LOCUS       NZ_CP016353            23463 bp    DNA     circular CON 03-MAY-2024
DEFINITION  Prauserella marina strain DSM 45268 chromosome, complete genome.
ACCESSION   NZ_CP016353
VERSION     NZ_CP016353.1
KEYWORDS    RefSeq.
SOURCE      Prauserella marina
  ORGANISM  Prauserella marina
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Prauserella.
REFERENCE   1  (bases 1 to 6851918)
  AUTHORS   Ruckert,C., Albersmeier,A., Jiang,C.-L., Jiang,Y., Kalinowski,J.,
            Winkler,A. and Zotchev,S.B.
  TITLE     Complete genome sequence of Prauserella marina DSM 45268, isolated
            from ocean sediment of the South China Sea
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6851918)
  AUTHORS   Ruckert,C., Albersmeier,A., Jiang,C.-L., Jiang,Y., Kalinowski,J.,
            Winkler,A. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUL-2016) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 33.7x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002240355.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 02:59:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,595
            CDSs (total)                      :: 6,536
            Genes (coding)                    :: 6,497
            CDSs (with protein)               :: 6,497
            Genes (RNA)                       :: 59
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 39
            CDSs (without protein)            :: 39
            Pseudo Genes (ambiguous residues) :: 0 of 39
            Pseudo Genes (frameshifted)       :: 14 of 39
            Pseudo Genes (incomplete)         :: 31 of 39
            Pseudo Genes (internal stop)      :: 1 of 39
            Pseudo Genes (multiple problems)  :: 6 of 39
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:50:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5221317
            Orig. end                         :: 5244780
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP016353.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23463
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="16"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23463
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23463
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13463](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13463
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(180..197)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.63"
                     /tool="antismash"
     gene            complement(235..753)
                     /locus_tag="BAY61_RS23935"
                     /old_locus_tag="BAY61_23790"
     CDS             complement(235..753)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS23935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_23790"
                     /product="hypothetical protein"
                     /protein_id="WP_091807392.1"
                     /transl_table=11
                     /translation="MRRLLGAVIIANILAGALVLRIPNAPAELAAAAPPRQCDWNTEYE
                     RTIKELGEDPRDVVRVAGIARKGQAYLDAHMIGINPTTPCDMVSSVIRHEWAHVQQGRL
                     AGGLDAAWRKYGDRLEIVADCTSWLLGSKHTPYRQQRIDDHFPGCTAADLADARELLGF
                     RSPADVSVR"
     misc_feature    complement(819..839)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
     gene            1465..2463
                     /locus_tag="BAY61_RS23940"
                     /old_locus_tag="BAY61_23795"
     CDS             1465..2463
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024753.4"
                     /locus_tag="BAY61_RS23940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23795"
                     /product="PQQ-binding-like beta-propeller repeat protein"
                     /protein_id="WP_091807390.1"
                     /transl_table=11
                     /translation="MFEIRWERQLHQAGTDTGIAVTTGGYVVLHERRTRLVCLDSATGS
                     HRWDVPVGTWPRALAVAGEHCYALPQNTSRLLCFDLETGHRVWSTELDSTTGHLVVSGD
                     AVLVGGWRGYTSPRVVDRATGELRWQTNDRQPTVRPIATDGGFLFGEPGGSAVRLLDRR
                     DGTELVAWSLPHPLIDTDNKATFTSAGSDRFLTRCGSRTVADIRPSRGTVREFLVTDHD
                     LAVSAPVHVGGLLWLRERRAGFTVARLTGDCLPYRVDVGQPLLDQVVAVETGFVVASMT
                     GILFHLDFDGRVTERVTVSRRITALRALSSAHVLVATKGTLLAVGVGPNHG"
     gene            complement(2677..3441)
                     /locus_tag="BAY61_RS23945"
                     /old_locus_tag="BAY61_23800"
     CDS             complement(2677..3441)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637653.1"
                     /locus_tag="BAY61_RS23945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23800"
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_091807388.1"
                     /transl_table=11
                     /translation="MAGQALIDHGRFLEALGYECELLIESSHATPPDLPVPLSPGWTVG
                     EVLRHVGSMYRQTLGWLVDGALPREWQRDPAPGQTVESYVREGFVDLQEVLAWHDPGER
                     AATWWPADPTYGFWARRMAHETTIHRYDVEDAARMPHAEIADDFAIDGIDEALALWFSH
                     RLPMLGLSGTRGSSVAVRSGGHTWIARAGPEETVAWHCSDREVEHADAVVSGSPVIVYL
                     WLWGRRWLTEIHSDGDADAVGQLWALLRLATK"
     gene            complement(3441..4076)
                     /locus_tag="BAY61_RS23950"
                     /old_locus_tag="BAY61_23805"
     CDS             complement(3441..4076)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005465742.1"
                     /locus_tag="BAY61_RS23950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23805"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_170140214.1"
                     /transl_table=11
                     /translation="MSLVFAARNGPTAPRGFGGAGDHGDPVARPGQGQAAGRVAPGRAG
                     EVRNPASHAAPAGQSALPIEVRPPAPPAAVSLLNQARHGVAEAGRESDAAHRFISAYLS
                     ALRAAAAILAARGRPHRGRARPESVWTLLASAAPELAQWAAFFAANSARRAAAQAGNSR
                     HITADSADELLRNAREFVALAQRAVHPRPAGAGNQCVNPPRMPRQRRR"
     misc_feature    4189..4204
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: strong, score: 27.38"
                     /tool="antismash"
     misc_feature    complement(4190..4203)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 24.78"
                     /tool="antismash"
     gene            4311..4856
                     /locus_tag="BAY61_RS23955"
                     /old_locus_tag="BAY61_23810"
     CDS             4311..4856
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019816154.1"
                     /locus_tag="BAY61_RS23955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23810"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_091807387.1"
                     /transl_table=11
                     /translation="MNTLDHPAVAKVSAALVEAGHVAAAEGIRILPSEVRTAVQAAEAL
                     GIEVGAIANSLIFRASFPRTDGTHGTEDAPVLALTSGAHRADTDTLAALLGATSVGKAD
                     PDFVKRHTGQVIGGVAPVGHLGPIRTLVDTALRDYDVVWAAAGHAKSVFPTTFEDLVTL
                     TGGLAADVASPAGQDVPR"
     gene            4853..5428
                     /locus_tag="BAY61_RS23960"
                     /old_locus_tag="BAY61_23815"
     CDS             4853..5428
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064527.1"
                     /locus_tag="BAY61_RS23960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23815"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_091807385.1"
                     /transl_table=11
                     /translation="MTAMSSGYQRLVELSRDEFRARLREALNLYVAAMNYPPETADQRM
                     PMWLTHALREGWRCVGALDADGALVGLAYGYRGSQGQWWHEQVRRGLTGEDGEQAAQRW
                     LSDYFELTEIHVRPDRQGKGTGEDLLRGLVEDVSQENVLLSTPEGTSRAWKLYRRLGFV
                     DVLRDYCFAGDPRPFAILGRSLPLDQRD"
     misc_feature    5571..5585
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.29"
                     /tool="antismash"
     gene            5634..6254
                     /locus_tag="BAY61_RS23965"
                     /old_locus_tag="BAY61_23820"
     CDS             5634..6254
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020671606.1"
                     /locus_tag="BAY61_RS23965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23820"
                     /product="AAA family ATPase"
                     /protein_id="WP_091807384.1"
                     /transl_table=11
                     /translation="MNCPISDQLCLRLDRRALVVVAGLPGAGKSTLLRGLDAPPTVVVL
                     DTDQLRTRLRAFFGPGIAYGWYRPLVHLLQILRLLFHAIRAKGPVVAHDPATGAVARCA
                     FVLLGALSLRERHLLWIDCSVTEALAGQHKRGRVLLSWSFRRHARNATGTRDRIDAGRL
                     PFGWHTATLTDRAKASKGLRLEIDEPAGAGIRRRQADHRRGRR"
     misc_feature    5703..5705
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6233..7144)
                     /locus_tag="BAY61_RS23970"
                     /old_locus_tag="BAY61_23825"
     CDS             complement(6233..7144)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005440152.1"
                     /locus_tag="BAY61_RS23970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23825"
                     /product="EamA family transporter"
                     /protein_id="WP_091807382.1"
                     /transl_table=11
                     /translation="MSVLSSARVRAGSISLVVAGVLWGTGGLAGSILASEAGLHSLAVA
                     AYRLLLGGAVAVLFLGLTGRLGGIGVAAPTKPVVRRVLAAGVLLAVFQAFYFASVTLTS
                     VSIATMTTIGSAPVFVAIGGALVDRRWPNPATLLAIAGAIAGLVLLTWSPQETGESWTL
                     LAGVLAALVSGCGFATLTLVTRKEVAGLDPLRTTAFGCVVGGILLLPAAAWFGMALPLR
                     VEVVAVAAYLAVVPTALAYAAYFRGLRDSPAVLAALSALLEPLTAALLAAVVLGDRLGV
                     LGWCGAALLAASIAAGYRRPRR"
     gene            complement(7368..9038)
                     /locus_tag="BAY61_RS23975"
                     /old_locus_tag="BAY61_23830"
     CDS             complement(7368..9038)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020419643.1"
                     /locus_tag="BAY61_RS23975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23830"
                     /product="DUF885 domain-containing protein"
                     /protein_id="WP_091807381.1"
                     /transl_table=11
                     /translation="MRVHEISDRYVDDFAAAHPCVATTVGISDYDSQLTDYSPEGHAAR
                     ASIAKRALRDLAEAEPADEGERVAKAVFTERIGLEVELHEAGLDVASLNVIESPVQEVR
                     SVFDLMPQDTEQHWDNIAARMAAVPSALDGVRASLLAAADAGRPAALRQVGKVAEQAEV
                     WAGLTGETGFFDSAVQQANGVPESLRERLRQAAATAQEAYAELAGFLRAELAPRAATKD
                     AVGEDVYRLWSRYFVGSELDLREAYEWGWAEFARVEREALEVAARIKPGATLAEAAAAL
                     DADERYHVRGHAAFERWMRELSDEALDSLRGKHFDIPEALMGLDCRIAPPGGGVGAYYT
                     SPNEDFSRPGTMWWSVPPDKDFFSTWREVSTVYHEGVPGHHLQLGTAVHQSATLNKFQR
                     LLGFTSGHGEGWALYAERLMRDLGYLSDDGNLLGMLDAHLFRAARVVIDIGMHLELEIP
                     AGTGFHEGERWTPELGLEFMLTRTITDADHVRDEIDRYLGWPGQAPAYKLGERLWLRAR
                     EDAQLRQGSSFDLKDFHTKALRMGNMGLDTLSDQLAKLA"
     gene            complement(9056..9940)
                     /locus_tag="BAY61_RS23980"
                     /old_locus_tag="BAY61_23835"
     CDS             complement(9056..9940)
                     /EC_number="1.5.1.20"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0006555 - methionine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332694.1"
                     /locus_tag="BAY61_RS23980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23835"
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="WP_091807379.1"
                     /transl_table=11
                     /translation="MTSVIERMRGERPVFSIEFFPPRDETDEAVMWRAIRDLEQLDPAY
                     VSITYGAGGTSRDGTIRSIARVATETTLVPMAHLTAVDHSVAELRNVIGWYAAVGVRNI
                     LALRGDPPGDPYGEWARHPEGLGYAEELVALIRSLGDFCVGVSAFPYGHPRSPDLATDT
                     KHLVRKFNAGADFGIAQLFFEADDFLRLRDRVAATGCDALVLPGIMPLTTPRTLAKTIE
                     LSGAKAPSALLDRLEPLKDDPKAFRAEGLDVVTELGQRLLDEGVPSLHFYTFNRSKATR
                     DLVGRLGLVPARA"
     misc_feature    9954..9971
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.15"
                     /tool="antismash"
     gene            10001..11110
                     /locus_tag="BAY61_RS23985"
                     /old_locus_tag="BAY61_23840"
     CDS             10001..11110
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020644799.1"
                     /locus_tag="BAY61_RS23985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23840"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_091807377.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 8.6e-48, bitscore:
                     161.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDPVPATVPDYDADLPAHVERALAEFLSGAGESIGSREPTFAPA
                     TSALREFVLGGGKRLRPTFAWWAWRGAGGDPAGDDAPGVIQVAASLELIQACALIHDDV
                     LDSSDSRRGSPTVHVAFTRRHADEGWLGSPESFGLAAAVLIGDLALAWADDMFADAPLP
                     SSTLRAARPAWRAMRTEVLAGQYLDVRTQATGDATVEAAMRVARLKTAAYTVQRPLHLG
                     AALAGADTGLVERLLAFGGDLGVAFQLRDDLLGVFGDPSVTGKPAGDDLREGKRTLLVA
                     LGLHHANERGKVTEHDTIASAIGNADLGTSDVERVRAALDDLGAVEEVERRIDELTESA
                     LASLRLASLDEPAATQLTALAAKATKRAY"
     gene            11110..12588
                     /gene="crtI"
                     /locus_tag="BAY61_RS23990"
                     /old_locus_tag="BAY61_23845"
     CDS             11110..12588
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637666.1"
                     /locus_tag="BAY61_RS23990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23845"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_091807375.1"
                     /sec_met_domain="DAO (E-value: 3.2e-21, bitscore: 74.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVRGGENVAVVGGGLAGLSAALHLLGAGRQVTVFEQEPRPGGR
                     AGGFAASGRHGDVIDSGASVLTMPEYAEEAFAAVGVRMADLLTLRKLDPAYRAHFADGS
                     SIRLYTEADAMEEEIRRVAGPAEAEGYRRLRRWLTELYAVQRDRFIGSNFDSPFDLLRP
                     ELVKLAALGGFGRLGPKIGSFLRDERVRRLFSFQSLYAGLDPARALGAYGVISYMDTVG
                     GVYYPVGGMSRVAEAMAKAVELAGGQVRYSSRVAWLERVGHRVRAVRTAEGQRSECDAV
                     VLATELTGAYRLLGIRPRRALPLRFAPSAFVLHGNSARGWSELDHHTIFFGRAWSGTFD
                     EIIRQGKLMSDPSLLVTNPTRSEPGLSFSGRELISVLAPAPNTRAAGIDWPSVGPAYRD
                     ELLRNLEKRGLPGFAGDVEVTDTVTPADWARKGLGAGTPFSLAHTFGQTGPFRPANLVR
                     GAENVVLAGCGTTPGVGIPPVLISGRLAATRITG"
     gene            12588..13463
                     /locus_tag="BAY61_RS23995"
                     /old_locus_tag="BAY61_23850"
     CDS             12588..13463
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018686266.1"
                     /locus_tag="BAY61_RS23995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23850"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_091807373.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.2e-106,
                     bitscore: 352.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.3e-64,
                     bitscore: 216.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELATAYATCRRINARHGRTFFLATRLLPARARPAAHALYGFARS
                     VDELVDNPRDGSDPAAMLDACSRALDRVYARGKPLTDPVLLAFADTVGRYGLERELFDA
                     FLHSMKLDLSVREYATFTELAEYTHGSAEVIGLQMLPVLGTVVPHHEAAPYAAALGEAF
                     QLTNFLRDVGEDLERGRLYLPTEELAAYGVERQRLEWAWHTGGTDRGITRALAALVARN
                     RAVYRRAKPGIPLLRKESRSCVRTALTLYEGILDEIVAADYNVLGGRVAVPRRRRFTVA
                     GTAILTRLWT"
     gene            13460..14248
                     /locus_tag="BAY61_RS24000"
                     /old_locus_tag="BAY61_23855"
     CDS             13460..14248
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332686.1"
                     /locus_tag="BAY61_RS24000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23855"
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_091807371.1"
                     /transl_table=11
                     /translation="MTTAANRPVRIGLQLQPQHADYAAIRRAASEAEELGVDIVFNWDH
                     FYPLYGDPVGKHFECWTMLGAWAESTTRVEIGALVTCNSYRNPELLADMARTVDHISGG
                     RLILGIGSGWFEKDYTEYGYEFGTAGGRLDALAESLPRIEKRLAELNPAPTRKIPVLIG
                     GGGEKKTLRLVAEHADIWHGFGDVEIASRKVRILDQHCADVGRDPAEIERSVGVRGNPE
                     DSGDGLLNAGITMFTVAEGGPDYDLSTLRKWIAWRDAQQS"
     gene            complement(14283..14831)
                     /locus_tag="BAY61_RS24005"
                     /old_locus_tag="BAY61_23860"
     CDS             complement(14283..14831)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637669.1"
                     /locus_tag="BAY61_RS24005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23860"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_091807370.1"
                     /transl_table=11
                     /translation="MMVGEDRIPGGSARAAAQRAVELMDVLLRERPTVELVTDVLVTHG
                     EKEPLGLTAADVGELRAAAHALRAVFAAEGVAEAAAVLNDLLAANAAPPRLTSHGGEHP
                     WHLHIDADDDGPWGRWLVTSSCLAFAVLLTDRQRPPGGLCASESCGRPFVDLGGGSPRR
                     YCSTRCATRERVAAHRKRG"
     gene            14855..16069
                     /locus_tag="BAY61_RS24010"
                     /old_locus_tag="BAY61_23865"
     CDS             14855..16069
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156488.1"
                     /locus_tag="BAY61_RS24010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23865"
                     /product="MFS transporter"
                     /protein_id="WP_091807368.1"
                     /transl_table=11
                     /translation="MSSRYSLGGYLAGATSARVGDEMSGPALLLVGLAATGSVTTASVL
                     LTALTATAALGGPVLGALLDRSARPGRVLALTLAGYATGLAIVLTSVGHLPVAVVALVA
                     ALTGLLNPAVAGGWTAQLPRVVPSERFGRANGLDALTFGAASPAGPALAGLVATAAGAP
                     TAMIVAIVAVAASAPAAIRLPPPGAQRGKRGVLRTELATGFRAIVTNRPLLRATSTSMV
                     SFAGVGMFIVCAPLLGEQRFGSANTGALLLAALAAAAVSANAVLARKPGLLRPGTMLLG
                     STVLLCAGLLLTALTTSPVIVVGAVLLAGIGEGPQLTALFAIRHQHAPDGMRAQIFTTG
                     ASLKIAGFAAGTAVAGPLAAMSLPACLAVAAGFEALAALLFLCLPDTRRGRNERPRRPS
                     PERAV"
     gene            complement(16038..16406)
                     /locus_tag="BAY61_RS24015"
                     /old_locus_tag="BAY61_23870"
     CDS             complement(16038..16406)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657740.1"
                     /locus_tag="BAY61_RS24015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23870"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_091807366.1"
                     /transl_table=11
                     /translation="MSAIPIADDVLDAEVAVLQIGQVADVIGQSSNKVRQMLRDGQLIA
                     VRRDGDLVIPADFLGDGGAVKGLAGTITVLSDAGFSRTEMLRWLFAADETLPGVTPINA
                     LRTSHGTEVKRRAQAMAF"
     gene            16553..18562
                     /gene="pknB"
                     /locus_tag="BAY61_RS24020"
                     /old_locus_tag="BAY61_23875"
     CDS             16553..18562
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005445905.1"
                     /locus_tag="BAY61_RS24020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23875"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_091807364.1"
                     /sec_met_domain="Pkinase (E-value: 2.3e-45, bitscore:
                     153.5, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSEPSLAGALLDRRYRVDRLLAHGGMSSVYRGVDTRLDRPVAI
                     KIMDSRFADDRNFVDRFEREARSAARLHHPHVVAVHDQGFDTSAGHEDRRAFLVMELVD
                     GGTLRDLIDQRGALDVPLAITVAENVLSALAAAHGEGLVHRDVKPENVLIGRRGSAEGG
                     VVKVGDFGLVRAVASAGTTSTSVILGTVAYLSPEQVTSGSASERGDVYSTGILLYEMLT
                     GQVPYTGDTALSVAYRHVNDDVPAPSVLRPGIPPALDDLVLRATRRDPEARPADAGAFK
                     AELENVRAELGMAPVAVPVPSTPDDQASAVTVSGSTGRHAAPDFDAERTVPAIQAITST
                     AGPRGTQALPRGAVSRDQPAVSQEEPPPPEAELPARRGKVFPALWIAVGLLIVAGIGVG
                     IWWFTGGRYVDVPKVAGMETGQAEQLVRGAELTPRVTEARHNTVPSGTVIGTEPEAGSR
                     ALLGDEITIVVSLGKPVVPDIPAGATVEQAEQAIKAMQLEPRRDGNADQYSDQVPEGAV
                     ITVTPQPGNQANIGDQVTIVVSKGPPPTPVPSVAGMSRDEAFQALTDAGFEPFDAGEEF
                     GEGVAAGHVTRTDPAQGATLEDDKRVGVYVSNAIEVPSVMGRQIDEALQILGEAGLTSN
                     AEDHRGRFAFVVNQDPAPGSWVEKGTAVNLTLVP"
     gene            18629..19159
                     /locus_tag="BAY61_RS24025"
                     /old_locus_tag="BAY61_23880"
     CDS             18629..19159
                     /EC_number="3.1.1.106"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165995.1"
                     /locus_tag="BAY61_RS24025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23880"
                     /product="O-acetyl-ADP-ribose deacetylase"
                     /protein_id="WP_091807524.1"
                     /transl_table=11
                     /translation="MPRSNIRLIQGDITTQEVDVIVNAANSSLLGGGGVDGAIHRAGGP
                     DILAACERLRETTHPDGLPTGDAVATTAGRLPARWVIHTVGPVYSTNEDRSQLLASCYH
                     EALRVAEELGAQAIAFPAISAGIFRWPLDNAAKIAVDSVEAAGSAMSEVRFVLFNAEAY
                     VAFEQAIKGLAGR"
     misc_feature    18947..18949
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    19145..19147
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            19324..20643
                     /locus_tag="BAY61_RS24030"
                     /old_locus_tag="BAY61_23885"
     CDS             19324..20643
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155385.1"
                     /locus_tag="BAY61_RS24030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23885"
                     /product="wax ester/triacylglycerol synthase family
                     O-acyltransferase"
                     /protein_id="WP_091807362.1"
                     /transl_table=11
                     /translation="MPSDRLSALDIAFLCLEGEATPMHMGAVATFRPRGHVDPHRLRSL
                     LAKRAAVIPKLGRRVRSTWPMFGGAQWEKDPDFEAERHIDVHRLCDLYEPDPLAEFASH
                     WIAEPLDTNAPLWNMQIVTGLPGDEFAVLMKFHHALTDGAGAVEVGFGLLDDVAIPVQR
                     EVADGPRTPASPLDVLRSGASTAIGQAAESAGIARDVLRAARPYPISPTATVNSTSRKL
                     GFVKIDLADIRYIRKAHGGTTNDVVLAVLAGALRDWMINRGQRADARSLRALVPVSLRG
                     RDARNNGGNVLSGYLCELPVELDDPVDRLAAIRHSMDRNKKAGPSRGAGAIPILANRLP
                     AGIHRLATRMAGMAAPLLFDTVVTNVPLPSRPMTLDGARLRGVYPIVPLAPHQSVGIAV
                     SSYRNTLHIGLQVNGAAVPDIGSLSDAVTKSVAGLYQRCG"
     gene            complement(20659..22050)
                     /locus_tag="BAY61_RS24035"
                     /old_locus_tag="BAY61_23890"
     CDS             complement(20659..22050)
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005445908.1"
                     /locus_tag="BAY61_RS24035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_23890"
                     /product="3-deoxy-7-phosphoheptulonate synthase class II"
                     /protein_id="WP_091807360.1"
                     /transl_table=11
                     /translation="MNWTVDVPIDTLPSLPPLPAELRDRLDAALTRPAAQQPEWPDGDA
                     VARVRAVLESVPPITVPAEIDRLRDRLAMVARGEAFLLQGGDCAETFESNTEPHIRANL
                     RTLLQMAVVLTYGASLPVVKVGRIAGQYAKPRSNSTDALGLPVYRGDIVNSLAAEPALR
                     VPDPGRMIRAYANAGAAMNLMRALTGAGMADLAQVHDWNKDFVRTSPAGERYEALASEI
                     DRGLRFMSACGVTDSSLHSTEIFASHEALLLDYERAMLRLDRPAEADAKLYNLSSHFLW
                     IGERTRQLDGAHIAFAELLANPIGLKIGPTTTPEQAVEYVQRLDPRHEPGRLTLISRMG
                     NGKVREVLPAIVEKVESSGHKVIWQCDPMHGNTHESSNGYKTRHFDRIVDEVQGFFEVH
                     NKLGTYPGGIHVELTGEDVTECLGGAQEISDLDLGGRYETACDPRLNTQQSLELAFLVA
                     EMLRA"
     misc_feature    22522..22537
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.74"
                     /tool="antismash"
ORIGIN
        1 cgcgaagccg ccaggtgttg gacgtgcggc ctccgcccaa cacatccggg ctgccgtcgg
       61 gcaggacgga gtagccggtg gatcgggctg cgcgcgggtc catgacctca cgctccctcg
      121 gtcttgttgc cggtcggcgg caccggtgtt tcgccctggt caagcgatcg ccatggtagg
      181 caacaacgtc gaaacatccg ccgtgcgcgg cggcggacgc gggagaccgg tccgctaccg
      241 cacggacacg tcggcgggcg accggaagcc gagcagttct ctcgcgtcgg cgagatcggc
      301 cgcggtacaa ccggggaaat gatcgtcgat gcgctgttgc cggtaggggg tgtgtttcga
      361 cccgagcaac caggacgtgc agtcggccac gatctcaagc cggtcgccgt actttctcca
      421 cgcggcgtcg agccctccgg ccaggcggcc ctgctgcacg tgtgcccact cgtggcggat
      481 cacgctcgac accatgtcgc acggggtcgt cggattgatc ccgatcatgt gcgcgtcgag
      541 gtacgcctgc cctttccggg cgatcccggc gacgcggacg acgtcgcggg gatcctcgcc
      601 gagttccttg atggtgcgtt cgtactcggt gttccagtca cactgccgtg gaggtgcggc
      661 ggcggcgagt tcggcggggg cgttggggat ccgcagcacc agcgcgccag caaggatgtt
      721 cgcgatgatg accgcgccaa gaagccgtcg caccctctgt cctcaccccg tggtcggcgc
      781 gctcgacggc ggtgagcgat cgagcgaatg cccagtgtca cagatcgtaa gctatgcgta
      841 atcaccccaa cacggggagg gagcattggc ggcctccgtg ggcaattcgg acagtgctac
      901 cgggcgggac tgtcgaataa cggttgccag agcaggaccg gtgaggcagg gctctgccgg
      961 gacaaggccc tggctgggag gcggggcccc tcctgccggt cggcgattcc agtcagcggc
     1021 gcttccgatc gcgcttcttg tcagcggcgc ttccgatcgc gcttcttgtc agcggcgctt
     1081 ctggtcaggc gggcttcgtg tcaggcaacg cttctgatca caacggttcg ggccggggca
     1141 gcggtttcgg tccggcggca cttccggccg ggcaacgcct tgtgccgacg acggttccgg
     1201 ccgtcgcttc cggccgagca gcggtttcgg tccgtcaacg acgttggtcg gcaacgctcc
     1261 agtcggctac cgcttccgcc gggcggcggt tccaccatcg ttgggtgccg tctcgtcggc
     1321 accggtccgg cgaacgtcga tccactgtgg acaaggttcc cagggacccg ccgcgcttca
     1381 ccgagccgcg cggcaggtct cggcccgcga cccgagcgcg caacgcggtt gcgtctcccc
     1441 cgccctgctt gatggactac gggggtgttc gagatccgct gggagcggca gttgcaccaa
     1501 gctggtaccg acaccggtat cgcggtcacc accggcggat acgtggtgct ccacgagcgg
     1561 cgtaccaggc tggtgtgtct tgattccgct accggctcgc atcgctggga cgtgcccgtc
     1621 ggcacctggc caagggcact cgccgtcgcc ggcgagcact gctacgcgct tcctcagaac
     1681 accagccggt tgctgtgctt cgacctggaa accggacacc gcgtgtggag tacggaactc
     1741 gattcgacca ccgggcatct cgtggtgtcc ggcgacgccg tcctcgtggg cggctggcgt
     1801 ggctacacgt ccccgcgcgt ggtggaccgc gcgacgggag agcttcggtg gcagacgaac
     1861 gaccggcagc ccaccgtgcg accgatcgcc acggacggcg gtttcctctt cggcgaaccc
     1921 ggcggttcgg cggtgaggtt gctcgaccgg cgggacggca cggaactggt ggcgtggtca
     1981 ttgccgcacc cgctcatcga caccgacaac aaggcgacgt tcaccagcgc cggaagcgac
     2041 cggttcttga cgcgatgcgg ttctcgtacg gtggcagaca tccggccctc gcgaggtacg
     2101 gtgcgagaat tccttgtcac cgaccatgat ctcgctgtat cggcaccggt tcacgtcggc
     2161 ggcctgcttt ggctgcgcga acgccgggcg ggcttcacgg tcgcccgcct caccggcgat
     2221 tgcctgccgt accgagtcga tgtcgggcaa ccccttctcg atcaggtcgt cgccgtcgag
     2281 accgggtttg tcgtcgcctc catgacggga atcctgtttc acctcgattt cgacggccgg
     2341 gtcaccgaac gtgtcacggt gtcgcgcagg atcacggcgc tgcgcgctct ttcctccgcc
     2401 catgtgctgg tggcgacgaa gggaaccttg ctggctgtcg gggtcggacc gaaccacgga
     2461 tagtgcctgc cccggagtcc acattggttc gtcaccgtct gatgtggcca gccggccggt
     2521 cggctccggc agcacgcccc gacgacggcg acccgggtgg tggccggatc attccgttcc
     2581 ggccaccacg gtcaccacgg tcaccatggg cacgagcagc acgaccgagg tgcgaatccg
     2641 atcgacggga cgttgcttcc ccacaagccc cggtgatcat tttgtcgcca acctcagcaa
     2701 cgcccacaac tgtcccaccg cgtcggcgtc gccgtcagag tggatttcgg tgagccatct
     2761 cctgccccac aaccacaaat aaacgatgac cgggctcccc gacaccaccg cgtcggcgtg
     2821 ctcgacctct cggtccgaac aatgccacgc gacggtctct tccggccccg ccctcgctat
     2881 ccaggtgtgc cctccggacc gcaccgcgac cgaacttccg cgggtaccgc tcaatccgag
     2941 catcgggagc cggtggctga accacaaagc cagcgcctcg tcgatgccgt cgatggcgaa
     3001 gtcgtcggcg atctcggcgt gtggcatccg cgcggcgtcc tcgacgtcgt accggtggat
     3061 ggtggtctcg tgtgccatgc gccgagccca gaaaccatag gtgggatcgg caggccacca
     3121 ggtggccgcc cgctcgccag gatcgtgcca ggcaagcacc tcttgcagat cgacgaaacc
     3181 ctcgcgcaca tagctctcga cggtctgtcc cggcgccgga tcgcgttgcc actcccgcgg
     3241 cagggcaccg tcgaccaacc agcccagcgt ctgccggtac atgctgccga catgccggag
     3301 tacctcgccg accgtccacc ccggactcag tggaacgggt agatccggtg gtgtcgcgtg
     3361 agaactctcg ataagcagtt cacattcgta gccgagcgcc tcaaggaacc tcccgtggtc
     3421 gatcagcgcc tgccccgcca tcatctcctc cgttgccggg gcatccgtgg cggattgacg
     3481 cactgattgc ctgcccctgc cggtcgtggg tggacggcac gctgtgccag cgcgacgaac
     3541 tcacgcgcgt tgcgcaacaa ctcgtcggcc gaatcagcgg tgatgtgccg ggagttaccc
     3601 gcctgcgccg ctgccctcct tgccgaattc gcggcgaaga acgcggccca ctgcgccagc
     3661 tccggtgccg ccgaagcgag cagcgtccat acgctctccg gccttgccct tccccggtgc
     3721 ggcctgcccc tcgcggcgag gatggcggcg gcggcacgca acgccgaaag gtaggcggag
     3781 atgaaccggt gggcggcatc ggattccctg cccgcctcgg caacaccgtg cctggcctgg
     3841 ttcagcaacg acaccgccgc gggcggagcc ggtggcctca cctcgatcgg caacgcggac
     3901 tgaccggccg gagcggcatg gctcgccggg tttctcacct cacccgccct gccaggggcc
     3961 acccttccgg ctgcctgccc ttgtcccggc ctcgcgaccg gatcgccgtg atctccggcc
     4021 cctccgaaac cgcgcggtgc cgtcggaccg ttgcgcgccg cgaacacgag cgacatggcc
     4081 cacctccctc ttcgagccga tccggagcac ttccggcggc cccggcgcgc agatgcttcc
     4141 cccatccaca cgccgggaac cccggaccgg agaacactcc accggttgtc gaacgtatgt
     4201 tcgaacatct ccagagtagc ttgcgaccgc gacgggctca agcctgggtg ctggggctat
     4261 tggagcgatc tgcgtcgcat cggcaggcca taccgtgatc tcataccggt atgaacaccc
     4321 tcgatcaccc cgccgtcgcc aaggtctccg ccgcgctcgt cgaggcaggc catgtcgcgg
     4381 cggccgaagg catccgcatc ctgccttcgg aagtacgtac agccgttcag gccgcggaag
     4441 ccctcggtat cgaggtcggc gccatcgcca acagcctcat cttccgcgcc tccttcccgc
     4501 gcaccgacgg cacccacggc acagaggacg cgcccgtgct cgcgctgacc tcgggggcgc
     4561 accgggccga cacggacacg ctcgccgcgc tgctcggcgc cacctccgtc ggcaaggcgg
     4621 accccgattt cgtcaagcgg cacaccggcc aggtgatcgg cggcgtcgcc ccggtgggtc
     4681 atctcggccc gatcagaact ctcgtcgaca ccgcgcttcg cgactacgac gtggtctggg
     4741 ccgccgcggg gcacgcgaaa tcggtctttc ccaccacttt cgaggatctg gtcaccctca
     4801 ccggcgggct cgcggcggac gtcgcgtcac cggcaggaca ggacgtgcca cgatgaccgc
     4861 gatgtcctcc ggataccagc gactcgtcga gctctcccgc gacgaattcc gcgccaggct
     4921 gcgcgaagcg ctcaacctgt acgtggccgc catgaactac ccgccggaaa cagcggacca
     4981 gcgcatgccg atgtggctca cccacgcgct gcgcgagggc tggcgctgtg tcggcgcgct
     5041 ggacgccgac ggcgcgctcg tcggcctcgc ctacggctac cggggaagcc agggacagtg
     5101 gtggcacgag caggtgcgcc gcggcctgac cggcgaggac ggcgagcagg ccgcgcaacg
     5161 ctggctgagc gactacttcg agctgaccga gatccacgtc cggcccgacc ggcagggcaa
     5221 aggcactgga gaagatctgc tgcgcgggct ggtcgaggac gtgtcgcagg aaaacgtgct
     5281 gctgtcgact ccggaaggca ccagcagggc ctggaagctg taccggcgac tgggtttcgt
     5341 cgacgtactg cgggactact gcttcgcggg cgacccgcgt ccgttcgcca ttctcggccg
     5401 ctcgctcccg ctcgaccaac gggactaaca ggactaacgc gaccaacgag accagcccgg
     5461 caacgagcca ctaggtccta tccgccttct ctcgtgggat gacgacatca tctgggatcg
     5521 agatctcaat tcgcggtcct cgccaacctg cggcttcgac cggaacgctg tgaaatccct
     5581 gttctcaccc gaatccccgg aacgcgccgt ggcaccggca cgttggcgct tgcgtgaact
     5641 gccccatctc ggatcaactc tgccttcgac tcgaccggcg agcgctcgtc gtagtcgccg
     5701 gattacccgg cgcaggcaag agcacactgc tgcgcggcct cgacgcgccc cctaccgtgg
     5761 tcgtactcga caccgaccag ctcagaacga gactcagggc attcttcgga cccggcatcg
     5821 cctacggctg gtaccggccg ctcgtgcatc tgttgcagat actccggctg ctgttccacg
     5881 cgatccgcgc gaagggaccc gtcgtggcgc acgatccggc gaccggggcc gtggcacggt
     5941 gcgctttcgt cctgctcggc gcgctgtccc ttcgcgagcg gcacctgctg tggatcgact
     6001 gctcggtcac cgaagctctc gcggggcaac acaaacgcgg aagagtcctg ttgagctggt
     6061 cgttcagaag gcacgcccgc aacgcgacgg gtacccgcga ccgcatcgac gccggtcgtc
     6121 tcccgttcgg ctggcacacc gcgacgctca ccgacagggc gaaggcgagc aaggggctcc
     6181 ggctggagat cgacgaaccc gccggcgccg gaatccggcg ccggcaggcg gatcaccgcc
     6241 ggggccgccg gtaaccggcc gcgatggacg ccgcgagcaa cgcggctccg caccaaccga
     6301 gaacaccgag ccggtcaccc agcacaacgg cggcgagcag agccgccgtc aacggttcga
     6361 gcagtgccga cagcgcagcg agcaccgcgg gcgaatcgcg aagaccgcgg aagtaggcgg
     6421 catacgccag cgctgtcggc accaccgcga ggtaggcggc caccgcgacg acctccaccc
     6481 gcaacggcag tgccatgccg aaccaggcgg cggcgggaag cagcaggatc ccgccgacga
     6541 cacacccgaa agccgtggtg cgcaagggat cgaggccggc gacctccttg cgggtgacca
     6601 gggtcagcgt ggcgaacccg caaccggaga caagcgcggc cagcacaccg gcgagcaggg
     6661 tccagctttc tcccgtctcc tgcggcgacc aggtgagcag cacgagcccc gcgatggcac
     6721 cagcgatggc gagcagggtc gcggggttcg gccacctgcg gtcgacgagc gccccgccga
     6781 tggccacgaa gaccggcgcg ctgccgatcg tggtcatggt cgcgatgctc accgaggtca
     6841 aggtgaccga ggcgaaatag aacgcctgga acacggcgag cagcactccg gcggcgagca
     6901 ccctgcgcac cacgggcttt gtcggcgctg ccacgccgat cccgccgagc cgccccgtga
     6961 gaccgaggaa cagcacggcg accgcgcccc cgagcagcag ccggtaggct gcgaccgcga
     7021 gcgaatggag cccggcctcc gaggcaagta tggaaccggc gagcccgccg gttccccaca
     7081 gcacccccgc gacgacgagg ctgatcgaac ccgcgcgaac ccgcgcggag gaaagtacgg
     7141 acatgcgaga agcacgctcc aacgtcgaag tggaaaggac gacgacggcg cggggcgcga
     7201 cggtaaaacg gaagaaagac agcaccgtac ggccgatgcc gcacagtggt cagtcgttca
     7261 caccccgctc agcggcgggg cggcggggtg acgaaaagaa ctcgcttcac gacggcgagc
     7321 ataaccggcc gcgcgggaac atcgacgcgc ggccggcccc gcgaggctca ggcgagcttc
     7381 gcgagctgat cgctcagggt gtcgagcccc atgttgccca tccgcaacgc cttcgtatgg
     7441 aagtccttga ggtcgaagga acttccctgc cgcagctggg catcctccct cgcccgcagc
     7501 cacaaacgct cccccagctt gtaggcgggg gcttgccccg gccagccgag gtagcggtcg
     7561 atctcgtccc gcacgtgatc ggcgtcggtg atggtcctgg tgagcatgaa ctccagcccg
     7621 agttccggag tccagcgctc accctcgtgg aacccggtgc ccgccgggat ctccagttcg
     7681 aggtgcatcc cgatgtcgat gacgacgcga gccgccctga acaaatgcgc gtcgagcatg
     7741 ccgagcaggt tgccgtcgtc ggagaggtag ccgagatccc gcatcagccg ctcggcgtac
     7801 agcgcccagc cttcgccgtg gcccgacgtg aaaccgagca gccgctggaa cttgttcagg
     7861 gtcgccgact ggtggacggc cgttccgagc tggagatggt ggccgggaac gccctcgtgg
     7921 tagacggtgc tgacctcgcg ccaggtcgag aagaagtcct tgtcaggagg aaccgaccac
     7981 cacatggttc ccggccttga gaagtcctcg ttcggcgagg tgtagtacgc gccgacccca
     8041 ccgcctggcg gcgcgatgcg gcagtcgagt cccatcagcg cttcggggat gtcgaaatgc
     8101 ttgccacgca acgaatccag cgcctcgtcg gagagctcgc gcatccaccg ctcgaaggcg
     8161 gcatggccgc gtacgtggta gcgctcgtcc gcgtcgagcg cggccgcggc ttcggccagc
     8221 gtcgcacccg gtttgatgcg cgcggcgacc tccagtgctt cccgctcgac gcgggcgaac
     8281 tcggcccagc cccattcgta ggcttcccgc aggtccagct cggagccgac gaagtaccgc
     8341 gaccacaacc ggtagacgtc ctcaccgacg gcgtccttcg tcgcggccct cggagccagt
     8401 tcggctcgca ggaatccggc cagctcggcg tatgcctcct gggctgtggc cgccgcctgc
     8461 cgcaaccgct ccctcaggct ttccggaacg ccgttcgcct gctggacggc cgaatcgaag
     8521 aacccggtct ccccggtcag gcccgcccac acctcagcct gttccgcgac cttgccgacc
     8581 tggcgcagcg cggcggggcg gcccgcgtcg gccgcggcga gcagggatgc cctcacgccg
     8641 tcgagagccg atggcacggc ggccatcctg gccgcgatgt tgtcccagtg ttgctccgtg
     8701 tcctggggca tgaggtcgaa caccgagcgc acctcttgga cggggctctc gatgacgttg
     8761 agcgaggcga cgtcgagacc tgcctcgtgc agctcgacct ccagcccgat ccgctccgtg
     8821 aagacggctt tggccacgcg ctcgccctcg tcggccggct cggcttcggc gagatcacgc
     8881 aaggctcgct tcgcgatcga cgcacgcgcc gcgtgccctt ccggcgagta gtcggtgagc
     8941 tgactgtcgt agtcggaaat tcctaccgtc gtcgccacgc acgggtgagc ggcggcgaaa
     9001 tcgtcgacgt accgatcgct gatctcgtgg acacgcatga gcgcacgcta cccggtcagg
     9061 cccgtgccgg gaccagtccc aatctcccga cgaggtcgcg cgtggctttc gagcgattga
     9121 aggtgtagaa gtgcagcgag ggcacgccct cgtcgagcag ccgctgtccg agctcggtaa
     9181 ccacgtcgag cccctccgcc cgaaacgctt tcgggtcgtc cttgagcggc tccagccggt
     9241 caagcagagc cgacggcgct ttcgccccgg aaagctcgat ggtcttggcg agcgtgcgcg
     9301 gcgtggtcag cggcatgatc ccgggcagga ccagcgcgtc gcagcccgtc gcggcgacgc
     9361 ggtcgcgcag ccggaggaag tcgtcggcct cgaagaagag ctgggcgatg ccgaagtcgg
     9421 ctccggcgtt gaacttccga acgaggtgct tggtgtcggt agccagatca ggcgaacgcg
     9481 ggtggccgta gggaaacgcg gagacaccga cgcagaagtc gccgagtgag cggatgagcg
     9541 cgacgagttc ctccgcgtag cccagtcctt ccgggtgccg cgcccactcg ccgtagggat
     9601 cgcctggggg gtcgccgcgc agcgccagta tgttccgcac gccgacggcg gcgtaccagc
     9661 cgatgacgtt gcgtagttcg gcgacggagt ggtcgacggc ggtgagatgc gccatcggta
     9721 ccagcgtcgt ttcggtggcg accctcgcga tgctccgaat cgtgccgtcc ctgctcgtcc
     9781 cccctgcgcc ataggtaatg gagacgtagg cggggtcgag ttgttcgagg tccctgatcg
     9841 cgcgccacat gacggcctcg tcggtttcgt cgcgtggagg gaagaactca atggagaaca
     9901 cggggcgctc gccacgcatc cgctcgatca ccgacgtcat aggcgtatgt tacgtgctac
     9961 gtccgtgtta cccgccgcgt cggcctggga cgatgggggc atgaacgacc ccgtccccgc
    10021 cacagtcccc gattacgacg cggacctgcc cgcccatgtg gagcgtgcgc tggccgagtt
    10081 cctgagcggg gcaggcgaat ccatcggcag cagagaaccc acgttcgccc ccgcgacctc
    10141 ggcactgcgc gagttcgtgc tcggcggggg aaaacggctg cgtcccacgt tcgcatggtg
    10201 ggcgtggcgg ggcgccggtg gcgaccccgc cggcgatgac gcgccggggg tcattcaggt
    10261 cgcggccagt cttgagctga tacaggcgtg tgcgctgatt cacgacgacg tcctcgactc
    10321 gtccgactcc cggcgcggtt caccgaccgt gcacgtcgcc ttcacgaggc gccatgccga
    10381 cgaggggtgg ctcgggtcac cggaatcctt cgggctcgcc gcggcggtgc tcatcggcga
    10441 cctcgcgctc gcctgggccg acgacatgtt cgccgacgcg ccccttccct cctcgacact
    10501 gcgggcggcg aggcccgcct ggcgggcgat gcggaccgag gtgctggccg gtcagtatct
    10561 cgacgtgcgc acgcaggcaa cgggcgacgc caccgtcgaa gcggcgatgc gggtggcaag
    10621 gctcaagacg gcggcctaca ccgtgcagcg gccgctgcat ctcggcgccg cgcttgccgg
    10681 ggccgatacc gggctcgtcg agcgactgct cgccttcggt ggtgatctcg gcgtcgcgtt
    10741 ccagctcagg gacgacctgc tcggagtatt cggcgaccct tccgtcaccg ggaaacccgc
    10801 cggcgacgat ctgcgggagg gcaagcggac gctgctcgtc gcgctcggcc ttcaccacgc
    10861 gaacgagcgg ggcaaggtga ccgagcacga cacgatcgcc tccgcgatcg gcaacgccga
    10921 tctcggtacg tccgatgtgg agcgggtgcg ggccgcgctg gacgacctcg gagccgtcga
    10981 ggaggtggag cgcaggatcg acgagctcac cgagtcggcg ctcgcgtctc tgcggctggc
    11041 ctcgctcgac gaacccgcgg cgacacaact cacggcactc gccgccaagg cgacgaagcg
    11101 agcctactga tgcgcaccgt gcgcggtggc gagaacgtcg ccgtcgtcgg tggcgggctc
    11161 gccggtctct cggccgcgct gcacctgctc ggcgccggaa ggcaggtcac ggtgttcgag
    11221 caggaaccga gaccgggcgg aagggcgggt ggtttcgccg cgagcggacg acacggcgac
    11281 gtgatcgaca gtggagcaag cgtgctgacg atgccggagt acgctgagga ggcgttcgcg
    11341 gccgtcggcg tgcggatggc cgacctgctg accctgcgca aactcgatcc cgcctaccgc
    11401 gcgcacttcg ccgacggcag cagcatccgg ctctacaccg aggccgatgc catggaggag
    11461 gagatccgcc gcgtcgcggg ccccgcggag gccgagggct accgccggct ccgccgctgg
    11521 ctcaccgagt tgtacgcggt gcagcgcgac cggttcatcg gttcgaactt cgactcgccg
    11581 ttcgatctac tcaggccgga gctggtgaaa ttggccgcgc tgggcggttt cggcagactc
    11641 ggaccgaaaa tcggaagctt cctgcgggac gagcgggtgc ggaggctgtt ctcgttccaa
    11701 tcgctctacg cgggactcga tccggcgcga gcactcggcg cctacggcgt catttcctat
    11761 atggacaccg tcggcggcgt gtactacccg gtgggcggca tgtcccgggt cgccgaagcc
    11821 atggcgaaag ccgtcgagct ggccggtggc caggtgcggt actcgtcgcg ggtggcctgg
    11881 cttgagcgcg tcggtcaccg ggtccgcgcg gtccgtaccg ctgaggggca gcgaagcgaa
    11941 tgcgacgccg tcgtgctcgc gacggaactc accggcgcct accggctact gggtatccgg
    12001 ccgcgccgcg cgctgccgtt gcgcttcgcg ccgtcggctt tcgtactgca cggcaacagc
    12061 gcgagggggt ggagcgaact cgaccaccac acgatcttct tcggcagggc gtggtccggc
    12121 acgttcgacg agatcatcag gcagggcaag ctgatgagcg atccctcgct gctggtgacc
    12181 aaccccaccc ggtcggagcc agggctttcc ttctccggcc gcgaactgat ttcggtgctc
    12241 gcccccgcgc ccaacacgcg ggcggccggg atcgactggc cgagcgtcgg ccccgcctat
    12301 cgcgacgaat tgttgcgaaa tctggaaaaa cgcggattgc cgggtttcgc gggcgatgtc
    12361 gaggtcaccg acaccgtgac gccggccgac tgggcacgaa agggtctcgg cgcggggacc
    12421 ccattctcac tggcccacac cttcggccaa accggaccgt tccgccccgc gaatctcgtg
    12481 cggggagccg agaacgtggt actcgccggt tgcgggacca cccccggcgt cggcatcccg
    12541 cccgtgttga tctcgggaag gctcgcggcg acgaggatca ccggctgatg gagctggcga
    12601 cggcatacgc gacgtgcagg cgcatcaacg cgcggcacgg gcggacgttc tttctcgcga
    12661 ccaggctcct tcccgcgcgc gcgagaccgg cggcacacgc gctgtacggc ttcgcccgct
    12721 ccgtcgacga actcgtcgac aatccgcgcg acggcagcga ccccgccgcg atgctcgatg
    12781 cctgttcccg tgcgctcgac cgggtttacg ctcgcggaaa gccccttacc gatccggtac
    12841 tgcttgcctt cgccgacacg gtcgggcgct acggcctcga aagagaactc ttcgacgcct
    12901 tcctgcattc gatgaagctg gacctttcgg tacgcgagta cgcgacgttc accgaactcg
    12961 ccgagtacac gcacggctcg gccgaggtga tcggcctgca aatgcttccc gtccttggca
    13021 cggtcgtccc gcaccacgaa gccgccccct acgcggccgc gctcggggaa gcgttccagc
    13081 tcaccaactt cctgcgcgac gtcggtgagg atcttgagcg gggcaggctc taccttccga
    13141 cggaagaact cgccgcgtac ggcgtcgaaa ggcaacggct cgaatgggcg tggcacacgg
    13201 gaggcaccga ccgcgggatc acgagggcgc tcgcggctct cgtcgcgcgc aacagggcgg
    13261 tgtatcggag ggcgaaaccg ggtattccgc tgctgcgcaa ggaatcccgc tcgtgcgtac
    13321 ggacggcgct gaccctgtac gaaggcatcc tcgacgagat cgtcgccgcg gactacaacg
    13381 tcctcggcgg gcgggtcgcc gtgccgagaa ggagacgctt cacggtcgcg ggaaccgcga
    13441 tcctcactag gctgtggaca tgacgacagc agccaaccgg cccgtccgaa tcggactcca
    13501 gctccagccg cagcacgccg actacgccgc catccggcgc gccgcgtcgg aggccgagga
    13561 actcggcgtc gacatcgtgt tcaactggga ccacttctac ccgctctacg gcgatcccgt
    13621 cggcaagcac ttcgagtgct ggaccatgct gggcgcgtgg gctgagtcga cgacacgggt
    13681 cgagatcggc gcgctcgtga cgtgcaacag ctaccgcaat ccggaactac tcgccgacat
    13741 ggctcgcacc gtcgaccaca tcagcggggg aaggctcatc ctcggcatcg ggtccggctg
    13801 gttcgagaag gactacacgg agtacggcta cgagttcggc acggccggcg gcaggctcga
    13861 cgcgctcgcc gaatcgctgc cgaggatcga gaagaggctc gccgagctca accctgcccc
    13921 cacccgcaag atcccggtgc tgatcggcgg tggcggcgag aagaagacgc tcaggctggt
    13981 cgccgagcac gccgacatct ggcacgggtt cggcgacgtc gagatcgcct cccgcaaggt
    14041 gcggatcctc gaccagcact gcgcggacgt cggaagggac cccgccgaga tcgagcgctc
    14101 cgtcggcgtg cgcggcaacc ccgaggattc cggcgacggc ctgctgaatg cgggcatcac
    14161 catgttcacc gtcgcggaag gcggacccga ctacgacctg agcacgctgc gcaagtggat
    14221 cgcgtggcgc gacgcccagc agagctgagt tcctgagcag ggcgggcacc ggtccgccct
    14281 gctcagccgc gcttgcggtg tgccgcgacc cgttccctcg tcgcacagcg cgtcgagcag
    14341 tacctgcgag gactcccgcc accgagatcg acgaacggcc ttccgcacga ctccgaggcg
    14401 cacaaccctc ccggtggccg ctgccggtcg gtgagcagca cggcgaaggc gagacaggac
    14461 gaggtcacca gccacctgcc ccacgggccg tcgtcgtccg cgtcgatgtg caggtgccaa
    14521 gggtgttcgc cgccgtggct ggtcagccgt ggtggtgccg cgttggccgc gagcaggtcg
    14581 ttgaggacgg cggcggcctc ggccacgccc tcggcggcga acacggccct cagcgcgtgc
    14641 gcggcggccc gcaattcgcc gacgtcggcg gcggtgaggc cgagcggctc cttctccccg
    14701 tgcgtcacca gcacgtcggt gaccagttcg acggtgggcc gttcccgcag cagcacatcc
    14761 atcagttcga cggcgcgctg ggccgcggca cgcgccgaac caccgggaat tctgtcctcg
    14821 ccgaccatca tgtcgtcagt gtaacgtctc ctttgtgtca agccgttaca gtctgggtgg
    14881 ctatctcgcc ggagccacct ccgccagggt gggcgacgag atgtccggcc cagcgctgct
    14941 cctcgtggga ctggccgcga cggggtcggt gaccaccgcg tccgtcctgc tcacggcgtt
    15001 gaccgcgacg gcggcgctcg gcggaccggt actcggcgct ctgctcgatc gcagcgcgag
    15061 gccaggccgg gtactcgcgc tgaccctcgc gggctacgcg accgggctcg cgatcgtgct
    15121 gacgagcgtc ggtcaccttc ccgtcgccgt cgtcgcgctc gtcgccgccc tcaccggcct
    15181 gctcaacccc gccgtggcag gcggctggac cgcccagttg cctcgcgtcg tgccatcgga
    15241 gcggttcggc agggccaacg gcctcgacgc gctgaccttc ggcgcggcga gtcccgcggg
    15301 acccgccctg gcggggctcg tggcgaccgc ggcaggcgcg ccaaccgcca tgatcgtggc
    15361 catcgtggcg gtggccgcct cggctccggc cgcgatccgg ctccctccgc ctggcgctca
    15421 gcgagggaaa cgcggggtgc tgcgcacgga attggcgacc gggttccgcg ccatcgtcac
    15481 caaccgcccg ctgctgcgag ccaccagcac gtcgatggtg tccttcgcgg gcgtcggcat
    15541 gttcatcgtg tgcgcgccgc tgctcggcga gcaacggttc ggctcggcga acaccggcgc
    15601 gttgttgctc gccgcgctcg ccgccgccgc ggtgtcggcc aacgcggtgc tggcccgcaa
    15661 acccggcctg ctgcgccccg gcaccatgct gctcggcagc accgtgctgc tctgcgccgg
    15721 tctgctgctc accgcactga ccacctcacc ggtgatcgtc gtcggtgccg tgctgctcgc
    15781 cggcatcggc gaaggaccac aactcaccgc gctgttcgcc atccggcatc agcacgcgcc
    15841 ggatggcatg cgggcacaga tcttcacgac gggagccagc ctgaagatcg ccgggttcgc
    15901 agcgggaacc gccgtcgcgg gcccgctcgc ggcgatgtcg cttccggcat gcctcgccgt
    15961 cgccgcggga ttcgaggcac tcgcggctct gctgttcctg tgcctgccgg ataccaggcg
    16021 cgggaggaac gaaaggccta gaaggccatc gcctgagcgc gccgtttgac ctcggtgccg
    16081 tgactcgtgc gcagggcgtt gatcggggtg acgcccggca gggtttcgtc ggccgcgaac
    16141 aaccagcgca gcatctccgt gcggctgaat cccgcgtcgg agagcaccgt gatggtgcct
    16201 gccagcccct tgacggcccc accgtcgccg aggaaatcgg cggggatgac caggtcaccg
    16261 tcccggcgga cggcaatgag ctgaccgtcc ctcagcatct ggcggacttt gttcgacgac
    16321 tggccgatga catcggcgac ctggccgatc tgcaacaccg cgacctcggc atccagcaca
    16381 tcgtcagcga tagggatcgc actcacgcct actaccttgc cacatcactc ctcgggctac
    16441 gcgggcgttg ttcccggcgg cccagcgggc acgggctcgg ggagcaggcg aggaagcgta
    16501 ctgagggcac tgtggacggg ggcaactcca cccgaccgta ggatcgggcg ctgtgacccg
    16561 ctcggaaccc agcctcgcag gcgcactgct cgaccggcga taccgtgtcg accggctgct
    16621 cgcgcacggt ggcatgtcgt cggtgtaccg cggcgtcgac accagactgg accgccccgt
    16681 cgccatcaag atcatggact cccggttcgc cgacgaccgc aatttcgtcg accggttcga
    16741 aagggaagcg cgctccgctg cccgactgca ccacccgcac gtcgtcgccg tccacgacca
    16801 gggcttcgac acctcggccg gccacgagga ccgcagggcc ttcctcgtca tggagctcgt
    16861 cgacggcggc accctgcgcg atctcatcga ccagcggggt gccctcgacg tcccgctcgc
    16921 gatcaccgtc gccgagaacg tgctgtccgc tctcgccgcc gcgcacggcg agggcctggt
    16981 gcacagggac gtgaaaccgg agaacgtgct catcggccgc agaggcagcg ccgaaggcgg
    17041 tgttgtcaag gtcggggact tcgggctggt cagggcggtc gcgagcgcgg gaacgacgag
    17101 tacgagcgtc atcctcggca cggtggccta cctctcgccg gagcaggtca cctccggttc
    17161 ggcaagcgaa cgcggcgacg tctattcgac gggcatcctg ctctacgaga tgctgaccgg
    17221 gcaggttccc tacaccggtg acaccgcgct gtcggtggcg taccggcacg tgaacgacga
    17281 cgtgccggcc ccgagtgtcc tgcgccccgg tatcccgccc gcactcgacg acctcgtgtt
    17341 gcgagccacc cggcgcgacc ccgaggcccg ccccgccgac gcgggcgcgt tcaaggccga
    17401 gctggagaac gtgcgcgccg aactgggcat ggcgccggtc gccgttcccg tgccgtcgac
    17461 acccgacgac caggcgagcg cggtcaccgt ctcgggaagc accggaaggc acgccgcgcc
    17521 cgatttcgac gcggagcgca cggttccggc catccaggcg atcacctcga cggcgggccc
    17581 gaggggcacc caggcgctgc cgaggggagc ggtttccagg gaccagcctg ccgtctcgca
    17641 ggaagagcct ccgccgcccg aagcggagct gcccgcgcgg cgaggaaagg tgtttcccgc
    17701 gctgtggatc gccgttggcc tgctcatcgt cgccgggatc ggcgtcggca tctggtggtt
    17761 caccggcgga aggtacgtcg acgtgccgaa ggtcgccggc atggaaaccg gtcaggccga
    17821 acaactcgtc aggggagctg agctgacccc ccgggtcacc gaggccaggc acaacacggt
    17881 gccgagcgga accgtcatcg gcaccgaacc ggaagccggt tcgcgcgcgc tgctcggcga
    17941 cgagatcacc atcgtcgtct cgctcggcaa accggtggta cccgacattc cggcaggcgc
    18001 gacggtcgaa caggccgagc aggcgatcaa ggccatgcag ctcgaaccac gacgagacgg
    18061 caacgccgac cagtacagcg accaggtgcc ggaaggcgcg gtcatcacgg tgaccccgca
    18121 gccgggaaac caggccaaca tcggcgacca ggtcaccatc gtcgtatcga aggggccacc
    18181 gccgacaccc gtgccctccg tcgccgggat gtcgagggac gaggcattcc aggcactcac
    18241 cgatgccgga ttcgaaccgt tcgacgcggg cgaggagttc ggcgagggcg tcgcggccgg
    18301 gcacgtcacc cgaaccgatc cggcgcaggg cgcgaccctc gaagacgaca agcgggtcgg
    18361 cgtctacgtg tccaacgcca tcgaggttcc ttcggtgatg ggaaggcaga tcgacgaagc
    18421 cctgcaaata ctcggcgaag cggggctgac gtcgaacgcc gaagatcacc ggggacggtt
    18481 cgccttcgtc gtcaaccagg atcccgcgcc gggaagctgg gtggagaagg gcacggccgt
    18541 caacctgacg ctcgttccgt gatctcgcca cgcggcacct ggtgagacgg aactgcggcg
    18601 gcccggcccc agtgccacac tcttgaccat gccacgctcg aacatccggc tgattcaggg
    18661 tgacatcacc acccaggagg tggatgtcat cgtcaacgcg gccaattcca gcctcctcgg
    18721 cggcggcggg gtcgacggtg ccatccaccg cgcgggagga ccggacatcc tcgccgcgtg
    18781 cgagcggctc agggaaacga ctcatcccga cgggctgccc accggcgacg ctgtcgccac
    18841 gacggcgggg cgcttgcccg ctcgatgggt tattcacacg gtcggtcccg tctactccac
    18901 aaacgaggat cgctcacagc tgttggcgtc ctgttaccac gaagcgttac gtgttgccga
    18961 agaactcggc gcccaagcga ttgcttttcc cgcgatatcg gctggaattt ttcgatggcc
    19021 cctcgacaac gcggcgaaaa tcgccgtaga ttcggtcgag gcggccggga gcgctatgag
    19081 cgaagtccgg ttcgttctgt tcaatgccga agcctatgtc gccttcgagc aagcgatcaa
    19141 aggattagcg ggccggtaac acggcgacca cgcatgcgtc atccgcacct ggtggactgg
    19201 aagaggaagt tgcgaaacgg cgacgcgtgg gatacccgag cgcggcgacg ccacggcgtc
    19261 gcatgcgtga attcgcaacc acaacagcaa ccgacgtagc gacgatttcc ggggagaccg
    19321 ccgatgccat cggaccggct gagcgcactg gacattgcct tcctgtgcct tgagggcgaa
    19381 gcgacgccca tgcacatggg cgcggtggcg acattccgcc ctcgcgggca cgtcgacccg
    19441 caccggctgc gttccctgct cgccaagcgc gccgcggtaa ttcccaaact gggaaggcgg
    19501 gtcaggtcga cgtggccgat gttcggcgga gcgcaatggg aaaaagaccc tgatttcgaa
    19561 gccgaacgtc acattgacgt ccaccggctt tgtgacctct acgaacccga tccgcttgcc
    19621 gaattcgcgt cacactggat cgccgaacca ctcgacacca acgctccatt gtggaacatg
    19681 cagatcgtga ccggacttcc cggcgacgag ttcgccgtgc tcatgaagtt ccaccacgcg
    19741 ctgaccgacg gggccggtgc ggtcgaagtc ggcttcggcc tcctcgacga cgtcgcgatc
    19801 ccggtccagc gcgaggtcgc ggacggtcct cggacgccgg cttcgccgct cgacgtcctc
    19861 cgttccggag cgtcgaccgc catcggccag gcagcggaat cggccggtat cgcccgcgac
    19921 gtcctgcgcg cggcgagacc ttatccgatc tcccccaccg cgacggtcaa ctcgacgagc
    19981 cgcaagctcg gcttcgtcaa aatcgacctc gccgacatca ggtacatccg gaaagcccac
    20041 ggcggtacga caaacgacgt cgtgctcgcc gtgctcgccg gagcactccg cgactggatg
    20101 atcaacagag gccagcgcgc cgacgcccgt tcgctgcgcg cgctggtccc ggtgagcctg
    20161 cggggaaggg acgcccgcaa caacggcgga aacgtactgt ccggctacct gtgcgaacta
    20221 cccgtcgaac tggacgaccc ggtcgaccgc ctcgccgcga tcaggcattc gatggaccgc
    20281 aacaagaagg ccggaccgag cagaggagcg ggcgcgatcc cgatactggc caacaggttg
    20341 cctgccggta tccaccggct ggcgaccagg atggcgggca tggcggcacc gctgcttttc
    20401 gacaccgtcg tcaccaacgt gccgctgccg agcaggccga tgacgctcga cggggcgagg
    20461 ctgcgcggcg tgtacccgat cgtcccgctc gcgccgcacc agtcggtggg catcgccgtc
    20521 tccagctacc gcaacacgct ccacatcgga ctacaggtca atggagccgc ggtacccgac
    20581 atcggctcgc tctccgacgc cgtgaccaaa tcggtggccg ggctctacca gcggtgcggc
    20641 tagcgagccc ctgcccgttc aggcccgcaa catctccgcg acgaggaacg ccagctcaag
    20701 cgactgctgc gtgttcagcc tggggtcgca agccgtctcg tacctgccgc cgaggtcgag
    20761 atcggaaatc tcctgtgcac cgccgaggca ttcggtgacg tcctcaccgg tcagctcgac
    20821 gtggatgccg ccggggtagg tgcccagctt gttgtgcacc tcgaaaaagc cctggacctc
    20881 gtcgacgatg cggtcgaagt gccttgtctt gtagccgttg gacgattcgt gggtgttgcc
    20941 gtgcatcggg tcgcactgcc agatgacctt gtgccccgag ctctcgacct tctccacgat
    21001 cgcgggcagc acctcgcgca ccttgccgtt gcccatcctg gagatcagcg tcagcctccc
    21061 cggttcgtgc cgggggtcca gccgctgcac gtactcgacg gcctgctcag gagtcgtcgt
    21121 cgggccgatc ttcaacccga tcgggttggc cagcagctcg gcgaaggcga tgtgcgcgcc
    21181 gtcgagctgc ctcgtgcgct cgccgatcca caggaaatgg gacgagaggt tgtacagctt
    21241 ggcgtcggct tcggccggcc ggtcgagacg cagcatcgcg cgctcgtagt cgagcagcag
    21301 cgcctcgtgg ctggcgaaga tctccgtcga atgcagcgaa ctgtccgtga cgccacaggc
    21361 cgacatgaac cgcaggcccc tgtcgatctc ggaggcgagc gcctcgtacc gctcaccggc
    21421 gggagaggtg cgcacgaagt ccttgttcca gtcgtgcacc tgcgcgaggt cggccatccc
    21481 ggcaccggtg agcgccctca tcaggttcat cgcggcaccc gcgttggcgt aggcgcggat
    21541 catcctgccg gggtccggaa cgcgcagcgc gggctcggcg gcgagcgagt tgacgatgtc
    21601 gcccctgtag acgggaaggc cgagggcgtc ggtggagttg gacctcggct tggcgtactg
    21661 accggcgatt ctgcccacct tcacgaccgg aaggctcgcg ccgtaggtca gcaccaccgc
    21721 catttgcagc agcgtgcgga ggttggccct gatgtgcggt tcggtgttgg actcgaaggt
    21781 ctccgcgcag tcaccgccct ggagcaggaa cgcttccccc ctggcgacca tcgcgagccg
    21841 gtcgcgcagc cggtcgatct cggccggaac cgtgatcgga ggcacactct ccagtaccgc
    21901 gcgcaccctc gcgacggcgt cgccgtcggg ccactccggc tgctgggccg caggccgcgt
    21961 cagtgccgcg tcgagccggt ctcgcagctc ggcaggcaac ggcggtagcg agggaagggt
    22021 gtcgatgggg acgtccacgg tccagttcac ccacccagca tacgaagccc cgccgagagt
    22081 cccgcgccga cgtgcgagca accaaacggc gcgcgctgga tcacgaccgg gcaccggtga
    22141 gagttgccgc tggtcgaggg cgcagtcagg acccgagcta ccccgaacgt ggagtcgcga
    22201 gcaccgcagc ggccgcccgc gacgtggccg gattcacccg gcacgggcag ccgtaccggt
    22261 cagaccaccg cgagcggcaa cgccgtcggg tgcaccggcg aaggcagatc cgaggctccg
    22321 gtgaggtagt ggtcgaccgc gtgcgcgacc gaacgtccct ccgcgatcgc ccacaccacg
    22381 agcgaggcac cccggtgcgc gtcgccgcac acgaaaacgc caggcgccgc cgtctgccaa
    22441 tcgggaccgc aggacaccgt gccacgcggt gtcagggaca acccgagatc atcgagcaac
    22501 cgcatgtgct cgacgccctc gaaaccgatc gcgaacaaca cgagatcggc cgggatttcc
    22561 tcgacctcct cgctcgtcgc aaccacctcg cggcggccgg tctcgctgtc cttctccacc
    22621 ctgacggtcc gcagttcgat cgccctcacc gcgccgtcct cgtcaccgac gaaccgcttg
    22681 accgcgaccg cgaaccgccg ttccccccgc tcctcgtgca ccgggtaggt gcgcaacaga
    22741 taaggccagg tcggccacgg cgacctctcg tcgtcgcgtg tggacggtgg ctgcgggtat
    22801 tggtcgagct gggtcaccga gagcgcgccc tggcggatcg ccgtgccgta gctgtcggca
    22861 ccggtgtccc cgccgccgat gatcacgacg tgcttgcctg ccgcgtcgat gtcagggggc
    22921 ccatcgccct cgcactgctt gttggcggga acgaggtgct ccatcgcgag atggattccg
    22981 gaaagctccc tgccatcggt ggtcgtgtcg tccctgcccc gcaaggcacc gacggcgagc
    23041 acgacggcgt cgaaccgttc cctcagttcc tccaccgtga cgtcgacgcc gacctcgcag
    23101 gcggtgacga acgtcgtgcc ctccctgcga agctgggcga gcctgcgatc gagaaccttc
    23161 ttctccatct tgaactcggg aatgccgtac cgcagcaggc cgccgagccg gtcgtcccgc
    23221 tcgaacaccg tcacctcatg cccggcgcga gtgagctgct gggcggcggc aagcccggcc
    23281 ggcccggacc cgacgacggc gacccgctgc cccgtcggca cctcggactg ctccggccgc
    23341 acgtagtcca gctcccacgc ccgcgccgcg atggtctcct cgacccgctt gatggccacc
    23401 ggcccgcccg aggcaggcga aatcgacaac acgcagcccg cctcacacgg cgcgggacac
    23461 aac
//
