LOCUS       NZ_CP016353            22697 bp    DNA     circular CON 03-MAY-2024
DEFINITION  Prauserella marina strain DSM 45268 chromosome, complete genome.
ACCESSION   NZ_CP016353
VERSION     NZ_CP016353.1
KEYWORDS    RefSeq.
SOURCE      Prauserella marina
  ORGANISM  Prauserella marina
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Prauserella.
REFERENCE   1  (bases 1 to 6851918)
  AUTHORS   Ruckert,C., Albersmeier,A., Jiang,C.-L., Jiang,Y., Kalinowski,J.,
            Winkler,A. and Zotchev,S.B.
  TITLE     Complete genome sequence of Prauserella marina DSM 45268, isolated
            from ocean sediment of the South China Sea
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6851918)
  AUTHORS   Ruckert,C., Albersmeier,A., Jiang,C.-L., Jiang,Y., Kalinowski,J.,
            Winkler,A. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUL-2016) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Coverage                   :: 33.7x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002240355.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 02:59:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,595
            CDSs (total)                      :: 6,536
            Genes (coding)                    :: 6,497
            CDSs (with protein)               :: 6,497
            Genes (RNA)                       :: 59
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 39
            CDSs (without protein)            :: 39
            Pseudo Genes (ambiguous residues) :: 0 of 39
            Pseudo Genes (frameshifted)       :: 14 of 39
            Pseudo Genes (incomplete)         :: 31 of 39
            Pseudo Genes (internal stop)      :: 1 of 39
            Pseudo Genes (multiple problems)  :: 6 of 39
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:50:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1222384
            Orig. end                         :: 1245081
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP016353.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22697
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="2"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22697
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22697
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12697](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12697)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(57..521)
                     /locus_tag="BAY61_RS05625"
                     /old_locus_tag="BAY61_05585"
     CDS             complement(57..521)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017983594.1"
                     /locus_tag="BAY61_RS05625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05585"
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_091800690.1"
                     /transl_table=11
                     /translation="MTSSTPAKAGADRTAGEAHEPGTSVLLTSQGTTTIASTVVRQIAG
                     LAAREVPGVHALGSGAARAFGALRERVPGGGSSAAQGVSVEVGDKQAAVDLRVVVEYGT
                     PIPALARTVRANIITAIEQMTGLEVVEVNIAVEDIHLADDGEQETTSRVA"
     gene            complement(810..1571)
                     /locus_tag="BAY61_RS05630"
                     /old_locus_tag="BAY61_05590"
     CDS             complement(810..1571)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021604.4"
                     /locus_tag="BAY61_RS05630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05590"
                     /product="anti-sigma factor"
                     /protein_id="WP_091799346.1"
                     /transl_table=11
                     /translation="MNHDFPTLTGAYAVNALTGRERAEFEHHLADCDECASEVEELRAT
                     AAKLGAAVSAEPPEQLRARVLYDVAHTRQEPPSEEQPRVSGRAASRWRGWATKAAVAAA
                     VVGIALAAVFGGIALRQHNELRQAEQRIEQAGTRGADMAAVLHASDVRVLHSAGDGTAA
                     TVVVSAELGKAVFLGERLPTVPEDRVYQLWAMGPSGAHSLGVLAGTDAGAAQPVVGDLP
                     EDTTALGLTAEPSGGSPQPTSDPIMQMALRS"
     gene            complement(1568..2158)
                     /gene="sigK"
                     /locus_tag="BAY61_RS05635"
                     /old_locus_tag="BAY61_05595"
     CDS             complement(1568..2158)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene="sigK"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335935.1"
                     /locus_tag="BAY61_RS05635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05595"
                     /product="ECF RNA polymerase sigma factor SigK"
                     /protein_id="WP_091799349.1"
                     /transl_table=11
                     /translation="MADEAPVAGTAQGQPPSDPQALLVEVGRGDERAFEQLYDLIARPV
                     FGLVQRIVRNAAQSEEVTQEILVQVWRTATHYRPDKGSAMTWVLTLAHRRAVDRVRSEQ
                     SATERETKAGSRSAERSFDEVSESVLARFEQRQVRRCLATLTDLQRESVLLTYYRGYTY
                     REAASLLDSPPSTVKTRLRDGLIRLRDCLRVGS"
     misc_feature    complement(2196..2212)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.23"
                     /tool="antismash"
     gene            complement(2210..3490)
                     /locus_tag="BAY61_RS05640"
                     /old_locus_tag="BAY61_05600"
     CDS             complement(2210..3490)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020672759.1"
                     /locus_tag="BAY61_RS05640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05600"
                     /product="cyclopropane-fatty-acyl-phospholipid synthase
                     family protein"
                     /protein_id="WP_091799352.1"
                     /transl_table=11
                     /translation="MSVIDAETRLAVPPREPDHGPPWEQLGPPPHAPLRAAIAERAFRH
                     AVRSLPVQIALAGGERLGTGESGSPLMRVHRPAAFFHRLGHDGKIGFGEAYLAGDWTSP
                     EPAELLTPFAAKMADLIPRPLQAFRGFVDTNRPASERNTERGARENIRRHYDFSNTFFA
                     SFLDPAMTYSGAPLCPGGDLAEAQDRKLAAVLDLAGVREGSRLLEIGTGWGSLAVVAAG
                     RGAHVTTLTLSAEQRKLAEERIARAGLADRVDIRLRDYREEHGRYDAVVSVEMIEAVGA
                     QYWPTFFRQLDRLLLPGGKAAVQAITMPHDRLLATRESQTWIHKYVFPGGQLPSVKVIE
                     RNVAANTGMTLVERRAFGSGYAETLRQWRQRLNANWPVYWAGDGRPGTDGELPRRMWEF
                     YLAYSEAGFRSGYLDVCQFGLHKPVSR"
     misc_feature    complement(3116..3118)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3487..4212)
                     /locus_tag="BAY61_RS05645"
                     /old_locus_tag="BAY61_05605"
     CDS             complement(3487..4212)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013224817.1"
                     /locus_tag="BAY61_RS05645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05605"
                     /product="DUF1365 domain-containing protein"
                     /protein_id="WP_091800693.1"
                     /transl_table=11
                     /translation="MAAPALYEATVGHTRHIDVGGGFRHRLYLWLVDIDELPRLPWWLR
                     PFTRFDARDHLGRRGAPIRRGLSAWLYEHGVRIGEGRVLMLAHARVLGHVFNPLTVYWC
                     FGEDGRQRCVVAEVHNTYGEAQRYLLFPGEDGFAEASKRFYVSPFLPSRGTYRMWLPCP
                     GERLDLRVELHSEEGPLLTATLEGTRRRASIRNIGTTLLRHPLVPQRVSALIRAHGVAL
                     WARGAPSVAHTKNAAEENR"
     gene            complement(4212..5492)
                     /locus_tag="BAY61_RS05650"
                     /old_locus_tag="BAY61_05610"
     CDS             complement(4212..5492)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009943310.1"
                     /locus_tag="BAY61_RS05650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05610"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_091799355.1"
                     /sec_met_domain="DAO (E-value: 2e-07, bitscore: 29.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQSHDPTKPTVAVIGAGVSGLTAAYLLRKTHRVLLFEADDRLGGH
                     AHTHEVVTGDGSAIGVDSGFIVHNDRTYPQLTRLFSELGVPTQDTEMSMSVSCAGCGLE
                     YAGAKRLGGLFAQPANLAKPVYLRLLAQVRAFHRAANRLLDDPRAPAPGMTIGEFLARG
                     RYSHYFTEHFALPLVSAVWSAGPRISGHYPARYLFEFLRNHGMLSVGGSPRWRTVVGGS
                     RRYVDLLAKNLPFVRTDTPVRAVSRGHDGVQVRTVADEVYPADKVVLATHADDALRLLD
                     SPTPAESGTLGAFGYSDNEAVLHTDAGVLPKARGARASWNYAKPGCSANTDRMVVSYDM
                     NRLLRLAEPADYVVSLGAAGFDERTVLARTAYRHPVFTPDSVAASTRLPALNTGRTAFA
                     GAYHGWGFHEDGCASGVRAAESFGARW"
     misc_feature    complement(5537..5552)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.52"
                     /tool="antismash"
     gene            5660..6445
                     /locus_tag="BAY61_RS05655"
                     /old_locus_tag="BAY61_05615"
     CDS             5660..6445
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020630291.1"
                     /locus_tag="BAY61_RS05655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05615"
                     /product="DUF1295 domain-containing protein"
                     /protein_id="WP_091799357.1"
                     /transl_table=11
                     /translation="MSVTDVLGAVALALGAASAVVVAAFVVALVRRRYDTIDSFWGAGF
                     AVIAVTGFLAEPRGLGSSLVVTALTVCWGTRLSWHIHRRNVAGGEDRRYTEMLGRAKRY
                     PRLRMFCKVYLTQGAVMWFVALPVVLAQRQADELGALAFAGIAVWAFGFAFEVIGDEQL
                     RRFKADPGNKGAVLRHGLWRYTRHPNYFGDACVWWGIYLIAAQHLPGVATVLSPVLMTW
                     LLARGSGKPLMERHLAASKGGYADYVRRTSGFVPLPPKF"
     gene            complement(6442..7308)
                     /locus_tag="BAY61_RS05660"
                     /old_locus_tag="BAY61_05620"
     CDS             complement(6442..7308)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227561.1"
                     /locus_tag="BAY61_RS05660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05620"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_091799360.1"
                     /transl_table=11
                     /translation="MATGPAKTAVEPMSIVAMDQYEQHPLVQDELAHHFLPPTARAMAA
                     VARWPKLREVIRSATEHKFPGLWASMLCRKRYFDDAVTEAVSSGCETVIILGAGLDDRA
                     YRLPALADIPVFEVDLPRNITEKYQRLHALFCSVPKTTTLVPVDFERQNLAEVLGDYGY
                     RADRPTYFLWEAVTQYLTERDVRRTFDFLGTAPVGSRLGFTYVRSDFLSGQNLYDAREA
                     HRQFVTKSHLWRFGMSPDTVTDFLTEYGWHKTEDLGATEFNDRYLEPAHRRLPLTQIER
                     AVSAEKR"
     gene            7709..8224
                     /locus_tag="BAY61_RS05665"
                     /old_locus_tag="BAY61_05625"
     CDS             7709..8224
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944872.1"
                     /locus_tag="BAY61_RS05665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05625"
                     /product="DUF4231 domain-containing protein"
                     /protein_id="WP_091799363.1"
                     /transl_table=11
                     /translation="MKFEPPFPDSLPDTGTLGIIGAANTYAIRLRAFYNSRAVWHRRFY
                     RFSGILVIAAGAGLPVVANLDYGGKELVVSLMGTLVALLTALHAFYRWDQSWMLLRHTE
                     MRLTSAYWAWRAALPATVSDSGAPDPTTVTLTRDFLLALSQIRDQEAVSFFEKLSFPTA
                     TANHVDVR"
     misc_feature    8060..8062
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8206..8997)
                     /locus_tag="BAY61_RS05670"
                     /old_locus_tag="BAY61_05630"
     CDS             complement(8206..8997)
                     /GO_function="GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009944871.1"
                     /locus_tag="BAY61_RS05670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05630"
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="WP_245865830.1"
                     /transl_table=11
                     /translation="MVPTTPAVTASQGGHVPLPCWLTSAPIAHRGCYDAVEHPENSLPA
                     FRRAIELGAPFEFDVQLTSDDEPIVVHDRDFSRVAGTCSAPVADLDLAAVRALRIGPAD
                     LPVPTLDDVLSLVDGAVPLLLDLRRWKAGNAKLERAVADRLRGYRGQTAVQSFDPIAVR
                     RLRKLAPHVPVGQASGSLQSAGKLVGTLGRMMLSNAITRPDFINYELAELPSRAVSFWR
                     GRGIPVIAFTAHSPEEELLARRFADNFLFSGYLPGHYRTST"
     gene            complement(9840..9941)
                     /locus_tag="BAY61_RS32755"
     CDS             complement(9840..9941)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF039607.3"
                     /locus_tag="BAY61_RS32755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_143021341.1"
                     /transl_table=11
                     /translation="MESVLELQGMDADETTTDPAYHTIISYLSLLLC"
     CDS_motif       complement(9879..9941)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MESVLELQGMDADETTTDPAY"
                     /locus_tag="BAY61_RS32755_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9840..9878)
                     /prepeptide="core"
                     /locus_tag="BAY61_RS32755_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="9.00"
                     /molecular_weight="1321.6"
                     /monoisotopic_mass="1320.8"
                     /core_sequence="HTIISYLSLLLC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MESVLELQGMDADETTTDPAY"
                     /leader_location="[9878:9941](-)"
                     /alternative_weights="1339.6"
                     /alternative_weights="1357.7"
     gene            complement(10001..12697)
                     /gene="lanKC"
                     /locus_tag="BAY61_RS05675"
                     /old_locus_tag="BAY61_05635"
     CDS             complement(10001..12697)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016330827.1"
                     /locus_tag="BAY61_RS05675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05635"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_338061450.1"
                     /sec_met_domain="micKC (E-value: 1.3e-293, bitscore: 974.7,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.5e-10, bitscore: 39.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 0.00013, bitscore:
                     19.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTANDIEHSPCGTVRGGVAVEHRYEEFCLADPLFFDEQRGSAAE
                     RFARFTPLPEEGWAERQHGTWRVLHPLGASLPYQGWKIHVSATLDNAEQVLTTVYECLV
                     ERAVTFKHLTDLAVLLARNSKYAPREASGKLVTIYPRDDREFETLVTELDQRIGGQAGP
                     YILSDLRYGDGPLYVRYGGFTERWIDSGGTRVLGIAREDGTLVPDHRGPVFALPDWVEL
                     PEFLAPHLAARSAKSTGDFAYHVNRPLHFSNGGGVYLAEHAREGNQVVLKEARPHAGLD
                     GDKVDAVARLRREHRALTSLTDVPGVPAVYELTPVWEHLFLAMEHRPGVPLHSWLGANY
                     PLTNYRASDSDVAAYTRRALGIADRIGETVSEIHLRGLVFNDLHPANVLVTDDDSVSLI
                     DFELAGPPGPARRPTLGAPGFRAPADRTGFEVDDYALAALRLWLFLPLSALFELAPAKL
                     PEWVRFVEDRFPLPNGYGESILATLRRGTREKDDRDREGRAVGRGTIGHRTTAPVTVLD
                     DPEPDWNLVRKSIAQAILTSATPERPDRLFPGDIEQFRLGGLGFGHGAAGVLHALAVEG
                     LGRSPEHDRWLRDAIDRNRPLAPGFLDGAAGIAYVLHGFGDHDTANALLADARRSIAKT
                     RDHGLANGLAGIGLTLLYLGDGGGESGELGERLVAELESAAPPGRKAKAGLVEGWSGPA
                     LLFTRLFEATGDGEWLVHAERALSRDLAECVPARDGSMQVRDGVKRTLPFLGTGSAGIA
                     MAAMELAKHTSDDGTSVRQLPLLLRACRAEAALQCGLLAGRGGLLATLAAARRYGHDPT
                     AEDAIASHLARLAWHAIPFALPDGDGDDGIAFPGNKLLRLSMDVATGSAGVLLSISTAL
                     DDHSGVLPFLAPVPTVGDDSVIASSPH"
     misc_feature    complement(10340..10342)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(13160..13175)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 20.79"
                     /tool="antismash"
     gene            complement(13197..13724)
                     /locus_tag="BAY61_RS05680"
                     /old_locus_tag="BAY61_05640"
     CDS             complement(13197..13724)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013677189.1"
                     /locus_tag="BAY61_RS05680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05640"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_245865832.1"
                     /transl_table=11
                     /translation="MNPHARNLPYLWLMTTWKEFSISAPVIAEVFTRRHAATKNLCMLA
                     TLRADGFPRISPIEPRFFEDELWLVGMPNTTKFHDLGRDPRFCLHTATVETEPNEGDAK
                     LWGRVRDVQDKEVHARFAEAMFEETGFDLRGQEFEHLYAADLIGASSLVTGDDSLDITI
                     WRPGEPERLVHR"
     misc_feature    13756..13770
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.01"
                     /tool="antismash"
     gene            complement(13762..15219)
                     /locus_tag="BAY61_RS05685"
                     /old_locus_tag="BAY61_05645"
     CDS             complement(13762..15219)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020501836.1"
                     /locus_tag="BAY61_RS05685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05645"
                     /product="trypsin-like peptidase domain-containing protein"
                     /protein_id="WP_245865834.1"
                     /transl_table=11
                     /translation="MTENSPHQHQPQPDQSGPQQTPAEQGDAGSWQPGAPKAHKPSPQE
                     SIAPLVDSPSAQQQRTDDVAEATQEAATPAWGLAAQQQPPHSATGFAGSVPTALAKPKR
                     RVPVSIIATAIIAGLVGGGAALGGNALLSTDSAVPVLTSQPASASNVSSKPGSVEYAAE
                     VAMKSTVDIKVPTGQGTATGTGIILSEDGYVLTNNHVVAGASENGKIQVTAPDGKKYSA
                     SVTGTAPSYDLAVIKLDDADGLTPATLGESSGLKVGQQVAAIGSPEELSNTVTSGIVSA
                     LSRTVTAGDDNGELVVYNGLQTDAPINPGNSGGPLVNLDGQVVGVNSAVEPGQSSNGGL
                     QAYGLGFSIPIDTAKRIANELMQNGEANKPVLGVSGSVNPQGDSTAEGAQLASVQPGSA
                     AEKAGIRQGDVITKLGDTLISSYADLMAQVLKHTPGEEVPVVVKHADGSTETVNVALES
                     AKDTQQTTITPQQQNPFDGDGGFGRGN"
     gene            complement(15441..16691)
                     /locus_tag="BAY61_RS05690"
                     /old_locus_tag="BAY61_05650"
     CDS             complement(15441..16691)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020639029.1"
                     /locus_tag="BAY61_RS05690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05650"
                     /product="beta-propeller fold lactonase family protein"
                     /protein_id="WP_245865836.1"
                     /transl_table=11
                     /translation="MTPVATAVSSGCHGLPLVTSLVMRITGTSVAVAFVATSLLLTGCG
                     SQDSVENAPPADAVEQPAVQEAGAQPPEAKAEEDSERDVYAATRPGNFSPAMEGVLNRV
                     YVPNSVSNTVSIIDPSTFKVIDTIPGGLEPQHVVPSYDFKTLYVTADEVPGGTLTPIDP
                     KTGKAGELIHVQDPYNLYFTPDGKSAIVVAEAYKRLDFYEPHTWRKQESLHIDECAGIN
                     HMDFTKDGKLALVTCEFANRMIVLDVEAKKHVRTFELDQTPHGMPQDSRLSPDGSTFYV
                     ADMHANGIYLFDGDATKQVGFVPTGQGAHGVYFSRDSKRAFITNRGEGSVTILDTGTNK
                     PIDKWHIPGGGSPDMGSVSADGKQLWLSGRHHNEVYVLDTDNGNLLARIPVGSGPHGLT
                     YMPQPGRYSLGHTSNIR"
     gene            complement(16772..17389)
                     /locus_tag="BAY61_RS05695"
                     /old_locus_tag="BAY61_05655"
     CDS             complement(16772..17389)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013226387.1"
                     /locus_tag="BAY61_RS05695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05655"
                     /product="response regulator transcription factor"
                     /protein_id="WP_256327938.1"
                     /transl_table=11
                     /translation="MSTNPPIRVVLAEDQAMVRSAFVSLLDLQPDVTVVAATATGEETL
                     AAVEEHQPDVLVTDIEMPHGSGLDVAVELARRKHPVRILIVTTFARAGYLRRALDASVA
                     GYVLKDAPIGELMVALRRVHAGEQVIASELAVAAWGRPDPLTDRERQLLREVADGAANA
                     EIAARLHLAEGTVRNYLSSAMAKLGARNRTEAAKAASERGWL"
     misc_feature    complement(17315..17317)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17386..18465)
                     /locus_tag="BAY61_RS05700"
                     /old_locus_tag="BAY61_05660"
     CDS             complement(17386..18465)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020665952.1"
                     /locus_tag="BAY61_RS05700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05660"
                     /product="sensor histidine kinase"
                     /protein_id="WP_091799374.1"
                     /transl_table=11
                     /translation="MKPPGRLSRWIHLIYLVNLLWGPIFDRDSGGADWALVAGIVVVFL
                     PMYVASWRWPARARWTGTVPTTVLAALTTPFNAGAAILFVYAAAFAGFSESRRSALRWF
                     IGLSALLSLTSVLSFVPMPWRLYGLIPSLIYLWVIGSLQISWSERERAEVETRMRNARV
                     EHLATIAERERIARDLHDLLGHSLTAIIVRAQLANELLDRSNSRAGSELTDIEDTARTA
                     LSEIRATLAGWRNAGLDAELESAQETLATVGITTRVRRDATLTIVGSTEHELALALREA
                     VTNVARHARATTCHIDVGVVGDDLCLVIADDGVGDGSAPEGNGLTGMRERISALGGRVE
                     KIVDAGTTVTIAVPLRVAT"
     misc_feature    complement(18136..18138)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18462..19199)
                     /locus_tag="BAY61_RS05705"
                     /old_locus_tag="BAY61_05665"
     CDS             complement(18462..19199)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005442906.1"
                     /locus_tag="BAY61_RS05705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05665"
                     /product="ABC transporter permease"
                     /protein_id="WP_091799377.1"
                     /transl_table=11
                     /translation="MNARILRVEIADELRGIVREPTALFFSIVMPVAFFALFVSLYGDQ
                     SSATVQRGTAMIATFGTFGVLTVVLLNPGTGIAADRGSGWLRAKRVSAVPISATLAAKV
                     IATMPYAVGVLIAMTATAAITGNLNGSVADLARVYAVLLIGAIPFALLGLAVGFQTSAN
                     ACVAILNAILFPAAILSGLWMPLEILPDFFADIAQFLPTYHLAQLALAQLTSAPAVGHL
                     LALLAATVVIAPLAALSYRRARP"
     gene            complement(19196..20098)
                     /locus_tag="BAY61_RS05710"
                     /old_locus_tag="BAY61_05670"
     CDS             complement(19196..20098)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020665950.1"
                     /locus_tag="BAY61_RS05710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05670"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_245865839.1"
                     /transl_table=11
                     /translation="MNTVLEVRDARHSYREQRALSGVDLDVQAGECVALLGPNGAGKTT
                     LVNLVIGLLRPQADTRVRLCGGDPAKASTRRKIGVVQQSLGFPTTLTVLELVTGAAVRA
                     GRSRAAAGPVLAELGLTELGKRRAAKLSGGQRQRVQLAMALVADPALLVLDEPTGGLDV
                     PSRRRLWSTLAERRARGTSILVTTHLVEESAEVADEVVVLDRGRAVAKDPPAELIAKLP
                     DRTVSARTALDLAVLRGLPGALSATLDGQRVTLATREPETLVRALLAADDALTDLRVEG
                     ASLEEAVEVVIGQTTGAAA"
     misc_feature    20670..20685
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.38"
                     /tool="antismash"
     misc_feature    20671..20685
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.53"
                     /tool="antismash"
     misc_feature    complement(20722..20737)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.76"
                     /tool="antismash"
     gene            complement(20820..21431)
                     /locus_tag="BAY61_RS05715"
                     /old_locus_tag="BAY61_05675"
     CDS             complement(20820..21431)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018745.4"
                     /locus_tag="BAY61_RS05715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BAY61_05675"
                     /product="DUF1345 domain-containing protein"
                     /protein_id="WP_091799383.1"
                     /transl_table=11
                     /translation="MPTAAVRAITGLAVGALTGTAIGFATNWQAGLLVGWMAGAVVFLL
                     WTWFIILPMDSGSTARHAVSEDPGRAWTDLLVVLSALASLGAVCMLLLTDGSKNIQAAF
                     SVGSVVLAWGAVHTIFTTRYARLYYTAPVGGIDFNESAAPTYSDFAYLAFTIGMTFQVS
                     DTDLTSKTMRATALRQSLLSYLLGTVVIATMVNLIAGLGR"
ORIGIN
        1 tgccatgaag ccgctccttc tcgtgttgtc ggtggccgcc cgtccgcgtg tgacggtcag
       61 gcgacgcggc tggtcgtctc ctgctcgccg tcgtcggcga ggtgaatgtc ctcgacggcg
      121 atgttgacct cgacgacctc aaggccggtc atctgctcga tggcggtgat gatgttggcc
      181 cgcacggtgc gggccagcgc gggaatgggc gtcccgtact cgacgaccac cctgaggtcg
      241 acagcggcct gcttgtcgcc gacctcgacc gaaacgccct gtgcggcgct ggaaccgccg
      301 ccgggaaccc gttcccgcaa cgcgccgaag gcgcgtgcgg ccccgctgcc gagtgcgtgc
      361 actcccggca cctcacgagc tgcgagcccc gcgatctgac gtaccacggt actggcgatc
      421 gtggtggttc cctgactcgt caacagcacg ctggtgcccg gttcgtgggc ttctcctgcc
      481 gtgcggtccg cgccggcctt cgcgggtgtg ctgctggtca tcgtgctggc tctcctcatc
      541 cgcagttgct gtaattgtgg ttttcgctct tgttctttcg ctgccgtggc acagcgccac
      601 ggccggttcc cgttttctct tgtgccggcc accgcgatgg tgcctgtggg aaccgcgtgt
      661 acccgcgaca ctagcggtgc gagccccgct ttccgctgaa gcgcgaccgc gtgctcgctc
      721 acctccagca tgccgggttt cgcggtggct gattcgatca tgctcccgtg ccgccgtcgc
      781 tcgccacgaa ccggtctcgc cgaccaccat caactccgca acgccatctg catgatcgga
      841 tcgctggtcg gctggggcga gccaccggag ggctccgccg tcagcccgag cgccgtggtg
      901 tcctccggca gatctccgac gacgggttgc gccgctccgg catccgtccc ggcgagtaca
      961 ccgagcgagt gtgcgccgga agggcccatc gcccacaact ggtacacgcg gtcttccggc
     1021 acggtcggca gccgttcgcc gaggaagacc gccttgccga gttccgccga cacgacgacg
     1081 gtcgccgccg tcccgtctcc cgcgctgtgc agcacacgga catcgctcgc atgcagtaca
     1141 gcggccatgt cggcccctcg ggttccggcc tgttcgatgc gctgctccgc ctgccgcagt
     1201 tcgttgtgct ggcgcagcgc gatgcctccg aagaccgcgg cgagcgcgat gccgacgaca
     1261 gcggcggcga cggccgcctt cgtcgcccat cctcgccacc gtgaggcggc gcggccggac
     1321 accctcggct gctcctcgga cggtggttcc tgacgagtgt gggcgacgtc gtagagcacc
     1381 cgtgctcgca gttgctcggg tggctcggcg gagacggcgg cgccgagctt cgccgcggtc
     1441 gcgcgcaatt cctcgacctc gctcgcacat tcgtcgcagt ccgcgagatg gtgctcgaac
     1501 tcggcgcgtt cccgcccggt gagcgcgttg acggcgtagg cgccggtgag ggtggggaag
     1561 tcgtggttca tgagcccacc cgcaagcagt cgcgaagccg gatcaggccg tcccgcagcc
     1621 gggtcttcac cgtggaaggc ggggaatcga gcagcgaagc ggcctcgcgg taggtgtatc
     1681 cgcggtagta ggtcagcagc accgattcgc gctgaaggtc ggtcagcgtc gccagacagc
     1741 gccgtacctg ccgctgctcg aacctcgcca gcaccgattc gctgacctcg tcgaacgagc
     1801 gctccgccga gcgggaaccc gctttcgtct cccgctcggt cgccgactgt tcggatctga
     1861 ctctgtcgac ggctcgccgg tgtgcgagcg tgagcaccca ggtcatcgca cttcccttgt
     1921 ccggccggta atgcgttgcc gtccgccaca cctgaaccag gatctcctgg gtgacctctt
     1981 ccgattgggc ggcattgcgc acgatccgct gcacgaggcc gaacaccggc ctcgcgatga
     2041 ggtcgtagag ctgttcgaac gcacgctcgt cacccctgcc gacctcgacg agcagagcct
     2101 gagggtcgga aggtggctga ccttgcgccg taccggcgac gggagcctca tcagccacca
     2161 gtgatcatct cctcggtgcg ggggtgcgcc tgcaccgccg ctgcattgtt catcgggata
     2221 ccggtttgtg caggccgaac tggcagacgt cgaggtagcc ggaccggaac ccggcctcgc
     2281 tgtaggcgag atagaactcc cacattcgcc gggggagttc gccgtcggtg cctggccggc
     2341 cgtctcctgc ccagtagacc ggccagttcg cgttcagtcg ctgccgccac tggcgcagtg
     2401 tctcggcgta tcccgaaccg aaggcacgcc gctcgacgag tgtcatgccg gtgttggccg
     2461 cgacgttgcg ctcgatcacc ttcaccgaag ggagctgtcc accggggaac acgtacttgt
     2521 ggatccacgt ctgggattca cgggtggcca gcaggcggtc gtgcggcatc gtgatcgctt
     2581 gcaccgcggc tttacctccc ggtagcagca accggtcgag ctgccggaag aacgtcggcc
     2641 agtactgtgc gccgacggct tcgatcatct cgacgctcac cacggcgtcg tagcggccat
     2701 gctcctcccg gtagtccctc agccggatat cgacgcggtc ggcgaggccc gcgcgggcga
     2761 tccgttcctc cgccagcttc cgctgctctg ccgacagcgt gagtgtggtg acgtgtgcgc
     2821 ccctgcctgc tgccacgacc gcgagtgaac cccagccggt tccgatctcc agcaacctgc
     2881 tgccctcccg cacccctgcg aggtcgagca ccgccgcgag cttgcggtcc tgggcctccg
     2941 cgagatcgcc accaggacag agcggcgcgc ccgagtaggt catggccggg tcgaggaacg
     3001 aggcgaagaa ggtgttggag aagtcgtagt gccgccggat gttctcgcgg gctccccgct
     3061 cggtgttgcg ctcgctcgcc ggccggttcg tgtcgacgaa tccgcggaac gcctgtaatg
     3121 gccggggaat gaggtcggcc atcttcgccg cgaacggggt gagcagttcg gcaggctcgg
     3181 ggctggtcca gtcacccgcg agatatgcct cgccgaaccc gatcttgccg tcgtggccca
     3241 gccggtggaa gaacgcggcc ggccggtgga cgcgcatcaa cggtgagccg gactcgccgg
     3301 tgccgagccg ctcgccaccg gccagcgcga tttgtacggg caacgagcga accgcgtgcc
     3361 ggaaggcgcg ctctgcgatc gcggccctga gcggcgcgtg cgggggaggg ccgagctgct
     3421 cccacggtgg accgtgatcc ggctcgcgtg gcggtacagc cagccgggtc tcggcatcga
     3481 tgacgctcat ctgttctcct cggctgcgtt tttcgtgtgg gcgacggagg gggcgccgcg
     3541 cgcccacagc gccacaccat gtgcgcggat gagcgccgaa acccgttgcg ggaccagtgg
     3601 gtgtcgcagc agcgtcgtgc cgatgttccg gatactcgct cgccgccggg tgccttccag
     3661 tgtcgcggtg agcagcggcc cttcttcgga gtgcagctcc actctcagat cgagccgttc
     3721 gccagggcag gggagccaca tccggtaggt gcccctgctg ggaaggaaag gtgacacgta
     3781 gaaccgtttg ctcgcctcgg cgaagccgtc ttctccaggg aagagcagat agcgctgtgc
     3841 ctcgccgtag gtgttgtgca cctcggccac gacacagcgc tggcggccgt cctcaccgaa
     3901 gcaccagtag acggtgagcg ggttgaacac gtggccgagc accctcgcat gcgcgagcat
     3961 gagcaccctg ccctcaccga tccggacacc gtgctcgtag agccaggcgc tgaggccgcg
     4021 ccggatcggc gcgcctcggc ggccgagatg atcgcgcgcg tcgaagcgag tgaacggccg
     4081 tagccaccac ggcagccgcg gtagctcgtc gatgtccacc agccacaggt agagccggtg
     4141 ccggaaaccg ccgccgacgt cgatgtgcct ggtgtggccg accgtcgcct cgtacaacgc
     4201 gggtgccgcg atcaccagcg tgctccgaac gattccgcgg cgcgcacccc cgaggcgcag
     4261 ccgtcctcgt gaaagcccca gccgtggtag gcgccggcga acgcggttct tcccgtattc
     4321 agcgcgggaa gcctcgtcga ggctgccacc gaatcggggg tgaacacggg atgccggtat
     4381 gccgtcctcg cgagcacggt ccgctcgtcg aacccggctg cgcccaggga caccacgtag
     4441 tcggcgggct cggccagccg tagcaggcgg ttcatgtcgt agctgaccac catccggtcc
     4501 gtgttggcag agcaacccgg cttcgcgtag ttccacgacg ccctcgcacc ccgcgccttc
     4561 ggcaacacgc cggcgtcggt gtgcaggacg gcctcgttgt cggagtagcc gaacgcgccc
     4621 agcgtgccgc tctcggccgg cgtcggggag tccagcagcc gcagcgcgtc gtcggcgtga
     4681 gtggcgagta ccactttgtc cgccgggtac acctcgtcgg ctacggttct gacctgcacg
     4741 ccgtcgtgcc cgcgcgacac cgctctcacc ggagtatcgg ttctcacgaa cggcaggttt
     4801 ttcgcgagca gatccacata gcggcgcgaa ccgccgacga cagtgcgcca ccgtggtgag
     4861 ccgcccacgc tcaacattcc atggttgcga aggaactcga acagatagcg tgccgggtag
     4921 tgaccgctga tccgaggtcc cgccgaccac acggcactca ccagcggtag ggcgaagtgc
     4981 tccgtgaagt aatgcgagta tcggcccctg gcgaggaatt ctccgatggt catgccggga
     5041 gcgggcgcgc ggggatcgtc gagcaaccgg ttggccgccc ggtgaaaggc tcgcacctgg
     5101 gcgagcagcc gcaggtaaac cggcttcgcg agattggccg gttgtgcgaa gaggccgccc
     5161 agcctcttcg cgcccgcata ttcgagaccg caccccgcac agctcacgct catcgacatc
     5221 tccgtgtcct gagttggcac tcccagctcg gagaagagcc gggtgagctg cgggtaggtg
     5281 cggtcgttgt ggacgatgaa gccgctgtcc acgccgatgg cggagccgtc gccggtcact
     5341 acctcgtggg tgtgcgcgtg tccgccgagc cggtcgtcgg cttcgaacaa caacaccctg
     5401 tgagtcttgc gaagcagata ggccgccgtc agtccggaca cccccgcgcc tatgacggcg
     5461 acggtgggtt tcgtggggtc gtgcgactgc atacccggcg ttcggagcgg accggttgcc
     5521 ggactgccca atcgaatgtg atggaagaca catttttcgg gtaggtgatg ggcggccgag
     5581 ccgagcggcg gctccgaaca acggacatgg gtctcatgtc cggactgtcc cggtgtgtgc
     5641 cacggttgga ggagtgccga tgagtgtcac tgacgtgctc ggcgcggtcg cgctcgcact
     5701 aggggccgcg agcgccgtcg tcgtggccgc cttcgtggtg gctctggtac ggcgtcgcta
     5761 cgacacgatc gacagctttt ggggtgcggg gttcgccgtc atcgcggtga cgggtttcct
     5821 cgccgaaccg cgtgggctgg gaagctcact ggtggtgacc gcgctgaccg tttgctgggg
     5881 aacgcggctg tcgtggcaca tccaccggcg caacgtggcc ggtggagaag accgcaggta
     5941 cacggagatg ctcggcaggg ccaagcggta cccgcgactg cgcatgttct gcaaggtgta
     6001 cctgacgcag ggtgccgtca tgtggttcgt ggccctcccc gtcgtgctgg cgcagcggca
     6061 ggcagacgag ctcggagcgc tggccttcgc gggcatcgcg gtgtgggcct tcggtttcgc
     6121 cttcgaggtc atcggtgacg agcagcttcg ccggttcaag gccgatcccg gcaacaaggg
     6181 ggcggtgttg cgccacgggc tgtggcgcta tacccggcat cccaactact tcggcgacgc
     6241 ttgtgtctgg tgggggatct acctcatcgc ggcgcagcac cttcccggcg tcgcgactgt
     6301 gctctccccg gtgctgatga cctggctgct ggcaaggggg agcggaaagc cgttgatgga
     6361 acggcatctc gcggcgagca agggtggcta cgccgactac gtgcgccgta ccagcggctt
     6421 tgtgccgttg ccgccgaagt tctagcgctt ctccgcggac acggcccgct cgatctgggt
     6481 cagcggaagc cgtcggtggg cgggttcgag gtagcggtcg ttgaactcgg tcgcgccgag
     6541 gtcctccgtc ttgtgccagc cgtactcggt gaggaaatcg gtaaccgtgt cgggggacat
     6601 cccgaatcgc cacaggtggc ttttggtgac gaactggcgg tgggcttccc gcgcgtcgta
     6661 caggttttgc ccgctgagga agtcgctccg aacgtaggtg aagcccagcc tgctgcccac
     6721 gggggcggtt ccgaggaagt cgaaggtgcg gcgcacgtcg cgttcggtca gatactgcgt
     6781 gacggcttcc cacaggaagt acgtcggccg atcggcccgg tagccgtagt cgccgagcac
     6841 ctcggcgagg ttctgcctct cgaagtcgac agggaccagc gttgtcgtct tcggcacgct
     6901 acagaacaac gcgtgcaggc gctggtattt ctctgtgatg ttgcggggca ggtcgacctc
     6961 gaaaaccggg atgtcggcga gcgcgggcag ccggtaggcg cggtcgtcga gccccgcgcc
     7021 gaggatgatg accgtctcac aaccagagga gacggcttcg gtcaccgcgt cgtcgaagta
     7081 ccttttgcgg cacagcatgc tggcccacag gccagggaat ttgtgctccg tcgcgcttct
     7141 gatgacctcg cgcagtttcg gccacctcgc cacggcggcc atcgctctcg ccgtgggtgg
     7201 gaggaaatga tgcgccagct cgtcctggac cagcggatgc tgctcgtact ggtccatcgc
     7261 gacgatactc atcggctcta ctgcggtttt ggcaggtcct gttgccatgg tcgaggttcg
     7321 ctttcctgaa cggggtgagt cttagcaggc gaaaccggca cggttcagag tgacaccccg
     7381 agccgcgaaa agagagatgg atgccctgag atgaccaatc cggcccagaa gcgggtgacg
     7441 gcgggccgtg gaggccggaa cggcagcggt gcgcatatgg cgtggatccc cggtcgatgt
     7501 ggtgggcagg gagcacacta acgccgtgtt cgcgccgccg cgcactgggc cgtcgaaatg
     7561 cccgttttcg cacgtgatgt ggtcgctcct cgccgggctt atggcgaccg agacggattg
     7621 gccaaatcca ctgtggatgc cgttcggccg cctctagact gaccacgctc ggcgcgtcgg
     7681 tcgacgctga cagtgacgga gtgtgcgtgt gaagttcgag ccgccttttc ccgactcctt
     7741 gcccgacacc ggcacgctcg gcatcatcgg cgcggccaac acctacgcga tcaggctgcg
     7801 agccttctac aattcgcggg cggtctggca tcgccgcttc taccggttca gcgggattct
     7861 ggtcatcgcc gcgggcgcgg ggctccccgt ggtcgccaac ctcgattacg gtggcaagga
     7921 actcgtcgtt tcactcatgg gaacgttggt ggctctgctg accgcgttgc acgcgttcta
     7981 ccgctgggac cagtcgtgga tgctgttgcg gcacaccgag atgcggctga cctcggccta
     8041 ctgggcatgg cgggcagcgt tacccgccac agtcagcgac tcaggcgccc ctgatcccac
     8101 cacggtgacg ttgaccaggg atttcttgct cgcgctctcg cagatcaggg accaggaagc
     8161 ggtctcgttc ttcgagaaac tcagcttccc cacggctacg gccaatcacg tcgacgtgcg
     8221 gtagtgcccg ggaaggtagc cggagaacag gaaattgtcg gcgaacctgc gggccagcaa
     8281 ttcctcctcc ggtgaatgag cggtgaaggc gatgaccgga atgccgcgac cgcgccagaa
     8341 cgacaccgcc ctgcttggca gctccgcaag ctcgtagttg atgaagtcgg gcctggttat
     8401 cgcgttgctc agcatcatgc gaccgagagt gcccaccagc tttcccgccg actggagact
     8461 tcccgatgct tgaccgacgg gcacatgcgg ggcgagtttg cgcagccgtc gcacggcgat
     8521 gggatcgaag gactgcactg ccgtctgacc ccggtaaccg cgcagccggt cggcaacggc
     8581 acgttccagc ttcgcgttgc ccgctttcca gcggcgcagg tccagcagga gtggcacggc
     8641 gccatcaacc agggacaaca catcgtcgag ggttggcacc ggcaggtcgg ccgggccgat
     8701 tcgcagcgca cgcacggcgg cgaggtcgag gtcggccacc ggtgcactac acgttcccgc
     8761 cacccgggag aagtctctgt catgtacgac gattggctcg tcgtcgctgg tgagctgcac
     8821 gtcgaactcg aaaggcgcgc caagctcgat cgctcgccgg aacgcgggca gagagttctc
     8881 cgggtgttcg acggcgtcgt agcagccgcg gtgagcaatc ggcgcacttg tcagccagca
     8941 gggaagcggc acgtgtcctc cctggctcgc cgtgaccgcc ggggtcgtcg ggaccacggt
     9001 gcccgcaacc ctaccgctgt ccgtgcgaac acgggcagga tgatccggaa atccacagtg
     9061 gacataagtc ggccgtcggc gttcctggag gacaggaagg tcctgccgcg tcctggcgat
     9121 tctcacgccg ggccgtcctg ccggatccgt caaccgcggg cggcaaccag cgtccggctc
     9181 ctgtgacgag cccagccgtc gccgaaccct tgccttccgt gtgtctcggc acgtaccagc
     9241 gatactcgcg ggaagctgac gtctgccatc gcaatgtccg atcaggacag acgactaccc
     9301 cgctgccgac agcgagctcc ggccagcgct catctgctat tcgggcacat cggccgcttc
     9361 tcgcccgtgt gtggcagggg ctattgctcg tggtcatctc cgtcttgcgc gcccggccgg
     9421 gccctcacct gcggctcatc cgcgctggga gatgtgcgac gcgtccggtc ggggggaacg
     9481 cgggggcctg tgtgcagcag cgggtcccat ccccgctgag cggggattct gctgatcggg
     9541 gcgcgcgcca actgccagcc ggaacccagt cgccggcgta tctgcttcgg caacgcgttc
     9601 aacctgctct tgtccatctg aacctcctgc tcggccgtgt cgctacggcc acctgaacgg
     9661 ggttgaccag tcacgacggg accaaactcg gaacaggtct cgccttgcgg accgctaccg
     9721 tgcggcccgg accgacagca cacggtagcc atttacggcc gtggtggccg gataccgcta
     9781 tccggccacc acagtcaacg cggcacccca atgcagggcc gcgtcgcctc aagcctcgat
     9841 cagcacagca ggaggctcag gtagctgatg atggtgtggt acgccggatc ggtcgtggtc
     9901 tcgtcggcgt ccatgccttg cagctcaagt accgattcca tggtgcgttc cctttctttc
     9961 cgtgttttcc ttccacccgc tcgaaaatga gccgggcggc tcaatggggc gatgacgcga
    10021 tcacgctgtc gtcgccaacc gtggggacag gagcgaggaa cgggagaacc ccgctgtggt
    10081 catcgagtgc cgtggatatc gagagcagta cgcccgcgct gccggtggcg acatccatgg
    10141 acaaccggag caatttgttg ccggggaaag cgatgccgtc atcaccatcg ccgtctggca
    10201 aagcaaacgg aatggcgtgc caggccagcc tggcaaggtg cgatgcgatg gcgtcctcgg
    10261 ctgtggggtc atgcccgtag cggcgagcag cggcgagtgt ggccagcaac ccaccacgac
    10321 cggccagcaa cccgcactgt aacgcggcct cggcccgaca ggccctcaac agcagcggga
    10381 gctgccgcac gctcgtccca tcgtcggacg tgtgcttcgc cagttccatc gccgccatgg
    10441 cgattcccgc gctaccggtt ccaaggaacg gcaacgtccg cttgacgccg tccctgacct
    10501 gcatcgagcc gtcacgggcc ggaacgcatt ccgcgaggtc gcggcttagc gcgcgttcgg
    10561 catgaacgag ccattcgccg tctccagtgg cctcgaagag tcgggtgaac agcaacgcgg
    10621 gccccgacca gccttcgacc agcccggcct tcgctttccg gcccggcggt gccgcgctct
    10681 ccagctcggc caccagccgt tcgccgagct cgcccgactc acctccaccg tcgccgagat
    10741 acagcagagt cagtccgata ccggcgagtc cgttggccag tccgtggtcg cgggttttcg
    10801 ctatggaccg acgtgcgtct gccagcaggg cattcgccgt gtcgtggtcg ccgaaaccat
    10861 ggagcacgta tgcgattccg gctgctccat ccaggaaccc gggtgcgagc gggcggtttc
    10921 tgtcgatcgc gtcccgtagc cagcggtcgt gttccgggct ccggccgagc ccctcgacgg
    10981 ccagtgcgtg cagaacccct gcggcgccgt ggccgaaacc gaggccgccg agccggaact
    11041 gctcgatgtc acctgggaag agccggtcgg gacgttccgg cgtcgcgctc gtcagtattg
    11101 cctgtgcgat cgacttcctc acaagattcc aatccggttc gggatcgtcg agcactgtga
    11161 ccggcgcggt agtccggtgg ccgatcgtgc ccctgccgac agcgcggccc tcgcgatcgc
    11221 ggtcgtcctt ctccctggtg ccgcggcgca gcgttgccag aatcgactcg ccatagccat
    11281 tgggcaaggg gaatctgtct tcgacgaacc tgacccattc cggcagtttc gccggcgcga
    11341 gttcgaacag cgctgagagc ggaaggaaga gccacaggcg cagtgccgcg agcgcgtagt
    11401 cgtccacctc gaaaccggtc cggtcagccg gggcccggaa tccaggcgcg cccagcgtcg
    11461 gccggcgtgc cggaccggga ggacccgcga gctcgaagtc gatcaaactc accgagtcgt
    11521 cgtccgtgac gagcacattg gccgggtgaa gatcgttgaa gaccaaccct cggaggtgga
    11581 tctcgctcac ggtttcgccg attctgtcgg cgatgccgag tgctcgccgc gtgtacgcgg
    11641 cgacgtcgct atcactggcg cggtagttgg tcagcggata gttggcgccg agccatgaat
    11701 gcagtggtac tcccggccgg tgttccatgg cgaggaaaag gtgctcccat acgggcgtca
    11761 gctcatacac cgccggtact cccggaacgt cggtgaggga ggtcagtgcc cggtgttccc
    11821 tgcgcagcct ggcgaccgcg tcaactttgt cgccgtcgag gccggcgtgc ggacgtgcct
    11881 ctttcagcac cacctggttg ccttcacggg cgtgttcagc gaggtaaacc ccgcctccgt
    11941 tggaaaagtg cagcggccgg ttgacgtggt aggcgaagtc gccggtgctc ttggcgcttc
    12001 gtgcggcgag atgcggggcg agaaactcag ggagttcgac ccagtctggc aacgcgaata
    12061 ccgggccacg gtgatcggga accagcgtgc cgtcttcacg cgcgatcccg agcacccggg
    12121 tgcccccgct gtcgatccaa cgttcggtga aaccgccata ccgaacgtac agcggcccat
    12181 cgccatacct gaggtcgctc agaatgtatg gccccgcttg gccgccgata cgctggtcca
    12241 gttcggtcac caacgtctcg aactcgcggt cgtcgcgcgg gtagatcgtg accagcttcc
    12301 cgctcgcctc gcgaggggcg tatttcgaat tccgtgccaa caacacggcc agatccgtca
    12361 gatgcttgaa ggtgacggct cgttcgacca ggcactcgta aactgtggtg agcacttgct
    12421 cggcgttgtc cagcgtcgcg gaaacgtgaa tcttccagcc ctgataaggc aacgacgctc
    12481 cgagtggatg cagaacccgc catgtcccgt gctgtcgctc cgcccagccc tcttcgggaa
    12541 gcggggtgaa ccgggcgaaa cgttcggctg ccgagccgcg ctgttcgtcg aagaacagcg
    12601 ggtccgccaa acagaactcc tcgtaccgat gctccaccgc cacgcctcct ctgactgtgc
    12661 cgcacggact gtgctcgatg tcgttggctg tggacaccgt ggtgaccaag accgtaagca
    12721 gacattgcca aaccggagcc cggcaaacgg gaacttgtcc atggcacctc aaccagtgac
    12781 atttcgcccg ctgagtgcga gcccgctggg ttcgctgagg cgaatgagcg gtattgggat
    12841 cggtgggctc ccagatgatg acgctcagcg acaggagatc gaacgagtga cgagattgcc
    12901 gacggtgatc ggacaccatt caggggaggc cgatcgcgat gaatctgaag cagagtccac
    12961 tacggactga actgtgttct ttcccagcgc gagttcgccg ggcgtgaacc ggttcccgct
    13021 tgcgcgcatg cgagcgttgt ccgcgcgtac gcgcgagtcg aaccgaggag tccggaccgt
    13081 gccgacggga atgcgggtat cgcggccacg gctcaccgcc gatgtccggc gcaatctggg
    13141 ttacgccggc ggctcggttg tttacctgtg tgcacattgg agctacgagc ggagggtcac
    13201 cggtgtacga ggcgttctgg ctcgcctggc cgccaaatcg tgatgtcgag actgtcgtcg
    13261 ccggtcacca agcttgaggc tccgatgaga tccgccgcgt acaggtgctc gaactcctgg
    13321 ccacgaagat caaaaccggt ctcctcgaac atcgcttccg cgaaccgcgc atgtacctct
    13381 ttgtcttgca cgtcgcgcac gcggccccac agcttcgcgt caccttcgtt cggctcggtc
    13441 tcgaccgtcg ccgtgtgcaa gcagaaacgc gggtcgcgac cgaggtcgtg gaacttggtg
    13501 gtgttgggca taccgacgag ccacagttca tcctcgaaga agcgaggctc gatggggctg
    13561 atgcgaggaa atccatcggc tcgaagggtt gccaacatac acaggttctt tgtcgcggcg
    13621 tggcgacgcg tgaaaacctc ggcgatcacc ggagctgaga tgctgaactc tttccacgtg
    13681 gtcatcagcc aaaggtacgg cagattacgg gcatgagggt tcaaggtgat agagccccat
    13741 cgggctcaca tcaccggaaa atcagtttcc gcgaccgaaa ccgccgtcac cgtcgaacgg
    13801 gttctgctgt tgtggggtga ttgtggtctg ctgtgtgtct ttcgcgcttt cgagagccac
    13861 gttgaccgtc tcggtcgaac catcggcatg cttgaccacg acgggaacct cttcgcccgg
    13921 agtgtgtttg agcacctgcg ccatcaaatc ggcgtacgag ctgatcaacg tgtcgccgag
    13981 tttcgtgatg acgtctcctt gtcgaattcc ggccttctcg gcggcgcttc caggttgtac
    14041 cgaggcaagt tgtgcccctt cagccgtcga atctccctgg gggttcacgc ttccgctgac
    14101 tcccagcacc ggcttgttcg cttcgccgtt ctgcatcagt tcgttggcga tccgcttcgc
    14161 ggtgtcgatg ggaattgaga agccgaggcc atatgcctgt aggccgccgt tactgctttg
    14221 accaggctca acggccgagt ttacgccgac gacctggccg tccaggttca cgagtggtcc
    14281 ccctgaatta cccgggttga tgggcgcgtc ggtctgcaag ccgttgtata cgacaagttc
    14341 gccgttgtcg tctcccgctg tcacggtacg actgagcgca ctgacaattc ccgaggtaac
    14401 ggtgttcgag agttcttcgg ggctaccaat ggccgccacc tgctggccga ccttcagacc
    14461 gctggactca ccaagcgtcg cgggcgtcaa cccgtcggcg tcgtccagct tgatgacggc
    14521 gaggtcgtac gaaggcgcgg taccggtgac agaagcggag tatttctttc cgtccggtgc
    14581 tgtcacctgg atcttgccgt tttccgatgc tccggccacg acatgattgt tggtgagtac
    14641 gtagccatcc tcagagagga tgatgcccgt gcctgtcgcc gtgccctggc ctgtggggac
    14701 cttgatgtcc acggttgatt tcatcgccac ttcggcggcg tactcgaccg aaccaggttt
    14761 ggagctgacg ttgctggctg atgccggctg ggacgtcagt acgggtacgg cggagtccgt
    14821 cgacaggagc gcgttgccgc ccagcgcggc gccaccgccg acaagaccgg cgatgatcgc
    14881 ggtggcgatg atcgataccg gtactctgcg tttcggtttg gcgagcgccg tcggaaccga
    14941 gccggcgaag ccggtagcag agtggggtgg ctgctgctgg gcggccaagc cccatgcggg
    15001 tgtcgcggct tcttgtgtgg cctcggcaac gtcgtccgtc cgttgttgct gtgcgcttgg
    15061 cgagtccacg aggggtgcga tcgattcctg ggggctcggt ttgtgcgcct tcggcgcgcc
    15121 cggctgccac gaccccgcat ccccctgctc ggctggggtt tgctgaggtc cggactggtc
    15181 tggttgcggc tggtgctggt gaggggagtt ttcggtcacg agcccacgat gcgtcttgaa
    15241 cctgagaaac ggcgcagaaa ggccttaaaa gttgcgtggc tctgttggcg atcgtttcgt
    15301 gcggagtcgg tcagcccggc gactgccgcc gccgggccac gtctgtttcg cagtaacgcg
    15361 ggatcttcgg cgggttgtcg gcatggcgaa cggggtgcct gccgggccaa cgtcggggga
    15421 aggcccggca ggcaggtcga tcagcggatg ttgctggtgt gccccagtga gtagcggcct
    15481 ggttgtggca tataagtcag cccgtgtggt cctgagccga cgggtatgcg ggcgagcagg
    15541 ttcccgttgt cggtgtcgag cacgtagacc tcgttgtgat gccggccgga cagccacagt
    15601 tgctttccgt cagcggacac cgaccccatg tcagggctgc cgccaccggg gatgtgccat
    15661 ttgtcgatgg gtttgttcgt gccggtgtcg agtatcgtca cgctgccttc gccgcggttg
    15721 gtgatgaagg cacgtttgga gtcgcgcgag aagtacacgc catgtgctcc ctgcccggta
    15781 ggcacgaaac cgacctgttt ggtcgcgtcg ccgtcgaaca ggtagatccc gttggcatgc
    15841 atgtcggcga cgtagaaggt gcttccgtca ggggacaacc tgctgtcctg aggcatgcca
    15901 tgcggcgttt gatcgagttc gaacgtccgg acgtgtttct tggcttcgac gtcgaggacg
    15961 atcatccggt tggcgaactc gcaggtaacg agcgcgagct tgccgtcctt ggtgaagtcc
    16021 atgtggttga tgcccgcaca ctcgtcgatg tgaagcgatt cctgcttccg ccaggtgtgc
    16081 ggttcgtaga agtcgagacg tttataggct tcggctacga caatcgcgga cttcccatcc
    16141 ggggtgaagt acaggttgta cgggtcctgt acgtgaatga gttcgcctgc tttgccggtc
    16201 ttcgggtcga tcggcgtcag cgtgccgccc ggcacctcgt ccgccgtgac atacagcgtc
    16261 ttgaagtcat acgagggaac gacgtgttgc ggctccagac cgccggggat cgtgtcgatg
    16321 actttgaagg tcgagggatc gatgatcgag acggtgttgc tgacactgtt gggcacgtac
    16381 acgcggttga gtacgccctc catggccggc gaaaagtttc caggccgtgt tgccgcatat
    16441 acatcccgtt cgctgtcctc ttcggccttc gcttcgggtg gttgagcacc tgcctcctgc
    16501 acggccggct gctcgaccgc gtcggcaggc ggggcattct cgaccgaatc ctgactaccg
    16561 cagccggtca gcagcaggct cgtggcgaca aaagcgaccg ccactgaggt tccagtgatt
    16621 cgcatgacca gcgacgttac aagtggaagg ccgtggcaac ccgatgaaac cgctgtggca
    16681 acgggtgtca cggtcaactg ctacccggat gggcgacccc tgactgaggc cgttctgtca
    16741 gtcattccgc gaacctgtcg gcggactcac ttcacaacca gccgcgttcg cttgcggcct
    16801 tggccgcttc ggtccggtta cgcgcgccca gttttgccat cgcgctggaa agatagttgc
    16861 gcacggttcc ttcggcgagg tgcagacggg ccgcgatctc ggcattcgcc gcgccgtcgg
    16921 cgacctctcg caggagttgg cgttctctgt cggtcagcgg gtcaggccgg ccccaggccg
    16981 cgacagccag ctcgctcgcg attacttgtt cccccgcgtg aacgcgccgg agcgcgacca
    17041 taagttcgcc gatgggcgcg tccttgagta catagccggc gacgctggcg tcgagcgcgc
    17101 gccgaaggta cccggcccgg gcgaacgtcg tgacgatcag gatgcgcacg gggtgcttcc
    17161 tccgagccag ttccaccgcg acatcaaggc cggagccgtg cggcatctcg atgtcggtga
    17221 caagcacatc cggctggtgt tcctcgaccg cggcgagtgt ctcctctccc gttgcggttg
    17281 ccgccaccac ggtgacgtcc ggttgtagat ccagtaagga cacgaacgca ctgcgtacca
    17341 tcgcctgatc ttcggcaagt acgacccgga tcggcggatt cgtgctcacg tggccaccct
    17401 gagcggaacg gcgatggtca ccgtggtgcc cgcgtcgacg attttctcca ccctgccacc
    17461 cagcgcgctg atccgttctc gcatgccagt caggccgttg ccttccggcg cggagccgtc
    17521 gccgacgccg tcgtcggcga tgacgagaca caggtcgtct ccgacgactc cgacatcgat
    17581 atgacaggtc gttgcccgcg cgtgccttgc cacgttggtg accgcttctc tcagcgcgag
    17641 cgccagttcg tgttcggtgg aacccacgat tgtcagtgtc gcatcacgtc gaactctcgt
    17701 cgtgatgcca accgtggcca gcgtttcctg cgcggactcc agttcggcgt cgagtcccgc
    17761 gtttcgccag ccggcaagag tcgccctgat ctcggacagc gcggtacggg cggtgtcctc
    17821 gatgtcggtg agctcgcttc cggcccggga gttgctccgg tcgagtagtt cattggccaa
    17881 ttgagcccgc acgatgattg ccgtgaggga gtggccgagc aggtcgtgga gatctctcgc
    17941 gatgcgttcg cgttccgcga tcgtcgccag gtgctcgacg cgggcgttcc gcattcgcgt
    18001 ctcgacctct gctcgttcgc gttctgacca gcttatctgg agggaaccga tgacccacag
    18061 gtaaatcagc gaggggatga gcccgtagag ccgccatggc atcggaacga acgacagcac
    18121 tgaggtcaga ctgagtaagg ccgagagtcc gatgaaccag cgcagagcgc tgcgccgaga
    18181 ctccgagaat ccagcgaatg ccgccgcgta cacgaacaag atcgccgcac cagcgttgaa
    18241 cggtgtggtg agtgcggcga ggaccgtagt cggtacggtg cccgtccagc gggctcttgc
    18301 cggccagcgc cacgatgcca cgtacatggg caggaacaca acgacgatgc ccgcgaccag
    18361 cgcccaatcc gccccgccgg agtcgcgatc gaagatcggc ccccacagca gattgaccag
    18421 atagatgagg tggatccatc tggagagccg gcctggaggt ttcatggtcg ggcacgacga
    18481 taggacaaag ctgccagcgg agctatgacg acggtcgcag ccagcagagc cagtaggtgt
    18541 ccgaccgctg gagccgaggt caactgagcg agcgcgagtt gcgcgagatg gtaggtcggc
    18601 aggaactggg cgatgtcggc gaagaagtcc ggcagaatct ccagcggcat ccacaggccc
    18661 gacaggatcg cggcagggaa caggatcgcg ttgagaatcg cgacgcaggc gttggcgctg
    18721 gtctgaaagc cgacagcgag gccgagcagc gcgaacggga tggcgccgat gagcagcacc
    18781 gcgtataccc gtgcgaggtc ggcgaccgaa ccattcaggt tgccggtgat tgccgccgtc
    18841 gcggtcatcg cgatcagcac gcccaccgcg tacggcatcg tggcgatgac cttagcggcc
    18901 agtgtggcgc tgatcgggac ggcggacact cgcttcgccc gcagccatcc cgagccgcgg
    18961 tcggccgcga taccggtacc cggattgagc agcacgaccg tcagcacacc gaatgtgccg
    19021 aacgtcgcga tcatggcggt acctcgctgg accgttgccg aggactgatc gccgtagagg
    19081 gaaacgaaca aggcgaagaa ggcaacgggc atgacgatgg agaagaacag cgccgtgggt
    19141 tcgcgcacga tgccgcgtag ttcgtcggcg atctccacgc ggagtatgcg tgcgttcatg
    19201 cggcggctcc cgtggtctgt ccgatcacga cttcgacggc ttcttcgaga ctggcacctt
    19261 cgacccgcag atcggtgagt gcgtcgtcgg cggcgagtag tgctctcacc agagtctctg
    19321 gctcccgggt ggccaatgtg acccgttgcc cgtcgagtgt cgccgacaac gcccccggga
    19381 ggccgcgcag tacggcaaga tccagcgcgg tgcgcgcact gacggtccgg tcagggagct
    19441 tggcgatcag ttcggcaggc gggtctttcg cgacagccct gccgcgatca agaacgacga
    19501 cttcgtccgc gacctccgcg gactcctcga cgagatgggt ggtcaccaga atggatgtgc
    19561 ctctagcccg gcgttcggcc agtgtgctcc atagtcgtcg ccgactcggg acgtcgagac
    19621 cccccgtggg ttcgtcaagc acgagcaagg ctggatcggc gaccaacgcc atcgcgagct
    19681 gaacccgttg acgttgcccg ccggacagct tggccgccct gcgcttgccg agttcggtga
    19741 ggcccagttc ggcgagaacg ggtccggccg cggcacggct acggccggct cggacagcgg
    19801 ctcccgtgac gagttccaac accgtcagcg tggtcggaaa tcccagggat tgttgcacga
    19861 cgccgatctt tcgtctcgtc gaggccttgg cgggatcacc accgcagagc cggacccgtg
    19921 tgtcggcctg cggccggagc aagccgatga cgagattcac caacgtcgtc tttcccgccc
    19981 cgttcgggcc gaggagggcg acacattctc cggcctgaac gtcgaggtcg acgccggaaa
    20041 gtgcccgctg ctcccggtag ctgtgccgag cgtcgcggac ttccaatacc gtattcacct
    20101 gatccatgct ggcttgacgg agcctctgga tgtagtgcgg cgatgtcacc gatgcgtgat
    20161 gacaaatgtc agctgccgcg ggcatctcgt tcgcgccatg tgaaagttgt ggcgctggta
    20221 ccggtgtcgg gaagcgcgtc cggtaccagc gccgggaccc gcgacatggg cgggccctgg
    20281 caacccggca cagtggactg tcggcgtcgc ccgtcttggc ggggcgcgac gagcgttgcg
    20341 ccgggcgggt tgtaaggccg gaccggtcgg ccgtcactgt gtagttgtca atgagcgcgt
    20401 cgctgttcgt cgcgaggtca cggctggtgg ctggggtgaa tcacgtgagt gcgggaaatg
    20461 cgtgatctgt gacgggtggt ggttcgccac gtggttcaca gggtggcaaa ggagaagcgc
    20521 cgttggctag atgtgttcta gatgatgtgg ctgagtgggt tctggtgtcg aggggataat
    20581 gtcaaggtgg tgtcatccgt attctgacga gtgtcgtcga catgtgtgcg gtattgtttc
    20641 ttgtgtgcct tcggttcatg tttcctcctt ggaatgtgtg ttcaactatt actgagggcc
    20701 gtctggcgtg tcaaacaatt tgggaaaatg cagtgaagtc tccgttcgcg acaatcatcg
    20761 tggtcgcgat gcttgagtga agcggtattg aactgggccg gagtgctgat ggcgaggcgt
    20821 tacctgccga gacccgcgat gaggttgacc atcgtggcga tgacgaccgt gccgagcaga
    20881 taggagagca gtgattgtct cagtgccgtg gctcgcatgg ttttcgaggt cagatcggta
    20941 tccgagacct ggaaggtcat accgatcgtg aaggcgaggt aggcgaagtc cgagtacgtc
    21001 ggagcggctg actcgttgaa gtcgattcca ccgaccggcg ccgtgtagta caggcgcgcg
    21061 tagcgcgttg tgaagatcgt atggacggcg ccccatgcca gcacgacact gccgacggag
    21121 aaagcggctt ggatgttttt gctgccgtcc gtcagtagca gcatgcagac cgcgccgagg
    21181 ctcgcgagcg cggaaagtac taccagtagg tctgtccagg ctctgccggg gtcttcgctg
    21241 accgcgtggc gggcggtcga gccggagtcc atcgggagga tgatgaacca cgtccagagt
    21301 aggaacacga ccgcgccggc catccagccg acgaggaggc ccgcctgcca gttggtggcg
    21361 aagccgatgg ccgtccctgt caacgctccg acggcgagcc cggtgatcgc ccgcactgcc
    21421 gctgttggca tgcggtcgtt ttcttgtgtg tcctttggcg ggtcaggcct gttggtttct
    21481 tcggctgaca tggggagaac ctaccgaagg gctggtgaat aacggggaga ctatgcccct
    21541 gtcgggcgac cttgggtgtc attgtcgggg aaataggtat agtgggttcc ggtggttctg
    21601 gggtgggccg tgggtgactg tgaagtcgta tcgacgtggt tgtgaatgtc gttcgggcag
    21661 tggcgacaaa cgatccttgt tttcagggaa tcttgtcctg ctgggttgct tactgtttat
    21721 ttgcctgagc cgaggagttg gttttagttg cattagcgat cgtggttgtg agattgctga
    21781 atctcgtgta ttcggaaggt ggtgctgaat tcaaagattg aatgattagt gtgcggttgt
    21841 cagagacgag ggcgctgccg ttgccgggca gttcgcacga tggctcgtac gggcggtctc
    21901 gtggtcgcgc tattggtgtg ggtcgtcgat ctcgcgggag acgatggcgg tgttcgacgc
    21961 agtctgaact ctggagatgc tgcgacgccg gagcgcggtc cggagcgcga cggcggagtg
    22021 cggtggtgga gcgccgtgtt tggtttggag tgcgccggat cagtggctgt ttcggccctg
    22081 gccggggcct gtgtccggtc aggtctctgg taggtggata ccgggaacgg cgacgtgacg
    22141 ggccgagtgc cggatccttc acttggctac gtggcccggt tgtgagtgcc gtcgaccagg
    22201 ctcggcgtgg ctccgaccgg cgggatggtc tgaccagggc tgctgcggct ggagtcaccc
    22261 gggtgaggtg tggctagggc tgccaggcgc ggtgtgcccg gcacccggcc gggttggtgg
    22321 ctggagccca ccgggctcgt gcgatggaag gcgggctgag tcaggtgcgt cggacggaag
    22381 gagggccgcg tcaggtgcgt tggacggaag gagggccgag tcaggcgcgt gaagaatcgg
    22441 tggagtgatg cgacggggga gcggccggag agagccgagt caggaggtgg tttgcgcggt
    22501 cggtgtgttg cgggcggcca ggtaggcgtc gacggtgtgg agtttgtgct gccgggttgc
    22561 ccattcgatc tccgcttcgg gtgcgtccga acggatcagg gtgagcaact cgtcgtgttc
    22621 ccgaaccgac gcctcggttc gtgagggcat gaaggtgaag ctggagcggc ggacgaacga
    22681 catgcgctgc cactcct
//
