LOCUS       NZ_NDXL01000001        22532 bp    DNA     linear   CON 27-APR-2024
DEFINITION  Streptomyces kasugaensis strain BCRC 12349 scaffold1, whole genome
            shotgun sequence.
ACCESSION   NZ_NDXL01000001
VERSION     NZ_NDXL01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces kasugaensis
  ORGANISM  Streptomyces kasugaensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 5071473)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Comparative genome analysis for kasugamycin overproduction
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5071473)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Comparative genome analysis for kasugamycin overproduction
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 5071473)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030,
            China
REFERENCE   4  (bases 1 to 5071473)
  AUTHORS   Liu,X., Zhu,C., Bai,L. and Jiang,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2017) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. May-2015
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 188.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002261115.1-RS_2024_04_27
            Annotation Date                   :: 04/27/2024 02:42:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,951
            CDSs (total)                      :: 7,863
            Genes (coding)                    :: 7,657
            CDSs (with protein)               :: 7,657
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 4, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 206
            CDSs (without protein)            :: 206
            Pseudo Genes (ambiguous residues) :: 0 of 206
            Pseudo Genes (frameshifted)       :: 87 of 206
            Pseudo Genes (incomplete)         :: 170 of 206
            Pseudo Genes (internal stop)      :: 23 of 206
            Pseudo Genes (multiple problems)  :: 65 of 206
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:37:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3297916
            Orig. end                         :: 3320448
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NDXL01000001.1.
            Bacteria and source DNA available from BCRC.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22532
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="19"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22532
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22532
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12532](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12532)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(67..85)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 27.44"
                     /tool="antismash"
     misc_feature    complement(69..89)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
     misc_feature    complement(84..98)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.89"
                     /tool="antismash"
     misc_feature    291..305
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            complement(402..1241)
                     /locus_tag="B7024_RS14160"
     CDS             complement(402..1241)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018892384.1"
                     /locus_tag="B7024_RS14160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_052861426.1"
                     /transl_table=11
                     /translation="MPGDSPLRFVALGDSQTEGLGDGDDTVGLRGWADRLAEQLALHNS
                     GVRYANLAVRGRLARQVREEQLAAALALRPDLATVVAGVNDLLRPRFDADEVAGELEAM
                     FAALTAQGARVATLTFPDMARITPLARPVSSRISALNHRIRQAAHRHGVTLAETAHHPV
                     VTDPRLWSPDRLHASPLGHERIAAAVAHALDLPGSDDSWTRPVAGPRPATPTGWRTAAD
                     ELRWAASFLGPWLGRRLRGQSSGDGRTAKRPDLRPVHTVPARGGAEWNGAGDAPSSS"
     gene            complement(1228..1797)
                     /locus_tag="B7024_RS14165"
     CDS             complement(1228..1797)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009720594.1"
                     /locus_tag="B7024_RS14165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_052861428.1"
                     /transl_table=11
                     /translation="MALRHAVLAALLDEELSGYQLAKAFDTGVANFWHALPQQLYAELA
                     KLEKEGLVAGREVVQDTRPNKRLFQVTDAGLAELDEFATATAKPSFIRDDLFVKVQAAD
                     HLDTDVLVAQLTERAVFAEAKAELFDVLLRKMRGDRDEEEFLRHGERIGPYLTCRRGLD
                     FERSNRDWCRRTAEVLRERQAARARR"
     gene            complement(1918..>2214)
                     /locus_tag="B7024_RS14170"
                     /pseudo=""
     CDS             complement(1918..>2214)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019063678.1"
                     /locus_tag="B7024_RS14170"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LASAAGLVPVPRDSGWRTGNLHRPKRYSRRLRRVFYMSAQTSIIR
                     EGPNRDFYLKKRAEGCKHVQAVIALARRRANVLWALLRDGRLFTSAPPVTQAA"
     gene            2387..3058
                     /locus_tag="B7024_RS42390"
     CDS             2387..3058
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS42390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_244933926.1"
                     /transl_table=11
                     /translation="MAALAVVRDLREHWAPASAEELEQFETDALSGFVLARASAGLADG
                     TIRGDVGHLDQIRTWFGRPLWDMEPADADAYFGKVLRGSPSGTRLARSQALTTYFMFLE
                     LRHKVELHRITGRAIECPIDEMNRPRGAKDAQLRIPPSEPELGRLFTGWGGELANCRKF
                     APTARNYTASKLMSQVGLRVSEACKLDLDDIKWDLGRFGKLHVRYGRAPAVRGRASGWC
                     R"
     gene            3046..3465
                     /locus_tag="B7024_RS42395"
     CDS             3046..3465
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /locus_tag="B7024_RS42395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="site-specific integrase"
                     /protein_id="WP_244933927.1"
                     /transl_table=11
                     /translation="MVPLINGADRTLRWFIEDVWGQFDDDHTRPGAPLFPSERKNTDGS
                     SRRVGDDALRGGLKDAAKLHLPGWGERLTPHVLRHFCASQLYGNGLDLLAIQEVLGHSW
                     IATTMRYIHVQQTRVEDAWVAGMERAAKRLEGLVR"
     gene            3462..3788
                     /locus_tag="B7024_RS14180"
     CDS             3462..3788
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057696.1"
                     /locus_tag="B7024_RS14180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_094792135.1"
                     /transl_table=11
                     /translation="MRWNLRLTAANKGIWKASELQRSLAEHGLVISAGKMSGLWSGQPV
                     SLKLDDLDVICVVLGCEVGDLMIPEPDKVRRPGEETGQQAAVASGSAPAVVPRRRDGRS
                     LPPA"
     gene            4164..5378
                     /locus_tag="B7024_RS14185"
     CDS             4164..5378
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018553050.1"
                     /locus_tag="B7024_RS14185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_244933928.1"
                     /transl_table=11
                     /translation="MFEVRRAFPGRKAADEYAQYGNPWLAWARHSAHRLGEARGWPRQT
                     RLNVDQALILVLAGHADGDTVRYSEIFPVLRARGLSVERTTEVLDHIGVFLDDRPSSFE
                     QWLEAKLDGLATGVARDVGEWARLLHDGGPRSRARDVATVWNYLNRIRPVLLEWSNRYD
                     HLREVTRDDVLTCLDTVQGAHRQATIVALRSLFRQAKKNGTIFKNPTSRIRVGQREEGV
                     IQPLEPHHVNGSVAAVTHPADRLILALAAVHAARPAAIRRLQLDDLDIGNRRMTIDGHA
                     RPLDDLTREVALEWLEFRRRRWPNTANLHLLINKQTALGTGPISKSSVAGPALHGQTAT
                     LQRLRMDRQLEEALVHGPDALHLAEVFGLSEKTAIRYANSARALLERPLESDPAASPRT
                     HGSTP"
     gene            5545..8799
                     /locus_tag="B7024_RS14190"
     CDS             5545..8799
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033527.1"
                     /locus_tag="B7024_RS14190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Tn3 family transposase"
                     /protein_id="WP_094792137.1"
                     /transl_table=11
                     /translation="MLTVVWGLGWVVTSIERTAYPRFKRLITAHELHLFFSPTRDELEW
                     AADRTDSDEHLLALLLTLKSYQRMGCFPKVEDIPEAVAEFVRRAVELPEGTLPVYRAAK
                     TMKNHRGLVRQRVGVAYDQGKARRIAEASIRKEAAAKNRPADLINIALEKVVEAGLELP
                     AFSTFDAMASTLRREVNAEICAGIHERMSAPERAGLLRLLEERMSDGTTLFNRLKKPAQ
                     GPTWSHFKNLANRREWLDELGDTDVWMEGVAAGKITDFAGEADAADVAELRDYRPVKRL
                     ALVACLAHKARMRVRDDLATMFCKRVAMKIKKAKAELEEIRLAEREITEALIGNYRTVL
                     KHIDEGGPAQEALERAAAMTAEARQALEGLDEEASVDEVAKRLEGRVSPAVLALVKAQM
                     VQAGGFGAVTRAVEGFGGFAKQYEQIEKVSAHHGNFWEVLLYGQFGRDRAVMFDLAGAE
                     KLEFTATSEDFRVLDALAHAQRHQAARGEYITAFNEEGKEVDISFATQNWRKAVLDKTR
                     PGQFVRKHFEAMVFTALAEELRTGDVAVVGSEEYADWSEQLLAWEAVQEKLGSYLVEVG
                     LAEPGESAEFDAKFFRRQLEDKLRNAAAAADAGYPENEGLVIDPETGIPSLKAFRADGQ
                     RPSAKRLEQEIKARMPERSLMGIVARTAYWVEWWRRFGPPSGNEPKLTDPLGRYVITTF
                     VKGTNMGPYEAARHIPGVSGHELSYVANRHFSIVLLNEAISDLVNAHARLDISQAWGDG
                     TAVAADGTHMDTYLDNLLSETSVRYGKPGGIAYHHVSDTYIALFTHFIPCGVWEAVYII
                     EGLLKNTSEVKPTTVHADTQGQSFPVFALAHLLGFDLMPRIRNWKELTFYRPSKQSEYV
                     HIDALFGEPSKNVIDFDLIESQFRHLMRVAVSVREGTISSSTLLKRLRSGSRKNATYAA
                     FREVGRVIRTVQLLRYLSDAPLRRRVTAATNKVESFNRFSQWIGFGNRGVIADNDPIEQ
                     EKAMKFNALLTNAVIFHNALDIAEIVRQLLDEGWEIDPEDLAHISPYLTEHINRFGEYS
                     THELGIQPDAYDPKLDVDFTPLREQDLTTAGLGQAA"
     gene            complement(8911..9921)
                     /locus_tag="B7024_RS14195"
     CDS             complement(8911..9921)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013315.4"
                     /locus_tag="B7024_RS14195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="protein-L-isoaspartate(D-aspartate)
                     O-methyltransferase"
                     /protein_id="WP_094792138.1"
                     /sec_met_domain="PCMT (E-value: 7e-24, bitscore: 82.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVALAAETVPERHYTHHEGRGATPHRSNPAVIHRELTTLGVES
                     GMNVVEFGTGSGYSGALLAELVGPTGHVTSLDIDTYLTRWAGLIHHQRGVDHVRCHAAD
                     GTGGFPERAPYDRMVAWCTPPLLPKAWVDQVADGGLIVAPLPIAAVPNMTVVAKIRVTG
                     GEPVVEEVFTGGYIEATSSPKTDLDLPGRWVDWENRIPAPSWISIAWRSEDDHLHTGAR
                     TALERLLKNAHTEPYAGAEIDLPSWRTFAATRGDHRLTMAGLSPDLWAIGHTTTTTAAV
                     IQQDGTILADAPDSPSLTVLRTWLGQWEEAGRPAPSTYTPALVRTGEGWDLRLSR"
     gene            complement(10001..10414)
                     /locus_tag="B7024_RS14200"
     CDS             complement(10001..10414)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="B7024_RS14200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_094793186.1"
                     /sec_met_domain="PF13471 (E-value: 9.4e-12, bitscore: 43.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAYSTVRTGTFPERCAAAAGLALALVLLRLPFRHTVRTVRWARR
                     VGRRPLAPERAGALVEAVRHTGHLWPGRAACMETSLGAVLAAALLGRRLDWCLGARFAP
                     PPVEYHAWAELPGHGPVGEYTAGGWHHRTALTI"
     gene            complement(10420..10713)
                     /locus_tag="B7024_RS14205"
     CDS             complement(10420..10713)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.4"
                     /locus_tag="B7024_RS14205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PqqD family peptide modification chaperone"
                     /protein_id="WP_094792139.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.9e-12,
                     bitscore: 45.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.1e-07, bitscore: 29.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWQLRESAHPVLTDEGGAILDERTGRWTHLTPTASAAVMLLLAGT
                     TEEEAAGQYAERYGIPAGQADADVRTVADALTAQGLGAAGPASRRRWWGWWR"
     aSDomain        complement(10471..10707)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_B7024_RS14205_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.30E-14"
                     /identifier="RREFam002.1"
                     /label="B7024_RS14205"
                     /locus_tag="B7024_RS14205"
                     /protein_end="81"
                     /protein_start="2"
                     /score="45.0"
                     /tool="antismash"
                     /translation="QLRESAHPVLTDEGGAILDERTGRWTHLTPTASAAVMLLLAGTTE
                     EEAAGQYAERYGIPAGQADADVRTVADALTAQGL"
     gene            complement(10697..12532)
                     /locus_tag="B7024_RS14210"
     CDS             complement(10697..12532)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033561.1"
                     /locus_tag="B7024_RS14210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="albusnodin/ikarugamycin family macrolactam
                     cyclase"
                     /protein_id="WP_094792140.1"
                     /sec_met_domain="Asn_synthase (E-value: 2.2e-25, bitscore:
                     88.0, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRWSAGRYGSAEEARRPRGGHPVPGVEAAWTAGWPTRRVLSVSQG
                     PVSLAVIGDCGADDDQLAARLPAVRAGRWRELTRWPGSYLAIARNGATLAVIGDLAGQH
                     PVYWRSHGGVVWWATSALALAALDGAPVDPTALAAHLALAQPDVLRQHSLLRCVERVPG
                     GHLLLVDDKGARTVRFEPAEYGRVDLPVAAATVRAALSEAVATRLDERPVSADLAGLDS
                     TTLACLAATRGPVTAVTFADERLRDDDLPYATRTAATVPNLTHHPVPGTANTVYYDGLD
                     DLSRLPVTDAPNAYAVTASIKRAVLDTVAAHHPVPGLHLTGSAGDAVLSAPSSYLADLL
                     RERQHRRAWSHALGHARLRHTSAWSVLGRSRPASRTGLAGAWRQTAAELRGPVREWVPQ
                     AVRPVAWTPLLATADWMSPDVRHQLAAALDRAAGQLHDAPARLAAWSDWQDLARLGADT
                     TGWRQIASAEYGVDLVAPYLDNEVIRACLAVPADQRGAPGRYKPLLTTAFTGTGVLPDF
                     VLNRTTKGGFNALAYAGLRENAPVLLDLLGASSRLAAAGLVTEQPVARMLQRAAAGQPT
                     AQGALHLAVAAEVWLRQLDTTAPTWWEVNSRVAAA"
     gene            complement(12691..12819)
                     /locus_tag="B7024_RS41330"
     CDS             complement(12691..12819)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="B7024_RS41330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_172450634.1"
                     /transl_table=11
                     /translation="MEHTTQTPAYQAPIVLDAGDVVEVTLGTQNFDTADDTQYKNA"
     CDS_motif       complement(12742..12819)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MEHTTQTPAYQAPIVLDAGDVVEVTL"
                     /locus_tag="B7024_RS41330_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(12691..12741)
                     /prepeptide="core"
                     /locus_tag="B7024_RS41330_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="0.80"
                     /molecular_weight="1770.8"
                     /monoisotopic_mass="1769.7"
                     /core_sequence="GTQNFDTADDTQYKNA"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MEHTTQTPAYQAPIVLDAGDVVEVTL"
                     /leader_location="[12741:12819](-)"
     gene            13018..14394
                     /locus_tag="B7024_RS14215"
     CDS             13018..14394
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521721.1"
                     /locus_tag="B7024_RS14215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_094792141.1"
                     /transl_table=11
                     /translation="MTQRLPNARLRDAVAESGWTYAALAHAVRQVAAENGASLRTNKST
                     VDHWIAGAMPSGQTGRYLTIALSRRLGRTLTPEDLGLPVPAGWENDSIGLSIGDDPLEA
                     LMPIWRGDLDRRRFLSGAAYSVAAAVLPLEHVTDIASRAAKARTGAIVGHADVAAVRDM
                     VAMFAVMDERHGGQHGRSALVQYLMSDVAALCRGRFSSEDDHRHMLSAAAVGVHQAGWR
                     AYDGGEQGLAQRYYLQSYALAHESGITGHDAFVMRTMSQQGMKLHRPEHCLALAASAVD
                     KVRGRVDAQTEALFAVTHAHGLAKAGQRTEAVREVERASTALGSAKGDEVPFWALSWGP
                     PAATVHSRTAKVFETLGDRRRAAAMYGAAATSRPPGTYARIVALDLVAQAEMQAAEGSI
                     EQACATWGRAIDHMDGVQSGRTRKAVGNMRRDLSRFRTRGLRCATELDERARDFLSDRR
                     "
     misc_feature    13030..13032
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14510..14677
                     /locus_tag="B7024_RS41335"
     CDS             14510..14677
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS41335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_172450637.1"
                     /transl_table=11
                     /translation="MNYHPQYRAKGAPVLGVPHGTPGPFGVHRPDEDTDEQPQDKYAAA
                     VPAPRDGRER"
     gene            14674..14910
                     /locus_tag="B7024_RS14220"
     CDS             14674..14910
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS14220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_094792142.1"
                     /transl_table=11
                     /translation="MSGIWRQVLAAYTTGQHDERDREQLLALGAAELAHARSEEDQPAT
                     AEDVQRIALHEFGLLLGVTQARTALRERRTRHG"
     gene            complement(15500..16108)
                     /locus_tag="B7024_RS42400"
     CDS             complement(15500..16108)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS42400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_244933929.1"
                     /transl_table=11
                     /translation="MSGFARDTKYYGDRLVYEPLESKWSRYHAYHCGCGQDWLTAHAIP
                     AGFTVLPRGKTGYYGLVGPGLTEGVDESALTANALWEAVTGKPGTQSWHEGVHITCRSP
                     ESEAKRKAANDEYYGRIREESAKRKAAAQKTPITPAQLKYLTRLVEKAGKERFDAEYVK
                     AVKGTDIKPRAPRERTATASKRLTKAAAHKLIGALLDAP"
     gene            16372..17382
                     /locus_tag="B7024_RS14230"
     CDS             16372..17382
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016579330.1"
                     /locus_tag="B7024_RS14230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="recombinase family protein"
                     /protein_id="WP_094792143.1"
                     /transl_table=11
                     /translation="MDLTPDQAALAVERHDCPNCDAPAGSACRTRGGKTAAKYHTPRFV
                     LVPALREELEIPVPADRAPGRAWKQGPALAVVPAPRTERPVRIGYARTSTARQELASQL
                     EALHRAECHKVFKEQISTRIKVRPELEKALALAHQFKEAAPETPVIFTVHELKRLARNA
                     AELMTLSAELQAGGIQLELLTGPLTGIYDPNGMGAMFFAVLAVAGQIERNYIREKTLEG
                     QVIAASKGNHGGRPKVIDEDMLTFAVALKDKGVPVPEIAKKLIIKVGKNAGKSPSVASL
                     YRALAEVEQQEPAAEPRVIEQPRPRPARITGPDSETDPELMRRLEQQVLGQRSKR"
     gene            17387..18106
                     /locus_tag="B7024_RS14235"
     CDS             17387..18106
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS14235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_143682096.1"
                     /transl_table=11
                     /translation="MAADPGRALMFHPGTTVQYLALSEHWGAYGIVAGGVGDGATYTID
                     LLPPRTGTAVWGHTSVVRVFDAPAAAETLSPIHPAGTVPIPGLRPVLRRRRPPLPRPVV
                     GSLAEAVAVADWRPEYSPYGDPDSWTPVGEGAHRAVILNPARTTVYKIETQAGRNQREH
                     RTLGGLRHQGYSHAPPTTLWTVPGPAHHSVVLAMPYLPNDGTASRTPYPRAGVTDLNPA
                     NVTVCRSQYWLIDASGL"
     gene            18532..18942
                     /locus_tag="B7024_RS14240"
     CDS             18532..18942
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS14240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_094792145.1"
                     /transl_table=11
                     /translation="MASLLREAAALLRRHAAEATEFPDERWMVDQDETGGLVLVAFTPE
                     DVEPDGTVSSGILASFAYPDNAERATHARALAAASHTAALDPQAAWMLAAWLETTASFE
                     DRAEELGDVEGAAPLIDPATRFARAYVRNAET"
     gene            complement(19034..19177)
                     /locus_tag="B7024_RS41340"
     CDS             complement(19034..19177)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS41340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_172450640.1"
                     /transl_table=11
                     /translation="MSDEQNSRVWWGWVARFRERRRDRPSARRRLSLDEAAERAADYLE
                     GR"
     gene            complement(19296..20510)
                     /locus_tag="B7024_RS14245"
     CDS             complement(19296..20510)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018553050.1"
                     /locus_tag="B7024_RS14245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_244933928.1"
                     /transl_table=11
                     /translation="MFEVRRAFPGRKAADEYAQYGNPWLAWARHSAHRLGEARGWPRQT
                     RLNVDQALILVLAGHADGDTVRYSEIFPVLRARGLSVERTTEVLDHIGVFLDDRPSSFE
                     QWLEAKLDGLATGVARDVGEWARLLHDGGPRSRARDVATVWNYLNRIRPVLLEWSNRYD
                     HLREVTRDDVLTCLDTVQGAHRQATIVALRSLFRQAKKNGTIFKNPTSRIRVGQREEGV
                     IQPLEPHHVNGSVAAVTHPADRLILALAAVHAARPAAIRRLQLDDLDIGNRRMTIDGHA
                     RPLDDLTREVALEWLEFRRRRWPNTANLHLLINKQTALGTGPISKSSVAGPALHGQTAT
                     LQRLRMDRQLEEALVHGPDALHLAEVFGLSEKTAIRYANSARALLERPLESDPAASPRT
                     HGSTP"
     gene            complement(20886..21212)
                     /locus_tag="B7024_RS14250"
     CDS             complement(20886..21212)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057696.1"
                     /locus_tag="B7024_RS14250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_094792135.1"
                     /transl_table=11
                     /translation="MRWNLRLTAANKGIWKASELQRSLAEHGLVISAGKMSGLWSGQPV
                     SLKLDDLDVICVVLGCEVGDLMIPEPDKVRRPGEETGQQAAVASGSAPAVVPRRRDGRS
                     LPPA"
     gene            complement(21209..21628)
                     /locus_tag="B7024_RS42405"
     CDS             complement(21209..21628)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /locus_tag="B7024_RS42405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="site-specific integrase"
                     /protein_id="WP_244933927.1"
                     /transl_table=11
                     /translation="MVPLINGADRTLRWFIEDVWGQFDDDHTRPGAPLFPSERKNTDGS
                     SRRVGDDALRGGLKDAAKLHLPGWGERLTPHVLRHFCASQLYGNGLDLLAIQEVLGHSW
                     IATTMRYIHVQQTRVEDAWVAGMERAAKRLEGLVR"
     gene            complement(21616..22287)
                     /locus_tag="B7024_RS42410"
     CDS             complement(21616..22287)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B7024_RS42410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_244933926.1"
                     /transl_table=11
                     /translation="MAALAVVRDLREHWAPASAEELEQFETDALSGFVLARASAGLADG
                     TIRGDVGHLDQIRTWFGRPLWDMEPADADAYFGKVLRGSPSGTRLARSQALTTYFMFLE
                     LRHKVELHRITGRAIECPIDEMNRPRGAKDAQLRIPPSEPELGRLFTGWGGELANCRKF
                     APTARNYTASKLMSQVGLRVSEACKLDLDDIKWDLGRFGKLHVRYGRAPAVRGRASGWC
                     R"
ORIGIN
        1 tgactcctag gtctgactgg cagccgacaa tgcctccaac ggcgacggct gcttgctgcc
       61 cctgacttcg cttagcctaa cctaactttt ggaaatattg atccattcat taccaaacat
      121 cgcgacggag gggcttgcgt cggccacggg gtggccggaa tgcgccgggt gtgtggcgct
      181 cgcgacggac caacggccgg tgtcagaggt ctttgtgaag ccctgtgcgt gcgttccggc
      241 ctcagtcccc gtactcgcgc ggtcgctcag ggggccggcc gcggcgccac cgaccgggtc
      301 ggccacctgc gcggcggcgg ggccggccgg tcggcggcct gtcgtaactg tccggcaggc
      361 aaagggagtt cggtgagcgc ttcaggggcg cgcccggctg ttcaggagct agagggagcg
      421 tctcccgcac cgttccactc cgccccgccg cgtgcgggaa cggtgtgtac gggacggagg
      481 tccggacgtt tcgcggtgcg cccgtcgccg gaggactggc cgcgcaggcg cctgccgagc
      541 cagggcccga ggaaggaggc ggcccaccgc agttcgtccg ccgccgtgcg ccatccggtg
      601 ggggtggcgg gacgcgggcc ggccaccggt cgggtccacg aatcgtcgct gcccggcagg
      661 tccagggcgt gggcgacggc ggcggcgatc cgctcgtggc cgagtgggct cgcgtgcagc
      721 cggtcggggc tccagaggcg gggatcggtg accacggggt ggtgcgcggt ctcggcgagg
      781 gtgacgccgt gccggtgcgc ggcctgccgg atgcggtggt tcagggcgct gatgcgggag
      841 ctgaccgggc gggcgagcgg ggtgatccgc gccatgtcgg ggaaggtgag cgtggcgacg
      901 cgggcgccct gcgcggtgag cgccgcgaac atcgcctcca gctcgccggc gacctcgtcg
      961 gcgtcgaacc gcggccgcag cagatcgttg actcccgcga cgacggtggc caggtcgggg
     1021 cggagggcga gggcggctgc gagctgctct tcccggacct gccgggcgag acggccgcgt
     1081 acggccagat tggcgtaccg gacgccggag ttgtggagcg cgagctgctc ggcgagccgg
     1141 tcggcccacc cccgcagccc cacggtgtcg tcgccgtcgc cgaggccctc ggtctggctg
     1201 tcgcccaggg cgacgaaccg cagagggcta tcgccgggca cgggccgcct gcctctcccg
     1261 caggacctcc gcggtgcgcc ggcaccagtc ccggttgctc cgctcgaagt ccagaccacg
     1321 ccggcaggtc agatagggcc cgatccgctc gccgtgccgc aggaactcct cctcgtcgcg
     1381 gtcgccgcgc atcttccgca gcagtacgtc gaacagctcg gccttggcct cggcgaagac
     1441 ggcccgctcg gtgagctggg cgaccagcac atcggtgtcg aggtggtcgg cggcctggac
     1501 cttgacgaac aggtcgtcac ggatgaagga gggcttggcg gtggccgtcg cgaactcgtc
     1561 cagctcggcc agccccgcat cggtgacctg gaacaggcgc ttgttgggcc gggtgtcctg
     1621 aaccacttcc cgcccggcga ccagcccttc cttctccagc ttggccagct cggcgtacag
     1681 ctgctgcggc agtgcgtgcc agaagttcgc cacacccgtg tcgaacgcct tggccagctg
     1741 gtacccgctc aactcctcgt cgagaagcgc cgccagcacg gcatgacgca gcgccatcgg
     1801 cccgccccct ctcacctctg tccacggaac ccgcctcatg atagtactca tgaatctgac
     1861 tagtcacatt catgactatc aactgtcaat cactgtcgag gagtctcaat gatgaagtca
     1921 agccgcctgc gtgaccggcg gggcggaggt gaagagccgc ccgtcacgca gcagggccca
     1981 cagcacattc gcgcgtcggc gggccagggc gatgacggcc tggacgtgtt tgcagccctc
     2041 tgctcgcttc ttgaggtaga agtcccggtt cgggccttcg cggatgatgc tggtctgcgc
     2101 ggacatgtag aacactcgtc gcaggcggcg gctgtagcgt ttgggccggt gcaagttgcc
     2161 ggtgcgccag ccggagtcac gcgggaccgg caccagcccg gccgccgacg cgagtgtgcg
     2221 acatcccgtg agttcccctg agccccgctg agtccctggc cctgtggcca gtgggttctt
     2281 cctcctttgt gtgctctgtg gccttgtgac gtaacttcgg gattcttgaa gcgttctcat
     2341 ctcgtccgac cgatccgcag tcgggctgaa ggtgaggagg ctcgggttgg cggcgctggc
     2401 ggtcgtacgg gatctgcgtg agcactgggc gcccgcgtcg gccgaggagc tggagcagtt
     2461 cgagaccgac gcgctgtccg ggttcgtcct cgcccgtgcc tcggcaggac tggcggacgg
     2521 caccatccgc ggggacgtcg ggcacctgga ccagatcagg acctggttcg gccgacctct
     2581 gtgggacatg gaacccgctg acgccgacgc gtacttcggg aaggtgctgc ggggctcgcc
     2641 gagcggcacc cgcctcgccc ggtcgcaggc gctgaccacg tacttcatgt tcctggagct
     2701 gcggcacaag gtcgagctcc accggatcac cggccgggct atcgagtgcc cgatcgacga
     2761 gatgaaccgt ccgcgcgggg ccaaggacgc ccagctgcgg atcccgccga gcgagccgga
     2821 gctcgggagg ctattcaccg gctggggcgg cgagctggcc aactgccgaa agttcgcccc
     2881 gaccgcccgg aactacaccg cctcgaagct gatgtcccag gtcggtctgc gggtgagcga
     2941 ggcatgcaag ctcgacctgg acgacatcaa gtgggacctg ggccgcttcg gcaagctcca
     3001 tgtccgctat ggaagggcgc ccgcggttcg gggccgcgcg agcggatggt gccgctgatc
     3061 aacggcgccg accgcacgct gcggtggttc atcgaagacg tctggggcca gttcgacgac
     3121 gaccacaccc gccccggtgc cccgctgttc ccctccgagc gaaagaacac cgacggttct
     3181 tcacgccggg tcggcgacga tgccctgcgc ggcggcctca aggacgcggc caagctgcat
     3241 ctgccggggt ggggcgagag gctgaccccg catgtcctgc ggcacttctg cgcgtcccag
     3301 ctctatggaa acgggttgga cttgctcgca atccaggagg ttttggggca ttcctggatc
     3361 gctacgacca tgcggtatat ccacgtccag cagacccggg tcgaggacgc ctgggtcgcc
     3421 gggatggaac gggccgcgaa gcggctggaa ggactggtcc gatgaggtgg aacctgcggc
     3481 tgaccgcggc gaacaagggt atctggaagg cgtccgagct ccaacggagc ctggccgagc
     3541 acggattggt gatctcggcg ggcaagatgt ccgggctgtg gtccggtcag ccggtctccc
     3601 tcaagctcga cgacctcgac gtcatctgcg tcgtcctcgg ctgcgaggtc ggcgacctga
     3661 tgatccccga accggacaag gtccgccgcc ccggcgagga gaccgggcag caggccgccg
     3721 tcgcatccgg ctcggccccg gcggtggtcc ctcgccgacg ggacggccgg tcccttcccc
     3781 cggcgtgacc catggacccg agctcctgcc cggaatgcct gtcctggggt cgcttctttg
     3841 aaccgcggtg ttcgacgtgt tccggattcg cccgtcgctg gaaggcaggc gagtgcgccg
     3901 gctgcagacg ccaagtgccc ctgcgggagg agtactgccg actgtgctgg acccaggcac
     3961 ggatggaggc tgacgcggtc ggcgacaaac cggagtcctt cctgccgcac ctgcgtcacc
     4021 agcagctgtt cttctatggc atgacagcga cctgggaccg acggcccaag tcggcaccgg
     4081 tcaaacacgg ccgccggggt cgcccacgtc ggccggagcc ggccccggcg cctccaccgg
     4141 ccgcagtctc ctgccaacca gcgttgttcg aggtccgccg ggctttcccc gggcggaagg
     4201 ccgccgacga gtacgcgcag tacggcaacc cctggctggc ctgggcccgc cacagtgccc
     4261 accggctcgg cgaggcccga ggctggcccc gccagacgcg gctgaacgtc gatcaggccc
     4321 taatcctcgt actggccggc cacgccgacg gtgacacggt ccgctactcg gagatcttcc
     4381 cggtgctgcg ggcacgcggc ctgagcgtcg agcgcaccac tgaagtactc gaccacatcg
     4441 gtgtcttcct cgacgaccgc ccttcgtcgt tcgagcagtg gctggaggcc aagctcgacg
     4501 gcctcgccac tggagttgcc cgtgatgtcg gggagtgggc ccggctgctg cacgacggcg
     4561 gaccccgttc ccgggcccgg gacgttgcga cggtctggaa ctacctcaac cggatccggc
     4621 ccgtgctgct ggagtggtcg aaccgctacg accacctgcg cgaagtcacc cgcgacgacg
     4681 tgctcacctg cctcgacacc gtgcagggcg cacatcgcca ggcaaccatc gtcgccctgc
     4741 ggtccttgtt ccggcaggcc aagaagaacg gcaccatctt caagaacccc accagccgca
     4801 tccgcgtcgg ccagcgggag gaaggcgtca tccagcccct ggaaccgcat cacgtcaacg
     4861 ggtctgtcgc cgcagtcacc caccccgccg accggctgat cctcgccctc gccgcagtcc
     4921 acgccgcacg gcctgcggca atccgccgcc tccaactcga cgacctcgac atcggcaacc
     4981 ggcgcatgac catcgacgga cacgcccgac ccctggacga cctcacccgc gaagtcgctc
     5041 tggaatggct ggagttccgg cgccggcgtt ggccgaacac cgccaatctg catttgctga
     5101 tcaacaagca gaccgcactg ggaaccggcc ccatcagcaa gagctcggtg gccggtcccg
     5161 cactgcacgg ccagaccgcc actctgcaac ggctccgcat ggaccgccag ctcgaagagg
     5221 ctctggtcca cggccctgat gcactccacc tcgccgaggt cttcggcctc agcgaaaaga
     5281 ccgcgatccg atacgcgaac tccgcccgcg ctctcctgga gcggcccctg gagagcgacc
     5341 ctgcggcttc accgcgaacc cacgggtcca ccccctaaca tcaaggcatc ggaccctcgg
     5401 gttcccgctg aagtaccttc agttttcgcg aacccgcagg ggtctcgggg tagcgccgag
     5461 gtaagcccaa aaggggccat gggatgatct tgaagttgtg agggcctggc ccgtcacccg
     5521 ttcggctcag tgtcgttggt ggtgatgttg actgtcgtct ggggcctggg gtgggttgtg
     5581 acctcgatcg aacggaccgc gtatccgcgg ttcaagcggc tgatcaccgc gcatgagctg
     5641 catctgttct tctcgccgac tcgcgatgag ctggagtggg ccgccgaccg tacggacagc
     5701 gatgagcatc tgctggccct gctgctgacg ctgaagtcgt atcagcgcat ggggtgcttc
     5761 ccgaaggtgg aggacatccc ggaggcggtg gcggagttcg tgcggcgggc ggtggagctg
     5821 ccggagggca cgctgccggt gtaccgggcg gcgaagacca tgaagaacca ccggggcctg
     5881 gtacggcagc gggttggcgt ggcctacgac cagggcaagg cccggcggat cgccgaggcg
     5941 tcgatccgca aggaggccgc ggcgaagaac cggccggcgg acctgatcaa catcgcgctg
     6001 gagaaggtgg tggaggcggg gctggagctg ccggcgttct ccaccttcga cgcgatggcc
     6061 tcgacgctgc gcagggaggt gaacgccgag atctgcgcgg gtatccacga gcggatgagc
     6121 gcgccggagc gggcggggct gctgcggctg ctggaggagc gcatgagcga cggcacgacg
     6181 ctgttcaacc ggctcaagaa gcccgcccag ggcccgacct ggtcacactt caagaacctg
     6241 gccaaccggc gggaatggtt ggacgagctc ggcgacacgg atgtgtggat ggagggtgtg
     6301 gccgcgggga agatcaccga cttcgccggg gaggcggacg cggccgacgt ggcggagctg
     6361 cgggactaca ggcccgtcaa gcgcctcgcg ctggtggcgt gcctggcgca caaggcgagg
     6421 atgcgggtgc gggacgacct ggcgacgatg ttctgcaagc gcgtggcgat gaagatcaag
     6481 aaggccaagg cggagctgga ggagatccgg ctcgcggagc gggaaatcac cgaggccctg
     6541 atcgggaact accgcacggt gctcaagcac atcgacgagg gcggcccggc tcaggaggcg
     6601 ctggagaggg ccgcggccat gaccgccgag gcccgccagg ctctggaggg cctggacgag
     6661 gaggcgtcgg tggacgaggt cgcgaagcgg ctggaggggc gggtttcccc ggcagtgctc
     6721 gccctggtga aggcccagat ggtgcaggcc ggcgggttcg gagcggtcac gcgggcggtg
     6781 gagggcttcg gcgggttcgc caagcagtac gagcagatcg agaaggtctc cgcccaccac
     6841 ggcaacttct gggaggtgct gctgtatggg cagttcggcc gggaccgggc ggtgatgttc
     6901 gacctggccg gggccgagaa gctggagttc accgcgacca gcgaggattt ccgggtactg
     6961 gacgcgctcg cgcacgccca gcggcaccaa gcggcccgcg gcgagtacat caccgcgttc
     7021 aacgaagagg gcaaggaggt cgacatctcc ttcgccaccc agaactggcg caaggccgtc
     7081 ctcgacaaga cccggcccgg tcagttcgtc cgcaagcact tcgaggcgat ggtcttcacc
     7141 gccctcgccg aggaactgcg caccggcgac gtggcggtgg tcggctcgga ggagtacgcc
     7201 gactggtccg agcagctgct ggcctgggag gccgtgcagg agaagctggg gtcctacctg
     7261 gtggaagtcg gcctcgccga gccgggcgag agcgccgagt tcgacgcgaa gttcttccgc
     7321 cggcagctgg aggacaagct gcggaacgct gccgctgcgg cggacgccgg gtacccggag
     7381 aacgagggcc tggtcatcga cccggagacg ggcatcccgt cgctgaaggc gttcagggct
     7441 gacggccagc ggccctccgc caagcgtctg gagcaggaga tcaaggcgag gatgccggag
     7501 cgttccctga tggggatcgt ggcgaggacc gcgtactggg tggagtggtg gcgccgcttc
     7561 ggcccgccgt ccggcaacga gcccaagctc accgacccct tgggccgcta cgtgatcacg
     7621 accttcgtca agggcaccaa catgggcccc tacgaggccg cccggcacat ccccggcgtg
     7681 agcgggcacg aactgtccta cgtcgccaac cggcacttct cgatcgtgct gctgaacgag
     7741 gcgatctccg acctggtcaa cgcgcacgca cgcctcgaca tctcgcaggc gtggggagat
     7801 gggaccgcgg tcgcggcgga cggcacccac atggacacct atctcgacaa cctgctctcc
     7861 gagacgagcg tcaggtacgg caagccgggc ggcatcgcct accaccacgt ctcggacacc
     7921 tacatcgcgc tgttcacgca cttcatcccg tgcggcgtgt gggaggccgt ctacatcatc
     7981 gagggcctgc tgaaaaacac gagcgaggtg aagcccacca cggtgcacgc ggatacgcag
     8041 ggccagagct tccctgtctt tgcgctcgcc cacctgctgg gcttcgactt gatgcccagg
     8101 atcaggaact ggaaggaact gaccttctac cggccctcca agcagagcga gtacgtgcac
     8161 atcgacgccc tgttcggcga gccgagcaag aacgtcatcg acttcgacct gatcgagtcc
     8221 cagttccgcc acctgatgcg cgtggccgtc tccgtgcgtg agggcaccat ctcctcctcc
     8281 acactgctca agcgcctgcg ctccgggtcg cggaagaacg ccacctacgc cgcgttccgc
     8341 gaggtcggcc gcgtgatccg caccgtccag ctgctgcgct acctctcgga cgcgccgctt
     8401 cgccggcggg tgaccgcggc gaccaacaag gtcgagtcgt tcaaccggtt ctcccagtgg
     8461 atcggcttcg gcaaccgcgg tgtcatcgcc gacaacgacc ccatcgagca ggagaaggcg
     8521 atgaaattca acgccttgtt gaccaacgcg gtgatcttcc acaacgccct ggacatcgcg
     8581 gagatcgtgc ggcagctgct ggacgaggga tgggagatcg atccggagga cctggcgcac
     8641 atctcgccgt acctgaccga gcacatcaac cggttcggtg agtactccac gcacgaactc
     8701 ggcatccagc ccgacgcgta cgacccgaaa ctcgacgtcg acttcacccc gctgcgcgag
     8761 caggacctca ccaccgccgg cctcggccag gccgcctgag caggccgcgg ccgggtcagc
     8821 gtcacgggtg ctggctggcg acggggtgga gacgacattg cccgggacgc tcggcgtccc
     8881 gggcaatatg cgtgagcggc agcggcaagg ctaccgggaa agccgcaggt cccagccttc
     8941 gccggtgcgg accagggccg gggtgtaggt ggagggggcg gggcggccgg cctcttccca
     9001 ctgccccagc caggtgcgga ggacggtcag ggacggggag tcgggggcgt cggcgaggat
     9061 cgtgccgtcc tgctggatga cggcggccgt cgtggtggtg gtgtggccga tcgcccacag
     9121 atccgggctg agcccggcca tggtgagccg gtggtcgccg cgcgtggcgg cgaacgtccg
     9181 ccaggacggc aggtcgatct ccgcgcccgc gtacggctcg gtgtgcgcgt tcttcagcag
     9241 ccgctccagt gcggtgcggg caccggtgtg cagatggtcg tcctcgctcc gccaggcgat
     9301 cgagatccag gagggggcgg ggatgcggtt ctcccagtcc acccagcggc cgggcaggtc
     9361 gaggtcggtc ttgggcgagc tggtcgcctc gatgtacccg ccggtgaaca cctcctcgac
     9421 gaccggctcg ccgccggtga cgcggatctt ggcgacgacg gtcatgttgg gcacggccgc
     9481 gatcggcagc ggggcgacga tgaggccgcc gtcggcgacc tggtccaccc acgccttcgg
     9541 cagcagcggc ggggtgcacc aggccaccat ccggtcgtag ggggcccgct cggggaagcc
     9601 tccggtgccg tcggcggcgt ggcagcggac atggtccacg ccgcgctggt ggtggatgag
     9661 gcccgcccag cgggtcaggt aggtgtcgat gtcgaggctg gtgacgtgcc cggtggggcc
     9721 gacgagctcg gcgagcaggg cgccggagta gccggagccg gtgccgaact ccacgacgtt
     9781 catgcccgac tcgacgccga gggtggtcag ttcgcggtgg atgacggccg ggttggagcg
     9841 gtgcggggtg gcgccgcggc cttcgtggtg ggtgtagtgg cgttcgggga cggtctcggc
     9901 ggccagggcg acggcggaca tcggctcact ccttcgaggg gtacgcgtat tcggtcaact
     9961 gctccgggcg ggtgaaggac acggcgcccg gcaggggcgg tcagatcgtc agtgcggtgc
    10021 ggtggtgcca gcctccagcg gtgtattcgc cgaccggtcc gtggccgggc agttcggccc
    10081 aggcgtggta ctcgaccggc ggcggcgcga accgcgcccc caggcaccag tccaggcgcc
    10141 gcccgagcag agccgcggcg agcacggcgc cgagcgaggt ttccatgcag gcggcgcggc
    10201 cgggccacag gtggccggtg tgccggaccg cttcgaccag cgccccggcc cgctccggcg
    10261 ccagcggccg gcggccgacc cgccgtgccc agcggaccgt acggacggtg tggcggaacg
    10321 gcagtcgcag cagcaccagg gcgagcgcga gaccggcggc agccgcgcat cgctcgggga
    10381 acgtgccggt gcggacggtg gagtacgcct ccatgctcgt caccgccacc acccccacca
    10441 gcgacgacgg gatgccggtc cggcggcgcc gaggccctgc gcggtcagcg cgtcggcgac
    10501 cgtacggaca tcggcgtcgg cctgcccggc ggggatgccg tagcgctccg cgtactgccc
    10561 ggcggcctcc tcctcggtgg tgcccgcgag gaggagcatc acggcggcgg acgcggtcgg
    10621 cgtcaggtgc gtccagcggc cggtgcgctc gtccaggatc gcgccgccct cgtcggtgag
    10681 gaccgggtgg gcactctcac gcagctgcca cacgggagtt cacctcccac cacgtcgggg
    10741 cggtggtgtc gagctgccgg agccagacct cggcggcgac cgcgaggtgc agggcgccct
    10801 gggccgtggg ctgtccggcc gcggcccgct gaagcatccg tgccaccggc tgctcggtga
    10861 ccagcccggc ggcggccagc cgcgaggacg cgccgaggag atcgagcagg acgggggcgt
    10921 tctcccgcag gcccgcgtag gcgagggcgt tgaagccgcc cttcgtggtc cggttgagca
    10981 cgaagtcggg cagcaccccc gttccggtga acgccgtggt cagcagcggt ttgtagcggc
    11041 cgggggcgcc gcgctggtcg gcggggacgg ccaggcaggc ccggatcacc tcgttgtcga
    11101 gatacggggc gaccaggtcg acgccgtact cggcggacgc gatctgccgc cagccggtgg
    11161 tgtcggcgcc gagacgggcc aggtcctgcc agtccgacca cgcggcgagg cgtgcgggag
    11221 cgtcgtgcag ctggccggcg gcacggtcga gggcggcggc gagctggtgg cggacgtcgg
    11281 ggctcatcca gtcggcggtg gccagcagcg gcgtccacgc caccggccgt accgcctgcg
    11341 gcacccactc ccggaccggg ccgcgcagtt cggcggccgt ctgccgccag gcgccggcca
    11401 ggccggtacg ggaggccggg cgggaccggc cgagcaccga ccaggcggag gtgtgccgca
    11461 gtcgggcatg gccgagcgcg tgagaccagg cccggcggtg ctgccgctcg cgcagcaggt
    11521 cggcgaggta ggaggagggg gcggacagca ccgcgtcccc ggccgaaccg gtcaagtgca
    11581 ggccgggcac gggatggtgg gcggcgacgg tgtccagcac ggcccgcttg atcgacgccg
    11641 tcaccgcgta cgcgttgggc gcatcggtca ccggcaggcg ggacaggtcg tccaggccgt
    11701 cgtagtagac ggtgttcgcc gtgccgggca ccgggtggtg ggtcaggttc ggcaccgtcg
    11761 cggcggtgcg ggtcgcgtac gggaggtcgt cgtcgcgtag gcgttcgtcg gcgaacgtca
    11821 ccgcggtgac cggcccgcgc gtcgcggcga ggcaggcgag cgtcgtggag tcgagtccgg
    11881 ccaggtcggc gctgactggc cgctcgtcga gccgggtggc gacggcttcg ctgagcgcgg
    11941 cccgtaccgt cgccgcggcg acgggcagat ccacgcgtcc gtactcggcc ggctcgaacc
    12001 gcaccgtacg ggcgcctttg tcgtcgacca gcagcagatg gccgccgggt acccgctcca
    12061 cgcatcgcag gaggctgtgc tgccgaagga cgtccggctg ggccagggcg aggtgcgcgg
    12121 cgagcgcggt ggggtcgacc ggtgccccgt cgagggcggc cagtgccagc gcggatgtcg
    12181 cccaccacac caccccgccg tggcttcgcc agtacaccgg gtgctgcccg gccaggtcgc
    12241 cgatcacggc cagcgtcgcc ccgttgcggg cgatggccag gtacgagccg ggccatcggg
    12301 tcagctcccg ccaccgcccg gcccgaacgg cgggcagtcg cgcggcgagc tggtcgtcgt
    12361 cggccccgca gtccccgatc acggccagcg acaccggccc ctgactcacg ctcagcaccc
    12421 gcctggtggg ccaacccgcc gtccatgccg cctcgacgcc gggcaccggg tgcccacccc
    12481 ggggccgtct ggcctcctct gcgcttccgt accgtcccgc gctccaccgc atcgccgccg
    12541 tctccttcag ccgtcgtcgt gcctggtcag gaaccgaaaa gagcgccggg cccgcccgtc
    12601 tgtgccccag cacaggtatg gcgggcccgg cgccctgggc cgggccggac agggcggcgt
    12661 gcaccccgtc cggcccggca gacccgaagg tcaggcgttc ttgtactggg tgtcgtcggc
    12721 ggtgtcgaag ttctgggtgc ccagcgtcac ctcgacgacg tcgccggcgt ccagcacgat
    12781 gggcgcctgg taggccgggg tctgcgtggt gtgctccatg tcggaacctc cttcgtcttc
    12841 cgtccctggc gtccgggagc ggacgcgcag tgaacggcgg tgcccgtccc ggcagttcgg
    12901 cggccccgga atccggtccg ctgtgctgcc gggcatgacc aacagtcaac cggcagtgac
    12961 ccttcgtcgg tacggttggg aaggacggat gggtatacga ggtatacggg ggcggtcatg
    13021 acccagcgct taccgaacgc caggctgcgg gacgccgtcg cggaatcggg gtggacgtac
    13081 gccgccctcg cccacgcggt ccgccaggtc gccgcggaga acggcgcctc gctgcggacg
    13141 aacaagtcga cggtggacca ctggatcgcc ggggcgatgc cctcggggca gaccggccgc
    13201 tacctgacga tcgccctctc ccgccgcctg ggacgcacgt tgaccccgga ggatctgggc
    13261 ctgccggtcc cggccggctg ggagaatgac agcatcggac tgtccatcgg agacgacccg
    13321 ctggaggctc tgatgccgat ctggaggggt gacttggacc gtcgacgttt cctgtccggc
    13381 gccgcgtact cggtggccgc cgccgtcctg ccgctggagc acgtcaccga tatcgcctcc
    13441 cgcgcggcca aggcccgcac cggcgcgatc gtcgggcacg cggacgtcgc cgcggtgcgc
    13501 gacatggtcg cgatgttcgc agtgatggac gaacgccacg gcggccagca cggccgatcc
    13561 gcgctcgtgc agtacctgat gtcggacgtc gcggccctgt gccgggggcg gttcagctcc
    13621 gaggacgacc accggcacat gctgtccgcc gccgccgtcg gtgttcacca ggccggttgg
    13681 cgggcgtatg acggcgggga acagggcctc gcgcagaggt attacctcca gtcgtacgcc
    13741 ctcgcccacg agtcggggat caccggtcac gacgcgttcg tcatgaggac catgtcccag
    13801 cagggcatga agctgcaccg gcccgagcac tgcctggccc tggccgcgag cgccgtcgac
    13861 aaggtccgcg ggcgggtcga cgcccagacc gaggcgctgt tcgccgtcac ccacgcgcac
    13921 ggcctcgcca aggcgggcca gcggaccgag gccgtgcggg aggtcgagcg ggccagcacc
    13981 gctcttggct cggcgaaagg tgacgaggtg ccgttctggg cgctgtcgtg ggggccaccg
    14041 gccgccaccg ttcacagccg gacagcgaag gtcttcgaga cgctcgggga ccggcgccgg
    14101 gccgcggcga tgtacggggc ggcggcgacg agccggccgc cgggcaccta cgcgcggatc
    14161 gtcgccctcg acctggtcgc ccaggccgag atgcaggccg ccgagggcag catcgagcag
    14221 gcgtgcgcca cctggggccg ggccatcgac cacatggacg gcgtgcagtc cgggcggacc
    14281 cgcaaggccg tgggcaacat gcgccgtgac ctgtcccgct tccgcacccg cggcctgcga
    14341 tgcgccaccg aactcgacga gcgcgcccgc gacttcctca gcgaccgccg ctgaccccac
    14401 gccccgggcc gggtacacgg cggacccggc ccggttccag accgctgttg ccggggcccg
    14461 gtacggtgac cgagccccgg cctacgactc ctgacctgga agaacgcccg tgaactatca
    14521 cccccagtac cgagcgaagg gcgcccctgt cctcggcgtt ccccatggca ccccgggccc
    14581 gttcggcgtc caccgccccg acgaggacac ggacgagcag ccgcaggaca aatacgcggc
    14641 tgccgtcccc gctccgcgcg acggacgcga gcggtgagcg gaatctggcg gcaggtcctg
    14701 gccgcctaca ccaccggcca gcacgacgaa cgcgaccgcg aacagcttct cgccctgggc
    14761 gccgcggaac tcgcccacgc ccgcagcgaa gaggaccaac ccgcgaccgc cgaggacgtc
    14821 cagcgcatcg cgctccacga attcggcctt ctcctcggcg tcacccaggc ccgcaccgcg
    14881 ctgcgggaac gccgtacccg ccacgggtga ccgcggccgg attcgcgcgt tagaactgcg
    14941 tgaccacgat gacgccgcag cccgccccgg tctccggccg tacggcaccg gctccggcac
    15001 cggcttccgc cccgacggaa gagccggtct tcgcggcact ggccgcccgc tgggcggcgg
    15061 cggggcgtgt cgtacccggt caggtggatc gggagtgggc catgctggca ggcagctgcc
    15121 cgtggcccct gcggtagaga ccagcgtggt gcggcggctc ccccgtcccc gcatccgctg
    15181 accggccggc agcctcgacg cctgcccggc cacccgaggc tgccggaccg gccggccttg
    15241 ttgggccccc ttccggcccg gcagcctcca cgtctgcgaa ccggaaccgt ccaggacgtg
    15301 gtgtcgttga ccgggcgtgg gtgggtacac ctgtgcgctc cccgacgatg aacgcctgga
    15361 ccgacagccg agctcgtgac ggaagcccgg gtgagcggcc catcgccgca tcgtcggggc
    15421 cgtgctcagt aggaacggag caggaaaccg gtgttgacgt cagaagtttg gacgcgggtg
    15481 atgtcagccg gcgggcagct cagggcgcgt cgagcagggc gccgatcagc ttgtgggccg
    15541 ccgccttggt cagccgcttc gaggccgtgg cggtccgctc ccggggggcc cgcggcttga
    15601 tgtcggtgcc cttgacggcc ttgacgtact cggcgtcgaa ccgctccttg ccggccttct
    15661 ccacgaggcg ggtgaggtac ttcaactgcg caggcgtgat cggggtcttc tgcgccgcgg
    15721 ctttccgctt cgcactctcc tcgcgaatcc gcccgtagta ctcgtcgttg gccgccttgc
    15781 gcttcgcctc ggactccggg ctgcggcagg tgatgtgcac gccctcgtgc cagctctggg
    15841 tgccgggctt gccggtgacc gcctcccaca gcgcgttggc ggtcagcgcc gactcgtcca
    15901 cgccctccgt caggccgggg cccaccagac cgtagtagcc ggtcttgccc cggggcagga
    15961 cggtgaaccc ggccgggatg gcgtgcgcgg tgagccagtc ctgcccgcaa ccgcagtgat
    16021 aggcgtggta gcggctccac ttgctctcca gcggctcgta cacgagacgg tcgccgtagt
    16081 acttcgtatc cctcgcgaat cccgacaccg ccgcagtttc ccattgcgtc cggtcgtgga
    16141 acagtggccg tcacccctgc ggtggttggg gaacaccgga acgaatatcg gcgctccggg
    16201 cagccgtccg gcagcctcgg gccatgggtg tcacgcacgg tcattctcat aaatgaccat
    16261 ctgtgagagt tctgagaacg gcccccgggt gatcacattt gcaggtcgcc gctcgcaaaa
    16321 gtcctctcga aacccgcacg ttgtgcgagg cacttctgag agactgcctc catggatttg
    16381 acgcccgatc aggccgcact tgcggtagaa cgtcacgact gcccgaactg tgacgcgccc
    16441 gccggcagcg cctgccgcac ccggggcggg aagaccgccg cgaagtacca caccccgcgc
    16501 ttcgtcctcg tccccgccct ccgcgaggaa ctggagatcc ccgtccccgc cgaccgcgcc
    16561 cccggccgcg cgtggaagca gggcccggcg ctcgccgtcg tgcccgcgcc ccgcaccgag
    16621 cggccggtga ggatcgggta cgcccgtacg tcgaccgccc gccaggaact ggcgagccag
    16681 ctcgaagccc tccaccgcgc ggagtgccac aaggtcttca aggaacagat cagcacccgc
    16741 atcaaagtgc ggcccgagct ggagaaggca ctcgcgctgg cccaccagtt caaggaggcc
    16801 gcacccgaga cgccggtcat cttcaccgtc cacgagctca agcgcctcgc gcgcaacgcc
    16861 gccgagctga tgacgctgtc cgccgagctc caggccggcg gcatccagct cgaactcctc
    16921 accggcccgc tcaccgggat ctacgacccc aacggcatgg gcgcgatgtt cttcgccgtg
    16981 ctcgccgtgg ccgggcagat cgagcgcaac tacatccggg agaagaccct cgaagggcag
    17041 gtcatcgccg cgtccaaggg caaccacggc ggacggccga aggtcatcga cgaagacatg
    17101 ctgaccttcg ccgtcgcgct gaaagacaag ggcgtccctg tcccggagat cgcgaagaag
    17161 ctcatcatca aggtcgggaa gaacgcgggc aagtccccct ccgtcgcctc gctctaccgg
    17221 gccctggccg aagtcgaaca gcaggaaccg gccgctgagc cccgggtgat cgagcagccc
    17281 cgccccaggc ccgcccggat cacgggcccc gacagcgaaa ccgacccgga gctgatgcgc
    17341 cgcctggaac agcaggtcct cggccaaaga agcaaacgat gacgctgtgg cggcagatcc
    17401 tggccgcgct ctgatgttcc atccagggac gaccgtccag tacctcgccc tctccgagca
    17461 ctggggtgcg tacggcatcg tcgccggtgg cgtcggcgac ggcgcgacct acaccatcga
    17521 ccttctcccg ccccgcaccg gcaccgcggt ctgggggcac accagcgtgg tccgcgtctt
    17581 cgacgcccct gccgccgccg aaaccctgtc gcccatccac ccggccggaa cggtcccgat
    17641 ccccggcctt cgccccgtcc tgcgtcggcg gcgcccgcct ctgccccgcc ccgtcgtcgg
    17701 ttccctcgcc gaggccgttg ccgtggccga ctggcgcccg gagtacagcc cctacggtga
    17761 ccccgacagc tggacacccg tcggcgaagg cgcccatcgg gctgtcatcc tcaaccccgc
    17821 ccggaccacc gtgtacaaga tcgagacaca ggccggccgc aaccaacgcg aacaccgcac
    17881 cctgggcggc ctgcgtcacc aggggtactc ccacgccccg cccaccacgc tgtggaccgt
    17941 gcccggcccc gcccaccact ccgtggttct ggccatgccg tacctgccga acgacggcac
    18001 tgcatcgcgc accccgtacc cccgtgccgg cgtgaccgat ctcaacccag ccaacgtcac
    18061 cgtctgccgc agccagtact ggctgatcga cgccagcggc ctttgactgg cgggcaggga
    18121 ctgaggccgg tggcgcgcgg acgacgatgg gcgtagaccg gaggtatggc tggtacgcgg
    18181 acctgcgcga tgtgccacga gctgctgcct tcgggttcgg cgccgcggcg ccggtactgc
    18241 tcgaccgcgt gcaagtcggc atggttccgg caataccgcc gcaacgcccg cgccctcgac
    18301 ctcatggccg cccacacgat gggacgcggg cccacctgcc cgacgtgcgg ccaccgcctc
    18361 gcccccggct acttcacccg ctctgaccag gctttttgcg gcgggcgctg ccgtacggcc
    18421 gcgtggcggg aacgcgcgcg gaaggggtcg gcgaaggtgg ccgtgtgacg gctacgcgat
    18481 ccggtgggcc gacccggcgc cgggtcggcc gaacgggagg accttgaagg catggccagc
    18541 ctgttgcggg aagcggcggc gctccttcga cgtcacgcgg ccgaggccac ggagttcccc
    18601 gacgagcggt ggatggtgga ccaggacgag acgggcgggc tggtcctcgt cgcattcacg
    18661 ccggaggacg tcgaaccgga cggcaccgtg agcagcggca tcctcgcctc gttcgcctac
    18721 cccgacaacg cggagcgggc gacgcacgcg cgggccctag cagcggcgtc ccacacggca
    18781 gccctggacc cgcaggccgc atggatgctc gccgcctggc tggagaccac ggcatcgttc
    18841 gaggaccggg ccgaagaact cggagacgtc gagggcgcag caccgctcat cgacccggcg
    18901 acccgcttcg ctcgcgccta cgtgcggaac gcggagacct agcacccgcc caagttgggc
    18961 cgttaacgag cgccgatcct ggtgacaagt aacccgcgag tagctttcgg atcgaaggtg
    19021 ccgcgccgat ctcctaccgg ccctccaggt agtcggcggc gcgttcggca gcctcgtcga
    19081 gggacagcct ccgacgggcc gacggccggt ctcgccgacg ctcacggaaa cgggccaccc
    19141 agccccacca cacacgggaa ttctgctcat cactcatcga gcaagatcat cccatggccc
    19201 cttttgggct tacctcggcg ctaccccgag acccctgcgg gttcgcgaaa actgaaggta
    19261 cttcagcggg aacccgaggg tccgatgcct tgatgttagg gggtggaccc gtgggttcgc
    19321 ggtgaagccg cagggtcgct ctccaggggc cgctccagga gagcgcgggc ggagttcgcg
    19381 tatcggatcg cggtcttttc gctgaggccg aagacctcgg cgaggtggag tgcatcaggg
    19441 ccgtggacca gagcctcttc gagctggcgg tccatgcgga gccgttgcag agtggcggtc
    19501 tggccgtgca gtgcgggacc ggccaccgag ctcttgctga tggggccggt tcccagtgcg
    19561 gtctgcttgt tgatcagcaa atgcagattg gcggtgttcg gccaacgccg gcgccggaac
    19621 tccagccatt ccagagcgac ttcgcgggtg aggtcgtcca ggggtcgggc gtgtccgtcg
    19681 atggtcatgc gccggttgcc gatgtcgagg tcgtcgagtt ggaggcggcg gattgccgca
    19741 ggccgtgcgg cgtggactgc ggcgagggcg aggatcagcc ggtcggcggg gtgggtgact
    19801 gcggcgacag acccgttgac gtgatgcggt tccaggggct ggatgacacc ttcctcccgc
    19861 tggccgacgc ggatgcggct ggtggggttc ttgaagatgg tgccgttctt cttggcctgc
    19921 cggaacaagg accgcagggc gacgatggtt gcctggcgat gtgcgccctg cacggtgtcg
    19981 aggcaggtga gcacgtcgtc gcgggtgact tcgcgcaggt ggtcgtagcg gttcgaccac
    20041 tccagcagca cgggccggat ccggttgagg tagttccaga ccgtcgcaac gtcccgggcc
    20101 cgggaacggg gtccgccgtc gtgcagcagc cgggcccact ccccgacatc acgggcaact
    20161 ccagtggcga ggccgtcgag cttggcctcc agccactgct cgaacgacga agggcggtcg
    20221 tcgaggaaga caccgatgtg gtcgagtact tcagtggtgc gctcgacgct caggccgcgt
    20281 gcccgcagca ccgggaagat ctccgagtag cggaccgtgt caccgtcggc gtggccggcc
    20341 agtacgagga ttagggcctg atcgacgttc agccgcgtct ggcggggcca gcctcgggcc
    20401 tcgccgagcc ggtgggcact gtggcgggcc caggccagcc aggggttgcc gtactgcgcg
    20461 tactcgtcgg cggccttccg cccggggaaa gcccggcgga cctcgaacaa cgctggttgg
    20521 caggagactg cggccggtgg aggcgccggg gccggctccg gccgacgtgg gcgaccccgg
    20581 cggccgtgtt tgaccggtgc cgacttgggc cgtcggtccc aggtcgctgt catgccatag
    20641 aagaacagct gctggtgacg caggtgcggc aggaaggact ccggtttgtc gccgaccgcg
    20701 tcagcctcca tccgtgcctg ggtccagcac agtcggcagt actcctcccg caggggcact
    20761 tggcgtctgc agccggcgca ctcgcctgcc ttccagcgac gggcgaatcc ggaacacgtc
    20821 gaacaccgcg gttcaaagaa gcgaccccag gacaggcatt ccgggcagga gctcgggtcc
    20881 atgggtcacg ccgggggaag ggaccggccg tcccgtcggc gagggaccac cgccggggcc
    20941 gagccggatg cgacggcggc ctgctgcccg gtctcctcgc cggggcggcg gaccttgtcc
    21001 ggttcgggga tcatcaggtc gccgacctcg cagccgagga cgacgcagat gacgtcgagg
    21061 tcgtcgagct tgagggagac cggctgaccg gaccacagcc cggacatctt gcccgccgag
    21121 atcaccaatc cgtgctcggc caggctccgt tggagctcgg acgccttcca gatacccttg
    21181 ttcgccgcgg tcagccgcag gttccacctc atcggaccag tccttccagc cgcttcgcgg
    21241 cccgttccat cccggcgacc caggcgtcct cgacccgggt ctgctggacg tggatatacc
    21301 gcatggtcgt agcgatccag gaatgcccca aaacctcctg gattgcgagc aagtccaacc
    21361 cgtttccata gagctgggac gcgcagaagt gccgcaggac atgcggggtc agcctctcgc
    21421 cccaccccgg cagatgcagc ttggccgcgt ccttgaggcc gccgcgcagg gcatcgtcgc
    21481 cgacccggcg tgaagaaccg tcggtgttct ttcgctcgga ggggaacagc ggggcaccgg
    21541 ggcgggtgtg gtcgtcgtcg aactggcccc agacgtcttc gatgaaccac cgcagcgtgc
    21601 ggtcggcgcc gttgatcagc ggcaccatcc gctcgcgcgg ccccgaaccg cgggcgccct
    21661 tccatagcgg acatggagct tgccgaagcg gcccaggtcc cacttgatgt cgtccaggtc
    21721 gagcttgcat gcctcgctca cccgcagacc gacctgggac atcagcttcg aggcggtgta
    21781 gttccgggcg gtcggggcga actttcggca gttggccagc tcgccgcccc agccggtgaa
    21841 tagcctcccg agctccggct cgctcggcgg gatccgcagc tgggcgtcct tggccccgcg
    21901 cggacggttc atctcgtcga tcgggcactc gatagcccgg ccggtgatcc ggtggagctc
    21961 gaccttgtgc cgcagctcca ggaacatgaa gtacgtggtc agcgcctgcg accgggcgag
    22021 gcgggtgccg ctcggcgagc cccgcagcac cttcccgaag tacgcgtcgg cgtcagcggg
    22081 ttccatgtcc cacagaggtc ggccgaacca ggtcctgatc tggtccaggt gcccgacgtc
    22141 cccgcggatg gtgccgtccg ccagtcctgc cgaggcacgg gcgaggacga acccggacag
    22201 cgcgtcggtc tcgaactgct ccagctcctc ggccgacgcg ggcgcccagt gctcacgcag
    22261 atcccgtacg accgccagcg ccgccaaccc gagcctcctc accttcagcc cgactgcgga
    22321 tcggtcggac gagatgagaa cgcttcaaga atcccgaagt tacgtcacaa ggccacagag
    22381 cacacaaagg aggaagaacc cactggccac agggccaggg actcagcggg gctcagggga
    22441 actcacggga tgtcgcacag gtgaccggcg tcggtgtagg cggacaggtc gccggcggac
    22501 acgacgaact cggcaccgag tatcgggccc at
//
