LOCUS       NZ_CP016353            21572 bp    DNA     circular CON 03-MAY-2024
DEFINITION  Prauserella marina strain DSM 45268 chromosome, complete genome.
ACCESSION   NZ_CP016353
VERSION     NZ_CP016353.1
KEYWORDS    RefSeq.
SOURCE      Prauserella marina
  ORGANISM  Prauserella marina
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Prauserella.
REFERENCE   1  (bases 1 to 6851918)
  AUTHORS   Ruckert,C., Albersmeier,A., Jiang,C.-L., Jiang,Y., Kalinowski,J.,
            Winkler,A. and Zotchev,S.B.
  TITLE     Complete genome sequence of Prauserella marina DSM 45268, isolated
            from ocean sediment of the South China Sea
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6851918)
  AUTHORS   Ruckert,C., Albersmeier,A., Jiang,C.-L., Jiang,Y., Kalinowski,J.,
            Winkler,A. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUL-2016) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 33.7x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002240355.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 02:59:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,595
            CDSs (total)                      :: 6,536
            Genes (coding)                    :: 6,497
            CDSs (with protein)               :: 6,497
            Genes (RNA)                       :: 59
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 39
            CDSs (without protein)            :: 39
            Pseudo Genes (ambiguous residues) :: 0 of 39
            Pseudo Genes (frameshifted)       :: 14 of 39
            Pseudo Genes (incomplete)         :: 31 of 39
            Pseudo Genes (internal stop)      :: 1 of 39
            Pseudo Genes (multiple problems)  :: 6 of 39
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:50:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1282639
            Orig. end                         :: 1304211
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP016353.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21572
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21572
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21572
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11572](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11572)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    354..368
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    complement(494..505)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.15"
                     /tool="antismash"
     misc_feature    complement(820..831)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(834..848)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.79"
                     /tool="antismash"
     gene            complement(884..1558)
                     /locus_tag="BAY61_RS05910"
                     /old_locus_tag="BAY61_05870"
     CDS             complement(884..1558)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030104.1"
                     /locus_tag="BAY61_RS05910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05870"
                     /product="response regulator transcription factor"
                     /protein_id="WP_091799467.1"
                     /transl_table=11
                     /translation="MIRVLLVDDQALIRGGFRALLDAEDDIEVVAEAADGEEGAAAAAA
                     HRPDVALIDIQMPVADGIEATRRIAADPELAGVHVVMLTNYGFDEYVFNALRAGATGFL
                     VKDIEPADLVHSVRVAARGDALLAPSITRTLISEFVAAPPSAGVSTHLAELTNREREVV
                     ALVARGLSNAEIAGHMVISPLTAKTHVSRAMVKLHARDRAQLVVFAFESGLVKPRGGER
                     SH"
     gene            complement(1555..2721)
                     /locus_tag="BAY61_RS05915"
                     /old_locus_tag="BAY61_05875"
     CDS             complement(1555..2721)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013222881.1"
                     /locus_tag="BAY61_RS05915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05875"
                     /product="sensor histidine kinase"
                     /protein_id="WP_091799470.1"
                     /transl_table=11
                     /translation="MGAADTGAAHRWRSRPFDAALAASVTVLVLVDALTGQARPGALDY
                     VLLVISSLALVARTRAPRAVLAISLVANLVYTLQADPGPIAAAPALIAVYTVVSLGHRV
                     LGIAVVAPLIVFAFAQNLAELDDGLSATQAIQDALLPVGWFFAVLVLGEVTRHRRAYLR
                     QVEQRAAEAERTREEAALHRASEERLRIARELHDSLTHQISIITVQAGVAVHLARKRGI
                     EVPEALVAVQDASREAGRELRATLEVLRADRTERHQDTGLARLAELVGKAGVSATVTVE
                     GKRRPLPAEVDRAAYRIVQEALTNVSRHAAGASATVHIGYLEGEVTVRVEDDGSEGEAN
                     AATTTSPGGVGLIGMRERVNALGGTLHAAPREHGGFRVEATLPTVVTA"
     misc_feature    complement(2305..2307)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2793..3767)
                     /locus_tag="BAY61_RS05920"
                     /old_locus_tag="BAY61_05880"
     CDS             complement(2793..3767)
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019819127.1"
                     /locus_tag="BAY61_RS05920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05880"
                     /product="sugar-binding domain-containing protein"
                     /protein_id="WP_091799473.1"
                     /transl_table=11
                     /translation="MSRRSRTVSLTDSVQAATIAHRFYVRGHSKLDIAKDYSISRFKVA
                     RILDWAREIGIVKVTFDLPFPIDPGLSGELAAAYGLRHAFVLERASQPEGRPELRRRIG
                     ALAASVLSELATKDDVIGLSWARSVNVMTEQITSLPRCAVVQLCGVQAGMDMRDRSVET
                     VSGLARVSGGDAYPIFAPLVLPDRRTTETLRRQPGIAETFGQFRNITKAVVSIGAWQEN
                     ESTVYDSLSPSERDSITKRGAKAEVAARLFDAEGNALSTGLAHHVLAISHEELRQVPEV
                     IALGYTTPKAEAIDAVLRSGMVSTFITDADAARRALELAAARG"
     gene            3895..4914
                     /locus_tag="BAY61_RS05925"
                     /old_locus_tag="BAY61_05885"
     CDS             3895..4914
                     /NRPS_PKS="Domain: PKS_ER (16-190). E-value: 6.2e-09.
                     Score: 27.3. Matches aSDomain:
                     nrpspksdomains_BAY61_RS05925_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421808.1"
                     /locus_tag="BAY61_RS05925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05885"
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_091799476.1"
                     /sec_met_domain="ADH_N (E-value: 4e-34, bitscore: 115.3,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 4.6e-16, bitscore:
                     57.5, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAAIVDQPGTIRVGDVPDPKPAERQVVVKVGACGICGTDLHIAD
                     GHFPPTPYPIVPGHEFAGEIVELGPGVPGDWRIGDRVAVDPSLFCGYCTPCRSGHGNLC
                     ANWGATGDTVDGAFAEYVAVPSANCYRMPEGMTWQQGALVEPVSCAVHGVRRVGVEAGE
                     RFLVMGAGTMGLIMQQLLQRAGASVTVVDRNTARLARATELGAVAVAGDAADLADEKFD
                     AAADCTGAVPAIEAAFDALRRGGRLLVFGVAPEEARVALSPFRIYNDEITVVGSMAVLN
                     SFGTALDLVAAGAVDTDALLTDTLSLERYPDALALMRSGAGLKVQVIPGGGNDAHTAR"
     aSDomain        3943..4464
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BAY61_RS05925_PKS_ER.1"
                     /evalue="6.20E-09"
                     /label="BAY61_RS05925_PKS_ER.1"
                     /locus_tag="BAY61_RS05925"
                     /protein_end="190"
                     /protein_start="16"
                     /score="27.3"
                     /tool="antismash"
                     /translation="VPDPKPAERQVVVKVGACGICGTDLHIADGHFPPTPYPIVPGHEF
                     AGEIVELGPGVPGDWRIGDRVAVDPSLFCGYCTPCRSGHGNLCANWGATGDTVDGAFAE
                     YVAVPSANCYRMPEGMTWQQGALVEPVSCAVHGVRRVGVEAGERFLVMGAGTMGLIMQQ
                     LLQRAGASVTV"
     gene            4895..6262
                     /locus_tag="BAY61_RS05930"
                     /old_locus_tag="BAY61_05890"
     CDS             4895..6262
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011874261.1"
                     /locus_tag="BAY61_RS05930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05890"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_091799478.1"
                     /transl_table=11
                     /translation="MPTPLGRRRRKPLIAVLLSTLLLFVTGCAGAGAIGAGGQTLVIAI
                     VANPQMNDAIALSDRFEREHPGVNLKFVSLPENQARAKITASTATEGGEFDVVMISNYE
                     TPQWAANGWLENLQPYIDRSEGYDGDDFIPSIRESLSYQDSMYAVPFYGESSFLAYRED
                     LFQQAGLTMPERPTWQQIADFAAKLDDKANGIAGICLRGKPGWGESLAPFTTVVNTFGG
                     RWFDENWNAQLTSPEFTEAANFYVNLVREHGEVGASSAGFSECGNRYGQGQAAMWYDAT
                     VMAGTNEDPASSKVVGKSGYVAAPVSTTDASGWLYTWSLAMPKVTEHKQAAWEFMRWMT
                     DKQFVQLVGEEFGWNRVPPGCRQSTYEIPEYAEAARAYAQPTLDGIRDARQEKVMAEPV
                     PYPGIQFVGIPEFQDLGTRVSQQLSAAIAGQKSVEEALQQSQEYAETVGKAYQETR"
     gene            6259..7191
                     /locus_tag="BAY61_RS05935"
                     /old_locus_tag="BAY61_05895"
     CDS             6259..7191
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010694798.1"
                     /locus_tag="BAY61_RS05935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05895"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_091799481.1"
                     /transl_table=11
                     /translation="MTTTAAAPPSASETAQRPQGRKGGSPWKRRAPLLPALLFVIAVTQ
                     IPFLVTVFYSFQSWNLVRPGSQHFVGFQNYIDVFADSQFRGAMLNTVVLTVVCVFVSML
                     LGLGLALLLDRKFTGRGVVRTLIITPFLILPAAGALLWKTTMFDPVYGLLNFVFGGETD
                     WLSEFPLASVMTQVIWQWTPFMTLLILAGLQAQSKEVLEAAQVDGAGRGRTFLYITLPQ
                     LSRYLQLAALLGAIYIVNSFDAIYLMTQGGPGTASTNLPFYIYQRAFEGFDVGQSSAMG
                     VIVVVLTLIVATFALRLMFRTFDVSGGVK"
     gene            7188..7997
                     /locus_tag="BAY61_RS05940"
                     /old_locus_tag="BAY61_05900"
     CDS             7188..7997
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005462043.1"
                     /locus_tag="BAY61_RS05940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05900"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_091799484.1"
                     /transl_table=11
                     /translation="MRLGRISLTAFTWLVAILFVFPLIWMVLTAFKQEADAYTDPPRLF
                     FTPTLDQFAGVFERGFLPYLANSGFVTVVSTLAVLVLGIPAAYALSLAPVKGTKNALGF
                     FLSTKMLPIVAAIIPLYVISQNVQLLDNVWALIILYTAMNLPLAVWMMRSFFLEVPKEM
                     IEAARVDGATLPTLLSRIVLPVVAPGIAATALICVIFSWTEFFYAINLTAARAGTVPVF
                     LSGFITSEGLYWAQLSAAALLASLPVMIVGWIAQNHLVRGLSMGAVK"
     gene            complement(8056..8904)
                     /locus_tag="BAY61_RS05945"
                     /old_locus_tag="BAY61_05905"
     CDS             complement(8056..8904)
                     /EC_number="6.3.2.6"
                     /GO_function="GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019819136.1"
                     /locus_tag="BAY61_RS05945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05905"
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="WP_176879589.1"
                     /transl_table=11
                     /translation="MAVVKHIHAGKVRDLYQDGDDILLVASDRVSVYDVTLPTPIPDKG
                     ALLTRLSLWWFELFRDVVPNHVLSATDVPDEFAGRAIRCRPLEMVKVECIARGYLTGLG
                     LREYQKQGTVSGVALPDGLVEGDRLPEPIFTPTTKADVGHDEFITFDDVVAQVGRELAE
                     RLRELTIEIYRRGAEHAATKGIIVADTKLEFGIAADGTLTLGDEVLTSDSSRFWPAGEW
                     EPGRPQHSFDKQFVRDWATSTGWDKTPPGPEIPANIVTATRERYREVYERLTGTDWSPT
                     R"
     gene            9155..9964
                     /locus_tag="BAY61_RS05950"
                     /old_locus_tag="BAY61_05910"
     CDS             9155..9964
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007026826.1"
                     /locus_tag="BAY61_RS05950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05910"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_094168480.1"
                     /transl_table=11
                     /translation="MALPIHTAQQEGSTQPNIARITDYWLDGAHHDDADQRVADNISVC
                     APYMPYLVRSQRALLGRMVRHLLGEGITQFLDLGSGIPTRDHVHEVVQSVDPSGKVVYV
                     DIDPHVVAVGRDVLAGNDNATIVQADFRDHDAVFATPEVARLIDPEQPLAILMIEAFVH
                     ISDEDGPAGIVSGYRDRVSTGSYLAISHCSENEDLLAAYQMFERMALGAPPIVNLRSRE
                     ELTSYFARLDLIEPGEVPIHLWRPESDDEVDRNPDQVQMHAGMGRKL"
     gene            complement(10001..11572)
                     /locus_tag="BAY61_RS05955"
                     /old_locus_tag="BAY61_05915"
     CDS             complement(10001..11572)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012796325.1"
                     /locus_tag="BAY61_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05915"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_091799486.1"
                     /sec_met_domain="T2TS (E-value: 1.5e-87, bitscore: 292.9,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSPAVWPESTGKAVTDLLSEMTEDDRGRFSPSVYETGRLVSMAP
                     SLSGHDRRVRYLLDEQRPDGSWGGPGRYDVVPTLSATEALLAESRRSGCSPSVDSAAMR
                     GIDVLRNRLPRNDSLPDTVAIEIIVPGLVHDINSRLSERNVPTLPVPSGTNGDLLIALR
                     AAVESGTALPEKLWHSLETIGEPARRARFVKPVEGRIVGCSPAATAVWLGDDVIAENRH
                     PSIGYLRDVQDPAVAAVPVAAPLALFERSWVLSTLADCGIEFTAPSALVDSLHEAFGPH
                     GAAGGLGLPADADDTASALYALARLGSPRSPRPLWEYEADDHFSTFPEERTPSTTTNAH
                     VLQALGASVSPDPQEKAHCAAAAAKVTAWLVEQQRPDGTWADKWHASPLYSIACCATAL
                     ARYGGTKGRPAVTKAVDWLLGAQRADGSWGRWEGTAEETAFAVRTLLATTANEENDAVA
                     IAAARGCAFLLANIENTRHPALWHDKDLYTPLRIIETEMLGALHLAKSNDKVVRRVAEQ
                     SARIGA"
     gene            complement(11875..12720)
                     /locus_tag="BAY61_RS05960"
                     /old_locus_tag="BAY61_05920"
     CDS             complement(11875..12720)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (30-264). E-value:
                     1.1e-28. Score: 92.4. Matches aSDomain:
                     nrpspksdomains_BAY61_RS05960_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020642197.1"
                     /locus_tag="BAY61_RS05960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05920"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_091799507.1"
                     /sec_met_domain="PF00561 (E-value: 1.2e-22, bitscore: 79.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7e-17, bitscore:
                     61.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDQSSIEQLTVTTEAGAFDAIASGPAEGRPVLLLHGFPEAALEW
                     EHQVATLGGHGYRAVAPDQRGYSPSVRPENVADYGVDVLVGDVLAVADALGWRRFDLVG
                     HDWGAAVGWWAAAEHPDRLRSFTAVSTPHPSALARAIRSDEDQAMRSAYLTEWRQSSTE
                     QRMLANNAEALRRMFEWKVPLSRVEDYVLRLSEPGALSAALNWYRAGRPRAEAGKVAVP
                     TLYIWSTEDVAFGSTAAFDTENWVSGPYAFHMLEDVTHWIPEEVPEALSALLLEHLAAR
                     "
     aSDomain        complement(11929..12630)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BAY61_RS05960_Abhydrolase_1.1"
                     /evalue="1.10E-28"
                     /label="BAY61_RS05960_Abhydrolase_1.1"
                     /locus_tag="BAY61_RS05960"
                     /protein_end="264"
                     /protein_start="30"
                     /score="92.4"
                     /tool="antismash"
                     /translation="PVLLLHGFPEAALEWEHQVATLGGHGYRAVAPDQRGYSPSVRPEN
                     VADYGVDVLVGDVLAVADALGWRRFDLVGHDWGAAVGWWAAAEHPDRLRSFTAVSTPHP
                     SALARAIRSDEDQAMRSAYLTEWRQSSTEQRMLANNAEALRRMFEWKVPLSRVEDYVLR
                     LSEPGALSAALNWYRAGRPRAEAGKVAVPTLYIWSTEDVAFGSTAAFDTENWVSGPYAF
                     HMLEDVTHWIPE"
     gene            complement(12751..14019)
                     /locus_tag="BAY61_RS05965"
                     /old_locus_tag="BAY61_05925"
     CDS             complement(12751..14019)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020639327.1"
                     /locus_tag="BAY61_RS05965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05925"
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="WP_245865846.1"
                     /transl_table=11
                     /translation="MMEQALSDALWQLDDRELAALLARRESALRQAHAEMLAAVGEAER
                     RGLAKNLGYRDSVAMLRTELRVSAREAHARLADALATQARRSPEGEELPAPLVATARLL
                     NTGGLGREHLREITRIFARCPDTVSGQERADAEQTLLDLAAQASPEAVRAAGHRLIAYW
                     DSERQPVEEPELAAPTREFRYRYRRNGQLEFTGNLDPETGATLEGLFGPLAKPRPKDDD
                     GHPDPRTMAQRQGDALAEIIDSAARAEDLTVQGGERAVLTATITLAELEDRTRQSSTEL
                     PGYSTPEQLRRLACEAQVIPAIFGTDGEVLYLGRSSRHASKAQRRALALRDKGCAFPGC
                     DRGPKWCVPHHIVWWDHGGNTDIDSMVLVCAHHHRLIHHTDWEVRVNSADRLPEFVPPA
                     WLDPARRPRRNTAHLIGKHPRAA"
     misc_feature    complement(14056..14071)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: strong, score: 27.38"
                     /tool="antismash"
     misc_feature    14057..14070
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 22.52"
                     /tool="antismash"
     gene            complement(14313..15572)
                     /locus_tag="BAY61_RS05970"
                     /old_locus_tag="BAY61_05930"
     CDS             complement(14313..15572)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335287.1"
                     /locus_tag="BAY61_RS05970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05930"
                     /product="cyclopropane-fatty-acyl-phospholipid synthase
                     family protein"
                     /protein_id="WP_091799511.1"
                     /transl_table=11
                     /translation="MAQGELGRVFGRFLNTDAPVSVTTYEDSSIGNPEASAHIEIRSPA
                     ALSYVLSAPGELGLARAYVTGHLDVSGELYDVLKYMSSLIDGLTVADRLWILRQLGARH
                     FRPMPVPSEEAPNRIRRALQGLRHSKSRDSAAISQHYDVSNRFYELVLGPSMAYTCACF
                     PSTEATLEQAQFHKFDLVCRKLGLKPGMRLLDVGCGWGGMVAHAAEHYGVQALGVTLSR
                     EQAQWAQKNIVSRGLADRAEVRHLDYRDVKEGQFDAISSIGLTEHIGARNLPSYFRFLA
                     SKLKDKGRLLNHCITRPSNREPNHTGPFIDRYVFPDGELEGVGAIISAMHDHGFEVRHS
                     ENLREHYARTLAGWCANLDANWTEAVGEAGVRRARVWALYMAASRLAFERHKIELQQVL
                     GVKVGANGDSAMPLRPDWGV"
     misc_feature    complement(15555..15557)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15588..16991)
                     /locus_tag="BAY61_RS05975"
                     /old_locus_tag="BAY61_05935"
     CDS             complement(15588..16991)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009152846.1"
                     /locus_tag="BAY61_RS05975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05935"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_091799514.1"
                     /transl_table=11
                     /translation="MALKNNGAGDRSPVGNRSTTAAGYAERVAALRTRLAAQPPGAPVR
                     LAKRTSNLFRPRAGTTGPGLDVSGFTHVLDVDPVARTADVEGMVTYEQLVDATLPHGLM
                     PLVVPQLKTITVGGAVTGLGIESSSFRNGMPHESVLEMDLLTGAGDIVLARRDNEHSDL
                     FFGFPNSYGTLGYALRLRIELEPVRPFVRLEHIRYSDTVEYFDAVNRACRDRAADFVDG
                     TVFGPREMYLTLGTFTGEAPETSDYTWLDIYYKSIRERTIDHLPVRDYLWRWDTDWFWC
                     SRALGAQNRLVRLLAGPKLLRSQTYWKVVTFERHHQWLAGLNRALGKPRREAVIQDIEV
                     PVGKAADFLDFFHREIPISPVWMCPVRQRDSDRTWPLYQFDPGSLYINFGFWATVPLAP
                     GQREGSNNRLIEKTVTELGGRKSLYSESFYDPDTFWQLYNGKTYRALKDRYDPGHRLLD
                     LYDKCVKAR"
     gene            17163..17621
                     /locus_tag="BAY61_RS05980"
                     /old_locus_tag="BAY61_05940"
     CDS             17163..17621
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BAY61_05940"
                     /product="hypothetical protein"
                     /protein_id="WP_143021343.1"
                     /transl_table=11
                     /translation="MSSSVGDLSSDRPAQPSADAVANAALELQRARSALESGDGDLRAL
                     HEAVKGAARLTRSLAATVDRLVRYTPGTVENRKVARDLVADLRALRSCLTAGAALIDPA
                     VDDLRDLADSAGSPTGGAGVGHSIGEPFDPDADFAARWEEWVSARPGT"
     gene            complement(17630..19000)
                     /locus_tag="BAY61_RS05985"
                     /old_locus_tag="BAY61_05945"
     CDS             complement(17630..19000)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009152849.1"
                     /locus_tag="BAY61_RS05985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05945"
                     /product="FAD-binding protein"
                     /protein_id="WP_091799521.1"
                     /transl_table=11
                     /translation="MPDSFERSDLPTLEGDILDGEASLAAAARDWGHIVQARPRLVVRP
                     SSAADVSAVLEFASSRGVPVAARGAGHSPFGQAQSEGGIVLDMSGMATVHEGTGNELLV
                     DAGARWQQVLSASLPRGLTPPVLTDYLELTVGGTLAVGGIGGATHRYGAQTDTVTELEV
                     VTGEGELKRCSAENNSDLFDAVRAGLGHCGVITRATLRLRPARQRARKWKLTYDSLDDY
                     LTDQRTAVGDSRFDHLEGRVVLGDDSGEWRYVLEGTSYFSLPDEPDEAALLAGLSFDHE
                     GRETEDRTYHGFLDRMAESQTVLSADGSWFRPHPWITVLAPDDGIADVVTETLAETSGD
                     DLGDSGVVLLYPLRAETLGTPLLRKPATDIGWLFAVLRTGDPYDVTATGRMLELNAAVA
                     ERARLVEGAVYPVNALPMTPQEWRDHFGDAWEAFAAAVKKYDPKNVLARGQRVFEAP"
     gene            complement(19092..19673)
                     /locus_tag="BAY61_RS05990"
                     /old_locus_tag="BAY61_05950"
     CDS             complement(19092..19673)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009152850.1"
                     /locus_tag="BAY61_RS05990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05950"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_091800737.1"
                     /transl_table=11
                     /translation="MKGKQDQVLDAAIRVLGTKGTRALTHRAVDAEAGVPAGSTSNYFR
                     TREALLSGLLGRLSELETASWREFAEALDAEAMADTGRFAEAVGGLAGELAGPARTFTL
                     ARHAVFLEAAVNERLRQQIVLRRAELESQGTRWLRALGSSRPSADFWAIMALLDGLLLH
                     ETTAPGAAFAPSPAIGALLRGLSGDWPERT"
     gene            19829..19990
                     /locus_tag="BAY61_RS32760"
     CDS             19829..19990
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BAY61_RS32760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_170140075.1"
                     /transl_table=11
                     /translation="MREPDTEPGVELSERSLLSTVHNGSPMPRDPSGGLPVFDEDEELE
                     PIIVRGRE"
     misc_feature    complement(21540..21554)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
ORIGIN
        1 catcggtttc ggtgtagaaa ccgggtaccg gtttcccgtt gcggtacagc gccatcgttc
       61 ccttgtcgaa gtcgaaggtg gccgcgagga agacccactc atccttgggg agcaggcgct
      121 gccagtcctg gctcgccgcg aacgtctgcg accggccgtc gtcgagccgc cttcccagcg
      181 ccaccagccg caactcaccg tccacattga tgagttcgag cagtgccctg accccgtggc
      241 cgtccgagtt tccggccaga atgcccgcga gcccgacggc gttgaagtag tcgccggggt
      301 cgggcgtggt cgaatccggt ttcggatggt cgccggtcat cttgaaccag cccatcaccg
      361 ttgtcgacgt ggtggcgttg aatgcgttca gcgtcggtac gccgccgggg gagtacaccc
      421 cggccttcca atcgtcgttg cccgcgacgc tctcgtcgat ctgcttggtt tgcagcgcct
      481 ttcgcgctcc ggggtaagcg ttgtcggcga cccgcatcgc cgccgcgccg ttgatcaatt
      541 cgaggtcggt acccgatcgg cccagatccc gttccagccc ggggtttccc gcgaccgggt
      601 gatcgaagtc gtagtaggag acgagatgcg gcgcgagcgt gggaaagacg gcaggtttgc
      661 cgggagacgc gtgcgcgacc ggtaccgcga ggctcgcgcc gacgaggacc gccgcgagcg
      721 cggcgcccgt cctcaccacc ttgctcgcgc gccgtgtcct tttcccaccc agctttccgg
      781 gcagcgacat ctgctcacct cacgggatcg acgtgttgtg aaagcgcttt cagttctcga
      841 aagcagaagc ctacccagga tttcttgtgc ggtccagagg tgatcagtgc gatcgttcgc
      901 cgccgcgtgg cttcaccagc ccggattcga acgcgaacac gacgagttga gcgcggtcgc
      961 gcgcgtgcag cttgaccatg gccctgctga catgggtctt ggccgtcagc gggctgatca
     1021 ccatgtgccc ggcgatctcc gcgttggaaa gtcccctcgc caccagcgcg acgacctcgc
     1081 gttccctgtt ggtcagttcg gcgaggtgcg tgctcacacc agccgaggga ggcgccgcga
     1141 cgaactcgct gatcagcgtg cgcgtgatgg aaggagccag cagggcgtca ccccgcgcgg
     1201 cgacccgcac ggagtgcacg aggtccgccg gctcgatgtc cttgacgagg aaacccgtcg
     1261 cgcctgcccg aagcgcgttg aacacgtact cgtcgaaacc gtaattggtc agcatgacga
     1321 catgcactcc ggcgagttcg ggatcggccg ctatcctcct cgttgcctcg atcccgtcgg
     1381 cgaccggcat ctggatgtcg atcaacgcga cgtcggggcg gtgcgcggcg gccgcggccg
     1441 cgccttcctc gccgtcagcg gcctcggcga cgacctcgat gtcgtcctcc gcgtcgagca
     1501 atgcgcggaa accgcccctg atcagcgcct ggtcgtcgac gaggagcacc cggatcatgc
     1561 ggtgaccacc gtcgggaggg tggcctcgac cctgaaccca ccgtgctccc ttggcgccgc
     1621 gtgcagcgtg ccgccgagag cgttgacccg ttcccgcatt ccgatcagtc cgaccccgcc
     1681 gggcgatgtg gttgtcgcgg cgtttgcctc tccctcgctg ccgtcgtcct cgacgcgtac
     1741 cgtcacctcg ccttcaaggt aaccaatgtg gacggtcgcc gacgcaccgg ccgcgtgcct
     1801 gctgacattg gtgagcgctt cctgcacgat ccggtaggcc gccctgtcga cctcggccgg
     1861 cagcggccgt cgtttcccct cgaccgtcac cgtcgcggag accccggctt tgccgaccag
     1921 ttcggcgagt cttgccaggc cggtgtcctg gtgccgctcg gtccggtccg cgcgcaacac
     1981 ctccagtgtc gctcgcagct ctcttcccgc ctccctgctc gcgtcctgaa cggcgacaag
     2041 cgcctcgggt acctcgattc cccgcttgcg ggcgaggtgc acggccactc cggcctgaac
     2101 ggtgatgatg gagatctgat gggtcagcga atcgtgcagc tctctcgcga tgcgcagccg
     2161 ttcctcgctt gccctgtgca gcgccgcttc ctccctggtt cgctcggcct cggccgcccg
     2221 ctgctccacc tggcgcaggt aggccctgcg gtgccgggtc acttcaccga gtaccagcac
     2281 ggcgaagaac cagccgacgg gcaataacgc gtcctggatg gcctgcgtcg ccgagagccc
     2341 gtcgtcgagt tcggcgaggt tctgcgcgaa ggcgaacacg atgaggggtg cgacgacggc
     2401 gatacccagc acccggtgcc ccaggctcac caccgtgtac acggcgatga gcgcgggagc
     2461 cgcggcgatc gggccgggat cggcctggag cgtgtagacg aggttcgcga cgagactgat
     2521 cgcgagcacg gctctcggtg ccctcgtcct cgcgacgaga gcgagggaac tgatcacgag
     2581 caggacgtag tcgagcgcgc cgggccttgc ctgcccggtc agcgcgtcca cgagcaccag
     2641 gaccgtcacg ctcgcggcga gtgcggcatc gaacgggcgg gatcgccacc tgtgcgcggc
     2701 ccccgtatca gcggctccca tgagggcagc ctaaaccgga atcccctcat tctcgttcgg
     2761 tccggggagt acttcccccg gagtagacga cgtcagccgc gtgcggcggc cagttcgagt
     2821 gccctccgtg ccgcgtcggc gtcggtgatg aacgtcgaca ccatgcctga acgcagtacg
     2881 gcgtcgatcg cctcggcctt cggcgtggtg tagcccagcg cgatgacctc aggtacctga
     2941 cgcagttcct cgtgactgat ggccagtacg tggtgcgcga gcccggtgga gagcgcgttt
     3001 ccctccgcgt cgaacagccg cgccgcgacc tcggccttgg cgccgcgctt ggtgatcgag
     3061 tccctttcgg acgggctgag cgagtcgtag acggtcgatt cgttctcttg ccacgccccg
     3121 atgctcacga cggccttggt gatgttccgg aactgaccga aggtttcggc gatgcccggc
     3181 tgcctccgca gcgtctccgt cgtgcgccgg tcggggagga ccagcggcgc gaagatcggg
     3241 taggcgtctc ctccggagac ccgcgccagc ccgctcaccg tctccacgga ccggtcccgc
     3301 atgtccatgc ctgcctgcac gccgcacaac tgcacgaccg cgcagcgggg gagggacgtg
     3361 atctgttcgg tcatcacgtt cactgacctc gcccacgaca acccgatcac gtcgtccttc
     3421 gtggccagtt cgctcagcac actggccgcg agcgcgccga tgcgccgtcg cagctcgggc
     3481 cttccctctg gttgactcgc tcgttcgagc acgaacgcat gtcgcaggcc atacgcggcc
     3541 gcaagctcgc ccgacaaccc gggatcgatg ggaaacggca gatcgaaggt caccttgacg
     3601 atgccgattt cccttgccca gtcgagtatc cgggccacct tgaacctgct gatcgagtag
     3661 tccttcgcga tgtcgagctt cgagtgccct cgcacgtaga accgatgggc gatcgtggcc
     3721 gcctgaaccg aatcagtaag gctcaccgtg cgactccgtc tgctcatatg agcactatag
     3781 ctggaaatct gagcgaaagg ttgacgtaac accagcgttt atccttcaat gcctgcacat
     3841 gtcgttgtag cgatgaatga acgacgctca tatgagcggt gaagggtggg tggcatgcgc
     3901 gccgcgatcg tcgaccagcc ggggaccatc agggtgggtg atgtacccga ccccaagccc
     3961 gccgaacggc aggtcgtcgt caaggtcggc gcgtgcggca tctgcggaac cgacctgcac
     4021 atcgccgacg ggcatttccc gccgaccccg tatccgatcg tccctgggca cgagttcgcc
     4081 ggtgagatcg tcgaactcgg gcctggtgtg cccggtgact ggcggatcgg tgaccgggtc
     4141 gccgtcgacc cttcactgtt ctgcggctac tgcactccgt gcaggtcagg tcacggcaac
     4201 ctgtgcgcca actggggcgc caccggggac accgtcgacg gagccttcgc cgaatacgtc
     4261 gccgtccctt cggccaactg ctaccgcatg cccgaaggca tgacctggca gcaaggtgcg
     4321 ctcgtcgagc ccgtctcctg cgcggtgcac ggtgtcagga gggtcggcgt agaggccggt
     4381 gaacggttcc tggtgatggg ggcgggaacg atgggcctca tcatgcagca gttgctgcaa
     4441 cgggctggtg cctcggtgac cgtcgtcgac cgcaacaccg cgagactggc cagggccacc
     4501 gaactcggtg ccgtcgccgt cgccggcgac gccgccgacc tggccgacga gaagttcgac
     4561 gccgcggccg actgcaccgg cgccgtcccc gccatcgagg cggccttcga cgcgttgcgc
     4621 agagggggaa ggctgttggt cttcggcgtc gcgcccgaag aggcgcgagt ggcgctctca
     4681 ccgtttcgga tctacaacga cgagatcacc gtcgtcggct cgatggcggt actcaacagt
     4741 ttcggcaccg cgctcgacct cgtcgcggca ggcgccgtcg acacggacgc gttgctcacc
     4801 gacacgcttt cgctcgaacg ttatcccgac gcactggcgt tgatgcgcag tggcgccgga
     4861 ctcaaggtcc aagtgatccc gggaggcggc aacgatgccc acaccgctcg gtaggcggcg
     4921 caggaaacca ctcatcgcgg tactgctgtc cactctgctg ctgttcgtca ccggctgcgc
     4981 gggtgccggt gccatcggtg cgggcgggca gacgctcgtc atcgccatcg tggccaaccc
     5041 gcagatgaac gacgccatcg cgctgtccga ccggttcgag cgcgagcatc caggcgtgaa
     5101 cctcaagttc gtctcgctgc cggaaaacca ggcgcgcgcc aagatcaccg cctcgaccgc
     5161 gaccgagggc ggcgagttcg acgtggtgat gatcagcaac tacgagactc cacagtgggc
     5221 ggcgaacggc tggctggaga acttgcagcc ctacatcgac cgcagcgagg gttacgacgg
     5281 cgacgacttc atcccgagca ttcgcgaatc gctgtcctac caggactcga tgtacgcggt
     5341 gccgttctac ggggaatcct cgttcctcgc ctaccgcgag gacctcttcc agcaggcggg
     5401 gctgaccatg cccgagcgcc cgacctggca gcagatcgcc gacttcgcgg cgaagctcga
     5461 cgacaaggcc aacggcatcg ccgggatctg ccttcggggc aagccagggt ggggcgaaag
     5521 cctcgcgccg ttcaccaccg tcgtgaacac cttcggcggc cggtggttcg acgagaactg
     5581 gaacgcccag ctcacctcgc ccgagttcac cgaagccgcg aacttctacg tcaacctggt
     5641 gagggagcac ggcgaggtcg gcgcgtccag cgcgggattc tccgaatgcg gcaacaggta
     5701 tggccagggg caggccgcca tgtggtacga cgcgacggtc atggccggta ccaacgagga
     5761 cccggccagc agcaaggtcg tcggcaagtc cggctacgtc gccgcacccg tgtccacaac
     5821 ggacgcgagc ggctggctct acacctggtc gctcgcgatg cccaaggtga ccgagcacaa
     5881 gcaggcggcg tgggagttca tgcgctggat gaccgacaaa cagttcgtcc agctcgtcgg
     5941 tgaggagttc ggctggaaca gggttccgcc gggttgcagg cagtcgacgt acgagattcc
     6001 cgagtacgcc gaagcggcga gggcatacgc gcaaccgaca cttgacggta ttcgcgacgc
     6061 acgccaggaa aaagtcatgg cggaaccggt gccctatccc ggcatccagt tcgtcggcat
     6121 ccccgagttc caggacctcg ggaccagggt gagccagcag ctctccgcgg ccatcgcggg
     6181 gcagaagtcg gtcgaagagg cactccagca gtcacaggag tacgccgaga cggtcggcaa
     6241 ggcataccag gagacccgat gacgacgacg gcggcggctc ctccctcggc aagcgaaacc
     6301 gcgcaacgac cgcagggccg caagggcggt agcccgtgga agcgcagagc ccctctgctg
     6361 cccgcgctgc tcttcgtcat cgccgtgacg cagattccgt ttcttgtcac ggttttctac
     6421 tcgttccagt cctggaacct ggtgcgtccc gggtcgcaac acttcgtcgg gttccagaac
     6481 tacatcgacg tgttcgccga cagccagttc cgcggagcga tgctcaacac cgtcgtactc
     6541 acggtggtgt gcgtgttcgt ctcgatgctg ctcggtctcg ggctcgcgtt gctgctcgac
     6601 cggaagttca ccggcagggg tgtggtgcgc acgctgatca tcaccccgtt cctgatcctt
     6661 ccggccgcgg gcgcgctgct gtggaagacg accatgttcg acccggtgta cgggctgctc
     6721 aacttcgtat tcggcggtga gaccgactgg ttgtcggagt tcccgctcgc ctcggtgatg
     6781 acccaggtca tctggcaatg gaccccgttc atgacgctgc tcatcctcgc cgggctgcaa
     6841 gcgcagtcga aggaagtact cgaagccgcg caggtcgacg gcgcgggcag gggaagaacc
     6901 ttcctctaca tcacgttgcc acagctcagc cgctacctgc agctggccgc gctgcttggc
     6961 gcgatctaca tcgtcaactc gttcgacgcc atctacctga tgacccaagg tgggccaggt
     7021 acggcgagca ccaacctgcc gttctacatc tatcagcgag ccttcgaggg cttcgatgtc
     7081 ggtcagtcct ccgcgatggg cgtcatcgtc gtcgtactca ccctcatcgt cgcgaccttc
     7141 gcgctgcgcc tgatgttccg gaccttcgat gtgagcggag gcgtgaaatg agactcggcc
     7201 ggatatcgct gaccgcgttc acctggctgg tcgcgatcct gttcgtcttc ccgctgatct
     7261 ggatggtgct gacggcgttc aaacaggaag ccgatgccta caccgacccg ccgagactgt
     7321 tcttcacccc gaccctcgac cagttcgcgg gagtgttcga gcgcgggttt ctgccctacc
     7381 tcgcgaactc ggggttcgtg acggtcgtgt ccaccctcgc cgtgctggtg ctgggcatcc
     7441 ccgccgcgta tgcgctgtcc ctcgcgcccg tgaaggggac gaaaaacgcg ctgggcttct
     7501 tcctgtccac gaagatgctg ccgatcgtcg ccgcgatcat cccgctctac gtgatatcgc
     7561 agaacgtgca gctgctcgac aacgtgtggg cgttgatcat cctctacacg gcgatgaacc
     7621 ttccgctggc cgtgtggatg atgcgctcgt tcttcttgga ggtacccaag gagatgatcg
     7681 aagccgcaag ggtcgacggc gccaccctgc cgacgctgct ttcccggatc gtgctacccg
     7741 tcgtggcacc cgggatcgcc gcgaccgccc tgatctgcgt gatcttctcc tggacggagt
     7801 tcttctacgc gatcaacctc acggcggcac gtgccggaac ggtgccggtg ttcctttccg
     7861 gattcatcac cagcgaggga ctgtactggg cacaactctc cgctgccgct ctgctggcgt
     7921 cgctgccggt gatgatcgtg ggctggatcg cgcagaacca cctcgtccgc ggcctctcca
     7981 tgggcgcggt gaagtaacgg tggcccggtg ccgaaagcgc ggacccgctc gcgccttcgg
     8041 cacccgtccg cgctttcagc gtgtggggga ccagtccgtt ccggtgaggc gctcgtagac
     8101 ctcccggtag cgctctctcg tcgcggtgac gatattcgcg gggatctcgg ggccaggcgg
     8161 ggtcttgtcc cagccggtac tggtcgccca gtccctcacg aactgcttgt cgaacgagtg
     8221 ctgcggcctg cccggctccc attcgccggc aggccagaac cgcgacgagt ccgaggtgag
     8281 tacctcgtcg cccaaggtca gcgttccgtc ggccgcgatt ccgaactcca gcttggtgtc
     8341 ggcgacgatg atgcccttcg tcgccgcgtg ttcggccccg cgacggtaga tctcgatcgt
     8401 cagctcccgc agccgttcgg cgagctcgcg cccgacctgc gcgacgacgt cgtcgaaggt
     8461 gatgaactcg tcgtgcccca cgtccgcctt cgtggtgggc gtgaagatgg gctcgggaag
     8521 tcggtcgccc tccacgaggc cgtccggtag cgcgactccg gataccgttc cctgcttctg
     8581 gtactcacgc aggccgaggc ccgtcaggta gccgcgggcg atgcactcga ccttgaccat
     8641 ctccaatgga cggcaccgaa tcgctctgcc cgcgaactcg tccggaacgt cggtggccga
     8701 caggacgtga ttcggtacga cgtcacggaa gagctcgaac caccacagcg agagccgggt
     8761 cagcaaggca cccttgtcgg gaatcggtgt cggcaacgtc acgtcataga ccgaaacccg
     8821 gtctgacgcg acgaggagaa tgtcgtcgcc gtcctggtag agatcccgga ctttgccagc
     8881 gtggatgtgc ttcacgaccg ccatcgtacg ggcgctcggt ggcggttcgg cctgaccctg
     8941 aggagcgaac aactcactcg aacgagtggc ctcaagctcg ttcgtgcaag cggaagcggc
     9001 gacgacctgg gccgaaacag gcagcgtccg gccaggtggg caacgtcgac ctcctgccgt
     9061 cccgtcccgc cattcgcagt agaatcaggt gccctgtgcg gcggaagatc gctaggatga
     9121 gcaacgggtc aggacccgag gaggcgtact cagagtggca ctccccatcc acaccgctca
     9181 gcaagaaggc tcaacccagc ccaacattgc gcggatcacc gattactggc tggatggtgc
     9241 ccatcacgac gacgccgacc agcgggtggc cgacaacatc tcggtctgcg cgccgtacat
     9301 gccctacctc gtccgttcgc agcgggcgct gctgggcaga atggtgcggc accttctcgg
     9361 tgagggcatc acccagttcc tcgatctcgg ctccggtatt cccacccgtg accacgtgca
     9421 cgaggtcgtg caatccgtcg acccctccgg caaggtcgtg tacgtcgaca tcgaccccca
     9481 tgtcgtcgcc gtcggacgcg atgtgctggc aggtaacgac aacgccacca tcgttcaggc
     9541 cgacttccgt gaccacgacg cggtcttcgc cacgcccgag gtcgcgaggt tgatcgatcc
     9601 ggagcagccg ctcgcgatcc tgatgatcga ggctttcgtc cacatctccg acgaggacgg
     9661 acccgcaggg atcgtgtcgg gctaccgcga tcgtgtgagc actggcagtt acctggcaat
     9721 ctcgcattgt agtgagaatg aggatctgct cgcggcttat cagatgttcg agcgcatggc
     9781 gctcggtgcg ccgccgatcg tgaatctacg ctcacgtgag gagctgacga gttacttcgc
     9841 ccggctcgat ctcatcgagc cgggcgaagt acccattcac ctgtggcgtc ccgagtccga
     9901 tgacgaagtc gaccgcaacc cggaccaggt gcagatgcac gccgggatgg ggcgcaaact
     9961 ctgaccgtcg gacgctggcc agcgggtgcg gcgcggttca tcacgccccg attcgagccg
    10021 actgctcggc aacccgccgg acgaccttgt cgttcgactt cgccaaatgc agggcgccca
    10081 gcatttcggt ctcgatgatc cgcagcggtg tgtagaggtc cttgtcgtgc cacagcgcgg
    10141 gatgccgtgt gttctcgatg ttggcgagca ggaaggcgca gccccgcgcc gccgcgatcg
    10201 cgacagcgtc gttctcctcg ttcgcggtgg tggccagcaa agtccggacc gcgaaggccg
    10261 tttcctcggc cgtaccctcc cagcgtcccc acgaaccgtc ggcacgctgg gctcccagta
    10321 gccagtccac ggccttcgtc acggccggcc tgcccttcgt gccgccgtaa cgggcgaggg
    10381 cggtagcgca acaggcgatg gagtaaagcg gcgacgcgtg ccatttgtcg gcccacgtac
    10441 cgtccggacg ctgttgttcc accagccacg cggtgacttt ggccgccgcg gcggcacaat
    10501 gggccttttc ttgcgggtca gggcttaccg aggctcccag tgcttgcagg acgtgcgcgt
    10561 tggtcgtcgt cgaaggggtc cgttcctcgg ggaacgtgct gaagtggtcg tccgcctcgt
    10621 actcccacaa agggcgcgga gaccgcggac ttccgaggcg agccagcgcg tagagcgcac
    10681 tcgccgtgtc gtcggcgtcg gccgggaggc cgagcccgcc ggccgcgcca tgaggtccga
    10741 atgcctcgtg cagactgtcc accagcgccg acggtgccgt gaactcgatg ccgcaatcgg
    10801 ccagtgtgga cagtacccac gaccgctcga acaaggccaa gggcgccgcg acgggaaccg
    10861 cggctacggc aggatcctgg acatcgcgca ggtagccgat cgagggatgg cggttctcgg
    10921 cgatcacgtc gtcacccagc cagaccgccg tcgcggcggg cgaacagccc acgatgcggc
    10981 cctcgaccgg tttgacgaag cgcgctcgcc gtgcgggttc gccgatcgtt tccaaggaat
    11041 gccacagttt ttccggcagc gcggttcccg actcgacggc ggcccgcagc gcgatcagca
    11101 ggtcgccgtt ggttccagag gggaccggca gtgtgggcac attccgttcg gagagccggc
    11161 tgttgatgtc atggacgagc ccgggaacga tgatctcgat cgcgacggtg tccggaaggg
    11221 aatcgttgcg cggcaatcga ttcctgagga cgtcgatccc tcgcatagcc gccgagtcga
    11281 ccgagggcga acagccagat ctgcgcgact cggccagcaa ggcttccgtg gcgctgagtg
    11341 tgggtacgac gtcgtaacgc cctgggcctc cccagctccc gtccggtcgc tgttcgtcga
    11401 gcaggtatcg cactcttcgg tcgtgtccgg acagtgaggg agccatggac accagtcggc
    11461 cggtctcgta caccgatggt gagaacctgc cacgatcgtc ttcggtcatc tccgacaaca
    11521 ggtctgtgac ggctttccca gtcgattccg gccacacagc gggcgagtcc atgaagcact
    11581 ccttggcgtt gccagctttg agatatccag ggtcacccgg gtgagtgagc gaaactccaa
    11641 agtagcatcc cggccaaagg tgtcacatcg gacatgatcc ggatggagca gcgttgtgtt
    11701 ggtcaaccgg ccacgttgaa ctgtttggat gaagcggcgg aactggtgct gcctccgggg
    11761 acatcgttgc tgtcgtcgcg atagcgaatg cggtatgtgc cagtggtttc ccaaggtacg
    11821 gtccaccgat ggtcaccgtg gccgcgacga tgtcctgtca gcgcaaggca gtgctcagcg
    11881 agccgcgaga tgttccagca gcaatgcgct caacgcttcg ggcacctcct cggggatcca
    11941 gtgggtcacg tcttcgagca tgtgaaaggc gtagggtccg ctgacccagt tctcggtgtc
    12001 gaaggccgct gtcgagccga aggcgacatc ctcggtgctc cagatgtaca gcgtcggcac
    12061 agccaccttg cccgcctccg cacgtggccg cccggcccgg taccagttca gcgcggcact
    12121 gagtgcccca ggttccgaga gccggagtac gtagtcctcg actctgctga gaggaacctt
    12181 ccactcgaac atccggcgca gcgcctcggc gttgttcgcg agcatgcgtt gttcggtcga
    12241 cgactgacgc cattcggtca ggtaggccga gcgcatagcc tggtcctcgt cggaacggat
    12301 cgcccgcgcg agcgcggagg ggtgcggtgt ggacacggcg gtgaacgaac ggagccggtc
    12361 gggatgttca gcagccgccc accagcccac ggcggcgccc cagtcgtggc cgacgaggtc
    12421 gaaccggcgc cagccgagtg cgtcggcgac cgcgagcacg tcgccgacga ggacgtcgac
    12481 gccgtagtcg gcgacgttct cgggccggac cgagggggag tagcccctct ggtcgggtgc
    12541 gacagcccgg tatccgtggc cgccgagtgt cgcgacctgg tgttcccact ccagggcagc
    12601 ctcgggaaaa ccgtgcaaca acagcaccgg gcgcccttcg gcggggcctg acgctatggc
    12661 gtcgaaggcc ccggcctcag tggtgacggt gagttgttcg atgctggact ggtcggtcat
    12721 tgccggaacc ctagccgtgt ccatggcggg tcatgccgcc cgtgggtgct tgccgatgag
    12781 atgcgccgtg ttgcgcctgg gtcttcgtgc cggatcgagc caggccgggg gaacgaactc
    12841 cggtagccgg tcggcggagt tgacgcgtac ttcccaatcg gtgtggtgta tcagccgatg
    12901 atggtgcgcg cagacgagca ccatgctgtc gatatcggta ttaccaccgt gatcccacca
    12961 tacgatgtgg tgtggtacgc accatttggg accacggtcg caaccgggga aggcgcatcc
    13021 cttgtcccgc aacgccaacg cccttcgctg ggctttgctg gcgtgccggg aggatcggcc
    13081 gaggtacagg acctcgccgt cggttccgaa gatggcgggg atgacctgcg cctcgcaggc
    13141 cagcctccgc agttgttccg gcgtggagta accgggcagt tcggtcgagg actgccgggt
    13201 gcggtcttcg agttcagcca aggtgatcgt cgccgtgagt acggcgcgct ctccaccctg
    13261 gaccgtcaga tcctctgctc tggccgccga atcgatgatc tcggcgagtg cgtctccctg
    13321 acgttgtgcc atggttcgcg gatcgggatg tccgtcgtcg tccttcggcc gcggtttcgc
    13381 cagcgggccg aacaagcctt cgagtgtcgc accggtttcg gggtcgaggt ttcccgtgaa
    13441 ttcgagttgc ccgtttctgc ggtaccggta ccggaactct cgcgtcggcg cggcgagttc
    13501 gggttcctcg accggttggc gttcggagtc ccagtacgcg atcagccgat gccccgccgc
    13561 gcgtaccgcc tccggggacg cctgtgccgc gaggtcgagg agcgtctgct ccgcgtccgc
    13621 ccgttcctgg ccggagacgg tgtcggggca ccgcgcgaag atccgcgtga tttcgcgaag
    13681 atgctcgcgt ccgagtccgc cggtgttcaa aaggcgggcg gtcgcgacaa ggggtgccgg
    13741 tagttcctca ccctcgggcg atcgtcgtgc ttgggtcgcc aaggcgtcgg ccagccgggc
    13801 gtgcgcttcg cgtgcggaaa cacgcagttc ggtacgcaac atggccacgg aatcgcgata
    13861 acccaggttt ttggccagcc ctctcctctc ggcttcgccg acggcggcca gcatttcggc
    13921 atgtgcttgc cgcaatgccg actcgcggcg ggccagtagc gccgccagtt cccgatcgtc
    13981 gagttgccac aacgcatcgg atagtgcctg ttccatcatc ctccccccaa tacactcacc
    14041 aacctaccac ccacttcgaa cacacgttcg accacttttg cgtgaatccc tttgcgcgga
    14101 accgcgaaac ggtagtgaaa gcaccattcg caccacgaac caccagaggc acacccaaac
    14161 ccgccgctca aaccagaaca cacacgaaca cgccctggaa cgcccggaca acgaacgaac
    14221 ccggcaaaag gcaggcggcg cgcgggaacc gctgtcccga acccgcctgc cgtcgagccg
    14281 ggagcgccct cgcctcacat cacatcaggt gctcacacac cccagtccgg ccgcaaaggc
    14341 atcgccgaat cgccgttcgc gccgactttg accccgagaa cctgctgtag ctcgatcttg
    14401 tgtcgctcga aggcgagccg tgaggccgcc atgtagagcg cccacacccg tgccctgcgg
    14461 actcccgctt ccccgacggc ttccgtccag ttcgcgtcga gattcgcgca ccagcccgcc
    14521 agcgtgcgcg cgtagtgttc gcgcaagttc tcggaatgcc ggacctcgaa accgtggtcg
    14581 tgcatggccg agatgatcgc gccgacgcct tcgagttcgc cgtcgggaaa gacgtaccgg
    14641 tcgatgaacg gtccggtgtg gttgggttcc ctgttgctcg gtctcgtgat gcagtggttg
    14701 agcagcctgc ctttgtcctt gagtttggag gcgaggaacc ggaagtacga gggtaggttg
    14761 cgcgcaccga tgtgttcggt cagcccgatc gaggaaatcg cgtcgaactg gccttccttc
    14821 acgtcccggt agtcgaggtg gcgtacttcg gcccggtcgg cgagtcctct tgagacgatg
    14881 ttcttctgtg cccactgggc ctgttcccgc gacagcgtca cgccgagcgc ttgcactccg
    14941 tagtgttccg ccgcgtgagc caccatgccg ccccagccgc aaccgacgtc gagcagccgc
    15001 attcccggct tgaggccgag tttgcggcag acgaggtcga acttgtggaa ctgggcctgt
    15061 tcgagtgtcg cttccgtgct gggaaagcag gcgcaggtgt aggccatgga ggggccgagc
    15121 acgagttcgt agaaccggtt ggagacgtcg tagtgctgtg agatcgcggc gctgtccctc
    15181 gacttggaat gcctcagccc ttggagtgct cgcctgatcc tgttcggggc ctcctcggag
    15241 ggaacgggca tcggccggaa gtgccgggcg ccgagctgcc gcaggatcca cagccggtcg
    15301 gcgaccgtga ggccgtcgat gaggctcgac atgtacttga gcacgtcgta caactcgccg
    15361 ctgacgtcga gatgaccggt gacgtacgca cgggcgagcc cgagttcgcc gggagccgac
    15421 agcacgtagc tcaatgcggc cggagagcgg atctcaatgt gagccgacgc ttccggattg
    15481 ccgatcgagc tgtcttcgta cgtggtcacc gagacggggg cgtccgtgtt gagaaaccgg
    15541 ccgaataccc gccctaattc gccttgtgcc atggttgctc acctcactta cctcgctttg
    15601 acgcatttgt cgtagagatc cagcagcctg tgtccggggt cgtagcggtc cttcagggcc
    15661 cggtatgttt ttccgttgta gagctgccag aacgtgtccg ggtcgtagaa gctttccgag
    15721 tagagggatt tgcgtccgcc cagttcggtc accgttttct cgatcagcct gttgttgctg
    15781 ccttctcgct ggcctggcgc gagtggaacg gtcgcccaga acccgaagtt gatgtacagc
    15841 gagccggggt cgaattggta gagcggccag gttcggtcgc tgtctcgttg ccggacgggg
    15901 cacatccaca ccgggctgat cggaatttcc cggtggaaga aatcgaggaa atcggcggcc
    15961 ttgccgaccg gtacctcgat gtcctgaatc acggcttccc gtcgcggttt tcccagtgcg
    16021 cggttgagtc cggccagcca ctggtggtgt cgctcgaacg tgacgacctt ccagtaggtt
    16081 tgtgagcgca gcagcttcgg cccggccagc aggcggacga gccggttctg cgcgccgagc
    16141 gcgcgcgagc accagaacca gtcggtgtcc catcgccaca ggtagtcgcg cacggggaga
    16201 tggtcgatcg tgcgttccct gatcgacttg tagtagatgt ccagccacgt gtagtcgctc
    16261 gtttccggag cttcgccggt gaaggtaccc aacgtcaaat acatttcccg gggtccgaac
    16321 acggttccgt cgacgaagtc cgctgccctg tcccggcagg cgcggttcac cgcgtcgaag
    16381 tattcgacgg tatcgctgta acggatgtgt tcgagccgga caaaggggcg aacgggttcg
    16441 agttcgatcc gcaaccgcag cgcgtagccg agtgtgccgt aggagttggg gaagccgaag
    16501 aaaaggtcgc tgtgttcgtt gtcccgcctg gccagcacaa tgtctcccgc gccggtcagc
    16561 aggtccattt ccaggaccga ttcgtgtggc attccgttgc ggaacgagga cgattcgatg
    16621 ccgagccccg tgacggctcc accgacggtg atggttttga gctgggggac gaccagcggc
    16681 atgagcccgt gcggcagcgt cgcgtcgaca agctgctcgt aggtgaccat cccttccacg
    16741 tcggcggtcc tcgcgaccgg gtcgacatcg agcacatggg tgaatccgga tacgtcgagt
    16801 cctgggccgg tggtaccggc gcgtggtcgg aagaggttcg aggtgcgttt cgcgagcctt
    16861 accggtgccc cgggtggctg agcggcgagt cgcgtgcgca atgcggccac ccgctcggca
    16921 tatccggcgg ccgtcgtcga acgattccca acgggcgaac ggtccccggc gccgttgttt
    16981 ttcagcgcca tgaacccatg atcgctctgg ttggccaacg ctgccagtgg cggcgaccgg
    17041 gtttcacccc gcacgccacc gaatcgtccg attgaccttg ggtcggcgcg ggcactatac
    17101 aaattgttgg tcggggaaag ctacttgggc cgtggctgtg gctgcggtcc gaaccgaagt
    17161 gggtgagttc ttccgtgggc gacctttcgt ccgaccgtcc tgcccagccg agcgccgacg
    17221 ccgtcgcgaa cgcggcactc gaattgcagc gcgccagaag tgcgctcgaa agcggggatg
    17281 gtgacctgcg ggcgttgcac gaggctgtga agggggcggc gaggttgacc agatcgcttg
    17341 ccgcgaccgt cgaccggctc gtgaggtaca cccctggcac cgtcgaaaat cgcaaggtgg
    17401 cgcgcgatct cgtggcggat ctcagggcgc tgcggagttg cctgacggcg ggtgcggcgc
    17461 tcatcgatcc agccgtcgac gatttgcggg atctggccga cagcgccggt tctcccaccg
    17521 gtggggccgg cgtcggacac tcgataggcg agccgttcga ccccgacgcc gatttcgccg
    17581 cgagatggga ggagtgggtt tccgcgcggc cggggacgtg agcttccggt tacggcgcct
    17641 cgaacacccg ttgcccgcgg gcaagtacgt tcttcgggtc gtacttcttg accgccgcgg
    17701 cgaatgcctc ccacgcgtcg ccgaagtgat cccgccattc ctgcggggtc atcggtagtg
    17761 cgttgaccgg gtagacggcg ccttcgacca gccgcgcgcg ttcggcgacg gcggcgttga
    17821 gttcgagcat ccttccggtg gcggtgacgt cgtagggatc gccggtacga agtaccgcga
    17881 acagccaccc gatgtcggtt gccggtttcc gcagcagcgg cgtgccgagg gtttcggcgc
    17941 gcagcgggta gagcaggacg acgccggaat cgccaagatc gtctccgctg gtctcggcca
    18001 gagtctcggt gacgacgtcg gcgattccgt cgtcgggggc gagcacggtg atccaaggat
    18061 gggggcggaa ccagcttccg tcggcactga gcaccgtttg gctctctgcc atgcggtcga
    18121 ggaagccgtg gtaggtcctg tcctcggttt ccctaccttc gtgatcgaag gaaaggccgg
    18181 ccagcagggc cgcctcgtcc ggctcgtcag gcagcgagaa gtagctggtg ccttcgagga
    18241 cgtaccgcca ttcgccgctg tcgtcgccga gtacgacccg gccttcgagg tggtcgaacc
    18301 gggaatcgcc gacggcggtg cgctgatcgg tgaggtagtc gtcgagtgag tcgtaggtca
    18361 gtttccactt gcgcgcgcgt tgccgggcgg gccgcagccg cagggtggcg cgggtgatga
    18421 caccgcagtg gccgagcccc gctcgcaccg cgtcgaacag gtcgctgttg ttctcggccg
    18481 agcagcgttt gagctctcct tcaccggtga cgacctccag ttcggtgacg gtgtcggtct
    18541 gtgctccgta ccggtgggtc gcgccgccga tgccgccgac ggcgagggtg ccgccgactg
    18601 tgagttccag gtagtcggtc aggaccggag gagtgagacc gcggggaagg ctcgccgaca
    18661 gcacctgttg ccagcgtgcg ccggcgtcga cgagcagttc gttgccggtg ccctcgtgga
    18721 cggtggccat cccggacatg tcgaggacga tgccgccttc ggattgagcc tggccgaacg
    18781 gtgagtggcc cgctcctcgc gcggcgacgg ggacaccccg cgaactggcg aattcgagca
    18841 cggccgacac gtcggcggcc gaggacggcc tgacgacgag acgcggtctc gcctgcacga
    18901 tgtgccccca gtcccgtgcc gccgcggcga ggctcgcttc gccatcgagg atgtcaccct
    18961 caagggtcgg caggtcggag cgttcgaacg agtccggcat ctgccggact ctagcggttg
    19021 accccttcga cctggcaggt atggctgagg tgctgttttc ctcgaaaggg ccgctgcgac
    19081 gccccttcgg gtcaggttcg ttccggccag tccccgctga gtccccgcag cagcgcgccg
    19141 atggcggggg agggggcgaa cgcggcgccg ggggcggtgg tctcgtggag cagcagcccg
    19201 tcgagcagcg ccatgatcgc ccagaagtcg gcggagggcc gggacgagcc cagcgcgcgc
    19261 aaccaccgtg tcccctgtga ctcgagttcc gccctgcgca ggactatctg ttgccgcagg
    19321 cgctcgttta cggcggcttc gaggaagacg gcgtgcctgg cgagggtgaa cgtcctcgcg
    19381 gggcccgcga gttctccggc gagaccgccg acggcttcgg cgaagcgccc ggtgtcggcc
    19441 atggcctcgg cgtcgagagc ttcggcgaat tcccgccagc tcgcggtttc cagttcgctc
    19501 agtctgccga gcaggccgga aagcagggct tccctcgtcc ggaagtagtt cgatgtcgac
    19561 ccggccggga caccggcttc cgcgtcgacg gccctgtggg tgagtgcgcg ggtgcccttg
    19621 gtgccgagta cgcgaatggc cgcgtccagt acctggtcct gtttgccctt cacgggttca
    19681 cggtagcggg caaggggttc ttcctttcgc gcgccggtgg tgctttccac tgaatccgcc
    19741 gtcagccttt caggttggga tcgccccgtg tttttcccgt tttccgctcg ggtatatcaa
    19801 gatcgtgggg ttgtgagagg agtgcccgat gcgcgaaccc gacaccgagc ccggagttga
    19861 actctccgag cgctcccttc tttccaccgt ccacaacgga tcgccgatgc cccgggaccc
    19921 ttccgggggt ctgccggtct tcgatgagga cgaagaactg gagccgatca tcgtgcgcgg
    19981 cagggaatag cacgaagccg cccctcgcat gccgccccgt gatcgtgtag cgtgctacat
    20041 cgacgtgagg ggtggtggtc atgattcggc aggacaggga gctgctcgcg cggctctcct
    20101 cggtcaacac gcggctcggc gaggccgtgg tggagttgtt gcaccgtcag gacggcggcc
    20161 ttttgcctgc cgaaggactg cgcgctcttg gtcaccatct ccagggaatt accgctgacc
    20221 tgctgaatcg tgccgatgag ctggatgccg tcgtgatcga ccggccgccc tcgcgcgagg
    20281 taacgtcccg gtggccgccg accgccaccg gaggagagtc gatgaacacc gtgcccacct
    20341 cgccggaacc ggacgacgaa ctcgcgctgc gatacctcag gcaggcggag agcgcggcgg
    20401 gcaccgctcc ggacgccgaa ccacgcgacg tcggacgcat cggtgtcgtc ggcgcgggca
    20461 cgatgggcgc gggtatcgcg acggtgttcc tgcaggccgg gtttccggtc accgtggtcg
    20521 agcagagcgt ggaggcgctg gagcgcggtg tcgagcgcat cagcgccatc caggacaagg
    20581 cggtggcgag gggtaaagcc gatcgcgccg aggccgaccg caggctcgcg gccctgacag
    20641 cgggcaccga tcaggcatcg ctcggcgact gcgacgtcgt ggtcgaggcg gtgttcgagg
    20701 acatggaggt gaagaaggcg ctgttgtcgc ggctggccac gatcgtcaaa cccggggcgg
    20761 tcctcgcttc caacacgtcg tatctcgacc tcgacgagct ggccgaagcc agtgggcggc
    20821 cacgggacgt ggtggggctg cacttcttca gtcccgcgca cgtcatgcgg ttgcttgagg
    20881 tggttcgcgg ggcgaagacg ggcgaggaca ccctggccac cgcgttgtgg ctggggcgga
    20941 agacaggcaa gcttcccgtg gtcgccgggg tgtgtgacgg cttcatcggc aaccgcgtct
    21001 acaacgccta ccgcgtccag tgcgagttca tggtcgagga aggtgctttg ccggaggaga
    21061 tcgacgcggc gctggagggc ttcggtttcg ccatggggcc gttcacggtc tgggacatgt
    21121 cagggctcga catcgccaag gccaccaggc agcggcaggc cgcgacgagg gaccccaggg
    21181 agcggatgcc gaaggtgctg gacgtgctgt acgagcgggg gcggctcggc cgaaagacag
    21241 gcgcgggctg gtacgcctac cccgatgacg gggagcgtca ggtcgacccc gccgtgcacg
    21301 aggtgattcg cgcggttgtc gagcggaacg gcgtcgagcc gaggacgttg tcgccggacg
    21361 agatcgtgcg ccgcgcgctg ggagtgatcg tcaacgaggc gatgctcgtg ctggctgacg
    21421 gcatcgccga gcgtgcctcg gacatcgatc tcgtgctcgc caacggatac ggcttcccca
    21481 agaagcgtgg cggcccgctg ttctgggcgc acgatcaccg ggaccaggtc accaccggca
    21541 tcgacgaggc tgagcgggca acgggattcg gg
//
