LOCUS       NZ_CP016354            22545 bp    DNA     circular CON 03-MAY-2024
DEFINITION  Prauserella marina strain DSM 45268 plasmid pPmarDSM45268, complete
            sequence.
ACCESSION   NZ_CP016354
VERSION     NZ_CP016354.1
KEYWORDS    RefSeq.
SOURCE      Prauserella marina
  ORGANISM  Prauserella marina
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Prauserella.
REFERENCE   1  (bases 1 to 134495)
  AUTHORS   Ruckert,C., Albersmeier,A., Jiang,C.-L., Jiang,Y., Kalinowski,J.,
            Schneider,O., Winkler,A. and Zotchev,S.B.
  TITLE     Complete genome sequence of Prauserella marina DSM 45268, isolated
            from ocean sediment of the South China Sea
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 134495)
  AUTHORS   Ruckert,C., Albersmeier,A., Jiang,C.-L., Jiang,Y., Kalinowski,J.,
            Winkler,A. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUL-2016) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 33.7x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002240355.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 02:59:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,595
            CDSs (total)                      :: 6,536
            Genes (coding)                    :: 6,497
            CDSs (with protein)               :: 6,497
            Genes (RNA)                       :: 59
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 39
            CDSs (without protein)            :: 39
            Pseudo Genes (ambiguous residues) :: 0 of 39
            Pseudo Genes (frameshifted)       :: 14 of 39
            Pseudo Genes (incomplete)         :: 31 of 39
            Pseudo Genes (internal stop)      :: 1 of 39
            Pseudo Genes (multiple problems)  :: 6 of 39
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:50:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 19934
            Orig. end                         :: 42479
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP016354.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22545
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22545
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22545
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12545](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12545
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            319..513
                     /locus_tag="BAY61_RS33245"
     CDS             319..513
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS33245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_143021476.1"
                     /transl_table=11
                     /translation="MSAVESSGQVTMQNVRAQLSELGERVFRNGEQFIVYRQGKPFFAM
                     VPVPDAEMIRQVKASNKPE"
     misc_feature    complement(535..549)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.52"
                     /tool="antismash"
     gene            649..912
                     /locus_tag="BAY61_RS32020"
                     /old_locus_tag="BAY61_31810"
     CDS             649..912
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31810"
                     /product="hypothetical protein"
                     /protein_id="WP_143021475.1"
                     /transl_table=11
                     /translation="MRAENLFKIAQQQRAAAATLEERTTLSASERLEAAELRSHVAMIY
                     QAIGEAYPIWARLWERLAAAEYAAAGRHELGAYLTEDQVQAA"
     gene            1517..1645
                     /locus_tag="BAY61_RS33870"
     CDS             1517..1645
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS33870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_256328155.1"
                     /transl_table=11
                     /translation="MRKTRLHELVTELVQNTWNSDDADVAQAVLDDENAFGACAIG"
     gene            1906..2481
                     /locus_tag="BAY61_RS32025"
                     /old_locus_tag="BAY61_31815"
     CDS             1906..2481
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31815"
                     /product="hypothetical protein"
                     /protein_id="WP_091810608.1"
                     /transl_table=11
                     /translation="MTTTIHPEQWAGEITAQQALDFYERHSALGLVAMQALLSTSDLSL
                     HAAALTWLAEGAMGEAAVAWQVFNDPVDGNLSNFTPTERAEIIEEHIEGARIVLRLAEA
                     ARAKVEGKQRPCGAWPELEDVAGDVLDLLADPETRSAKEMSALYGDLIQPLLDLGSYPE
                     TVAQLVSVWSEHAENDETLDALESAIRS"
     gene            2810..3115
                     /locus_tag="BAY61_RS32030"
                     /old_locus_tag="BAY61_31820"
     CDS             2810..3115
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31820"
                     /product="hypothetical protein"
                     /protein_id="WP_091810607.1"
                     /transl_table=11
                     /translation="MEWEQAMSSALQRFHHSHQRKRNNTEYWIGQLYATADPAERVAAL
                     GQLLERFELEVASAWLVGDPNRARNLEGQAEAFAVWREVELGVLAPEARRPAPVAR"
     gene            3122..3571
                     /locus_tag="BAY61_RS32035"
                     /old_locus_tag="BAY61_31825"
     CDS             3122..3571
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF041638.1"
                     /locus_tag="BAY61_RS32035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_31825"
                     /product="RRQRL motif-containing zinc-binding protein"
                     /protein_id="WP_091810606.1"
                     /transl_table=11
                     /translation="MGTVTALRVAGDMIQLWDETYWTVDEWVDGLPAWEWGHAPRGLAT
                     RSQLRDLPQPKSIGPQDPYGLLVFRHRKAARRREIAQLYRIDLARDRRAVTPAVLASVE
                     KAMLARRTCRRCGQVQPRCVSTLTRTCWPCMEITGDFGQREQHAA"
     gene            3568..4413
                     /locus_tag="BAY61_RS32040"
                     /old_locus_tag="BAY61_31830"
     CDS             3568..4413
                     /EC_number="2.7.7.65"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /locus_tag="BAY61_RS32040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_31830"
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_091810605.1"
                     /transl_table=11
                     /translation="MNSANPAIAAPRRAGFGIELEENTMSRTFPTTAAVAAAAAAAGWF
                     VTGQRLRRRTSELFTAATELEAASSKLEHSLVDPVSGLLTRVGWDACAAQRAATANAFL
                     LLDLNAFKAINDSLGHLVGDAVLRAVGQRLMTEFGEDALLARPGGDEFTVLTTLTLAAL
                     HEQMERLVEMVTAPVEVPDVGELNIGVSVGLVWLCDLPTWSLDAPDEAEADLWTSVVQE
                     AFAAADIAMYDAKAMHRGWRIYDRDIDPVRPATAIVPGQQRRYRDYGPAALRHQEVVAR
                     "
     gene            4410..4598
                     /locus_tag="BAY61_RS32045"
                     /old_locus_tag="BAY61_31835"
     CDS             4410..4598
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31835"
                     /product="hypothetical protein"
                     /protein_id="WP_091810604.1"
                     /transl_table=11
                     /translation="MTAAPSPAEALLERIRSRYIRPVKVQRNGHLRDDNLLPAIGPTRA
                     GLGGFEIQMLVTCSGAR"
     gene            4715..4921
                     /locus_tag="BAY61_RS32050"
                     /old_locus_tag="BAY61_31840"
     CDS             4715..4921
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31840"
                     /product="hypothetical protein"
                     /protein_id="WP_219341118.1"
                     /transl_table=11
                     /translation="MVVLRHGELELYPRLRRNRDEVLHEFQHLREQGIRSHRDLASALR
                     MTEGALYNMLRRARLAGDPRAPD"
     gene            complement(5460..5708)
                     /locus_tag="BAY61_RS32055"
                     /old_locus_tag="BAY61_31845"
     CDS             complement(5460..5708)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018588533.1"
                     /locus_tag="BAY61_RS32055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_31845"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_091810602.1"
                     /transl_table=11
                     /translation="MAAEQPPLDALRDGDYIKSSRSPQSQPDCVMLYATDGWIGVQDSK
                     EYPDKPKDKRTTLGFTKSEFTAFLEGAKNGEFDHLIA"
     misc_feature    5839..5855
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.93"
                     /tool="antismash"
     gene            complement(5842..6705)
                     /locus_tag="BAY61_RS32060"
                     /old_locus_tag="BAY61_31850"
     CDS             complement(5842..6705)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.3"
                     /locus_tag="BAY61_RS32060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_31850"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_170140330.1"
                     /transl_table=11
                     /translation="MSGDGAVSPTLRRRRLGRQIRDRRTERKMSGTELAKRIGGINQAR
                     LSRVESGKATLTKVQIRKMTEVLELSSEQAELWYELWQEGDQLGWWSEYADVIQEHGEM
                     LAGLESDAAHIRQYIEAFIPLMLTTEEYSHAVVYSSQNTKPSDMARSVEFRMKRQHRLN
                     DPNFRYTVVIAEGALHRHVGGREVLARQLRYLLDTQWTATVEVLIVPFEADVYAAQGMS
                     FEIMEFADPEDPECVFIEFAPTSGFLEKPSELRYYNNMWSVAASKALDVEQSRERIEKV
                     WADLIL"
     misc_feature    6801..6815
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.37"
                     /tool="antismash"
     misc_feature    complement(6806..6815)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     gene            7082..7606
                     /locus_tag="BAY61_RS32065"
                     /old_locus_tag="BAY61_31855"
     CDS             7082..7606
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31855"
                     /product="hypothetical protein"
                     /protein_id="WP_143021474.1"
                     /transl_table=11
                     /translation="MERAVCSTDEAERLAQLAATVDDESWASWMVLPVDKQGATELIVL
                     FARYRRGLVGETQRQIHAIGIVAGRLLAQSLTAACGARLLRAQLEFTAFGEGMPCERCV
                     AKLSVNLPAADEATPELPDLPPDVDVLRTQFGHTSVSPPHRGPAEIPLAGQAKRRPGAV
                     DHAASRARWTP"
     gene            7603..7875
                     /locus_tag="BAY61_RS32070"
                     /old_locus_tag="BAY61_31860"
     CDS             7603..7875
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31860"
                     /product="hypothetical protein"
                     /protein_id="WP_143021473.1"
                     /transl_table=11
                     /translation="MTDSPFPDSPLERRAPGTHLPAQAYTGPIQWPTEDPDNPSPHFAL
                     MTRTLEGLHRYDPPARPRHAAAEDFRGWMQPPPEGKEQFPIDPRM"
     gene            7881..8225
                     /locus_tag="BAY61_RS32075"
                     /old_locus_tag="BAY61_31865"
     CDS             7881..8225
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31865"
                     /product="hypothetical protein"
                     /protein_id="WP_143021472.1"
                     /transl_table=11
                     /translation="MIATLSENELPTLALAATDRPERPAVPVPVGDCGFMAMLREAEPD
                     LAHAQQSHRADGEVLHVWRHAYTHEYVVLIVRDNGRHGVKESGAPLYDRLSQLAGMWLA
                     SESPRRGGAR"
     gene            8222..8620
                     /locus_tag="BAY61_RS32080"
                     /old_locus_tag="BAY61_31870"
     CDS             8222..8620
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31870"
                     /product="hypothetical protein"
                     /protein_id="WP_091810597.1"
                     /transl_table=11
                     /translation="MSTVVAFATSPTPEWSEAEILACVAASTVKPEPAWVPNHLERPQL
                     RAYLAARFPELRYAYAETEPGLEMVHVWLDPASGSWVQMTENLRWGPTIRSDGPRTLLY
                     EDLICAIGDWNRDGRPDVRDVRPGQAGC"
     gene            8620..8844
                     /locus_tag="BAY61_RS32085"
                     /old_locus_tag="BAY61_31875"
     CDS             8620..8844
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31875"
                     /product="hypothetical protein"
                     /protein_id="WP_091810596.1"
                     /transl_table=11
                     /translation="MAWQFGGLVLGAVLVGVVALVILAGIVLWLHTRRARRHQSYVEHE
                     ETPAQQRVRHMHRQDRYLDATQPIPRHPR"
     gene            9003..9776
                     /locus_tag="BAY61_RS32090"
                     /old_locus_tag="BAY61_31880"
     CDS             9003..9776
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017577211.1"
                     /locus_tag="BAY61_RS32090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_31880"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_176879921.1"
                     /transl_table=11
                     /translation="MPERQFVSVDHPGIPMPDDMRSWSMPWRDYAPVDITPPPLRPDGL
                     PVSVAEGWAEQCVWPGDVPDWAERQAAALVPFSLDDHGWPLNPVGRTGRCGRNLGKWGE
                     NTAADPIVVAGSGADRHVLLIKRDDIGVWAIPGGMVDAGETAPSALVRELREETGVDLA
                     EITPTVLARTYVKDWRATDHAWVCSTVALYVLPEQRTAVAGSDATDARWWPFAGLEQLT
                     QDMGAAGEQLYEAHRPLLARALDQADIDAAAKGFS"
     gene            9845..9991
                     /locus_tag="BAY61_RS33250"
     CDS             9845..9991
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="BAY61_RS33250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_110057729.1"
                     /transl_table=11
                     /translation="MQESQQQEQSQAYEPPTVTEVGDFGAVTEGQYSRSISDDGDAGGY
                     WEQ"
     CDS_motif       9845..9931
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MQESQQQEQSQAYEPPTVTEVGDFGAVTE"
                     /locus_tag="BAY61_RS33250_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       9932..9991
                     /prepeptide="core"
                     /locus_tag="BAY61_RS33250_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="1.60"
                     /molecular_weight="2073.0"
                     /monoisotopic_mass="2071.8"
                     /core_sequence="GQYSRSISDDGDAGGYWEQ"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MQESQQQEQSQAYEPPTVTEVGDFGAVTE"
                     /leader_location="[9844:9931](+)"
     gene            10001..11803
                     /locus_tag="BAY61_RS32095"
                     /old_locus_tag="BAY61_31885"
     CDS             10001..11803
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="BAY61_RS32095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_31885"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_143021471.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.3e-33, bitscore:
                     110.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDADRLGLGRPHWWCALPDVAAAGPVASALATVGTVAARHPSGR
                     PWLLTAPAVRAPRIMRWGATVVAVLGEAIVDELNPAGTVAEWMRQVGSAHLVTAEPGRV
                     CAVADAAGFRRVFTAIAAGVAVAASHAEILRRLIDAPVDRGWVAAKLASPEMPSVLRES
                     RSPFVGVSPVAAGCVAELAGDAVRVRPWWRPPEPEKPLAEGAQLLRQALARGICGRARR
                     AGGRVSVQLSGGLDSAAIALLAAEADPLMVTTAGASPVDEDLSWARRIARTIPAGEHRI
                     FTVAEMPAFFARLEHPVAGMDEPCSFAAGGARQRFAGAALAERAVTLHFNGQGGDEVLL
                     APWAFLSGLLRRAPRLGWRHLRGFAALRGLRASAVMREALRGPGQFDSWLERAGSRLRR
                     EPVAAAAALGWEAPPLLPTWASSEAAELAIAALAAAPRTPVHPDAAVHAAVVRIRASAY
                     RAALYADAMAVAGAPTVMPFFDHEVLTACLSTRPEVRTDPWSPKPLLRNALQRDVPTEL
                     LARRTKGHYNTDIYRGWRTHRDDVRAMLAESRLVELGLVDQQVLVDELAAFGPSGLPPA
                     FVTDLIALEIWLRQESPPLTWGDR"
     gene            11869..12099
                     /locus_tag="BAY61_RS32100"
                     /old_locus_tag="BAY61_31890"
     CDS             11869..12099
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.4"
                     /locus_tag="BAY61_RS32100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_31890"
                     /product="PqqD family peptide modification chaperone"
                     /protein_id="WP_170140331.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 4.5e-14,
                     bitscore: 45.7, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.9e-13, bitscore: 43.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAQVSDGLVVVDERRGRTVHLNTTAATMLRALLAGGQDAAITV
                     VCQRFGVTEDTARDDLSALITDLARRKLVRR"
     aSDomain        11872..12096
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BAY61_RS32100_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="7.50E-15"
                     /identifier="RREFam002.1"
                     /label="BAY61_RS32100"
                     /locus_tag="BAY61_RS32100"
                     /protein_end="76"
                     /protein_start="1"
                     /score="45.7"
                     /tool="antismash"
                     /translation="STAQVSDGLVVVDERRGRTVHLNTTAATMLRALLAGGQDAAITVV
                     CQRFGVTEDTARDDLSALITDLARRKLVRR"
     gene            12096..12545
                     /locus_tag="BAY61_RS32105"
                     /old_locus_tag="BAY61_31895"
     CDS             12096..12545
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090021.1"
                     /locus_tag="BAY61_RS32105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_31895"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_091810593.1"
                     /sec_met_domain="PF13471 (E-value: 1.2e-19, bitscore: 63.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPIVLEQPARLALGEQLRARTAVAAAWLLLALVRARPARLRRL
                     LRVLHRGARPAPVEVALRARAMVATVSLHAASDHGCLLRSVAIVLACRFAGVAVTWRVG
                     VVSPPPALHAWVEADDKPVGEPFDPRWLYSPIITVEPSRKGILPR"
     gene            12542..13711
                     /locus_tag="BAY61_RS32110"
                     /old_locus_tag="BAY61_31900"
     CDS             12542..13711
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013315.4"
                     /locus_tag="BAY61_RS32110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_31900"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_091810592.1"
                     /sec_met_domain="PCMT (E-value: 3e-33, bitscore: 108.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTTGHLDLDQRLARYAADLRELGAIRSPAVQKAFATVPRHRFL
                     RSFYYRADRYTLAPGELPSARLLDVIYANNALFTHDGSDGDPTSSSSGPSVMAKMLEAL
                     DLRPGMRVLEIGGGTGYNAALLAAITGAEVTAVEAGRVAAANAGATIDELGLADRVRVV
                     HADGYHGDPAGGRFDRIIATCGIAGVPPVWLDQLVEGGMLLAPIAHAGVHPILTVQTAG
                     RVTVQGRCALWADFMPAAGNLRPSVLFAHDPNTSISADNVGRDVAAVPAAGPDRYNDLG
                     FYLGVRDARTNRAYLDAPEFSPAAGSTALVEDDAAVWVQHNGDLLHAGPESTIAPLREQ
                     LHQLVHEWDSSGQPAATEWRARFAPASGTPAPLLVPSQWECADASPSAR"
     gene            complement(13998..14285)
                     /locus_tag="BAY61_RS32115"
                     /old_locus_tag="BAY61_31905"
     CDS             complement(13998..14285)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31905"
                     /product="hypothetical protein"
                     /protein_id="WP_091810591.1"
                     /transl_table=11
                     /translation="MTSSINTEMATIEQRLTVLTKVREVFPDAAPGKLMGIVEWIVTGA
                     MPLNPAALEVAAKRLAAADDADWNAYHTDRNRYRGMVATTLDAYFAATHR"
     gene            complement(14373..14846)
                     /locus_tag="BAY61_RS32120"
                     /old_locus_tag="BAY61_31910"
     CDS             complement(14373..14846)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31910"
                     /product="hypothetical protein"
                     /protein_id="WP_091810590.1"
                     /transl_table=11
                     /translation="MKPIVDADIDVTGTVFHMDVEAEGTAGDIVTVAYATTEDGKTARV
                     MLRIPADGANYIRRNIEAATPTPAAAEKGLGVDTREHRTELIWSETGNAAWAERAGWSL
                     YVDAELIAHTAEALRADQATEWANRQLAEGMIWLQGHATSSFYWVASPSTRLR"
     misc_feature    14940..14953
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.26"
                     /tool="antismash"
     misc_feature    complement(14941..14954)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.95"
                     /tool="antismash"
     gene            15003..15293
                     /locus_tag="BAY61_RS32125"
                     /old_locus_tag="BAY61_31915"
     CDS             15003..15293
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31915"
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_091810589.1"
                     /transl_table=11
                     /translation="MSGDPQRPNVASVQEVPAPDARKRMPELIEDVRAGGIVYLTRYDH
                     RIAALVPVELAENIERIEDEYWSQRAAQARANAADTVPWDHAVAELEDGSQ"
     gene            15326..15565
                     /locus_tag="BAY61_RS32130"
                     /old_locus_tag="BAY61_31920"
     CDS             15326..15565
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31920"
                     /product="hypothetical protein"
                     /protein_id="WP_091810588.1"
                     /transl_table=11
                     /translation="MRSLAQLNKPLRRRVQTAVDTLGTNQHPVGATALTGQSGVFRLLV
                     ADVSVLYEIRSDGQVLVLVIEPAPRLASPLPEPD"
     gene            complement(15781..17049)
                     /locus_tag="BAY61_RS32135"
                     /old_locus_tag="BAY61_31925"
     CDS             complement(15781..17049)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013015.4"
                     /locus_tag="BAY61_RS32135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_31925"
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_091810587.1"
                     /transl_table=11
                     /translation="MVDRRRVVLLADVDAMYVSTERVFNSALTRRPVVVLSNNDGCVVA
                     RSREAKALGIGMGEPWFKVKARPDCRAVTALSSNYELYGDFSARLATVCAQLAAAVEQY
                     SIDECFLEAPETEAAEIARQVRECAARWLGLPVTVGIGATKTLAKIATNHAKDTGIGVF
                     NIDGLDQAELAELLASIPVGDVWGIGTRLSARLATQGVATAGALAQLDPGWVRRAYTIV
                     VERTVRELQGVPCIPLAAQPAPRRSIMHCRHLGQPASTQNEVAAAAGAFAQAVSAKLRR
                     FGLAVPAITVMLSTGGFGPGPHHHGQATQGFPVPRNAAGQLATAAARLARDTWQPGHRY
                     KRIGVLASDLVPATSIQPLWPDDPRHDRLATTLDTITARYGQGRVGYGSTGVREPTQWS
                     WRMRQDMRSPRFTTRWDEIPVVS"
     misc_feature    complement(17020..17022)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17157..17567)
                     /gene="umuD"
                     /locus_tag="BAY61_RS32140"
                     /old_locus_tag="BAY61_31930"
     CDS             complement(17157..17567)
                     /EC_number="2.7.7.7"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene="umuD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020502349.1"
                     /locus_tag="BAY61_RS32140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_31930"
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="WP_245866334.1"
                     /transl_table=11
                     /translation="MDVIEVEWPPMVAAGFPSPAEDYYTGPVSLDRNLIRNPASTFVLR
                     VSGDSMIEAGISDGDEVLVDRSLTPGDGDVVVAVLHDEFTLKRLRLRPPRLEPANPEFP
                     VIPVPRDGEGFDVWGVVTTVIHHLKPGGARGR"
     misc_feature    complement(17585..17600)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.02"
                     /tool="antismash"
     misc_feature    17586..17599
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 22.07"
                     /tool="antismash"
     misc_feature    complement(17586..17599)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.21"
                     /tool="antismash"
     misc_feature    17587..17607
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.2"
                     /tool="antismash"
     gene            17759..18169
                     /locus_tag="BAY61_RS32145"
                     /old_locus_tag="BAY61_31935"
     CDS             17759..18169
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31935"
                     /product="hypothetical protein"
                     /protein_id="WP_143021469.1"
                     /transl_table=11
                     /translation="METTGEPRYWDSSDTDVPVLVAARRQQQAAAEVAAELMGLAQRHR
                     LPMPSWMIPPPQIDPRYDLPVEAAALRGHLLPPQGREHWQRWVEVLSYHWPPMKSPVLG
                     EHCTGWWAVPYDRLGVPDHVVIELVAPNTDDE"
     misc_feature    17867..17869
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18207..19088)
                     /locus_tag="BAY61_RS32150"
                     /old_locus_tag="BAY61_31940"
     CDS             complement(18207..19088)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020640101.1"
                     /locus_tag="BAY61_RS32150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_31940"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_094168543.1"
                     /transl_table=11
                     /translation="MPLPVRYSVTSPYDISPSVVPVGVDPNRASIARVYDAALGGKTNY
                     AVDREVLDAAMRVHPGVAELAWANRNFLTRVMRHLAGHVKIRQYLDCGSGLPTAENTHQ
                     IAQRFDRSASVVYVDNDPVVLAHGRALLATNDATHILDANIFEPDQVLNHDLVTTHLDF
                     DEPIAVLLLSVMHHHLDTAECARIVRRYADALPADSYLALSHLIDPETPGLTPVAKGLE
                     QVALNSKMGSGTFRTRAEIETLTALDGYDMLPPGPGEAPAVVACDRWWPDGPVEPLTPT
                     QECFAGVVLRKR"
     misc_feature    complement(19112..19126)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     misc_feature    19301..19310
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    19478..19498
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.91"
                     /tool="antismash"
     gene            19543..20430
                     /locus_tag="BAY61_RS32155"
                     /old_locus_tag="BAY61_31945"
     CDS             19543..20430
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31945"
                     /product="hypothetical protein"
                     /protein_id="WP_143021500.1"
                     /transl_table=11
                     /translation="MLLKTAEAGKVSYLTRDGRAHAAVVPVAVGRAYEEQAGLSDSVRA
                     EIAAAVDRARTEITTVLARLDEEVCGHRLPAAADLPEDIPPRVGEPDVDVIISRENGDV
                     EIVPAAETPRPDEESAPGATWVGADDPLLVTLQEQVCGRWGFQAIPWTRIQSAAEHRGV
                     RLTSRAHLHRELRRILGDGAPEPIKQARSWCYVTIELWAAINAALTHHGQPLTYHRPYP
                     AVQAFVDLLPAMLAACEGRDTAPRQDEIAGAIRAAAGVPVPATTASRLGWVAQHYHHHR
                     CPWIDTLGGKPPRT"
     gene            complement(20485..20730)
                     /locus_tag="BAY61_RS32160"
                     /old_locus_tag="BAY61_31950"
     CDS             complement(20485..20730)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_31950"
                     /product="hypothetical protein"
                     /protein_id="WP_091810729.1"
                     /transl_table=11
                     /translation="MSADIPDITDPIDVARLAFSAEDGVIEGDLTWQSYVDTDADGSIT
                     VDVYADHVTMDDGQGRGFRYRVEYLGAAPTFSGHEA"
     misc_feature    20739..20752
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     gene            20896..21168
                     /locus_tag="BAY61_RS32165"
                     /old_locus_tag="BAY61_31955"
     CDS             20896..21168
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018832112.1"
                     /locus_tag="BAY61_RS32165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_31955"
                     /product="hypothetical protein"
                     /protein_id="WP_245866335.1"
                     /transl_table=11
                     /translation="MVLFGGKPPCEDGVMPSEHREPALTVRPPADLKRDAQATLAERGL
                     QMRAFVVACLAALINDPERFLATLRPHWPDKKPHLGGRAASKREQ"
     gene            21204..21476
                     /locus_tag="BAY61_RS32170"
                     /old_locus_tag="BAY61_31960"
     CDS             21204..21476
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009086587.1"
                     /locus_tag="BAY61_RS32170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_31960"
                     /product="hypothetical protein"
                     /protein_id="WP_143021499.1"
                     /transl_table=11
                     /translation="MVVGEACDPRRVGNEHPDLIDLDDGEMFEWVAEPAGGGEAGYANT
                     DDHDFAWPRHVLEEGRRIAVMREVAPAELKRLHQVREDDDPEYHR"
     misc_feature    21581..21595
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.52"
                     /tool="antismash"
     misc_feature    21630..21645
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.19"
                     /tool="antismash"
ORIGIN
        1 tctcgaaggc tttgttcaac atcgggaagg cgctgcgggc attcttggcg tggatggccc
       61 atttggagcc tttgctgggg ctgggggcga actgggagcc gatagagggg gagctgagtc
      121 ggttccggcc cctcaatgtc gctggccttg gaagtggtca tgccccgtag ctttcctcgc
      181 caactgggaa ctcaccagcg tacgcgcgca cttgacaggc gccagtcgta cgtgcgggtg
      241 cgcgcgcacg tacgaatctc caatcggagt aactgccacc gcttgcatgt aaagattaag
      301 gactttaaag tctttcctgt gagtgcagtc gagagttcag gtcaggtgac catgcagaac
      361 gtacgcgccc agctctccga gctcggtgag cgtgttttcc ggaacgggga acagttcatc
      421 gtctaccggc agggcaagcc gttctttgcg atggtgccgg taccggacgc cgagatgatc
      481 aggcaggtga aagccagcaa caagcccgag tgaggtagtt cgtcctgacc gaggcggaag
      541 accacttcca catgacgacc gccccggcca gaaccacaaa gcccctgaca ccgtttgaac
      601 gatcccagga gactttcagt gtctatcacg tctttgcgag ctgggcaggt gcgcgccgag
      661 aacctgttca agattgctca acagcagcgg gcggcggctg cgacgctcga ggagcgcacg
      721 accttgtcgg cttccgaacg cctggaggcg gccgagctgc gtagccacgt cgccatgatc
      781 taccaggcga taggagaggc gtacccgatc tgggcacggc tgtgggagcg cttggccgcc
      841 gcggagtatg ccgccgcagg ccgccatgag ctcggcgcgt acctcaccga agaccaggta
      901 caagcagcat gaactcccgt cgaccggcga tccgctaccg gaggacactg ctgttcggcg
      961 cctcgctggt cttatggcat tcacgagcag catgtcggcc ctgagcttcg ttgccgacga
     1021 accggttctc ggatttgcct gcctgagcgg cctcttctcc atgttcgcgg taaccgatcg
     1081 aaggctgcga cgcgagcacg ccagcaccgc agcgctgcgc tgcgccccga tgcagcggcc
     1141 cctaccagga gtaggcatga aggtcggcgc tactggcagc agccgcctcc cagccgttca
     1201 aatccctacc gctggtgagt ccgcaagcct ttgaacaggc aatacgttac ttactgtgat
     1261 cgaaaacaag agagaaggga ctggtcgatc gtgatgaccg taagggcgtc gaaggttcgt
     1321 cctggcgaca gtctgaaggg ttacgagagc acgccggggg cggtggcaag cgttcattgc
     1381 agccgcttcc tccgggtgtt cacccacaca acgtccggtg agcggatcac cttccgctgc
     1441 tggagccgcg ccaggctcgc aaaccgctga tcaaccgcgt cgtcaaccca gaaaccaaga
     1501 caaaggagag gaccccatgc gcaagaccag gttgcacgag ctcgtcaccg aactggtgca
     1561 gaacacatgg aacagcgacg acgcggatgt tgctcaggcg gtcctcgacg acgagaacgc
     1621 ctttggtgcc tgtgccatcg gctgaacgac gccggtgatg gtgagcatga cggaatcgag
     1681 gacgcctggt acgagctagt cgacgacctg tccgacaacg acctggactt catcgccgac
     1741 gaggccgatt caccggcggc ctacctggcc tcccagatct aggaagaacg catcatgaac
     1801 aacttgaaga tcgcgggcta gctggctgaa cagtagaagc acacagctgt aggtgtccgg
     1861 atgcagccgg tcgccaacgg aaattgatcc gaagggaaca gcaagatgac cacgacgatt
     1921 catccggagc agtgggctgg tgagatcacc gcccagcagg ctctggactt ctatgagcgg
     1981 cattccgcac tggggcttgt tgcgatgcag gcgctgcttt cgacgtcgga cctgtcgctg
     2041 cacgcggcgg cgctgacctg gctggccgag ggcgcgatgg gggaggcggc ggtcgcctgg
     2101 caggtgttca acgacccggt cgacggcaac ctgagcaact tcaccccgac cgagcgcgcc
     2161 gaaatcatcg aggagcacat cgaaggcgcg cggatcgtcc tgcgcctggc cgaggccgct
     2221 cgggcgaagg tcgagggcaa gcagcgtccc tgcggggcgt ggccagagct ggaggacgtc
     2281 gccggtgacg tgcttgatct gctggccgat ccggagacgc ggtcggcgaa ggagatgtcg
     2341 gcgctatatg gggacctgat ccagccgctg ttggatctgg ggtcgtatcc cgagacggtc
     2401 gcgcagttgg tgagtgtgtg gtccgagcac gccgagaacg acgagacctt ggacgcgttg
     2461 gagagcgcga tccggtcctg acaggcgaat gccctggtgg gcggggatgc agccccgttt
     2521 gtgcccacca gggcatcgaa cgcgacccca accgatccga agggaaagac gcgcactatg
     2581 aacgatgcac caagagtagc gacatcgcca agcctgccgg gttcggaggt cgtcgaccgc
     2641 gttgtcgacg gaccgaagtc gtcgcctcgg tccccgtgcc atctgcggcc agtcctggtg
     2701 gacgtcgagc gcgtccgtac cttgctcgcc tgaattcgcc cagccctgcg gcggcttggg
     2761 cgaggggcgc tgatggcgct tctgtgctcg gcgaacgctg cgggcctgca tggaatggga
     2821 gcaggccatg tcgtctgcat tgcaacggtt tcatcattct caccagcgca agcgcaacaa
     2881 caccgagtat tggatcggcc agctgtacgc gacggccgat ccggcggaac gggtcgccgc
     2941 gctgggccag ctgctggagc gtttcgagct ggaggtcgcc agcgcgtggc ttgtgggcga
     3001 cccgaatcgg gcacggaatc tggagggcca ggccgaggcg ttcgcggtct ggcgagaagt
     3061 cgagctgggg gttcttgctc cggaagcccg gcgcccggcg ccggtagcga ggtgaccggc
     3121 gttgggcacc gtcaccgcgc ttcgcgtcgc cggggacatg atccagctct gggacgagac
     3181 gtactggacc gtcgacgagt gggtcgatgg cttgccggcg tgggaatggg ggcatgcccc
     3241 gcgggggctg gccacccgct cgcaactgcg tgatctgccg cagccgaagt cgatcggccc
     3301 gcaggacccg tacgggctgc tggtcttccg gcaccgcaag gccgctcgcc gccgggagat
     3361 cgctcagctc taccgcattg acctggcgcg cgaccggcgc gccgtgactc cggccgtcct
     3421 ggcctcggtg gagaaagcca tgctcgcgcg ccgcacttgc cggcgttgcg gacaggtgca
     3481 gccgcggtgc gtctcgacgc tgacgcgcac gtgctggccc tgcatggaga tcaccgggga
     3541 tttcggccaa cgcgaacaac acgccgcttg aacagcgcga atcctgcgat cgccgcgccg
     3601 cggcgggcgg gattcggcat cgaactcgag gagaacacga tgtcacgcac attccccacc
     3661 actgcggctg tcgccgctgc ggctgcggcc gctggctggt tcgttaccgg ccagcggctg
     3721 cggcggcgca ccagcgaatt gttcaccgcc gctaccgagt tggaggccgc cagcagcaag
     3781 ctggagcact cgctcgtcga cccggtttcc gggctgctga ctcgtgtggg ctgggacgcc
     3841 tgcgcggcgc agcgggccgc cactgcgaac gcctttctgc tgctcgacct gaacgccttc
     3901 aaggcgatca acgacagcct cggccacctt gtcggcgacg cggtcctgcg ggccgtcggg
     3961 cagcggctga tgaccgagtt tggggaggat gccctgctcg cccggccggg cggtgacgag
     4021 ttcaccgtcc tgaccacgtt gaccctcgcg gcgctgcacg agcagatgga acgtctggtc
     4081 gagatggtca ccgcaccggt cgaggtgccg gatgtcggtg agctgaacat cggcgtctca
     4141 gttgggctgg tgtggctgtg cgatctgccg acctggagcc tggacgcacc ggacgaggcc
     4201 gaggcagacc tgtggacgtc ggtggtgcag gaagcgttcg cggccgcgga tatcgcgatg
     4261 tacgacgcga aggcgatgca ccgcgggtgg cggatctacg accgggatat cgacccggtg
     4321 cggccggcca cggcaatcgt gccaggccag cagcggcgct accgggacta cggcccggcc
     4381 gcgctgcgcc accaggaggt agtcgcgcga tgaccgcggc acccagtccg gcggaggctc
     4441 tgcttgagcg catccgcagc cgctacatcc gaccggtcaa ggtgcagcgg aacggtcacc
     4501 tgcgcgacga caacctgttg ccggcgatcg gcccgacccg cgccgggctg ggcgggttcg
     4561 agatccagat gctcgtgacc tgctctggcg cccggtgatg ggcacggccg cgcagcgtcc
     4621 ttgcgcccgg tgcaagcgat cgatggcgat gacccggaac gtggcccgcg gcgggcgcgc
     4681 gcacaaatcc cgtggcctct gcgccgggtg ctacgtggtc gtgctgcgcc acggcgaact
     4741 cgagctatat ccgcggctgc gccgcaaccg cgacgaagtc ctccatgagt tccagcacct
     4801 gcgtgaacag ggcattcgca gccatcgcga cctggccagc gcactgcgga tgaccgaggg
     4861 cgcgctgtac aacatgctcc gccgtgcccg gctcgccggc gatcctcgcg cccctgacta
     4921 acgcatgcgg acacctcgtt ctcgcccacc aacccacttc gacgaagggc tggaccattc
     4981 ccgtggcacg acccgatgcc tcagctcggc gagttcgagg tcgccgagca atccgcgtgg
     5041 cctggccggc tacgccgccc ggtggcgaac gcgcaacacg gagttcctgc ggatctgaac
     5101 ccgccacgac ggcccaggtc agcaagaatt gtttgtctgg aaaacggcgt ccaagccaag
     5161 ccgctgggat tgccgcggcg tgacggtgtc ccgccgtgcc gtcgacgagc gcctggtgga
     5221 tgtccaaagt cgacaagaag gcggcgggcc gccagctgga tggccaggtc tggaacgagc
     5281 agcccacgcg gcatttgccg gtgccgtgtg agcttgttac accacgtgag tcggtggggg
     5341 atgatctgcg gctacggtag ccgtgacgct gctgagcagt accggggcta ccaacgacgg
     5401 aggcccgcgc cgacgagtcc ggcgcgggcc tccgctcgtg tttccgagct acacggcggt
     5461 taggcgatca ggtgatcgaa ttcgccgttc ttcgcgcctt ccaggaaagc ggtgaactcc
     5521 gacttggtga agccgagcgt ggtccgcttg tccttcggct tgtcggggta ctccttgctg
     5581 tcctggacac cgatccagcc gtccgtcgcg tagagcatca cgcagtcggg ctggctctgc
     5641 ggcgagcggc tggatttgat gtagtcgccg tcgcgcagcg cgtcgagcgg cggctgttct
     5701 gctgccatct tcttctcctc actcttcacg ggcgagctga ccaggcgtcc cggctggagg
     5761 gccagtcagc tctgtccgca tcaccccgca tcacgcaacg cgcgggggat gcggcgccgg
     5821 atcaccgtaa cggcgccctg gtcacaagat cagatccgcc cagaccttct cgatgcgctc
     5881 gcgggattgt tcgacgtcga gtgccttgct ggcggccacg ctccacatgt tgttgtagta
     5941 gcgcagctcg gagggcttct ccaggaaccc gctcgttggg gcgaactcga tgaacacaca
     6001 ctcggggtct tcgggatcgg cgaactccat gatttcgaaa ctcatgccct gcgcggcgta
     6061 gacgtcggcc tcgaacggca cgatcagcac ctcaacggtg gcggtccact gggtgtcgag
     6121 caggtaccgc agttgccggg ccaggacttc gcggccgccg acatggcggt gcagggcgcc
     6181 ttctgcgatc acgacggtgt agcggaagtt ggggtcgttg agccggtgct ggcgcttcat
     6241 gcggaactcg acgctgcgcg ccatgtcgga gggtttggtg ttctgcgagg agtacacgac
     6301 ggcgtggctg tactcctcgg tcgtcagcat caaggggatg aacgcctcga tgtactgcct
     6361 gatgtgtgcg gcgtcggatt ccagcccggc cagcatctcg ccgtgttcct ggatgacgtc
     6421 ggcgtattcc gaccaccagc cgagctgatc gccctcctgc cacagctcgt accacaattc
     6481 agcctgctca gacgaaagct ccagaacctc ggtcatcttg cggatctgga ctttggtgag
     6541 ggtggctttg ccgctctcga ccctggacag cctggcctgg ttgatcccgc cgatgcgctt
     6601 ggccaactcg gtgccggaca tcttgcgttc ggttcggcga tcgcggatct gcctgccgag
     6661 acgccgtcga cgcagcgttg ggctgaccgc tccgtctccg ctcatctgca tccacctttc
     6721 tggacctgga ccactctccg tgcccctgta gcccgttctc agaccgctcc tcgcggccgt
     6781 tcacccgatc ggcactcttg actattcaaa acatattctt ggaatatgtt ctacatagcc
     6841 gtcggggtgc tgtgcaagcg aaggtacccc gaccggctca caggttggag gaaggcccgc
     6901 tccggtggcc cccaacagcg ttgagctggc cttcctccga cgcacagaga ctgcggcggc
     6961 tctctgcctg cccccgactt gcaggggtcg ccgcgaccaa ccggcaacgg gagccgtgat
     7021 ggaagagcta gtcaggacag cagcaccgtt tgtggtgcgc ggctgtgtcg ggggtgcccc
     7081 ggtggaacgt gccgtgtgtt cgaccgacga agctgagcgg ctcgctcaac tcgccgcgac
     7141 cgtcgacgac gaatcgtggg cctcctggat ggtgctgccc gtcgataagc agggcgctac
     7201 cgagctgatc gtgctgttcg cccggtatcg acgtggcctg gtcggcgaga cgcagcggca
     7261 gatacacgcc atcggcatcg ttgcgggccg cctgctggcc cagtccctga ccgctgcctg
     7321 cggagcccgg ctgcttcgtg ctcagctcga gttcacagct ttcggcgagg gaatgccgtg
     7381 tgagcggtgc gtggcgaagc tcagcgtcaa cctccccgca gcggacgagg ccacaccgga
     7441 gctgcccgat ctgccccccg acgtcgacgt cctccgcacg caattcggcc atacctccgt
     7501 ctccccgccc caccgcggcc cggccgagat tccccttgca ggtcaagcga agcggcggcc
     7561 cggcgccgtc gaccacgccg cctcgagagc gcggtggacg ccatgaccga ctccccgttc
     7621 cccgacagcc ccctggagcg ccgcgctccc ggcacgcacc tgcccgccca ggcgtacacc
     7681 ggcccgatcc agtggccgac cgaggacccg gacaacccgt cgccgcattt cgcgctgatg
     7741 acgcgaacgc ttgaagggtt gcatcgctac gacccgccgg cgcgcccgcg tcatgctgcc
     7801 gcagaggact tccggggctg gatgcagccg cccccggagg gcaaggagca attcccaatc
     7861 gatccaagga tgtgaaggcg atgatcgcca ccctgtcgga gaacgagctg ccgacgctgg
     7921 cattggctgc caccgaccgg ccggaacgcc cggccgttcc ggtgcccgtg ggcgactgcg
     7981 ggttcatggc catgctgcgc gaagccgagc cggacctcgc gcacgcccag cagagccatc
     8041 gcgccgacgg cgaagtgctg cacgtgtggc ggcacgccta cacgcacgag tacgtcgtgc
     8101 tgatcgtgcg tgacaacggc cgccacggtg tgaaggagtc cggcgccccg ctctacgacc
     8161 ggctctcgca gctggccgga atgtggctgg ccagtgaaag cccgcggcga ggtggtgcgc
     8221 ggtgagcacc gtcgttgcct tcgcgacctc gcctaccccg gagtggtccg aggccgagat
     8281 cctggcctgt gtcgcggcca gcaccgtgaa accggaaccg gcgtgggtgc cgaaccacct
     8341 ggagcgcccg caactgcgcg cctacctcgc cgcgcggttt cccgaacttc ggtacgccta
     8401 cgccgaaacg gagccgggcc tggagatggt gcacgtctgg ctcgacccgg cgtccggctc
     8461 gtgggtgcag atgaccgaga acctgcgatg gggcccgacg atccgcagcg acggcccccg
     8521 cacgctcctc tatgaggacc tgatctgcgc gatcggtgac tggaaccgcg acggccggcc
     8581 cgacgtccgg gacgtgcgcc cgggacaggc cggttgctga tggcgtggca gttcggcggg
     8641 ttggtgctcg gcgcggttct ggtcggggtg gtcgcgctgg tcatcctggc cggaatcgtg
     8701 ctgtggctgc acacccgccg agctcgtcgc caccagagct acgtcgagca cgaggaaacg
     8761 ccggcgcagc aacgagttcg ccatatgcac cggcaggacc gctatctcga tgcgacacag
     8821 cccattcccc gccacccgcg gtgaacgagc tatcgaagac caactggcga acccccggcc
     8881 ccggcccgga caccgagctg tccgggccgg ggtcccgcta cacatcaggc acgagcacgt
     8941 tgacacctca gcctgtcagt gaagaagcgc ggtactcccg cctctattgg aaagggcttc
     9001 cgatgccgga aaggcagttc gtctctgttg atcatccggg cattccaatg ccggatgaca
     9061 tgcgttcctg gtcgatgccg tggcgcgact acgccccggt cgacatcacc ccaccaccgc
     9121 tgcgtccgga cgggctgccc gtcagcgtcg ccgagggctg ggcggaacag tgtgtctggc
     9181 cgggagacgt gcctgactgg gccgagcggc aagctgctgc gctggtgccg ttttcgctgg
     9241 acgatcacgg ctggccgctc aacccggtag gccggactgg gcggtgcgga cgcaatctcg
     9301 gcaagtgggg tgagaacacg gccgcggacc ccatcgtcgt cgccgggtcc ggcgctgacc
     9361 gccatgtgct gctgatcaag cgcgatgaca ttggggtatg ggcaatcccc ggcgggatgg
     9421 tcgatgccgg tgagaccgct ccctctgcgc tcgtgcgcga gctgcgcgag gaaaccggcg
     9481 tcgacctcgc cgagatcacg ccgaccgttc tcgcgcgcac ctatgtgaag gactggcgtg
     9541 ccaccgatca tgcctgggtc tgctccaccg tggcgctcta cgttctccct gagcagcgaa
     9601 ccgcagtcgc cggctccgac gccactgacg cccggtggtg gccgttcgct ggcctggagc
     9661 agctgacaca ggacatgggc gcggcgggcg agcaactata cgaagcacac cgcccgctgc
     9721 ttgctcgcgc gctggaccag gccgacatcg acgcggcggc caagggattt tcgtgaccac
     9781 atccaccaac cagagttgtc ctcgaccaga tgggccgagg aagtcgagaa ggaggaagtt
     9841 gttgatgcag gaatcccaac agcaggaaca gtcccaggcg tacgagccgc cgaccgtgac
     9901 cgaggtgggc gatttcggtg cggtgactga gggccagtat tcgcggtcga tctccgatga
     9961 cggggacgcc ggcggctact gggaacagtg atcggctctg atgtccgacg ctgatcgcct
    10021 cgggctcggc agacctcact ggtggtgcgc gctgccggat gtagctgctg ccgggcccgt
    10081 ggcgtccgcg ctggccacgg tgggcactgt ggcggcgcgg catccgtccg ggcggccgtg
    10141 gttgctcacc gcgccggcgg tgcgtgctcc gcggatcatg aggtggggcg cgacggtggt
    10201 ggccgtgctg ggggaggcga tcgtcgacga gttgaacccg gcgggcaccg tggcggagtg
    10261 gatgcggcag gtgggcagtg ctcacctggt gaccgcggag ccgggccggg tgtgcgcggt
    10321 ggcggacgcg gcgggtttcc ggcgcgtgtt caccgcgatc gccgcaggtg tggcggtcgc
    10381 ggccagccat gccgagatcc tgcggcgcct gatcgacgcg ccggttgatc gcgggtgggt
    10441 ggcggccaag ctggccagcc ccgagatgcc gagcgtgctg cgcgagtccc gttccccgtt
    10501 cgttggggtg tcgcccgtgg ccgccgggtg tgtcgccgaa ctcgccggcg acgcggtccg
    10561 ggtgcggccg tggtggcggc cgccggagcc ggagaagccg ctcgctgagg gggcgcagtt
    10621 gctgcggcag gcattggccc gcggcatttg tggccgcgcg cgccgcgcgg gcgggcgggt
    10681 gtccgtgcag ttgtccggcg gtctggattc agcggcgatc gcgctgctgg ctgccgaggc
    10741 ggaccccttg atggtgacca cggccggggc gtctccggtc gatgaggacc tgtcctgggc
    10801 ccggcggatc gcgcgcacga ttccggccgg cgagcaccgg atcttcacgg tcgcggagat
    10861 gcccgcgttc ttcgcccggc ttgagcatcc ggtcgcgggg atggacgagc cgtgctcgtt
    10921 cgccgccggc ggtgcacggc aacgcttcgc cggtgccgcg ctcgccgagc gggcggtcac
    10981 gctgcatttc aacggtcagg gcggcgacga ggtgctgctc gcgccgtggg ccttcctgtc
    11041 ggggctgctg cggcgagcac cgcgcctcgg atggcggcac ctgcgcggat tcgccgcgct
    11101 gcgcgggctg cgagcctcgg cggtaatgcg cgaagccctc cgtggtcctg ggcagttcga
    11161 cagctggctg gaacgtgccg gctccaggct gcgccgggag ccggtcgcgg cggccgcggc
    11221 cctgggctgg gaagcgccgc cgctgctgcc gacgtgggcc agcagcgagg cagccgagct
    11281 cgcgatcgcg gcgctcgctg cggctccgcg aaccccggtg catcccgatg ccgcggtgca
    11341 cgccgcggtc gtgcggatac gcgcctcggc gtatcgcgcc gcgctgtacg ccgacgcgat
    11401 ggccgtggcc ggtgcgccga ctgtgatgcc gttcttcgac cacgaggtgc tgaccgcgtg
    11461 cctgtccacc cggcccgaag tgcgcaccga cccgtggagc ccgaaaccgt tgctgcgcaa
    11521 cgcgttgcaa cgggacgtcc cgacggagct gctggcgcgg cgcacgaaag gccactacaa
    11581 caccgatatc tatcgcgggt ggcgcaccca ccgcgacgat gtccgcgcga tgctggctga
    11641 gtcgcggctg gtcgagctcg gcctggtcga ccagcaggtg ctcgtcgacg aactcgccgc
    11701 gttcggaccg agcgggctcc cgcccgcgtt cgtcaccgac ctcattgccc tggaaatctg
    11761 gctgcgccag gagtcgccgc cgctgacatg gggagaccgc tgatggcgac actgctacct
    11821 cgccgccgac tcgacgaccc gaaccggccg tggcggtggg gccggtcggt gagcaccgcg
    11881 caggtcagcg acggcctggt ggtcgtcgac gagcgccgcg gccgcaccgt ccatctcaac
    11941 accaccgccg cgacgatgct gcgcgcactg ctggccggcg gccaggatgc cgcgatcacc
    12001 gtggtgtgcc aacgattcgg cgtcaccgag gacaccgccc gcgacgacct gtccgcgctg
    12061 atcactgacc tggcgcggcg gaagctggtg cggcggtgag cgccccgatc gtgcttgagc
    12121 agcccgcgcg gctcgcgctg ggcgagcagc tgcgcgcccg gacggcggtg gccgcggcct
    12181 ggctactcct ggccctcgtc cgcgcgcgcc cggctcggct tcgccggctg ctgcgggtgc
    12241 tgcaccgtgg tgcccgtccc gcgccagtcg aggtggcgct gcgggcccgc gccatggtgg
    12301 cgaccgtgtc gctgcacgcc gcgagcgatc acgggtgcct gctgcgctcg gtcgccatcg
    12361 tgctcgcctg ccggttcgcc ggggtcgccg tgacgtggcg agtcggcgtc gtctccccgc
    12421 cgccggcgct gcacgcctgg gtcgaagccg acgacaaacc ggtaggggag ccgttcgatc
    12481 cgcgctggct ctacagcccg atcatcaccg ttgaaccctc ccgaaagggg atactgccgc
    12541 gatgagcacg acgaccggac acctcgacct ggaccagcgc ctcgcccggt acgcagccga
    12601 tctgcgtgag ctcggcgcaa tccgcagccc cgcggtgcag aaggcgttcg ccacggtccc
    12661 acgccaccgg ttcctgcgct cgttctacta ccgggccgac cggtacaccc tcgcgccggg
    12721 ggagctgccc tcggcacggc tgctcgacgt gatctacgcg aacaacgcac tgttcaccca
    12781 cgacggcagc gacggtgacc cgacgagctc gtcgtctggg ccgagcgtga tggcgaagat
    12841 gctggaagcc ctggatttgc ggccagggat gcgggtgctg gagatcggcg gcgggaccgg
    12901 ctacaacgcg gcactgctcg cggcgatcac cggcgcggag gtgactgcgg tcgaagccgg
    12961 ccgggtcgcg gccgcgaacg ccggcgccac gatcgacgag ctcggcctgg ccgaccgtgt
    13021 gcgggtcgta cacgccgacg gatatcacgg agatcccgcc ggcggtcgtt tcgaccggat
    13081 catcgccacg tgcggcatcg ccggcgttcc cccggtgtgg ctggaccagc tcgtcgaggg
    13141 agggatgctg ctcgcgccga tcgcacacgc aggcgtgcac cccatcctca ccgtccaaac
    13201 cgccgggcgg gtgacggtgc agggacggtg cgcgctctgg gcggacttca tgcccgcagc
    13261 ggggaatctc cggccaagcg tactgttcgc gcacgatccg aacacctcga tctcggcgga
    13321 caacgtgggc cgggacgtcg ccgcggtccc tgccgctggg ccagaccggt acaacgacct
    13381 ggggttctat ctcggcgtgc gcgacgctcg aacgaaccgg gcatacctgg atgccccgga
    13441 gttctccccg gcggccgggt cgaccgcgct ggtggaggac gacgcggcag tgtgggtaca
    13501 gcacaacggg gatctgctac acgctggccc tgagtcgaca atcgcgccgc ttcgcgagca
    13561 gctccaccaa ctggtgcacg agtgggactc gtccggccag cccgccgcaa ccgagtggcg
    13621 cgctcgattc gcgcccgcga gcggaacacc ggcaccgttg ctggttccct cccagtggga
    13681 atgcgccgat gcgtcgccca gcgcccgctg acggaagcgc tcctccggca gcagctcggg
    13741 ttgcgagcac cttgtgtgtc gtcatgggcc gcaccatgcc gtgcggtacc aacgagccga
    13801 cccacactcc gccctgacca gcacggcctc agcaatggct tgtctattcg gctccgctat
    13861 gcagaggcca cgagctcacg ctccagtgcc tcagtcgagg tctcgcgaac tccccttcgc
    13921 tcggccgaga aggtgattgc agctggcagg gagaggagcg gcccagacgg cgcgggagaa
    13981 gaagtgggcg tccggggtca gcggtgggtt gcggcgaagt aggcgtcgag ggtcgtggcg
    14041 accatgcccc ggtaacggtt gcggtcggtg tggtacgcgt tccagtcggc gtcatcggcg
    14101 gcggcgagcc gcttcgcggc gacctccaag gcggctgggt tcagcggcat cgcgccggtg
    14161 actatccact cgacgatgcc catgagcttg ccgggagcag cgtcggggaa gacttcgcgg
    14221 accttggtca gcacggtcag gcgctgctcg atggtggcca tctcggtgtt gatgctgctg
    14281 gtcatcgggt tgccctttct ggttctggcg cgggtggtcg gtggagcggg gtgccgcaca
    14341 ccggggcgcg gccggtagtg ggaaaacacc agttatcgga ggcgagtcga ggggcttgcg
    14401 acccaataga aggagctggt ggcgtgcccc tggagccaga tcatgccttc ggcgagctgc
    14461 cggttggccc actccgtggc ctggtcagcg cgcagggcct cagccgtgtg agcgatgagc
    14521 tcggcgtcga cgtagagcga ccagcccgcg cgctcggccc aagcggcgtt cccggtctcc
    14581 gaccagatca gctcggtgcg gtgctcgcgg gtgtcgacgc ccaggccctt ctcggccgcg
    14641 gcaggggtgg gagtggcggc ctcgatgttg cggcggatgt agttggcgcc gtcggctggg
    14701 atacgcagca tcacgcgggc cgttttaccg tcttcggtcg tggcgtaggc gacggtgacg
    14761 atgtcgccgg ccgtgccctc ggcctcgacg tccatgtgaa acaccgtgcc ggtgacgtcg
    14821 atgtcggcgt cgacgatcgg cttcatgggc aaatccccat tcactcgttt ccactgttca
    14881 gcgtgctgtt tggtcggtca gcgcgctgat tcatgtcgtc aactttagcc gtctctgaca
    14941 ttttgtcaag aaatctactt tcgttatttc acgacgcggc ggccatctag tacgttttgg
    15001 gtatgagtgg tgacccccag cggccgaacg tggcgtcggt gcaggaagta ccggcgccgg
    15061 acgcgcgcaa gcgaatgccg gagttgatcg aggacgtccg ggcgggtggc atcgtctacc
    15121 tgacccgcta tgaccaccgg atcgccgctc tagtaccggt ggagctggcg gagaacatcg
    15181 agcgcatcga ggacgagtac tggtcgcagc gagccgcgca ggcccgcgcc aacgcggcgg
    15241 acaccgtgcc gtgggatcac gcggtcgccg aactcgagga cgggagccag tgagccggtc
    15301 cccggtggca attacccggt cggcagtgcg gtcgctggca cagctgaaca agccgctgcg
    15361 acggcgcgtg cagaccgcag tcgacacgct cggcactaac cagcaccctg tcggcgcgac
    15421 cgcgctgaca gggcaatcgg gggtattccg cttgctggtc gccgacgtct ccgtcctcta
    15481 cgagatccgc tcggacggcc aggtgctcgt gctcgtgatc gaaccagcac cccggctcgc
    15541 cagccccctt cccgagccgg attgaccgtg atcgccaccg acaagtaggt gtgacatgag
    15601 gccgacgagt tcgacctggt ccgccggatg gcctggtgcg ccatcggcga actgccaacg
    15661 gcgacccggg atcacgatgg ggttagcgct cggccttgcc gcgctcaata cgtagcgccc
    15721 gcgccgatgt tgccagtggt caggtcactg gtcacaccgg caacaagtgc atcggctggt
    15781 tcatgacacc acgggaattt cgtcccagcg tgtggtgaac cgtggcgacc gcatgtcttg
    15841 gcgcatccgc cagctccact gggtcggctc gcggacgccg gtactgccgt agccgacgcg
    15901 gccctgcccg taccgggcgg tgatcgtgtc gagcgttgtg gcgagccggt cgtggcgcgg
    15961 gtcgtccggc cacagcggct gaatgctggt cgccggaacg aggtctgagg cgagcactcc
    16021 gatccgcttg tagcggtggc ccggctgcca ggtgtcgcgg gcgagccgcg ccgctgcggt
    16081 cgccagctgg cctgcggcat tccgtggtac cggaaacccc tgggtggcct ggccgtgatg
    16141 gtgaggaccc gggccgaatc ccccggtgga cagcatcacg gtgatcgccg ggacggctag
    16201 tccgaaacgt cggagcttgg cggacacggc ctgcgcgaac gcccctgccg ccgctgcgac
    16261 ctcgttctga gtcgatgccg gttgtccgag atgccggcag tgcatgatcg agcggcgcgg
    16321 agcgggctgg gcggccagcg ggatgcatgg cacgccttgc agttcgcgga cggtgcgttc
    16381 gacgacgatg gtgtacgcgc ggcgcaccca gcccggatcc agctgggcaa gcgcgcccgc
    16441 tgtcgcgacg ccttgcgtgg ccaggcgcgc cgaaagcctc gttccgatgc cccatacgtc
    16501 acccacgggg atgctggcca gcagctcggc gagctcggcc tggtcgagac cgtcgatgtt
    16561 gaacactccg atcccggtgt ctttggcgtg gttggtggcg atcttcgcca gtgttttcgt
    16621 cgcgccgatt ccgacggtga cgggcagccc gagccaccgt gcggcacatt cgcgcacctg
    16681 gcgcgcgatt tctgctgcct cggtctctgg cgcttcgagg aagcattcgt cgatcgagta
    16741 ctgctcgact gccgccgcca gctgcgcgca caccgttgcc agccgtgcgc tgaaatcccc
    16801 atatagctcg tagttcgacg acaacgccgt cactgcgcgg caatccggcc gggccttcac
    16861 tttgaaccac ggttcgccca tgccgatccc gagcgccttc gcttcgcggc tgcgcgcgac
    16921 aacgcagccg tcgttgttgg acagcaccac gaccggccgc cgcgtgagtg cggaattgaa
    16981 aacgcgttcg gtcgaaacgt acatcgcgtc cacatcggct aacaggacca cgcggcgacg
    17041 atcaaccatg ccccgtctcc gtttgcgcta caagggttgc cgccgttact gcggctcgtt
    17101 ggctcccgga gaagctggcg tacgcgctgt cgggaaccac gagtccgacg cgctggtcag
    17161 cggccacggg caccgccggg tttcaaatgg tggatcacgg tcgtgaccac gccccacacg
    17221 tcgaaccctt ccccgtcgcg cggtaccggg atcactggga actccgggtt cgcgggttcc
    17281 agccgcggcg gtcgcagccg cagccgtttc aaggtgaact cgtcgtgcag caccgccacc
    17341 acaacatccc cgtcgccggg tgtgaggctt cggtcgacca ggacctcgtc tccatcactg
    17401 attcccgcct cgatcatgga atctccagac acccgcagca cgaacgttga cgccggattt
    17461 cggatcaagt tccggtccag actgaccggg cccgtgtagt agtcctccgc gggcgaggga
    17521 aagcccgccg ccaccatcgg cggccactcg acctcgatca catccacgca cgtcaccaac
    17581 tgagtcaaac atatgttcga ctagatcgcg ggtttcggac cgactttgtg agattcggcc
    17641 tggtcagacc gacgtgcgcg gtcaaactcc gggtctgccg ggaggcaatc cgacacaagc
    17701 aatctgcccc tcgggagacc tcccggcctg gtgcgtggat gcccgtatgc tcgcccggat
    17761 ggaaacgact ggggagccac ggtactggga cagctccgac accgacgtgc cggtgctggt
    17821 ggcggcgcgt cgccagcaac aggcagcggc agaggttgcc gcggagttaa tgggattggc
    17881 gcaacggcat cggttgccga tgccgtcgtg gatgatccct ccaccgcaga tcgatccgcg
    17941 atatgacctg cctgtcgagg cagcagcgct acgcgggcat ttgctgccgc cgcagggacg
    18001 tgagcactgg cagcgctggg tcgaggtgct ctcctaccac tggccaccga tgaagagccc
    18061 cgtactcgga gagcactgca cgggctggtg ggccgttccc tacgacaggc tcggcgtccc
    18121 ggaccacgtg gtgatcgagc tggtagcccc gaacactgac gacgaataag cctgcgcgag
    18181 tgatcgagca gcgacgccgg atccggtcag cgtttgcgca ggacgactcc agcgaaacat
    18241 tcctgtgtcg gcgtgagcgg ctcgacgggc ccgtcgggcc accagcggtc gcaggcgacc
    18301 acggcgggtg cctcgccggg cccgggaggc agcatgtcgt acccgtcgag tgcggtcagg
    18361 gtttcgatct cggcgcgtgt gcggaaggtg cccgagccca tcttgctgtt gagcgctacc
    18421 tgttccaggc ccttggccac gggggtgagt cccggggttt ccgggtcgat caggtgtgac
    18481 agcgccaggt aggagtcggc gggcagcgcg tcggcgtagc ggcgcacgat gcgcgcgcac
    18541 tcggcggtgt cgaggtgatg gtgcatcacg ctcagcagca gcaccgcgat cggctcgtcg
    18601 aaatccaggt gcgtggtcac gaggtcgtgg tttagcacct ggtcgggctc gaaaatgttc
    18661 gcgtcgagga tgtgggtcgc gtcgttggtg gccagcaggg cgcggccgtg ggccagcacg
    18721 acggggtcgt tgtcgacgta gaccaccgag gcgctgcggt cgaagcgctg cgcgatctgg
    18781 tgcgtgtttt ccgcggtcgg cagccccgat ccgcagtcaa gatactggcg aatcttgacg
    18841 tgcccggcca gatgccgcat gacgcgcgtg aggaagttgc ggttggccca cgccaattcg
    18901 gcaaccccgg ggtgaaccct cattgccgcg tcgaggactt cacggtcgac cgcgtagttc
    18961 gttttcccac cgagggcggc gtcgtagacg cgggcaatac tggcccggtt ggggtcgacg
    19021 ccaaccggga caacgctcgg cgagatgtcg tatggagatg tcacgctgta cctcactgga
    19081 agcggcattg ggtcccaagc cgcaccaccc tatcgagaca tctgttgcca ggtactcagg
    19141 cgcggaaaaa agtactggca gaccgaacag ccaccagccg tcgagggtgg gcctatccct
    19201 cgtaacgggc ccgtgggtgc gacgtcgcgc cgcattggcg gccacaccag accggcgacg
    19261 gtcaggcatc actatcattc ttttcgcgag tcataggaat tgttttttta tccgagatgt
    19321 ggtcgcctcc tcgtcgaggg tgccgttgcg gcggcgtggt tacgctgtcc cggtgaggtt
    19381 gcgacgcgag aaaactgcac gtcctacata tcggccaaaa agcgcgcgac cgtagaaatt
    19441 cagttatttc ctattatgat gcccgtcatt atgaattatt cagccccagt gacgattgcg
    19501 tgcgagatgg cggtcacgca ggtcggagca aagtggatac cgatgctgct gaagacggcc
    19561 gaagcgggaa aggtttccta cctcacccgt gacggtcgcg cgcacgccgc cgtggttccg
    19621 gttgcggtcg gccgcgccta cgaagaacag gccggactgt ccgactccgt ccgggccgag
    19681 atcgcggccg ccgtcgaccg cgcccgtacc gagatcacca ccgtcctcgc gcgcttggac
    19741 gaggaggtct gcggtcaccg gcttcccgcg gcagccgatc tccccgaaga catcccgccg
    19801 cgtgtcggcg agcctgacgt cgacgtgatc atctcgcgtg agaacggtga cgtcgagatc
    19861 gtcccggcgg cggaaacgcc gcgccccgac gaagaatccg ccccaggcgc cacgtgggtc
    19921 ggcgcggacg atccgctgct ggtgactctg caagagcaag tgtgcggacg ctggggtttc
    19981 caggcgatcc cgtggactcg gatccaaagc gcagccgaac accggggcgt gaggctgacc
    20041 tcccgcgcac atctgcaccg cgagctacgc agaatcctcg gcgatggtgc tccggagccg
    20101 atcaagcagg ctcgctcctg gtgctacgta acgatcgaac tatgggcggc gatcaacgcg
    20161 gccttgaccc accacggcca gccgctcacc taccaccggc cttacccggc cgtgcaggct
    20221 ttcgtggacc tgcttcccgc gatgctcgcc gcgtgcgagg gccgggacac ggcaccacgg
    20281 caggacgaga tcgccggagc gatacgtgcg gcggcgggag tccccgtccc cgccaccacc
    20341 gcgtcccggc tgggatgggt ggctcagcac taccaccacc atcggtgccc atggatcgac
    20401 accctcggcg gcaagccacc ccgaacgtag atccggtgct ggtgtcgagc gcggtgtgtg
    20461 gaacccggcc ggtgtgtggt gaggtcaggc ttcgtgcccg ctgaacgtgg gtgccgcgcc
    20521 gaggtattcg acgcgatacc ggaacccgcg cccctggcca tcatccatcg tgacgtggtc
    20581 ggcgtagaca tccacggtga tggaaccgtc ggcgtccgtg tcgacgtagg actgccaggt
    20641 gagatcacct tcgatcaccc cgtcctcggc gctgaaagcc agccgggcca cgtcgatcgg
    20701 gtcggtgata tcggggatgt ccgcgctcat gtcacgactg tatgaccatg ctcagattgc
    20761 acaccaacca gatacgccgg gctgcgaacc ggaagtggca tccgaggcgc accgacatcg
    20821 ccctggcccg cttcaccgtg atccccggcg cgggggatcg gcgaagcccg cggtcagcga
    20881 gctagcatag ctagcatggt gctgttcggt ggcaagccac catgcgagga tggtgtcatg
    20941 cccagcgagc atcgtgaacc cgccctgact gtccggccgc cggccgacct caagcgcgac
    21001 gctcaggcca cactggccga acgcgggctg caaatgcgcg cgttcgtggt ggcctgcctg
    21061 gccgcactaa ttaacgaccc cgaacgattc ctcgcgacat tgagaccgca ctggccggac
    21121 aagaagccac atcttggcgg cagagcggcg tcgaaacggg aacagtaaga gcccgtttgc
    21181 aaacaccccg gatcgtgtcc tcagtggttg tcggggaggc gtgcgatcct cgccgcgtgg
    21241 gtaatgagca tccggacctg atcgacctcg acgacggcga aatgttcgag tgggtggctg
    21301 aacccgccgg aggcggggag gcggggtatg cgaacacaga tgatcacgat ttcgcctggc
    21361 cacgtcatgt tctggaagag ggccggcgca tcgcggtgat gcgtgaggtg gcaccggccg
    21421 agctgaaacg actgcaccag gtgcgcgagg acgacgatcc ggaataccac cggtagagcc
    21481 ttgtttcgct cttcctcctc ggtcgtgggc tggtgaggtt gtgggggacg ttcgatggcg
    21541 tggacccggt tgtgctctgg tggtcgggtt cgaccgcgtc cgacgaggtg ttccagccac
    21601 agcagctacc cgccggaccg atgttgttcg cgatcgcctg tgcgacgaac aaggcggact
    21661 gcgcccagta gcactatgcc gggggcagcc atggtgtccc gtggtgcgcc tccgcgccga
    21721 actcatcgca catcgggcgg ttcgcctccc ctgaagtctt taccagagtg gcgataggcc
    21781 ctactgtggg caggttcttt ctccagaatg gtgtggcctc ctgtgtaggc gggggccaca
    21841 ctattctggg tcgctgccgg gtctccctgg aggctttctc gcgtttcggc atgagacgta
    21901 gccagggcag atgacacctc cgactgtgcc gatgtcgagt atggccggag atcctggccg
    21961 cgcaccgtgg ttaggcccgg tgggccaggc gcagcaggag ttcggcggtg tcgtcgagtt
    22021 cgtcggcgcg gtcacgtagg ttctgggcgc gctcgcggag acggcttgcg gcttggcggg
    22081 cgtgtgtcac atcggcctcg tgcgtgggcg tggccgtttc cggtgtcgcc gctgtgtcca
    22141 tggtggacga tgcttcaacc atgggtgcga tgtcggttgc gagggctgcg cggatcctgt
    22201 ccagtcgacc gggaccgact ccgtttaccg cgcgcagggc gtcgtctggg catgctctga
    22261 cttcctcggc ccatacgaat ccgtgccggt ccaggctttt gtagccggtg agatgaccgc
    22321 gctcgtcgag tgcgcggaac gcgtcacggt agtagtgcag tggtgtgcgg gtgtcgggca
    22381 tggggtgcag ggaccagccc gcgacagtcc cggcggcgta ttcggctcgc aggcgctcgg
    22441 ccatctcgct ggcgccgatc acatgcagca cacggtgcgg tcttatccgg cagactttgg
    22501 cctgtcccca gcgtccgccg ggctcgccgg cggtttccca cccgc
//
