LOCUS       NZ_CP016353            26005 bp    DNA     circular CON 03-MAY-2024
DEFINITION  Prauserella marina strain DSM 45268 chromosome, complete genome.
ACCESSION   NZ_CP016353
VERSION     NZ_CP016353.1
KEYWORDS    RefSeq.
SOURCE      Prauserella marina
  ORGANISM  Prauserella marina
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Prauserella.
REFERENCE   1  (bases 1 to 6851918)
  AUTHORS   Ruckert,C., Albersmeier,A., Jiang,C.-L., Jiang,Y., Kalinowski,J.,
            Winkler,A. and Zotchev,S.B.
  TITLE     Complete genome sequence of Prauserella marina DSM 45268, isolated
            from ocean sediment of the South China Sea
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6851918)
  AUTHORS   Ruckert,C., Albersmeier,A., Jiang,C.-L., Jiang,Y., Kalinowski,J.,
            Winkler,A. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUL-2016) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 33.7x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002240355.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 02:59:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,595
            CDSs (total)                      :: 6,536
            Genes (coding)                    :: 6,497
            CDSs (with protein)               :: 6,497
            Genes (RNA)                       :: 59
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 39
            CDSs (without protein)            :: 39
            Pseudo Genes (ambiguous residues) :: 0 of 39
            Pseudo Genes (frameshifted)       :: 14 of 39
            Pseudo Genes (incomplete)         :: 31 of 39
            Pseudo Genes (internal stop)      :: 1 of 39
            Pseudo Genes (multiple problems)  :: 6 of 39
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:50:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3017090
            Orig. end                         :: 3043095
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP016353.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26005
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="7"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26005
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26005
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16005](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16005
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(11..27)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.03"
                     /tool="antismash"
     misc_feature    complement(600..617)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: medium, score: 28.63"
                     /tool="antismash"
     misc_feature    789..803
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            complement(910..2184)
                     /locus_tag="BAY61_RS14070"
                     /old_locus_tag="BAY61_13995"
     CDS             complement(910..2184)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024808.4"
                     /locus_tag="BAY61_RS14070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_13995"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_091798065.1"
                     /transl_table=11
                     /translation="MKTARTAVLLVLLALLTQVSACTTAERVTIIGPWTGTEEAAFRAV
                     LDEFERETGIGYDYLGTRSLSPVLAADVQQGTPPDIAILSSPNELVNYQRQGALRQLPE
                     LEDELRSAYSPQWLQLAQAGTERPYAVVVKAALKGLVWFNPNVLTGPVPRTWNQLVSLT
                     DAAAAEGRTPWCMGMGAMSATGFPGSDWIEDILLRRYGPETYQRWVTGDLPWTAPEVRE
                     SWIAWGELILGDGAVHGGRGGSLLTNYTTANDTMFAADPGCFLEHQGSYVVNDYRSKGA
                     RFDFFPTPGPSGPGDAWLVSADLATMFRDTPAARELMRFLASAEGQRIWPEADRGAVFT
                     VRQDVAATTGSDAVTRNVARIISTAKVLCYDASDLMPTAVTNAFHRAALGYLADPGRLD
                     QLLAELERIRTGVSAQDWANVVCGR"
     gene            complement(2181..3329)
                     /locus_tag="BAY61_RS14075"
                     /old_locus_tag="BAY61_14000"
     CDS             complement(2181..3329)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS14075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_14000"
                     /product="hypothetical protein"
                     /protein_id="WP_091798068.1"
                     /transl_table=11
                     /translation="MGIPAQLGAAAIATVRPGDGKSTTARTLRLLRGWSLVLTVAVLAG
                     SVAAFAGVRSAIDTMRGRTTPAIISSASVYEALVHANTSAVTAFALGPGQLSGAGDFYQ
                     AQIGVASQNLAQVAEHNVAGSASRRELQLVQGLLVSYTSWMSQAELRFRTGDDSMAGAT
                     DVWYAAQLLHDADGILPHLSQLRAAQLDELDDQLARDWMHPGASAIWLIPVAALAVLLC
                     AAQVYHHRRFRRRLNPHLLAATGLLIAVAALPALTIPAQARAHHGANELREEITIWQQR
                     AHTAAAADRRAVAVLVTGHCQPDGCGDSVAEFAASPTGSAVPRGTADDQLAGTGADVTA
                     GFDRAALPQAVLWLIVAGAGGIAVLIITGFQRRITEYQGHPS"
     misc_feature    complement(2775..2777)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3329..5392)
                     /locus_tag="BAY61_RS14080"
                     /old_locus_tag="BAY61_14005"
     CDS             complement(3329..5392)
                     /EC_number="2.7.11.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF028228.4"
                     /locus_tag="BAY61_RS14080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14005"
                     /product="serine/threonine protein kinase"
                     /protein_id="WP_143021325.1"
                     /sec_met_domain="Pkinase (E-value: 1.6e-26, bitscore: 91.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRHPTRPNTTTLAPDRFASREATTEELGGDLLGFPRLPRYDTAG
                     AQLPFVEVPSPSGLVEGAPADPEPALAPGTVLAGKYEVIGGLAHGGLGWVYLAKDIELD
                     ELYVALKGMIDPSDTKLAEAERKTLTALNHPNIVRIFGFVLHRASAEREPDGYIVMEFV
                     NGHSLRELLGRLGAGEDVFGEPLLAEHVIGYAQELLDALHYLHGQGLLYCDLKPDNIMH
                     GGHRIKLIDLGATRKVGDDTTPLAMTRRYQVGDSELAQHGVTVRSDLHTLGVTLGELLA
                     VSDDDPAGETAFGVRSLRHVIDRATAPFAQRFVSAADMAGALDGVLREIQSLRDGEPRP
                     VPSALFAETPALFDVGLGAAPPLERWTAAPAEDYSPPPLDDGRPSPADIALMLPPPLPD
                     PADAGAGFLTEMRAPDARRRLGQLAGWVENNGHTVELSLAQCRAHLEVGAPERARSWLD
                     YATTTLGEDGEYDWRLGWHRGLLALTRSDILEAEAEFFSVHRALAGEAAPKLALGYCAE
                     HQGKPDVATDYYHAVWQRDRTQVSAAFSLARLRLAEYDRAGAVAVLDQVPAVSLHYYAA
                     RIATVRVFVGDLGEGPPTSTDLVNAFLRRPELNLEGDEENGGAGPARDRLDTEVYEAAL
                     HRAVKSGDGERRNAVGAQLEQCLRGLARQARDAESQGVLIDLANTVRPKTWF"
     gene            complement(5454..6215)
                     /locus_tag="BAY61_RS14085"
                     /old_locus_tag="BAY61_14010"
     CDS             complement(5454..6215)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020659919.1"
                     /locus_tag="BAY61_RS14085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14010"
                     /product="sigma 54 modulation/S30EA ribosomal C-terminal
                     domain-containing protein"
                     /protein_id="WP_245866078.1"
                     /transl_table=11
                     /translation="MSRQGDASVANGIVVHTRGEVLDGAKEYVRKQLTTFARRLPARLD
                     AARVKLTAFTKPSAPVPALAQANLQIEGRPVRAQVAAPFFTEAAGLLRARLKEQIAMLT
                     APRTGRPWDGAAPLGPATAKVTGRREIVRHKTYELTECAPGEATFTMDLMDYDFYLFTD
                     SETGEDSVVYRVGPTGYKLARLASLAPPAGPAAVPLTVNVHPVPHQTPAEAAGRLDETA
                     LPFTFFLDSTTSRGAVVYRRYDGHYGHLAPR"
     gene            complement(6308..6967)
                     /locus_tag="BAY61_RS14090"
                     /old_locus_tag="BAY61_14015"
     CDS             complement(6308..6967)
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680770.1"
                     /locus_tag="BAY61_RS14090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14015"
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="WP_091798074.1"
                     /transl_table=11
                     /translation="MQFENRADAGRELAGRLGYLSAHHPIVLGLPRGGAVVARQVADGL
                     GCALDVLLVQRVRAPERPELAVGAVGEGGVLVTNADLLREYRLSRQDMDLAVRTALAEL
                     DRRTELYRGDLPPLSVAGRTVVLVDDAIATGATVRAALRVLRGRQAGRVVLAVPVAPAD
                     VLEELAHNADHTVCPNPRVWMRAVGHWYRDFSPVSDEDVLPLLGRPRSVPSPAPDL"
     gene            7195..8109
                     /locus_tag="BAY61_RS14095"
                     /old_locus_tag="BAY61_14020"
     CDS             7195..8109
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016208 - AMP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009154294.1"
                     /locus_tag="BAY61_RS14095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14020"
                     /product="universal stress protein"
                     /protein_id="WP_091798943.1"
                     /transl_table=11
                     /translation="MGAEDAASGAVVVGVDGSESSGWAVDWAAALAAQRDLPVRIVHAY
                     GLIGRYYGAELAVPMNVLEAVDEDARGLVAAAAEQARGLAPGVEVTSEVFDEPPIPLLN
                     KLSAEAKMVVLGQSGLGGFAGMLAGSTALGVASHASAPVAIVRRREGGERPAEGPVVVG
                     VDGSQVSEQAVAVAFEEASFRGVPLVAVHAWMDVEYPIGFNKAREYFETGPVEQEENRV
                     LAERLAGWQEKYPDVPVERVVVRDKPRNQLLDRSREAQLVVVGSRGRGGFTGMLLGSTS
                     QALLHHAECPVVVARPVKGERAG"
     gene            8159..8758
                     /locus_tag="BAY61_RS14100"
                     /old_locus_tag="BAY61_14025"
     CDS             8159..8758
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS14100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_14025"
                     /product="hypothetical protein"
                     /protein_id="WP_091798077.1"
                     /transl_table=11
                     /translation="MWQSATLLARLWRRIHPGRNPLVRLSDRVESAALVAAVVIPLLAL
                     PFVAAVGSDSYAREIAVAQQQQRTRHEVEAVLLTDAPATQRNTGTAGTGPTVSARAEWS
                     LPDGSRRTGMVPARAAAPAGTTVEIWLDETGRPVPPPMSRGVIAWNAFAVSLTVWIGVV
                     LLSGLLFVALRHALDRGRYHRWQSEWSAFDRERHES"
     gene            complement(8830..9114)
                     /locus_tag="BAY61_RS14105"
                     /old_locus_tag="BAY61_14030"
     CDS             complement(8830..9114)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017982310.1"
                     /locus_tag="BAY61_RS14105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14030"
                     /product="dsRBD fold-containing protein"
                     /protein_id="WP_091798080.1"
                     /transl_table=11
                     /translation="MTYPAQWTMSIVLDENDGTTRARVRLGDDLGNHFDGIGLAYRGLD
                     VARVPQIAGELALARALNDLTEELLAAVAADIETELGGARLAAPVERVP"
     misc_feature    9331..9349
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 22.17"
                     /tool="antismash"
     misc_feature    complement(9552..9567)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.06"
                     /tool="antismash"
     gene            9600..9980
                     /locus_tag="BAY61_RS14110"
                     /old_locus_tag="BAY61_14035"
     CDS             9600..9980
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS14110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_14035"
                     /product="hypothetical protein"
                     /protein_id="WP_143021326.1"
                     /transl_table=11
                     /translation="MNAVAGMAGLLGPGRGVRRAGGAKGRPVISRTGNAVRGRAPRRRE
                     LPEVATLADNGGFDAPTIGAVAERDEADRMQSMQSLGELSPLEGARTAGRPPERAAPLD
                     HTANPQGVLALTGFPASCWRRD"
     gene            10001..10900
                     /gene="hpnC"
                     /locus_tag="BAY61_RS14115"
                     /old_locus_tag="BAY61_14040"
     CDS             10001..10900
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005457358.1"
                     /locus_tag="BAY61_RS14115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14040"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_091798086.1"
                     /sec_met_domain="phytoene_synt (E-value: 8e-41, bitscore:
                     138.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.3e-45,
                     bitscore: 153.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDRAVSAAGAPAAETFESADSVPALHGVLAKARSENFPVASWLL
                     PPAHRGHLLALYAFARMVDDIGDEAAGDRLRLLDAVSGDIARLFAGAAPTTKLYADLAA
                     TVHERGLPKEPFDRLIEANRQDQSVCRYRTFDDLLGYCALSADPVGRLVLGVFGADTPD
                     RRVLSDRICSALQVLEHCQDVAEDVRQGRIYLPLADLDLFGVTESDLFAERAGRPLRAL
                     IGYEVQRAVAMLDEGAPLVATLRGTARVAVAGYVAGGRATAVAIASARFDVLAGTPKPA
                     KTRTAAEWLRLLGKGGDR"
     gene            10897..11754
                     /locus_tag="BAY61_RS14120"
                     /old_locus_tag="BAY61_14045"
     CDS             10897..11754
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005465126.1"
                     /locus_tag="BAY61_RS14120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14045"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_091798089.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.9e-55, bitscore:
                     186.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 9.5e-65,
                     bitscore: 217.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTAEAYAECERITRGQARNFSYGIRLLPAPKRKALSAVYAFARR
                     IDDIGDGDLPSEQKLEALENARKQLHDLGGSGDDPVLTGLWHAAWRFELPLGAFDELIE
                     GCTADVVGTSYETFDELRHYCRCVAGSIGRLSLAVFGSPDRARDERIADDLGIALQLTN
                     ILRDVLEDRVAGRIYLPAEDLRAFGCTLDLTERAELADPEDALLPLLEYQAARAEEWYE
                     CGLRLLPLLDSRSRACCAAMAGIYHRLLRRMALRPRFVLRGRTSLPDWEKIAVAGRALA
                     GTSP"
     gene            11751..13088
                     /gene="hpnE"
                     /locus_tag="BAY61_RS14125"
                     /old_locus_tag="BAY61_14050"
     CDS             11751..13088
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009154300.1"
                     /locus_tag="BAY61_RS14125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14050"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_091798095.1"
                     /sec_met_domain="DAO (E-value: 1.7e-12, bitscore: 46.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAHVAVVGGGLAGLTAACDLSDRGVRVTLLEARNRLGGATFSFQ
                     RDGLTVDNGQHVLLRCCTEYRALLEKLGTADGIDLQRRFRMPVLTGGGAGAELARTGGP
                     APLHLAAGIARYAALPVTDRIRVFRAAAALRFLDPADPALDRLSFADWLGRHGQNDATL
                     RGLWNLIAVAALNCDASEASLALAVMVFRTALLDRADAADIGVPALPLSELHVDPAEKY
                     LLERGGYVRTRSPVRAIRRQGRGFTIRLDDEAIDVDGVVMAAPPDAAALVCPREAGLDP
                     DRLGKLGAAPIVNVHVVYERPVTDLPFAATVSPSSPVQWIFDRTGVAGLDSGQYLTVSL
                     SAAHRWLDTPVAELREIFLPELARLLPAAAGVPHRQFFVTRERRATFRQGPGTAALRPR
                     AATRLPGLALAGSWTATGWPDTMEGAVRSGHQAAGLIVEHIGGGSP"
     gene            13085..14092
                     /locus_tag="BAY61_RS14130"
                     /old_locus_tag="BAY61_14055"
     CDS             13085..14092
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005439219.1"
                     /locus_tag="BAY61_RS14130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14055"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_091798097.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.1e-61, bitscore:
                     207.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTLPAEVTATRTLVQPALREAVRSLQPAMRRVVSYHLGWTDEH
                     GQPADAGGGKALRPALALLAAQAVKAAPEAALPGAVAVELVHNFSLLHDDVMDGDVERR
                     HRPTVWRLFGTPAAILAGDALLTLAVDVLERAADPVATRCLTAAVQHLITGQSADVDFE
                     NRLDVGVGECLDMAAGKTGALMRCAAQVGALLGRGSPVAAGLLAEFGSNLGMAFQLVDD
                     LLGIWGSPEDTGKPVLADLRVRKKSVPVVAALNSGTEYGAALRELYRNPDPPTEEEVHT
                     MAELIERSGALAWTRERAHRYVGEAGTCLDRLAPPEPIHAALRDLTLFVVERDR"
     gene            14113..16005
                     /gene="shc"
                     /locus_tag="BAY61_RS14135"
                     /old_locus_tag="BAY61_14060"
     CDS             14113..16005
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421276.1"
                     /locus_tag="BAY61_RS14135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14060"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_245866213.1"
                     /sec_met_domain="T2TS (E-value: 1.2e-145, bitscore: 484.6,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATVSARAAEATERARHHLLSLQHEEGWWKGELETNVTMDAEDLM
                     LRQFVGIADDRLLAESARWIRSCQREDGTWANFYGGPADLSTTVEAYTALRMAGDPAGS
                     PHLRRAREFILDSGGIEATRVFTRIWLALFGEWSWDRLPVLPPELVLLPHWFPLNVYDW
                     ACWARQTVVPLTIVASSRPRRPLGVSVQELRTGKPVPEPDSPLTWAGAFQRLDSVLHIA
                     EKFPVKPLRRIALSTAEKWIVDRQEADGGWGGIQPPWVYSILALNLRGYSTRHPVLRKA
                     IEGLEGFTIRERTEEGWVRRLEACQSPVWDTALALTALLDSGLAPDDPALVKAADWVLR
                     EEIRSEGDWQVRRGDLAPSGWAFEFANDHYPDTDDTAEVILGMRRIDHPEPHRLREVLD
                     RAAAWTAGMQSKDGGWGAFDADNTQTLCEKLPFCDFGAVIDPPSADVTAHIVEMLAARG
                     EGDTEPALRGVRWLLAHQEKDGSWFGRWGANHVYGTGAVVPALVAAGIPFEHKAVRAAV
                     AWLCAHQNPDGGWGEDLRSYVDPSWIGKGVSTASQTAWALLGLLAAGERGPGVERGVDF
                     LVRTQLPEGGWDEPHFTGTGFPGDFYINYHLYRLVFPLTALGRYVEVTKHEHAG"
     gene            15989..17500
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /locus_tag="BAY61_RS14140"
                     /old_locus_tag="BAY61_14065"
     CDS             15989..17500
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /GO_process="GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009154303.1"
                     /locus_tag="BAY61_RS14140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14065"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_091798103.1"
                     /transl_table=11
                     /translation="MNTQAEDLVVVSPLMLEVSSVRRGLGGGCVVRAGPHARRSRRVET
                     ALRQHPGAAVAVAGVAGALVHDLRPGDLVVASEVRSAQGTHHCRSAPLLAAALRKAGLT
                     VHMGPMVESDHVVWQPEGARLALDGAIAVDMESARLLDLIGSRPSVVVRAVVDTPSRSL
                     LHPATVPGGIAALSALREVGPSLRKWAAATRDRTVLLAGPRSFCAGVERAVEIVERLLD
                     RHAPPVYVRKQIVHNSRVVGDLERRGAVFVEELDEVPENATVVFSAHGVSPAVREDASR
                     RRLDVVDATCPLVSKVHGEAKRFARDGDTVFLIGHAGHEEVEGTLGEAPDRTVLVERPE
                     DVADIEVEDPARVSYLMQTTLAMDEAEGVVTALRQRFPALRGPGSDDICYATTNRQDAV
                     RVVARDSDVVLVAGSPNSSNSLRLVEVAQREGTPAYLVDDVGELDLDWLASAGTVGLSA
                     GASAPTVLVDEIVDALAGLGAVQVRERTTATETVNFSLPKEVRHR"
     misc_feature    16280..16282
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17497..18504
                     /gene="hpnH"
                     /locus_tag="BAY61_RS14145"
                     /old_locus_tag="BAY61_14070"
     CDS             17497..18504
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019818822.1"
                     /locus_tag="BAY61_RS14145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14070"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_091798106.1"
                     /sec_met_domain="PF04055 (E-value: 3.4e-15, bitscore: 55.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.3e-08, bitscore: 33.1,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMPLHQAVRVARHIVTQKIRRNDKYPLIMELEPILACNLKCGGC
                     GKIQHPANILKQRMPVEQAVAAVEESGAPMVSIAGGEPLMHPQIDTMVNELTKRKKYVF
                     LCTNAVLLRKKIDNLDLKPSKYFAFAVHIDGLRERHDLAVAKEGVFDEAVAAVKELQRR
                     GFRVTTNTTVFNTDTPQSVIEVLDYLNDDLKVDEMMVSPAYAYEKAPDQEHFLGVQETR
                     ELFRKAFAGGNRKRWRLNHSPLFLDFLEGKVDFACTAWGVPLYTLFGWQRPCYLMSDGY
                     AETYRELIETTEWEKYGRGRDPRCANCMAHCGYEPTSVLATMGSLKETLRAARR"
     gene            complement(18835..19575)
                     /locus_tag="BAY61_RS14155"
                     /old_locus_tag="BAY61_14080"
     CDS             complement(18835..19575)
                     /NRPS_PKS="Domain: PKS_KR (8-166). E-value: 9.8e-07. Score:
                     20.8. Matches aSDomain:
                     nrpspksdomains_BAY61_RS14155_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005452329.1"
                     /locus_tag="BAY61_RS14155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14080"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_091798112.1"
                     /transl_table=11
                     /translation="MIDRGTRCVVTGGSSGIGAETAAALGSRGCEVLITGRDRKALADV
                     ARGTGARMCVADLTEPDGIATVLAEAGEVDVLVCNAGVGWAGSFADMPAAAIDRLVATN
                     LLAPARLIRGVLPGMLARGSGALGLVSSIAGSMSVADEAVYSATKAGVAALGASVRGEV
                     TGKGVTVSVVVPGVVSTPFFDRRGTPYRRSRPRPVPASTVAEALVAALEHGRPEVFVPR
                     WLRFPARLRGVAPGLTDSLQRRFG"
     aSDomain        complement(19078..19551)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BAY61_RS14155_PKS_KR.1"
                     /evalue="9.80E-07"
                     /label="BAY61_RS14155_PKS_KR.1"
                     /locus_tag="BAY61_RS14155"
                     /protein_end="166"
                     /protein_start="8"
                     /score="20.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVTGGSSGIGAETAAALGSRGCEVLITGRDRKALADVARGTGARM
                     CVADLTEPDGIATVLAEAGEVDVLVCNAGVGWAGSFADMPAAAIDRLVATNLLAPARLI
                     RGVLPGMLARGSGALGLVSSIAGSMSVADEAVYSATKAGVAALGASVRGEVTGK"
     CDS_motif       complement(19477..19551)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BAY61_RS14155_0001"
                     /evalue="5.60E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="BAY61_RS14155"
                     /protein_end="33"
                     /protein_start="8"
                     /score="15.8"
                     /tool="antismash"
                     /translation="VVTGGSSGIGAETAAALGSRGCEVL"
     gene            complement(19572..20492)
                     /locus_tag="BAY61_RS14160"
                     /old_locus_tag="BAY61_14085"
     CDS             complement(19572..20492)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009154306.1"
                     /locus_tag="BAY61_RS14160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14085"
                     /product="DMT family transporter"
                     /protein_id="WP_091798116.1"
                     /transl_table=11
                     /translation="MSGPSTVLWIAVPSAVLAAAAFGLTGALQHKAARRVVGGGTVQIG
                     LVFTLLRQPLWLASLLTNGLGIALQWLALATGPLVLVQPLLVTALVFAVFSSSALRGER
                     PDRIVLLGAGLCVAGLAVFFLVARPVAGHGRLELREVLPLAAGLAFLIVVCVAVAVEYA
                     GRVRVLALATATGVLYGVTAGLSKLAADDLRHGVSALLTHWHFYVVVVCGVTGFVLSQN
                     AFRVGVALAPALAVIVALDPLVSIGVGALWLGEQLPGGAGRIAGQVIGLAVSIAGIAVL
                     SRHAPQTAQAETYMARPEQTEKENR"
     gene            complement(20489..22942)
                     /locus_tag="BAY61_RS14165"
                     /old_locus_tag="BAY61_14090"
     CDS             complement(20489..22942)
                     /GO_function="GO:0004144 - diacylglycerol O-acyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_tran_28_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF018657.4"
                     /locus_tag="BAY61_RS14165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14090"
                     /product="WS/DGAT domain-containing protein"
                     /protein_id="WP_143021327.1"
                     /sec_met_domain="Glyco_tran_28_C (E-value: 1.7e-07,
                     bitscore: 29.8, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSELPRWRRTWQAWGKTGVIADQRVVMTTTGSGEPRRPERLLIVS
                     ADMGEGHNATGRALREAAERLWPGIEVHWVDVLETMGTATGPAFRRIYKTCVEKLPWLY
                     DFFYSSMWHHRWFATAAKRVIGAWSGRGLAPSIDRVRPDLVLSTYPMGSTGLQWLRRQR
                     GLSVPTAAWISDFAPHPSWVHDGVDLNLVMHEVAVAPARDSVPGAEVRVSAPPVAGAFR
                     PADRAAARASAGLGGARRVAVVSCGSLGFGRGDDTVRELLAGDPGLTVVVVTGRNERLK
                     TVLTNAFAGDARVRVLGWVDDMSRLMAAADVIVTNAGGATALEALACGRAVLLHNPIAG
                     HGRTNANLMAEAGLAIICTRAGELADALRPERAGELTALEAAAGGHAGRLRLSEGLMML
                     AEVPAKAHDRRLPAADALFLHAGTPKAPQYVGTVLVFSRGPRLTTRHVTGMISAVPGVG
                     GTLTGTGLLRGARWSGRRLTDPATLVDEISTGDLTQAADEFFSSPLRGGKLGAARLVTG
                     LPGGRRAVLVALHHALGDGMTVLQALLSDTDTSAGLTWATRPVTAVGGSGFRPEPRKLA
                     GGLWRLATAGGAPESPLDGALADAERRHALLRLPGRQVRAKARALEVSAAELLTAVFAE
                     SLHEVFGLPEHARFRLMVPWSLRGTGSLRTAGNHTGAVSIDLPVGPMELPERAALVAAT
                     MRERIEAGVPEAAHGVVRLLGALPPPLRPMAARGVYRGTWFNAIGTVMPGPRRKVTWHG
                     AVLTEAYPVLAVAPGTGLAWGAMTWGDGITLCFTAPAGLGPLAERIAKHTDAVFTEPAG
                     DTGRP"
     gene            complement(23064..24287)
                     /locus_tag="BAY61_RS14170"
                     /old_locus_tag="BAY61_14095"
     CDS             complement(23064..24287)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005465116.1"
                     /locus_tag="BAY61_RS14170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14095"
                     /product="PucR family transcriptional regulator"
                     /protein_id="WP_091798122.1"
                     /transl_table=11
                     /translation="MTSSAGRSGALDCSEPARDALHKLSRVLLDNLESLADRLTIMVLQ
                     REPAYAQLGVTAPDELRENLRCNIERGIQSLGGNVPDGEDPQDTSMETGRLRARQGVPL
                     EAVLRAYRLGGRVIWEGLLATSRERFAGYYDHALLDAAGYVWRVIDSSSSALVDAYRLE
                     ESRLRSQELSRRHAFLNALLEGRGRDTALAEEAASALGLPATGPLLCVVAPIDVPGEDP
                     LRSPRDVLAAHGILSSWHVRPSDIVGLVVLGERAPSAVLDVLGASAHGRVGCSPVVHRL
                     ADIADAYTLAQIAARTLPANGVAYLDDRLPEALLVGSPQLAPRLQRVAFGDLLALPEPE
                     RETMFKTLEATIECGGSPTHAAQRLYCHRNTVIYRLQRIESATGRKVSRPRDRLLFTLA
                     LLARKQSG"
     gene            24695..25468
                     /locus_tag="BAY61_RS14175"
                     /old_locus_tag="BAY61_14100"
     CDS             24695..25468
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019815574.1"
                     /locus_tag="BAY61_RS14175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_14100"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_245866215.1"
                     /transl_table=11
                     /translation="MFTATGVTVRFGGLTALDTVSLAARPHEVHGVIGPNGAGKTTLFN
                     VCCGFVEPDEGVLRWRGDPVGGLRPHQLAGMGIARTLQGLGLFAGLTVLENVMVGADRF
                     RRTGFGSALLALPRSAGDERRLRERAMAAMAELGLADAASAMPASLPYPVRKRVAFARA
                     LAADPELLLLDEPASGLGAADIAELGELVRGLASRMSVVLVDHHMDLVMAVCDHITVLD
                     FGRIVARGTPAEVKDDPAVIDAYLGEEADRSGDHG"
     misc_feature    25624..25639
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.08"
                     /tool="antismash"
ORIGIN
        1 gcggtgacga cgcgccggaa ctgcgcggca agtacctgtt cgcggatctc gtcgacggca
       61 gggtgttcta caccgagtcc ggcgagatgc gcaggggagc cgagccggcg accatccaca
      121 cgatgaggct gtacgacgag aacggaaact gggtcacgac accggaactg gccggtgaca
      181 ccagggtcga cctcagattc ggcagggacg ccgacggtga gctttatctg ctttccaagg
      241 cgaacggcaa gatctggaag atcaccggaa ccaagcgctt cgccgattgc cccaccggat
      301 cgaccgtggt caagaacgcc atgggcgaga agaactgggc tccggtgacg ccggagaaat
      361 gggaattccc ccgccgtgag gtggtgcttg ccgaggaggg ttcggagcgg cctggcccgc
      421 gaaggcccta cgagtacgcg gtgctcacca aggggcccga gttcggctcg gtgcgcctcg
      481 atgcgcaggt gcggctcgat acaccggtcg aggtgaccaa cagggacgtg gtgctcgtgt
      541 tcggctatca gtccgacacg cggttctact acgcgcatct gtcgacggac aacacgattt
      601 acccgcacaa cgggatattc gtcgtcgacg acgcggacag ggaacgcatc gaccatcaat
      661 gggatcccgt gcgctctcag ggagcggcgc ccgcgatcac cgacgccgag tggcacgagg
      721 tcagcctgac ccactgtgcc gaaacgggag agatcgccgt gtacgtcgac ggtcagcggg
      781 acccgctgat gacggccgtc gatccgacct tcacgtcggg aagggtcggg ttcggctcct
      841 tcgacaacgt cggcaggctg cgtgaccttt cggtcatggg gcgaaagagc tgacagcgga
      901 acggatccgt caccggccgc acaccacgtt ggcccagtcc tgggccgaca cgccggtgcg
      961 gatccgttcc agttcggcca gcagctggtc gagtcgcccc ggatcggcga ggtagccgag
     1021 ggcggcgcgg tggaaggcat tcgtcacggc cgtcggcatg aggtcggacg cgtcgtagca
     1081 caggactttc gccgtgctga tgatccgcgc gacgttcctg gtcaccgcgt ccgacccggt
     1141 ggtggcggcg acatcctggc gcaccgtgaa cacggcgccc cggtcggcct cgggccagat
     1201 gcgctgtcct tcggccgagg cgagaaaccg catgagttcc ctcgcggccg gggtgtcgcg
     1261 gaacatcgtc gcgaggtcgg cggaaacgag ccaggcgtcg ccgggcccgg aggggccggg
     1321 ggtggggaag aagtcgaacc gggcgccctt ggagcggtag tcgttgacga cgtaggaacc
     1381 ctgatgttcg aggaaacacc ccggatcggc ggcgaacatc gtgtcgttgg cggtggtgta
     1441 gttggtgagc agcgaaccac cgcgtccacc gtggacggct ccatcaccga gaatcagttc
     1501 gccccaggcg atccaggact cccgcacctc gggagccgtc cacggcaggt cgccggtgac
     1561 ccagcgctgg tacgtttccg gtccgtacct gcgaagcagg atgtcctcga tccagtcgga
     1621 gccgggaaaa ccggtcgccg acatggctcc catgcccatg caccacggtg ttctgccctc
     1681 ggccgccgcg gcgtcggtga gcgagacgag ctggttccac gtgcggggaa cggggccggt
     1741 gagcacgttg gggttgaacc agacgaggcc cttgagcgcg gccttgacca cgacggcgta
     1801 gggccgctcc gttccagcct gcgccagttg cagccattgt ggactgtagg ccgagcgcag
     1861 ttcgtcctcc agttccggca gttgacgcaa cgctccctgc cgctggtagt tcacgagttc
     1921 gttggggctc gacagtatgg cgatgtccgg cggggttccc tgctggacgt cggcggcgag
     1981 taccggactc agcgagcgcg tgccgaggta gtcgtagccg atgccggtct cgcgctcgaa
     2041 ttcgtcgagc acggcgcgga acgcggcctc ctcggttccc gtccacggcc cgatgatggt
     2101 gacccgctcc gcggtggtac acgcgctgac ctgggtgagc agagccagca ggaccagcaa
     2161 caccgctgtg cgcgcggttt tcatgaagga tgcccctggt attcggtgat ccggcgctga
     2221 aagccggtga tgatcagcac ggcgatgcca ccggcccccg cgacgatgag ccacagcacc
     2281 gcctgcggca atgccgcgcg gtcgaacccg gctgtcacgt cggcgccggt tccggcaagc
     2341 tgatcgtcgg cggttcccct cggcacggcg gacccggtcg gtgaggcggc gaactcggcg
     2401 accgagtcgc cgcagccgtc cggctggcag tgaccggtca ccagcacggc gaccgcgcgg
     2461 cggtcggcgg ccgccgccgt gtgcgcgcgt tgttgccaga tggtgatttc ctcgcgcaac
     2521 tcgttcgcgc cgtggtgtgc tcgcgcctgt gccgggatcg tcagcgcggg cagcgcggcc
     2581 accgcgatca gcaacccggt cgcggcgagc agatgcggat tgagtcttcg ccggaatcgc
     2641 cggtggtgat agacctgcgc cgcgcagagc aacacggcga gcgcggcgac cggaatcagc
     2701 cagatcgcgc tcgcgcccgg atgcatccaa tcgcgggcga gctggtcgtc cagttcgtcg
     2761 agctgggcgg cacgtaactg ggagagatgc ggcaggatcc cgtccgcgtc gtgcaagagt
     2821 tgcgccgcgt accagacgtc ggtggcaccg gccatcgagt cgtcgccggt gcgaaacctc
     2881 agttcggcct gcgacatcca gctcgtgtac gacacgagca gcccctgcac gagttgcagt
     2941 tctctgcggc tggccgaccc cgcgacgttg tgctcggcga cctgcgccag gttctggctc
     3001 gcgacgccga tctgtgcctg gtagaagtct cccgcgccgc tgagctggcc tggtcccagc
     3061 gcgaacgcgg tgacggctga ggtgttggcg tgcacgagtg cctcgtacac cgatgccgaa
     3121 ctgatgatcg cgggtgtcgt ccttccacgc atcgtgtcga tcgctgagcg cacaccggcg
     3181 aaggcagcga ccgaacccgc gagcacggcc accgtcaata ccaatgacca accgcgcagc
     3241 agccgcaacg tgcgcgccgt cgtgcttttg ccgtctcccg gccgcaccgt cgcgatggcc
     3301 gcggcaccaa gttgcgctgg aatccccatc agaaccaggt tttcggccgt acggtgttgg
     3361 cgagatcgat cagcacgccc tggctctcgg cgtccctcgc ctgcctggcc aatccgcgca
     3421 ggcactgttc gagctgagcc cctacggcgt tgcgccgttc cccgtcgccg ctcttaacgg
     3481 cgcggtgcaa cgcggcctcg tagacctcgg tgtcgaggcg gtcgcgcgcg gggcccgcgc
     3541 cgccgttttc ctcgtcgccc tccagattga gttctggacg gcgcaggaag gcgttgacca
     3601 gatcggtcga ggtgggcggg ccctcgccga ggtcaccgac gaacacgcgc accgtcgcga
     3661 tccgtgccgc gtagtagtgc agcgacaccg cgggaacctg gtcgagcacg gccaccgcgc
     3721 ccgctctgtc gtactcggca aggcgcagcc tcgccagcga gaacgcggcg ctgacctgag
     3781 tgcggtctcg ttgccacacc gcgtggtagt agtcggtggc gacgtcgggt ttgccctggt
     3841 gctccgcgca gtagccgagc gcgagcttgg gcgcggcctc accggcaagc gcgcggtgga
     3901 ccgagaagaa ctcggcctcg gcttcgagga tgtcggaccg ggtgagcgcg agcagtccgc
     3961 gatgccagcc gaggcgccag tcgtactcgc cgtcctcacc gagcgtcgtc gtggcgtagt
     4021 cgagccacga ccgtgcccgc tccggcgctc cgacttcgag gtgcgctctg cactgcgcga
     4081 gcgacaactc gacggtgtgg ccgttgttct cgacccatcc cgcgagctgg ccgagcctcc
     4141 tgcgggcgtc gggcgcgcgc atctcggtga ggaatccggc gcccgcgtcg gcagggtccg
     4201 gtagcggagg tggcagcatc agcgcgatgt cggcggggga ggggcggccg tcgtccagcg
     4261 gcggcgggga atagtcctcg gcgggagcgg ccgtccagcg ttcgagtggc ggcgctgccc
     4321 ccagcccgac gtcgaagagc gcgggggttt cggcgaacag cgccgaaggg acgggccttg
     4381 gctcgccgtc gcgcagcgac tggatctcgc gcaggacgcc gtcgagcgcg cccgccatgt
     4441 cggccgccga gacgaagcgc tgggcgaacg gggccgtcgc cctgtcgatc acgtgccgca
     4501 gcgacctgac cccgaacgcg gtctcacccg cgggatcgtc gtcactgacg gcgagcagtt
     4561 cgccgagcgt cacgccgagg gtgtgcaggt cggagcgcac ggtcacgccg tgttgcgcga
     4621 gttccgaatc gccgacctgg taacgccttg tcatcgcgag cggagtggtg tcgtcgccga
     4681 ccttcctggt cgcgccgaga tcgatgagct tgatccggtg accgccgtgc atgatgttgt
     4741 ccggtttcag gtcgcagtac agcagtccct ggccgtggag gtagtgcagg gcgtcgagga
     4801 gttcctgcgc gtagccgatg acgtgttcgg ccagcaacgg ttccccgaac acgtcctcgc
     4861 ccgcgccgag gcggccgagc aattccctga gcgagtggcc gttgacgaac tccatgacga
     4921 tgtagccgtc cggttcccgc tcggccgacg cgcggtgcag tacgaacccg aagatgcgca
     4981 cgatgttggg gtgattgagc gcggtcagcg tcttgcgctc ggcctcggcg agcttcgtgt
     5041 ccgacgggtc gatcatgcct ttcagcgcga cgtacagctc gtcgagctcg atgtccttgg
     5101 ctaggtagac ccagccgagg ccgccgtggg cgaggccacc gatgacctcg tacttgcccg
     5161 cgagcacggt gccgggggca agcgcgggtt cggggtcggc gggtgcccct tcgacgagcc
     5221 cgctcggcga aggcacctcg acgaagggca gctgcgcccc tgccgtgtcg tagcgcggta
     5281 gccggggaaa cccgagcagg tcgccgccga gctcctccgt ggtggcctcg cgcgaggcga
     5341 accggtcggg agcgagcgtc gtcgtgttcg gccttgtcgg gtggcgaggc acgagaagca
     5401 accttaccga acgaaaacgc ccggttacgc cggttccggg tttccgtgct cgatcaccgg
     5461 ggcgcgaggt gcccgtaatg cccgtcgtag cgccggtaga cgacggcgcc ccggctggtg
     5521 gtgctgtcga ggaagaaggt gaacggcagc gccgtctcgt cgagtctgcc ggcggcctcg
     5581 gccggagtct ggtgcgggac gggatggacg ttgacggtga gcggtacggc ggccggtccc
     5641 gccggaggcg ccagcgacgc caggcgggcc agcttgtatc cggtcggccc cacccggtag
     5701 acgacgctgt cttctcccgt ctcgctgtcg gtgaagaggt agaagtcgta gtccatcagg
     5761 tccatcgtga acgtggcctc gcccggcgcg cactcggtca gctcgtaggt cttgtgccgc
     5821 acgatctccc tgcgcccggt gaccttcgcc gtggcaggcc ccagcggggc ggctccgtcc
     5881 cacggcctgc cggtgcgcgg cgcggtcagc atcgcgatct gttctttcag cctggcccgc
     5941 agcaggccgg ccgcctcggt gaagaacggc gccgccacct gtgcccgtac ggggcgtcct
     6001 tcgatctgga ggttcgcctg tgccagcgcg ggaacgggcg cgctcggttt ggtgaaggcg
     6061 gtgagtttga cgcgcgcggc gtcgagccgg gccggtagcc gcctcgcgaa cgtcgtgagc
     6121 tgtttccgca cgtactcctt ggctccgtcg agcacctccc cgcgcgtgtg caccacgatt
     6181 ccgttcgcca cgctcgcgtc gccctgcctg ctcaccgcgt caccaccgcc tttttctgat
     6241 gttccgccgt gatcatgatg gccggtgaag gtgacgaaca gggcacaagg tccctcgacc
     6301 gtgccggtca caggtcgggc gcggggctcg gcacactgcg cggccgaccg agcagcggga
     6361 gcacgtcctc gtcgctgacc ggggagaagt cccggtacca atggccgacc gcgcgcatcc
     6421 acaccctcgg gttgggacac acggtgtgat cggcgttgtg ggccagctcc tcaagtacgt
     6481 cggcaggggc gacgggcacg gcgagcacga ctctgccggc ctgcctgccg cgaaggacgc
     6541 gcagtgccgc tctcaccgtc gcgccggtgg cgatcgcgtc gtcgacgagc acaaccgtcc
     6601 tgcccgctac ggacagtggc gggaggtcgc cacggtaaag ctcagtcctc cggtcgagtt
     6661 cggcgagcgc ggtgcgcacg gcgaggtcca tgtcctgcct gctgaggcgg tattccctga
     6721 gcaggtcggc gttggtgacg agtacgccgc cctcaccgac ggcgccgacg gccagttccg
     6781 gcctttccgg cgcgcggacc cgctggacga gcaggacgtc cagcgcgcag ccgagtccgt
     6841 cggcgacctg cctggcgacg acggcgcccc ctcggggcag gccgagcacg atcgggtggt
     6901 gcgcggacag gtagccgagc ctgccggcca gttccctgcc cgcgtcggca cggttctcga
     6961 attgcatggt gcccgcctgt catcgcgcgc gtgtccctcg tgccgatcct cgggtagtca
     7021 ccggccgggg tgaagggtcg aaggtcccgc gtcctgcctt tgcgtggcgg tgcgggcgcc
     7081 tgtccttcaa ggtggatgga aagggccgga tccggaaacg gtgcgggcgg ccccggcgcc
     7141 gggtgaggcc gagcccgcga agcaggtgga gcattcgagc ggggagtgga aaacatgggt
     7201 gctgaggacg cggcgagcgg agcggtcgtc gtcggagtcg acggttccga atcgtcggga
     7261 tgggcggtgg actgggccgc ggcactcgcg gcgcaacgcg accttccggt gcggatcgtg
     7321 catgcctacg ggctcatcgg caggtactac ggtgccgagc tcgccgtccc gatgaacgtt
     7381 ctcgaagccg tcgacgagga cgcgcgcggg ctcgtggcgg cggccgccga gcaggcgcgc
     7441 gggctggcac ccggggtgga ggtgacctcc gaggtgttcg acgagccgcc gattccgttg
     7501 ctcaacaagc tctccgccga ggcgaagatg gtggtgctcg gccaatccgg tctcggtggc
     7561 ttcgcgggga tgctcgccgg ttcgacggcg ctgggcgtcg ccagtcacgc gagcgccccg
     7621 gtcgcgatag tacggaggag agaaggcggc gagcggccag ccgagggacc tgtcgtcgtg
     7681 ggcgtcgacg gcagccaggt cagcgagcag gcggtcgccg tcgcattcga ggaggcgtcg
     7741 ttccggggcg tgccgctcgt cgcggtgcac gcgtggatgg acgtcgagta tccgatcggt
     7801 ttcaacaagg cgagggagta tttcgagacc ggaccggtgg agcaggagga aaaccgggtg
     7861 ctcgccgaac ggctcgccgg ctggcaggag aagtaccccg acgtgcctgt cgaacgggtc
     7921 gtggtgaggg acaagccgcg caaccagctc ctcgaccggt cccgcgaggc ccagctcgtc
     7981 gtggtcggca gcaggggaag gggcggcttc accggcatgc tgctcggctc cacgagccag
     8041 gcgttgttgc atcacgcgga gtgtcctgtc gtcgtcgcga ggccggtgaa aggcgaacgg
     8101 gccgggtagg cagggcctga acgatccgtg cgggaacgac caggaggagg ccggtccgat
     8161 gtggcagtcg gcgacgttgc tggccaggtt gtggcggcgc attcaccccg gccgcaaccc
     8221 gttggtcagg ctgtccgaca gggtggagag cgccgcgctc gtcgccgcgg tcgtgattcc
     8281 cctgctggca ctgccgttcg tcgcggcggt gggatcggac agttacgccc gcgagatcgc
     8341 ggtggcacaa cagcaacaac gcacgcgcca cgaggtggag gcggtgctgc tcaccgacgc
     8401 gccggccacg cagcggaaca cgggaacggc gggaacgggg ccgacggtgt cggcgcgagc
     8461 ggaatggtcg ctgccggacg ggagcaggcg caccggaatg gttcccgcga gggcagccgc
     8521 accggccggt acgacggtcg agatctggct tgacgagacg ggcaggccgg ttcctccgcc
     8581 gatgtcgcga ggggtgatcg cctggaacgc cttcgcggtg tcactgacgg tgtggatcgg
     8641 tgtcgtgctg ctgtccgggt tgttgttcgt ggcactgcgg cacgcgctcg atcgcggcag
     8701 gtatcaccgg tggcaaagcg aatggtcggc tttcgacagg gagcgccacg aatcctgacc
     8761 ccagcgccga gttccgcatc gcccacatgc gaccgtccgg ctgagcaatg tggacagctg
     8821 gtgcgcgcct caggggacgc gttcgacggg ggcggcgagc cgcgccccgc ccagttcggt
     8881 ctcgatgtcg gcggcgacgg cggccagtag ttcctccgtg aggtcgttga gggcgcgggc
     8941 cagcgccagt tcccccgcga tctggggaac ccttgccacg tcgagtcctc ggtaggccag
     9001 tccgatgccg tcgaagtggt tgccgaggtc gtcaccgagc cggactcgtg ccctggtggt
     9061 gccgtcgttc tcgtcgagga cgatggacat cgtccattga gcggggtatg tcattgtctc
     9121 gcctccgaat tgcgcatcca ccgtcgcagc gggggagtgt gcgtttctag ggccgtttgt
     9181 cactttcccc gacgtggggg ccggtgaggg gggccggtac gcgggggcgg tgagaaactc
     9241 acctgacccg gcgggaggcg gccagtgcga aacaatgcgg aaccgggtgc tcgcggcgcg
     9301 gaaatggcga agtggacagc ggtaccgaaa taactgtaca cagtggactt aacgaactca
     9361 tcgagaggat tcggagacgt gcgtgtcacg caccgaaacc gtgatcatta tacgcttctt
     9421 cgcggaagat cgcctgtgtc acgcgcgttg tcacacgttg agacgatttc gcggaccggt
     9481 attcgtgtta acacatttca ccaagaagaa cccgccggtg cgcgactcga atgcgcgcgg
     9541 gccggaggtc agtgacaaaa ctgttgcgcg tgcccggtga ggaaataaga tcgttcccgg
     9601 tgaacgcggt agccggaatg gcgggccttc tcggccccgg tcgtggcgtg cgccgggcag
     9661 gtggtgcgaa gggccgcccg gtgatctcgc ggaccggaaa cgcggtgcga ggccgggcac
     9721 cccgccgccg ggagttgccc gaggtcgcga cgctggctga caatggaggt ttcgatgctc
     9781 cgacgattgg tgccgtggcc gaacgggacg aggcggatcg catgcagtcc atgcagtcgc
     9841 tcggcgagtt gtcaccgctg gagggagcgc gcacggccgg gcggccgccc gagcgcgccg
     9901 caccacttga ccacaccgcg aacccacagg gcgtactcgc cctcaccgga ttccctgctt
     9961 cgtgttggag gcgtgattga gacccgcgga ccaatccacc ttgggagacc gggcggtctc
    10021 ggccgccggt gctccggcag ccgagacctt cgagagcgcg gattccgtgc ccgcgctgca
    10081 cggggtgctc gccaaagccc gtagtgagaa ctttcccgtc gcctcctggc tgctgccccc
    10141 ggcccatcgc gggcacctgc tcgcgctgta cgccttcgcc cggatggtcg acgacatcgg
    10201 cgacgaggcc gccggcgacc gcttgcgatt gctcgacgcc gtctccggcg acatcgcgag
    10261 gttgttcgcg ggtgcggctc ccacgaccaa gctctacgcc gacctggcgg ccaccgtcca
    10321 cgaacggggg ttgccgaagg aaccgttcga ccggctcatc gaggccaacc ggcaggacca
    10381 gtcggtgtgc cgctaccgca ccttcgacga cctgctcggc tactgcgcgt tgtcggctga
    10441 tccggtcggc agactcgtac tcggggtctt cggcgcggac acaccggacc ggcgggtgct
    10501 gtccgaccgg atctgctcgg cgctacaggt gctcgaacac tgccaggacg tcgcggaaga
    10561 cgtgaggcaa ggccgcatct atctcccgct ggccgacctc gatctgttcg gggtcaccga
    10621 aagtgacctg ttcgccgagc gggcgggaag gccactgcgg gcactgatcg gctacgaggt
    10681 ccagcgagcg gtcgcgatgc tcgacgaagg agcgccactg gtggccacgc tgcgcggcac
    10741 ggcgcgggtc gccgtcgccg gttacgtcgc gggaggcagg gcgaccgcgg tggccatcgc
    10801 ctcggcccgg ttcgacgtgc tcgccgggac gccgaaaccg gcgaagaccc gtacggccgc
    10861 cgaatggctg cgcctgctcg gcaagggcgg tgaccggtga ataccgccga agcctacgcc
    10921 gaatgcgaac gcatcacccg cggacaagcg cgcaacttct cctacggcat ccggctgctg
    10981 cccgctccga agcgcaaagc actgtcggcc gtgtacgcgt tcgcgaggcg aatcgacgac
    11041 atcggcgacg gcgacctccc cagtgaacag aagctggagg cgctggagaa cgcgaggaaa
    11101 caactccacg atctcggcgg ctccggcgac gatccggtac tcaccgggct ttggcacgcg
    11161 gcgtggcgat tcgagttgcc gctcggcgcg ttcgacgaac tcatcgaggg ctgcaccgcc
    11221 gacgtagtag gcaccagcta cgagacgttc gacgaactgc gccactactg ccggtgcgtc
    11281 gcggggtcca tcggcaggct ttcgctggcc gtcttcggct cgcccgatcg cgcgcgcgac
    11341 gagcggatcg ccgacgatct cgggatcgcg ttgcagctga ccaacatcct gcgcgacgta
    11401 cttgaggaca gggtcgccgg gcggatttac cttccggcag aggacctgcg tgccttcggc
    11461 tgcacgctgg acctgacgga gcgggccgag cttgccgacc ccgaggacgc gctgctgccg
    11521 ttgctggagt accaggcggc ccgggccgag gaatggtacg aatgcgggct gcggttgctc
    11581 ccgctgctcg attcccgcag cagggcctgt tgcgcggcca tggccggtat ctatcaccgc
    11641 ttgctgcgca ggatggcgtt gcggccccgg ttcgtgttgc gcggccgaac atcgttgccg
    11701 gactgggaga aaatcgcggt cgcggggcgg gcgcttgcgg gaacgtcgcc atgagcgcac
    11761 acgtggcggt cgtcggcggt gggctcgcgg ggctcaccgc ggcctgtgat ctgtccgacc
    11821 gcggcgtgcg cgtcacgctg cttgaggcgc gcaaccggct cggcggagcc acgttctcgt
    11881 tccagcggga cgggctcacc gtcgacaacg gccagcacgt gctgttgcga tgctgcacgg
    11941 aataccgtgc cctgctggaa aaactgggta ccgccgacgg gatcgacctg cagcggcgat
    12001 tccgtatgcc ggtgctcacc ggtggtgggg ccggtgccga actcgcccgc accggcgggc
    12061 ccgcgccgtt gcatctggcc gccggtatcg cccgctacgc cgcgctgccg gtcaccgacc
    12121 ggatccgggt tttccgcgcc gccgcggcgt tgcggttcct cgacccagcc gaccccgcgc
    12181 tcgaccggct gagtttcgcc gactggctgg ggcggcacgg acagaacgac gcgacgctgc
    12241 gcggcctgtg gaacctcatc gcggtcgccg cgctcaactg tgacgcgagt gaggcttcgc
    12301 ttgcgctggc cgtgatggtt ttccggaccg cgttgctcga ccgcgcggat gccgccgaca
    12361 tcggcgtccc cgcgttgccg ctgagcgaac tgcatgtcga tccggccgag aagtatctgc
    12421 tcgaaagggg cggctacgtc cgcacccgca gccccgtgcg cgcgatccgg cggcagggcc
    12481 gagggttcac catccgactc gacgacgagg cgatcgacgt cgacggagtg gtcatggcgg
    12541 cgcctcccga cgcggccgcc ctggtctgtc cacgcgaggc cgggctcgat ccggaccggc
    12601 tcgggaagct gggcgccgcg cccatcgtca acgtgcacgt cgtctacgag cgaccggtca
    12661 ccgatctgcc cttcgccgcg acggtgtcac cgtcctcgcc ggtgcagtgg atcttcgacc
    12721 gcaccggggt cgcgggactg gacagtggcc agtacctgac cgtctcgctg tcggcggcac
    12781 accgctggct cgacaccccg gtcgccgaac tgcgcgagat cttccttccc gaactggcca
    12841 ggttgcttcc cgccgccgct ggcgtcccgc accggcagtt cttcgtgacg agggagcggc
    12901 gcgccacctt ccggcagggc cccggaacgg cagcgctgcg cccgcgcgcc gcgaccaggt
    12961 tgcccggact cgcgctggcc ggctcgtgga cggcgacagg gtggccggac acgatggaag
    13021 gagccgtgcg cagcggccat caagctgccg gtctcatcgt cgagcacatc gggggaggtt
    13081 cgccatgacc agcacgctgc cagccgaggt gacggcgacg agaacgctcg tgcagcccgc
    13141 gctgcgcgag gccgtgcgct ccttgcagcc ggccatgcgc cgggtcgtca gctaccacct
    13201 cggctggacc gacgagcacg gccagcccgc cgacgcgggc ggtggcaagg cattgcggcc
    13261 cgcgctcgcc ctgctcgcgg cgcaggccgt caaggcggct cccgaggcgg cgctgcccgg
    13321 cgccgtcgcc gtcgaactgg tgcacaattt ctcgctgctg cacgacgacg tcatggacgg
    13381 cgacgtcgaa cgcaggcacc ggccgacggt atggcggctt ttcgggactc ccgccgcgat
    13441 actggcgggc gacgcgttgc tgacgctcgc cgtcgacgtg ctggagcggg cggcggaccc
    13501 ggtcgccaca cggtgtctca ccgccgccgt gcagcacctc atcaccgggc agagcgccga
    13561 cgtcgacttc gagaaccggc tggacgtcgg tgtcggcgaa tgcctcgaca tggcggcggg
    13621 aaagaccggg gcgctcatgc ggtgcgccgc ccaggtcggt gcgctgctcg gcaggggaag
    13681 cccggtcgcg gcgggcctgc tggccgagtt cggcagcaac ctcggcatgg ccttccagct
    13741 cgtcgacgac ctgctgggta tctggggcag tcccgaggac accggcaaac cggtgctcgc
    13801 cgatctgcgc gtgcgcaaga aatccgtgcc cgtcgtggcc gcgctcaact cgggaaccga
    13861 gtacggggcg gccttgcgcg agctgtaccg gaatcccgat ccgcccacag aggaggaagt
    13921 gcacacgatg gcagagctga tcgagcgttc cggtgcgctg gcgtggacgc gagagcgagc
    13981 acaccggtat gtcggcgagg cgggcacctg cctcgaccgg ctggcccctc ccgaaccgat
    14041 ccacgcggcg ctgcgagacc tgaccctgtt cgtcgtggag cgtgaccgat gagccacgta
    14101 ctcgaccggc cgatggcgac ggtctcggcg agggcggccg aggcgaccga gcgggcccgc
    14161 caccacctgc tttccctgca acacgaagaa ggctggtgga agggcgagct ggaaaccaac
    14221 gtgacgatgg acgcggaaga cctgatgctg cgccagttcg tcggcatcgc cgacgaccgg
    14281 ttgctggccg agtcggcacg ctggatccgg tcctgccaaa gggaagacgg gacgtgggcc
    14341 aatttctacg gtggccccgc cgatctgtcc acgacggtcg aggcatacac ggcgctgcgc
    14401 atggcaggcg acccggccgg atccccgcat ctgcgcaggg ctcgtgagtt cattctggac
    14461 agtggcggaa tcgaggcgac cagggtcttc acccgcatct ggctcgcgtt gttcggggaa
    14521 tggtcgtggg accggcttcc cgtgctgccg cccgaactcg tgctgcttcc gcactggttt
    14581 ccgctcaacg tctacgactg ggcgtgctgg gcgcggcaaa ccgtcgtgcc gctcacgatc
    14641 gtcgcatcga gcaggccgcg caggccactc ggggtcagcg tgcaggagtt gcgaacagga
    14701 aagcccgtcc ccgagccgga ttcgccgctc acctgggccg gcgccttcca gcgactcgac
    14761 tcggttctgc acatcgcgga gaagtttccc gtcaagccgc tgcgccgaat cgcgctgtcc
    14821 accgcggaga agtggatcgt cgaccggcag gaggccgacg gcggctgggg cggcatccag
    14881 ccaccgtggg tgtactcgat tctggcgctg aacttgcgtg gctactcgac ccgccatccc
    14941 gtgctgcgca aggccatcga gggacttgag ggcttcacga tcagggaacg caccgaagag
    15001 ggctgggtac gcaggctgga ggcatgccag tcgcccgtgt gggacaccgc gctcgcgctg
    15061 accgcgctgc tcgactccgg actggcgccg gatgatcccg ccctggtgaa agcggcggac
    15121 tgggtgctga gggaggagat ccgctcggaa ggtgactggc aggtacggcg cggtgacctg
    15181 gcaccgtcgg gatgggcttt cgaattcgcc aacgaccact atcccgacac cgacgacacc
    15241 gctgaggtca tcctcgggat gcgccggatc gaccatcccg agccgcaccg gttgcgtgag
    15301 gtgctggaca gggccgcggc atggacggcc ggaatgcaat cgaaggacgg tgggtggggt
    15361 gccttcgacg ccgacaacac ccagaccctg tgcgagaaac tgcccttctg cgacttcggt
    15421 gccgtcatcg acccgccgtc ggccgacgtg accgcgcaca tcgtggagat gctcgccgcg
    15481 cgaggtgagg gcgacaccga accggcgctg cgcggcgtgc gctggttgct ggcacaccag
    15541 gagaaggacg gttcctggtt cggaaggtgg ggcgccaacc acgtctacgg gaccggcgcg
    15601 gtcgttcccg cgctcgtcgc ggccgggatt cccttcgagc acaaggcggt cagggccgcc
    15661 gtcgcctggc tgtgcgcgca ccagaatccc gacggcggct ggggtgagga cctcaggtcc
    15721 tatgtggatc caagctggat cggcaagggg gtttcgacgg cgtcgcagac ggcgtgggcg
    15781 ctgctgggcc tgctcgcggc cggtgaacgt ggtcccggcg tcgaacgcgg tgtcgatttc
    15841 ctcgtgcgca cccagcttcc cgaaggggga tgggacgaac cccacttcac cggaaccggt
    15901 ttccccggcg acttctacat caactaccac ctttaccggc tcgtcttccc gctgaccgcc
    15961 ctcgggcgct acgtggaggt gaccaagcat gaacacgcag gctgaggacc ttgtcgtcgt
    16021 ctcccctttg atgctggagg tcagcagtgt ccgcagggga ctcggtggcg gatgcgtggt
    16081 gcgagcgggt ccgcacgcgc gcagatcacg cagggtcgag accgcgctga ggcagcaccc
    16141 aggggcggcg gtcgccgtcg cgggcgtcgc cggtgcgctc gtgcacgacc tccggccggg
    16201 tgatctcgtc gtcgcgagcg aggtgcgctc cgcgcagggc acgcatcact gccgttcggc
    16261 accgctgctg gccgccgcgt tacggaaggc gggactgacc gtccatatgg gaccgatggt
    16321 cgaatcggat cacgtcgtgt ggcagccgga aggggcgcgc ctcgcactcg acggtgccat
    16381 cgccgtcgac atggaatcgg cgcggttgct ggatctgatc ggctcgcggc cctcggtcgt
    16441 cgtccgtgcc gtcgtcgaca cgccgagccg gtcgctgctg catcccgcga cggtacccgg
    16501 cggtatcgcg gcgctgtcgg cgctgcgcga agtgggcccc tcattgcgaa agtgggcggc
    16561 cgccacgcgt gatcgcacgg tgctgctcgc gggaccgagg tcgttctgcg ccggggtgga
    16621 acgcgccgtg gagatcgtgg aacggttgct cgaccggcac gcgcctccgg tatacgtgcg
    16681 caagcagatc gtgcacaact cgcgggtcgt cggcgacctg gaacggcgtg gtgccgtctt
    16741 cgtcgaggaa ctggacgagg tgccggagaa cgccaccgtc gtgttctcgg cgcacggcgt
    16801 ttcccccgcc gtgagggagg acgcgagcag gcgtcggctc gacgtcgtcg acgccacctg
    16861 cccgctggtg tccaaagtgc atggtgaggc caagcggttc gccagggacg gcgacacggt
    16921 gttcctgatc ggccacgccg gtcacgagga ggtggagggg accctcggtg aggcccctga
    16981 ccgcaccgtg ctcgtcgagc gacctgagga cgtcgcggac atcgaggtcg aggaccccgc
    17041 gagggtgtcc tatttgatgc agacgacctt ggccatggac gaggcggaag gcgtcgtgac
    17101 ggcgctgcgg cagcggtttc ccgcgttgcg tggccccggg tccgacgaca tctgctacgc
    17161 cacgaccaac cggcaggacg cggtacgggt cgtcgcccgt gactccgacg tcgtgctggt
    17221 cgccggttca cccaactcgt ccaactcgct gcggctggtc gaagtggctc agcgagaggg
    17281 aacgcccgcc tacctggtgg acgatgtcgg cgagctggat ctcgactggc tcgcctcggc
    17341 gggaacggtc gggctctccg ccggtgcgtc ggcgccgacc gtgctggtcg acgagatcgt
    17401 ggacgcgctg gccggattgg gcgcggtaca ggtgcgggaa cgcaccaccg ccaccgagac
    17461 cgtgaacttc agccttccca aggaggtgcg tcaccgatga acatgcccct gcaccaggcg
    17521 gtgcgcgtcg cgcggcacat cgtcacccag aagatccgga ggaacgacaa gtacccgctg
    17581 atcatggagc tggaaccgat tctggcatgc aacctcaaat gcgggggctg cggcaagatc
    17641 cagcatccgg cgaacatcct gaaacagcga atgcccgtcg agcaggccgt cgccgcggtc
    17701 gaggaatccg gtgcgccgat ggtgtcgatc gcgggcggcg agccgttgat gcatccgcag
    17761 atcgacacca tggtcaacga gctgaccaag cgcaagaagt acgtgttcct gtgcaccaac
    17821 gcggttctgc tgcggaagaa gatcgacaac ctggatctga aaccgtcgaa gtacttcgcg
    17881 ttcgcggtgc acatcgacgg gctgcgcgag cggcacgatc tcgccgtcgc caaggaaggt
    17941 gtgttcgacg aggccgtcgc ggcggtcaag gaactacagc ggcggggttt ccgggtcacc
    18001 acgaacacga ccgtgttcaa taccgacacc ccgcagagcg tcatcgaggt gctggactac
    18061 ctcaacgacg atctgaaggt cgacgaaatg atggtctccc cggcgtatgc ctacgagaag
    18121 gcgccggacc aggaacactt cctcggcgtg caggagaccc gcgagctgtt caggaaggcg
    18181 ttcgccggtg gcaaccgcaa gcggtggcgg ctcaaccatt cgccgctgtt cctggacttc
    18241 ctcgaaggca aggtcgactt cgcgtgcacg gcgtggggtg tgccgctgta cacgctgttc
    18301 ggctggcagc ggccgtgtta tctgatgagt gacgggtacg ccgagactta ccgggaactc
    18361 atcgagacga ccgagtggga gaagtacgga aggggccggg acccgaggtg cgccaactgt
    18421 atggcccact gcgggtacga accgacgtcg gtactggcga cgatgggttc gctcaaggag
    18481 accctgcgag ccgcccgccg ctgacccgcc gcccgccgac gagtccccgg ctggtgcccg
    18541 gcggctggtg cccgttcgcc ccgtcggcga gtcccccgtc caggacgtcg agttctgcgc
    18601 ccaggtcggc gagttccgcg ttccggttgc cgagttctgc atccgtgcga gcgagttctg
    18661 cgttcgcggg ctgttggcgt ggcgcccgcc ggccgcgccc gagcgcggat gtcgccgccc
    18721 cggacgcgga tgtcgccgtc ccgagcgcgg atctcgccat cccgggcgcg gatctcgccg
    18781 tcctgagtgc ggatgtcggc ggtctgggcg ggggactcgc gcagggctgc ggcgtcagcc
    18841 gaaacggcgc tgcaaggagt cggtcaggcc cggcgccaca ccgcgcaacc tggcgggaaa
    18901 ccgcagccat cgcggaacga acacctcggg cctgccgtgc tccagcgcgg cgaccagagc
    18961 ctcggccacc gtactcgccg gtacggggcg cggccgggac cgccgatacg gcgtccctcg
    19021 ccggtcgaag aacggcgtcg acaccacacc gggaaccacc accgacaccg tgacgccctt
    19081 tccggtcacc tcgccgcgca cgctcgcacc gagtgccgcc acacccgcct tcgtcgccga
    19141 gtacacggcc tcgtcggcga cgctcatact ccccgcgatc gacgacacca ggcccagcgc
    19201 gccgctgccg cgcgcgagca ttcccggtag cacaccccgg atcaagcgcg cgggagcgag
    19261 cagattggtc gccacgagcc ggtcgatggc ggcagcaggc atgtccgcga acgacccagc
    19321 ccagcccaca ccggcgttgc acaccagcac atcgacctca cccgcctcgg cgagtaccgt
    19381 ggcgatgccg tccggctcgg tcaggtcggc gacgcacatc cgggctccgg taccgcgggc
    19441 gacgtccgcc agcgccttcc ggtccctgcc cgtgatgagc acctcgcaac cacgggagcc
    19501 aagcgcggcg gccgtttccg cgccgatccc cgaggaacca cccgtgacca cacaccgcgt
    19561 acccctgtcg atcaccggtt ctccttctcc gtctgttccg gccgagccat ataggtctcg
    19621 gcctgcgcgg tctgtggcgc gtgcctgctg agcaccgcga ttccggcgat gctgacggcc
    19681 agcccgatca cctgtcccgc gatccggccc gctccgccgg gcaactgctc gccgagccac
    19741 aacgcgccga ctccgatgct gaccagcgga tccagcgcca cgataacggc aagcgccggc
    19801 gcgagcgcca caccgacgcg gaacgcgttc tggctgagta cgaacccggt gaccccgcag
    19861 acgacgacaa cgtagaaatg ccagtgcgtg agcagtgccg acaccccgtg ccgcaggtcg
    19921 tcggcggcca gtttggacag tcccgccgtc accccgtaca gcacgccggt cgccgtggcc
    19981 agcgccagca ccctgaccct gcccgcgtat tcgacggcga cggcaacgca caccacgatg
    20041 agaaaagcca gtccggcggc gagcggcagc acctcgcgaa gctccagcct gccgtgcccg
    20101 gcgaccggtc tcgccacgag gaagaacacc gcgagccccg cgacacacag ccctgccccg
    20161 agcaggacga tccggtcggg gcgttccccg cgcagcgcgc tgctggagaa cacggcgaac
    20221 accagcgcgg tgaccagcaa cggctggacc agcaccagcg gcccggtggc gagcgcgagc
    20281 cactgcaacg cgatgccgag cccgttggtc agcagcgacg cgagccacag cggctggcgc
    20341 agcagggtga acacgagtcc gatttgtacg gtgccaccgc cgacgaccct tctcgccgcc
    20401 ttgtgttgca gcgccccggt gagcccgaag gccgccgcgg ccagcacggc ggagggcacc
    20461 gcgatccaca ggacggtgct cgggccgctc atggcctgcc ggtgtcaccg gccggttcgg
    20521 tgaacacggc atcggtgtgc ttggcgatgc gctcggcgag ggggccgagc ccagcgggag
    20581 cggtgaaaca caacgtgatc ccatcacccc aggtcatggc gccccaggcg agtccggtcc
    20641 cgggtgccac ggcgagtacg ggatacgcct cggtgagcac ggcgccgtgc caggtcacct
    20701 tccggcgcgg gcccggcatg acggtgccga tcgcgttgaa ccacgtcccc cggtagacgc
    20761 cccgggccgc catcggccgc agcggcgggg gcagcgcgcc gagcagccgc accaccccgt
    20821 gcgctgcctc tggcaccccc gcctcgatcc tctctcgcat ggtcgcggcg accagggccg
    20881 cccgttcggg cagctccatg gggccgacgg gaaggtcgat cgacacggca ccggtgtggt
    20941 tgcccgcggt gcgcaggctg ccggtgccgc gcaacgacca cggcaccatg agccggaacc
    21001 gcgcgtgctc gggcagaccg aacacctcgt gcagcgactc cgcgaacacg gcggtgagca
    21061 actcggccgc gctcacctcc agcgcccgtg cctttgcccg cacctgcctt cctggcagcc
    21121 gcagcagggc atgccttcgc tccgcgtcgg cgagcgcacc gtccaacggc gactcggggg
    21181 cgccgccggc cgtcgcgagc cgccacaggc cgcccgccag cttgcggggt tcgggccgga
    21241 agccggagcc gccgaccgcc gtcaccggtc tggtcgccca cgtgaggccc gcgctcgtgt
    21301 ccgtgtcgga cagcaacgcc tgtagcaccg tcatgccgtc accgagggcg tgatgcagcg
    21361 cgacgagcac ggcgcgccgt ccaccgggaa ggccggtgac gaggcgggcc gccccgagct
    21421 tgccgccgcg cagcggggag gagaagaact cgtcggccgc ttgggtgagg tcgccggtgc
    21481 tgatctcgtc gacgagcgtg gccggatcgg tgagccggcg cccgctccat cgcgccccgc
    21541 gcagtagccc ggttccagtc agtgtgccgc cgactccggg taccgccgag atcatgcccg
    21601 tgacgtgccg cgtggtgagc ctcggccctc gcgagaacac caagacggtg ccgacgtact
    21661 gcggggcctt cggtgtcccc gcgtgcagga acagcgcgtc ggcggcgggg aggcggcggt
    21721 catgggcttt cgccgggacc tccgccagca tcatcaggcc ctcggaaagc cgcagtctgc
    21781 ccgcgtgccc gccggccgcc gcttccagcg cggtcagctc acccgcccgt tcgggacgca
    21841 gtgcgtcggc aagttcgccc gctcgggtgc agatgatcgc cagtccggcc tcggccatca
    21901 ggttcgcgtt cgtgcgcccg tgccccgcga tggggttgtg cagcagcacg gctctgccgc
    21961 aggcgagcgc ttcgagcgcg gtggcaccac cggcgttggt gacgatgaca tcggccgccg
    22021 ccatgagccg ggacatgtcg tcgacccagc cgagcaccct gaccctcgca tcgcccgcga
    22081 aggcgttggt cagtacggtt ttcagccgtt cgttgcgccc ggtgacgacg acgaccgtca
    22141 gaccgggatc ccctgccagc aactcacgta cggtgtcgtc gcccctgccg aatcccagcg
    22201 agccacagga aacgacggcc acccgccgcg ctccgcccag cccggcgctc gcgcgggcgg
    22261 cggcgcggtc ggccggccgg aaggcgccgg caacaggtgg tgcggaaacc ctgacctcgg
    22321 caccgggcac gctgtcccgc gcgggggcga cggcaacctc gtgcatcacg aggttgaggt
    22381 cgacaccgtc gtgcacccac gagggatgcg gcgcgaaatc ggagatccac gccgcggtgg
    22441 gcaccgagag tcctcgctgc cgtcgcagcc actgcaggcc ggtactgccc atcggatagg
    22501 tcgagagcac cagatcgggc cggacgcggt cgatcgacgg cgcgagaccg cgcccgctcc
    22561 aggcgccgat gacccgcttc gcggccgtgg cgaaccagcg gtgatgccac atcgaggagt
    22621 aaaagaagtc gtagagccac ggcagttttt ccacacacgt cttgtaaatg cgtcggaacg
    22681 cggggccggt cgccgtgccc atcgtctcca gcacgtcgac ccagtgcact tcgataccgg
    22741 gccacagtcg ctcggcggcc tcccgcagtg ccctgcccgt cgcgttgtgt ccctcgccca
    22801 tgtcggccga cacgatgagc agacgctccg gtcttctcgg ctctccgctc ccagtcgtcg
    22861 tcatcaccac ccgttggtcg gcgatcaccc cggtcttgcc ccaagcctgc cacgttcggc
    22921 gccatcgcgg gagttcggac acggcggagc caccaccgag acttgcccac gcggtgaatc
    22981 cttcacgggt gaggcaacga agccctggat gtttcactgg atggtgggat tttcggtgcc
    23041 gcgtccactt cggacgctcg gagtcagccg ctctgcttgc gggccagcag agcgagtgtg
    23101 aacagcaggc ggtcgcgtgg ccgcgacacc ttgcggccgg tcgccgattc gatgcgttgc
    23161 agccggtaga tcaccgtgtt gcgatggcag tacagccgct gtgccgcgtg ggtgggggag
    23221 ccaccgcatt cgatcgtcgc ttcgagagtc ttgaacatcg tctcccgttc cggctccggc
    23281 agcgccagca gatcaccgaa agccacccgc tgaagccggg gagcgagctg cgggctgccg
    23341 acgagcagcg cctcaggcag ccggtcgtcg aggtaggcga ccccgttggc gggaagggtg
    23401 cgggccgcga tctgcgcgag cgtgtacgcg tcggcgatgt cggcgagccg gtgcaccacc
    23461 ggtgaacatc ccacccttcc gtgcgcggaa gcgccgagca cgtccagtac ggccgagggg
    23521 gcccgttcac cgagcacgac gaggccgacg atgtcggacg gcctgacgtg ccacgacgag
    23581 aggatcccgt gggccgccag tacatcccgg ggtgagcgca gcggatcctc gcctgggacg
    23641 tcgatgggcg cgacgacaca cagcagtgga ccggtggcgg gcaggccgag cgcgctcgcg
    23701 gcttcctcgg cgagcgcggt gtccctgcct cttccctcaa gcagtgcgtt gagaaacgcg
    23761 tgccgcctgc tcagttcctg gctccgcagc cgggattcct caagccggta ggcgtcgacg
    23821 agtgccgaag agctggaatc gatcacgcgc cacacgtatc ccgccgcgtc gagcagggcg
    23881 tggtcgtagt acccggcgaa gcgctcgcgc gaggtcgcga gcaacccctc ccagatgacc
    23941 ctgccgccga gccggtaggc gcggagcacg gcttccagcg gaaccccttg gcgtgccctc
    24001 agccgcccgg tctccatgga cgtgtcctgg ggatcctcgc cgtcgggcac gttgccgccg
    24061 agggactgga taccgcgctc gatgttgcag cgcaggttct ccctcagctc gtcgggagcg
    24121 gtgacaccga gttgcgcgta ggcgggttcc cgttgcaaca ccatgatcgt cagccggtcg
    24181 gcgagacttt ccaggttgtc gagcagaacg cggctgagtt tgtgcagcgc gtcccgtgcg
    24241 ggctccgagc agtcgagcgc accgcttcgc cctgccgacg atgtcatcag gcgacgatgg
    24301 cacggactac aacgcgccgt ccaccggatc cgggcagtga gcccataaat cggacacatc
    24361 tttgggctcc gcgcctatgg ccgggattgg gcgccgcgca tcactcttaa ggcgtgtctg
    24421 ataaatctct gccgtgcgag cggggatcag cgtggttcct cgcaaggcgg agggaagtcc
    24481 tcgtaccggg tcgtactcgg gctttccgac aacgcggcga ggggacacgc tggccccgca
    24541 gcaggcaacg ggtttgtcag acacgcctta gggccttcgc gaagagggtg ccccgcgtcg
    24601 gcggcactcg accccaatgg cgggaggcgt ggtcgtgacg ttgccggaca catccgaaac
    24661 ccggttcgcc gacgctggat ccgctccgcc gccactgttc accgccaccg gggtcacggt
    24721 gcgattcggc gggctgaccg cgctcgacac ggtgtcgctg gccgcgcggc cacacgaggt
    24781 gcacggtgtc atcggcccca acggagcggg caagaccacg ttgttcaacg tctgctgtgg
    24841 tttcgtcgag ccggacgaag gtgtcctgcg atggcgggga gatccggtag gcgggctcag
    24901 accacaccag ctcgccggta tggggatcgc gagaaccttg cagggactgg gtttgttcgc
    24961 agggctcacc gtgctggaga acgtcatggt cggcgcggat cggttccggc gcaccggatt
    25021 cggctccgcg ttgctggcac ttccccgttc cgccggtgac gagcggaggt tgcgggaacg
    25081 ggcgatggcg gcgatggccg agctgggact cgccgacgcc gcgagcgcga tgcccgcgag
    25141 cctgccctac ccggtgcgca agcgggtcgc gttcgcgaga gcgctcgccg ccgaccccga
    25201 gctgttgctg ctcgacgaac ctgcgagcgg gctcggtgcc gccgacatcg ctgagctcgg
    25261 cgaactggtg cgcggtctcg cctcccgcat gtcggtggtg ctggtcgacc accacatgga
    25321 cctcgtgatg gcggtgtgcg atcacatcac cgtgctcgac ttcggcagga tcgtcgcccg
    25381 gggaaccccg gccgaggtca aggacgatcc cgccgtcatc gacgcctacc tcggcgagga
    25441 agccgaccgg agtggagacc atggctgacg gcgggcgcga ccgtgaactc gacatcaggg
    25501 gactcaccac gagatacggc cccgtcacgg cactggacgg cgtgagcgtg ctcgcgaggc
    25561 cgggcgaggt caccgccgtc ctcggagcca acggcgcggg caaaaccacg ttgctgcgca
    25621 ccgtttccgg tctggtcaag ggcagtgacg gcgcggtgct gctcggcgga agggacctgg
    25681 ccggagcacc cgccgagacg atcgcgagag cgggtgtggc acacgttccc gaaggccgtg
    25741 gcgtcatcac cgaactgacc gtcgaggaga acctgaggct cggcgaacta ctcggcagcg
    25801 cgcgaagagg caaggccgac aagaacgagc ggctcgcctc cgtctacggc atgtttcccc
    25861 cgctggcaca gcgaaggcgg caggtagcca actcgttgtc cggaggggag cggcagatgc
    25921 tcgtcatcgg aagagcgctg ttgtcggagc cggaggtgct gctgctcgac gagccttcgc
    25981 tcgggctcgc gccgagggtc gtcgc
//
