LOCUS       NZ_NDXL01000003        25002 bp    DNA     linear   CON 27-APR-2024
DEFINITION  Streptomyces kasugaensis strain BCRC 12349 scaffold3, whole genome
            shotgun sequence.
ACCESSION   NZ_NDXL01000003
VERSION     NZ_NDXL01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces kasugaensis
  ORGANISM  Streptomyces kasugaensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 2433044)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Comparative genome analysis for kasugamycin overproduction
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2433044)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Comparative genome analysis for kasugamycin overproduction
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 2433044)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030,
            China
REFERENCE   4  (bases 1 to 2433044)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. May-2015
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 188.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002261115.1-RS_2024_04_27
            Annotation Date                   :: 04/27/2024 02:42:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,951
            CDSs (total)                      :: 7,863
            Genes (coding)                    :: 7,657
            CDSs (with protein)               :: 7,657
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 206
            CDSs (without protein)            :: 206
            Pseudo Genes (ambiguous residues) :: 0 of 206
            Pseudo Genes (frameshifted)       :: 87 of 206
            Pseudo Genes (incomplete)         :: 170 of 206
            Pseudo Genes (internal stop)      :: 23 of 206
            Pseudo Genes (multiple problems)  :: 65 of 206
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:37:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1676559
            Orig. end                         :: 1701561
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NDXL01000003.1.
            Bacteria and source DNA available from BCRC.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25002
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="5"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25002
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25002
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15002](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15002
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(459..471)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.33"
                     /tool="antismash"
     gene            complement(468..1394)
                     /locus_tag="B7024_RS36375"
     CDS             complement(468..1394)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS36375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_094795167.1"
                     /transl_table=11
                     /translation="MIQHATEESAADLWAECPDEARQAAERVAGSPATWQLMDRGGRGT
                     ALWHVTGPGTQQIVVKVGHGQAAGVVAREITALACMQSAGVTATAAYGEDVQYGLARDT
                     AWLVRPWVKGLTTWDVFQAVRDERPDVGDYRRALVAAVDLCTAVGGLHQRGWVHGDLQP
                     HHSVHMATSRTVQLLGCTWAWSPDLPPSSAYTGGLVHFLSPELAAAAESPTRPVITSKA
                     GDVYALAASLWWAATGDWPVNYAAAAIDPNAHTAAVLRRMIAARRLKISTTSVWPQVTE
                     LLREVLTADAIQRPSAFQLAQRLRRLM"
     gene            complement(1560..2162)
                     /locus_tag="B7024_RS36380"
     CDS             complement(1560..2162)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS36380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_094795168.1"
                     /transl_table=11
                     /translation="MIQALDAFTVAAEYGRSHTTFRLYLEGQREPAARIHKDGAYDSRS
                     SFRVYAGAGLDELAGYVTEFAAMTAQRVKVGTVRHRERTWRPDNWTFTQHDLGVLSGLP
                     EGSGSRMRHSFPLRTVLDHFWGDALFSCRLRFRSPESEGFALVRLAGVRARYGITVHDP
                     RISRLLVLACIAQFNRYATTDPRKSAQEYLMPMPPQQ"
     gene            complement(2159..2368)
                     /locus_tag="B7024_RS36385"
     CDS             complement(2159..2368)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014181309.1"
                     /locus_tag="B7024_RS36385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5999 family protein"
                     /protein_id="WP_094795632.1"
                     /transl_table=11
                     /translation="MCQHRPPCPLADAPDREAAHTVARHSEQGWSLLCNGVLLFEDTGE
                     LLPNGQIIAPHRPLDEAPSVVSAP"
     gene            complement(2540..2719)
                     /locus_tag="B7024_RS40995"
     CDS             complement(2540..2719)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS40995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_143682261.1"
                     /transl_table=11
                     /translation="MVMTTAPPPRRPRRVRGALRYSLQALDRSGFGLGQVLVIGLFATT
                     VVGWLTIVFVSLSP"
     gene            complement(2713..3198)
                     /locus_tag="B7024_RS36390"
     CDS             complement(2713..3198)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS36390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_094795169.1"
                     /transl_table=11
                     /translation="MSVDQSPAFPDLLMASGGFYGDAPEPTMAAAGCAVVLYGCLAPGA
                     IHCAAQERRWLRATRVYAEQQGWVPVAEVVDRSRVSAHRATRDHWPAVVDLVARGKASG
                     IVTPSLVMLHSTAEERQALAGWQREMGVFVASPGSVQDVHHRLPSGFRYPAAVREAW"
     gene            3622..4461
                     /locus_tag="B7024_RS36395"
     CDS             3622..4461
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014174859.1"
                     /locus_tag="B7024_RS36395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_244934291.1"
                     /transl_table=11
                     /translation="MYLGKVLERMRNGRGYSIAEVATALGFSKEKLWRIERGRTSLPNP
                     KDLRALLEHYGEGDEETIEELSKINRESLRQGWWVPYNPHLQKGMRDYVGLEADARAIS
                     AWQPNLVFGLLQTREYALELLLSAKSIDETTTEFIDANVDLRMERKNLVTRDEPRQLWV
                     IMAEDALRSTIGSREVMSRQYEEIARLAALDHITVQILPAGSAGYRASQNFIMLNLEDP
                     LGTMVQADHVDGQVWVTDKKPDVGRFSRRFEALRAAALAPHETPSFLEALDTEDRAI"
     gene            4458..4679
                     /locus_tag="B7024_RS36400"
     CDS             4458..4679
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018560053.1"
                     /locus_tag="B7024_RS36400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_172451207.1"
                     /transl_table=11
                     /translation="MKSTDVAPEGAWYKSSYSGAEGNACVEIAKLTDEVAIRDSKDTAG
                     PALVVTRASWTAFVGLIGSSDAAHSPAN"
     gene            complement(5088..6230)
                     /locus_tag="B7024_RS36405"
     CDS             complement(5088..6230)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1229: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF033545.0"
                     /locus_tag="B7024_RS36405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS630 family transposase"
                     /protein_id="WP_244934292.1"
                     /transl_table=11
                     /translation="MIPFESPGVDWLVVPGMDLSSEQMDDLRELMSSRHVSADVALRAR
                     IVLWSAEGRRRKDIAELAGVVPVTVDRCKARYAARALAGLEEKRRGGPRDQVPPQTRGR
                     VIALTKMSPPAASGLSHWSTRALADHLKRREGISVSWHYVARIWREENLKPHRSGTFKV
                     SEDPAFADKVADVIGLYLAPPGGAVVLSIDEKTQIQALDRTQPVLPVTFAATEKRTHDY
                     IRHGTTNLFAALNVTTGEVLGECRPNRNAKNFLTFLKKAVTPHAGKDIHVVLDNLSTHT
                     TPEVKAWLSNNPHVHFHVTPVGSSWLNQVEIWFGILTRQSIRRGTFSSVNVLIKQIRDY
                     INSWNENAKPFTWTATAGEVLTKVRLVQTNMKKLVRNNSK"
     gene            complement(6639..6860)
                     /locus_tag="B7024_RS36410"
     CDS             complement(6639..6860)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018560053.1"
                     /locus_tag="B7024_RS36410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_172451207.1"
                     /transl_table=11
                     /translation="MKSTDVAPEGAWYKSSYSGAEGNACVEIAKLTDEVAIRDSKDTAG
                     PALVVTRASWTAFVGLIGSSDAAHSPAN"
     gene            complement(6857..7696)
                     /locus_tag="B7024_RS36415"
     CDS             complement(6857..7696)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014174859.1"
                     /locus_tag="B7024_RS36415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_244934291.1"
                     /transl_table=11
                     /translation="MYLGKVLERMRNGRGYSIAEVATALGFSKEKLWRIERGRTSLPNP
                     KDLRALLEHYGEGDEETIEELSKINRESLRQGWWVPYNPHLQKGMRDYVGLEADARAIS
                     AWQPNLVFGLLQTREYALELLLSAKSIDETTTEFIDANVDLRMERKNLVTRDEPRQLWV
                     IMAEDALRSTIGSREVMSRQYEEIARLAALDHITVQILPAGSAGYRASQNFIMLNLEDP
                     LGTMVQADHVDGQVWVTDKKPDVGRFSRRFEALRAAALAPHETPSFLEALDTEDRAI"
     misc_feature    8410..8425
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.02"
                     /tool="antismash"
     gene            8438..9643
                     /gene="fxlM"
                     /locus_tag="B7024_RS36420"
     CDS             8438..9643
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014138947.1"
                     /locus_tag="B7024_RS36420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_094795172.1"
                     /sec_met_domain="PCMT (E-value: 5e-42, bitscore: 140.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTANHSTVREPASLRAAMVSALRNEAAVTSESVAAAFAAVPRHR
                     FAPDAPLELAYDLHRTVPVKKDEQGLDISVMSAAHLQAVMLEQAGIEPGMNVLEIGSGG
                     YNAALIQELVGIDGAVTTVDIDRDIVDRARLCLDNAGYSQVKTVLADGEAGVPDGAPYD
                     RIIVTAAAWDIPPSWISELAKKGRLVVPLTSRGTTRSIAFDRDGRDLLSRSYCLARFVP
                     MQGDGAAEERKALLRDGVAVQTDDVRVRLDGQALNQALDTPRLERWSGAAYDLPDELEL
                     YLSLNLRLAARLHAAEHIVAQGLIEPSALYGVPALIGEDSIAYRTRRENNDTGGFESGV
                     IAHGPQAQALADEYVGLLRRWAQDHRRRGAATFRYRPGPAPSPLPQDAVLKRHGIVTAS
                     WH"
     misc_feature    complement(9726..9739)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.0"
                     /tool="antismash"
     gene            9729..9920
                     /locus_tag="B7024_RS36425"
     CDS             9729..9920
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009322874.1"
                     /locus_tag="B7024_RS36425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_094795173.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 1.2e-17, bitscore:
                     60.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVQLERPVAPAQPVTEDRQEPGQADFDLDITIVEGGPAADQLIR
                     LTSDGCNSTCATACVSCP"
     CDS_motif       9729..9851
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MTVQLERPVAPAQPVTEDRQEPGQADFDLDITIVEGGPAAD"
                     /locus_tag="B7024_RS36425_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9852..9920
                     /prepeptide="core"
                     /locus_tag="B7024_RS36425_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-1.70"
                     /molecular_weight="2135.4"
                     /monoisotopic_mass="2134.0"
                     /core_sequence="QLIRLTSDGCNSTCATACVSCP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTVQLERPVAPAQPVTEDRQEPGQADFDLDITIVEGGPAAD
                     "
                     /leader_location="[9728:9851](+)"
                     /alternative_weights="2153.5"
                     /alternative_weights="2171.5"
     gene            10001..12910
                     /locus_tag="B7024_RS36430"
     CDS             10001..12910
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123798.1"
                     /locus_tag="B7024_RS36430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_094795174.1"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 6e-19,
                     bitscore: 65.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_N (E-value: 8.6e-108,
                     bitscore: 358.0, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.4e-27, bitscore:
                     94.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYRYVDAAVVRAAAWSPDRQVTWPELTGPSANTASWRAWLQQIWQ
                     TADFATAVKVASPDLASRIDQVCAGHSLPDLAVRRTVLSVLRYLLRARTRATPFGLFAG
                     IAAARIGSAPALRVGAGHQATARPDAAWATALVDHFEEHSGLRPHLMLLASNLVIERDG
                     HVVIEHRPRGARDGAPEHVQIRVTGPVREALDRTRTPISWSDLTAKLSASFPTAPLAAI
                     ENLIAGLVKQRFLITNFRPAMTVIDPLAALLAHARHLAPAEAAALREAPKPALDLRVDW
                     DLVIPETVAKEAAAAAKALTRLAPRPALTGWTEWHSRFLERYGPRAVVPVVDAIEVLGY
                     PSGYLGSTTTPAPPIPLPDRDSRLIKLAHTAGMRRHLEVQLDDAALEELAATDPGHAVQ
                     PSTEVTVRIHAASVPAVKQGEFTLHVVGVARSAGATTGRFLGILDAEDRHRMTEVYAEL
                     PGVHQDALVAQISSTPLYIRAENVARAPQATELVISLGNYQSSDTSLVPVTDLAVTADA
                     ERLHLVSLSRRRPVHTLLLNAVDLDHHTHPLARFLIESPVALAVPCTGFMWGSAASNLP
                     FLPALRYGRTIVSAARWLLASDDLPGAPAPWPQWDQALAQWRRDVHLPERVYLSEADQC
                     MALDLAEPSHRALLRTHLDRDGKVTLRPAPEPRDLGWTGGRAHEVVIPLAASDQAVAPV
                     RGPGHVVGREHSHLPGCGNRIYLQLHGHRDRQNPLLIRHLPTLLEELGRARWWFVRYQN
                     PEDHLRIRLACAPGTLGSAIEQIGKWTQQLRHNGLITHASVETYHPETARFGGPTAMGA
                     AEEYFAADTTATLAQLAVQSGMNAPDVRALTAASMVDIVTGLLGNHAEAMRWLIEHTHT
                     DTSAPPRAVYRQAVDLVNADPSGLDAHVTAAWSARRVALAAYRSALEDAETQPQDLIAD
                     LLHLHHVRMCGPGLPQERAHLHLARAAALSWTARARRTP"
     aSDomain        10460..10726
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_B7024_RS36430_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="8.40E-21"
                     /identifier="RREFam001.1"
                     /label="B7024_RS36430"
                     /locus_tag="B7024_RS36430"
                     /protein_end="242"
                     /protein_start="153"
                     /score="65.5"
                     /tool="antismash"
                     /translation="ASNLVIERDGHVVIEHRPRGARDGAPEHVQIRVTGPVREALDRTR
                     TPISWSDLTAKLSASFPTAPLAAIENLIAGLVKQRFLITNFRPA"
     misc_feature    10799..10801
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12907..14151
                     /locus_tag="B7024_RS36435"
     CDS             12907..14151
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014138950.1"
                     /locus_tag="B7024_RS36435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_094795175.1"
                     /sec_met_domain="LANC_like (E-value: 6.8e-40, bitscore:
                     133.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTAPAAAALSTANQLAHTLADPRTVWPGGRPDGGRAWPQSLAG
                     GAAGIALLHIERARTGRGDWDTAHTWLATAVHGEVSAAANANLYFGAPALAFITHRAAS
                     ASSRYLRVLERLDEATLTVTRTRLTEALRRIDRAERPPMEEFDLIQGLSGLGAYHLSRH
                     PHHEITRDVLSYLARLTEPLHDPASLPPWWMNVAPTGAPSAGYPQGHGNFGLSHGIGSA
                     LSVLSLALLRDLAVPGIADAVERICAWTDQWRQGDETDIWWPGLISIQQATDGHVHPDL
                     RPRPSWCYGVSGTARAQQLAGLALHDPGRVQAAESAILATLRDPVQLDKLPETGLCHGM
                     AGLLHTAWRMATETDSTEIAAELPHLADRLITALDPDDLNPELLDGAAGAALALHTLGT
                     DSAPAPHWDTFLALA"
     gene            14172..15002
                     /locus_tag="B7024_RS36440"
     CDS             14172..15002
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009322883.1"
                     /locus_tag="B7024_RS36440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_094795176.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 9.6e-31, bitscore:
                     104.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPTWRQANVAFQNWERAEIVGLAQLAPLLSAAEDEGALTAWFL
                     VRKRPCWRLRYLPATEGHDRIGQGLDALITDGAISGWTQIVYEPEIHAFGGAEAMASAH
                     RLFHQDSRNLLNHLQGDAGNHRRETSLMLCSLLMRSAGQDWYEQGDVWARVGAHRALPT
                     DVEPDSRDRLHAAVHRLISVNGEDLMRAGGQLAHATDWAHAYTDAGRELAHLASSGQLH
                     RGLRDVLAHHVLFAWNRIGLPYVTQATLAAAAKTVIFGADPTAERTATDRVETP"
     misc_feature    14178..14180
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            15124..16116
                     /locus_tag="B7024_RS36445"
     CDS             15124..16116
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612040.1"
                     /locus_tag="B7024_RS36445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_244934294.1"
                     /transl_table=11
                     /translation="MASTVYNQAALIASDVGAPDTAREMCHQHAAAYLHAAPLPGRTAI
                     RALEPVVNLARLQLRAGQTDDGRQCLLALFNAVTTGSSAQVEDITVPADLVAYADDRQV
                     VRAWLWRVLLADGTRALTTAGRWAEALDHAKAHRGVGQRMLDGRQVAVLAALTSGNTRA
                     ANRLLVHTVPGEAWEDAVTNYLTILYHRISGRAWRRPLQNLATTYLERLDKDDMAVFDT
                     RLGLAVLDVVDSVNDPAARLVVAELHRRTMKTTDGYAAREILAHPLFTALATYQEAQDC
                     RALLRACALEAGTLPSELSDQLAAALRTSDRVIRGSVDHPERAHTSGRE"
     gene            16200..16478
                     /locus_tag="B7024_RS36450"
     CDS             16200..16478
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS36450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_244934295.1"
                     /transl_table=11
                     /translation="MAAIDGPNFGYVVVRRNPEKKNAEFGVHAFGPDGGAFAERLADIV
                     RTWGTEYRSTPGPRIAVYPAGTPDDRITGDRIIDKKRSRISVSWSAA"
     gene            complement(16959..17462)
                     /locus_tag="B7024_RS36465"
     CDS             complement(16959..17462)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010644469.1"
                     /locus_tag="B7024_RS36465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_094795634.1"
                     /transl_table=11
                     /translation="MTVNPLARFVPFPEPPALITEYIAERSAEESVVDGPSPWDIGALS
                     AELIAPLPEWLDAVCRWLNQTYAWQPQHVIPPCWTEHDHLTYEIAAFAFARADAYQEAG
                     SVVLWHEQYDRFLIRMNNALGKAGEECRIGRHDARPARFQLDAWPAKGSADAGVPEVAT
                     PSRS"
     gene            complement(17459..18793)
                     /locus_tag="B7024_RS36470"
     CDS             complement(17459..18793)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010644471.1"
                     /locus_tag="B7024_RS36470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_244934296.1"
                     /transl_table=11
                     /translation="MGSGKTLRFFAPLIRRWPGPVVATSTKPDLVELTLDARQHGDCPV
                     LAFDPQNIAPSLPRFRWSPINGAADTEIAMMRAKAFVAGSRIPGSAGQSSEGSAFYKGQ
                     AAKVLAAFLHAAALDGASIDWVLKWARKLTDPAPLGILNAHPGTGPGWADMLRTASTGD
                     SRTVGNTASTLDAALEPLMHQSVIEALRGNGEDPTDFREFLDAGGTLYLLGKDSEVNSV
                     APLTTAVTEDLLDIAEAHAITSPAGRLDPPLLGALDEAPNVAPIPSLRQRVADGRGRGI
                     TVIYGLQGWASARARFGEGTANELAAFTNNVVVFGGAKDPAFLKDMSDLCGQVERVRTT
                     KTTTSGERGGQSTATHTALEPVLRSDEIKGLAEGHALVLADNLPPVITRLDGMWTWDSW
                     PEIETQVRALRTANETVRAQQAAAKKSQADAHAAAWANRRTGAAV"
     gene            complement(18959..19207)
                     /locus_tag="B7024_RS36475"
     CDS             complement(18959..19207)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS36475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_094795179.1"
                     /transl_table=11
                     /translation="MDLLPNGLSVALYAVTAVCAIGLLIMWISSARARRNAGFTSKGQL
                     KRHLSAKAALRATEIRPSFTDDGKPDGPATPVELSKG"
     gene            complement(19207..19566)
                     /locus_tag="B7024_RS42980"
     CDS             complement(19207..19566)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040033.3"
                     /locus_tag="B7024_RS42980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6238 family protein"
                     /protein_id="WP_094795180.1"
                     /transl_table=11
                     /translation="MNGRKPLTLTALDRNLTHPTAAEQPHVRTVRDDIDSLHAEFLSAA
                     RNTARLAKQLDLNDSHAAGGHARAAVGHIWRAAEELHTAFHHAPPRGTGPFAPLSRLCA
                     RRMRYLAARAARNAS"
     misc_feature    19545..19560
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.43"
                     /tool="antismash"
     gene            complement(19618..21054)
                     /locus_tag="B7024_RS36485"
     CDS             complement(19618..21054)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007447302.1"
                     /locus_tag="B7024_RS36485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_094795181.1"
                     /transl_table=11
                     /translation="MTNLLDLAPLTPLHETVRRPLYTETTTSQALYLPIAPPTLGTAGA
                     VIGRELYSGKAFIYCPFFAFGDGLPGGNAIFMGDTGRGKSALAKTYTARQIRLGRKVVV
                     LDTKEQKEREEGEWAALGRSLTGHAPVKFAPGGGTTSSCINPMDPAIAGKRQIELLRTI
                     VELGLGKPLDEFAGSALRIAIRRAHQRAAEASRPPVLADVAGCLRAPDEADARAKQRTH
                     QELLSDGLEASYVLDRLCGSDQDSTGDLTGMLDGPTSLSIDLDADMVVFDLTKVPSGGV
                     AMTILVAVISVFLEEVWLRPMCECGTEPSHHERVTVDSSSGAWELGANPEADCRRYTQR
                     KRILVCEEAWHILGTPQLAGLLEKFLKFARGYGLSCLFIVHHLSDIDDSPETQAALKMA
                     DTVVVYSMKKSEAEDTARRLGLPAWTAEHIMRLRRGVALWKVGEVIYPGVQHLLTEAEQ
                     HLCFSSGSMADLATAPPETD"
     gene            complement(21051..22577)
                     /locus_tag="B7024_RS36490"
     CDS             complement(21051..22577)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010644475.1"
                     /locus_tag="B7024_RS36490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SCO6880 family protein"
                     /protein_id="WP_094795182.1"
                     /transl_table=11
                     /translation="MTARTYQFGKHRPTGLVGRRDLGEQAVLGCGAVAGLVCGYAFSAV
                     PVLAGLGLVTPLALALLVVYAPYRPKGTAQRRTLYRWWRIKRYHRQALQRTGGVWVSPA
                     IEAGVRPDGTAPDAALAEPEGIAGMTWLPVTVRGQKATVVLQPASRCVTATLEVASPGL
                     GGKEISEQEVALERWGGLLDAFGNTEEHPVKRIQVLARQLKSDPSAHQRFIAQRDESAA
                     TANAPQWLKDSYATLANAVSTSAEEHRYYITAHARFSRDFAADASARGAGDEGIAAAMG
                     SYMEELWERCEDADLSVIAPLDEGRLTAFIRNSYDPDHAIWDTHLPQAHAFPRNVDVRG
                     GEHVATRAAGSTSSWYHATAAVTSWPTTPVGPDFLSPLLIGMPDVIRTVAITQNLEPND
                     AAVERMLREDTNNQAEMHRNATRGRNVDPRDRIASDATSSRGMALASSGAAGAAVVGYI
                     SVSARSAEELARTKRTTASRARSAHLRIEWLDLEHARAFANTLPFAGGIK"
     gene            complement(22582..24204)
                     /locus_tag="B7024_RS36495"
     CDS             complement(22582..24204)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007447295.1"
                     /locus_tag="B7024_RS36495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_244934297.1"
                     /transl_table=11
                     /translation="MRLRLRDDAPGLLVVERTPSRGTLGRRLHTFVWVNVAVGFVFVPS
                     AVANPFCAIPFVCEAKAAIDFVSDPLGFLLQKLTEANIWFLRKMLELIQDSTKVDLTSP
                     GFLKQYAMIFAASSLFTAALWLVAVAKRAVRGVSLGTAASEAVGFLVLQFVVNAITPGA
                     IALLMRAIDEVTAVFEPYATANFTPFLANLLKILALNPRDGLGQLITVNLVMLAGALLM
                     WIELLIRGAAIYVGVALGPLVNAGLVDRDLWGKSKKWIGALLALGLSKPVLFALLGLGG
                     AILSDSTGSMSDAVSKILVGSLILLLAVFASATLYKWVPSFGDEMAQLHHDRKAASSSG
                     PAAAVDGPAQHVNRAMSTHIQDSLVGGGKSAGAKHSAQTTGGKAANSATVGGRQAGTAS
                     AKAAAGSGASGGAAAAGPVGVAAAAVKAGVNVAKNKAASSPGAQGPDAASSGGASTGQH
                     SSRAASSAPASARPQGTPSGSVVGPSSGTAAGPPATSPPPPRPAAPPASSGTTSGAGPS
                     TIPMPTKPSGPAASHKPATGKDQ"
     misc_feature    24281..24294
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    complement(24282..24295)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.0"
                     /tool="antismash"
ORIGIN
        1 gcggcgggcg gggatgacgg cgtccgatcg gtacgccggc cagcagccgt aagcagcggc
       61 gatctggagg gcctcacagg cgctcagagc gcggtacgtg tgcaccggca gcacgtaggt
      121 cccgtcctcc tgtccccacc gggacttgcc gcgcaagatg tcctggaccg ctcgctcggt
      181 gcgagcccgg taccactcgg catccccctc atggagcagt tcaccccggg tgacccacca
      241 gctcggccgg aagggcaccg cgtcgaatag cctgtccacc gtccggcccg gcagaagtac
      301 agtcgggatg gccaggcaga gcactatggc gaagccggcg gtcaggagca cgacgtggac
      361 cgggaaatac agcaacgtca gaacgtggag cgtcatcaga acgcgttgcg tgcggggcgg
      421 aaggggcgtc gtgagagagg gatcggcacc gggccgaggt ggcaccgtca catcagcctc
      481 cgcagtcgct gggctagctg gaaagcggac gggcgctgta tcgcgtccgc ggtgagcacc
      541 tcgcgcagca gctcggttac ctggggccag acgctcgtcg tgctgatctt cagccgccgg
      601 gcggcgatca tgcggcgcag taccgctgcg gtgtgtgcgt tggggtctat cgctgccgcc
      661 gcgtagttca caggccagtc accagtggcg gcccaccaca gtgaggccgc aagggcgtag
      721 acgtcacccg ccttggaggt gattaccggc cgggtgggag attcggccgc ggccgcgagt
      781 tcgggtgaca gaaagtgaac caggccgccg gtgtaggcgg aggacggggg caggtccgga
      841 gaccatgccc aggtgcagcc gagcagctgc accgtgcggc tggtggccat gtgcacgctg
      901 tggtgcggct ggaggtcccc gtgcacccat ccgcgctgat gcaggccgcc gaccgccgtg
      961 cacagatcca cggccgcgac caaagcccgt ctgtaatcgc cgacgtcggg gcgctcatcg
     1021 cgtacggcct ggaaaacgtc ccaggtggtc agccccttta cccagggccg caccagccac
     1081 gctgtgtctc tggccagtcc gtactggacg tcctcgccgt atgcggcggt tgccgtgacg
     1141 cccgcggact gcatgcacgc caacgccgtg atctcgcgcg ccaccacgcc agcggcctgg
     1201 ccgtgaccca ctttcaccac gatctgctgg gtgcccggcc ccgtcacgtg ccacagggcc
     1261 gtaccgcggc cgccccggtc catcagctgc caggtcgccg gcgaccccgc gacccgctca
     1321 gcggcctgcc gcgcctcgtc cgggcactcg gcccataggt ccgccgcact ctcttccgtt
     1381 gcgtgctgga tcatctcgtt ctccgttgtc gtatgcggtg gtggccccac gggcgaagtt
     1441 gccgtgctcg accgcgggcg cggtcggccg cctggctccg gcccgtggga cctgctgtgc
     1501 cccgccggcc gcccctcgtg ggcgcgcggg ctactcattg ccgttgccgg ccgaccgccc
     1561 tactgctggg gcggcatggg catcaggtac tcctgagcgg acttgcgtgg atcggtggtg
     1621 gcgtaccggt tgaactgcgc gatgcaggca aggacgagga gtcggctgat gcgtgggtcg
     1681 tgcaccgtga tgccgtagcg cgcccggacc ccggctaggc ggacgagggc gaagccctcc
     1741 gattcaggcg accggaaccg cagacggcag gagaagagcg cgtcgcccca gaagtgatcg
     1801 aggaccgtcc ggagcgggaa gctatggcgc attcggctgc cggagccctc cggcagcccg
     1861 gacaggacgc ccaggtcgtg ctgggtgaac gtccagttgt ccggccgcca ggtacgttcc
     1921 cggtggcgta cggttcccac cttgacccgc tgcgccgtca tggccgcgaa ctcggtgacg
     1981 tagccggcga gttcatcgag gccggcgccg gcgtagacgc ggaaggagga tcgcgaatcg
     2041 tacgcgccat ccttgtgtat acgcgccgcc ggctcccgct gtccctccag gtagaggcgg
     2101 aaggtcgtat gggaacggcc gtactcggcg gcgacggtga aggcatcgag agcctggatc
     2161 acggggctga caccacgctc ggcgcctcgt cgagcggccg gtgcggggca atgatctgcc
     2221 cgttcggcag cagctcacct gtgtcctcga agaggaggac gccgttgcac agcaggctcc
     2281 agccctgctc ggaatggcgc gccacggtgt gcgcggcctc ccgatcggga gcgtcggcga
     2341 gcgggcaggg aggccgatgc tgacacatca taggtgttcc tttcccaggg gccgactcgc
     2401 gcccgccgat ggcctcgtgg atacgaaggg ggccaggtgc tggtcgtctc ccggggcggt
     2461 ggggagggcc ccgggagacg accgtctgga ggccgccgga cgaccagctc atgggcaaag
     2521 ctggtggccc ggcggcggat cagggggaca gcgacacgaa cacgatcgtg agccagccga
     2581 cgaccgtggt ggcgaagagg ccgattacga gcacctgccc gagaccgaaa ccgctgcggt
     2641 cgagggcctg gagcgaataa cgcagcgccc cccgtactcg tcgaggccga cgtggaggcg
     2701 gcgccgtggt catcaccacg cctcccgcac cgcagccggg tagcggaagc cggagggcag
     2761 acggtggtgc acatcctgga cagacccggg cgaggcgaca aagacgccca tctcccgctg
     2821 ccagccagcc agcgcctggc gctcctcggc cgtgctgtgg agcatcacca gcgacggcgt
     2881 gacgatgccg gacgccttcc cgcgggcgac gaggtccact acggccggcc agtgatcgcg
     2941 cgttgcacga tgggccgaca cgcggctgcg gtccacgacc tccgcaaccg gcacccaccc
     3001 ctgctgctct gcataaaccc gcgtcgcccg cagccaccgc cgctcctgcg ccgcgcagtg
     3061 gatcgccccc ggcgcgagac agccgtacaa cacgaccgcg cagcctgcag cagccattgt
     3121 gggctccggg gcgtctccat agaaaccgcc gctggccatc aggagatccg ggaaggcggg
     3181 gctctggtca accgacatgg tccaacctgt cgcagtaggt agtacgagca cgagaatctc
     3241 agccggagcg ctacctcaat cggacagcac aggacatctc ccccgcactg atgcgaaccg
     3301 cgctgcgcag gcagcgctcc ggggccggat tcggctccgt cctctctttc cgagggcggt
     3361 gccttcgtcg gcacaactac ccttgcgcat gggaaagttg ccgtgcaacc cagcatgcaa
     3421 ttttcacgtg gattgtcata tgcaacaggc tggacttgtg gctgtgcaag gtgaactctg
     3481 ggtgtcagac tcagggctcg ggcacagtcg acatggactc cggggcggtc agacgggact
     3541 cgggcatacc tacgcccgac ttggggataa ctggggagga cttgcaaggt ggcagcaccc
     3601 aaaggaccta cgagccggcg tgtgtacctc ggcaaggtgc tggaacggat gcgcaacggc
     3661 cgcgggtact ccatcgcgga agtggcgaca gcactgggct tctccaagga aaagctgtgg
     3721 cggatcgaac ggggccgcac aagcctgccg aacccgaagg acctgcgcgc tctgctggag
     3781 cactacgggg agggggacga agagacgatt gaagagctca gcaagatcaa ccgcgagtcg
     3841 ctgaggcagg ggtggtgggt gccgtacaac ccccatctcc agaaaggcat gcgggactac
     3901 gtcggcttgg aggctgatgc ccgtgccatc agcgcatggc aacccaacct ggtcttcggg
     3961 ctcctccaga caagggagta cgccctcgaa ctgctgctca gcgccaagag catcgacgag
     4021 accacgaccg agttcatcga cgccaacgtc gacctgcgaa tggagcgcaa gaacctcgtc
     4081 acgcgggacg agccgcggca gctctgggtc atcatggcgg aggacgcgct gcgcagcacg
     4141 attggcagcc gggaggtaat gagccggcag tacgaagaga tcgcacggtt ggcggcactc
     4201 gaccacatca cggtgcagat actgccggcc ggctctgctg ggtaccgcgc gagccagaac
     4261 ttcatcatgt tgaacctcga agacccgctg ggaacgatgg tccaagccga tcacgtcgac
     4321 ggacaggtat gggtcaccga caaaaaacct gacgtcggtc gtttctcccg caggttcgaa
     4381 gccctgcggg ctgcggcgct cgcaccccac gagacgccga gtttcctgga agcactagat
     4441 acggaagaca gagccatatg aagtccacag acgtggcgcc tgagggcgcc tggtacaagt
     4501 cctcgtacag cggtgcagag ggcaacgcat gtgtcgagat cgcgaaactg actgatgagg
     4561 tcgctatccg cgactccaag gacacggcag gtccggccct ggtcgtgacg cgcgcctcat
     4621 ggacagcgtt cgtcggactc atcggttcca gcgacgctgc ccacagcccc gccaactgac
     4681 cgctcagcaa gtcgagtagg ccccctcaaa ggacctgagg gggcctactc atgcgtcttc
     4741 taccctcaca tggcgctacg acaaccccga catgccacta cggaccgtac gggccctgca
     4801 tctcccgaca tgcccctggg tgcgcccgca gttccggcac ttcgctcgcc atgccaggcg
     4861 ccctgccgcg ttgactcatc cttggcaacg cccccacttg ggatcgttat tttctgttgc
     4921 atgcggcaga tgcggcaatg tggagccgac gccgatgcgg ctgtatccag ttcaaaaaag
     4981 acttacctga aaggattaac cgcgccgggc gctttgccta aaaacgtata ggtgcatgtc
     5041 tgggtaaagc gcatgaattg gcctaatgtc tcgtgattcc gtttgtgtca ctttgagttg
     5101 ttcctgacca gcttcttcat gttggtctgg acgaggcgga ccttcgtgag gacctcgcca
     5161 gcggtcgcgg tccatgtgaa gggtttcgcg ttctcgttcc aggagttgat gtagtcgcga
     5221 atctgcttga tcaggacgtt gacgctggag aacgtgccgc ggcggatgga ctgccgggtg
     5281 aggattccga accagatctc gacctggttc agccatgagg agccgacggg ggtgacgtgg
     5341 aaatggacgt gcgggttgtt cgacagccac gccttcactt ccggtgtggt gtgcgtggag
     5401 aggttgtcca ggacgacgtg gatgtccttc ccggcgtgtg gtgtgacggc cttcttcagg
     5461 aaggtcagga agttctttgc gttccggttc ggcctgcact cgccgagcac ttcgccggtg
     5521 gtgacgttca gggcggcgaa caggttggtg gtgccgtgcc ggatgtagtc gtgggtgcgt
     5581 ttctcggtgg ccgcgaaggt gaccggcagg acgggctggg tccggtccag tgcctggatc
     5641 tgcgtcttct catcgatgga cagcaccacc gcgccgcccg gcggggccag gtagaggccg
     5701 atcacgtcgg ccaccttgtc cgcgaacgcc gggtcctccg aaaccttgaa tgtgccgctg
     5761 cggtgcggct tgaggttctc ctcgcgccag atcctcgcga cgtaatgcca ggacaccgag
     5821 atgccctcgc gccgcttcag gtgatcagcc aaggcccgcg tcgaccagtg cgacagcccc
     5881 gaagcggccg gcggcgacat cttcgtgagc gcgatcaccc gtccccgtgt ctgcggcggc
     5941 acctgatcgc gcggtcctcc acggcgtttc tcctccagac cagccagcgc gcgtgcggca
     6001 tagcgggcct tgcagcggtc caccgtcacc ggcaccactc cggcgagttc ggcaatgtcc
     6061 ttgcggcgcc gtccctccgc ggaccacaac acaatccggg cccgcaaggc cacatcagca
     6121 gacacgtgac gcgaactcat caactcccgc aaatcatcca tctgttcaga ggagagatcc
     6181 atgccaggaa caacgagcca gtcgacacca ggtgactcaa aaggaatcac gagacactag
     6241 atatcgaggc gagttgcgat tggtgagtcg atacggaaat ttccgagcaa agatctgaca
     6301 cggcgcttcg ctgaggagtg cggcgtagac ccccataagc tcttcgagct ctggcatcag
     6361 gaaaagaaag ccaaggcaac acctcaatag tccggcacca cccggacgat ggcggcctgt
     6421 cttcccggga gcgcggctga gtccaggtcg tcgccttcca ttcggagacc aggtccgagg
     6481 aacgttccac aaggtggccg cattcggagg gggaccggcg ctgacgcggt cgacgaggtg
     6541 cggcatgtcg gggttgtcgt agcgccatgt gagggtagaa gacgcatgag taggccccct
     6601 caggtccttt gagggggcct actcgacttg ctgagcggtc agttggcggg gctgtgggca
     6661 gcgtcgctgg aaccgatgag tccgacgaac gctgtccatg aggcgcgcgt cacgaccagg
     6721 gccggacctg ccgtgtcctt ggagtcgcgg atagcgacct catcagtcag tttcgcgatc
     6781 tcgacacatg cgttgccctc tgcaccgctg tacgaggact tgtaccaggc gccctcaggc
     6841 gccacgtctg tggacttcat atggctctgt cttccgtatc tagtgcttcc aggaaactcg
     6901 gcgtctcgtg gggtgcgagc gccgcagccc gcagggcttc gaacctgcgg gagaaacgac
     6961 cgacgtcagg ttttttgtcg gtgacccata cctgtccgtc gacgtgatcg gcttggacca
     7021 tcgttcccag cgggtcttcg aggttcaaca tgatgaagtt ctggctcgcg cggtacccag
     7081 cagagccggc cggcagtatc tgcaccgtga tgtggtcgag tgccgccaac cgtgcgatct
     7141 cttcgtactg ccggctcatt acctcccggc tgccaatcgt gctgcgcagc gcgtcctccg
     7201 ccatgatgac ccagagctgc cgcggctcgt cccgcgtgac gaggttcttg cgctccattc
     7261 gcaggtcgac gttggcgtcg atgaactcgg tcgtggtctc gtcgatgctc ttggcgctga
     7321 gcagcagttc gagggcgtac tcccttgtct ggaggagccc gaagaccagg ttgggttgcc
     7381 atgcgctgat ggcacgggca tcagcctcca agccgacgta gtcccgcatg cctttctgga
     7441 gatgggggtt gtacggcacc caccacccct gcctcagcga ctcgcggttg atcttgctga
     7501 gctcttcaat cgtctcttcg tccccctccc cgtagtgctc cagcagagcg cgcaggtcct
     7561 tcgggttcgg caggcttgtg cggccccgtt cgatccgcca cagcttttcc ttggagaagc
     7621 ccagtgctgt cgccacttcc gcgatggagt acccgcggcc gttgcgcatc cgttccagca
     7681 ccttgccgag gtacacacgc cggctcgtag gtcctttggg tgctgccacc ttgcaagtcc
     7741 tccccagtta tccccaagtc gggcgtaggt atgcccgagt cccgtctgac cgccccggag
     7801 tccatgtcga ctgtgcccga gccctgagtc tgacacccag agttcacctt gcacagccac
     7861 aagtccagcc tgttgcatat gacaatccac gtgaaaattg catgctgggt tgcacggcaa
     7921 ctttcccatg cgcaagggta gttgtgccga cgaaggcacc gccctcggaa agagaggacg
     7981 gagccgaatc cggccccgga gcgctgcctg cgcagcgcat ccaccaggcc gttccaccgc
     8041 tctactcgct atctcgctgt acgggctcga ttgtgcacct gcccacgccc cggccgcgct
     8101 cccctggggg aggcagtagc cgacccgctc aactgcccgc ccgtcgtcgg cgacgggcgg
     8161 gcgcgccacc cgatagccaa acctgaaaca agattcggtt gcctgaagaa acctgtggag
     8221 gggaggccct cccgccggtt tctacccaca aacgaactgc ccgagcggga ggaggaatag
     8281 cagtgacgag ccacggaact gcttttcagc cgaactctga gggctgccac tcctggcggc
     8341 gcgtatccgc gcccaaggca cggcgacctg gctagcgtcg cagccgacca ccaggccaag
     8401 gcgcccagaa cctacaatgg gaaacgatgg taacggcatg acaactgcta accattcaac
     8461 tgttcgtgaa cccgcctcac tgcgcgcggc tatggtcagc gcactgcgta atgaggccgc
     8521 ggtcacgtcc gagtcggtcg ccgctgcctt cgccgcagta ccccggcacc ggttcgcacc
     8581 ggacgcgccc ctagagctcg cctacgacct ccaccgcacc gtgccggtca agaaggacga
     8641 gcagggcctc gacatcagcg tcatgtcggc cgcccacctc caggccgtga tgctggaaca
     8701 agccggcatc gagcctggca tgaacgttct ggagatcggc tcaggcggct acaacgccgc
     8761 gctcatccag gaactcgtgg gcattgacgg agcggtcact acggtcgaca ttgaccgcga
     8821 catcgtcgac cgcgcccgtc tgtgcctgga caacgccggg tacagccagg tgaagaccgt
     8881 actcgccgac ggcgaggcag gcgttcccga cggcgcgccg tacgaccgga tcatcgtcac
     8941 cgcggccgcg tgggacatcc ctccgtcgtg gatcagcgag ctcgccaaga agggcaggct
     9001 cgtcgtacca ctgacgtccc gcggcacaac ccgctcgatc gcattcgacc gcgacggcag
     9061 ggacctgctc agccgctcct actgcctggc acgcttcgtg cccatgcagg gcgacggtgc
     9121 cgccgaggag cgcaaggcgc tgctgcgtga tggcgtcgct gtgcagactg acgacgtacg
     9181 ggtgcgactc gatggccagg cgctgaatca ggctctggac accccgaggc tggagcgctg
     9241 gtccggggcc gcctacgacc taccggacga gttggagctg tacctctcgc tcaacctgcg
     9301 gctcgcggcc cggctgcatg cggctgagca catcgtcgcg cagggactca ttgagccctc
     9361 ggctctgtac ggcgtgcccg ccctgatcgg cgaggacagc atcgcctatc gcacccgccg
     9421 cgagaacaat gacaccggcg gattcgagag cggcgtgatc gcccacggcc cgcaggccca
     9481 agcactcgcc gacgaatacg tgggcctgct ccgccgctgg gcccaggatc accgccgccg
     9541 gggagccgcg acgttccggt accggccggg ccccgcccca tcccccctcc cccaggacgc
     9601 ggtgctgaag cgccacggca tcgtcacggc ctcctggcac taagacgccg ggacccggcc
     9661 acgaccatcg cgtcaccgcc ggattccggg accttgcacc atcagcccac tgccccatgg
     9721 aggcatgcat gaccgttcaa ctggagcgcc cggttgctcc cgcgcagccg gtcaccgaag
     9781 accggcagga gcccggtcag gctgacttcg acctggacat caccatcgtt gaaggcggcc
     9841 ccgccgcgga ccagctcatc cgcctgacca gcgacggctg caactcgacg tgcgcgaccg
     9901 cgtgcgtgag ctgcccgtag cggcaccaga ggcgtctatt gcggtgcccg gccacgcccc
     9961 atgggcgcgg ccgggcaccg cgcggccaca ggaggggtgt gtgtatcgct acgttgatgc
    10021 agcagtggtg cgggcggccg cgtggagccc ggaccgtcag gtgacctggc cggagctgac
    10081 tggcccatcc gcgaacacag cgtcgtggcg cgcgtggctg caacagatct ggcagacggc
    10141 cgacttcgcg accgccgtca aggtcgccag cccggacctc gcgagtcgca tagaccaggt
    10201 ctgtgcaggc cattcgctac cggacctcgc cgtacgccgg acagtgctct ccgtactgcg
    10261 ctacctactg cgcgcacgaa cgcgtgccac cccgttcggc ctgttcgccg ggatcgcggc
    10321 cgcgcgaata ggatccgccc ccgcgctgcg agtaggcgcc gggcaccaag caaccgccag
    10381 gcccgacgca gcatgggcca cggccctcgt cgaccacttc gaggagcaca gcggactgcg
    10441 gccccatctg atgctgctcg cctccaacct cgtcatcgag cgcgacgggc acgtggtgat
    10501 cgagcaccgc ccacgcggtg cgcgcgacgg cgctcccgaa cacgtgcaga tacgcgtgac
    10561 cggaccggtc cgcgaggccc tggaccgcac gcggactccg atctcgtgga gcgacctcac
    10621 cgcaaagctc tccgcgagtt tcccgaccgc accgctcgcc gcgattgaga acctgatcgc
    10681 gggcttggtc aagcaacgtt tcctgatcac caacttccgc ccagcgatga cggtcattga
    10741 cccgctcgct gccctcctcg cacacgcgcg gcatctcgcg cccgctgagg cagcagcgtt
    10801 acgcgaggct cccaagcccg ctctcgacct gcgggtggac tgggatctgg tcatcccgga
    10861 gacggtggcg aaggaggcgg cagcggcagc caaggcactc acccgcctcg cgccccgtcc
    10921 agcgctgacc ggatggaccg agtggcacag ccggttcctt gagcggtacg ggcccagggc
    10981 ggtcgtaccc gtcgtggacg ccatcgaggt gctcgggtac ccatccggct atctcgggtc
    11041 caccaccacg ccagcaccgc ccatcccgct acccgaccgc gacagtcgac ttatcaagct
    11101 cgcccacacc gccgggatgc ggcgccacct cgaagtccag ctcgacgatg ccgcgcttga
    11161 ggaactggct gctacagatc ctggccacgc agtgcagccg agcaccgagg tgaccgtccg
    11221 catccacgcc gcgagcgttc cggccgtcaa gcagggcgag ttcactcttc atgtcgtcgg
    11281 ggtggcacgc tcggccggag cgactaccgg ccgcttcctg ggcattctgg atgccgagga
    11341 ccgccatcgc atgaccgagg tgtacgccga actacccggc gtacaccaag acgcgcttgt
    11401 cgcacagatc agctccaccc cgctgtacat acgcgccgag aacgtcgcgc gcgccccgca
    11461 ggcgacagag ctggtgatct cactcggcaa ctaccagagt tcagacacga gcctggttcc
    11521 tgtgacagat ctggcagtga ccgccgacgc cgaacggctg cacctcgtct cgctctcccg
    11581 acgccgcccg gtgcacacac tgctgctgaa cgcggtggat ctggaccatc acacgcatcc
    11641 gctggcacgg ttcctgatcg agtccccagt cgcgctagcc gtcccgtgca ccgggtttat
    11701 gtggggcagc gccgcctcca acctgccgtt cctccccgcg ctgcgctacg ggcggacgat
    11761 cgtgtctgcg gcccgctggc tcctcgccag cgacgacctg cccggtgcgc cggcaccgtg
    11821 gccgcagtgg gaccaggccc tggcccaatg gcgccgtgac gttcatctgc ccgagcgggt
    11881 gtacctgagc gaggccgacc agtgcatggc cctggacctg gcggagccct cacaccgggc
    11941 cctgctacgc acccacctgg accgcgacgg caaggtgacg ctgcgcccgg caccggaacc
    12001 cagggacctg ggatggaccg gcggccgcgc tcatgaggtc gtcatccccc tggccgcctc
    12061 cgatcaagcc gtcgcccccg tccggggacc aggccacgtc gtcggccgag agcacagcca
    12121 cctgcccggc tgcggcaacc gcatctacct ccagctccac gggcaccgcg accgacagaa
    12181 cccgctcctg atccgacacc tgcccactct gctcgaagaa ctgggccgag ctcgatggtg
    12241 gttcgttcgc taccagaacc ctgaggacca cctccgcatc cgactggcct gcgcacccgg
    12301 cacactcggc tccgccatcg agcagatcgg caaatggacg cagcagcttc ggcacaacgg
    12361 cctgatcacc cacgccagcg tggagaccta ccacccggaa accgcgcgct tcggcggccc
    12421 cacggccatg ggcgcagccg aggagtattt cgccgccgac accaccgcca ccctggccca
    12481 actcgccgtc cagtcaggga tgaacgcacc cgacgtccgc gcgctgaccg ccgcgagcat
    12541 ggtggacatc gtcaccggtc tgctcggcaa ccacgccgaa gcgatgcgct ggctgatcga
    12601 acacacccac acggacacgt ccgcgccgcc ccgcgccgtc taccgccagg ccgtcgacct
    12661 ggtgaacgcc gacccttcgg gtctggacgc gcacgtcacc gcggcatggt ccgcgcgccg
    12721 cgtggcactg gccgcctacc gcagtgcgct ggaggacgcg gagacccagc cccaggacct
    12781 gattgcggac ctgctgcatc tccaccacgt ccggatgtgc gggccgggac tgccccaaga
    12841 acgcgcccac ctgcacctgg ccagagccgc cgccctgagc tggacggcac gagcaaggag
    12901 gacaccgtga ccacgacagc ccccgccgct gccgctctgt cgaccgccaa ccaactggcc
    12961 cacaccctgg ccgacccccg caccgtttgg cccggcggcc ggccggacgg cggccgcgcc
    13021 tggccacagt cgctcgccgg aggcgccgcg ggcatcgccc tgctgcacat cgagcgtgcc
    13081 cggaccggcc gcggcgactg ggacaccgcg cacacctggc tggccacggc cgtgcacggc
    13141 gaagtaagcg cagcggccaa cgcgaacttg tacttcggtg ccccggccct cgcgttcatc
    13201 acgcaccgcg cagccagcgc atcgagccgg tacctacgcg tcctggagcg cttggacgag
    13261 gcgaccctca ccgtcacccg gacccgcctg accgaggctc tccggcgtat cgaccgcgcc
    13321 gagcgtcccc ccatggaaga gttcgatctg atccagggct tgtccgggct gggcgcctac
    13381 cacctgagcc gacacccgca ccacgagatc acccgtgacg tcctgtccta cctggcgcgc
    13441 ctgaccgagc ccctacacga tccggccagt ctgccgccgt ggtggatgaa cgtcgcaccc
    13501 accggtgcgc ccagcgccgg ctacccccaa ggccacggta acttcgggct ctcccacggc
    13561 atcggctccg ccctgtccgt gctgtccctc gctctgctgc gcgacctggc cgtacccggt
    13621 atagccgacg cggtcgaacg gatctgcgcc tggaccgacc aatggcgcca aggcgacgag
    13681 accgacatct ggtggccggg cctgatctcg atacaacagg caaccgacgg acacgtccac
    13741 cccgaccttc ggcctcggcc ctcctggtgc tacggcgtca gtggcacggc acgcgcccag
    13801 cagttggccg gactcgccct ccacgacccg gggcgcgttc aggcagccga aagcgcgatc
    13861 ctcgcgaccc tgcgcgaccc cgttcaactg gacaagctcc ccgagaccgg gctgtgccac
    13921 ggcatggccg gactactgca caccgcgtgg cgaatggcca ccgagacgga cagcaccgag
    13981 atcgctgcgg agctgccaca cctggccgac cgcctgatca ccgcgctcga cccggacgac
    14041 ctcaaccccg aactcctcga cggggcagcc ggagcagccc tcgccctgca caccctcggc
    14101 acggacagcg cacccgcacc gcactgggac accttcctcg ccctggcgtg accacccctg
    14161 gagaccgcct catgaagtta cccacttggc gccaggccaa cgtcgcgttc cagaactggg
    14221 aacgcgccga gatcgtcggc ctcgcccaac tcgccccgct cctgagcgcc gcagaggacg
    14281 aaggcgcgct caccgcgtgg ttcctcgtcc gtaaacgtcc gtgctggcgc ctgcgctacc
    14341 tgcctgccac cgaagggcat gaccgcatcg gccagggcct ggacgcgctg atcaccgacg
    14401 gggccatcag cgggtggacg cagatcgtct acgaacccga gatccacgcc ttcggcggag
    14461 ccgaagccat ggcatccgct caccgtctct tccaccaaga cagccgcaac ctgctgaacc
    14521 acctccaggg cgacgccggc aaccaccggc gcgagacctc cctcatgctg tgcagcctcc
    14581 tgatgcgctc cgccggacaa gactggtacg agcagggtga cgtctgggca cgcgtcggtg
    14641 cccaccgcgc attgcccacc gacgtcgagc cggacagccg cgaccgactg catgccgccg
    14701 tgcaccggct gatctccgtg aacggagaag acctgatgcg cgcgggtgga caactggccc
    14761 acgccaccga ctgggcacac gcctataccg atgccgggcg ggaactagct cacctcgcat
    14821 cttccggaca gcttcatcgc ggcctgcgtg acgtcctagc ccatcacgtg ctcttcgcct
    14881 ggaaccggat cggcctgccc tacgtcacgc aggccaccct cgcggccgcc gccaaaaccg
    14941 tcatcttcgg cgccgacccc accgccgaaa ggaccgctac ggaccgtgtg gaaaccccct
    15001 gacgccatag cccagcgctt cccgctcatc gctcgccccc gacctgcctg cctccctctg
    15061 ccccagcggg tgcgcacact cgtcgagctc gccgacaccg cagcgaccgt aagcgacccg
    15121 agtatggcct ctacggtcta caaccaggcc gcgctgatcg cctccgacgt cggcgcccca
    15181 gacaccgccc gcgagatgtg ccaccagcac gccgctgcct acctgcacgc cgcccccctg
    15241 cccggcagga cggcgatccg agcgctcgaa cccgtcgtca accttgcgcg gctccaactt
    15301 cgcgccggac agaccgacga cggtcggcaa tgcctcctgg cactgttcaa cgccgtcacc
    15361 acaggaagtt ccgcccaggt cgaggacatc accgtgcccg ctgacctcgt tgcctacgcc
    15421 gacgaccgcc aagtggttcg cgcctggctg tggagggtcc tcctcgccga cggcacacgc
    15481 gccctgacca ctgccggccg ctgggccgaa gcactcgacc acgccaaggc acatcgcggg
    15541 gtcgggcagc gcatgctcga cggccggcaa gtcgccgtcc tcgccgccct cacgagcgga
    15601 aacacccgcg ccgccaaccg tctcctggtc cacacagtgc ccggagaggc atgggaagac
    15661 gccgtcacga actacctaac tatcctgtac caccgcatat cgggacgggc ctggcggcgc
    15721 cccctacaga acctggcgac cacctacctc gaacgcctgg acaaggacga catggccgtc
    15781 ttcgacacaa ggctcgggct cgcagtactg gacgtggtcg actcggtcaa tgacccggcc
    15841 gcgcgcctgg tggttgctga gctgcaccgc cggaccatga agacgaccga cggctacgcc
    15901 gcccgagaga tcctggcgca cccgctgttc actgctctcg ccacctacca ggaggcgcag
    15961 gactgccgtg ctctgctccg cgcctgcgca ctcgaagccg ggacgctccc cagtgagctg
    16021 agcgaccagc tcgcggccgc actgcgcacg agcgaccgcg tcattcgcgg gagcgtcgac
    16081 catccggagc gggcccacac aagtgggcga gaatgatcta ggccaacggt aggtgtaaca
    16141 gatcaccgtt ccccgaactg gccaccggcg cgatcggccc caccaacctc gggttctcga
    16201 tggccgcgat cgacggcccg aacttcggct acgtcgtggt gcgccgcaac ccggagaaga
    16261 agaatgccga attcggtgtc cacgccttcg gacccgacgg gggcgccttc gccgagcggc
    16321 tggccgacat cgtccgcacc tggggcacgg aataccgcag cactcccggc ccacgcatcg
    16381 ccgtctaccc ggcgggcacg cccgatgacc ggatcaccgg cgaccggatc atcgacaaga
    16441 agcgcagccg gatctcggtc tcctggtcgg ctgcgtagca cgcggcgctt ggccaggttg
    16501 tcctgcacgc catcccaaca agtagggaac gtgatcgtat gaccactgcc gtactcgacg
    16561 gcgtcaccgc cttggtcgag ccgccagtcg gggatctctc cgacgacgat ttccagctgg
    16621 acgcccacgt cgtcgtctcc gagagcgctg tttaccactt caactgcccc accagcgacg
    16681 gctgtggcgc gcgccgtgca ggatgccctg gagccggccc cgccgcgcct ccgtatgtcc
    16741 cgcgtgcggc tggttctggc ggcgaccgac ctggcgccgg caggctgcga agcccagaga
    16801 cggcccctgc gcgacgcgat cgtcagcgac accacgcagg caggagacgc gtacgcagca
    16861 cgcgagatcc tgcgccagcc cttcctaccg gccggcgagc gggcacaccg tgatgagggt
    16921 cggaggcgaa gacgacgact gggtgcgggc tcatcagatc aactcctcga tggggtggcg
    16981 acttccggaa caccagcatc cgcagagcct tttgccggcc aggcgtccag ttggaagcgt
    17041 gccggtcggg cgtcgtggcg gccgatgcgg cattcttctc cggccttgcc gagagcgttg
    17101 ttcatgcgga tcaggaagcg gtcgtactgt tcgtgccaga gcaccactga gcccgcttcc
    17161 tggtaggcgt cggcgcgggc aaaggcgaag gccgctattt cgtaggtgag atggtcgtgc
    17221 tcggtccagc acggcgggat gacgtgttgg ggctgccagg cgtaggtctg attgagccag
    17281 cggcacacag cgtcgagcca ttctggcaac ggcgcgatca gctcggccga cagggcgccg
    17341 atgtcccatg gtgacgggcc gtccactacc gactcctccg cactcctttc cgcgatgtac
    17401 tcggtgatca gcgcgggcgg ctcagggaag ggcacgaatc gagccaaagg gttcacggtc
    17461 atacggcagc cccggtccgg cggttcgccc atgcggcggc gtgcgcgtcc gcctggcttt
    17521 tcttcgcagc ggcctgctga gcgcgcactg tctcgttcgc tgtgcggagt gcgcggacct
    17581 gggtttcgat ctcgggccag gagtcccagg tccacatgcc gtcgagacgg gtgatgacgg
    17641 ggggcagatt gtccgcgagg accagtgcgt ggccttcggc aaggcccttg atctcgtcgc
    17701 tgcgaaggac tggttccagt gccgtgtgcg tcgcggttga ctgccctcca cgttcgccgc
    17761 tggtggtggt cttggtggtg cggacacgtt cgacctggcc gcacaggtcg gacatgtcct
    17821 tcaagaacgc ggggtctttc gccccgccga atacaacaac gttgttggtg aaggcggcca
    17881 gttcgttggc tgtgccctcg ccgaagcggg cgcgggctga tgcccatccc tggaggccgt
    17941 agatcacggt gatgccgcgt ccgcggccgt cggcgacgcg ctgtcgcagg gaggggatgg
    18001 gggccacgtt tggtgcttcg tccagggcgc cgaggagggg tgggtcgagg cgcccggcgg
    18061 gggaggtgat ggcgtgtgcc tccgcgatgt ccaacaggtc ctccgtcacc gccgtggtca
    18121 gcggagcgac ggagttcacc tctgaatcct tccccagaag gtagagagtg ccgcctgcgt
    18181 cgaggaactc gcggaagtcc gtcgggtctt ctccgtttcc acggagggct tcgatcaccg
    18241 actggtgcat gaggggttcg agcgccgcgt cgagggtcga ggctgtgttg cccacggtcc
    18301 ggctgtcgcc ggtactcgcc gtgcggagca tgtctgccca tccggggccg gtgccagggt
    18361 gggcgttcag gatgccgagc ggggcagggt cagtcagctt ccgggcccac ttcagcaccc
    18421 agtcgatgct ggctccgtcg agggcagccg cgtgaaggaa ggctgcgagg accttggcgg
    18481 cctgcccttt gtagaaggcg ctgccctcgc tggactggcc cgccgagccg gggatgcgag
    18541 agccggcgac gaatgccttg gcccgcatca tggcgatctc ggtgtccgct gctccgttga
    18601 tcggtgacca ccggaatctt ggcagtgagg gggcgatgtt ctgcgggtcg aatgccagga
    18661 ccgggcagtc accgtgttgt cgtgcgtcga gggtgagttc cacgaggtcc ggcttggtgg
    18721 aggtggcgac gaccggcccc ggccaccgcc ggatgagggg ggcgaagaac cgcagcgttt
    18781 ttccgctgcc catggggccg atcaccctgc atgccttatc ggctcgtgac cacaggtcga
    18841 cgcccttagg gcggctggag gtgcccaggg cataaccaaa ttcgtaagga gaatggcgca
    18901 tggtgatatt cctagggaga gcgggaattg gtgactggag agggagtttc aaggccgatc
    18961 agcccttgga cagctccacg ggagttgcgg ggccgtcggg cttgccatcg tcggtaaatg
    19021 acggtcgtat ctccgtggcc ctgagggctg ccttggcgga cagatggcgc ttgagctggc
    19081 ctttcgatgt gaatccagca ttgcggcggg ctcgcgctga tgagatccac atgatcagca
    19141 gcccgatggc gcagacggcg gtgacggcgt agagggccac ggagagcccg tttggcagga
    19201 gatccatcag gacgcattcc tcgcggcgcg cgcggcgagg taacgcattc tgcgagcgca
    19261 gaggcgggag agcggtgcga aaggccccgt gccgcgcgga ggtgcgtggt gaaaggctgt
    19321 gtgaagctct tccgccgcgc gccagatgtg ccccacagcg gcccgtgcgt ggccgccggc
    19381 cgcgtgggag tcgttgaggt cgagttgctt ggcaaggcgg gcagtgttgc gggcagcgct
    19441 gaggaattca gcgtgcaggg aatcgatgtc gtcccgaaca gtccgcacgt ggggctgttc
    19501 tgctgccgtc ggatgggtca gattgcggtc tagggcagtg agtgtcaacg gttttctccc
    19561 attcatgcag agagcggcct tggggtccgg ctgaggaacg tgtggtgctg tcggctttca
    19621 gtccgtttcc gggggtgcag ttgccagatc tgccatcgat ccggaggaga agcacagatg
    19681 ctgttcggct tctgtcagga gatgctggac acccggataa atgacctctc ctaccttcca
    19741 cagggcgacg cccctgcgga ggcgcatgat gtgctcggct gtccaggcag gaagccccag
    19801 ccttctcgcc gtatcttctg cttcggattt cttcatgctg tacacgacga cggtgtctgc
    19861 catcttcagt gcggcttgtg tctccgggct gtcgtcaatg tcggaaaggt gatggacgat
    19921 gaagagacac gacaggccgt accctctggc gaatttgagg aatttctcca ggaggccggc
    19981 gagctggggg gttccgagga tgtgccaggc ttcctcgcac accaggatgc gtttgcgctg
    20041 ggtgtagcga cggcagtcgg cctccgggtt ggcgccgagc tcccaggcac cggatgagga
    20101 atcgacggtt acccgctcgt ggtggctggg ctcggtgccg cactcgcaca tgggccgcag
    20161 ccagacttcc tccaggaaca ccgaaatgac cgcgacgagg atggtcatgg cgacgccgcc
    20221 ggaggggact ttggtgaggt cgaagaccac catgtccgcg tccaggtcga tggacaggct
    20281 ggtgggcccg tccagcatgc cggtcaggtc gccggtcgag tcctggtcac tgccgcacag
    20341 ccggtcgaga acgtaggacg cttccaggcc gtcggacagc agctcttggt gggtgcgctg
    20401 cttagccctc gcatctgcct cgtccggtgc ccgcaggcac ccggcgacgt cggccaggac
    20461 cggcgggcgg ctggcttcgg cggcgcgttg atgggctcgg cggatggcga tgcgcaatgc
    20521 ggatcctgcg aattcgtcca gaggcttgcc caggccgagt tcgacaatgg tgcggagcag
    20581 ttcgatttgg cgcttgcctg cgatggccgg gtccatcgga ttgatgcagg aggaggttgt
    20641 tccgccgccg ggtgcgaact tcacgggagc gtgccccgtc aatgagcgcc cgagggccgc
    20701 ccattcgcct tcttcacgct ccttctgctc ctttgtgtcg aggacaacta ctttgcggcc
    20761 gagccggatt tgccgggcgg tataggtctt ggccagtgcg cttttgcccc gtccggtatc
    20821 gcccatgaag atcgcgttgc cgccgggcag cccgtcgccg aaggcgaaga aggggcagta
    20881 gatgaaggct ttgccagaat agagttcccg gccgatgacg gcgcccgcgg tacccagagt
    20941 gggaggcgcg atcggcagat agagggcctg gctggtggtg gtctccgtgt agagggggcg
    21001 tcggaccgtt tcgtgcagcg gtgtcagcgg tgcgaggtcg agaaggttgg tcacttgatg
    21061 cccccggcga acggaagggt gttggcgaat gccctcgcgt gctccagatc gagccattcg
    21121 atgcgcagat gggcgcttcg ggcgcgggag gcggtggtgc gtttggtccg cgccagctct
    21181 tccgcactcc gggcggagac gctgatgtac ccgacgaccg cggcaccggc cgcgccggaa
    21241 ctggcgagcg ccatgccgcg tgagctggtg gcgtcggagg cgatgcggtc gcgcgggtcg
    21301 acgttcctgc cgcgcgtggc gttgcggtgc atctcggcct ggttgttggt gtcctccctc
    21361 agcatgcgct cgacagccgc atcgttgggc tccaggttct gcgtgatcgc cacagtgcgg
    21421 atcacgtcgg gcatgccgat gagcagggga gagaggaagt cggggcccac gggcgtggtg
    21481 ggccatgacg tcacggcggc tgtcgcgtgg taccagctgc tggtggatcc ggcggcgcgg
    21541 gtcgccacgt gttcgccccc gcggacatcg acgttccggg ggaaggcatg cgcctggggc
    21601 agatgggtgt cccagatggc gtggtcggga tcgtagctgt tacggatgaa ggcggtgagc
    21661 ctgccttcgt caaggggggc aatcacggag aggtcggcgt cctcgcaccg ttcccatagt
    21721 tcttccatgt aggaacccat cgcggcggca atgccctcgt cgccggcacc gcgggccgac
    21781 gcgtcagcgg caaagtcacg actgaaccgt gcgtgcgcgg tgatgtagta ccggtgctcc
    21841 tcggcagagg tcgatacggc gttggccagc gtggcgtagg agtccttgag ccactggggg
    21901 gcgttggcgg tggcggcgga ttcgtcgcgc tgggcgatga accgctgatg cgcgctgggg
    21961 tcgctcttga gctggcgggc gagcacctga atgcgcttga ccgggtgctc ctccgtgttg
    22021 ccgaaggcat cgagcagccc gccccaccgc tccagggcca cttcctgctc gctgatctcc
    22081 ttgccgccga ggcccgggga ggcgacctcc agtgtggcgg tgacgcaccg ggatgcaggc
    22141 tgaagcacca cagtggcctt ctgcccccgt accgtcacag gcagccaggt cattccggcg
    22201 atgccttcgg gctcggcgag cgcggcgtcc ggcgcagtgc catccggccg gactccggcc
    22261 tcgatggcgg gagagaccca cacgccgcca gtcctctgta gggcctgacg gtggtatcgc
    22321 ttgatccgcc accagcggta cagggttcgc ctctgagcgg tgcctttggg ccggtacggc
    22381 gcgtagacga cgagcagcgc gagcgcgagg ggcgtgacca ggccgagccc ggccagcacg
    22441 ggaacagcgg agaacgcata gccgcaaacg agccccgcca cggcgccgca gccgagcacg
    22501 gcttgttcac ccaggtcccg gcgtccgacg aggcccgtag ggcggtgctt tccgaactgg
    22561 tacgtacgag cagtcatttg atcactggtc cttgccggtg gcgggcttgt gcgaagccgc
    22621 cgggccggac ggtttcgtgg gcatcgggat ggtggaggga ccagcaccgg aagtggtgcc
    22681 ggagctggcg gggggagccg ctggacgggg aggcggcggg ctggtggccg gtggccccgc
    22741 ggctgtcccc gagctgggtc cgacgaccga accggacggc gttccttgcg gacgtgctga
    22801 ggccggagca ctggaggcgg cacggctgct gtgctgcccg gtgctcgcac caccgctgga
    22861 cgccgcatcc ggcccctggg cccctggcga gctggccgcc ttgttcttcg caacgttcac
    22921 accggccttg actgctgccg ccgcaacacc caccggtccg gcagcagcag cgccgccgct
    22981 ggcgcccgag ccggccgcgg ccttggcgct ggccgtaccc gcctgcctgc cgcccaccgt
    23041 cgcggagttg gccgccttgc cgcccgttgt ctgcgcgctg tgcttggccc cggccgactt
    23101 gccgcctccc accagcgagt cctggatgtg cgtggacatc gccctgttca cgtgctgggc
    23161 aggaccgtcg accgcggcag cggggccgga ggaggaggcc gccttacggt cgtggtggag
    23221 ctgagccatc tcatcgccga aggacggcac ccatttgtag agcgtggcgg atgcgaagac
    23281 cgccagcagc aggatcagcg agcccacgag gatcttggag accgcatcgc tcatgctgcc
    23341 ggtcgagtcg ctgagaatcg cgccgccgag ccccagaagt gcgaagagca ccggtttcga
    23401 cagtcccagg gcgaggaggg caccgatcca cttcttgctc ttgccccaca ggtcccggtc
    23461 gaccaggccc gcgttgacca gtggtccgag tgcgacaccg acgtagatgg cggcaccgcg
    23521 gatgagcagc tcgatccaca tgagcaaagc cccggccagc atgaccaggt tgaccgtgat
    23581 gagctggccg aggccgtcac gggggttcaa ggccaagatc ttgagcaagt tggcgaggaa
    23641 aggcgtgaag ttcgccgtcg cgtacggttc gaagaccgct gtgacctcgt caatcgcccg
    23701 catgagcagt gcgatggcgc cgggggtgat ggcgttgaca acgaactgga gaacgaggaa
    23761 gcccaccgct tcggacgcag cggtgcccag ggaaacgccg cggacggccc gcttcgcgac
    23821 ggcgaccagc cacagggccg cggtgaacaa cgacgaggcc gcgaagatca tcgcgtactg
    23881 cttgaggaag ccgggactcg tcagatcgac cttggtcgag tcctggatca gctccagcat
    23941 cttgcgcagg aaccagatgt tcgcctcggt cagcttctgg agcaggaagc ccagagggtc
    24001 gctgacgaag tcgatcgccg ccttggcctc gcagacgaac gggatggcgc agaaggggtt
    24061 ggccaccgcc gacgggacga agacgaagcc gacggcgaca ttgacccaca cgaaggtgtg
    24121 cagtcgtcgg cccagggtgc cgcgcgaggg agttcgctcc accaccagca gaccgggggc
    24181 gtcgtcacgc aagcgcagac gcatcagcga cacctcccac gtcggcgaaa cggctggccg
    24241 gtgctgcctg ttctgcggcc ggaggcgagg gaaccagcgg ctcaccctga gtgaccgcag
    24301 tggtcttcca cgtgccgtcg acccagacga ggtcgacgtt catccgctga aaggccaccc
    24361 gcgggcgctc ggactcctcc gcgccggcga taccgccgac cgaagccgtc cacagttcga
    24421 cgctggcagc ctggtccgag ccggacaggg atcgcgtcgc caggacggcg gtccgtgtga
    24481 cgagctgccc gccgtccgcg gtctttccgt cgtcgccgag ctgacggttg tcggcgacca
    24541 gctgcgcggt ggagtccgcg tcctcggtaa ccgccgggcg gacggacggc gcagtcgtga
    24601 tggcgagcat gcggtggcgc caagcggcat cggtgaagaa ccgcgggtca ccgtagagca
    24661 cgacggcatt ggcggccgca gcacgagcgc ccccgctgcc acgggcatac gggccgggca
    24721 ggctgccttc atcggtaccc ctcaggacag gatcagcggc ctggccgggc acgtactcgg
    24781 agaagtccga agccgcattg gtggcctgct gggtggagag aggagccacg agcccggtac
    24841 ccgacgacag cgaagccacc ttccaatcac ccttttccca cagaaggttg acggtgaccg
    24901 actggaagcc agccttgggt ggggcgtgac cagcggcact tccccgcacc gtcgttgtcc
    24961 acaggcgaat tgccgacttg tggatatcga aggcgagcac ac
//
