LOCUS       NZ_NDXL01000001        20726 bp    DNA     linear   CON 27-APR-2024
DEFINITION  Streptomyces kasugaensis strain BCRC 12349 scaffold1, whole genome
            shotgun sequence.
ACCESSION   NZ_NDXL01000001
VERSION     NZ_NDXL01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces kasugaensis
  ORGANISM  Streptomyces kasugaensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 5071473)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Comparative genome analysis for kasugamycin overproduction
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5071473)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Comparative genome analysis for kasugamycin overproduction
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 5071473)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030,
            China
REFERENCE   4  (bases 1 to 5071473)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. May-2015
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 188.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002261115.1-RS_2024_04_27
            Annotation Date                   :: 04/27/2024 02:42:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,951
            CDSs (total)                      :: 7,863
            Genes (coding)                    :: 7,657
            CDSs (with protein)               :: 7,657
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 206
            CDSs (without protein)            :: 206
            Pseudo Genes (ambiguous residues) :: 0 of 206
            Pseudo Genes (frameshifted)       :: 87 of 206
            Pseudo Genes (incomplete)         :: 170 of 206
            Pseudo Genes (internal stop)      :: 23 of 206
            Pseudo Genes (multiple problems)  :: 65 of 206
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:37:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4542598
            Orig. end                         :: 4563324
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NDXL01000001.1.
            Bacteria and source DNA available from BCRC.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20726
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="27"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20726
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20726
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10726](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10726)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            complement(120..1004)
                     /locus_tag="B7024_RS19505"
     CDS             complement(120..1004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044542.1"
                     /locus_tag="B7024_RS19505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA thioesterase II"
                     /protein_id="WP_052853161.1"
                     /transl_table=11
                     /translation="MTNPAERLVDLLDLEQIEVNIFRGRSPQESLQRVFGGQVAGQALV
                     AAGRTTERDRPVHSLHAYFLRPGRPGVPIVYQVERVRDGRSFTTRRVVAVQQGRTIFNL
                     TASFHKPEPGFTHQLPMRRAVPGPEELPTIAEELRGHLGELPEALERMARRQPFDIRYA
                     DRLRWTPDEIEGAEPRSAVWMRAVGPLGDDPLVHTCALTYASDMTLLDAVRIPIEPLWG
                     RRGFDMASLDHAMWFHRPFRADEWFLYDQESPIAIGGRGLARGGIYDREGRLLVSVVQE
                     GLFRPRDSSVTEP"
     gene            complement(1057..3570)
                     /locus_tag="B7024_RS19510"
     CDS             complement(1057..3570)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572140.1"
                     /locus_tag="B7024_RS19510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_094792737.1"
                     /transl_table=11
                     /translation="MTLIDHLPKDADPDALFEAFSSWAEQQGITLYPAQEEALIEVVSG
                     ANVILSTPTGSGKSLVAAGAHFTALANDQVTFYTAPIKALVSEKFFDLCKLFGTENVGM
                     LTGDASVNADAPVICCTAEVLASIALRDGKHADIGQVVMDEFHFYAEPDRGWAWQIPLL
                     ELPQAQFILMSATLGDMSRFEGDLTRRTGKPTSVVRSVTRPVPLSYEYRTTPMTETLTE
                     LLETHQSPVYIVHFTQAAAVERAQALMSINMCTRAEKDQIAQLIGNFRFTTKFGRNLSR
                     YVRHGIGVHHAGMLPKYRRLVEKLAQAGLLKVICGTDTLGVGVNVPIRTVLFTALTKYD
                     GTRVRTLRAREFHQIAGRAGRAGFDTAGFVVAQAPEHVVENEKALAKAGDDPKKRRKVV
                     RKKAPEGFVNWGENTFEKLIASDPEPLTSRFRVTHAMLLSVIARPGNAFEAMRRLLEDN
                     HEPRKNQLRHIRRAIAIYRSLLDGGIVERLAEPDAEGRIVRLTVDLQQDFALNQPLSTF
                     ALAAFDLLDPESPSYALDMVSVVESTLDDPRQILAAQQNKARDEAVAQMKADGVEYEDR
                     MERLMDVEYPKPLEELLFHAYNLYRKNHPWVGDHPLSPKSVIRDMYERAMTFTEFTSFY
                     ELARTEGIVLRYLASAFKALDHTVPDDLKSEDFQDIVAWLGEMVRQVDSSLLDEWEQLA
                     NPAEETAEEAAERADQVRPVTANARAFRVLVRNAMFRRVELAALDKVEELGEMDAESGW
                     DADAWGDAMDAYWDEYDELGTGPDARGPKLLLIEEDAEHGLWKVRQTFADPNGDHDWGI
                     SAEVDLAASDEEGRAVVRVTDVGQL"
     gene            complement(5272..5793)
                     /locus_tag="B7024_RS19515"
     CDS             complement(5272..5793)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979215.1"
                     /locus_tag="B7024_RS19515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6624 domain-containing protein"
                     /protein_id="WP_094792738.1"
                     /transl_table=11
                     /translation="MAHENITALAAELINMAAADQQNSYRANDEDPAEQLAWRRLTARH
                     GDRLNEIMDEYGWPTAELVGDNAARGAWLIAQHADRQLGIQRRALQLMEQAVATGSASP
                     RELAFLRDRTLVNDGHKQVYGTQIAGIKDGSPVPWPCEQPQHMEKLRAEVGIEPFAEYT
                     AKYTDKISTT"
     misc_feature    5906..5924
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 21.82"
                     /tool="antismash"
     gene            6566..7159
                     /locus_tag="B7024_RS19520"
     CDS             6566..7159
                     /EC_number="1.-.-.-"
                     /EC_number="1.4.3.5"
                     /GO_function="GO:0004733 - pyridoxamine phosphate oxidase
                     activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639247.1"
                     /locus_tag="B7024_RS19520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_052853164.1"
                     /transl_table=11
                     /translation="MGKSYERIDGRLRAFIEAQHIFFTATAPLDGDGTVNLSPKGLNGS
                     FAVLDELTVAYLDFAGSNAETVAHLRENGRITLMWCAFDGPPNIVRVHGHGEPVFRDDA
                     RWNELMGYFPDIDPTTHGLRAIIVVTAEKIRDTCGYAVPFMTYDGDRPLHASRFARETD
                     ESLDVYFQKKEDIATSIDGLPGLPLPLPPLPRTA"
     gene            complement(7831..8112)
                     /locus_tag="B7024_RS19525"
     CDS             complement(7831..8112)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380306.1"
                     /locus_tag="B7024_RS19525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_205380085.1"
                     /transl_table=11
                     /translation="MYAALALTIGASGLAAPSASAASAAAPAPKLPSVSVLGELDSLGV
                     TPVPAAYRGQLPTVTGQLMGLQHLHDLSELHQLTDLVAPVTGLLPTLA"
     gene            8458..9237
                     /locus_tag="B7024_RS19530"
     CDS             8458..9237
                     /NRPS_PKS="Domain: PKS_KR (16-182). E-value: 1.6e-14.
                     Score: 46.2. Matches aSDomain:
                     nrpspksdomains_B7024_RS19530_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006608143.1"
                     /locus_tag="B7024_RS19530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_094792739.1"
                     /sec_met_domain="adh_short (E-value: 3.1e-30, bitscore:
                     103.5, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.8e-30, bitscore:
                     104.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTQAYLSEMFSLDGRVAMVTGGSSGIGRAVAEALACAGAGVVIV
                     ARKAAELAAAADELTAHGCRAAWVSADLGTRDGVRAAAEGVVDAFGEPDILVNCAGINL
                     RPPMGELGEDVWDTTMAVNLEAPYLLGQRFGPGMAERGFGRIIHITSQQAHRAFVQSGA
                     YGVSKGALESLARSQAEAWSPHGVTCNTLVPGFVMTPLNARLSSDPEKVAALAERTMVG
                     RNGLAEDFAGAAVFLASGASAYVTGQAIFVDGGFSVH"
     aSDomain        8506..9003
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B7024_RS19530_PKS_KR.1"
                     /evalue="1.60E-14"
                     /label="B7024_RS19530_PKS_KR.1"
                     /locus_tag="B7024_RS19530"
                     /protein_end="182"
                     /protein_start="16"
                     /score="46.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAMVTGGSSGIGRAVAEALACAGAGVVIVARKAAELAAAADELTA
                     HGCRAAWVSADLGTRDGVRAAAEGVVDAFGEPDILVNCAGINLRPPMGELGEDVWDTTM
                     AVNLEAPYLLGQRFGPGMAERGFGRIIHITSQQAHRAFVQSGAYGVSKGALESLARSQA
                     EAW"
     CDS_motif       8515..8652
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B7024_RS19530_0001"
                     /evalue="2.30E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="B7024_RS19530"
                     /protein_end="65"
                     /protein_start="19"
                     /score="17.0"
                     /tool="antismash"
                     /translation="VTGGSSGIGRAVAEALACAGAGVVIVARKAAELAAAADELTAHGC
                     R"
     gene            complement(10001..10726)
                     /locus_tag="B7024_RS19540"
     CDS             complement(10001..10726)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04539.1"
                     /locus_tag="B7024_RS19540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_094792740.1"
                     /sec_met_domain="CDPS (E-value: 2.4e-68, bitscore: 228.1,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQSYPLLTTPDSKMYVEPLSDRSRLIWQRGEHALIGVSAGNGYFN
                     QDRLTVLMEWAEDSFAKVDVVYVDTHIDSMLIADGRVPESAIRSVKATLKDVRRRIRRA
                     LERLGPEAARFRVRALSEIMELPIYRTVEKQTDRAIEEDEEFSSICETMVHEIVQHRPG
                     GGSDVTAEQVHAGLSYLKAEAPLFVDSPSIFGVSTSVLLYHTRTPVSQHLAQQTTGFCA
                     AQGQAYVVVSPPSLAASDT"
     misc_feature    complement(10706..10708)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10749..11069)
                     /locus_tag="B7024_RS19545"
     CDS             complement(10749..11069)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471397.1"
                     /locus_tag="B7024_RS19545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6092 family protein"
                     /protein_id="WP_094792741.1"
                     /transl_table=11
                     /translation="MKSGEKTLPQDRLHEEIALLAAYLLSSGRGLLDEPADYGAYRCAD
                     AARRTLGILEQAGASTPQLSGIRHRLDEIMFSPMGGDLHLPEILDDLCLQLAGALKELK
                     TA"
     gene            complement(11026..11643)
                     /locus_tag="B7024_RS19550"
     CDS             complement(11026..11643)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159: dihydropteridine reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572569.1"
                     /locus_tag="B7024_RS19550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitroreductase family protein"
                     /protein_id="WP_094792742.1"
                     /sec_met_domain="PF00881 (E-value: 5.2e-11, bitscore: 40.9,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKISSPEVPAETPTRTLPVTLPETLNVLRSRSVVRNYAPDRVDD
                     SLIEQLLECMLAAPTASNKQAWSFVVVREPAGVRLLRAFSPGIIGTPAFVVVACLDRRL
                     TDGLSGNISQKIYQTSKLCVAMAVENLLLSAHALGLGGCPVSSFREEAVRLLLDLPTPI
                     EPILMVPIGRPAQKLTPSERRDKNEVISYEIWGKDAATGSAA"
     misc_feature    11626..11642
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.65"
                     /tool="antismash"
     misc_feature    complement(11748..11761)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.04"
                     /tool="antismash"
     misc_feature    complement(12092..12107)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.67"
                     /tool="antismash"
     misc_feature    complement(12838..12850)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.83"
                     /tool="antismash"
     gene            complement(13136..13909)
                     /locus_tag="B7024_RS19555"
     CDS             complement(13136..13909)
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179: hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020557889.1"
                     /locus_tag="B7024_RS19555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAD family hydrolase"
                     /protein_id="WP_094792743.1"
                     /transl_table=11
                     /translation="MFSLRARTVVFDIDGTLCFDGRTIDEEILAALGECERAGHHLVFA
                     SARPVRDLLPVLNGAFASATLIGGNGSLVSAGGQVRARAAFDPAGLRALLEAAGRYEAT
                     YLADGPWDYAYTGPVDHPIRSRVDQGDLARRVDLTELPEVVKFLVVGASDMTELAETGR
                     RLGLTVNHHLDEAIIDFAPGSTTKWEALASMEIREYVAFGNDINDFDLLRNAERAVRVG
                     AHPSLDDVAQVTVAADPVAVAAEISLLAQAAGVVV"
     gene            14299..15024
                     /locus_tag="B7024_RS19560"
     CDS             14299..15024
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020207307.1"
                     /locus_tag="B7024_RS19560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VWA domain-containing protein"
                     /protein_id="WP_052853172.1"
                     /transl_table=11
                     /translation="MTSPAISLTKVQERAPGLVSLYKSAAVSLRKRSLQGVRAAVYLVL
                     DRSGSMRNYYKDGTVQHLAEQVLGLSAHLDDDGTVPVIFFSTDIDGTAELDLGNYQGRI
                     EELHSGLGHMGRTNYHWAMDEVIDHYLASGSSAPALVIFQTDGGPTSKFAAERYLCKAA
                     TLPIFWQFVGFGDPDEQEFAFLHKLDDLPVPAKRVVDNAGFFHAGRDPRSVSDDVLYDE
                     LLHEFPSWLTAIDSAGSMQ"
     gene            15038..15496
                     /locus_tag="B7024_RS40770"
     CDS             15038..15496
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS40770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_143682150.1"
                     /transl_table=11
                     /translation="MTRDSAPRVRGGDGAAAGAGPAGGLRVYGVSAAVEGQGTGRRGDP
                     GAGHGGTVPGSPDVRLRDYVHGYVGFGPTMGLPAVQRVLPEVAVMLVLDFVARPSRLVT
                     AEGGAARMPSLPVIGLHDRPVLVEHGGSPRGVAIGLTPPGAMPCSASR"
     gene            15493..15975
                     /locus_tag="B7024_RS19570"
     CDS             15493..15975
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /locus_tag="B7024_RS19570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_094792745.1"
                     /transl_table=11
                     /translation="MSELANTYTSLADLVGGRAWCLVEQLSQLSHWQARFTLLDRTLAQ
                     WLAGTNAPAATVLRAWRRLTESAGRLTIAGLSDELGCSRRYLEMRFGEQVGLPPKTAAR
                     ILRFKSAARILTAAGGGSFSEIAGRCGYSDQAHLNRDFRALAGCTPTEFLLRRSSG"
     misc_feature    15532..15534
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16350..17717)
                     /locus_tag="B7024_RS19575"
     CDS             complement(16350..17717)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061444.1"
                     /locus_tag="B7024_RS19575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M64 family metallopeptidase"
                     /protein_id="WP_094792746.1"
                     /transl_table=11
                     /translation="MLRRTSICASTRTSARATPRISLRTSLRTAAAVGLAAVALTAAAT
                     STAQGATPPPDPQGQPTQQVEYFTGPGGHPRHTTIPASKPLSRSAKAAPAPDGQVTPIV
                     QNGPVGTKLDVVFIGDGYTAAQQATFHADVRAKWAKMTAVEPYASYTGLFNVWAVDAVS
                     RQSGVSGDPDRNAVRDTALGSAFFCDDIERLLCVDTGKVESYAAKAPAADLVVVLANST
                     KYGGAGYNDISSKVGYDGIATASAHNADAVQIAIHETGHSLGKLADEYDYGQSGTYSGP
                     EPGSANITTYTVDQMTTRKQKWYRWMGQKSPDGGTVGAYEGGGYYQFGLNRPTENSIMR
                     TLGREFNLPGREAMIAGFYRHASVLSSPVAAGRTLSRGDRIPVTLPASAQVKWYVDGRE
                     AKAWRGKTTVVPRSLGVPSDGRAHTVTAKAVDGTDAVRDPALRKPLSASLSWQVTR"
     gene            18042..18737
                     /locus_tag="B7024_RS19580"
     CDS             18042..18737
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF017760.4"
                     /locus_tag="B7024_RS19580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_094792747.1"
                     /transl_table=11
                     /translation="MIALLRHRAFRNYWIGQSISLVDEEISRIALPLAAVLILDAQAGE
                     MGGLTTTALVPALLFSVPAGAWVDRWRSRRRVMPVTNLGRFLLMASIPAAYAWGVLDFV
                     QLCLTAFAIGALGVLFNVCDSTLYVSLVPAKSYFQSSSLMNGSRSLAFTAGPSLGGLLV
                     QFARAPFALFVDALSYLLSALFLFRISPAEPPPSAWRRGHFTAGLKWLVRAPLMRPMLA
                     AVARLNFKR"
     misc_feature    18054..18056
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(<18725..18922)
                     /locus_tag="B7024_RS19585"
                     /pseudo=""
     CDS             complement(<18725..18922)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105907.1"
                     /locus_tag="B7024_RS19585"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSDRMGGPKRQDPEAEVALDAKGLRALAHPVRVQLVELLRTYGPS
                     TATRLAARLGITSGNASYRLK"
ORIGIN
        1 gtcaacctct cccgggcact cgccaccgcc cgcagagacg ccccggcgcg cccgcgggaa
       61 gcgacctcgg cccgccgccg tcccccgggc ttcgcgaacc acccatcccg gaccgggact
      121 tacggctcgg tgaccgagct gtcgcgcgga cggaaaagcc cttcctggac aaccgagacc
      181 agcagcctgc cctcccggtc gtagatccct ccgcgggcca gacctcggcc gccgatggcg
      241 atcggcgact cctggtcgta gaggaaccac tcgtccgcgc ggaacggacg gtggaaccac
      301 atcgcatgat ccagagaggc catgtcgaac ccgcgccgcc cccagagcgg ctcgatcggg
      361 atccggacgg cgtccagcag tgtcatatcg ctggcgtagg tcagcgcgca ggtgtgcacg
      421 agcggatcgt cacccaacgg cccgaccgcg cgcatccaca ccgcactgcg cggctccgca
      481 ccctcgatct cgtccggcgt ccagcgcagc cggtcggcat aacggatgtc gaacggctgc
      541 ctgcgcgcca tccgctccag cgcctcgggc agttcgccca ggtgcccacg gagctcctcc
      601 gcgatcgtcg gcagctcctc cgggccgggc accgcccggc gcatcggcaa ctgatgagtg
      661 aagccgggtt ccggcttgtg aaaggaggcg gtcagattga agatcgtgcg tccctgctgg
      721 acggcgacga cccggcgggt ggtgaaggac cggccgtcgc gtacccgctc gacctggtac
      781 acgatcggca ccccgggccg ccccggccgc aggaagtacg cgtgcagcga gtggaccggg
      841 cggtcccgct cggtggtccg cccggcggcc accagcgcct ggcccgcgac ctgcccgccg
      901 aagacccgct ggagggactc ctgcggactg cggccacgga agatgttcac ctcgatctgc
      961 tccagatcca gcagatcgac cagtctctcg gcagggttgg tcatgaccgg cggtcctccg
     1021 tcacatccgt cgacggcctc cgatgaagcc gttccctcac agctgaccca catcggtgac
     1081 gcgcaccacc gcgcgcccct cctcgtcgga ggcggcgaga tccacctcgg cggagatgcc
     1141 ccagtcgtga tcgccgttcg gatcggcgaa cgtctgccgc accttccaca ggccgtgctc
     1201 ggcgtcctcc tcgatcagca gcagcttcgg gccgcgcgcg tccggaccgg tgcccagctc
     1261 gtcgtactcg tcccagtagg cgtccatcgc atcgccccag gcatccgcgt cccagccgga
     1321 ctcggcgtcc atctcaccga gctcctcgac cttgtccagc gccgccagtt ccacccggcg
     1381 gaacatcgca ttgcgcacca gtacacggaa cgcgcgggcg ttggcggtca ccggccggac
     1441 ctgatcggcc cgttcggcgg cctcctcggc cgtctcctcc gccgggttgg caagctgctc
     1501 ccactcgtcc agcagactgg agtcgacctg ccgcaccatc tcgcccagcc aggcgacgat
     1561 gtcctggaag tcctcggact tcagatcgtc cggcacggtg tgatccagcg ccttgaacgc
     1621 actcgccagg tagcgcagca cgatcccctc ggtgcgcgcc agctcgtaga aggacgtgaa
     1681 ctccgtgaag gtcatggcgc gttcgtacat atcgcggatg accgacttcg gcgacagcgg
     1741 atggtcgccg acccacggat gattcttgcg gtacaggttg tacgcgtgga agaggagctc
     1801 ctccagcggc ttggggtact cgacgtccat gagccgctcc atgcggtcct cgtactcgac
     1861 gccgtcggcc ttcatctggg cgaccgcctc gtcccgggcc ttgttctgct gcgcggccag
     1921 gatctgccgc ggatcgtcca gcgtggactc cacgaccgag accatgtcca gggcgtagga
     1981 cggcgactcg gggtcgagca ggtcgaacgc ggccagcgcg aaggtggaca gcggctggtt
     2041 gagcgcgaag tcctgctgga gatcgacggt cagccggacg atccgcccct ccgcgtccgg
     2101 ctccgccagg cgctccacga tcccgccgtc cagcagcgaa cggtagatcg cgatcgcccg
     2161 ccggatgtgc ctgagctggt tcttacgcgg ctcgtgattg tcctccagca gacggcgcat
     2221 cgcctcgaag gcattgcccg gccgggcgat caccgacagc agcatcgcgt gcgtgacccg
     2281 gaaccgcgag gtcagcggct cgggatcgga ggcgatgagc ttctcgaagg tgttctcacc
     2341 ccagttgacg aagccctccg gcgccttctt gcgcacgacc ttccggcgct tcttgggatc
     2401 gtcacccgcc ttggccagcg ccttctcgtt ctccaccaca tgctcggggg cctgcgcgac
     2461 gacgaacccc gcggtgtcga agccggcccg ccccgcgcgc cccgcgatct gatggaactc
     2521 ccgcgcccgc agcgtccgca cccgggtccc gtcgtacttc gtcagcgcgg tgaacagcac
     2581 cgtgcggatc gggacattga cgcccacgcc gagggtgtcc gtaccgcaga tgaccttcag
     2641 cagacccgcc tgcgccagct tctcgacgag ccggcggtac ttcggcagca tgcccgcgtg
     2701 gtgcacgccg atgccgtggc ggacgtaacg cgagaggttg cggccgaact tggtggtgaa
     2761 ccggaagttc ccgatgagct gcgcgatctg gtccttctcg gcacgcgtgc acatattgat
     2821 gctcatcagc gcctgcgccc gttccacggc ggcggcctgc gtgaagtgca cgatgtagac
     2881 cggcgactgg tgggtctcca gcagctcggt gagcgtctcc gtcatcggtg tcgtgcggta
     2941 ctcgtacgac agcggtacgg gccgggtcac ggagcgcacg accgaggtcg gcttcccggt
     3001 ccgccgggtc agatccccct cgaaccgcga catgtcgccg agcgtcgccg acatcaggat
     3061 gaactgggcc tgcggcagtt ccagcaacgg aatctgccac gcccagccgc ggtccggttc
     3121 ggcgtagaag tggaactcgt ccatcacgac ctggccgatg tcggcgtgct tcccgtcgcg
     3181 cagcgctatc gaggcgagca cctcggccgt acagcagatg accggtgcat cggcgttgac
     3241 ggacgcgtca ccggtgagca tcccgacgtt ctcggtgccg aacagcttgc acagatcgaa
     3301 gaacttctcc gacaccagag ccttgatggg cgcggtgtag aaggtgacct ggtcattggc
     3361 gagggcggtg aagtgcgcac cggccgccac caggctctta ccggagccgg tgggcgtgga
     3421 caggatgacg ttcgcccccg agaccacctc gatcagcgcc tcctcctggg cagggtagag
     3481 cgtgatcccc tgctgctcgg cccagctcga aaaggcttcg aagagggcat cggggtcggc
     3541 gtctttcggc aaatgatcga tgagggtcac accccctata gtgcctgcct tcgacccgca
     3601 tcagggaacc ggcgacccat atcgagatca tgcgacccgg cgacccgctg acctgtggta
     3661 acggctaccg catggtgtct gagctgccga gatgccgttt cccgtagcac gggctcagga
     3721 gcctcggacc acctcaaggc tccacctgac gcaaggcccg agaaggggcg cagggatcgc
     3781 cggacgagcg gggcggccgg gggcgcgggg atgagggtgc tgagccagtt tggatacgtg
     3841 ggctgacctg cggaaatgtg tcccatgggc gttggtcgac acgtctctgg ggcctatgtg
     3901 gaatgtgggg gagaggagtg aatggggcat tttcaccccg ctggatacca aggacctcag
     3961 tgcccctgtc cccccgtctc cagctccctg gggctgtctg tcttctcccg ggcaatcctc
     4021 gttcttcgga ccttgcggca ggcggggcag ggggacggcg tcgggtcgga ggaggttccg
     4081 tcggtctgcg gggagtggcg gagatcaccg tgggcgtggt ggcgcgcgag ccctgcccac
     4141 cggagctgga cgaggtgagt gcggaggcgc tcctcgggat gcgcatcccg aggagcagac
     4201 acccgtcctg gccggcccgc aggccaccgg cgctgccacc gacaccggat ggagtcggtc
     4261 ggcgtcgatg ggaatggttc gccgggcgtg gtcgatcacg gagatcggtg cgtcggcccg
     4321 ctgggaaatg cgtccagccc tcggtgcagt cggtcctctg cgaaaggagg cgtgatccac
     4381 tcggctggtg cctgccgtgg gaactggtgc ctgctgtggg agaggggtgc ctcggcgcgg
     4441 taggggcggt gggagcacac aaggcgcggg acgcaggggg cgggagggcc agggcgcgct
     4501 ccacggtgag gcgtcgctgt ctcgcgcatc aggcggcagt gcggtagaga ggcggcgggt
     4561 gacgtgcggg acacgctctc gtacgggtat ctgcgctgtg ggcatgggca tgggcatggg
     4621 catgggcgtg ggcgtggggg gtggaggcgg gggaggggag gggggagaga agagtagggg
     4681 gcgcaggcgg aactggggcc gaggcggtgc cgcgcccaaa accgtcgatc ctggcgacgg
     4741 cctattccgc ctcggccaca gcagtgccca tcgaatgcgc attgaatcgg cgtcggccgc
     4801 atccagcagg atggtgcgga cccggtccgg cgtgcgcgtc atcaaatcgg cgacgctgta
     4861 gatccctcag agcggtgtag atccctcaga gcattggaga gctcctgagc gctggagaaa
     4921 tcccgaacgt aggagaccta ccgagcgtcg gtcccacggc cgtatgtgtg agggccgctc
     4981 ggtcgacatg tgtgacggcc gccgcggtgt gtttctgtcc gaggccggaa ctggtcccgg
     5041 cgatgagccc agtttcggcc ccgccgggcg ctcggtcgca ccgcgtgctc atcgcgctca
     5101 tctttcctgt tgcgcgatcc ggggtcttcg atcctgacgg caccggtgtt cagcctgcgc
     5161 ggtcgatgtt gtgcggtagt cgacggctcg cggaggcagg ggcctgtggg ccttgccaag
     5221 agcggccggg attcggggtg cggtccggcg cgcccggctc agggtgacgg atcaggtggt
     5281 tgagatcttg tcggtgtact tggcggtgta ttcggcgaag ggctcgattc cgacctccgc
     5341 ccgcaacttt tccatgtgct ggggctgttc acagggccac ggaacaggcg aaccgtcctt
     5401 gatgccggcg atctgtgtgc cgtagacctg cttgtgcccg tcgttcacca gcgtccggtc
     5461 acgcaggaac gccagttcgc gggggctggc tgagcccgta gccactgcct gctccatgag
     5521 ctggagtgcc cgccgctgta tgccgagctg ccggtcggcg tgctgtgcga tcagccaggc
     5581 gccgcgcgcg gcgttgtcac cgaccagttc cgcagtcggc cagccgtact catccatgat
     5641 ctcgttgagt cggtcgccgt gccgggcggt gagccgccgc catgccaatt gctcggcagg
     5701 gtcctcgtcg ttggcgcggt atgagttctg ctggtccgcc gcagccatgt tgatcagttc
     5761 cgctgccaat gcggtgatgt tttcgtgagc cactgtcaac tccttggttc aggtgggaac
     5821 gtcatgtcgg tccacaacat tagaggcgta tttcgccgtg aagatcattc ggtggaacgg
     5881 tgacagaagt gcccgtgcgg agggatactg gatctactcc cagaagcgac acggcgttgt
     5941 ccgcaggcgg cacagcaatt cccgtacgta ggctcgcggc cacagttgga cggcggagag
     6001 aagacagttg tcccggggca gtgcacgttc cttctttggc ggtcgcccac acgtcgcatg
     6061 gcgcaaaagt gccttggtcg tagctgctgg gggcgattgg cggcgggcat gtcgctcaag
     6121 ttccgggcgg tcgatactcg atcggcgtgg cgttcggcgg tacggccttt gtcgccaggg
     6181 tggaggggcg tacgggtgca gcggcggggc gatttatggc aaatcgcgcc cgtaccggca
     6241 ggtgcaccgg gttggtccga agccgggcgc tgcgacttcg cgctttcccc ggggactggt
     6301 tgcacgacca cccgtccccg gtcgggcagt atcgctactc gtcgccgctg acgccgactg
     6361 cggtgttcac ggcgcttcgt aaccaggccg cttcggtgaa accctcggca taatcgtcaa
     6421 gacttgtgga tcaggtgcga ggcgcgccgc tcatgccgtc cagccgatcg tgatgtgtgc
     6481 cggcggtggt ccattccatt ggtccgtgat ccccgcgatc cccgcgtcct gccgcatggg
     6541 agggatcgcc cgccataatc gacctatggg aaagagctac gagcggatcg atggcaggct
     6601 gcgtgccttc atcgaggcgc agcacatctt cttcaccgcg acggcgccgt tggacggaga
     6661 cggcaccgtc aacctttcgc ccaagggcct gaacggctcc tttgccgtgc tcgacgaact
     6721 caccgtggcc tacctcgatt tcgccggcag caatgccgag acggtcgccc atctacgcga
     6781 gaacggccgc atcaccctga tgtggtgcgc cttcgacggt ccgcccaaca ttgtgcgcgt
     6841 gcatgggcac ggagagccgg tcttccgcga cgacgcgcgt tggaacgagt tgatggggta
     6901 ctttccggac atcgacccga ccacacacgg cctgcgcgcg atcatcgtcg tgaccgccga
     6961 gaagatccgt gacacctgcg ggtacgccgt cccgttcatg acgtacgacg gagatcggcc
     7021 gttgcacgcg tcgcgcttcg cgcgcgagac cgatgagtcg ctcgatgtgt acttccagaa
     7081 gaaggaggac atcgcgacca gcatcgacgg cctcccgggg ctgcccttgc cgctgccgcc
     7141 gcttccccgc acggcctaac agccagccgg tggagcggac accacggcgg gcgggctctg
     7201 ttcgggagac tgtcatgccg cccggaactc cccgcgttcg gtggggaggc cgtgctcgaa
     7261 gagggtcccg gcgtcggcga gggcgatgag gcgggggtgc gttcacggct cttctgtggt
     7321 tctgggcgga ctgggccagt cgagcacatt gctgtggtgt gacgggcctt ctgtagcgca
     7381 ggagggatgg tcctgcctcg atcctcggtg agtccggcct cttcgcgggg atggcaggcg
     7441 gtacgggagc gcgagctgtg gcgactgcca ccgtagggat cggacacggg cacggacgtg
     7501 gaggcaggcg tggaggtgga tgtcgagccg aggttgttga ggtagctgag gccgttgccg
     7561 gaggatcccc gggggctgag gttcgtcggc cggggcggag tgggaggccc gcagtggccg
     7621 ataccactgg gcctcgcgca tagctaccgg ccgggagggc ggcagctggg tccggttcag
     7681 ggcctccctc tgactcttca ccggcccgag ccggtccccg atctcggccc gcgccggtcc
     7741 cccggccccg acaccgcgcc gggggaccgg tggtatcccg gacccccggc gtcggatgac
     7801 gtaacacaag ccgccggcgg cgcggaaggg ctacgccagg gtcggcagca ggcccgtcac
     7861 cggggccacg aggtccgtca gttgatgcag ctcgctgagg tcgtggagat gctggaggcc
     7921 catgagctgg ccggtgaccg tcggcagctg gccccggtat gccgcgggga cgggggtgac
     7981 gccgaggctg tcgagttcgc cgagcacgga cactgaaggg agcttagggg cgggcgcggc
     8041 ggcggaggcg gccgaggcgg acggtgccgc caggccggat gcgccgatgg tcagggcgag
     8101 cgctgcgtac atacgtcgag ttgagatcac gctttcacaa ccggtcgggg gcgccgacgg
     8161 acacgggata ccggtggcat catccggctg gccggtgccc cggagcgaag gccggggcgc
     8221 tcgccgctgg tgagacccca gacgctccag caccagatcg ccgcaccgcg cagcgacgcc
     8281 ggagtcgacg atgaagacct ggctgggcgg tgagcagagt cccatcctcg gtgggtgccg
     8341 ggtgccgccc gactgttttc gatcggacgc cgccgggtga ggacgccgct ccggccgtgg
     8401 cgacatcccg gttgacgtgc tgtccggcgt cgcggacgcg ctgtctagtg tgcagtcatg
     8461 acaacgcagg catatctctc cgaaatgttc tcgctggacg gccgggtggc catggtgacc
     8521 ggcggcagtt caggtatcgg ccgggctgtc gccgaggccc tcgcatgtgc gggggccggc
     8581 gtcgtgatcg tggcacgcaa ggcggcggag ctcgccgccg cggccgacga gctgacggcc
     8641 catggctgcc gggcggcctg ggtgagtgcc gacctgggca cccgcgacgg cgtacgcgcg
     8701 gcggccgagg gagtggtcga cgcgttcggt gagcccgaca tcctcgtcaa ctgcgccgga
     8761 atcaacctgc ggccgccgat gggcgagctg ggcgaagacg tgtgggacac cacgatggcg
     8821 gtgaaccttg aggcgcccta cctgctgggg cagcggttcg gtcccggcat ggccgaacgg
     8881 ggcttcggac ggatcatcca catcacctcc cagcaggcgc atcgggcgtt cgtccagagt
     8941 ggtgcctacg gtgtgtccaa gggagcgctg gagtcgctgg cccgttcaca ggccgaggca
     9001 tggtcgccgc acggcgtcac ctgcaacacc ctcgtaccag gtttcgtcat gacgccgctc
     9061 aacgcgcgcc tctcgtccga ccccgagaag gtcgcggcgc tggccgagcg cacgatggtc
     9121 gggcgcaacg ggctggcgga ggacttcgcg ggcgcggcgg tgttcctggc gagcggtgcc
     9181 tccgcctatg tcaccgggca ggcgattttt gtcgacggtg ggttctccgt tcactgaatc
     9241 cgacagggga ggcgggtggg gctgggggcc gtccgggtgt gacggcctgc gccgtcgtgc
     9301 ggtcagtcgt ccaccggctg tgcctccccg ccgatgcgga cggcacacgg gtgctgccgg
     9361 ggcgggaggg tttcgccaca gcggtcgcag actgtgcgtg gccggagcac ggtgccgcag
     9421 tcgtgctccc atgccgtcgg gggctctccg ctggtcgcgt acggccgccc agcccatgag
     9481 gccgcgcagt acgggctgca atgcgcggcc cgcccgcttc ggtgggtacg tattcgtagc
     9541 gtggtgggtg ctcctgtacc gctctttggc caggacgccg gactcgacga gtcctcatca
     9601 gccggctggc gagaatgtcc cggccgacac cggtgtgcgc ggcgatccgg tcgaaccggt
     9661 gcactccgca gaaggctttt cgcaacgcga cgagactcca gtgttcgccg atgatgccga
     9721 gggcgatggc gatcgggcag ggcgatatcg gatgcagagg ttcgacaccg atcgccctcc
     9781 gtctgccggt gccatgccgc caaggccccc gtccggcctt ctatgccgat gccgatgccg
     9841 atgccgacgt gggctgtggg tgggcgccag gtgagcgacc gggacgggtc gggtcgggta
     9901 tgcgtcgtgt cggcctactt ctgccgtccc ggcctgctgg gctgcgcgtg cggagttgcc
     9961 ggccgagggt gtgtgcaaca ggtcggccga cggcgccgtc tcatgtgtcg gaggcggcca
    10021 gcgagggggg gctgacgacg acgtaagcct gtccctgcgc ggcgcagaac cccgttgtct
    10081 gctgggcgag atgttgggag acaggagttc tcgtgtggta caggagcacc gaggtggaga
    10141 cgccgaagat gctcggagaa tccacgaaga gcggggcttc ggccttgagg taactcagtc
    10201 ccgcgtgcac ttgctccgca gtgacgtcgc tgccgccgcc cggccggtgc tggacgatct
    10261 catgcaccat ggtttcgcag atcgaggaga actcctcgtc ctcttcgatg gcccgatccg
    10321 tctgcttttc cacggttcgg tagatcggca gctccatgat ttcggagagg gcccggacgc
    10381 ggaatcgtgc ggcttcgggg cccagcctct ccagtgcccg ccggattctg cgccgtacgt
    10441 ccttcagtgt ggctttcacc gaccgtatgg cgctttccgg gacacggccg tccgcgatga
    10501 gcatcgagtc tatatgggtg tcgacgtata cgacatcgac tttggcgaaa gaatcttccg
    10561 cccactccat caagacggta aggcggtcct ggttgaaata gccatttcct gcgcttacgc
    10621 ctatgagtgc atgctcgccg cgctgccaga tgagccggct tctgtcgctg agcggctcga
    10681 cgtacatttt gctgtctggc gtcgttaaga gcggatagga ctgcatggcg gatcttcttc
    10741 ctttcctctc aggcggtttt gagttccttc agggcgccgg ccagttgtag gcagagatcg
    10801 tccaggattt cggggagatg cagatcgccg cccatcggcg agaacatgat ctcgtccagg
    10861 cggtgtcgaa tcccggacag ctggggagta ctcgccccgg cctgctccag aattcccagc
    10921 gtccggcggg cggcgtctgc gcaacgatag gcgccgtagt ccgccggctc gtccaggagc
    10981 ccccgtccgc tgctcagcag ataggcggca agaagggcga tttcctcatg cagccgatcc
    11041 tgtggcagcg tcttttcccc agatttcata gctgattacc tcgttcttgt cgcggcgttc
    11101 ggagggtgtg agcttctgtg cgggacggcc gatggggacc atcaggatcg gttcgatcgg
    11161 ggtcggcaga tcgagcagga gccgcaccgc ctcttcccgg aagctgctta cggggcagcc
    11221 gcccagtccc agcgcgtgcg cggaaaggag gagattctcc accgccatgg ccacgcagag
    11281 ctttgaggtc tggtagatct tctgtgaaat attgccggag aggccgtccg tgagacgcct
    11341 gtcgagacat gccaccacga cgaatgcggg cgttccgatg atccccggag agaatgcccg
    11401 caggagtcgc acgccagccg gttcccgcac cacgacgaag gaccacgcct gtttgttgga
    11461 cgcggtgggt gcggcgagca tgcattccag cagctgctcg atgagcgagt cgtcgacccg
    11521 gtcgggtgcg taatttcgga ccacgctccg cgagcggagc acgttcagtg tttccggcag
    11581 cgttaccgga agtgttctcg tcggtgtttc cgccggtact tccggtgagg aaattttcgg
    11641 catcacttcc ctttctttcg ggcaacccct tggccaccgg gggatctcgg cgatatctcg
    11701 gcgggattcg ccaggttgtg caggtgtttt cgagggatgt gtgcgtgaga atgtatgtgc
    11761 ttcgccacct ccgcctccac tatcccgaca aacccgttaa gacctgtgcg ccacagcaag
    11821 cacaggaggc acatgtgtac cgcgagatac ctgttcaggc aagggaaaag tggacaaaat
    11881 aacctttacg tgatgcggaa ttaaccattc ggcaaggtgg cggatgaatg gctcaaatat
    11941 tgcttccgct cgccgcccgg atctgagggt tgtccggggg ctgctgtcca cgaccgctgt
    12001 ccacgaccgc tgtcacgtca cgggcgagag gggcttggcg ccgtcggggt catcacggcc
    12061 ggcatggtcg gcgtaatcac ggcgccgaac cgtcccaaaa atcttaaccc tgtccaccga
    12121 accgcgcctg cgctgccgca tccggctggt gaggccggag accggcctgc gccacggtgc
    12181 cacgacaccg atcccgacgg gccgaaattc ggcctccggc cagcccggcg tacggccatc
    12241 gatcctggtg cgcgaatcgg ctcgccggcc tggacggtcg ccgcggcggt cgggctcgcg
    12301 gcggtactcc agcggtggga tgtggcgttc accgtcgtac ggtcggccgg tgcggcctac
    12361 ctgctaccgc tggacgcgta ggcgctctgg acccaccagc ggtcgggtgc ggtcgccgag
    12421 tccggggacg ttccctcggc ggcggaggca ccggaccgct ccgccacgcg cctaggcccg
    12481 gtacgcgcct tccggcaagg gctgttgagc tgcctgctca accccgaggt cggcatcctt
    12541 tttgtggcgg tggtaccgca gatcctgccc gaggggtact cggtcccggg gcgacgctgt
    12601 ccctgggggc ggtcgatgca gtcatggcgg cgggccagct gttgctggta gtcgtctgcc
    12661 ccgaccgact cctggagcgg ctgcggggtc cctgcctaca cagcgacctg gagcgtgcga
    12721 cgggagcggt gctcgtcgcg cttgggtggg gacggcgaca gagacagtcg cgggctagct
    12781 ggagcgagga tcccggcgtc cgtcgaggga tccatggccg gagccggacg cgcacggttg
    12841 caacctgcaa tagccacggt cccgtggaag acgtaggcgc gctcggcaaa gcgtgtggcc
    12901 atggcccgaa agcccttgaa agcattgacc gttcactcga cttcgtcgag gcgcctgcac
    12961 atcgtgcgat cgaaggccgc gggcggaccg cccgtactgc ctcggcgttg gtgatcggtc
    13021 caccggtctc cgcgtttcgg ggatggtgtg gtcgatccat ccgcgtcaca ggaacgccga
    13081 ttgcggtggg agccgcacgc cacttcaccg gatgctgcga gttcaccagg accgctcaga
    13141 cgacgacccc ggccgcctgg gccagcaggg agatctcggc cgcgactgcc accgggtcgg
    13201 ccgcgacggt gacctgggcc acgtcgtcca ggcttgggtg tgcgccgacg cgtaccgcac
    13261 gctccgcgtt ccgcaggaga tcgaagtcgt tgatgtcgtt gccgaacgcg acgtactcgc
    13321 ggatctccat cgaggccagg gcctcccact tcgtcgtcga acccggggcg aaatctatga
    13381 tcgcctcgtc gaggtggtgg ttgaccgtca gcccgagcct gcggccggtc tcggcgagtt
    13441 ccgtcatgtc cgacgcgccg acgacgagga acttcaccac ctcgggaagc tcggtgaggt
    13501 ccaccctgcg cgcgaggtcg ccctgatcca cacggctccg gatcgggtga tcgacaggtc
    13561 cggtgtaggc gtagtcccag gggccgtcgg cgaggtaggt cgcctcgtac cgcccggccg
    13621 cctccagcag tgcgcgaagt ccggcaggat cgaatgcggc ccgagcccgc acctgaccgc
    13681 cggccgagac gaggctcccg ttcccgccga tcagggtggc ggacgcgaag gctccgttga
    13741 gcaccggcag aaggtctcgg acggggcggg cggacgcgaa aaccaggtga tggccggcgc
    13801 gttcgcattc gccgagcgcc gcgagaattt cctcgtcgat cgtccgcccg tcgaaacaga
    13861 gcgtgccatc gatatcgaaa accacggtgc gggcgcgaag gctgaacatc accggatgat
    13921 atccggctgt ccggcgatgc cgaggtgatg ccgatgtgat gcccgcaact gtgcccgtgc
    13981 ctccgaccgc ccggccgggc agctcccggg cctggcccgg ggcaccacat cgtgaccggt
    14041 acggcgcggg cgtacggcat gggagtacaa cacgggcgta cggcgcaggc gcagctccat
    14101 ccggcatggg gagggcggca tccttgtgcg gaccgggtga cgtggtccgt cgtacccgca
    14161 ggacaatggt ccacgaggtg agcccggtac cgtaccggcc gggtgagccg cggcagccgg
    14221 ggcgccgatc ccggagccga ccgtacagct gccggcgcca tgggccggcc gtcccgccgg
    14281 tgtaccagga ggcatcagat gaccagtccc gcgatcagcc tgaccaaggt gcaggagagg
    14341 gcccccggcc tggtcagcct ctacaagagt gccgccgtca gtctgcgcaa gcgctccctc
    14401 cagggcgtgc gcgcggccgt ctatctggtg ctcgaccgct ccggctcgat gcgcaactac
    14461 tacaaggacg gcaccgtcca gcacctcgcc gaacaggttc tgggcctgtc ggcgcacctc
    14521 gacgacgacg gcaccgtccc ggtcatcttc ttctccaccg atatagacgg caccgccgag
    14581 ctcgacctcg gcaactatca gggccgcatc gaggaactgc acagtggtct cggccacatg
    14641 ggccgcacga actaccactg ggccatggac gaagtcatcg accactacct ggccagcggc
    14701 tcgtccgccc cggcactggt catcttccag acggacggcg ggcccacgag caagttcgcc
    14761 gcggaacgct atctctgcaa ggcggccacg ctgccgatct tctggcagtt cgtcggcttc
    14821 ggcgaccctg acgagcagga gttcgcgttc ctccacaagc tcgacgacct gcccgttccg
    14881 gccaagcgcg tcgtggacaa cgcgggcttc ttccacgccg gacgtgaccc ccgcagcgtc
    14941 agcgacgacg tcctgtacga cgagctgctg cacgagtttc ccagctggct gaccgccatc
    15001 gacagtgcgg gaagcatgca gtgacgagga gcatgcagtg acgagggatt cggcccctcg
    15061 cgtccgcggc ggtgacggcg cggcggccgg ggccggcccc gcgggtgggc tccgggtcta
    15121 cggggtgtcg gctgccgtgg aaggccaggg gacgggccgg agaggcgatc cgggcgcggg
    15181 gcacggcggg acggtgcccg gatcacccga tgtgcggttg cgtgactacg tgcacggcta
    15241 tgtcggtttc gggcccacga tggggctgcc cgccgtacag cgcgtactgc cggaggtggc
    15301 ggtcatgctg gtgctggact tcgtcgcgcg gccgtcccgc ctggtcacgg cggagggcgg
    15361 ggcggcgcgc atgccgtcgc tgcccgtcat cggcctgcac gaccgccccg ttctggtgga
    15421 gcacggcggc tctccccgcg gtgtggcgat cggcctgaca ccacctggtg ccatgccctg
    15481 ttcggcgtcg cgatgagcga gctggccaac acgtatacga gcctggccga tttagtgggc
    15541 ggccgggcgt ggtgtctggt ggagcagctg tcccagctct cccactggca ggcccgcttc
    15601 acgctgctgg accggacact ggctcagtgg ctggcgggca cgaacgcgcc ggcggccact
    15661 gtgctacggg cctggcgacg gctcacggag tccgccgggc ggctgacgat cgccggactg
    15721 agcgacgaac tgggctgtag ccgccgctac ctggagatgc ggttcggcga acaggtcggc
    15781 ctgccgccca agaccgcggc ccggatcctg cgcttcaaga gtgcggcgcg catactcacc
    15841 gcggccggcg gcggatcctt ctcggagatc gcggggcggt gcggatacag cgatcaggcg
    15901 catctcaacc gcgacttccg ggcgctggcc ggctgcacac cgacggagtt cctgctccgg
    15961 cggtcgagtg gctgacacgg gcacgcaccc ggcccgcctc ggacccgttc gcatttttcc
    16021 aagaggccgc cgcaccctgc ggcataacct cgggagagtg ggcctacggg ggtggtccac
    16081 acacccactc aggaaggccg caccatgggc ggaaccgtcc gcccgccagc tcccggcacc
    16141 gcagcaccgg tgacgggagc cgcagcggtg ccggccatcg ccccgcaggt cagggcgcgg
    16201 ccaaccgggc acatgcccct ctgaggctcc tcggtggcgg tggcggggcg ggccgcgtac
    16261 gggtatcgat gtgccgctca ccggtgccgg gcgggcgcgt ggggccggcc cgcccggcac
    16321 ccggggcggc gtgggagaca gcgctgtgcc tagcgagtga cctgccagct cagcgatgcg
    16381 gagagcggct tgcgcagcgc cgggtcacgg accgcgtccg taccgtcgac ggccttggcc
    16441 gtgaccgtgt gggcgcggcc gtcggaggga acgccgaggg aacgcggtac gaccgtcgtc
    16501 ttgccgcgcc aggctttggc ctcgcggccg tcgacgtacc acttgacctg cgcggaggcg
    16561 ggcagcgtga ccgggatgcg gtctccgcgg gacagtgtgc ggccggcggc gaccgggctg
    16621 ctcagcacgc tcgcatggcg gtagaagccc gcgatcatcg cctcacggcc ggggaggttg
    16681 aactcgcggc cgagggtccg catgatcgag ttctcggtgg ggcggttgag gccgaactgg
    16741 tagtagccgc caccctcgta cgcgccgacc gtgccgccgt ccggcgactt ctggcccatc
    16801 cagcggtacc acttctgctt ccgggtggtc atctggtcga cggtgtaggt ggtgatgttg
    16861 gccgagccgg gctcggggcc ggagtaggtg ccggactggc cgtagtcgta ctcgtcggcg
    16921 agtttgccga gcgagtgacc ggtttcgtga atggctatct gtacggcgtc ggcgttgtgg
    16981 gcggaggcgg tggcgatacc gtcgtaaccg accttcgagc tgatgtcgtt gtagcccgcg
    17041 ccgccgtact tggtggagtt ggcgagcacc acgacgaggt cggcggccgg ggccttggcg
    17101 gcgtacgact cgaccttgcc ggtgtcgacg cagagcaggc gctcgatgtc gtcgcagaag
    17161 aaggcggagc cgagggcggt gtcgcggacc gcgttccggt ccgggtcgcc ggagacgccg
    17221 gactgccggg atacggcatc gacggcccag acgttgaaga ggccggtgta cgaggcgtat
    17281 ggctcgacgg cggtcatctt ggcccatttg gcgcggacat cggcgtggaa ggtcgcctgc
    17341 tgggcggcgg tgtagccgtc gccgatgaag acgacatcga gtttggtgcc gacggggccg
    17401 ttctgcacga tcggcgtgac ctggccgtcg ggggcgggcg cggccttggc ggaccgggag
    17461 agcggcttcg aggccgggat ggtggtgtgc cgggggtggc cgcccggccc ggtgaagtac
    17521 tccacctgct gggtgggttg accctgcggg tccgggggcg gggtggcgcc ctgggcggtg
    17581 ctggtcgcgg cggcggtcag ggcgacggcg gccaggccga cggccgcggc ggtgcgcagg
    17641 gaagtgcgga gggagatgcg tggggtggcg cgtgcggaag tgcgtgtcga ggcgcatatg
    17701 gaggtgcgtc tgagcatggg tgatcctcct ggggcccacc gcaaggcggt gagttgaacg
    17761 ggatgcggcc gcggatcaac gtagaggctg cggtggttcc aggcaacgga tgatgctcaa
    17821 gtgctgtgag ggatcggagg ggcaggggag tggggggtag cgggcaggga gcgcgggcgg
    17881 tggagcgcgc ggcgggcgga tttggtatgg gcgcgctcgg ggtgggcggg ggcggcgggg
    17941 gcaagtcgtc cgcgccgacg gccggttacc tggttctggt accggatggg tccagggcgg
    18001 agcgaccgca agcatctctc cgcgaaggtc attgcaaaga gatgattgct ctcttacgcc
    18061 accgcgcctt ccggaactac tggatcgggc agagcatctc cctggtcgac gaggagatat
    18121 ccagaatcgc ccttccactg gcagctgttc tcatccttga cgcgcaggcc ggcgaaatgg
    18181 gcgggctcac caccaccgct ctggtgccgg ccctgctgtt ctcggtgccg gccggtgcct
    18241 gggtcgatcg ctggcgaagt cggcgccgcg tcatgcccgt caccaacctc ggccgtttcc
    18301 tgctgatggc atcaatcccg gccgcttacg cgtggggtgt gctcgatttc gttcagctct
    18361 gtctcacggc cttcgccatc ggcgcattgg gggtgctctt caacgtctgc gacagcaccc
    18421 tgtatgtatc cctcgtaccg gcgaagagct acttccagag cagctcgttg atgaacggga
    18481 gccgctccct ggccttcacc gccggcccga gcctcggcgg tcttctggtc cagttcgcca
    18541 gagcgccttt cgccctgttc gttgacgcgc tcagctatct gctctccgcg ctctttctct
    18601 tccgtatctc gcccgcggag ccgccgccgt cggcctggcg gagaggtcat ttcaccgcgg
    18661 gcctgaagtg gctcgtccgg gctccgctga tgcggccgat gctcgccgcc gtcgcgaggc
    18721 tcaatttcaa gcgatagctc gcgttgccgg aggtgatgcc caggcgtgcg gcgagccggg
    18781 tggccgtcga cgggccgtag gtgcgcagca gttccaccag ttgaacgcgt acggggtgcg
    18841 cgagggcgcg caggcccttg gcgtccaggg ccacctccgc ttcggggtcc tggcgcttcg
    18901 gtccgcccat gcgatcgctc atgtccggca tggtagaacg cggaagcccg cctgcaaaga
    18961 tttctccgcg ggaagctgct ttcaacggct tgctgcgtaa gcctgttttg gcgtcgggta
    19021 gttatgcgca gtgaggcgga atgccgatcc ctatgcggtt gatgttggac tccttcaatt
    19081 ttcgtcggct tgggttgcct tcgattacct tcggtctacg tgaactgcga tatccctcgc
    19141 cgataattgc cgctgcctcc gccgtaactg tgggcgcgac gaaccccagg tctcgtaccc
    19201 tgacggaaca tcaggcggct gcccatgaat cggcccgacg gccggcagaa ggccgacaat
    19261 tagccggcag ggaagccccg gcggcgcagg catgcccgtg aacgtagctg cgcacgccga
    19321 gcgaggtcaa agccgtctcg gctggtggac ctctgttgcg ggagcggtgg gcggggattg
    19381 cggaaagccg tcggaggggc gaggcatgcg cgtaactcgg gtgcgtcgtc gccgcgttca
    19441 aggaagtcca gataactcgt ggatgtcgca atcgggggga tccacaagga accgcgagta
    19501 agtcggggca ttgcaagtgg aatagctcac accgcatgga ccgtatggtt ttcgggctcg
    19561 tcgttgttca agacatgccc atcagaacgc gtacgccctg cgtcgcgcag ccaacagaaa
    19621 ggcggacctg cggtggagtt tccgcgcgtc gagttcaagg tattgggacc tctggaggca
    19681 gtttccggcg gtcgggtcct cccgctcggc ggaccgaagc agcggacgct gctcgccgca
    19741 ctgctgctcc acgtcaacac cacggtgtcc ggggaccggc tgtgcgatgc ggtctggggc
    19801 acgaccccgc cggcctcggc ccaggccaac gtccgcagct atgccgccgc gttgcgccgg
    19861 gtgctcaacc cggacgcggg agaggaccgg ttgagcctgg ggcacggcgg ctaccaactg
    19921 cgggcgcgac cggacgaagt ggacctgcac cggttcgagg agctggtcga gcgcggccgg
    19981 tccgccctgg ccgggggtgc gcacccggcg gcggccggcc atttccggga ggcgctggac
    20041 ctgtggcgcg gcggtgcctt cgaaggggtg gcgcaccacg acgccctgca catcgaggtc
    20101 gcccgcctcg acgaggcgcg gctcgcggtg ttcgaggact atgccgaggc gcgtctggcg
    20161 ctcggcgaca gccgcgagat ggtgggccca ctgcgggagc aggtggcccg gtacccgctg
    20221 cgcgagtcgc tctggggaaa gctgatgacc gcgcagtacc gctgccaccg cccgggagac
    20281 gcgttgcagt cctacgccct cgcccgtacc gcgctccggg acgagctggg actcgaaccg
    20341 ggcgccgaac tccgccggtt gcaccgcgcg gtcctgggcg gggacccggc cctgctgggc
    20401 gccgccccgg cacctgtcac cgtccccgcg cccgcccccg cgccgcccga ccggcccgcg
    20461 ggaacctggc ggccggtgag ccaactcccc tcggatcccg ccgacttcgt cggccgcgac
    20521 gaggtgctga cccgggccgc cgccttactc cggccggccg ccaccgcgcc gggcgccccg
    20581 ccgcccgtgc ccggatcgcc ctgcgccgta ccggtcgtga tcctcacggg gctccccggc
    20641 gtcggcaaga ccaccctggc cacccggctc gcccacctgc tgcgcaaatc cttccccgac
    20701 ggccagttgt tcctgcacct gggcgg
//
