHVAEAVIPFSPVHRTPPR
                     PGTGADAFDADRGRAWVYFSYFCGQASADAVVTRAKQLADELHRSGAVTDWFFLRYTDG
                     GYHVRVRMRPIDGAARAHVVAAMDALGGALRAEGLIGRSVMDDYIPEVSRYGGADNLAA
                     AERLFTASSDQVAAFLAARPTEELRLYQAVADAVGWCSALFDSTDEQRAFLRLCQSGTS
                     LSFTKKGNPLGKFHRAHDRALRDHLADAQGDEQVAKALAALSSSVRQTLTGRRGWSVFG
                     SALHLHCNRLFAFDAVRLEYLAYELAERRIHQLQALDGVGGKA"
     gene            complement(14649..15644)
                     /locus_tag="CDO52_RS03845"
                     /old_locus_tag="CDO52_03835"
     CDS             complement(14649..15644)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620644.1"
                     /locus_tag="CDO52_RS03845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03835"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_232524375.1"
                     /transl_table=11
                     /translation="MDRTTATTPTAASATATATPARTPANADPPPPLGLLEYLDLGDHR
                     SVRAKRETAFEAALLAEQVGYQRLWLPEHHSTGVPSPNPLLLAGVLGSHTTRIRIGTAV
                     TLIRVRDPHLTAEDVASAAFFCGDRLDVGFGRGDVAGSAADALAYLRKGGDATDEAIRT
                     VVSVLDDGRDWIDPLDTPYERWLHGAGTRSAELAGEMGFNYCHALFFNVDVDACTRTLN
                     SYRAAFPNGRTAVAAALVANDDPVIARTDSIRAGIKVNCAGTAEQCAAAVCKLLELTGA
                     DEVVITEMSRSADDHLRALKEIFGLVAERLGGRPRSAGPADRAATGGEER"
     gene            complement(15851..16030)
                     /locus_tag="CDO52_RS03850"
                     /old_locus_tag="CDO52_03840"
     CDS             complement(15851..16030)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620645.1"
                     /locus_tag="CDO52_RS03850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03840"
                     /product="hypothetical protein"
                     /protein_id="WP_017620645.1"
                     /transl_table=11
                     /translation="MTAPNAKANVEFDLDIDMETFSTPGGGQLSANNIDARGPITLGTT
                     CWGTTCPSANTVSC"
     CDS_motif       complement(15950..16030)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTAPNAKANVEFDLDIDMETFSTPGGG"
                     /locus_tag="CDO52_RS03850_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15851..15949)
                     /prepeptide="core"
                     /locus_tag="CDO52_RS03850_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-3.40"
                     /molecular_weight="3091.4"
                     /monoisotopic_mass="3089.5"
                     /core_sequence="QLSANNIDARGPITLGTTCWGTTCPSANTVSC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTAPNAKANVEFDLDIDMETFSTPGGG"
                     /leader_location="[15949:16030](-)"
                     /alternative_weights="3109.4"
                     /alternative_weights="3127.5"
                     /alternative_weights="3145.5"
                     /alternative_weights="3163.5"
                     /alternative_weights="3181.5"
                     /alternative_weights="3199.5"
     gene            16394..17215
                     /locus_tag="CDO52_RS03855"
                     /old_locus_tag="CDO52_03845"
     CDS             16394..17215
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620646.1"
                     /locus_tag="CDO52_RS03855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03845"
                     /product="Mbeg1-like protein"
                     /protein_id="WP_017620646.1"
                     /transl_table=11
                     /translation="MTTPVFEQTITGYSLRSAHGLAQASQLAYQDEDQIKTTTAVWGMP
                     ECRFFQVEFEQPFPIDDTQAYVAANDKVVVVAFRGTELAQLRDWLSDANGLLAPDPNGQ
                     GMVHMGFNQALDAVYPQVLNAVSEMRGNGQSICITGHSLGGALAMLAAARMRFGDSRLL
                     ADGVYTFGQPRTCDPLMARTFDREFKGRMFRFVNNSDIVPQLPPEPLYHHVDEEKYFDA
                     DGRLREKKMSLLGGLTDKVKGQTADPMALGTDQIRDHGIARYIANLEKAMG"
     misc_feature    16404..16424
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.34"
                     /tool="antismash"
     gene            complement(17353..18204)
                     /locus_tag="CDO52_RS03860"
                     /old_locus_tag="CDO52_03850"
     CDS             complement(17353..18204)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017623879.1"
                     /locus_tag="CDO52_RS03860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03850"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_026126159.1"
                     /transl_table=11
                     /translation="MGGDSQAATGLTRRRRRLSDQETERRMLQAAMDQVNRAGLTVSLE
                     HISFEDVIRDAGVSRSAVYRRWPYKDLFFSDLLKELARGTSPAIVEENPEARRAVDQTI
                     LDRLDWLKTPSLRIALATEILRQGAPAELQTFLRSPEWRTYVALHATFLSLPDGDLRTE
                     VQAALTESERNVTAGLAAAYERVASLLGLRLRPALSTGFETLATLANAMVRGLVVMAPT
                     TPALSEETVRADLFGAPDPADWTLPGLALGALAAAFLEADPDAEFDDDRIAEIRRALAS
                     EG"
     misc_feature    complement(18233..18247)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.07"
                     /tool="antismash"
     misc_feature    18239..18252
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.4"
                     /tool="antismash"
     misc_feature    18381..18396
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 23.65"
                     /tool="antismash"
     misc_feature    complement(18381..18397)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.72"
                     /tool="antismash"
     gene            18398..19078
                     /locus_tag="CDO52_RS03865"
                     /old_locus_tag="CDO52_03855"
     CDS             18398..19078
                     /EC_number="3.5.4.25"
                     /GO_function="GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0009231 - riboflavin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620648.1"
                     /locus_tag="CDO52_RS03865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03855"
                     /product="GTP cyclohydrolase II"
                     /protein_id="WP_017620648.1"
                     /transl_table=11
                     /translation="MRDQDTDLTDVAESDLTTRRGTFRAVAFRDPLDGHEHMALVLGEV
                     VDREDVLVRVHSECMTGDIFGATRCECGEQLTSALDAIVREGSGVLVYLRGHEGRGIGL
                     VAKVRTHILQDEQGLDTIDSATSLGLPVDVRDYGPAARVLHYLGAASVRLLSNNPDKIG
                     ALEAYGIRVSEQVPLLAPAHNGNIAYLTAKRDRLGHDLPQVEEVSSASLCDSGARGQED
                     GGRG"
     gene            19071..19886
                     /locus_tag="CDO52_RS03870"
                     /old_locus_tag="CDO52_03860"
     CDS             19071..19886
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1207: inositol monophosphatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620649.1"
                     /locus_tag="CDO52_RS03870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03860"
                     /product="inositol monophosphatase family protein"
                     /protein_id="WP_017620649.1"
                     /transl_table=11
                     /translation="MADVAGAAFAALLPVAQEATAIARRIVREHAPRAVTEKGERDIVT
                     DVDLAVEDAVRTFLARETPNIGLLGEEHGRTGGADGEPWWVLDPVDGTANLACGIPLCA
                     VSLGLVWEGRAVVAVIDLPFLDTGYTATEGAGAFCDGERIRASGHSAPADAVVSIGDFA
                     VGEGADAKNRVRLDLLGRLGARVRRIRMLGTAAIDLAWTAHGKLDAAVILANRPWDTAA
                     GVLLVREAGGVVLDRDGSPHSVDSSATIAVAPGLREHIMLEVAHAYGIE"
     gene            19873..20667
                     /locus_tag="CDO52_RS03875"
                     /old_locus_tag="CDO52_03865"
     CDS             19873..20667
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017568740.1"
                     /locus_tag="CDO52_RS03875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03865"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_198345825.1"
                     /transl_table=11
                     /translation="MGSSDAHAAPLSAGVRFRVTSASAGPAVGAAAQAALLAVLAAAAG
                     LGAAGWIAGSAYAVALGGLLTRALYRDGHPGMRPADRVTLARAVLVGGVMALVADEVAG
                     RPLDGGALGTLVLLAAVALALDGVDGLVARRTNTTSRLGARFDMEVDAFLILVLSVHVS
                     LHLGAWVVAIGAMRYAFAAAATVAPWLHGDLPLSTARKAVAVVQAAALIAASASVLPHS
                     AATAVVAAALALLAWSFGRDVWWLWRTRSARLRTGPDTDREG"
     gene            20667..21641
                     /locus_tag="CDO52_RS03880"
                     /old_locus_tag="CDO52_03870"
     CDS             20667..21641
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017607830.1"
                     /locus_tag="CDO52_RS03880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03870"
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="WP_094932210.1"
                     /transl_table=11
                     /translation="MEHTARAFWLRSPGVGEIRSVPVPEPAPGDVVVRTRYTGVSRGTE
                     SLVFRGGVPESQREAMRAPFQEGGLPGPVKYGYLNVGTVEQGPSELVGRDVFSLYPHQT
                     RFVVPAGAVVPLPEGVPAERAVLAGTVETAVNAIWDAGPLIGDRVAVVGAGMVGCCVAR
                     LLADIPGARVQLVDTEPERADVAECLGVAFAHPAEAAGQCDLVFHASATEAGLATSLDL
                     LGDEGQVIELSWYGDREVRIPLGESFHSRRLAIRASQVGVVSPARSRRRSLADRLSLSL
                     RLLTDPAFDTLITGESPFERLPDLMPLLADGRIPALCHRIAYG"
     gene            21714..22112
                     /locus_tag="CDO52_RS03885"
                     /old_locus_tag="CDO52_03875"
     CDS             21714..22112
                     /EC_number="4.1.2.50"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTPS"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017602952.1"
                     /locus_tag="CDO52_RS03885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03875"
                     /product="6-carboxytetrahydropterin synthase"
                     /protein_id="WP_017620652.1"
                     /sec_met_domain="PTPS (E-value: 6.4e-25, bitscore: 85.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFSVTVRDHLMVAHSFRGEVFGPAQSLHGATFIVDASFRRPELDD
                     DGIVVDIGRATQELNSVLADLNYRNLDEVPEFAGVNTSTEFLAKVIADRIADRVAQGAL
                     GEQARGVTELKVTLHESHIAWASYERAL"
     gene            22109..23218
                     /locus_tag="CDO52_RS03890"
                     /old_locus_tag="CDO52_03880"
     CDS             22109..23218
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620653.1"
                     /locus_tag="CDO52_RS03890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03880"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_017620653.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 7.1e-29,
                     bitscore: 99.0, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPTFVLPGGVDDPTTPSGGNVFDRRLCRELARMGRPVREVAIP
                     GTWPEPDASGRDRLARALDALPDGAAVVVDGLVACGVPEIVVPSARRLRLGVLVHLPLA
                     DETGLSTDHAAELDAAERDTLRAARAVIATSRWAARNIKDRHSLDHRRVWTVEPGTDAA
                     PLVSGTDHGVRFLSVASVTPRKGHDLLVRALAGITDLRWGCVCVGPAPPESAFASEVRR
                     LVGQLGLGGRIDFSGPLSGDALAHAYAEADLLLLPSRAETFGMAAAEALARGIPVLATT
                     AGALPDTLGQARGGTVPGLLVPPNDVQALAGSLRSWLMDGALRDRLRAAARLRRAELRP
                     WEAAARDMTVILDRMHEPRHPRPQRENAW"
     gene            23215..24096
                     /locus_tag="CDO52_RS03895"
                     /old_locus_tag="CDO52_03885"
     CDS             23215..24096
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017620654.1"
                     /locus_tag="CDO52_RS03895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CDO52_03885"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_017620654.1"
                     /transl_table=11
                     /translation="MSAPGSPRFEADWLALREGADADARDAGLLVPLRAHLAAEHGRRR
                     GGSLNIHDLGSGTGSMARWLAPLLDGPQHWVLHDRDPELLERAAGFPPEPAADGAPVTV
                     RTRLADLTELDAVDLKGADLVTASALLDLLTADELNGLAEACTGVGCPVLLTLSVAGHV
                     VLTPDHPLDADIAAAFNAHQRREVQGRRLLGPDAPDAAARAFRRRGAPVYRRSSPWRLG
                     PEQRRLMRQWLEGWVAAAVEQRTELSTEARTYVEWRLGECASGRLRAEVHHVDLLVLPD
                     GPAAEGRHEERS"
ORIGIN
        1 cctggcggag cagggagccc gcgcacggat ccccgtcctg cgcccgaaga acgtcaacga
       61 cccggaagcg atcacggctc tcaatgccct agaaccggac tacctgctga tcgctaattt
      121 ccagcagatc ctccgggaac ccgtactcgc cctaccccgc cgggcggtca tcaacttcca
      181 ccccagcccc cttccgcgct atgcgggtct cgcgccgttc ttctggatgg cgctgaacga
      241 agagaaggat gccggcgtca ccgcgttgat caccacgccg ggggtagatg agggacctgt
      301 actcgcccag cgtcccgttc ggctcaacgg cacggaaacc tcgggggaga tccgcgaccg
      361 gcttttcacg gaatcccgca gcctgctcca tgatgtggtc ccccggctgg caacgggaga
      421 actcacggcg gttccccagg acacgcgaca gagaagctac ttctccaatc cgaggcctga
      481 agacaccgtc atcgactggt cctggacggc ggaccgcgtg atgcgcgtgg tgcgggcatg
      541 tgctccccag cccggtgccc tgatcgccat gaacggtggc gagatccgta tccacgacgc
      601 gcgcatactc tccgaagcga gggctccggc gccggtggcc gctccgggca ccgtcgggtc
      661 cgacgctcgg catgggttgg ccatctcctg cgcggacgcg tggatcgaag tggtttcgct
      721 gagttggcac cccgaaacgg tgctgaccgg ccatcaccaa gggctgcgcg tcgaccacca
      781 tctctcccca gacctggcgg gactcctcgc gtctcgcggc gaatagccct cgaaaaggtc
      841 ggccgtgact gattcccgga gccggaagaa tttgtgaatc gccacggtcg ggggcatccg
      901 ggaatgctgc ggctggaatt tccgccctat attcatcccc cttctgttcc tcattcgcgt
      961 aagacgcctt tgtgcttagg gagaattccc gtgcctgacc gacagtcgac cgctacgcac
     1021 tgtccttact gcgcactgca gtgcggaacc cacctgcgtc actcggacgg cgtgacgaca
     1081 gtgcagccat ccgacttccc gaccaaccag ggcgggttgt gcacgaaggg atggaccgca
     1141 ccgagtctcc tggacaccgc gtcccgcctg cgctctcccc tggtgcgcgg tccggacggg
     1201 gagctggcgc cgtccgactg ggacaccgca ctggatgtcg tctccgaccg catcgcccgg
     1261 atcagggacg agcacggccc ggacgcggtt ggcgtgttcg gcggaggcgg cctgaccaac
     1321 gagaaggcgt acctcctggg aaagttcgcc cgggtcgcac tgggaacaag ccagatcgac
     1381 tacaacgggc gcttctgcat gtcctcggcc gccgttgccg gcaccgccgc gttcggcgtc
     1441 gaccgcgggc ttccgttccc ggtcaccgac ctcggacagg cggagacgat ccttctcgcg
     1501 ggcgcgaatc cggccgaaac gatgccacct ctgatgcggc acctgtcgcg ggcgaagctg
     1561 atcgtgatcg accctcgccg tacccgtacg gccgagagcg ccgcgctcca cctgcagccc
     1621 gtgcccggga ccgatctcgc cctggcgctg gggctgctgc acctgacggt caccgaaggc
     1681 ctgctcgaca aggactacct ggccgagcgc accaccggct tcgaggacgc ctgggagcgg
     1741 gcgctgtcct ggtggccgga gcgggtcgag cgggtcacgg gtgtgccggt cgccgagcaa
     1801 cgcgaagcgg tacacatgct cggcgcggct gagcgggcct atgttctgac cggtcgcggc
     1861 gccgagcagc acagcaaggg caccgacacg gtcgccgcgt tcatcgatct cgcgctcgcc
     1921 ttgggcctac caggccgcga gggcagcggc tatggctgcc tcaccggcca gagcaacggt
     1981 cagggcgggc gcgagctggg ccagaaggcc gaccagctcc ccggctaccg gtcgatcacc
     2041 gaccccgagg cacgagcccg gatcgccgag gtgtggggcg tagcccccga ggccctcccc
     2101 ggtccgggcc gcagcgccta cgagctcttc gacgcactgg gtacagcagg cgggccgcgt
     2161 gcgctgctgg tcttcgactc gaacccggcc gtctcggccc cgcgctccga ccgtgtcacc
     2221 gaacggctcg cctccctgga cctgctcgtg gtggccgatt tcgtgccgtc ggagaccgcg
     2281 caactggccg atgtggtcct tccggtgacc cagtgggcag aggaagaggg caccatgacc
     2341 aacctggagg gccgggtgct gcggcggcgc cgactgctgt ccccgccccc cgaggtccgc
     2401 agcgacctgg acatcctgca cggcctcgcg gtgcgcctcg gcgagcccgg acaccgcttc
     2461 cccaccgaac cgcgcgaagt attcgccgaa ttgcgccgcg ccaccatggg cggcaaggcc
     2521 gactactccg gcatcaccta tgaccggctc gacgccggtg aggccctgca ctggccatgc
     2581 ccgctgctcc cggagagccg cgcgccgcac cccggcacac cgcgcctgtt cctggaccgc
     2641 ttcgcgcacc cggacgggcg cgcccggttc gccgcggtgg accaccgagc ccccgctgag
     2701 acgaccgacg acgcctaccc cttgtacgcc accaccgggc gagtcctggc ccagtaccag
     2761 acgggcgcgc agacccgcag ggttcccgag ctcaacgagg ccgtgcccga gccgttcgtc
     2821 gagatccacc ccgacaccgc cgaacgagcc gggctgcgcc acgacgatcg ggccgcggtc
     2881 atctcggcac ggggccgcac ggtggctcgc gtccggctgg acggcagtct tcgtacggac
     2941 actgtctttc tgccgttcca cttcccgggc gacggccggg ccaacctgat caccaatacc
     3001 gtcctggacc cgcagagcaa gatgcccgag ttcaaggtct gcgcggtccg tatcgaaccg
     3061 atttcggagc cggcatgagc gacatcctga tcatcggcga cggtcccgcc gcccaccgtc
     3121 tcgtggagcg actgcgccac cacggccacc aggacgcggt caccgtcctt ggccgggaac
     3181 ccgggccgac gcacagcggc gcgccgccgt taccgttctc cggccactcc tcgccgtacc
     3241 agcacggctt tccggagggc acgcgagtac ggcgcggtgt caccgccacc cgtatcgacc
     3301 gcgcccgtcg tctggtgcac accgacgatg gcacggcgca cgggtacgac accctcgtac
     3361 tggccactgg cgcgcgtccc cgcgtcccgg atatccccgg tgtgctgacg gccgaaggtc
     3421 ggctccacgc ctcagtgttc acgccgcgtt cgctcgccgc gcgcgagtgc cgtcccgcgg
     3481 gcagcgtggc cgtgctcggt gccggggccg ggggtgtcga ggcggccctc gcactgcgcc
     3541 gggcgggccg cgaggtcgcc ctggtcgacg ccgcctccca ccccatgaag gaccggctgg
     3601 acgacgccgc gggacgatta ctcgccggga ttctgcacga cgagggtgtg gagacgcact
     3661 tgggccacgt ggcggtggcg ttcgagccgg gcaagctggt cctggacggc ggacgagtcc
     3721 tggccgccga cgtcctgctg ctgtgcaccg atgccgcgcc cgagaccggc cttgcccacg
     3781 gcgccgggtt gtccgtggac tgcggggtgc tcatcgacga cgagatgcgt accgacgacc
     3841 cccgtatccg cgcgatcgga ggctgcgcgc ggcaccagga gggcgggggt gagaccgcgt
     3901 actcccttcc gcaggcctgg gaccaggccg acactctggc cctgctgctg accggcggcc
     3961 gtccgcacta ccgcgtcgcg gcgccgatca ctcgctcccg gacccccggc gtcgacgtcc
     4021 tctccctcgg cccgccgagc gcgctggacc acgcggccga gctggtgacg ctctccgatc
     4081 cgagccgccg ccgctacgcg aagcttgcgc tgcacgacca caagctcacc gccgcgatgg
     4141 tgatcggcct gcccaaggcc atcgcgagcc tcgtccagct ctacgaccgc ggcgtatccg
     4201 tgccgtccga ccggctcgct ctcctcctcg gcacatccag tgtcggttcc ggcaccgtcg
     4261 agctgcccga cgacgcggtg gtctgcaact gcaacaacgt caccaaacgg tccttggcac
     4321 aggcgtggca tcaaggtgcc cgcgaggtcg cggaactcgc cgaagcgacg cgtgcgacca
     4381 ccggctgcgg cacctgcgcg gacgccgtgc gccgcatctg cggtgtgctc gaaaaagcct
     4441 ctggagaggg tgatgcctca tgacgcgcac gctcgtggtc gtcggccacg gcatgatcgg
     4501 ccaccacctc gtcgagatgc tgcgcgccca cgaccgggcc aacacctggc gggtcatcgt
     4561 cctgggcgag gaaccgcgcc ccgcctacga ccgggtcgcg ctctcctcgt acctggaagg
     4621 caagagcttc gacgacctcg gtctggtcag ccacgagtgc ctcggcgacc cgtgggtgga
     4681 gctcagaacc ggcgtcacgg tgaccgggat cgaccggcag gaacagaagg tgacctgcgc
     4741 cgacggcacg gaggtcagct acgacgcgct cgtgctggcc actggcgcgc gcccgttcgt
     4801 gcctcctgtc cccggacacg acctccccgg ctgcttcgtc taccgcaccc tggacgacgt
     4861 cgacgccatc cgcgcggccg ccgtcccggg gcgcccgggc gtggtgatcg gcggcggtct
     4921 gctcggcctg gaagcggcga acgctctgcg cttgctgggg atgcgcccgt acgtcgtcga
     4981 gatggcgccg cgcctgatgc cgatgcaggt cgacgagggc ggcggtcaga tcctgacccg
     5041 gctcatcggc gacctcgggg tgaccgtgtg ctgcggagtg agtaccgcct ccatcgacgc
     5101 gggcccggac ggccgggtgc gcggcatgac cctggccgac ggcaccaccc tggagaccga
     5161 cctcgtggtg ttctccgccg gagtccgccc gcgcgacgac ctggccggcc tcatgggtct
     5221 ggacacaggc gaccgcggcg gcttcctcgt cgacgacgac tgccgcacgg ctgacccccg
     5281 catctgggcc atcggcgact gcgcggcagt gcggggccgc tgctacgggc tggtcggccc
     5341 cggctaccga atggccgaag tcgtcgccga gcaactcctc caagccgatg acggccgtgg
     5401 cggccggacg cgtttcacca gtcccgacac ctccaccaag ctcaagctgt tcggtgtcga
     5461 agtcgcgagc ttcggcgacg cccacgcccg gaccgatgac gcggtggagt tcatccgcga
     5521 ggacaccatg gcaggcacct acgccaagct cgtcatcgat tccagcgcga cgaccctgct
     5581 gggaggtgtc ctcgtcggtg atgcgcgcgc cttgcccgta ctgcgttccc tcgtgggcca
     5641 tgagctcacc gcgtcacctg atcagctgct cgcgtcctga cacgggatcg cgtcgtcgcg
     5701 cacgaggctg ggctcggaca cataacgctt tcgaacccca tgagtggagc gcacggagct
     5761 ccaccaccga aggggacgcc acagtcgtag catcgcttcg ggcctcttcc gcacgtcgca
     5821 gtaggtcggc gtgaccctcg gcggctcggc ggacgacgcc ggcctccatc tcctgggcgc
     5881 cgctttcacg gcactcagcc tcgggatggt ggcgttggcc gccgtgtacg cgctacgggg
     5941 ccgcgcagcc cgcgtccgcg cggccgccct ggcggtcccg gccgctgggg cggtgctgtg
     6001 cctggcgacc gacaaccacg gggccgccct cgtggcgggc gctgcggtgg ggggtgctgc
     6061 tcttggtggt gcccgggcag gtgcgagcag gcgcttgggc gtcgacgagg gtccgcgtgt
     6121 agcccctggc ggcggctccc gcggggcgct cgggccactc ctcagccgat ggcggcgggg
     6181 tcggtgccgt agcgccacag gcgggcgtag tgaccctctt gggcgcacag ttcgtcgtgc
     6241 gggcccacct ccaccacgcg gccttggtcg agcacgacga cgcggttggc gcgtgccgcc
     6301 gacgccaggc ggtgggcgac cacgaacgtg gtccgcgacc gggccagccg gtccccggcg
     6361 gtcaggacgg cggcctcggt ggccgggtcg agggcggcgg tgggttcgtc gaggagcagg
     6421 aggtccggat cggccagctc cacgcgggcg agcgcgatca gctgccgctg ccctgtggac
     6481 agcccctgcc cgcgctctcc gacccggtgc cggaacccgc cgggcagtgc ggcgatggcg
     6541 tcgagcgcac cgatcgcccg taccgcctcc tccacctcgg cgtcgtcggc gtccgggcgc
     6601 ccgtagcgga tgttgtcggc gatgtccccg gtgaacaggt gcggctcctg cggcacaatg
     6661 cccaggcgtc gccgaaaggc ctcgggtgcg tagtcgcgga cgtcgacgcc gtccaccagc
     6721 acgcgccccg cggtcacgtc gtagaggcgg gcgatcagct tcaccacggt cgacttcccc
     6781 gcgcctgtgg caccgacgag cgcgatcgtc tcgccgggcc gtacgtgcag cgtcacgtcc
     6841 gacaacgcgg gctcctcgct tccggggtag ccgaacccca ccaccgcgag ttccacctcg
     6901 ccgcgcagcc ggggcgggac cggtacgggg gtggcggcct ccggtaccga caccggcgtg
     6961 cgcagcagct cgccgatcct gcgcacgccg acccgcgcct gctggtagct gtcgaagacg
     7021 accgagagct gctggaacgg cgcgaagaac aggccgaggt agaggaggaa ggcgaccatg
     7081 acgcccaccg tcagggtgcc cgacgccacc cggtaggcgc ccacacccag gaccacggcg
     7141 gtcgcgatgt cgccgaggaa ggtgacgaac gggaagtaga gggcgatgta gcgctgggcg
     7201 cgcagccgcg tgcgccggta gcggtcggac aggtcgctga accgcttctc ggcgctctcc
     7261 tcccggccgt gggcctgcga ggtgcgcgcc ccggcgatgt tctcctgcag gtcggcgttg
     7321 acgtcgccga tctcctcgcg cgaccggtcg taggcgagcg acgagtagtg gcggaagacc
     7381 agcgtcgcga cgagcaggac cggcagcacc gcgagcccgg ccacggccag cttcgcgtcg
     7441 atgaccagca tcgcgaccgc catgccgagc accgtcgcga agttcaccac ggcgatggtc
     7501 agcccgctct ccacgaacgt ggacagcgcg gtcacgtcgg tggtcatccg ggtcatgatc
     7561 cggccgcccg gctcacgctc gtagtagtcc agtccgagcc gctgcaggtg ccggtagctg
     7621 cgcagccgca gcgcgaacag ggcgctctcg ccggtgcgcg tggtcacccg gggctgggcg
     7681 cgcaggacga accagttcgc ggcgacgatc agcagcgcga ggccggagac ggccgcgatg
     7741 tcggtcatgt ccccgttgac cacgccccgg tccatcccgg agcggatcat cgcgggaagg
     7801 acggtgacgg cgagcgcgtc ggcggctacc agcgcgatgg ccacggccag cagccggcgg
     7861 accggccgca ggacccacca caccccggcg gatcggtcgc cgccgccgga cgcggcgccg
     7921 gtcccgtttg cggtggcatc ggcccgaggc tcgggctcgg atcgcttctc ggccaggcgc
     7981 gggtcgggcc gatccgtggc ggccgggagg cggcggatcc gctcccgcag ctcagggagg
     8041 tccacgttgc cgggcagccc accggcatga tcgaggtccg cgccttcggc cgcaccggtg
     8101 tccggccaga gcagggccgc accgggcgcc tgttcggtcg cgcccgtcac gggcgtgcgt
     8161 tcgtcgatcg actggtccgg cccggccagc agctccgcga acagcgggca gcgggtcagc
     8221 agctcctcct cggtcccgac gtcgacgacc ctgccgccgt cgaggaccgc gatccggtcg
     8281 gccagcccca gcgtggagcg ccgatgcgcg atgagcaccg tcgtccggtc ggccgtcacc
     8341 tcccgcagtg tggcggtgat ggccgcctct gtggcggtgt ccaccgccga ggtggcgtcg
     8401 tccagcagca gcacacgcgg atcggacagc agggttcggg ccagggcgac gcgctggcgc
     8461 tggccgcccg agagcgtcag cccgcgctcg cccacccggg tgtcgtaccc gtcgggcagc
     8521 gccgagatga acccgtcggc gcccgccgca cgcgccgcgg cccgaatctc ctcacgtgtc
     8581 gcgtccgggt ggccgtaggc gatgttgtcg gcgatcgagc aggagaacag gaacggctcc
     8641 tcgaacacca ccccgaccga ttggcgcagc gagcgcagcc gcgtgcgccg aatgtcgacc
     8701 tccgcgccgg gcggcccgat ccggatcgcg ccgtcgtcca cgtcgtagaa cctggggatg
     8761 agcagggaaa ccgtcgactt gcccgaaccg gaggggccga tcaccgcgac cgtctccccg
     8821 ggctcgaccc gcagcgacat gccctccagc accggttcgt cacgcgtgta gccgaaacgc
     8881 acgccgtcca gctcgacccc gatcggtccg tcgtcgggca cgtcgacggc gtccggagcg
     8941 tcgccgatgt cggaccgcac gtcggtcagg tcgtagacgc gctcggcggc cgggcgcacc
     9001 agctgcgccg tgatgaccag gttggacagc actccggatg gcgcggtgag cgtgaccatg
     9061 tatcccgcga acgccacgag cgtcccgatg gtcacgtcac cgcgcagcgc cagccagccg
     9121 ccgagcagca gcaccgcgat ctgtccgacg taggggagca cccccagcgt ggcgctcggg
     9181 gtggcctgca tacgggccac ccgcatccgc tcgccgaaca gaagacgggc ctgctcggtg
     9241 aggcgatcgg tttcgcgccg ctcctgtccg aagcccttga ccacgcggac cccggtcacg
     9301 gtctcctcga tgtgctgcgc gatctcggcg gtgcgctgct gcaccgccca cgtcgccggg
     9361 aacatgcggc cgctcgcccg cacggtgacg accacgaaca gggcgagcac gaccagcgcg
     9421 atcacggtca gcggcggcga gagccacagc atcgcggcca gcgatgccac gatgagcacg
     9481 ccgccgccga gcgcctgcgg cgccatcgac agcagcccct gcaccagctg cagatcgatg
     9541 ttggcacgcg acatcacctg cccggtgcgc agcgcgtcct gctttccgcc gtccagccgc
     9601 tgaacggagg cgaacgcggc ggtgcgcagg tcgtgctgga cgctgagggc gagcttgccc
     9661 gccaggaact ggcgggcgaa cgaccccgcg aactgcagca ccgccgccgc gagcagcagc
     9721 gcgatgaggg cgccgatgtg gtcgacgcgt ccggcgaccg cgccgtcgat ggccacctgc
     9781 gtgaccagcg gcccgatcgc tcccagcccg gtccccagga cggcggcgag gacgacggcg
     9841 ccggtcagag cgcggtgccg caggcagctg cggagcaggc gggtggtcca gcgcgcccgg
     9901 aagggggtcg ggcgcgctgg accacccggc gtggcggacc gctcagccga cggcccggtc
     9961 gtcgacgccg ccgacgtcat cgacgccttt cgggcggcca ctaggccccc gcggtgatcg
    10021 gggtggcgag cacgagctgc tcccacacgg gggtcacgcc ggtggccgtg tacagcagag
    10081 cgagggccac gcccgcgtcg ccctccagga acgacgcgtc gcgcaccatg ccctcggggc
    10141 cgaagtaggt caggtgcccg gcggcgcgct ggtcggccag atagcgcacc caccggtcgg
    10201 cgaactgccc ggccccggcg atgccgaagc ggtccgacat gtgtcgtccg aaccagcaca
    10261 gtccggcggc gccgtggcag acgcatccgt ccatgacgcc gcagtcgccg tcggggcggg
    10321 cgatgaccgc ctccgctgtc cggcgggcgg ctgacgcggc cccgggcgac cccgtggcct
    10381 gggcggcgac cgacagcgcg agggcgaccc cggggtcccc ggagcaccag gtcgcgcggg
    10441 agggggcgta gcgcatctcc acccggtgcg ggaagaccga gccgttgacg tcggacccct
    10501 ggctcagcag ccaccgcagc gcgtcgtcga gcagcgctcg ggcgcgcggc cggaccgacg
    10561 tgtcggagcg cgacaccgag gccaggtagg agacgagccc ggcggcgccg tgcgccaccc
    10621 cgatgatgcg gcacccggcg gactggtcgg cgcggcgcgc ctctgagtcg gcgaggcgga
    10681 agaacaggcc gttctcgtcg cgctcggtgc ggttctcgat gacgtcgagg atgcccgacg
    10741 tcagcttctc ccggaagctc gcctccgggt gggccaggcc gtagacgccg agtccgagca
    10801 ggcccatggg caggtcgata tcgaggtcgt cggggaacgc ggtcgcccac tgcagcacga
    10861 tgtcgtcgat cggggccaga ccgctcgcct cggttccgtg ctgccgggcg agctgaatcg
    10921 cgacccatcc ggcctgcgcg gcgccgcggt acagccacgg gccgacgttg gacgcggacc
    10981 gcagcagccc catcgcctcc cggaaggagt cccgcgccgc cgtgctcggc gccccgtcgt
    11041 cgccgagggc ccggcggaac tccatcgcgg tcagcgcgtg atcgagcagc agggtgaagt
    11101 cggggtcgcg cgtgatgctc tcggtggcat cggcgtacag cgtccgggcg agccccacct
    11161 ggtcttcggc cgcggtcatc atgccttccc tcccacgccg tccaacgctt gcagctggtg
    11221 gatcctgcgc tcggccagct cgtaggccag gtactccaga cggacggcgt cgaaggcgaa
    11281 cagccggttg cagtgcaggt gaagtgcgga cccgaacacc gaccagccgc gacggccggt
    11341 cagggtctgg cggaccgagg aggagagcgc ggccagcgcc ttggcgacct gctcgtctcc
    11401 ctgggcgtcg gccagatggt cgcgcagtgc ccggtcgtgc gcgcggtgga acttgcccag
    11461 cgggttgccc ttcttggtga aggagaggga cgtgccgctc tggcagaggc ggaggaacgc
    11521 gcgctgctcg tcggtggagt cgaacagcgc cgagcaccag ccgaccgcgt cggccaccgc
    11581 ctggtacagg cgcagctcct ccgtggggcg ggcggccagg aaagccgcca cctggtcgct
    11641 ggaggcggtg aacaggcgct cggccgcggc caggttgtcg gcgccgccgt agcgggacac
    11701 ctcgggaatg tagtcgtcca tgaccgaccg gccgatgagc ccctcggcgc ggagcgcgcc
    11761 gccgagcgcg tccatcgcgg cgacgacatg ggcgcgcgcc gctccgtcga tgggcctcat
    11821 ccgcacccgc acgtggtagc cgccgtcggt gtagcggagg aagaaccagt cggtgaccgc
    11881 accggagcgg tggagctcgt cggcgagctg cttggcccgc gtgacgacgg cgtcggcgga
    11941 ggcctgcccg cagaagtagg agaagtacac ccacgctcgg ccgcggtcgg cgtcgaaggc
    12001 gtcggctccg gtacccggtc ggggcggggt gcggtgaacg gggctgaagg ggatgacggc
    12061 ctccgcgacg tggccgccgc tcggcccccg cacggccggg gcctccagct gcggcatctc
    12121 gatgatcttg acggacgcgg tgtccggccc cttggcctcc ttggcgagcg cggcgcccac
    12181 cgaccgcgcg gaccttaggt cgatcgggag cacgtggtcg tagtcgccga cccccaccca
    12241 gcggcggtcg cccaggccgg ggaggagccg acgcaggtgg ccggcggggt cggggtcgtg
    12301 caggacgtcg cggatgtccg cgcgcgccag gcgccactgc tccggtgcca cgacgaccgg
    12361 accgcaggtc acccggggca ggtgggacag gtgcgccagc gccccccacg accagccgac
    12421 accgccggag gaggcgaggt ggccgaggac cgcgtagacc gggtcgaggc cgtggaagtc
    12481 gacgttgtga gcggtgttga gctctaccag gacggggcgg ccggtcaggg agtcgcggag
    12541 gcggaactcg tcgccgcgca gctggatcag cagccggtcc agggcgaggg ttccgccgga
    12601 ggcgccggtc agcgcgatgg tgtcgtcgag gaggcggggg cggatgagga cattgccgat
    12661 ccggccgccg gggtggtaga cgagctcggc gtggatgggg gcggtgtccg gggcacccgc
    12721 cgtatcggcg tcggcggtcg cgttcggacc ggtcgggacc cccggtccga acacaccggg
    12781 cgcgtcggag ggggcgcccg ccgccaccgc gtcgcccacc atctcctccg cgccgtgcac
    12841 cgcgtcggac agccgctgcc gcatgccgtc gcggttcagg ctgaagcggg cgagcagcgc
    12901 gtgcggcgcg cggccgacac cgccgacgag catgctgtgc aggccctccg ggtggtcgcc
    12961 gaggaggacc gccagcgccg cccgggcgcc ggtggtcgaa gcggcgggcg tgtcgtttgc
    13021 gcgctcatgc tcctcgctcg ctgtaccgcc gacgctgtgg ggcctgcggc cgttgggcgt
    13081 cgacgctttc gctcgttcgt tcgcgttcgc gtcggtgttt tctgcgcgct catgctcctt
    13141 actcgctgta ccgccgacgc tgtggggcct gcggccgttg ggcgtcgacg ctttcgctcg
    13201 ttcgttcgcg ttcgcgtcgg tgttttctgc gcgctcacgc tcctcgctcg ctgtaccgcc
    13261 gacgccttcg ggcctgcggc cgttgggcgt cgacgctttc gctcgttcgt tcgcgttcgc
    13321 gtcggtgttt tctgcgcgct cacgctcctt actcgctgta ccgccgacgc tttcgggcct
    13381 gcggccgttg ggcgtcgacg ctttcgctcg ttcgttcgcg ttcgcgtcgg tggggatgtc
    13441 gaccggtgtg ccgtcgcgcg tccaccggtc gtagagcttc agcagctccg ggttgacccg
    13501 ggggagcgag gattcctcag gggctcggac accggcgttc acggccagct cggagaccga
    13561 ccggtgccat gagcgcagga cgcccgactc caggtcgagc gcgctgagca gcggcacctc
    13621 ggcgtcctcg tagcgcgccc gaaacgcgtc gcggaactcg tcgatgctga acgccgaacc
    13681 gccggccgcg ccgccgccgt tctggagtgc cgccacgcgc aggatcgccc gctgcaggtc
    13741 gtcgctcgaa cggcggtcga gtgtggccgc ggacatgtcc atctcggggt ggacatcgaa
    13801 ccgctgagcc tgcttgacct ccgcgaacga tggaatgtgg gatgccgccg cgcgccaccc
    13861 cgcgtcgagc gttccggtga gggcggggtc caggggacgg accccggtcg cgtcggcgag
    13921 cagggtgcgc agtgcgtccg cctgttcggt ggcgcccatg gcctccagga ggtcgacggc
    13981 gcgttccgcg ggctccacgc ccggctcgat cagtccgagc gaccgctcga tgaggccgcc
    14041 gtccaccagc cgggtgagga atccggccat ctggtcctcg gagaacccgg gattgtcggc
    14101 ccgcagcgcg gcgacgatgt cggcgccgat gacctcgccg tcgccgagga cgcgcaggac
    14161 cgcggcgatg gccggggtga ggcgcatgct gacgacgtcg gcgctcgcgt caccggactt
    14221 cgcgaaccgg aggacgtcgc cgtcggcgcg ggctatcggg ttggtgcgca gcggccactg
    14281 cagcgggccg accgcgtcgg ccgccgcgcg gacggcctcc tccagcgcct ggacgtcgac
    14341 gcgcacccgg acacggtgcc ggtcgcgtgg ccccagcgcg aggtcgcgct cctcgccgac
    14401 ggagacggga gccgtaccgg cgaacaggcc gtagggtgtc gcgcggccgc ccatccgggc
    14461 caggtagcgg gcgagggtgt cgcgggcgcg ctggtcgccg gagacggccg cgtcgcgtac
    14521 gtaggggcct gcggccaggg agaccgccat ggtcgcgatg gggtccgcga cgtcctcgtc
    14581 ggccaccatc cgggcggcct cgtcgacact gaacagcggc acgcgcagca tgccgcagcc
    14641 ttcggtactc agcgttcctc ccctcccgtc gccgctcggt cggccggtcc ggccgacctt
    14701 gggcggccgc ccaagcgctc cgcgaccagc ccgaagatct ccttcagcgc acgcaggtgg
    14761 tcgtcggcgg agcgggacat ctcggtgatg acgacctcgt ccgcgccggt gagctccaga
    14821 agcttgcaga ccgcggcggc gcactgttcc gcggtgcccg cgcaattgac ctttattccg
    14881 gcgcgaatac tgtcggtgcg cgcgatgacc ggatcatcat tggctaccag tgccgcggcg
    14941 acggcggtgc gtccgttggg aaaggcggcg cggtaggaat tgagtgtgcg tgtgcacgcg
    15001 tccacatcga cattgaagaa aagggcgtgg cagtaattga atcccatttc tccggcgagt
    15061 tcggccgagc gggtccccgc tccgtgcagc cagcgctcgt agggggtgtc cagcggatcg
    15121 atccagtcgc ggccgtcgtc caggaccgaa acgacggtgc ggatggcctc gtcggtcgcg
    15181 tcgccgccct tgcggaggta ggcgagcgcg tcggcggcgc tcccggcgac gtcgccgcgg
    15241 ccgaatccga cgtcgagccg gtcgccgcag aagaaggcgg cggacgcgac gtcctcggcg
    15301 gtgaggtggg ggtcgcggac gcggatgagg gtgacggcgg tgccgatgcg gatgcgcgtg
    15361 gtgtggctgc ccagcacgcc cgcgaggagg agggggttgg ggctcggcac gccggtgctg
    15421 tggtgttcgg gcagccagag ccgctggtat ccgacctgct cggcgaggag agcggcctcg
    15481 aaggcggtct cgcgcttggc gcgcacggag cggtggtcgc cgaggtcgag gtattcgaga
    15541 aggccgaggg gcggcggtgg atccgcgttc gcgggtgtgc gggcgggtgt ggccgtggcc
    15601 gtcgccgagg ccgccgtcgg cgtcgtcgcc gtcgtcctgt ccatgccgat ctccatccgc
    15661 aacggcgggc cgtcccgcct ggggcccgag cggcgggtgg cggccgttca ccggtcggcc
    15721 gccacccgcc agggagtgcg cggacaagca ccgccgcact catccctctc ggacacgcgg
    15781 ccgggtacgc accgggcctc gcgtccatcg acattccgcc tcgttcacga ggaacgagag
    15841 ccggcgtgta ctagcaggag acggtgttgg cgctcgggca cgtggtgccc cagcaggtcg
    15901 tgccgagggt gatggggccg cgggcgtcga tgttgttcgc cgagagctgg ccgccaccgg
    15961 gggtggagaa ggtctccatg tcgatgtcga ggtcgaattc gacgttggcc ttggcgttag
    16021 gagcagtcat aattgcacct tccgattaag ggatgcacgg ctgaggaata ttttttatgc
    16081 cgtgcagagt tcaccctagg ggtgggcatt ccaatgccgc ttcggtccga ggaaccattt
    16141 cgctgccctt ccgacggatc ggtccgtaaa ggtacgtgag ttgggggtcc tcccttcgga
    16201 ggagcggcgc cttcggcggg gcccgcgggt gcccggtggt gtcggccact ggggggattc
    16261 ctggtcacat gacctctatg cggcgttcag gcaggttcaa actttcctca agcagggacg
    16321 gacggtgtta gatcgtcact ctcaggaaac aagtggatgc gtagggttat atccacgcct
    16381 tggggggata cgcatgacca cgcctgtctt cgagcagacg atcacggggt actcactgcg
    16441 cagcgcgcac gggctcgcac aggcctcgca gctcgcttac caggacgagg accagatcaa
    16501 gaccacaacg gccgtgtggg ggatgcccga gtgccggttc ttccaggtgg agttcgagca
    16561 gccgttccca atcgatgaca cccaggccta tgtcgcggcc aacgacaagg tggtcgtcgt
    16621 cgccttccgc ggcaccgaac tggcgcagtt gcgcgactgg ctctccgatg ccaacggcct
    16681 cctggccccg gacccgaacg gccagggcat ggtgcacatg ggcttcaacc aggccctgga
    16741 cgcggtgtat ccgcaggtcc tcaacgccgt atcggagatg cgcggcaacg gccagtcgat
    16801 ctgtatcacc ggtcacagcc tgggcggcgc tctggccatg ctggccgcgg cccggatgcg
    16861 tttcggggat tcccgcctgc tggcggacgg cgtctacacc ttcggccagc cgcgcacgtg
    16921 cgacccgctg atggccagaa ccttcgaccg cgagttcaag ggacgcatgt tccgcttcgt
    16981 caacaacagc gacatcgttc cccagctccc gcctgagccg ctctaccatc acgtcgacga
    17041 ggagaagtac ttcgacgccg acggtcggct gcgggagaag aagatgtcgc tgctgggcgg
    17101 cctcaccgac aaggtcaagg gccagacggc cgacccgatg gccctgggga cggaccagat
    17161 ccgcgaccac ggcatcgccc gctacatcgc caacctggaa aaggcgatgg gctgaccgcc
    17221 gcccccacca ccggttgccc gcccgagccg ttgccccacc cagtcgacga cggcgcgggc
    17281 gggcacgtta tgccagccgg gcacgtcccc ctcaccggcg tcgagtcgag cgatcgcggg
    17341 gccggtggtg gctcagccct cgctcgcgag ggcgcgccgg atctccgcga tgcggtcatc
    17401 gtcgaactcg gcgtcgggat cggcttcgag gaaggccgcg gcgagggcgc cgagcgccag
    17461 cccgggaagc gtccagtccg ccgggtcggg ggcgccgaac aggtcggccc ggaccgtctc
    17521 ctcggacagc gccggggtcg tcggagccat cacgaccagc ccgcgcacca tggcgttcgc
    17581 gagcgtcgcc agcgtctcga atccggtgct cagcgccgga cgcaggcgga ggccgagcag
    17641 ggacgccacg cgctcgtagg cggcggcgag gccggcggtg acgttgcgct ccgactcggt
    17701 gagggccgcc tgcacctcgg tgcggaggtc gccatcgggc aggctcagga aggtcgcgtg
    17761 cagcgcgacg taggtgcgcc attccggcga acgcaggaag gtctggagct cggccggggc
    17821 accctggcgc aggatctcgg tcgccagggc gatgcgcagt gacggggtct tcaaccagtc
    17881 caggcggtcg aggatggtct ggtcgaccgc gcgccgcgcc tccgggttct cctcgacgat
    17941 ggccgggctg gtgccgcgcg cgagctcttt cagcaggtcg ctgaagaaca gatccttgta
    18001 gggccagcgg cggtagacgg cgctgcggga cacgcccgcg tcgcggatca cgtcttcgaa
    18061 gctgatgtgt tccaggctga ccgtcagccc ggccctgttg acctggtcca ttgcggcctg
    18121 gagcatgcgt cgctcggtct cctggtcgct gagtcggcgc ctccgccgtg tcaggccagt
    18181 ggccgcttgg gagtccccgc ccatgttgca ccttctgcgc ttgggatatg atgtctcaaa
    18241 ttttgaatac caggatcaca gtctactaag cgtgacggat cgcgtaacca gcgaacggtt
    18301 gagcgcgacg agccgtgtaa ccagtgaacg gtccccgacc aggccgcggc cacgccattc
    18361 agcgcccaca cggccatccc acaccccagg ggggaagatg cgtgatcagg acaccgatct
    18421 caccgatgtc gccgagtccg acctgaccac acggcgcggc acgttcagag ccgtcgcctt
    18481 ccgcgatccg ctcgacggcc atgaacacat ggccctggtg ctgggggagg tcgtggaccg
    18541 tgaggacgtg ctggtccggg tgcattccga gtgcatgacg ggtgacatct tcggcgcgac
    18601 gcgctgcgag tgcggcgagc agctcacgtc ggcactggac gcgatcgtgc gggaaggcag
    18661 cggggtcctg gtgtacctgc gcggccacga agggcgtggg atcgggctgg tcgccaaggt
    18721 gcgcacgcac atcctccagg acgagcaggg gctcgacacc atcgattcgg ccacgtccct
    18781 cggcctgccg gtcgatgtcc gcgactacgg tccggccgca cgggtgctgc actacctcgg
    18841 cgccgcctcg gtccggctgc tgtcgaacaa ccccgacaag atcggtgccc tggaggcgta
    18901 cgggatccgg gtgtccgagc aggtgccgct cctcgccccc gcgcacaacg gcaacatcgc
    18961 ctacctcacc gccaagcgcg accggctcgg gcacgacctc cctcaggtcg aggaggtgtc
    19021 gagcgcgtcg ctgtgcgata gcggcgcccg cggccaggag gacggcggac gtggctgacg
    19081 tcgcgggcgc cgccttcgcc gccctgctgc ccgtcgctca agaagcgacg gcgatcgcgc
    19141 gacggatcgt gcgggagcac gcccccaggg cggtcaccga gaagggcgag cgcgacatcg
    19201 tgaccgacgt cgacctcgcc gtcgaggacg cggtccgtac gtttctggcg cgcgaaaccc
    19261 ccaatatcgg cttgctgggg gaggagcacg gacgcaccgg cggggcggac ggggagccct
    19321 ggtgggtgct cgacccggtc gacggcaccg ccaacctcgc gtgcgggatt ccgctgtgcg
    19381 ccgtctccct cggcctggtg tgggaggggc gggcggtggt ggccgtgatc gacctgccct
    19441 tcctcgacac cgggtacacc gccactgagg gggcgggtgc cttctgcgat ggagagcgca
    19501 tccgcgcctc cgggcacagc gcccccgccg atgcggtggt ctccatcggc gacttcgccg
    19561 tgggggaggg cgccgacgcc aagaacaggg tgcgcctcga cctgctgggg cggctgggcg
    19621 cgcgggtgcg gcggatccgc atgctcggta cggccgcgat cgacctcgcc tggaccgcgc
    19681 acggcaagct cgacgccgcg gtcatcctgg cgaaccggcc ctgggacacg gcggcggggg
    19741 ttctcctggt ccgggaggcg ggcggtgtgg tcctcgaccg cgatggcagc ccgcactcgg
    19801 tggactcctc ggcgaccatc gccgtcgcac cggggctccg cgagcacatc atgttggagg
    19861 tggcgcacgc gtatgggatc gagtgacgca cacgctgccc cgctgtccgc gggcgtccgc
    19921 ttccgagtca cgtccgcttc cgcgggtccc gccgtcggcg ctgccgcgca ggcggccctc
    19981 ctggccgtcc tcgccgcggc cgctggcctg ggagctgcgg gctggatcgc cggatcggcc
    20041 tacgcggtgg ccctcggggg actgctcacg cgcgccctgt accgggacgg acacccgggg
    20101 atgcggccgg ccgaccgcgt gaccctggcc cgcgccgtgc tcgtcggcgg ggtgatggcc
    20161 ctcgtcgccg acgaggttgc gggccggccg ctggacgggg gcgcgctcgg gaccctggtc
    20221 ctcctcgccg cggtggcact ggcgctcgac ggcgtcgacg ggctggtcgc acgccgcacc
    20281 aatacgacca gccggctggg cgcccggttc gacatggaag tcgacgcctt tctgatcctg
    20341 gtgctcagcg tgcacgtgtc cctccacctc ggtgcgtggg tggtggcgat cggcgcgatg
    20401 cgctacgcgt tcgcggcggc ggccaccgtg gcgccgtggc tgcacggcga cctgccgctc
    20461 agtaccgccc gcaaggcggt ggcggtggtg caggccgccg ccctcatcgc ggcttcggcg
    20521 agcgtgctgc cgcactcggc ggcaacggcg gtggtggcag cggcgctggc gctcctcgcc
    20581 tggtccttcg gccgcgatgt gtggtggctg tggcgaacca ggtcggcgcg gctacgaacc
    20641 ggcccggaca cggacaggga gggctgatgg agcacaccgc gcgcgccttc tggctgcggt
    20701 caccaggcgt aggagagatc cggtcggtcc ctgtcccaga gcccgcaccc ggcgacgtgg
    20761 tcgtccgcac gcgctacacg ggggtcagcc gcggcaccga gtccctggtg ttccgcggtg
    20821 gcgtccccga gagccagcgc gaggccatgc gggcgccctt ccaggagggc ggccttcccg
    20881 gcccggtcaa atacggctac ctcaacgtgg gcaccgtcga gcaggggcca tccgagctcg
    20941 tcggacgcga cgtcttcagc ctctatccgc accagacccg gttcgtcgtt ccggccggcg
    21001 cggtcgtgcc ccttccggag ggcgtccccg ccgagcgggc cgtgctggcg ggcacggtcg
    21061 agacggcggt gaacgcgatc tgggacgccg gaccgctcat cggcgaccgc gtcgcggtcg
    21121 ttggcgcggg aatggtggga tgctgcgtcg cgcgcctcct cgccgacatc ccgggcgccc
    21181 gcgtccagct cgtcgacacc gaacccgagc gcgccgacgt cgccgagtgc ctcggcgtcg
    21241 ccttcgccca cccggcggaa gccgcgggcc agtgcgacct ggtgttccat gccagcgcca
    21301 cggaggcggg cctcgccacc tcactggacc tgctcggaga tgagggccag gtcatcgagc
    21361 tcagttggta cggggaccgc gaggtccgca tcccgctggg ggagtccttt cattcccgcc
    21421 gactggcgat tcgcgcgagc caggtgggcg tggtctcccc ggcgcgcagc cgccgccgat
    21481 cgctcgccga ccgcctctcc ctgtcgctgc ggctgctcac cgaccccgcc ttcgacacac
    21541 tgatcaccgg cgaaagcccc ttcgagcgac tgcccgatct catgccgctc ctcgcggatg
    21601 gccggatccc ggccctgtgc catcgcatcg cctacggata gggcgcgcgt ccacctggag
    21661 aggtcagtga cggccccgga ccgacgtcca ccctttgtaa aggagccctt ctcgtgttca
    21721 gcgtcaccgt ccgcgaccat ctcatggtcg cgcacagctt ccgcggtgaa gtcttcggac
    21781 cggcgcagtc cctccacggg gcgacattca tcgtcgacgc ctcgttccgc cgacccgaac
    21841 tcgacgacga cgggatcgtg gtcgacatcg ggcgagccac ccaagaactc aactccgtcc
    21901 tcgccgacct caactaccgc aacctcgacg aggtgcccga gttcgccggc gtcaacacct
    21961 cgacggagtt tctggccaag gtcatcgccg accgcatcgc cgaccgggtg gcacagggcg
    22021 cgttggggga acaggcccgc ggggtgaccg agctgaaggt gaccctgcac gagtcgcaca
    22081 tcgcctgggc gagttacgaa cgtgcgctgt gacagcgccg accttcgtcc tgcccggcgg
    22141 cgtggacgac cccaccacgc ccagcggagg caacgtcttc gaccgccgcc tctgccggga
    22201 actcgcgcgc atggggcggc cggtccgcga ggtggcgatc ccgggcacgt ggccggaacc
    22261 ggacgcctcc ggccgggatc ggctggcgcg ggcactcgac gctctgccgg acggcgccgc
    22321 cgtggtcgtg gacgggctcg tggcctgcgg tgtccccgag atcgtcgttc ccagtgcgcg
    22381 tcggctgcga ctgggggtcc tggtgcacct gcccctggcc gacgagacgg ggctcagcac
    22441 cgatcacgcc gccgagctgg acgccgctga gcgggacacg ctgcgcgccg cgcgtgccgt
    22501 catcgcgaca agccgttggg cggcgcgcaa catcaaggat cggcacagcc tggaccatcg
    22561 ccgggtgtgg accgtggaac cgggcaccga cgccgcgccg ctcgtgtctg gaacggatca
    22621 cggtgttcgg ttcctctccg tcgcgtcggt gaccccgcgc aagggacatg acctgctcgt
    22681 gcgggctctg gcggggatca ccgacctgcg ctggggctgc gtctgcgtgg gaccggcacc
    22741 gccggagtcc gcgttcgcca gcgaagtacg tcggctcgtc ggacagctgg gactcggcgg
    22801 aaggattgac ttctccgggc cgctgtccgg agacgcgctg gcgcacgcct acgcggaggc
    22861 cgacctcctg ctgctgccgt cccgcgccga gaccttcgga atggccgcgg ccgaggcact
    22921 ggcacgcggc atacccgtgc tcgcgaccac ggcgggggcc ctgccggaca ccctgggaca
    22981 ggcacgcggt ggcactgttc cgggtctcct cgtcccaccg aacgacgtcc aagcactggc
    23041 ggggtcgcta cggagctggc tcatggacgg ggcgttgcgt gatcggctac gggcggcggc
    23101 gcggcttcgc cgggccgaac tacgcccctg ggaggcggcc gcacgggata tgaccgtcat
    23161 cctcgaccga atgcacgagc cgcgccaccc acgaccccaa agggagaatg cctggtgagc
    23221 gcccccggat cgccccgctt cgaagccgac tggttggccc tgcgcgaggg ggccgatgcc
    23281 gacgcgcgcg acgccgggtt gctggtcccg ctccgcgcgc atctcgcagc ggagcatgga
    23341 cggcggcgcg gcggcagcct caacatccac gacctcggaa gcggcaccgg atcgatggcg
    23401 cgctggctcg ccccgctctt ggacggtccc cagcactggg tcctccacga ccgcgacccg
    23461 gaactgctcg agcgcgccgc cggcttcccg ccggagccgg cagcggacgg cgcccccgtc
    23521 accgtgcgaa cccgactggc cgacctgacc gaactggatg cggtcgacct caagggcgcc
    23581 gacctggtaa cagcgtccgc gcttctcgac ctgctcaccg cagatgaact gaacggcctg
    23641 gccgaggcgt gcactggcgt tggatgcccc gtcctgctga cgctgtcggt cgccggacac
    23701 gtggtcttga cccccgatca cccactcgac gccgatatcg ccgccgcgtt caacgcccac
    23761 cagcgtcggg aggtgcaggg gcgccgcctg ctcggcccgg acgcgcccga cgcggccgcg
    23821 cgggcattcc ggcgccgcgg tgcgccggtg tacaggcgat caagcccgtg gcggctcggc
    23881 ccggagcagc gccggttgat gcggcagtgg ctggaggggt gggtcgccgc cgctgtcgag
    23941 cagcgcactg aactctccac cgaggcgcgt acgtatgtgg agtggaggct gggcgagtgc
    24001 gcgtccggcc gcctgcgagc cgaggtgcac cacgtcgacc tgctcgtcct cccggatggg
    24061 ccagcggcgg aaggtaggca cgaggagcgg tcctgatcga tgatgggtgg agatcctcgc
    24121 tcggagtcgt gtccggtgga ttggcgcgcg acgacagtgg gaggcgaagg tcgtgcgggg
    24181 gcaactgcag ccgaggcgga ggccatggtg ggacgccacc gtcaaggggg tcgtctggcc
    24241 atgggcgcgg gtgctggccg ccgtgacgct gctggccgtg ctcgtgtggc ggctcgacac
    24301 agatgccctg gcgggggtgc tcggctccgt gggcggagcg gaattcgcgg tcgcggcagc
    24361 cgcggcactc gcgatcggag cggtgacgac cgcactcagc gcgtggcggt ggcggctcgt
    24421 ggcccgggcg ttggggctgc ggctgcggat ggggcgggcg ctcgccgact actaccgggc
    24481 cctgctgctc aacgcactac ttccgaccgg agtcctcggg gatgtccaca gggctgtgga
    24541 tcacggtcgg tcgtccggcg atatcggcca gggggtccgg gcggttctcc tggagcgggc
    24601 ggccggtcag gcggtccttg tcggcgcggg g
//
