LOCUS       NZ_NDXL01000001        22565 bp    DNA     linear   CON 27-APR-2024
DEFINITION  Streptomyces kasugaensis strain BCRC 12349 scaffold1, whole genome
            shotgun sequence.
ACCESSION   NZ_NDXL01000001
VERSION     NZ_NDXL01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces kasugaensis
  ORGANISM  Streptomyces kasugaensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 5071473)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Comparative genome analysis for kasugamycin overproduction
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5071473)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Comparative genome analysis for kasugamycin overproduction
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 5071473)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030,
            China
REFERENCE   4  (bases 1 to 5071473)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. May-2015
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 188.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002261115.1-RS_2024_04_27
            Annotation Date                   :: 04/27/2024 02:42:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,951
            CDSs (total)                      :: 7,863
            Genes (coding)                    :: 7,657
            CDSs (with protein)               :: 7,657
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 206
            CDSs (without protein)            :: 206
            Pseudo Genes (ambiguous residues) :: 0 of 206
            Pseudo Genes (frameshifted)       :: 87 of 206
            Pseudo Genes (incomplete)         :: 170 of 206
            Pseudo Genes (internal stop)      :: 23 of 206
            Pseudo Genes (multiple problems)  :: 65 of 206
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:37:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3944306
            Orig. end                         :: 3966871
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NDXL01000001.1.
            Bacteria and source DNA available from BCRC.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22565
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="24"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22565
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22565
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12565](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12565)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            213..617
                     /locus_tag="B7024_RS17045"
     CDS             213..617
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014043550.1"
                     /locus_tag="B7024_RS17045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_094792451.1"
                     /transl_table=11
                     /translation="MMPWNLLDLDSALRASWAADTCSPDDLARADWQPENPAWGHCDIT
                     ALIVNDVFGGGLIAGEVHFNEVQHGFHMWNRLPSGIEIDLTREQFRRGQTVTEGRVVER
                     PPGPLRRWDEYLLLRKRVIVHLGYLPEPAV"
     gene            complement(689..1129)
                     /locus_tag="B7024_RS17050"
     CDS             complement(689..1129)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS17050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_131122210.1"
                     /transl_table=11
                     /translation="MTKVRDRGEVLGFGVPAVLFLGVAYLGITNGYQFIANDFFALMYC
                     LASIGFASVPLLAWRRGGGRYADPGFVRSAWFPWLFTTMQGVAYSSPRSDANFFMLIFG
                     WGMFIYAGMVALYFLARALWAVDNDQAVPATGEDAVRPEASA"
     gene            complement(1300..1500)
                     /locus_tag="B7024_RS17055"
     CDS             complement(1300..1500)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS17055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_131122209.1"
                     /transl_table=11
                     /translation="MSIPTRALAYFDDEPTFVHAARTLGIQAHLFTEPAEFTAHLRALG
                     LPLTSRDRQEVPAPAFDARER"
     gene            complement(1589..2809)
                     /locus_tag="B7024_RS17060"
     CDS             complement(1589..2809)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004949004.1"
                     /locus_tag="B7024_RS17060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_094792454.1"
                     /transl_table=11
                     /translation="MEMEPDVWAHPDLRAAVAVEDWPALLKGWRNLTRSSQSKLGALVG
                     LAQPDISAIENRRREVTSVEVRQRIIEGLGVPAELLGGAGIKMPLPSLVLPGLVADPET
                     DRLRRVGEGGTRLDVASLEAMERLLAAHRRAEDTLGSRVMNGVVATQFAAVAGHYDQAR
                     GPLADRLVKLMAEYAQFLAWMAQDQDNAPVALGWFDRSYDWALESGYGDMAATTMSMKA
                     HLAWSNGNGRRCIRLGEAAASTAGVSEATRAMAVQMAGRGHALEGHADDAYRRLEEAQG
                     IITDASDAPPWLYFYGESWFAAQRGMADLHLKSWGSAIDKLMAGLAGFAPDFRRDRAWY
                     GSCLAHAYAGAGETEAAFSTALGIINDASEIGRPHAWGELHTVAALLLRRGAQEGRELV
                     DALADLD"
     misc_feature    complement(2426..2428)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(2812..2821)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     gene            3343..4539
                     /locus_tag="B7024_RS17065"
     CDS             3343..4539
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013775.4"
                     /locus_tag="B7024_RS17065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphotransferase"
                     /protein_id="WP_172450745.1"
                     /sec_met_domain="APH (E-value: 1.4e-09, bitscore: 36.2,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDIPHDSSTACPTTGDVFGYASEQIHRAAAEMWPRVPVLLGNHI
                     PSVTGYVHQLQVGDRPMYAKHSMLGGSLVSVLTGEYGTWEAVAKRQAAYVDAPDSLLAR
                     EAKQLAFLASDGKPRACAVIGLRRGVLFTEPVPGPALSALMLTSPAEAGHLLVRAWSEL
                     VPLHSRNFPGEEIAERSIAGTFRRKFNGLSGETYLGRLGVARLSEETSAEVIALIRPLV
                     LRLHRVPLGPTAAEDKVLVYGDLKPEHIVFPDGPDKAPYFIDPGLMRAAPSVDAAKLIS
                     RTTLSLAASGASAAAAKDIALGIQEFVRTLLGNADHLRRDAMLRRLLVLWCMDTINIMT
                     TYLSAPSAVPLPVQGRRLAEDPLPVLRLVNAASDLLTTRSESTAAWERALDGVSGVGA"
     misc_feature    3367..3382
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.95"
                     /tool="antismash"
     gene            4536..5429
                     /locus_tag="B7024_RS17070"
     CDS             4536..5429
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981775.1"
                     /locus_tag="B7024_RS17070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_094792456.1"
                     /transl_table=11
                     /translation="MTTLGIVGAGAVGQTLATAMVSAGLAQRLLVTSRTQSQAQALADD
                     LADLAASTSSPTTVTAAALPDLLDCQAVVIAVRARFTNTASRNVRMGGAAANAPVVRIL
                     AAALRGHSGTVIMVTNPVDLLSRLFAEFSGCTRVFGIGSNLDTARYRLTLARLLNVPKE
                     AVQGHVIGEHGDGAVICASTTTVNGHPVHVPLKAVREELTARPGRISSGIGRTRSGPAG
                     AVLSTLRLALGHHDGTTELTTPHNGGWYGIPLRFTAGQPVPCLPTLDSTETQLLHTART
                     KLHTAYTELVHPEGTS"
     gene            5426..6556
                     /locus_tag="B7024_RS17075"
     CDS             5426..6556
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981774.1"
                     /locus_tag="B7024_RS17075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_342352222.1"
                     /transl_table=11
                     /translation="MTATAIRIQAADSAVPVLSSTPSITQWSGRYFGHWWNATATEATE
                     ICTGPVVLADVDPDRYAALGRQVTDTRHEQIVYARVPLLVAEDRNGTIRAFSPRDQLAY
                     ISEPHTGRLTIVGTDAEAVAAATARLAREVVRGLLLRDGWTLLHASAAVIDGNAILSFG
                     SKGAGKTTTALLLACKSGAELLANDRIFVRRDDAGTVQVLPWPSAAALGLGLLDALGMY
                     DVVRERVQAGERLHPTQDRRVTEALLEGRREPLWAPNGKEMKVQLHPDQFPDWFGIRLA
                     SSARAAMLLFPSVFPDVEPRTADEVRGLTESDFMTGATEDRYPDVFRLIRVNGGGRPQD
                     REHVAAHLSRLPHHGIVLGHDIDAAGEFLTKITTSA"
     gene            7276..7581
                     /locus_tag="B7024_RS17080"
     CDS             7276..7581
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552065.1"
                     /locus_tag="B7024_RS17080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PAAR domain-containing protein"
                     /protein_id="WP_094792458.1"
                     /transl_table=11
                     /translation="MPPAARVGDMHTCPMQTPAVPTPIPHVGGPILPTGKVNVLIGNLP
                     AAVVGNQCVCAAPAPDAILAGSATVLIGGLPAARQGDATTHGGTITIGLPTVMIGG"
     gene            complement(7858..9618)
                     /locus_tag="B7024_RS17085"
     CDS             complement(7858..9618)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735510.1"
                     /locus_tag="B7024_RS17085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_094792459.1"
                     /transl_table=11
                     /translation="MADQPPRTAHRAPGRVQLRRELTTEPGRLLCALLLALVSTAAALA
                     VPLLVQKIITDFSAHRLLGPDVLMMCAATIGSALTQALSGFLLARIGERMTYRLRTRIM
                     DHTLRLPLSVARAQGTGELTARITSDALLLRQAVEVVTQLPLAALTVAATLLVMVWIDW
                     VLTLVTVVAFAVLTVLVLLVVRRMKANVNGQQDAVGYISQRFTANLEALTTIKAYRAEP
                     MAARTLAAAAERLRAVSLEGARLNALIPPAVSLGNQFAMIAVILTGGARLAAGSLDVAA
                     FAAFLLYLLQTVPSIGALATGFSRLQASLAARDRCSELLSLAPESDPRDTPRTAPTPRP
                     QAPSVVFRKVSYTHTGSDDPALRGISFTAARTGLTAVVGPSGAGKSTALSLIDRFIRPT
                     SGSITVLGHDTRHWPLDELRARIAYVDQAFTLLEATARENLQLGRERHAGADELAAALD
                     AVGLTDDITRLPQGLDTPLGRESDLSGGQRQRMALARALLSDADIVLLDEPTSQLDGIN
                     EHRFRAIMEDLAATRAVIVVAHRLSTVQHARHVIMMNRGTVLDAGDHPTLLQRCTPYRD
                     LVTSQTIPPP"
     gene            complement(9782..9919)
                     /locus_tag="B7024_RS17090"
     CDS             complement(9782..9919)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998309.1"
                     /locus_tag="B7024_RS17090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_094792460.1"
                     /transl_table=11
                     /translation="MAILDLQTMEPPESEAAPIDDVLATGSSLSVLNCTVSTVSTLLCL
                     "
     CDS_motif       complement(9866..9919)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAILDLQTMEPPESEAAP"
                     /locus_tag="B7024_RS17090_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9782..9865)
                     /prepeptide="core"
                     /locus_tag="B7024_RS17090_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="12.20"
                     /molecular_weight="2563.0"
                     /monoisotopic_mass="2561.4"
                     /core_sequence="IDDVLATGSSLSVLNCTVSTVSTLLCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAILDLQTMEPPESEAAP"
                     /leader_location="[9865:9919](-)"
                     /alternative_weights="2581.0"
                     /alternative_weights="2599.0"
                     /alternative_weights="2617.0"
                     /alternative_weights="2635.0"
                     /alternative_weights="2653.1"
                     /alternative_weights="2671.1"
                     /alternative_weights="2689.1"
     misc_feature    complement(9912..9926)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            complement(10001..12565)
                     /gene="lanKC"
                     /locus_tag="B7024_RS17095"
     CDS             complement(10001..12565)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998308.1"
                     /locus_tag="B7024_RS17095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_094792461.1"
                     /sec_met_domain="micKC (E-value: 0.0, bitscore: 1068.1,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 3e-08, bitscore: 31.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 1.4e-06, bitscore: 26.4,
                     seeds: 156, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.4e-08, bitscore:
                     29.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNRYEAYAYADPLFYDSPRRWGAHEEFAAVEWPLPAGWERVDQE
                     IWAVVRPVDVQLPAQGWKIHVSSEAGDAEEVLEAVHAYCLRERVTFKFLRGLPILQVQN
                     SKYAPRESSGKFCTLYPVDQAELERCLDGLGRVLAGRKGPYILSDLRWGEGPLYLRYGG
                     FAERYCRNDAGARVLALIGPEGRLVPDVRGTGFAVPDWAPVPDFIAAAVAERAASRDTG
                     LPYTVERVLHFSNAGGVYLAHDGDGGPRLVLKEARPFAGLDQRGVDAVTRLRNEHDILV
                     RLAGVPGVPAQHGLLTAWEHEFLVQEFVEGRLLSEWLATRYPLIHPDADEAAVAEYTRE
                     ALGIVDRIEEVLAAIHARGVVFGDLHPRNLIIRANGDICFIDFELASTVEDFVRPALGA
                     AGFAAPPGCTGTRIDRYGLAAIRLWLFLPLAQLPALDPGKADELADAIELRFPVPDGYT
                     DEIRRLLGPAPSDGRSRRPELGHDREQLNTLLAAPTADWPRIRDSLAAGITAMATPDRT
                     DRLFPGDVAQFTHGGLGLAYGAAGVLYALHSTGATIAPDHVRWLVRASRTRPVEPGLYF
                     GGHGVAYVLDLLGERDAALALLRRLATAPDEEPQPGLAAGAPGIALTLLHFAAATGEHR
                     LLEQALVLARSCADALEKAGRSDPRRTAGLLAGASGTALALVRLYEHTGEHALLDQAQT
                     LVELDLDRCTSLADGTFQVADGRRVLPYVETGSAGIGLALNTLLAHRPDAPSACHEQAI
                     RRAAEPEFVIQPGLFNGRAGLLGYLALTRHRAPDPAGTALLDRQRALLALHQVSYQGLL
                     AFPGDQLLRLSADLATGSAGVLLALGTALADTPFLPWTGTPG"
     misc_feature    complement(11627..11629)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12767..12783)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.4"
                     /tool="antismash"
     gene            12848..13012
                     /locus_tag="B7024_RS41420"
     CDS             12848..13012
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS41420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_172450747.1"
                     /transl_table=11
                     /translation="MGIEFLDRPGGACCEKRDVKAAKGFMAKLMKEQQHVPRVLVTDKA
                     NVRRRFRAR"
     misc_feature    complement(12854..12868)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.07"
                     /tool="antismash"
     gene            13177..14109
                     /locus_tag="B7024_RS42505"
     CDS             13177..14109
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571575.1"
                     /locus_tag="B7024_RS42505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="site-specific integrase"
                     /protein_id="WP_244933969.1"
                     /transl_table=11
                     /translation="MTLVTPEQRRSTIALMPSAPARRTAHRTTAAAWAAPSARAAGDDR
                     VAPGDGAGILTCTPPRTASHTCALDRSSRSSGSTWLASSAQRLAQLVAAGRAGWAPRVI
                     RSCRHRSANKDSTARSRASSAARSAAASAIARFGYRCWEDVELGNATIVIANTRTMMGN
                     RYVVEKDTKSLAGERDLPLPAPVLAALKAFRALQTEEKLALGEAYVASGHVLVHEAGDA
                     FTVKQPRRRAYRLMELLGLRRVRLYDARSSCFTFLADNGVPDRILARWAGHTKVKTTKR
                     WYVKPDVTDLRGATTTWDGLHGVAVEGQA"
     gene            14204..15493
                     /locus_tag="B7024_RS17105"
     CDS             14204..15493
                     /NRPS_PKS="Domain: Abhydrolase_1 (19-130). E-value:
                     2.7e-22. Score: 71.5. Matches aSDomain:
                     nrpspksdomains_B7024_RS17105_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982632.1"
                     /locus_tag="B7024_RS17105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_094792462.1"
                     /sec_met_domain="PF00561 (E-value: 9.5e-18, bitscore: 62.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2e-14, bitscore:
                     52.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSETPANTLQYRLDGPEDAPVLILGAALGTTWHMWDRQIPELTRH
                     WRVLRFDLPGHGGSPAHPAASVAELADRLIATLDALGVDRFGYGGCSIGGAIGVQLALT
                     RPHRLTSLALVSSSPRHGTADAWRQRGVVIRTNGLDPIARTAPERWFTPGFAEAQPAIV
                     EWAVQMVRTTDPGCYIAACEAMASFDVRSALGRVGVPTLVVVGSADRTTPTADARTLVA
                     GIPDASLALVPGTSHLAPVEQPAAVTDLLIRHFTTAWQDRPGGGPAAPGATANTPVLAP
                     PRPPQPVPAAIESGLAQPARLRGSTYEQGVKIRREVLGDAHVDRAEAATDGFTDDFQDF
                     VIRYGWGETWSRPGLDRRTRSIVTLTALVAGGHHDALASHTRAALRNGLTPVEIKEILL
                     HTAVYCGVPAAHAAFAVAQRVIREETTPEG"
     aSDomain        14261..14593
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B7024_RS17105_Abhydrolase_1.1"
                     /evalue="2.70E-22"
                     /label="B7024_RS17105_Abhydrolase_1.1"
                     /locus_tag="B7024_RS17105"
                     /protein_end="130"
                     /protein_start="19"
                     /score="71.5"
                     /tool="antismash"
                     /translation="PVLILGAALGTTWHMWDRQIPELTRHWRVLRFDLPGHGGSPAHPA
                     ASVAELADRLIATLDALGVDRFGYGGCSIGGAIGVQLALTRPHRLTSLALVSSSPRHGT
                     ADAWRQR"
     gene            15583..16221
                     /locus_tag="B7024_RS17110"
     CDS             15583..16221
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575137.1"
                     /locus_tag="B7024_RS17110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_094792463.1"
                     /transl_table=11
                     /translation="MELTKKTHACVRLEKDGQTLVIDPGVFSETDAAVGADAILVTHEH
                     PDHFHEDRLRAGMAANPGAEIWTLASVAEQLAAAFPGRVHTVGEGDTFTAAGFDVEVHG
                     QLHAVIHPDLPRITNVGFLLDGSVFHPGDALTVPQGRRVDTLLLPVHAPWNKVAEIIDY
                     VREVAPRRAIDIHDSLLQDHARPIYDGLIGGLGGADHGRLAPGAHTDVG"
     gene            16251..17030
                     /locus_tag="B7024_RS17115"
     CDS             16251..17030
                     /EC_number="3.1.11.2"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563016.1"
                     /locus_tag="B7024_RS17115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exodeoxyribonuclease III"
                     /protein_id="WP_094792464.1"
                     /transl_table=11
                     /translation="MRIATWNVNSITARLPRLLAWLESTGTDVLCIQETKCAADQFPVG
                     QLRELGYEAAVNATGRWNGVAVLSKVGLADVVTGLPGGPEYDGVQEPRAVSATCGPARI
                     WSVYVPNGREVGHEHFSYKLRWFEALTAAVAEDAAAGRPFAVLGDFNVAPTDEDVWDPA
                     VFEGLTHVTPAERDALATLRGTGLTDVLPRPLKYDRPYTYWDYRQLGFPKNRGMRIDLV
                     YGNAPFAEAVSDAYVDREERKGKGASDHAPVVVDLDV"
     gene            17211..17651
                     /locus_tag="B7024_RS17120"
     CDS             17211..17651
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602204.1"
                     /locus_tag="B7024_RS17120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6278 family protein"
                     /protein_id="WP_052858061.1"
                     /transl_table=11
                     /translation="MNMSFLDKWRRHPDADRRLSLAESVRADPGSVVELLSECELLRAQ
                     AADSGVELDDSVRSLEELDQLQPVWRDDPEVLPWLGNDAGLYLGTVLVRTVRGAVWQVR
                     QDGRPVVRLASGREIDVVAAGQDWADVGAPELSQEYAEVAES"
     misc_feature    complement(17212..17226)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.17"
                     /tool="antismash"
     gene            17877..18620
                     /locus_tag="B7024_RS17125"
     CDS             17877..18620
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037329.1"
                     /locus_tag="B7024_RS17125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_094792465.1"
                     /transl_table=11
                     /translation="MAGEALIELRGVNKYYGKLHVLQDIDLTVGRGEVVVIIGPSGSGK
                     STLCRTINRLETIESGTIMLDGTPLPDEGRALAELRAEVGMVFQSFNLFAHKTVLANVM
                     LAPVKVRKVKKEDAARRARELLDRVGLASQAEKYPAQLSGGQQQRVAIARALAMDPLAL
                     LFDEPTSALDPEMINEVLEVMQQLARDGMTMVVVTHEMGFARSAANRVVFMADGRIIED
                     RAPEDFFTAPRSDRAKDFLSKILKH"
     gene            18634..19566
                     /locus_tag="B7024_RS17130"
     CDS             18634..19566
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602202.1"
                     /locus_tag="B7024_RS17130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glutamate ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_094792466.1"
                     /transl_table=11
                     /translation="MPHSRTPRLRRALLAAALTLLALATAAGCGRNGSPPVKSPKAGEL
                     PHYPVAENFRLPDSPTWRRAEARGHLVVGAKEDQPYLGERDPATGTYSGFDIEIAKMMS
                     AALGFDPATTRFKTIASANRETALQNGQIDFYVGTYTINALRKKQVGFAGPYYLAGQGL
                     LVRTDEKDIHGPQDLAGKRVCSAAGSTPAQRIAADYPQAILVTYDTYSVCVDNLLTYQV
                     DAVTTDDAILLGYAAKAPDELKVVGKPFSEEPYGIGVPREDTALRAALNDALVAAERDG
                     YWKRAYEATLGLSGVPAPQPPPVDRYPAG"
     gene            19584..20228
                     /locus_tag="B7024_RS17135"
     CDS             19584..20228
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019764397.1"
                     /locus_tag="B7024_RS17135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_052858071.1"
                     /transl_table=11
                     /translation="MNVLLDNLSLYGEGLLGTVELTVYASLLALFLGFLTAACRVAPVR
                     SLRAFGTVWVTVLRNTPLTLLFFAVLLGLPRFGLVLPFQMFAVLALGCYTSAFICEAVR
                     SGINTVPVGQGEAARSLGMTFPQTLGDVVLPQAFRTVIPPIGSTLIALAKNSAIAGSFS
                     VVELLGTYRTLSELGYSIIWTFIWIAVGYLIVTLSISALFHVLEKRWGVAR"
     gene            20225..21076
                     /locus_tag="B7024_RS17140"
     CDS             20225..21076
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602200.1"
                     /locus_tag="B7024_RS17140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_052858074.1"
                     /transl_table=11
                     /translation="MTTALYDVPGPKSKRRHLLYGAGSTVVLLGLLGWLVYLLFHTGQF
                     TAQKWTPFLYKGIQELLLRGLGNTLRAFGYAAVFSLALGAVLATGRLSVHRPVRWVSTA
                     LVEFFRAMPVLVMIFFIYVALKAEPLTALVAGLTLYNGSVLAEVFRTGIHAVERGQGEA
                     AYALGMHKTQVMTHVLVPQAVRAMLPTIISQLVVALKDTSLGYLITYEEFLHAGKLIAA
                     NLDYGLPFIPVVMIISPIYIGMCMLLSWCAHWVARRQRRNPKVEAVEVGAAEPGTLLPG
                     GP"
     gene            complement(21146..21595)
                     /locus_tag="B7024_RS17145"
     CDS             complement(21146..21595)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240450.1"
                     /locus_tag="B7024_RS17145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_094793236.1"
                     /transl_table=11
                     /translation="MGHPHLPTTEAAVTAIREIAGEYHLELTVTDDIGADQTSRRTSSG
                     AFTVLDADGSLPHEAFVELGGSPAVSVQIFPEEDARITVDSVTFPDVPRDSVPAFLRSV
                     YGGLAHVKGRTFPPGQWLVVPLPGDETYKELIFRGLSPWMARTFR"
     misc_feature    22047..22061
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 20.73"
                     /tool="antismash"
ORIGIN
        1 atcgcccgcc gccctgcgca gggcccgcgc ggagaaggcc ggtgtgcacg gacagtggtc
       61 cgtccgggtg agcggatttt tcaggtccct gtgggcggac agttgatctc cctgtccggc
      121 attattttcc gtccctcgga tgggggttgg gttgggggcc ctcggcttcc gcgggcagcc
      181 tcggtgccag tggtgactgc gatgctgccg acatgatgcc ttggaacctg ctcgaccttg
      241 acagtgcctt gcgcgccagc tgggccgctg acacctgttc cccggacgac ctcgctcgcg
      301 ctgactggca gccagagaac ccggcctggg gtcactgtga catcacagct ttgatcgtta
      361 atgacgtttt cggtggcggc ctcattgccg gtgaggtgca cttcaacgag gtccagcacg
      421 gcttccacat gtggaaccgg ctgcccagtg gcatagagat cgacctgaca cgcgagcagt
      481 tccggcgggg ccagaccgtc accgagggcc gtgtggttga acgcccaccg ggccctttgc
      541 gtcgttggga cgagtacctg cttcttcgca agcgggtcat cgtgcacctc ggttatctgc
      601 cggagccggc tgtttgagct ggccgggatc agcttggccg gttcacggga cgacgccctg
      661 gccggtgggc ggcgtgaccg gcggcgggtc aggcgctggc ctccggccgc acggcgtcct
      721 cgccggtggc gggcacggcc tggtcgttgt cgacagccca gagcgcgcgg gcgaggaagt
      781 acagggcgac catcccggcg tagatgaaca tgccccagcc gaagatcagc atgaagaaat
      841 tcgcgtcgct gcgcggggag ctgtaggcga cgccctgcat ggttgtgaac agccacggga
      901 accacgccga ccgtacgaag cccgggtccg cgtaccggcc gccgccccgg cgccacgcca
      961 gcagcgggac cgaagcgaag ccgatgctgg ccaggcagta catgagggcg aagaagtcgt
     1021 tggcgatgaa ctggtagccg ttggtgatcc cgaggtaggc gaccccgagg aagagcacgg
     1081 ccggcacccc gaagcccagc acctcgccac gatctcggac cttcgtcacg ctttcccctg
     1141 ctgtcgacgt ctcattcggc accgtaccgg cccgcgtaca gccggatccg ccgatcggca
     1201 ggaaggggcc aggaggccgg ggccggctat tcgcggcgcg cgagcccctc ggggtgggct
     1261 gctgccgggg ctgaggggcg aaccatcttg gcggggacct caccgctccc gggcatcaaa
     1321 ggcgggggcc ggtacttctt gacggtcccg gctggtcagg ggaagaccga gtgcgcgcag
     1381 gtgggcggtg aactcggctg gctcagtgaa caggtgggcc tgtattccga gggttcgggc
     1441 ggcgtggacg aaggtgggtt cgtcgtcgaa gtaggccagg gcgcgggtgg ggatgctcat
     1501 gcgttcggca gcgtggcggt agacgtgggg tgagagtttg tcgatgccaa gcaccacgtg
     1561 aggcccacga ggccccgagg tctctgggtc agtccaggtc tgccagcgcg tccacgagtt
     1621 cccgcccctc ctgggcgcct cgccggagta gtagggcagc taccgtgtgc agctcgcccc
     1681 aggcgtgggg ccggccgatc tctgacgcat cgttgatgat gcccagcgcg gtggaaaagg
     1741 cggcctcagt ctctcccgcg cctgcgtatg catgtgcgag gcacgatccg taccaggccc
     1801 ggtctcggcg gaagtccgga gcgaagcccg ccagtccagc catcagcttg tcgatggcgc
     1861 tgccccagct cttcaggtgg aggtccgcca tgccgcgctg cgccgcgaac caggactctc
     1921 cgtagaagta cagccaaggc ggagcgtcac tggcgtcggt gatgatcccc tgggcctctt
     1981 ccaggcgtcg gtacgcgtcg tcggcatgtc cttcgagggc gtgcccacgc ccggccatct
     2041 gtaccgccat ggctcgggtt gcctcgctta cccccgcggt agaggccgct gcctctccga
     2101 ggcgaatgca gcgccgaccg ttcccgttcg accaggccag gtgagccttc atgctcatgg
     2161 tggtggcggc catgtcaccg tacccagact ccagtgccca gtcgtaggag cggtcgaacc
     2221 acccaagcgc cacaggggcg ttgtcctggt cttgtgccat ccacgcgagg aactgggcgt
     2281 actccgccat cagtttgacc agccgatccg caagcggccc tcgggcctgg tcatagtggc
     2341 cggccaccgc cgcgaactgc gtggcaacga ctccgttcat caccctcgaa cccagggtgt
     2401 cttcagcccg acggtgtgcc gccagtaaac gttccatcgc ctccagcgag gcgacgtcca
     2461 gccgcgtgcc gccttcgccc acccgccgca gccgatccgt ctccgggtct gccaccagac
     2521 cgggcagcac tagggagggc aagggcattt tgattccggc accgccaagc aattcggcgg
     2581 gaacgccgag cccttcgatg atgcgctgcc gcacttcaac cgaggtgact tctcggcgcc
     2641 ggttctcgat ggcggagatg tccggctgtg ccagcccgac aagcgcgccg agtttgctct
     2701 gactgctgcg agtcagattt cgccagccct tcagcagcgc cggccagtct tcgaccgcca
     2761 ccgcagcccg caggtcaggg tgtgcccaca cgtccggctc catctccatc ctcaaaatat
     2821 agggcggccc tatatgtcgc ggcagtggat cgatacagcc aacagccgac atggtgaagc
     2881 cgcacccccg ggacgacaac gattccgggg ccctgctccc cctcgcagcg ggccatgggc
     2941 ccaatccccg ccgatccgcg gcccgctgca tcccccgctg gagaggagca agaacggtga
     3001 ccaacgatgt gtacgtcaga gaggtcgggg accaccgcct gcttggacgt gaggtcgcgc
     3061 agttgcagtc cggacgtcgc ggaacggtcg gtctgatcct ggaataccgc accaaggcaa
     3121 ccgggaagct gatccggagt gtggcgcaca tgcggccgct cgacggctcc ggcagggagt
     3181 ggacctcgga cccggcggac ctccagccca ttcggcccac cgctccggat atcccggagc
     3241 gagcacgatg tgctgatgcg ggggccctcg ccacgcgtgg cgctgtcaac cccggcctgc
     3301 ccgcgtcaat tccgacagcc ggacatcaac gtggaggcgc acatgcgtga cattccgcat
     3361 gactcttcga ccgcctgtcc cacgaccggc gatgtcttcg gctacgccag cgagcagatt
     3421 caccgggcgg cggccgagat gtggccacgc gtacctgtcc tcctcggcaa tcacatcccg
     3481 agcgtcaccg gctacgtgca ccagcttcag gtcggagacc gaccgatgta cgccaagcac
     3541 tccatgcttg gtggctccct cgtctccgtc ctgaccgggg agtacgggac ctgggaggcg
     3601 gtcgccaagc gccaggcggc gtacgtcgac gccccggatt ctctcctggc gcgagaggcg
     3661 aaacagctcg ccttcctcgc gtcggatggc aagccccggg cgtgcgctgt catcggactg
     3721 cggcgcgggg tgctgttcac cgagcccgtc ccggggccgg ctctctccgc cctcatgctc
     3781 acttcaccgg ccgaggcggg tcatcttctg gtcagggcgt ggtctgaact ggtgcccctg
     3841 cacagtcgga actttccggg cgaagagatc gctgaacgct cgattgccgg gaccttccgt
     3901 aggaagttca acggcctgag tggggagacc tacctcggtc gtctcggagt ggcccggctt
     3961 tccgaggaaa cctccgctga ggtgatcgcc ctcatacgcc cgctcgtcct gcggctgcat
     4021 cgggtgccgc tcggccctac ggctgccgaa gacaaggttc tggtgtacgg ggacttgaag
     4081 ccggagcaca tcgtgttccc ggatggaccg gacaaggcgc cgtacttcat cgaccccggc
     4141 ctgatgcggg ccgctccctc cgtggacgca gcaaagctga tcagtcgtac cacgctgtcc
     4201 ctcgccgcct cgggcgcctc tgccgcggct gcgaaggaca tcgcgctcgg cattcaggaa
     4261 tttgtccgta ccctcctcgg caacgctgac catctgcgcc gggacgcaat gctgcgcagg
     4321 ctgctggtgc tgtggtgcat ggacacgatc aacatcatga ccacctacct gtccgctcct
     4381 tcggcggtgc cgctccctgt gcaggggcgt aggttggccg aggatccgct gccggtcctg
     4441 cgcctcgtca acgcggccag cgatctcctc acgacccgat cggaatccac ggccgcgtgg
     4501 gagcgtgccc tcgatggcgt cagcggggtg ggggcgtgac caccctcggc attgtcggcg
     4561 cgggcgctgt cggccagacc ctcgctaccg ccatggtctc tgccggcctc gcgcaacgac
     4621 tgctcgtcac ctcccgtacc cagtcacaag cgcaagccct cgctgacgac cttgccgacc
     4681 tcgctgccag cacaagctcg cccaccacgg tcacggcagc ggcgctccct gatcttctcg
     4741 actgtcaggc tgtggtcatc gccgtccggg cccgcttcac caacaccgcg agcaggaacg
     4801 tgcgcatggg cggagccgcc gccaacgccc ccgtggtacg gatcttggcc gctgccctgc
     4861 gcgggcacag cggaacagtg atcatggtga ccaaccctgt cgaccttctg agcagactgt
     4921 tcgccgagtt ctccggctgc acgcgcgtgt tcggcatcgg ctcgaacctc gacacggccc
     4981 gctaccgcct caccctcgcc cgccttctga acgtgccgaa ggaggccgtg cagggacacg
     5041 tcatcggcga acacggtgac ggcgcggtga tctgcgcgtc caccaccacc gtcaacggtc
     5101 atcccgtcca cgtaccactg aaggccgtac gtgaagaact caccgcccgg cccggccgca
     5161 tctcctccgg aatcggccga accaggagtg gacccgccgg agccgtgctg tccaccctcc
     5221 gcctcgccct gggccaccac gacggcacca ccgaactcac cactccgcac aacggtggct
     5281 ggtacggaat tcccttgcgg ttcaccgccg gccagcccgt gccctgcctg cccaccctcg
     5341 actccaccga gacccagctg ctccacacgg ctcgcaccaa gctccacacc gcatacaccg
     5401 aactcgtcca ccccgaaggg acatcgtgac cgccaccgca atccgcattc aggccgctga
     5461 ctcggccgtg cccgtcctca gcagcacccc ctccatcacg cagtggtccg gccgctactt
     5521 cgggcactgg tggaacgcga ccgccacaga agccaccgag atctgcaccg gccctgttgt
     5581 gctggccgac gtcgaccccg acaggtacgc cgcgctcgga cgacaggtca ccgacacccg
     5641 gcacgagcag atcgtctacg ccagggtgcc cctcctcgtc gccgaggacc gcaacggcac
     5701 gattcgggcc ttctcccccc gcgaccaact cgcctacatc tcggagcctc acaccggccg
     5761 cctgaccatc gtcggcaccg acgccgaggc cgtcgccgcc gccaccgccc gcctggcccg
     5821 ggaagtcgtc cgcggcctcc tcctgcgcga cggctggaca ctgctgcacg cctcggccgc
     5881 cgtgatcgac gggaacgcca tcctctcctt cggctccaag ggcgcgggaa aaacgaccac
     5941 ggcgctgctc ctcgcctgca agagcggcgc tgagctactc gccaacgacc gaatcttcgt
     6001 ccgccgcgac gacgcaggaa ccgtgcaggt gctgccgtgg ccctcggctg ccgcgctcgg
     6061 gctcgggctg ctggacgctc tcggcatgta cgacgtggtc cgtgaacgcg tacaggccgg
     6121 cgaacggctt caccccaccc aggaccggcg agttaccgaa gccctgctcg aaggccggcg
     6181 tgagccgcta tgggccccca acggcaagga aatgaaggtc cagctccacc ccgaccagtt
     6241 ccccgactgg ttcggcatcc gcctggcctc cagcgccagg gccgcgatgc ttctgtttcc
     6301 ctcggtcttc cccgacgttg aaccccggac tgccgacgag gtacgcggtc tgaccgagtc
     6361 cgacttcatg accggcgcga ccgaggaccg gtaccccgac gtcttccgcc tcatccgggt
     6421 caacggaggc ggccggccac aggatcgtga gcacgtcgcc gcccacctct ccaggcttcc
     6481 ccaccacggc atcgtcctcg gccacgacat cgacgccgcc ggtgagttcc tcaccaagat
     6541 caccacgtct gcctgaccca gctcccgccc gaccttccaa gacagtgggc acgggcggat
     6601 caggaaccgg ggatcacgcc ggtacgaggt ccggcgccat cccagcaacc gcaagggaaa
     6661 cagtgagaga cgaccgccgc tcataccagg taccccggcc cacctccgca ccacccaaga
     6721 tcgagcggaa ccagagacac aggccatgca tcctgagcag gcgcgctgcc caatcggctg
     6781 gcggtcgtcc ctcggagcga ccgagaatcg caacaacacc ccgacctgac tcgcggccag
     6841 atgagccgca tcctgaccga ccagggccac taccgccgcg cgctcaccct cgccgacggc
     6901 gcccttcacc tcggcgccac caaggccacc ccgccgtacg gtcctggttg cacgccgtgc
     6961 acacccacca ccacgcctgc ctcggcaacg cccgcggcgc ccagagtgac ctctgtgccg
     7021 cctggaacct gggaccggcc acgccgtggt ccgcctcggc cccaacaccc cggctctcct
     7081 cagcgcgggc cagaaggccc tcgacgaagc ccgcgccgcc gggcccggcg ggaaccggcc
     7141 ttcgtcggcc ttcaccaccg cgatccccgg tcgtcaacct tcgatgacaa tcggtcctct
     7201 cccgcccgtt ggtctcccgc gtgatgcgcc gaacggtcgc gctgaagaag cccacccccg
     7261 gagaggagcc gtcccgtgcc tccagcagca cgggtaggtg acatgcacac ctgccccatg
     7321 cagacccccg ccgtaccgac ccccataccc cacgtcggtg gtcccatcct gccgacgggc
     7381 aaggtgaacg tactcatcgg caacctgccc gccgccgtag tgggcaacca gtgcgtctgt
     7441 gccgccccgg cgccggacgc gatcctcgcc ggcagcgcga cggtactgat cggcggcctc
     7501 ccggcagcac gccaaggtga cgccaccacc cacggcggaa ccatcaccat cggcctgccg
     7561 acggtgatga tcggcggctg atcggatacc gcgccggacc gggcgcggta tccgcctttg
     7621 ccgggaatcg tccacccggg ccgacgggcc gggccgttgc cccggcctgc ggtgtcagtg
     7681 ggccccgggt tcagtgacgt cgctgtcggg tggttgaggg cgtgggtgga ccggtgggtg
     7741 agcgcgccgg gctcgacagc ggcgatcggt gacacgaatg ggctggaggg gttcggagct
     7801 tccgtcacga cccgggtgcc ggggcgtggc agaccgcaat ccggtccggg cgagtggtca
     7861 gggtgggggg atcgtctggc ttgtgaccag gtcccggtac ggggtgcagc gttgcaggag
     7921 tgtggggtgg tcgccggcgt cgagcacggt gccccggttc atcatgatca cgtgtcgggc
     7981 gtgctggacg gtggacagcc ggtgggcgac cacgatcacg gcgcgggtcg ccgccaggtc
     8041 ttccatgatg gcgcggaacc ggtgttcgtt gattccgtcc agctgactgg tgggttcgtc
     8101 cagcagcacg atgtcggcgt cggagaggag ggcgcgtgcc agtgccatgc gctggcgctg
     8161 tcctccggac aggtccgact cccggccgag cggtgtgtcg aggccctgcg ggaggcgggt
     8221 gatgtcatcg gtgagtccga cggcgtccag ggcggccgcc agttcgtcgg caccggcatg
     8281 gcgttcgcgg cccagctgga ggttctcccg ggcggtggcc tccagaagcg tgaatgcctg
     8341 gtcgacgtag gcgatccggg cgcgcagttc gtccagtggc cagtgtcggg tgtcgtggcc
     8401 gaggacggtg atcgagccgg aggtgggccg gatgaaccgg tcgatgaggg agagtgcggt
     8461 gctcttgccg gctcctgagg ggccgaccac ggcggtcagg ccggtgcggg cggcggtgaa
     8521 ggagattcct cgcagtgcgg ggtcgtccga tccggtgtgg gtgtaggaga ccttgcggaa
     8581 gaccacggac ggggcttgcg ggcgtggagt gggggcagtg cgcggggtgt cccgggggtc
     8641 gctttcggga gcgagcgaga ggagttcgct gcatcggtcg cgggcggcga ggctggcttg
     8701 cagccggctg aagccggtgg ccagagcgcc gatcgaggga acggtctgca acaggtagag
     8761 caggaacgcg gcgaaggccg ccacgtcgag gctgcctgcg gccagccggg cgccgccggt
     8821 gaggatcacc gcgatcatcg cgaattgatt gccgagcgac accgccggcg ggatcagggc
     8881 gttgaggcgg gctccctcca gcgagacggc ccgcagccgc tcggcggccg ccgccagtgt
     8941 gcgggcggcc atcggttcgg cccggtatgc cttgatcgtg gtgagggcct ccagattggc
     9001 cgtgaaacgc tgggagatat atcccaccgc gtcctgctgg ccgttcacat tggccttcat
     9061 ccggcgcacg accagcagca ccagaaccgt cagcacggcg aacgccacga cggtgaccag
     9121 ggtgaggacc cagtcgatcc acaccatcac gagcagcgtc gccgcgacgg tcaatgcggc
     9181 caggggaagt tgggtgacga cctcgaccgc ctgcctcagc agcagtgcgt ccgaggtgat
     9241 gcgggcggtg agttcccccg tgccctgggc acgcgccacg gacaggggca gtcgcagggt
     9301 gtggtccatg atgcgggtgc gcagccggta ggtcatccgc tcgccgatcc gggccagcag
     9361 gaagcccgac agggcctggg tgagggcgct gccgatggtg gcggcgcaca tcatcagcac
     9421 gtcggggccg agcagccggt gcgcggagaa gtcagtgatg atcttctgga ccagaagcgg
     9481 gacggcgagg gccgccgcgg tggagaccag ggcgagcaga agggcgcaga gcaggcggcc
     9541 gggctcggtg gtcagttcgc ggcgcaactg tacgcggccc ggcgcgcggt gggcggtacg
     9601 agggggctgg tcggccacgg cgtcctctct cgtggttcgg ccgtatcacg ccgccggggg
     9661 cggtcgtccg gtccggcccg tggcggcggt gtgccgccac gggcccggac gccggccggg
     9721 cctgggtggc gcccggccgg ctccgcggtg ctgtctccgt cctaccgggc ggaggtacgg
     9781 ctcagaggca gagcagggtg ctgacggtgc tgacggtgca gttgaggacg ctcagggagc
     9841 tgccggtcgc gagaacgtcg tcgatcgggg ctgcctcgga ctcgggcggc tccatggtct
     9901 ggaggtcgag gatcgccatg gctgttctcc tttgttggat cgcccggccg gcggccggga
     9961 gtcggtgggg cgcgcccggg gcgcgcgggc cggtggcccg tcagccggga gtgccggtcc
    10021 aggggaggaa aggggtgtcg gccagggctg tgcccagggc cagcagcacc ccggcggagc
    10081 cggtcgccag gtccgccgag agccgcagca gttggtcgcc ggggaaggcg agcaggccct
    10141 ggtaggagac ctggtggagg gccagcagcg cccgctgccg atccagcagg gccgttccgg
    10201 cagggtccgg cgcgcggtgc cgggtaaggg ccaggtagcc gagcagcccc gcccggccgt
    10261 tgaacaagcc cggctgaatg acgaactcgg gctcggcggc gcggcggatc gcttgctcgt
    10321 ggcaggccga gggcgcgtcg gggcggtggg ccagcagggt gttgagcgcg aggccgatac
    10381 cggcgctgcc ggtctcgacg tagggcagga ctcggcgtcc gtcggcgacc tggaaggtac
    10441 cgtcggcgag gctcgtgcac cggtcgaggt ccagttccac caaggtctgc gcctggtcga
    10501 gcagcgcgtg ttcgccggtg tgctcgtaca agcggaccag ggcgagcgcc gtaccggagg
    10561 ctccggccag caggccggcc gtgcgccggg ggtcgctgcg gccggccttc tccagggcgt
    10621 cggcgcagga gcgggcgagg accagtgcct gctccagcag ccggtgctcg ccggtggctg
    10681 cggcgaagtg caggagcgtc agggcgatac cgggcgcacc ggcggccagg cccggctgcg
    10741 gttcctcgtc cggagccgtg gccaggcgcc gcaggagcgc cagggctgcg tcgcgttcgc
    10801 cgagcaggtc cagcacatag gccacgccat gtccgccgaa gtacagtccc ggctcgacgg
    10861 ggcgggtgcg agaagcccgg accagccatc ggacgtggtc gggggcgatc gtggcgcccg
    10921 tggagtgcag ggcgtagagc acaccggccg cgccgtaggc caggcccagg ccgccgtggg
    10981 tgaactgggc gacatcgccg ggaaaaagac ggtcggttcg gtcgggggtg gccatcgccg
    11041 tgatgccggc ggccagcgag tccctgatcc gcggccagtc ggccgtcggc gctgccagca
    11101 gcgtgttgag ctgctcacgg tcgtggccca gctcgggtcg gcgggagcgg ccgtcggacg
    11161 gggcggggcc gagcaggcga cgtatctcgt cggtgtagcc gtcagggacc gggaagcgga
    11221 gctcgatggc gtcggcgagc tcatcggcct tgcccgggtc gagggcgggc agctgcgcca
    11281 gcggcaggaa cagccagagc cggatcgcgg ccagcccgta ccggtcgatc cgcgtcccgg
    11341 tgcaccccgg gggagcggcg aagccggcag cgcccagtgc cgggcggacg aagtcctcca
    11401 cagtgctggc gagctcgaag tcgatgaagc agatgtcgcc gttcgcccga atgatcagat
    11461 tgcgggggtg gaggtcgccg aagaccaccc cgcgagcatg gatcgccgcc aggacctctt
    11521 cgatgcggtc cacgatcccg agcgcctcgc gggtgtactc ggcgacagcg gcttcgtcgg
    11581 cgtccgggtg gatcagcggg tagcgggtgg ccagccactc gctcagtaat cggccctcga
    11641 cgaattcctg gaccaggaac tcgtgctccc aggcagtcag cagcccgtgc tgcgcgggta
    11701 cgccgggcac acctgccagc cggacgagga tgtcgtgctc gttgcgcagc cgggtcaccg
    11761 cgtcgacccc gcgctgatcc aggcccgcga acggccgggc ctccttcagc accagccggg
    11821 gcccaccgtc cccgtcgtgc gccaggtaca cgccccccgc gttggagaaa tgcaggaccc
    11881 gctccacggt gtacggcagc ccggtgtcgc gcgacgccgc ccgctcggcc accgcagctg
    11941 cgatgaagtc cggcaccgga gcccagtcgg ggacggcgaa tccggtgccg cggacatctg
    12001 gcaccagacg gccctcgggg ccgatgagtg cgagtacccg cgctccggcg tcgttgcggc
    12061 aatagcgctc cgcgaatccc ccgtacctca ggtagagcgg gccttcgccc catcgcaagt
    12121 cgctgaggat gtacggcccc ttgcggccgg ccaggacacg gccgaggccg tcgaggcatc
    12181 gctccaattc cgcctgatcc accgggtaga gggtgcagaa ctttccgctg gattcgcgcg
    12241 gcgcgtactt ggagttctgc acctggagga tgggcagtcc gcgcaggaac ttgaacgtga
    12301 cccgctctcg caggcagtac gcgtggaccg cctccagcac ctcttcggcg tcccccgctt
    12361 ccgaggacac gtggatcttc cagccctgcg cgggcaactg aacgtcaacg ggccgcacaa
    12421 ccgcccagat ctcctggtca acgcgttccc agcccgcagg cagcggccac tcgacggccg
    12481 cgaactcttc gtgcgcgccc cagcgtcggg gcgagtcgta aaagagcgga tcggcatagg
    12541 cataagcctc gtaccggtta tccatcaaag ccctcctcgg cgccgggtgt gcaggcatgt
    12601 gtgcgtaatg cagcaaagga gccggccgct gtcacggccc acggaacctg acgttgccta
    12661 cgcatcagcg cctgtcggca ggagagaccg gaagagccgg cccgcgatgc gactatccga
    12721 aatatggagg tggcgggaga gcaaaagcaa cagcacagac aagacaatga tgttttctaa
    12781 cggggggtga agtgatccgg gcgctcaggg ggcgctgtca agaagaggga cgggcctcgg
    12841 gactggggtg ggcatcgagt ttcttgatcg tccgggaggt gcctgctgtg aaaagcgcga
    12901 tgtgaaggcc gccaaggggt tcatggcaaa gctgatgaag gaacagcagc acgtgcccag
    12961 agtgctggtc accgacaagg ccaacgtgcg acggcggttc cgagcccgct gaccgcgggc
    13021 ggcggagtcc ggccctgtag aaatggccga agacatgcgt gagtgcctcg gggagcggcc
    13081 cgggtacgtg gtcggtgacc tcgatggtgg ccgctgtccg cggtaagcgc gaccgatacc
    13141 ggcgtcgggc cgtgccgtag tgcgttgccg acgaggttga cgctggtcac gccggagcag
    13201 cggcggtcca ccatcgccct gatgccgtcg gctccggctc ggcgaaccgc gcatcggaca
    13261 accgcggcag cctgggcggc cccttccgca cgcgccgccg gtgacgaccg ggtggcgccc
    13321 ggcgacgggg ctgggatcct gacatgcacg ccgccgcgca ccgcctccca tacctgcgcc
    13381 ctggaccgct catcaagatc ctccgggagc acctggctgg ccagctcggc gcagcggctc
    13441 gcccagctcg tggccgcggg ccgggccggc tgggcgcccc gggtgatccg cagttgccgg
    13501 caccggtcgg cgaacaagga ctccaccgcc cgcagcaggg cctcgtcggc ggcacgctcg
    13561 gcggccgcct cggccatcgc ccggttcgga taccggtgct gggaagacgt tgaattggga
    13621 aacgccacga ttgtgattgc caacacgcgc acgatgatgg gcaaccggta cgtggtggag
    13681 aaggacacca agtctcttgc gggcgagcgg gatttgccgc tgccggctcc ggtgctggcc
    13741 gccctcaagg ctttcagggc tctccaaacc gaggagaagc tcgctctggg cgaggcgtat
    13801 gtggcgtcag gccacgtgct ggtgcatgag gcgggagatg ctttcacggt caagcagcct
    13861 cgtcggcgcg cgtaccggct catggagctt ctcggcctcc gtcgcgtcag gctctacgac
    13921 gcacgctcgt cgtgcttcac cttcctggcc gacaacggcg tgccggaccg cattctcgcg
    13981 cgatgggccg ggcacacgaa ggtgaagacg accaagaggt ggtacgtcaa gccggacgta
    14041 acggatctcc gcggagccac caccacatgg gatggcctgc acggggttgc ggtggagggg
    14101 caagcgtgag ccgcgcgctc catcagtcga gcgacttgcc gagccgcatg gccaacagac
    14161 cccggctatg tgacttcccg tgacagatga gagggtctgg cgggtgagtg agacaccggc
    14221 gaacaccctc caataccgcc ttgacgggcc ggaagacgcc ccggtcctga tcctgggtgc
    14281 cgcactgggt accacctggc acatgtggga ccggcagatc cccgagctga cccgccactg
    14341 gcgcgtcctc agattcgacc tgccgggtca cggcggatcg cccgcccacc cggccgcctc
    14401 cgtcgccgag ctggccgacc ggctgatcgc caccctcgac gccctgggag tggaccgctt
    14461 cgggtacggc ggctgttcca tcggcggggc catcggcgtc cagctggccc tcacccgccc
    14521 gcaccgcctc acctccctgg cgctggtgtc ctcctcgccg cgccacggca ccgccgacgc
    14581 ctggcgccag cgcggtgtgg tgatccggac gaacggactc gacccgatcg cccgcaccgc
    14641 cccagagcgc tggttcaccc ccggtttcgc ggaggcccag cccgccatcg tcgaatgggc
    14701 cgtccagatg gtgcggacca ccgaccccgg ctgctacatc gccgcctgtg aggcgatggc
    14761 ctccttcgac gtgcggtccg cgctcggccg ggtcggcgtg ccgaccctcg tcgtcgtcgg
    14821 ttccgcggac cggaccaccc cgaccgccga cgcccgcacg ctggtcgccg gcatcccgga
    14881 cgccagcctg gcgctggtgc ccggcacctc gcacctcgcg cccgtcgaac agcccgcggc
    14941 cgtcaccgac ctcctcatcc ggcacttcac caccgcctgg caggaccggc ccggcggcgg
    15001 cccggccgcg cccggcgcca ccgcgaacac accggtgctc gcgcccccgc ggcccccgca
    15061 gccggtcccc gccgccatcg agtccggtct cgcccagccg gcgcggctcc gcggcagcac
    15121 ctacgagcag ggcgtcaaga tccgccgcga ggtgctcggg gacgcccatg tcgaccgggc
    15181 cgaggccgcc accgacggct tcaccgacga cttccaggac ttcgtcatcc gctacggctg
    15241 gggcgagacc tggagccgcc ccggtctgga ccggcgtacc cgcagcatcg tcacgctcac
    15301 cgcgctggtc gccggcggcc accacgacgc gctggcgtcg cacacccgcg ccgcgctgcg
    15361 caacggcctc accccggtgg agatcaagga gatcctgctg cacaccgcgg tctactgcgg
    15421 ggtgccggcc gcgcacgccg ccttcgcggt cgcccagcgg gtcatccggg aagagaccac
    15481 cccggaaggc tgacccggcc ggaccacgcg cccgtggccc agtggtgcgc ggcgcgccgc
    15541 cccgggcggc cgcggcgtcc cgggcgcggc aagatggcgg ccatggaact cacgaagaag
    15601 acccatgcct gcgtccggct ggagaaggac gggcagacgc tcgtcatcga tccgggagtc
    15661 ttcagcgaga cggacgcggc cgtcggcgcc gacgcgatcc tggtcaccca cgagcacccc
    15721 gaccacttcc acgaggaccg gctgcgcgcg ggcatggcgg ccaatccggg cgccgagatc
    15781 tggaccctcg ccagcgtcgc cgagcagctc gcggccgcct tccccggccg ggtgcacacc
    15841 gtcggcgagg gcgacacctt caccgccgcg ggcttcgacg tggaggtgca cggccagctg
    15901 cacgccgtca tccaccccga cctcccgcgc atcaccaatg tcggcttcct gctcgacggt
    15961 tcggtcttcc accccggtga cgcgctcacc gtgccgcagg gccgccgcgt cgacaccctg
    16021 ctgctgccgg tgcacgcccc ctggaacaag gtcgccgaga tcatcgacta cgtccgcgag
    16081 gtcgcaccgc ggcgcgccat cgacatccac gacagcctgc tccaggacca cgccaggccg
    16141 atctacgacg ggctgatcgg cgggctcggc ggcgccgacc acggccgcct cgcgcccggc
    16201 gcccacaccg acgtcggctg actgtcggtg cctcgcggta ggttacggac atgcgcatcg
    16261 cgacctggaa cgtcaactcg atcaccgccc gtctcccgag gctgctggcc tggctggaga
    16321 gcaccggcac ggacgtgctg tgcatccagg agaccaagtg cgcggcggac cagttccccg
    16381 tcggtcagct gcgcgagctg ggctacgaag ccgcggtcaa cgccaccggc cggtggaacg
    16441 gcgtcgccgt gctctccaag gtcggcctgg cggacgtcgt cacgggcctg cccggcggcc
    16501 cggagtacga cggcgtccag gagccgcgcg cagtctccgc gacctgcggc ccggcccgca
    16561 tctggtcggt gtacgtcccc aacggccgcg aggtgggcca tgagcacttc tcctacaagc
    16621 tgcgctggtt cgaggcgctg acggcggcgg tcgccgagga cgccgcggcc ggccgcccgt
    16681 tcgcggtcct cggcgacttc aacgtggccc cgacggacga ggacgtctgg gacccggcgg
    16741 tgttcgaggg cctgacccat gtcacccccg ccgagcgcga cgccctggcc accctgcgcg
    16801 ggacgggcct gacggacgtc ctgccgcgcc ccctgaagta cgaccgtccg tacacgtact
    16861 gggactaccg ccagctcggc ttccccaaga accgcgggat gcgcatcgac ctcgtctacg
    16921 gcaacgcccc gttcgccgag gccgtctcgg acgcctatgt cgaccgcgag gagcgcaagg
    16981 gcaagggcgc ctcggaccat gcgccggtcg tggtggatct ggacgtctga cgcccgcccc
    17041 ggccccggca ccctcccggg gccggtgatc cggtgtcccg gcgcgccgtc gccgtacgcg
    17101 tgcgccggcc cgtcgtgccg ccgggcggat cggccaagag cgcgggagca caaggcggtt
    17161 gccgcgcgcc ctgtggccgc cgccccgggc cggatgcgac cctgcacacc atgaacatgt
    17221 ctttcctgga caagtggcgc cggcatccgg acgcggaccg ccggctatcc ctcgcggaat
    17281 cggtccgcgc cgaccccggc agcgtcgtcg agctgctctc cgaatgcgaa ctgctgcggg
    17341 cgcaggccgc cgactcgggc gtggaactcg acgactccgt acggtcgttg gaggagctgg
    17401 accaattgca gccggtgtgg cgggacgacc ccgaagtgct gccctggctc ggcaacgacg
    17461 cgggtctcta tctgggcacc gtcctcgtgc gtacggtgcg cggcgccgtg tggcaggtgc
    17521 ggcaggacgg ccggccggtg gtccggctgg cgtccggccg ggagatcgat gtcgtcgcgg
    17581 cgggccagga ctgggccgat gtcggggcgc ccgagctgtc ccaggagtac gccgaggtcg
    17641 ccgagagctg acgcccgcgg agcgtacgcc cgaggcatcc ggcgcggccc ccggcgcccg
    17701 gtgccgccgt cccggcgcca cggccgaacg cccctggagc ggtcttccgt gacccggcgt
    17761 acgcctggtc catccgcccg cttctgctcc tctgtgcgtg tcaacgatca ggcgtccctt
    17821 ttgtcccggt aagttgcggc tctccgcggt acggatgaga gggagcaggt ctgcatatgg
    17881 ccggtgaggc gctgatcgaa ctgcgcgggg tcaacaagta ctacggaaag ctgcacgtcc
    17941 tccaggacat cgacctcacc gtcggccgcg gggaggtggt cgtgatcatc gggccctccg
    18001 ggtccggcaa gtccaccctg tgccggacca tcaaccgcct cgaaacgatc gagtcgggca
    18061 ccatcatgct ggacggcaca ccactgcccg acgagggccg cgcgctcgcc gagctgcgcg
    18121 ccgaggtcgg catggtcttc cagtccttca acctcttcgc gcacaagacc gtgctggcca
    18181 atgtgatgct ggcgcccgtc aaggtccgca aggtcaagaa ggaggatgcc gcccggcggg
    18241 cccgggagct cctcgaccgg gtcgggctcg cctcgcaggc cgagaagtac cccgcgcagc
    18301 tctccggcgg ccagcagcag cgggtggcca tcgcccgcgc gctcgccatg gacccgctgg
    18361 cgctgctctt cgacgagccg acctccgcgc tcgacccgga gatgatcaac gaggtgctgg
    18421 aggtcatgca gcaactcgcc cgggacggta tgaccatggt ggtcgtcacc cacgagatgg
    18481 gcttcgcccg ctccgccgcc aaccgcgtgg tgttcatggc cgacggccgc atcatcgagg
    18541 accgcgcccc cgaggacttc ttcaccgcac cgcgcagcga ccgggcgaag gacttcctct
    18601 ccaagatcct caagcactga acggcccgcc gcgatgccgc actcccgtac tccgcgcctg
    18661 cgccgcgccc tgctggccgc cgcgctcacc ctcctcgcac tggccaccgc cgccggctgc
    18721 ggccgcaacg gcagcccacc ggtcaagagc cccaaggccg gcgaactgcc ccactacccg
    18781 gtcgccgaga acttccggct gccggactcg cccacctggc gacgggccga agcgcgcggc
    18841 catctcgtcg tcggcgccaa ggaggaccag ccctacctcg gcgagcggga cccggccacc
    18901 ggcacgtaca gcggtttcga catcgagatc gccaagatga tgtcggccgc cctcggcttc
    18961 gaccccgcga cgacccggtt caagacgatc gcctccgcca accgcgagac ggccctgcag
    19021 aacggccaga tcgacttcta cgtcggcacc tacaccatca acgccctgcg caagaagcag
    19081 gtcggcttcg ccgggccgta ctacctggcc ggccaggggc tgctggtgcg caccgacgag
    19141 aaggacatcc acggaccgca ggacctggcc ggcaaacgcg tctgctcggc cgccggttcc
    19201 acgcccgccc agcgcatcgc ggccgactac ccccaggcga ttctggtcac ctacgacacc
    19261 tactcggtgt gtgtggacaa cctgctcacc taccaggtgg acgcggtcac caccgacgac
    19321 gcgatcctgc tgggctacgc cgccaaggcg cccgacgagc tgaaggtcgt cggcaaaccg
    19381 ttctccgagg agccgtacgg catcggcgtc ccccgcgaag acaccgcact gcgggccgcg
    19441 ctcaacgacg ccctcgtcgc cgccgagcgc gacggctact ggaagcgggc gtacgaggcg
    19501 acgctcggcc tgtccggagt acccgcaccg cagccgcccc cggtcgaccg ctacccggcg
    19561 ggctgagcag caaggacccc acgatgaacg ttctcctcga caatctctcc ctctacgggg
    19621 agggcctgct gggcaccgtc gaactcaccg tctacgcctc gctgctcgcc ctcttcctcg
    19681 gcttcctgac ggccgcctgc cgcgtcgcgc cggtccgctc gctgcgggcc ttcggcacgg
    19741 tgtgggtgac ggtgctgcgc aacaccccgc tgacgctgct gttcttcgcg gtgctgctgg
    19801 ggctgccgcg cttcgggctg gtgctgccct tccagatgtt tgctgtcctc gccctcggct
    19861 gctacacctc cgccttcatc tgcgaggcgg tgcgctccgg catcaacacc gtgccggtcg
    19921 ggcagggcga ggcggcccgc agcctgggca tgaccttccc gcagacgctc ggcgacgtgg
    19981 tcctgccgca ggcgttccgg acggtcatcc cgcccatcgg ctccaccctg atcgcgctcg
    20041 ccaagaactc cgcgatcgcc ggctccttca gcgtcgtcga actgctcggc acgtaccgga
    20101 cgctcagcga gctgggctac agcatcatct ggaccttcat ctggatcgcc gtcggctatc
    20161 tgatcgtgac cctgtccatc agcgcgctgt tccacgtgct ggagaagcgc tggggagtcg
    20221 cccgatgacc accgccctct acgacgtacc ggggccgaag agcaagcggc ggcatctgct
    20281 ctacggtgcc gggtcgaccg tggtgctcct cggactgctc ggctggctcg tctacctcct
    20341 cttccacacc ggccagttca ccgcccagaa gtggactccc ttcctctaca agggaattca
    20401 ggagctgctg ctgcggggcc tgggcaacac gctccgggcg ttcggttacg cggcggtgtt
    20461 ctccctggcg ctcggcgcgg tgctcgcgac cggccggctc tccgtgcacc ggccggtccg
    20521 ctgggtgagc acggcgctgg tcgagttctt ccgcgcgatg cccgtactgg tcatgatctt
    20581 cttcatctat gtggcactga aagcggaacc gctgaccgcg ctggtcgccg ggctgaccct
    20641 ctacaacggt tcggtgctcg ccgaggtctt ccgtaccggt atccacgcgg tcgagcgcgg
    20701 ccagggggag gcggcctacg cgctgggcat gcacaagacc caggtcatga cgcacgtcct
    20761 ggtgccgcag gcggtccgcg cgatgctgcc gacgatcatc agccagctgg tggtcgccct
    20821 caaggacacc tcgctcggct acctgatcac ctacgaggag ttcctgcacg ccggcaagct
    20881 catcgccgcc aacctcgact acggactgcc gttcatcccc gtcgtcatga tcatctcgcc
    20941 gatctacatc gggatgtgca tgctgctgtc ctggtgcgct cactgggtcg cccggcgcca
    21001 gcggcgcaac cccaaggtcg aggcggtgga ggtgggtgcc gcggagccgg gcaccctgct
    21061 cccgggcggc ccgtaggggg cggtgcacag cacgccccgg ccggccggtt ggcgcggccg
    21121 gcgggcgagc cgcggcgggc gcggctcagc ggaaggtgcg ggccatccag gggctgaggc
    21181 cgcggaagat cagttccttg taggtctcgt cgccgggcag cggcacgacc agccactggc
    21241 ccggcgggaa ggtccgcccc ttcacatggg cgagcccgcc gtacaccgag cgcaggaacg
    21301 cgggcaccga gtcccggggg acgtccggga acgtcaccga gtcgacggtg atccgcgcat
    21361 cctcctccgg gaagatctgc acgctgaccg cgggcgaccc gcccagctcg acgaacgcct
    21421 cgtggggcag cgagccgtcc gcgtccagca ccgtgaacgc cccggacgag gtacggcggg
    21481 acgtctggtc cgcgccgatg tcgtccgtga cggtcagctc caggtggtac tcgccggcga
    21541 tctcgcggat cgcggtgacg gcggcctcgg tggtcggcag atgcgggtgt cccatgagaa
    21601 ggatcatgcc ttatgggacg gttgccctcc ctcgcggacc ggcaccgaga catacgacgg
    21661 gtcatcggcg ggcgaggaga acgtcagccg cgcgccgctc ggattgtgct cgatgtacag
    21721 cggatcgacg gtgtccacga ccaccgcgag ccggtgcccg gccggtacgt cgtacgccgt
    21781 ggagaacagc tccaggtcca cgccgaacgg ccggccgggg gtcttgccgt ggaaggtgaa
    21841 cggcgcgtgc gagaccagct tgccgagacc gagcgggccc acgtcgtaga ggtaggcgat
    21901 ggcggtcccg ctctcggcgg tgccggtcac cgtcgtgtgc agccgggtgg tcccgcggac
    21961 ccgctgttcg ctcgcgtagc gcccggactc ccagacggcg gccacggagc gcggcagcag
    22021 cgggatcgag gccatcggcg gcagccggaa gaactggtcc agcatgctgg agaggaagac
    22081 cagcccgccg ttggcgccgg agtcgatgtt ggtgcggatc cgctgggtgc cggtcagctc
    22141 gatcttccgg tgcccggacg gtacgtcccg ccagctctgg tacccctcgt acgcgccggt
    22201 ggagcgggac ttgagcagca ccggcgccgc ccggtcgatc ccgttgtccg tgcccttgag
    22261 gtagtggtcg aaccactgct tggtgtggct ccaggtgtcg ttgggcagcc ccagcagccc
    22321 gagcccctcg gcggtcgcat ggtcaccggg gcggaactcc agccgcttgg ggccggtcag
    22381 cttctcgtag aagtcggcgt actggttggg cggaaacagg gagtcgcccc aggcgttgcc
    22441 gagcatgatc gcggcgccat tggcgttgat cttgtcgatg taggtggcgg gggagcgctt
    22501 cttcccccag gcgatcatgt cctgctcctt ggcgaggttc gagccgagga agtccttgag
    22561 gatgc
//
