LOCUS       NZ_NDXL01000003        13461 bp    DNA     linear   CON 27-APR-2024
DEFINITION  Streptomyces kasugaensis strain BCRC 12349 scaffold3, whole genome
            shotgun sequence.
ACCESSION   NZ_NDXL01000003
VERSION     NZ_NDXL01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces kasugaensis
  ORGANISM  Streptomyces kasugaensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 2433044)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Comparative genome analysis for kasugamycin overproduction
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2433044)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Comparative genome analysis for kasugamycin overproduction
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 2433044)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030,
            China
REFERENCE   4  (bases 1 to 2433044)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. May-2015
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 188.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002261115.1-RS_2024_04_27
            Annotation Date                   :: 04/27/2024 02:42:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,951
            CDSs (total)                      :: 7,863
            Genes (coding)                    :: 7,657
            CDSs (with protein)               :: 7,657
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 206
            CDSs (without protein)            :: 206
            Pseudo Genes (ambiguous residues) :: 0 of 206
            Pseudo Genes (frameshifted)       :: 87 of 206
            Pseudo Genes (incomplete)         :: 170 of 206
            Pseudo Genes (internal stop)      :: 23 of 206
            Pseudo Genes (multiple problems)  :: 65 of 206
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:37:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1958368
            Orig. end                         :: 1971829
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NDXL01000003.1.
            Bacteria and source DNA available from BCRC.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..13461
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="aminopolycarboxylic-acid"
                     /region_number="7"
                     /rules="(AesA and AesB and AesC)"
                     /tool="antismash"
     cand_cluster    1..13461
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(AesA and AesB and AesC)"
                     /kind="single"
                     /product="aminopolycarboxylic-acid"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13461
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8461](+)"
                     /cutoff="10000"
                     /detection_rule="(AesA and AesB and AesC)"
                     /neighbourhood="5000"
                     /product="aminopolycarboxylic-acid"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8461
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(AesA and AesB and AesC)"
                     /neighbourhood="5000"
                     /product="aminopolycarboxylic-acid"
                     /protocluster_number="1"
     gene            complement(198..1043)
                     /locus_tag="B7024_RS37680"
     CDS             complement(198..1043)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010987023.1"
                     /locus_tag="B7024_RS37680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_052859861.1"
                     /transl_table=11
                     /translation="MSAATVSDGRRRRRARPGALLRTAPAALLVLAALAGPLLAAEPVD
                     KPVTAPYGEAGADALLGGDQLGRDVLSRLLHGGGALIAGALTVAAVVTLLATLLGCFAA
                     VSPRTGRLVERAADTAILLPPVLGIMLLALAWPGGGRLAITVAAIVLGTPYAVRIVAGA
                     AAPLAATGFVEAAVASGERVGHLALREILPNLRATVLALFGLRFVDAVYVISMAGFLQL
                     GPQPPEADWALMIRENAPGILLNPWAVVAPALAIGLLAIGVNLATDALAPAAARKAALR
                     "
     gene            complement(1040..2050)
                     /locus_tag="B7024_RS37685"
     CDS             complement(1040..2050)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018546193.1"
                     /locus_tag="B7024_RS37685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_052859862.1"
                     /transl_table=11
                     /translation="MTDTTAPPAEAAARPVTASAARRAGTLAARVAAVLAKRLVMLLVL
                     LAVVFAAIELLPGDAASATSERGEGTAGLAARRHLLGLDRPVWERFRDWITALPTGDLG
                     TSARGQHVTDLLAAPLPNTLLLGGTAFVLTVLGALALGIWAAARPRGAVDRIVDLTSTA
                     AFALPEFVVSIGLLLVLSLWTGWLPAATVTGADGAPATWTMLVMPVLALAVPQTGWNTR
                     IVRAALADQAAAPHVEAARLDGLSTSRVLLRHALPGAWPAIATGVATSTGMLLGGAVVV
                     ETLFNYPGIGTVLAGAVADRDTPVIAGVVACAAAVITVVLLLADLVRARTLGARS"
     gene            complement(2047..3591)
                     /locus_tag="B7024_RS37690"
     CDS             complement(2047..3591)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006138034.1"
                     /locus_tag="B7024_RS37690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_094795313.1"
                     /transl_table=11
                     /translation="MDWNRRQVLWAGGGMGAAALLAACGGGKDAASSGSGGTPQKGGTL
                     RVGALGRASAITRDPHGNQGNESDYLVIALVYDTLTAPGLKQNTVGRLASAWKPSADLK
                     TWRFTIAKGATFHDGSPVTAEDVVWSLRRLRNTPAGAARLPGITADHITADGKDTVVLV
                     SDFANAELPMITRLSTFILKKDTPDKDIAKAPGTGPFKLDWYRGGNARLLRNEHWHGGP
                     VPLDAIEVTMFESPQAMANAMLSGQIDLASNAGAVAARTADARKDIQVIRRPNDMAMPL
                     VMRTSGGPFADARVREAMKLIVDREAMVKQVLSGYGTVANDILGTGDPGYAKNIPQRTR
                     DLAKAKQLLTEAGFDFGKTYQLVTTEDIAGLAESATLFAAQAREAGVKVEVVKQESGTF
                     YDKTWLKGDLYTNYWGTNDSVVFFASKTMTTGSGQNEAGWSDKDFDAAYHKAIATGAPE
                     ARTAALRDLQQIEHDRSGYLLWGMADGIDLAAPKVHRLPQLPGYGRVQLENVWLSR"
     misc_feature    3606..3620
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.72"
                     /tool="antismash"
     misc_feature    complement(3622..3640)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.57"
                     /tool="antismash"
     misc_feature    3639..3654
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.49"
                     /tool="antismash"
     misc_feature    3648..3662
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.04"
                     /tool="antismash"
     misc_feature    3788..3806
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.02"
                     /tool="antismash"
     misc_feature    complement(3793..3811)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.25"
                     /tool="antismash"
     gene            3981..4976
                     /locus_tag="B7024_RS37695"
     CDS             3981..4976
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091641.1"
                     /locus_tag="B7024_RS37695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_052859864.1"
                     /sec_met_domain="TauD (E-value: 1.4e-09, bitscore: 35.0,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTGTAPVRPLDTAGAEELRRAAEQIHTEFGTSATSPGLLARVAE
                     SAAGLSEPVRHQLRPVDTDDGLFVLRGLDVDDDEIGPTPAGWAAAGDSAAVHDIVLLLL
                     ATVMGNPLAWEGQQDGRFVHNIVPAPGHETEQTGASSTVLLSPHTEDAFHPGRAHLLML
                     GCLRNHDSIATTAAGIRKAELDEADIALLSRPLLPILPDDAYTGARDFDGGHPPAVPTL
                     FRAEDGLTLRFDPAYTPVADAPPAHRAAYQRLSDELARVSVAVSLRPGEVLIVDNDLVV
                     HGRVPFRARYDGTDRWLKRASVRVPGRRTRPPAEAAEHGYGQAAVEAHAA"
     gene            5001..6032
                     /locus_tag="B7024_RS37700"
     CDS             5001..6032
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091640.1"
                     /locus_tag="B7024_RS37700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="WP_094795314.1"
                     /sec_met_domain="AesA (E-value: 2.5e-165, bitscore: 545.8,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETKNQAADAAPGIPADDTTLRILSTSDLAGIDITLTDVVDTVE
                     GAYRTLAAGRSDNPRKLTVRPADGHSVSYAMLGRDGSRNVVAFKTSYKNGLDKGRAEQH
                     YYTALTLYDDVTGLPVAMMDCGRIGALRTPAVSALLARECARPGARSALVIGTGTQGRL
                     ALPFLLTTLPDLTRLMLCGTHPEGIAAVREHLRTHFPDRDLEIVTDLRAAAGDADIILA
                     TAGGHTTAAVEADWLKPGALTVLVGHGLAPSTLHRADRVVATSEAQMKVTGTDMADASG
                     GFPAVDTEFPPVIAGVTAGRRSAEERVFAYNSGLVVTDIALGHRFAQLAIDQGLGQQVP
                     LWR"
     gene            6023..7405
                     /locus_tag="B7024_RS37705"
     CDS             6023..7405
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091639.1"
                     /locus_tag="B7024_RS37705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Y4yA family PLP-dependent enzyme"
                     /protein_id="WP_094795315.1"
                     /sec_met_domain="AesB (E-value: 5.7e-192, bitscore: 634.6,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 2.6e-20, bitscore:
                     69.7, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 7.3e-06,
                     bitscore: 23.1, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVTGPRTTDLPALPAHPDPETDQVLDSGLLHELSYAFGGPFHFL
                     LPHRFDANLTAFRTALRDAGVAGRVYYAKKANKAAVWLERCAANDAGVDVASAPELRQA
                     LGHGVRGEHLVVTGPAKSEELLRLAIRHGCLIAVDALDELDLLRALTGDGAGRPARLLL
                     RRLPPAQPHSRFGMPDAELTAALERCVRAGDAVRMEGFSFHLAGYATRPRADLAGELLD
                     WCLRARALGLPADRISIGGGFAVDYTSAGHWQTFLAGQRPEHYHARKTFRNADFYPYHS
                     PVAGAGALREILATVPANGHTTLAARLHETGTRLLTEPGRALLDTAGASVFRVQGVKDR
                     DGYRIVTVDGTSLSLSEQWFNSEYLPDPQLVTPAGRAHGDGVHPACVGGASCLDSDLLT
                     WRKIRFPARPRVGDLLVYPNTAGYQMDSNESPFHDLALPPKVVLDRLGARPRWRLDRRP
                     AL"
     gene            7436..8461
                     /locus_tag="B7024_RS37710"
     CDS             7436..8461
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006138038.1"
                     /locus_tag="B7024_RS37710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cysteine synthase family protein"
                     /protein_id="WP_094795316.1"
                     /sec_met_domain="AesC (E-value: 6.5e-176, bitscore: 581.3,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PALP (E-value: 1.9e-53, bitscore: 178.7,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEALARPAVVFRISELIGYTPLFELCRTETGSRLLLKLEMYNPT
                     GTAKIRMARQMVLDAEARGELRPGGRIIESTSGNTGLGLAVIAAERGYTFTAVVDHHAC
                     ADKLRAMRALGTELVYVAEDGTDELATAAREELAEDMARGQDNTVFTEQHNNLSNGIGY
                     FPVAHELHQALDGQLDVLIGAVGTGGALCGTARELRTLMSGVTVIGVEPKGSIAFGGPA
                     HDYYQSGTGTPEGAEIGALVDYDLIDEGVKVGDIEAFATARAVARTGLLIGGSAGGVVH
                     EALTRLPALPPGTTMVALVNDGGEKYLDTVFDDDWMNARNLLAPAVEREIDETLTKLRR
                     N"
     gene            8469..10025
                     /locus_tag="B7024_RS37715"
     CDS             8469..10025
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /GO_process="GO:0009410 - response to xenobiotic stimulus
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020548826.1"
                     /locus_tag="B7024_RS37715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MATE family efflux transporter"
                     /protein_id="WP_094795317.1"
                     /transl_table=11
                     /translation="MQLTILLRDSRALATLAVPLILTQLAQVALTTTDTVMMGLLGTVD
                     LAAGGLAIVIFNQLRTMGVGLVTSVGNQIAAASARAEAAQGSGAPDAGGAERDGADDPA
                     EGSGAGDPVESSGAGGPAESGGAGDPVGSGGAGGPAESSEEVRRIVRASLAVATLAGVA
                     GAVLMLLIGQALTPLGQEADVVDRAQTMLLALAPGLVPCLWFQAIRQFTVGMRRPQALL
                     QITLASVAVNAAVNWALIHGTWGLPKVGLPGVGVATSLVYLLSFLALYASAKRDEVLGP
                     LLSLNIAAADRATVRRLVKLGIPIAATYGSEAGFFSVTALMAGSFGSAALAAHTAVNQL
                     VYIVFQVAVGLSHAASINVSRELALGRTDTALRIKNTALACAAAVMAVVAVLYITLPHL
                     VLRPFFDTGGAKDAEAVAIATHLLLVIAVLQFFDCAQNIGVGLLRGLDDTKSGFRITLI
                     GYWVVGLPTAWLLGYAAGLHTLGIWLGLLTGLAVTAALLLRRYGTSLRARGAGQGVAAA
                     A"
     gene            complement(10778..11392)
                     /locus_tag="B7024_RS37720"
     CDS             complement(10778..11392)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539594.1"
                     /locus_tag="B7024_RS37720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="rhomboid-like protein"
                     /protein_id="WP_094795318.1"
                     /transl_table=11
                     /translation="MPWVAPLYVVAVGVGAYAAARLPGARRAELLRAHSTNVENLRAGR
                     WRTLVTSAAFIEEPLPLPYSAALLVALGTAEARWGPRRAAGVFAVGHIGASLLVYAGLR
                     GRVRADPPDATARAIDVGVSYGLNATLGALAMTVPHRGARTAATAGLLALGIRPVLRSE
                     RTFTDAGHLIAIALGVGIGAGRTPGTVIRAAVSMGSGPTGR"
     gene            11451..11810
                     /locus_tag="B7024_RS37725"
     CDS             11451..11810
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS37725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_094795319.1"
                     /transl_table=11
                     /translation="MDSGAAGGLDGGSDVGGGAAADEGLDAVGGFDAYRGLGLVEDFVV
                     AGNFGTTGDSGVDEDLGVDEDFGADGGFGADENRDGTQGELDAHREPETHRGLETHRKP
                     EAPRESEAVRELEAG"
     gene            complement(12114..12458)
                     /locus_tag="B7024_RS37730"
     CDS             complement(12114..12458)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS37730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_094795320.1"
                     /transl_table=11
                     /translation="MLAITVQTDTGPVHPRPADGEPSSLLGRFGGYDDQFAAPERGLGE
                     SQALTRIRRDGEGPFVAGAPAVCAAGDRPVSPDGARWIAAGPPVRWVGDPEQAVEAAGP
                     DWRKRLPEGV"
ORIGIN
        1 gccggagccg gaggggccgg tgagggccgt gaccgtgccg gcccgcacgg tgaggctgcc
       61 ggcgcgcagc aggaccgggc cgtcgggcag ggccacttcg agaccggtga cggtgaccgg
      121 cggcggggcg tcgggcaggt ccgtccggcc gtccgggggt atgcggtcgg tgggggtggc
      181 ggggtgccgg gtggtggtca tcgaagggca gccttgcgtg cggcggcggg ggccagtgca
      241 tcagtggcga ggttgacgcc gatggcgagc aggccgatgg cgagggcggg ggcgacgacg
      301 gcccaggggt tgaggaggat gccgggcgcg ttctcccgga tcatcaacgc ccagtccgcc
      361 tcggggggct ggggcccgag ttgcaggaaa ccggccatgg agatgacgta cacggcgtcg
      421 acgaagcgca ggccgaacag ggcgagcacg gtggcgcgca gattgggcag gatctcccgg
      481 agcgccagat gccccacgcg ttccccgctc gcgacggccg cctcgacgaa cccggtggcg
      541 gcgagcgggg cggcggcgcc ggcgacgatc cgtaccgcgt acggggtgcc cagcacgatg
      601 gcggccacgg tgatcgccag gcgcccgccg ccgggccagg ccagggcgag cagcatgatg
      661 ccgagcaccg gcggcagcag gatggcggtg tccgcggcgc gttcgacgag ccgtccggtg
      721 cgcgggctga cggcggcgaa gcagccgagc agggtggcca gcagcgtgac cacggccgcg
      781 accgtcaggg cgccggcgat gagggcgccg cccccgtgga ggaggcggct cagtacgtcc
      841 cggccgagct ggtcgccgcc cagcagcgcg tccgcgccgg cctcgccgta gggggcggtg
      901 acgggcttgt cgacgggctc cgcggcgagc agcggaccgg ccagggcggc caggacgagc
      961 agcgcggcgg gggcggtgcg gagcagggcc cccggccggg cgcggcgccg gcgccggccg
     1021 tcggacacgg tcgcggcgct catgagcggg ctcccagggt gcgggcgcgg acgaggtcgg
     1081 cgaggagcag gacgaccgtg atgacggcgg cggcgcaggc gacgacgccc gcgatgaccg
     1141 gggtgtcgcg gtccgcgacg gcgccggcca gcacggtgcc gataccgggg tagttgaaga
     1201 gggtttcgac gacgacggcg ccgccgagca gcatgccggt ggaggtggcg acgccggtgg
     1261 cgatggcggg ccaggcgccg ggcagggcgt gccgcagcag gacgcgcgag gtggacaggc
     1321 cgtcgaggcg ggccgcttcg acgtgcgggg cggcggcctg gtcggcgagg gcggcgcgga
     1381 cgatgcgggt gttccagccg gtctgcggga cggccagggc cagcacgggc atgacgagca
     1441 tggtccaggt ggcgggcgcg ccgtcggcgc cggtgacggt ggcggcgggc agccagccgg
     1501 tccacaggga cagcaccagc agcaggccga tggagaccac gaactcgggc agtgcgaagg
     1561 ccgcggtgga ggtgagatcc acgatgcggt ccaccgcgcc ccgggggcgt gcggcggccc
     1621 agatgcccag ggcgagggcg ccgagcacgg tcaggacgaa ggcggtgccg cccaggagca
     1681 gggtgttggg caggggagcg gcgagcaggt cggtgacgtg ctggccccgg gcggaggtgc
     1741 ccaggtcgcc ggtgggcagg gcggtgatcc agtcccggaa acgttcccac acgggccggt
     1801 ccaggcccag cagatggcgg cgggcggcga ggccggcggt gccctcaccg cgttcggagg
     1861 tggccgaggc cgcgtcgccg ggcagcagct cgatcgcggc gaacaccacg gcgagcagga
     1921 ccagcagcat cacgaggcgc ttggcgagta cggcggcgac gcgggccgcc agggtgcccg
     1981 cccggcgcgc ggccgaggcc gtcacgggcc gggcggcggc ctcggccgga ggcgcggtgg
     2041 tgtcggtcac cgggacagcc agacgttttc gagctggacg cgtccgtagc cggggagttg
     2101 gggcaggcgg tgcaccttgg gcgcggccag gtcgattccg tcggccatgc cccacaggag
     2161 gtagccggac cggtcgtgct cgatctgctg gaggtcgcgc agggcggcgg tgcgggcctc
     2221 gggggcgccg gtggcgatgg ccttgtggta ggcggcgtcg aagtccttgt ccgaccagcc
     2281 ggcttcgttc tgcccggatc cggtggtcat ggtcttggac gcgaagaaga ccacggagtc
     2341 gttggtgccc cagtagttgg tgtagaggtc gcccttgagc caggtcttgt cgtagaaggt
     2401 gccggactcc tgcttgacga cctcgacctt gacgccggcc tcgcgggcct gggcggcgaa
     2461 cagggtggcg gactccgcga gcccggcgat gtcctcggtg gtgaccagct ggtaggtctt
     2521 gccgaagtcg aacccggcct ccgtgagcag ctgtttggcc ttggcgaggt cgcgggtgcg
     2581 ctgcgggatg ttcttggcgt agccggggtc gccggtgccc aggatgtcgt tggcgacggt
     2641 gccgtatccg gacaggacct gcttgaccat ggcctcgcgg tccacgatca gcttcatcgc
     2701 ctcgcggacc ctggcatcgg cgaacgggcc gccggaggtg cgcatcacga ggggcatcgc
     2761 catatcgttc gggcgccgga tgacctggat gtccttgcgc gcgtcggcgg tgcgggccgc
     2821 gacggcgccg gcgttggagg ccaggtcgat ctgaccggac agcatcgcgt tcgccatggc
     2881 ctgggggctt tcgaacatgg tcacctcgat ggcgtcgagc gggaccgggc cgccgtgcca
     2941 gtgctcgttg cgcagcagcc gggcgttgcc gccgcggtac cagtcgagct tgaaggggcc
     3001 ggtgcccggg gccttggcga tgtccttgtc gggggtgtcc ttcttgagga tgaacgtcga
     3061 caggcgggtg atcatgggga gttcggcgtt ggcgaagtcg gagacgagga cgacggtgtc
     3121 cttgccgtcg gcggtgatgt ggtccgccgt gattccgggc aggcgggcgg ctccggcggg
     3181 ggtgttgcgc aggcggcgca gcgaccagac cacgtcctcg gcggtgaccg ggctcccgtc
     3241 gtggaacgtc gcccccttgg cgatggtgaa gcgccaggtc ttgaggtccg ccgagggctt
     3301 ccaggcggag gcgaggcggc cgacggtgtt ctgcttgaga ccgggtgcgg tgagggtgtc
     3361 gtagaccagg gcgatgacga ggtagtcgct ctcgttgccc tgattgccgt gcgggtcgcg
     3421 ggtgatggcg gaggcgcggc ccagggcgcc gacgcgcagg gtgccgccct tctgcggagt
     3481 gccgccggaa ccggaggacg ccgcgtcctt gccgcccccg caggcggcga gcagcgcggc
     3541 cgcgcccatg ccgccgccgg cccacagcac ctggcgcctg ttccagtcca cgtcgccctc
     3601 gctccactcg tccgcaaatt cttagggttg cctatcctaa tgacggctat tttcacaaga
     3661 gtgcggggtc ggccggtagt gcccggccgt catcggccgg cgctcggggg tggtgatcgg
     3721 cccctcgtgg gacgggagtt ccgggtggtg gaacgggaag ttccgcgggt gcgcacagaa
     3781 atgacgaaat ggttaggctt gccttgccta agtcgaatgg gtagcttcct cacgtccgcc
     3841 ggacgccggg cacggggacc gcgcgctgaa ccgtccccgc acaccggccg cagcgcgcgc
     3901 tccgccatgc ccgggagccg cgcgcggacc cgatccgccg ccctcgttcg ccgccctcaa
     3961 cggaaacgga ccgcctcgac atgagcacgg gaaccgcccc cgtccgccca ctcgacaccg
     4021 ccggcgccga agaactgcgc cgggccgccg agcagatcca caccgaattc ggcacctcgg
     4081 ccacctcacc cggactcctg gcccgcgtcg ccgagtccgc cgccggactg agcgaacccg
     4141 tccgccatca gctgcgcccc gtcgacaccg acgacggcct gttcgtcctg cggggcctcg
     4201 acgtcgacga cgacgagata ggccccaccc ccgccggctg ggccgccgcg ggcgacagcg
     4261 ccgccgtcca cgacatcgtc ctgctgctgc tcgccaccgt catgggcaac cccctcgcct
     4321 gggaagggca gcaggacggc cgcttcgtcc acaacatcgt gcccgccccc ggccacgaga
     4381 ccgaacagac cggcgccagc agcaccgtgc tgctcagccc gcacaccgag gacgccttcc
     4441 accccggccg cgcccatctg ctgatgctcg gctgcctgcg caaccacgac tccatcgcca
     4501 ccaccgccgc cggcatccgc aaggccgaac tcgacgaggc cgacatcgcg ctgctgagca
     4561 ggcccctgct gccgatcctc cccgacgacg cgtacaccgg ggcccgggac ttcgacgggg
     4621 gacacccgcc cgccgtcccc accctcttcc gcgccgagga cggcctgacg ctgcgtttcg
     4681 accccgccta caccccggtg gccgacgccc cgcccgccca ccgcgccgcc taccagcggc
     4741 tctccgacga actcgcccgc gtctcggtcg ccgtgagcct gcggccgggc gaggtgctga
     4801 tcgtcgacaa cgacctcgtc gtccacggcc gcgtcccgtt ccgggcccgc tacgacggca
     4861 ccgaccgctg gctcaagcgc gcctccgtcc gcgtccccgg gcggcgcacc cgcccgccgg
     4921 ccgaggccgc cgaacacggc tacggtcagg ccgccgtcga agcccacgcc gcctgaccac
     4981 ccaccacacc gaggacggac atgaccgaga cgaagaacca ggccgccgac gccgcccccg
     5041 gcatacccgc cgacgacacc accctgcgca tactgtccac cagcgacctc gccggtatcg
     5101 acatcaccct gaccgacgtc gtcgacacgg tggagggcgc ctaccgcacc ctggccgcgg
     5161 gccggtcgga caacccccgc aaactcaccg tgcggcccgc cgacggccac tccgtctcct
     5221 acgcgatgct cggccgggac ggttcccgca acgtcgtcgc cttcaagacc tcgtacaaaa
     5281 acggtctgga caagggccgc gcggaacagc actactacac cgccctcacc ctctacgacg
     5341 acgtcaccgg cctgccggtc gcgatgatgg actgcggccg catcggcgcg ctgcgcaccc
     5401 ccgccgtctc cgcgctgctg gcccgcgaat gcgcccggcc cggcgcccgc agcgccctgg
     5461 tcatcggcac cggcacccag gggcgcctgg ccctgccgtt cctgctgacc accctgccgg
     5521 acctgacgcg cctgatgctc tgcggcaccc accccgaggg catcgccgcc gtacgggagc
     5581 acctgcgcac ccacttcccc gaccgggacc tggagatcgt caccgacctg cgggccgcgg
     5641 cgggcgacgc cgacatcatc ctcgccaccg ccggcggcca caccaccgcc gcggtcgagg
     5701 ccgactggct caagcccggc gcgctcaccg tcctcgtcgg ccacgggctg gcgccctcca
     5761 ccctccaccg cgccgaccgc gtcgtggcca ccagcgaggc gcagatgaag gtcaccggca
     5821 ccgacatggc cgacgcgagc ggcggattcc cggccgtcga caccgagttc ccgccggtca
     5881 tcgcgggcgt caccgccggc cgccgctcgg cggaggaacg cgtcttcgcc tacaacagcg
     5941 ggctcgtcgt caccgatatc gccctcggcc accgcttcgc ccaactcgcc atcgaccagg
     6001 gcctggggca gcaggtgccg ctgtggcggt gaccggcccg cgcaccacgg acctcccggc
     6061 cctgccggcc caccccgacc ccgaaaccga ccaggtactg gacagcggcc tgctgcacga
     6121 gctgtcctac gccttcggcg gccccttcca cttcctgctg ccgcaccggt tcgacgccaa
     6181 cctcaccgcc ttccgcaccg cgctgcgcga cgccggtgtg gcgggacggg tgtactacgc
     6241 gaagaaggcc aacaaggccg ccgtatggct ggaacgctgc gccgccaacg acgcgggcgt
     6301 ggacgtcgcc agcgccccgg aactgcgcca ggccctcggg cacggcgtac gcggcgagca
     6361 cctcgtggtc accggccccg ccaagagcga ggaactgctg cgactggcca tccgccacgg
     6421 ctgcctgatc gcggtggacg ccctcgacga actcgacctg ctccgcgccc tcaccgggga
     6481 cggcgcggga cgccccgccc ggctgctgct ccgccggctc ccgcccgccc agccgcacag
     6541 ccgcttcggc atgcccgacg ccgagctgac ggcggccctg gagcggtgcg tacgcgccgg
     6601 ggacgcggta cgcatggagg gcttcagctt ccacctcgcc ggctacgcca cccggccgcg
     6661 cgccgacctc gccggcgaac tcctcgactg gtgcctgcgg gcgcgggccc tgggactccc
     6721 ggcggaccgg atcagcatcg gcggcggctt cgccgtcgac tacacctccg ccggccactg
     6781 gcagaccttc ctcgccggcc agcgccccga gcactaccac gcccgcaaga cgttccggaa
     6841 cgccgacttc tacccctacc actcaccggt cgccggagcc ggcgcgctgc gcgagatcct
     6901 ggccaccgtc cccgcgaacg ggcacaccac cttggccgcc cgcctccacg agaccggcac
     6961 ccggctgctg acggaaccgg gccgtgctct gctggacacg gcgggcgcgt ccgtcttccg
     7021 cgtccagggc gtcaaggacc gcgacggcta ccggatcgtc accgtcgacg gcaccagcct
     7081 gagcctgtcc gagcagtggt tcaacagcga atacctcccc gatccgcagc tggtgacccc
     7141 cgcgggccgg gcccacggcg acggcgtcca ccccgcctgt gtgggcggtg cctcgtgcct
     7201 ggactccgac ctgctcacct ggcgcaagat ccgcttcccc gcccgccccc gcgtcggaga
     7261 cctgctggtc tacccgaaca cggccggtta ccagatggac tccaacgagt cccccttcca
     7321 cgacctggcg ctgccgccca aggtcgtcct ggaccgcctc ggcgcccgcc cgcgctggcg
     7381 cctggaccgc cgccccgccc tctgacctcc cgccacctgc cccaggagcg cccccatgaa
     7441 cgaggccctc gcgcgccccg ccgtggtctt ccgcatatcc gaactcatcg gatacacccc
     7501 gctgttcgag ctctgccgca ccgagaccgg cagccgcctc ctgctcaaac tggagatgta
     7561 caaccccacc ggcaccgcca agatccggat ggcccgccag atggtcctcg acgccgaggc
     7621 gcgcggcgaa ctgcggcccg gcggccgcat catcgagtcc acctccggca acaccggcct
     7681 gggactggcg gtcatcgccg ccgaacgcgg ctacaccttc accgccgtcg tcgaccacca
     7741 cgcctgcgcc gacaaactgc gcgccatgcg ggcactgggc accgaactcg tctatgtcgc
     7801 cgaggacggc accgacgaac tggccaccgc cgcccgtgag gaactggccg aggacatggc
     7861 ccgcggccag gacaacacgg tcttcaccga gcagcacaac aacctcagca acggcatcgg
     7921 ttactttccg gtcgcccacg aactgcatca ggccctcgac gggcaactcg acgtcctcat
     7981 cggtgcggtg ggcaccggcg gcgcgctctg cggcaccgcc cgcgaactgc gcaccctgat
     8041 gtccggcgtc accgtgatcg gcgtcgagcc caagggctcc atcgcgttcg gcggccccgc
     8101 ccacgactac taccagtccg gcaccggcac ccccgaaggc gccgagatcg gcgcgctcgt
     8161 cgactacgac ctgatcgacg aaggcgtcaa ggtcggcgac atcgaggcat ttgccaccgc
     8221 ccgcgccgtc gcccgtaccg gcctcctcat cggcggctca gccggcggcg tcgtccacga
     8281 agccctcacc cggctgcccg ccctgccccc gggcaccact atggtcgccc tggtcaacga
     8341 cggcggcgaa aagtacctgg acaccgtctt cgacgacgac tggatgaacg cccgcaacct
     8401 cctcgccccc gccgtggaac gcgagatcga cgaaacgctc accaaactcc gcaggaactg
     8461 atgccgccat gcagctgacc atcctcctcc gcgacagccg tgccctggcc accctcgccg
     8521 tccccctcat cctcacccag ctcgcgcagg tggccctgac caccaccgac accgtcatga
     8581 tggggctgct cggcacggtc gacctcgcgg caggagggct ggccatcgtc atcttcaacc
     8641 agctgcgcac catgggcgtg gggctggtca cctccgtcgg caaccagatc gccgcggcct
     8701 ccgcacgggc ggaagcggca cagggctccg gggcgccgga cgccggcggg gcggagcgcg
     8761 acggagccga cgacccggcg gagggcagcg gcgccggtga cccggtggag agcagcggcg
     8821 ccggtggccc ggcggagagc ggtggcgccg gtgacccggt ggggagcggc ggcgccggtg
     8881 gcccggcgga gagcagtgag gaggtccgcc ggatcgtccg cgccagcctg gcggtggcca
     8941 ccctcgccgg ggtggccgga gccgtcctga tgctcctcat cggccaggcc ctcaccccgc
     9001 tcggccagga agccgacgtc gtcgaccgcg cacagacgat gctgctcgcg ctcgcgcccg
     9061 gcctggtgcc ctgcctgtgg ttccaggcca tccgccagtt caccgtcggc atgcgccgcc
     9121 cgcaggccct gctccagatc accctcgcct ccgtcgccgt caacgccgcc gtcaactggg
     9181 ccctcatcca cggcacctgg ggcctgccca aggtgggcct gcccggtgtc ggcgtggcca
     9241 cctcgctggt ctacctgctc tccttcctcg ccctgtacgc ctccgcgaag cgggatgagg
     9301 tcctcggccc gctgctcagc ctcaacatcg cggcggccga ccgcgccacg gtccgccgcc
     9361 tcgtcaagct cggcataccc atcgccgcga cctacggctc cgaggccggg ttcttctccg
     9421 tcaccgccct gatggccggg tccttcggca gcgccgccct ggccgcgcac accgccgtca
     9481 accagctcgt ctacatcgtc ttccaggtcg cggtcggcct ctcccacgcc gcgtcgatca
     9541 acgtcagccg cgaactcgcc ctcggccgca ccgacaccgc actgcgcatc aagaacaccg
     9601 cactggcctg cgccgccgcc gtcatggccg tcgtcgcggt cctctacatc accctgcccc
     9661 acctggtcct gaggcccttc ttcgacaccg gcggtgccaa ggacgccgaa gccgtcgcca
     9721 tcgccaccca tctgctcctc gtcatcgccg tcctccagtt cttcgactgc gcccagaaca
     9781 tcggcgtcgg cctgctgcgc ggcctcgacg acaccaagag cggattccgc atcaccctca
     9841 tcggctactg ggtcgtcggc ctgcccaccg cctggctcct cggctacgcc gccggcctcc
     9901 acaccctcgg catctggctc ggcctgctca ccggcctcgc cgtcaccgcc gccctcctcc
     9961 tgcgccgcta cggcaccagc cttcgggcta ggggcgccgg gcagggggtg gcggctgcgg
    10021 cgtagggggt tctgttggtg tggtgtggcg cgaggtgtga cgtggtgtgg tgcggcctgg
    10081 ctgggggctg gggcaggttg cgggggtggg gcgtgggcgg ggtgggggtc ggccgagggg
    10141 ggacggatac ggggcgccgt cgcttccgct gcggaggcca acgcggccac tgatgccgat
    10201 gccgacacga cgggcctccg ttgttgtccg gtctggctgg ggtttgttgt tgtgggtgct
    10261 ggccgtggcg ggcaacggat gcagtgtgct gccgtcgccg tcgccgaggt caagaccggc
    10321 accgggtcgt caccgatacc gctaccgagg ccaacatcgg caccgatacc gccaccaagg
    10381 tcatcacgga cactgacacc gatgcctaca ccacgggcct cgtgtcgttt ggtctggcca
    10441 gagcccgttg ctgcgggtgt tgaccgtggc gggcaacgga tgcggtgtgc tgccgtcgcc
    10501 gccgccgagg tcaagaccgc caccaggtcg tcaccgatac cgccgccgag gtcatcgcgg
    10561 acgttgatgc cgacgccgat atggcgggcc ccgttgtcgt ccggtttggc tggggcctgt
    10621 tgctgggggt gctggtcgtg gtgggtagcg gatgtggtgt gccgctgttg ctgccgccga
    10681 ggtcaagacc ggcaccgggt cgtcaccgac accgctaccg aggccaacac gccaccaagg
    10741 ccatcacggc cactgacgcc gacaccacgg gccccggtta ccgtccggtc gggccggacc
    10801 ccatgctcac cgccgctctg atgaccgtcc ccggagtgcg ccccgccccg atgccgactc
    10861 cgagcgcgat cgctatcaga tgaccggcgt cggtgaacgt ccgctccgaa cgcagcaccg
    10921 gccggatgcc cagcgccagc agcccggccg tcgcggcggt ccgcgcgcca cggtgcggga
    10981 cggtcatggc aagcgcgccg agcgtggcgt tcagcccgta gctcacgccg acatcgatcg
    11041 cccgcgccgt cgcgtcgggc ggatcggcgc ggacccggcc gcgcaggccc gcgtagacca
    11101 gcaggctggc cccgatatgg cccaccgcga acacgccggc cgcccgccgt gggccccatc
    11161 gcgcctcggc cgtgcccagg gcgacgagca gcgccgcgct gtacggcagc ggcaacggct
    11221 cctcgatgaa cgccgcgctg gtgaccagcg tccgccaccg gccggcccgc agattttcga
    11281 cgttggtgga gtgcgcgcgc agcaactccg cccgccgcgc accgggcagc cgcgcggcgg
    11341 cgtacgcgcc cacccctaca gcgacgacat acagcggcgc gacccagggc aaccggcgcc
    11401 acacggacga gcccgaggac acgagagggg acaggggcgt tggcgcaggc gtggactcgg
    11461 gcgcggccgg cgggttggac gggggctcgg acgtgggcgg gggcgcggcg gcggacgagg
    11521 ggctggacgc ggtcgggggc ttcgacgcgt acaggggctt gggcctggtc gaggacttcg
    11581 ttgtggccgg gaacttcggc acgaccgggg actcgggcgt ggatgaggac ttgggcgtgg
    11641 atgaggactt tggcgcggac gggggctttg gtgcggacga gaacagagac gggacccagg
    11701 gggaactcga cgcccaccgg gagccggaga cccatcgggg actggagacc catcggaaac
    11761 ctgaggcccc tcgggagtcc gaggcagtga gggaactcga ggccgggtga gagcccgacg
    11821 ccgggcggga gctcgacgcc caccgggagc cggagtccca tcgggcgccg gaggcccctc
    11881 gggaacccga ggcagtgggg gaacccggag ccgcgtggga acccgacgcc caccgggagc
    11941 cgaccgtgac cgaccgggag ccaggggccg gcgggggcac cgaggagacc catcgtgagg
    12001 ccgccgagac cgaccgggag ccgacggaga ccgaccggga gatcacggag accggccacg
    12061 agaccgcggc gaggacggag agccgtcccc agagggagtt gttcgccgac atctcagacc
    12121 ccctccggca gccgcttgcg ccagtccggc ccggcggctt cgacggcctg ctccggatcg
    12181 ccgacccacc gcacgggcgg gcccgccgct atccaccgtg ccccgtccgg cgagaccggg
    12241 cggtccccgg cggcacagac ggcaggcgcg cccgccacga acgggccttc gccgtcacgc
    12301 cggatccgcg tgagcgcctg gctctccccg aggccccgct cgggggccgc gaactggtcg
    12361 tcgtagccgc cgaaccgccc cagcaggctg gacggttcgc cgtcggccgg gcgcgggtgg
    12421 accggcccgg tatcggtctg cacggtgatc gcaagcatgg gtacagcgtg ccagccgcca
    12481 ctgacaacgg cccgacagga gtgccgcacg accccgaacc acagcgccgc ggacccaact
    12541 cccgtccatc cactgccctt cacccgacct cagctcacct tcacctttct tcccaacccc
    12601 aactcctgcc ccatacaccg ccgtcacgag acctcaacgc tccgaccacc ggccaccaca
    12661 gcccgcctgg cacggccatg cccctgccac agccctgtgc tgcccccagc ttgaactcat
    12721 cggacgcgag ctcctcaaga actcatcgga cgagcgttcc tcaagatgcg cgctcctcag
    12781 gcgcgcgctc cgcggtccgg cacgccgaga cccgcctccg cctcccggac ctgcacagcc
    12841 gcccagacca cacgccgggc ctcgtacctg cgccactcga cgccgcgccc cgcacccgcg
    12901 ccactcgacg ccgcgccgcc cggcactgca ccgcccgtac ccgcggcgcc cggcaccgcg
    12961 ggtagccgat caccggcccg ccgatacgcc ggcacccgga tacgccgcca cgcctataca
    13021 ccgaccccca gcaaccggaa tacccgactc cccctctcct ctccccgccg caccacgcgg
    13081 aacactgtcc ccatgacctc tacgcctccc atggcctcta cgtccccggt agcctctacg
    13141 tcccccgtgg taaccccgcg catcggactc ctcggcaccg gcccctgggc gcaaagcgtc
    13201 cacgcccccg cgctcgccgc ccaccccggt gtcgacctcg ccggtatctg ggggcgcagc
    13261 caggccgccg ccgcggaact ggcgcacacc cacggcaccc gcccgtacgc cacccctgac
    13321 gagctgttcg ccgcctgcga tgccatcgcc atcgccctgc cgccctccgt ccaggccccc
    13381 ttggcggtac gcgccgccga ggccggctgt caccttcttc tggacaagcc ggtcgccacc
    13441 accgtggccg aggcccgcgc c
//
