LOCUS       NZ_CP018741            20168 bp    DNA     circular CON 03-MAY-2024
DEFINITION  Bacillus cereus strain FORC_047 plasmid pFORC47_1, complete
            sequence.
ACCESSION   NZ_CP018741
VERSION     NZ_CP018741.1
KEYWORDS    RefSeq.
SOURCE      Bacillus cereus
  ORGANISM  Bacillus cereus
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 257708)
  AUTHORS   Lee,J.-H., Kim,Y.-T., Kim,H., Ku,H.-J., Kim,H., Choi,S.-H. and
            Ryu,S.
  CONSRTM   Food-borne Pathogen Omics Research Center
  TITLE     Complete genome sequence of Bacillus cereus pFORC47_1
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 257708)
  AUTHORS   Lee,J.-H., Kim,Y.-T., Kim,H., Ku,H.-J., Kim,H., Choi,S.-H. and
            Ryu,S.
  CONSRTM   Food-borne Pathogen Omics Research Center
  TITLE     Direct Submission
  JOURNAL   Submitted (13-DEC-2016) Food Science and Biotechnology, Kyung Hee
            University, 1732, Deogyeong-daero, Giheung-gu, Yongin, Gyeonggi
            17104, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: PacBio SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 169
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002220285.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:13:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,922
            CDSs (total)                      :: 5,768
            Genes (coding)                    :: 5,607
            CDSs (with protein)               :: 5,607
            Genes (RNA)                       :: 154
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 73 of 161
            Pseudo Genes (incomplete)         :: 89 of 161
            Pseudo Genes (internal stop)      :: 42 of 161
            Pseudo Genes (multiple problems)  :: 36 of 161
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:30:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 138353
            Orig. end                         :: 158521
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP018741.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20168
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="2"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..20168
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20168
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10168](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10168
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     misc_feature    complement(795..810)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.06"
                     /tool="antismash"
     misc_feature    1023..1036
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.92"
                     /tool="antismash"
     misc_feature    1197..1211
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 19.87"
                     /tool="antismash"
     misc_feature    complement(1233..1245)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.92"
                     /tool="antismash"
     misc_feature    complement(1412..1428)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.59"
                     /tool="antismash"
     misc_feature    1435..1448
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: weak, score: 15.72"
                     /tool="antismash"
     misc_feature    complement(1528..1541)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.55"
                     /tool="antismash"
     misc_feature    1607..1620
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            2105..2233
                     /db_xref="GeneID:72452256"
                     /locus_tag="FORC47_RS28975"
     CDS             2105..2233
                     /codon_start=1
                     /db_xref="GeneID:72452256"
                     /inference="COORDINATES: protein motif:HMM:NF020945.4"
                     /locus_tag="FORC47_RS28975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="WP_245913026.1"
                     /transl_table=11
                     /translation="MKKEELISLVKQYGFTQETVICYSRELDLLLYDLMKFNRNNK"
     gene            complement(2634..>2807)
                     /db_xref="GeneID:72452257"
                     /locus_tag="FORC47_RS28980"
                     /pseudo=""
     CDS             complement(2634..>2807)
                     /codon_start=1
                     /db_xref="GeneID:72452257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016096850.1"
                     /locus_tag="FORC47_RS28980"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="zinc ribbon domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="VVKINKWFPSTKACSSFGSVKNITLSERVYSCI"
     gene            <2796..3326
                     /db_xref="GeneID:72452258"
                     /locus_tag="FORC47_RS28985"
                     /old_locus_tag="FORC47_p148"
                     /pseudo=""
     CDS             <2796..3326
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:72452258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284904.1"
                     /locus_tag="FORC47_RS28985"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_p148"
                     /product="amino acid permease"
                     /pseudo=""
                     /transl_table=11
                     /translation="YFHNLLNGFGIEIPKSLLTIPTQGGIVNLPAVIITLLLTWLLSKG
                     AKESKRVNNAMVLIKIGIVVLFISVGIFYVKPENWIPFAPYGISGIFAGGAAVFFAMVG
                     VSFIILRKTHPNLKRGFMVLLVPSLPIILITCCLFLMVNLPLKTWVYFGIWLFIGGIVY
                     FMYSKRHSQLNKL"
     misc_feature    complement(3409..3422)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.03"
                     /tool="antismash"
     gene            3960..6563
                     /db_xref="GeneID:72452259"
                     /locus_tag="FORC47_RS28990"
                     /old_locus_tag="FORC47_p149"
                     /pseudo=""
     CDS             3960..6563
                     /codon_start=1
                     /db_xref="GeneID:72452259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527246.1"
                     /locus_tag="FORC47_RS28990"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_p149"
                     /product="putative mucin/carbohydrate-binding
                     domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGNKSKHKTKRILAATATLTMLASGMVSSSDVFAEETQQQKKLST
                     SLQGEKSVKSENRTYTVPGKGDVEVLKQQERKSWTFSPYEPTGLYANPNEQITINVEGT
                     QNIDAYIGTRSYDAAWNEDSKIKSFTLKPGINTIQSPNGGMIYFYNKQQGGTIRTTVTT
                     GGTTTPFFELGKHTKQDLINMLDQYPNAHAVELKGERVLITASPARVKKYLLGSNTDPV
                     QLLKKIDEATRIQDKVAGLSEEQVDKHYLHYVEDNHSQGYYMYAFPQRTAYVGDAIQYV
                     LDINKFIKEGWGPWHETGHLRQQWPWTFYNMTEVQNNIYSLSVEKAFNQPSNLEKSGIY
                     PKAFQYLEQTNKNYDEISDAFVKLVMLWQLQLAYGEDFYPKLHQLYRDMPSSELPQTDE
                     NKKQLFMISASKVAKQNLIPFFEKWGLRPNNDTIQKVAALGYPILTAEIWKGTDSNPIK
                     PDIPNSSSILEGKQFAWSLKGIGDFEFAKVNLNKSTEEMQIDLKAGVPHNYFDSTYASI
                     KVQNASGKVVYNKDIYGNKQQNAESQKVSVKVGDYIELTHQEGVHRATLTNADNSKQES
                     FGKKAIYEVTKEGLKKVEKMPEATILDGNQFAWSLKGICDFEFAKINFNKSTEEMQVDL
                     KAGVPHNYFDSTYASIKVQNASGKVVYNKDIYGNKQQNAESQKVSVKAGDYIELTHQEG
                     VHRATLTNVDNSKQESFGKKAMYEVTKEGLKKVEKMPETTVLDGN"
     gene            6668..9403
                     /db_xref="GeneID:72452260"
                     /locus_tag="FORC47_RS29000"
                     /old_locus_tag="FORC47_p151"
     CDS             6668..9403
                     /codon_start=1
                     /db_xref="GeneID:72452260"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002169689.1"
                     /locus_tag="FORC47_RS29000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_p151"
                     /product="putative mucin/carbohydrate-binding
                     domain-containing protein"
                     /protein_id="WP_089172243.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 3.3e-17, bitscore:
                     56.5, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIFKGFLIASIAMTTFLGTDQILPDDSIHNKVYAESYNATNKET
                     DSNKRDSQEGQLIVKFKNEMDLPYEDGIEKRIKNGNYDNNLKKLFSENTELTLNRLFSS
                     VNPIEIEKLSLHSKSFANQSAENLLNYYIVQAPNNIEIELLLKKFETSPLVEEAYIQEK
                     QILTPPEVQLPGLSVNPYDDPRFKNQGYLEAAPKGINASHAWSIKGGDGKGTTFVDMEY
                     GWLLNHEDLVNQNIKLMSGQNISQHRAHGTSVLGIVSSEDNQIGNIGIAPKANVKVISQ
                     IRDNGIYNTADAILSAVHNLQAGDILLLEAQASYDGYGDKYLPVEVHPDIFDAIRVGAD
                     KGIIIIEAGANGSNDLDNFKDRNGKKILNRNSPDFKDSGAIMVGAGSSTVPHKRLWFSN
                     YGSRLDVYGWGENVDTTSANPSQNTTNLYTSTFSGTSSASPIIAGAATSIQGIAKEHRG
                     SPYTPAELRNILSNPNTGTKSQDPWNDRIGVLPDLKSILDNLGFNSDIPSSSSILEGKQ
                     FAWSLKGIGDFEFAKVNLNKSTEEMQIDLKAGVPHNYFDSTYASIKVQNTSGKVVYNKE
                     IYGNKQQNAESQKVSVKVGDYIELTHLEGVHRATLTNVDNSKQESFGKKAIYEVTKEGL
                     KKVEKMPEATILDGNQFAWSLKGISDFEFAKINFNKSTEEMQVDLKSGIPHHYFNETYA
                     SIKVQNASGKVVYNKDIYGNKQQNAESQKVSVKVGDYIELTHLEGVHRAVLTNVDNSKQ
                     ESFGKKAMYEVTKEGLKKVEKMPETTVLDGNQFAWSLKGYNDREIAKVEYNKATEKMQI
                     KLEAGIPHSYFTSTYASIKVQNSSGNILYNKEIVGNRQQAAENQTVPVKVGDYIEFTHI
                     EGEAQKEKIRATLTNLENSKQEFVGKKKTYQVTPTGLLIK"
     misc_feature    9580..9595
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.55"
                     /tool="antismash"
     gene            10001..10168
                     /db_xref="GeneID:72452261"
                     /gene="scfA"
                     /locus_tag="FORC47_RS29005"
                     /old_locus_tag="FORC47_p152"
     CDS             10001..10168
                     /codon_start=1
                     /db_xref="GeneID:72452261"
                     /gene="scfA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821353.1"
                     /locus_tag="FORC47_RS29005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_p152"
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="WP_089172244.1"
                     /sec_met_domain="TIGR03973 (E-value: 2.9e-22, bitscore:
                     72.2, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 2.8e-22, bitscore: 72.3,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIITLSTCKLQDTIKHGGCGACQTSCQSACKTSCGVANQKCEN
                     TMEKEPSIFY"
     gene            <10141..>10584
                     /db_xref="GeneID:72452262"
                     /locus_tag="FORC47_RS29010"
                     /old_locus_tag="FORC47_p153"
                     /pseudo=""
     CDS             10141..>10584
                     /codon_start=1
                     /db_xref="GeneID:72452262"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513581.1"
                     /locus_tag="FORC47_RS29010"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="FORC47_p153"
                     /product="4Fe-4S cluster-binding domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="PTHR43273 (E-value: 4.3e-38, bitscore:
                     125.0, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.5e-08, bitscore: 28.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRAIDFLLENSGNHRNLDVDFFGGEPLMAWKTFKQIVAYARNKE
                     KEYKKTFRFTFTTNGMLLNDEITDFLNQEMHNVVLSLDGRKKVHDYLRKTVNGKGSYNH
                     IVPKFQEFVEKRGDKEYYVRGTYTHNNVDFTNDIFHIADLGFNE"
     gene            10738..11136
                     /db_xref="GeneID:72452263"
                     /gene="tnpA"
                     /locus_tag="FORC47_RS29020"
                     /old_locus_tag="FORC47_p154"
     CDS             10738..11136
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:72452263"
                     /gene="tnpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762755.1"
                     /locus_tag="FORC47_RS29020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_p154"
                     /product="IS200/IS605-like element ISBth16 family
                     transposase"
                     /protein_id="WP_000762752.1"
                     /transl_table=11
                     /translation="MKLDSNNHSVFLLYYHLVLVVKYRRNVFDDDMSDYAKDMFVRLSE
                     NYNITLVEWNHDVDHVHILFKAHPNTEMTKFINAYKSASSRLIKRDFPQVKKKLWKEMF
                     WSRSFCLLTTGGSPIDVVKTYIENQSEK"
     gene            11148..12260
                     /db_xref="GeneID:72452264"
                     /locus_tag="FORC47_RS29025"
                     /old_locus_tag="FORC47_p155"
                     /pseudo=""
     CDS             11148..12260
                     /codon_start=1
                     /db_xref="GeneID:72452264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016096850.1"
                     /locus_tag="FORC47_RS29025"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_p155"
                     /product="RNA-guided endonuclease TnpB family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTKQNKAYKFRLYPTED"
     gene            <12402..12965
                     /db_xref="GeneID:72452265"
                     /locus_tag="FORC47_RS29030"
                     /old_locus_tag="FORC47_p156"
                     /pseudo=""
     CDS             <12402..12965
                     /codon_start=1
                     /db_xref="GeneID:72452265"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513581.1"
                     /locus_tag="FORC47_RS29030"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_p156"
                     /product="SPASM domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="TIGR04085 (E-value: 2.6e-18, bitscore:
                     60.1, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="KISMEPVICNPREPYALGEKDLLEIYNQYEILSKEMLNREEKGDA
                     FTFYHYMLDLSEGPCVQKRISGCGSGTEYLAITPWGEIFPCHQFVGEEEYSMGNIWDGI
                     TKAEIESQFKGNNCYSKPECQVCWAQLYCSGGCPANTIHATCSLKGTHEFSCKIFRKRI
                     ECSMMVKVAQSIRAMKKEEQAIVQ"
     gene            complement(13111..13506)
                     /db_xref="GeneID:72452266"
                     /locus_tag="FORC47_RS29035"
                     /old_locus_tag="FORC47_p157"
     CDS             complement(13111..13506)
                     /codon_start=1
                     /db_xref="GeneID:72452266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016119385.1"
                     /locus_tag="FORC47_RS29035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_p157"
                     /product="DUF3221 domain-containing protein"
                     /protein_id="WP_089172245.1"
                     /transl_table=11
                     /translation="MLSKKQKLVTVVTTLTLGCGLAFGLTPTSADSISNPTPIKEEKVR
                     IQIPFTGYVISADDNYLVVANTNTKEEALSYQNNWWELASQNKILRVPITSKDNYSVGE
                     KLNIFSVGWTHSIPPIAVMPVIEKIIE"
     misc_feature    complement(13588..13605)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: strong, score: 21.55"
                     /tool="antismash"
     misc_feature    complement(13598..13612)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.83"
                     /tool="antismash"
     gene            13820..14725
                     /db_xref="GeneID:72452267"
                     /locus_tag="FORC47_RS29040"
                     /old_locus_tag="FORC47_p158"
     CDS             13820..14725
                     /codon_start=1
                     /db_xref="GeneID:72452267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016083486.1"
                     /locus_tag="FORC47_RS29040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_p158"
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="WP_000167466.1"
                     /transl_table=11
                     /translation="MTKSLVNLRIDFAFKQLFGTSGSEDILITFLNAMLKNSLESPIMS
                     LQLEDPHLHREHEDDKLSILDVSATLDTGTKVNVEIQLNNNHDMIKRSLYYWGKLYTSQ
                     LQKGMPYSSLSKTITINLLNFVLFPEYEEFHTTGKLWNVQQQKQFSDDIEIHVIELPKL
                     MEQWREEKVNPWEDSFVRWLLLLPANEDEHLTQTLEDIAMNQDPILQKAMNKWERMSQD
                     STFRQAYEAREKTLMDEAAKFAHAEEQGIKKGIEKGIEEGKKAERIQLVCGMYKNGMSV
                     EDIAKFTKLPIEEIREIIQL"
     gene            complement(14871..15845)
                     /db_xref="GeneID:72452268"
                     /locus_tag="FORC47_RS29045"
                     /old_locus_tag="FORC47_p159"
     CDS             complement(14871..15845)
                     /EC_number="1.13.12.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016703 - oxidoreductase activity, acting
                     on single donors with incorporation of molecular oxygen,
                     incorporation of one atom of oxygen (internal
                     monooxygenases or internal mixed function oxidases)
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:72452268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016119387.1"
                     /locus_tag="FORC47_RS29045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_p159"
                     /product="nitronate monooxygenase"
                     /protein_id="WP_089172246.1"
                     /transl_table=11
                     /translation="MKWGIYLNFPQLKIGHMMPKVPIMQGGMGVGISLSKLASAVANAG
                     GIGIISGTGISIDEMRMHIRKAKEKIRNTGYIGVNVLFAMNDFAEKMKAAIEEKVDFII
                     SGAGISRDMYTWGKNADIPVISIVSSAKLARLSERLGAAAVVVEGHEAGGHLGTDRPLF
                     DILPEVVAAVEIPVIAAGGIMTGKDIAHALKMGASGVQMGTRFVASNECDAPLSFKEKY
                     INARLEDTILVKTTVGLQGRAVKNNFTKLIADNNKKIKIKKCINCLKNCSYRFCTLDSL
                     ITSMDGDCENGLVFAGARVNEVKEIMPVQTIINNIMMEYRACI"
     misc_feature    16200..16220
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 24.12"
                     /tool="antismash"
     gene            complement(16260..16490)
                     /db_xref="GeneID:72452269"
                     /locus_tag="FORC47_RS29050"
                     /old_locus_tag="FORC47_p160"
     CDS             complement(16260..16490)
                     /codon_start=1
                     /db_xref="GeneID:72452269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016083488.1"
                     /locus_tag="FORC47_RS29050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_p160"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_089172247.1"
                     /transl_table=11
                     /translation="MFGLGKKRTPFGEYLDYRGIKQQWLVQRTGLSKSLISDLANKKDR
                     IPTLTSATKIIRILKKSDKHIDYQDFWNIDI"
     gene            17278..17676
                     /db_xref="GeneID:72452270"
                     /gene="tnpA"
                     /locus_tag="FORC47_RS29060"
                     /old_locus_tag="FORC47_p161"
     CDS             17278..17676
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:72452270"
                     /gene="tnpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762755.1"
                     /locus_tag="FORC47_RS29060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_p161"
                     /product="IS200/IS605-like element ISBth16 family
                     transposase"
                     /protein_id="WP_000762752.1"
                     /transl_table=11
                     /translation="MKLDSNNHSVFLLYYHLVLVVKYRRNVFDDDMSDYAKDMFVRLSE
                     NYNITLVEWNHDVDHVHILFKAHPNTEMTKFINAYKSASSRLIKRDFPQVKKKLWKEMF
                     WSRSFCLLTTGGSPIDVVKTYIENQSEK"
     gene            17688..18800
                     /db_xref="GeneID:72452271"
                     /locus_tag="FORC47_RS29065"
                     /old_locus_tag="FORC47_p162"
                     /pseudo=""
     CDS             17688..18800
                     /codon_start=1
                     /db_xref="GeneID:72452271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016096850.1"
                     /locus_tag="FORC47_RS29065"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_p162"
                     /product="RNA-guided endonuclease TnpB family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTKQNKAYKFRLYPTED"
     gene            <18942..19505
                     /db_xref="GeneID:72452272"
                     /locus_tag="FORC47_RS29070"
                     /old_locus_tag="FORC47_p163"
                     /pseudo=""
     CDS             <18942..19505
                     /codon_start=1
                     /db_xref="GeneID:72452272"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513581.1"
                     /locus_tag="FORC47_RS29070"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_p163"
                     /product="SPASM domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="TIGR04085 (E-value: 2.6e-18, bitscore:
                     60.1, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="KISMEPVICNPREPYALGEKDLLEIYNQYEILSKEMLNREEKGDA
                     FTFYHYMLDLSEGPCVQKRISGCGSGTEYLAITPWGEIFPCHQFVGEEEYSMGNIWDGI
                     TKAEIESQFKGNNCYSKPECQVCWAQLYCSGGCPANTIHATCSLKGTHEFSCKIFRKRI
                     ECSMMVKVAQSIRAMKKEEQAIVQ"
     gene            complement(19651..20046)
                     /db_xref="GeneID:72452273"
                     /locus_tag="FORC47_RS29075"
                     /old_locus_tag="FORC47_p164"
     CDS             complement(19651..20046)
                     /codon_start=1
                     /db_xref="GeneID:72452273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016119385.1"
                     /locus_tag="FORC47_RS29075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_p164"
                     /product="DUF3221 domain-containing protein"
                     /protein_id="WP_089172245.1"
                     /transl_table=11
                     /translation="MLSKKQKLVTVVTTLTLGCGLAFGLTPTSADSISNPTPIKEEKVR
                     IQIPFTGYVISADDNYLVVANTNTKEEALSYQNNWWELASQNKILRVPITSKDNYSVGE
                     KLNIFSVGWTHSIPPIAVMPVIEKIIE"
     misc_feature    complement(20128..20145)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: strong, score: 21.55"
                     /tool="antismash"
     misc_feature    complement(20138..20152)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.83"
                     /tool="antismash"
ORIGIN
        1 acatgtaaaa cgagctgtaa atgatttaat tttatcaaaa acatttgata atggtatgat
       61 ttgtgcttct gaacaaacaa tcattgtaga taaagaaatc tatactagtg taaaaaaaga
      121 aatgcaagac aacaaatgtt attttgttac cgaagaagag agaataaaat tagagaagtt
      181 tgttgttaat gaaaatacat gtgcagtaaa tagtgatatc gttgggaaat cagcacatta
      241 tattgcatca ttagtaggca ttaaggtacc agaagataca aaaatacttg tagctgaaat
      301 taagggagtg ggtgcagaat atccactatc acgtgaaaaa ttgagcccag tattagcctg
      361 tattaaagca aattcacgag aagaaggatt taaatactgt gaagaaatgt tgaatttagg
      421 tggcttaggg cattcagcgg ttattcattc tataaataaa gaagtacaaa aacaatttgg
      481 tttaagaatg aaagcttgtc gccttattgt aaattcaccg tcagcacaag gcgggattgg
      541 tgatatatat aacgcattta ttccatcttt aacattaggt tgtggatcat acggtaaaaa
      601 ttctgtttct caaaacgtaa cagctacaca tttaataaat gtaaagcgtt tggcgaatag
      661 aaaaaataat atgcaatggt tcaaattacc acctaaggtt tttttgaaaa acatgcgaca
      721 caatatttag ctaagatgcc aaacatttca cgagcattca ttgtaacgga ttcaggaatg
      781 atagaactgg gatatgtgaa cacagttaca cattacttac aacagcattt aaatgatgta
      841 aaagtaggtg ttttttcaga ggtagaacca gatccatcag atgaaacagt attcaagggt
      901 ggtgagatga tgagaagctt caaacctgat gtaattatcg cattgggcgg aggttcagca
      961 atggatgcag caaaaggaat atggctattt tatgaatatc cagaaacaag attctttgga
     1021 atcaaacaaa agtttttaga tattagaaaa cgtacatgta aatttctaac actagggtaa
     1081 aaagcacagt ttgttgcgat tccaacaaca tcaggaacag ggtcagaagt gaaaccattc
     1141 gcggttatta cagataaaaa aataatgtaa aatatccact tgctgattat gaattaacac
     1201 cagatgtagc gattattgat ccacagtttg taatgacagt gccaccccat gtaacagcag
     1261 acactggaat ggatgtgtta acacatgcga ttgaagcata cgtgtctatt atggcaaata
     1321 actagattgg ccttaaaagc cattgatcta gtatttaaat atttaccgag agcatataaa
     1381 aatggaaatg atgaagaagc acgtgagaaa atgcataatg tttctgcaat tgcaggtatg
     1441 gcttttgcaa atgcatttct tggtattaat catagtttgg cgcataagct tggaccagaa
     1501 tttcacattc cacatggacg cgctaacgca atcttaatgc cgcatgtaat tcgctataat
     1561 gctattaagc cgagagaaca tgcattgttc ccaaaatatg agcattttgt ggcagatgaa
     1621 cgttatgcat atattgcaag aacattgggg ttgccagcaa gtacagtaga agaaggggta
     1681 gaatctcttg tacaagcaat tatcagcctt ggaaaagaat tgaatattaa tatgagtatt
     1741 gcaggataag gagtaaaaca agaagcattt gaaaatgttg tggatgtctt atcggaaaga
     1801 gcatttgaag atcaatgtac accagcaaat ccgaaactcg cattgacttc agaattaaaa
     1861 gaagtatata accaagcata taaaggtgtg taataagtta agtaggtata actttttaag
     1921 ttcatagatt ttgtatttga tatttgtaaa tgtattgtat atgggtgtta aggggaaata
     1981 tatattataa acagctgtgt tttaaataga acatctaaca aaaatgctgc ctagatgacc
     2041 tgtatgtagg taagacagga gtgtacaaaa attatgtcta actataagaa attaaatcaa
     2101 gtaattgaaa aaagaggaat taatatcgct tgttaagcag tatggattca ctcaggaaac
     2161 ggtaatttgt tatagtagag aactagattt attactatat gatttaatga aatttaatag
     2221 aaataataag taaattaaaa ttatataaaa aagaaataaa atataaatac ttaagatatt
     2281 tttaaaatat ttttaagata tttttatctt gatttcatct atttggtgag ggatttttaa
     2341 ttgctaaaaa cttatgcgtg ataaatctca caacaaaaat gctcatataa ttttacaata
     2401 tagtatgtaa gttgatagga actttttttg atagatcgtg atcacaataa agaaccattt
     2461 attgtaatat gggagttaac aagagcatat gaagtgaact acccgccact taacgtccta
     2521 acatacagtt tgaagtgggg gcttctcggt taatcgttac ttttgatagc taacgaattc
     2581 gtcctaagac agccgagcta actcccttgt tccaaaggtt gttttattac tatttatgct
     2641 aataggcgta ttgcctcatt tttgatattg atagctgcgc tataatctct atcaagattt
     2701 acacctcata tacaagaata gactcgttca gataatgtta tatttttcac gcttccaaaa
     2761 ctgctacatg cttttgtgga aggaaaccat ttgtttattt tcacaactta ttaaacggat
     2821 ttgggattga gataccaaaa tcacttttaa caattccaac acaaggtgga atcgttaact
     2881 taccagcagt aatcattact ttgttattaa cttggttatt atcaaagggc gcgaaagaaa
     2941 gtaagcgagt gaataacgca atggtattaa taaaaattgg tattgttgtt ttgttcattt
     3001 cagttggtat attttacgta aaaccagaaa actggatccc gtttgcacct tatggtataa
     3061 gcggaatctt tgccggagga gctgcagtat tttttgcgat ggttggtgtg tcatttatta
     3121 ttcttcgtaa aacacatccg aatttaaaac gaggtttcat ggtactactg gtaccaagct
     3181 taccgattat tttaataaca tgttgcttat tcttaatggt aaatctacct ttaaaaactt
     3241 gggtttattt cggtatttgg ttatttatag ggggaatagt atattttatg tattctaaaa
     3301 gacatagtca attaaacaaa ctataaatga tatatatcag agacaaaggt tatcacgacc
     3361 tacatgtttg aacaagtagg attcttctct tttgggaagt accttttctt tttataaaaa
     3421 attcaattaa aagaacttga aagtttatgt tatacgtaaa aaaacgaatc tattttcaaa
     3481 atagattcgt ttttttatct cctaataact taaaaactta aactcaaata gaaaaaatga
     3541 atgaattatt cggatgatag taaatgcctg agtgatttca atgtatacat gacgaatcag
     3601 tttgtattta tttccttgat aggattttac ataatattaa ttttttgtga attattaatc
     3661 tgaaaataat ttgatttaaa gtattattca tacgaaatga atacctttat gtaatttatt
     3721 tgatttataa gatagttaag aataccaaat caatacataa aagctcatta ttgattgata
     3781 ttttataaag ttgtattaat atgtgtcata aaataatatc aaaatataat tataaataga
     3841 ataagggagg actatgtaaa aaagtaataa atacaagttc atgaactgtt tttgcacgta
     3901 agtacatgct aaagaaacga aaacttttaa atttatcaag gaaatgagag ggagatagta
     3961 tggggaataa atcaaagcat aaaaccaaaa gaatacttgc agctactgca acattaacta
     4021 tgcttgcttc tggaatggtt tcttcatcag atgtctttgc agaggaaacg cagcagcaaa
     4081 aaaagttatc gacatcactg caaggagaaa agtcagttaa atcagaaaat agaacatata
     4141 cagtcccagg aaaaggggat gttgaggtac tgaaacaaca agaaagaaaa agttggacat
     4201 ttagtcccta tgagcccact ggtttatatg caaatccaaa tgaacaaata acgattaatg
     4261 ttgaaggaac tcaaaatatt gatgcataca ttggaacgcg ttcgtatgat gctgcttgga
     4321 atgaagattc caaaataaaa tcatttacat taaaacccgg tataaataca attcaatctc
     4381 caaatggggg gatgatttat ttttataata aacaacaagg tggtaccatt cgaacaacag
     4441 tcacaacagg tggaacgact acccctttct ttgaactagg taagcatacg aaacaagatt
     4501 taataaacat gctggaccaa tatccaaatg cacatgcagt ggagttaaaa ggagaacgtg
     4561 tattaattac ggctagccct gcacgtgtta agaaatattt gttgggttct aatacagatc
     4621 ctgtacagct cttaaaaaag atagatgaag ctactcgaat tcaagataaa gtagctggat
     4681 tatccgagga acaagtagat aaacattatc tgcattatgt agaagataat cattctcaag
     4741 gttattatat gtatgcattt cctcagcgaa ctgcatatgt aggagatgca atccaatatg
     4801 ttttagatat taataaattt ataaaagaag gctgggggcc ttggcatgag acaggacatc
     4861 taagacaaca atggccttgg actttttata atatgacaga agtacaaaat aatatttaca
     4921 gcctttctgt agaaaaagca tttaatcaac catccaattt agagaaaagt ggaatttatc
     4981 caaaagcgtt tcaatatcta gaacaaacga ataagaatta tgatgaaatt agtgatgctt
     5041 ttgttaagct tgttatgctt tggcaattac aacttgccta tggtgaggat ttctatccaa
     5101 aattgcatca attgtataga gatatgcctt caagtgaact tccacaaact gatgaaaaca
     5161 aaaaacaatt atttatgatc tcagcatcaa aagtagctaa acaaaatttg attcctttct
     5221 ttgagaagtg gggattacgt ccaaacaacg ataccattca aaaagtggct gcactaggat
     5281 atccaatttt aacagcagag atttggaagg gtacagattc taatccaata aaaccagata
     5341 taccgaactc ttctagtatt ttagaaggaa agcagtttgc atggtcactg aaagggattg
     5401 gagattttga atttgcgaaa gtaaatttaa ataaatcaac agaagaaatg caaattgatt
     5461 taaaagcagg tgtaccacat aactactttg atagtacata tgcaagtatt aaagtacaaa
     5521 atgcatcagg gaaagtagta tacaataaag acatttatgg aaacaaacaa caaaatgctg
     5581 aatcgcaaaa agtttcagtc aaagtaggag attatattga gttaacacat caagaaggtg
     5641 tgcatagagc tactctcaca aatgcagata atagtaaaca agagagcttt ggaaaaaaag
     5701 ccatatacga agttacaaaa gaaggtctga agaaagtaga aaaaatgcca gaagcaacaa
     5761 ttctagatgg aaatcaattt gcatggtcgc taaaaggaat ctgtgatttc gagtttgcta
     5821 aaatcaattt caataagtcg acagaagaaa tgcaagtgga cttaaaagca ggcgtaccgc
     5881 ataactactt tgatagtaca tatgcaagta ttaaagtaca aaatgcatca gggaaagtag
     5941 tatacaataa agacatttat ggaaacaaac aacaaaatgc tgaatcgcaa aaagtttcag
     6001 tcaaagcagg agattatatc gagttaacac atcaagaagg tgtgcataga gctactctca
     6061 caaatgtaga taatagtaaa caagagagtt ttggaaaaaa agccatgtat gaagttacaa
     6121 aagaaggcct aaagaaagta gagaaaatgc cagaaacaac agttttagat ggaaattaat
     6181 ttgcctggtc tttaaaagga tataatgatc gagaaatcgc aaaagtagag tataacaaag
     6241 caacagaaaa aatgcagatt aaattagaag cgggtatacc ccattcctat tttactagta
     6301 cgtatgcaag cattaaagtc cagaactcat cgggcaatat tttgtacaat aaagaaattg
     6361 taggaaatag acaacaagct gttgaaggcc aaaccgttcc catcaaagta ggagattata
     6421 ttgagtttac tcatatagag ggagaagcac aaaaggaaaa gacacgcgct acacttacta
     6481 atcttgataa tagtaaacag gaagatatag ggaagaaaag aacatataag gttacctcta
     6541 tgggattatt aataaagtca tagaggtaac cttaaaactt aaattgtaaa tatatatatt
     6601 atattaaaat cttaactatt atatgcatta aacaatgctc aagagaaaat agattggcgg
     6661 gtaaagtatg aacatattca aagggtttct aattgcttca attgcaatga caacattctt
     6721 aggaacagat caaatactac cagatgatag tattcataat aaagtttatg cggagtccta
     6781 taatgctaca aacaaagaaa ctgattctaa taaaagagat tcacaggagg gacaattaat
     6841 tgtaaagttt aaaaatgaaa tggacttacc ttatgaagat ggcattgaga aacgaataaa
     6901 aaatggtaat tatgataata atttaaagaa gttattttcc gaaaatacgg aacttacttt
     6961 gaatcgcctg ttttcatctg taaatccgat agagattgaa aagttatcat tacattctaa
     7021 atcatttgct aatcaatcag ctgaaaattt attaaattat tatattgtac aagctcctaa
     7081 taatatagaa atagaattat tgctgaaaaa atttgaaaca tcacctcttg tagaggaggc
     7141 ctatatacaa gaaaaacaaa tcttaacacc ccctgaagta caattaccag gtttatctgt
     7201 taatccatac gatgatccta gatttaaaaa tcaaggatat cttgaagcgg caccaaaggg
     7261 aattaatgcc tcgcatgctt ggagcattaa aggtggtgac gggaaaggta caacttttgt
     7321 ggatatggaa tatgggtggt tattgaacca tgaggattta gtcaatcaaa atataaagct
     7381 tatgtctgga caaaatataa gtcagcatag agctcacggt acttctgtat taggaattgt
     7441 ttcatccgaa gataatcaaa ttggaaatat tggaattgca ccaaaagcaa atgtaaaagt
     7501 aatatcccaa attagggata atggaattta taatacagcg gatgctattt taagtgctgt
     7561 acataattta caagcgggag atattctttt attagaggca caagcttcgt atgatgggta
     7621 tggggataaa tatttacctg tagaggtaca tccagatatt tttgatgcaa ttcgtgttgg
     7681 tgcagataaa gggattatta ttatagaagc tggcgcaaat ggttcaaacg acttagataa
     7741 ttttaaagat cgtaatggaa aaaagatctt aaatcgaaat agtccagact tcaaggattc
     7801 aggtgctatt atggttgggg cgggatcatc aactgttcca cataagcgtt tatggttttc
     7861 aaattatgga agtcgattag atgtatatgg atggggagaa aatgttgata caacatcagc
     7921 aaatccaagt caaaatacta caaatttata tacatcaaca tttagtggaa catcaagtgc
     7981 ttcaccaatt attgctggag cagcaacttc gattcaaggt attgctaaag aacatcgagg
     8041 ttctccttat acaccagccg aattaagaaa tatcttaagt aatccaaata caggaacaaa
     8101 atctcaagat ccgtggaatg atagaatagg tgttttacct gatctaaaat ctatattaga
     8161 taacttaggt tttaattcag atataccgag ttcttctagt attttagaag gaaagcagtt
     8221 tgcatggtcg ctgaaaggga ttggagattt tgaattcgca aaagtaaatt taaataaatc
     8281 aacagaagaa atgcaaattg atttaaaagc aggtgtacca cataactact ttgatagtac
     8341 atatgcaagt attaaagtgc aaaacacatc aggtaaagtg gtctataaca aagagattta
     8401 tggaaacaaa caacaaaatg ctgaatcgca aaaagtttcg gttaaggtag gagactatat
     8461 agagttaaca catctagaag gtgtgcatag agctactctc acaaatgtag ataatagtaa
     8521 acaagagagc tttggaaaaa aagccatata cgaagttaca aaagaaggcc tgaagaaagt
     8581 agaaaaaatg ccagaagcaa caattctaga tggaaatcaa tttgcttggt cgctaaaagg
     8641 aatcagtgat tttgagtttg ctaaaatcaa tttcaataag tcgacagaag aaatgcaagt
     8701 tgatttaaaa tcaggcatac cacatcatta ttttaatgaa acatatgcga gtattaaagt
     8761 acaaaatgca tcagggaaag tagtatacaa taaggatatt tacggaaaca aacaacaaaa
     8821 tgctgaatcg caaaaagttt cagtcaaagt aggagattat atagagttaa cacatctaga
     8881 aggtgtgcat agagctgttc tcacaaatgt agataatagt aaacaagaga gttttggaaa
     8941 aaaagccatg tacgaagtta caaaagaagg cctaaagaaa gtagagaaaa tgccagaaac
     9001 aacagtttta gatggaaatc aatttgcttg gtctttaaag ggatataatg atcgagaaat
     9061 cgcaaaagta gagtataaca aagcaacaga aaaaatgcag attaaattag aagcgggtat
     9121 accccattcc tattttacta gtacgtatgc aagcattaaa gttcaaaact catcgggcaa
     9181 tattttgtat aataaagaaa ttgtaggaaa tagacaacaa gctgctgaaa accaaaccgt
     9241 tcccgtcaaa gtaggagatt atattgagtt tactcatata gagggagaag cacaaaagga
     9301 aaagatacgt gccacactta caaatcttga gaatagtaaa caggaatttg tgggtaagaa
     9361 aaaaacatat caagttactc ctacgggatt attaataaaa tagattaaaa ggatgtctaa
     9421 aaaaatagaa tttttttgga catctttttt attattaaaa aagcattaat tattgatagt
     9481 gatgtatgat gaattctaaa ggcccattaa atattatata tatctataca taatataact
     9541 aatgttccaa ggatcaacac atctattttt gtttaatcat gttatacttt tcacaagtga
     9601 aacgctacaa tatcaaatcc tagttttatg acatccttct gttgccacag tctataaaaa
     9661 gtcaattcca ttggggttga ctttttatag ttgtagcaga aagctataaa cgtccatatt
     9721 ttttaatagg atagacactt taatttcacg taccgtattt atatataaat agttacagta
     9781 aacaatagtc tatatgtaac tgttaaataa ataatatttg gtcttctcgt gatatttcaa
     9841 attaaggtta aaagaaagga aagtaaaggt agcttgttaa tatatcaaga tattagtgat
     9901 aattggtgag gaattgaaga actacggtat atgattgtga tttatttcat aatcatatac
     9961 cgtagttctt caaaattatt tcaaaaggag gttatagata atgaaaagaa ttataacact
    10021 gagcacttgt aaactgcaag atactataaa acatggtgga tgtggtgcat gtcagacatc
    10081 ttgtcagtcc gcttgtaaaa cctcatgtgg agttgcaaat caaaagtgtg aaaatacaat
    10141 ggaaaaagag ccatcgattt tctattagaa aactcaggta atcatcgaaa tctcgatgtt
    10201 gatttttttg gtggggagcc actcatggcg tggaagactt tcaaacagat tgtcgcctat
    10261 gcaagaaata aagaaaaaga gtacaaaaaa acttttcgtt ttacctttac tacaaatggt
    10321 atgctgctta atgatgagat tactgacttc ttgaatcagg aaatgcacaa tgttgtatta
    10381 agccttgatg gaagaaaaaa agttcatgat tatctacgta aaactgtcaa tgggaagggt
    10441 agctacaatc atattgttcc aaagtttcag gaatttgttg aaaagcgtgg agataaggaa
    10501 tactatgtac gtggcaccta tactcataat aatgtcgatt ttaccaatga tatttttcac
    10561 atcgctgatc taggttttaa cgaatttccg gaaagaattc tccttcctca agcgtgtgaa
    10621 gggtgtagcc caacgatagg tgggagatga atttcggttt ggcgtagcca aaaggttttc
    10681 ctttttattc tgcctctgat ataatcagtc ttataaatta taaaggttgg tatataaatg
    10741 aaattagata gtaataacca ttcagtattc ttgttgtatt atcaccttgt gttggtcgtg
    10801 aaatacagaa gaaatgtgtt tgatgatgat atgtcagact atgcaaaaga tatgtttgtt
    10861 cgactatctg aaaactataa catcacatta gttgaatgga atcatgatgt agaccatgtt
    10921 catattttgt tcaaggcaca ccctaataca gaaatgacaa aattcatcaa tgcttataaa
    10981 agtgcaagtt ctcgacttat taaaagagat tttccacaag tgaaaaagaa actttggaaa
    11041 gagatgtttt ggtcaagaag tttttgcttg ctaactactg gtggttcgcc aatagacgta
    11101 gtaaaaacat atattgaaaa tcaaagtgaa aagtgaggtg aaatgatatg acaaagcaga
    11161 ataaagcata taaattccgt ttgtatccaa cagaagacta agcacatctt atgcgtaaaa
    11221 ccttcggttg tgtacgtttc gtgtataaca gaatgttagc tgaacggaaa gaagcgtatg
    11281 aaaaacataa agatgataag gatcaactaa agaaacaaaa gcttcccacg cctgcaaaat
    11341 acaaagcaga atttgagtgg ttaaaagaag tggattcatt agctttggca aatgctcaac
    11401 taaacttgca aactgcctat aagaatttct tttgtggtca aaatgacttc ccaacattca
    11461 aaagcaaaaa agacagaaag tcttatacaa cgaatgtagt gaacggaaat attatgttgc
    11521 ttaacggtca tatcaaattg ccaaaactga aaatggtacg tatcaaacag catagagaaa
    11581 taccacaaga ccatataatc aagtcatgta cgatttctat gacacctact ggtaaatact
    11641 atgtatccat tttgactgaa tacgaaaaag agatcgtaca aaaagaagta gaaacagttg
    11701 ttggattaga ctttgcgatg gatcaattat acgtcagttc tgaggatgag agagccaatt
    11761 atcctaagtt ctatcgtgaa atgttagacc gattagcaaa tgctcaacga gtattagcaa
    11821 gacgtacaaa aggttcaggg cgttgggata aacaacgtat ccgtgtagct aagctgcatg
    11881 aaaaagtagc aaaccaacgt aagaacttcc ttcatcataa gtctaaagag ttagctactc
    11941 attttgatgt tgtagctatt gaagatctaa atatgaaggg aatatcgcaa gcacttcatt
    12001 ttggaaaaag cgttgctgat aatgcttggg gtatgttcac gtctttctta gcttataaac
    12061 taaatgaaca aggcaaacag cttgtgaaaa tagacaaatg gtttccctcc acaaaaaaat
    12121 gtagcagttg tggaaatgtg aaaaatatgt cattgtctga gcgagtctat tcttatatat
    12181 gcggtgtaaa tctcgataga gattataacg cagctatcaa tatcaaaaat gaagcaatac
    12241 gcctattggc gttagcatag atagcaataa aataaccctt ggaacaaggg agttagctcg
    12301 gctgtcttag gacgaattcg ttagctacca aaagtaacga ctaaccgaga agcacccact
    12361 tcaaacagtc cgctaggacg ttaagtggcg ggtagttcac taagatctca atggaaccag
    12421 ttatctgtaa tccacgagaa ccatatgcgc tcggtgaaaa agatcttttg gaaatttaca
    12481 atcaatatga aattctctcg aaggaaatgc taaaccgtga ggaaaaagga gacgctttta
    12541 ctttctatca ttacatgctt gacctttcag aaggtccatg cgttcaaaag agaatttctg
    12601 gttgcggttc tggaactgaa taccttgcta ttaccccgtg gggggagata tttccttgtc
    12661 atcagtttgt tggagaagaa gaatatagta tggggaatat ctgggatggc attacaaaag
    12721 cagagataga gtctcagttt aaggggaata attgctattc aaaaccggaa tgtcaggtat
    12781 gttgggcaca gctttactgt agcggcggtt gcccagctaa tacaatacat gcaacgtgtt
    12841 cccttaaggg aacacatgag ttcagctgta aaatcttccg caagaggata gaatgttcta
    12901 tgatggttaa agtagctcaa tccattagag ctatgaagaa ggaagaacaa gccatagttc
    12961 agtaaataca aaagtgcaca agcgttgtta tagcataaat ttataaagat agttacaaac
    13021 aaaaattctt tagtccagtt tagaataaat gagtttaaaa gaagatagcc atttataaat
    13081 ggctatcttc ttttgtaaaa aaaatataat ttattcaatt attttttcaa taacaggcat
    13141 aacagcgatt ggtggaatag agtgggtcca tcctacggaa aatatattta gtttttcacc
    13201 tacgctatag ttatctttgc tagtaatagg aacacgtaaa attttattct gagaagctaa
    13261 ttcccaccaa ttattttgat aagaaagtgc ctcctctttt gtattagtgt tagctacaac
    13321 caaataatta tcatctgctg aaataacata tccagtgaaa ggtatctgta ttcttacttt
    13381 ttcttcctta ataggagtag gattacttat agaatctgcc gaagtaggag ttaatccgaa
    13441 agctaatcca catcctagcg tcagagtagt aaccactgtt actaattttt gtttttttga
    13501 aagcataata taaatccccc ttatatttta tccgtacacc atcacctttc tattttttat
    13561 atagaaagcc tttttatatc cctaaattta acaattatgt aacaaataat ccattgtttt
    13621 tttgaatggg tattatttaa agataatata tgttataatt aaccaaatta actattaatt
    13681 gtacctttat cttctagtga acatatattt tcgaaaagaa tgatagcgtt atcttttgta
    13741 aatgttccta tttgcatgat tacctaattt ttatgtacaa taaagaaaag agagtttctt
    13801 agacaggaag aggaaagtca tgaccaagtc attagtaaat ttacgaattg attttgcttt
    13861 taagcaatta tttgggacaa gtggtagtga ggatattctt atcacatttt taaatgccat
    13921 gttaaagaat tcattagaat cgcctattat gtcactacaa ttagaggatc cacatttaca
    13981 tcgagaacat gaggatgata aattatcaat tttagatgtc tcagccacat tagacacagg
    14041 tactaaagta aacgtagaaa ttcagctgaa taataatcac gacatgatta aacgaagttt
    14101 gtattactgg ggtaaattat atacttcaca gttacaaaaa gggatgcctt acagctctct
    14161 cagtaaaaca attactatta atttgttaaa cttcgtactt tttcccgaat atgaggaatt
    14221 tcatacaacg ggaaagctat ggaatgtaca acagcaaaag cagtttagtg atgatataga
    14281 gattcatgtt atagagcttc ctaaactaat ggaacaatgg cgggaagaga aggttaatcc
    14341 gtgggaagat tcatttgttc gttggctgtt attacttccg gcaaatgaag atgaacacct
    14401 aactcaaaca ttggaggaca ttgcaatgaa tcaagatccg attttacaaa aagcaatgaa
    14461 taagtgggag cgaatgagtc aagattcgac attccgacaa gcctatgaag cgagggaaaa
    14521 aaccctaatg gatgaagctg caaagtttgc tcatgcagag gagcaaggaa tcaaaaaagg
    14581 tattgaaaaa ggtattgaag aaggcaaaaa agccgaacgt atacaattgg tatgtggtat
    14641 gtataaaaac ggaatgtctg tagaggatat tgcgaaattt acgaagttac ctatagaaga
    14701 aataagggaa attatccaat tataaataaa aaagaacacc tacagcattt gtaggtgttc
    14761 ttttttatga ccaataatgt ccggagcata attattagtt gatgtatcgt caggaaaata
    14821 agaacttaca acattaaata atttttaaag aactatacat ggattctacc ttaaatacat
    14881 gctctatatt ccatcataat attgttaata attgtttgga cgggcataat ctctttgact
    14941 tcatttactc gtgcacctgc gaaaacaaga ccattttcac aatcaccatc catagaggtt
    15001 atcaaagaat ctagcgtgca gaaacgataa gaacagtttt ttaagcaatt tatacacttt
    15061 tttattttta tctttttatt attatcagct attaatttag taaagttatt tttaaccgca
    15121 cgaccttgaa gaccgacagt tgttttgact aatatagtat cttctaatcg agcatttata
    15181 tatttttcct taaaggatag tggtgcgtca cactcattac ttgcaacgaa tcttgtaccc
    15241 atttgcacac cagatgcacc catttttaag gcatgcgcaa tatcttttcc agtcataatt
    15301 cctccagcag caattacggg aatttcgact gctgcaacta cttccggtaa tatatcgaat
    15361 aaaggtcgat cggtacccag atgtccgcct gcttcatgac cctctactac aacagcggcc
    15421 gcacccaagc gttcagataa tctagcgagt ttggctgagg atactattga aataactggt
    15481 atgtcggcat ttttccccca agtatacata tctcgtgaaa tgccagcacc agatatgatg
    15541 aaatcaactt tttcttcaat ggctgctttc attttttcag caaaatcatt catagcaaaa
    15601 aggacattta ctccaatata accagtgttc cggatctttt cttttgcctt cctaatatgc
    15661 attctcattt catctatgga aataccagtt cctgatataa tcccaattcc tccagcattt
    15721 gcaactgcag atgcaagttt acttaatgaa atgcctacgc ccattcctcc ctgcataatt
    15781 gggacttttg gcatcatatg accgattttt aattgtggaa agttcaagta aataccccat
    15841 ttcattaatg ttattagagt agatctgtta aaccctctca gtttaacaca gtgtttggaa
    15901 caaaaactag gaaattaata cctactacta gtagtttgta acgttttttg ttgattttca
    15961 caaaatgttc gaatagtgcg ctataaattt tagaataata tcaaatgtat attaaggctt
    16021 ctggataaaa aacgcattta aagaattgat atgtcaaaaa tgaagtggga tgtaatcatt
    16081 aattattttg agtagagata tgaacagagc taaatagaaa tttgtatcct ttttaataaa
    16141 agtaattttt gtattataag tgttaaataa tcaatagtta taaagggaaa aatctatgtt
    16201 tttagtaatc tagacgattg gattagagac aattagatgc gtagtacatt ctagaggttt
    16261 taaatatcaa tattccaaaa atcttgataa tcaatatgct tatcagattt ttttagtatt
    16321 ctaatgattt tagttgcaga tgttaaagtg ggaatacgat cctttttatt tgctaaatca
    16381 cttatcagag atttacttaa tccagttctt tgtacaagcc attgttgttt gattcctctg
    16441 taatctaaat actcaccaaa tggagttctt ttttttccta gaccaaacat aaagaatccc
    16501 tcctaattaa aaatagcgta taaatagctt gtacaaaatt ccataaattt aaacttttgt
    16561 ccataaatat ggaattataa gttagaacaa agcatagaat aatataaata aaatgaaaaa
    16621 atatggaata attttgagga atctagcatt catagtaata gctacaagtt gctgatacac
    16681 tatcctaatg gcaacttgtt gcaaagggta ttactaaaat aaaaaaatct gaaattcctt
    16741 acgtcagaag gatcttcaga ttttttcttt tttagatctt taatttgtag acacgtattt
    16801 tatatattat tatgcataat atggcgaatg agtaggatgg atcatctgct tatatagttt
    16861 gatcgacctt gtcactaagc atataaatct gttttagata tgatgaaagg aaatactaac
    16921 aaaaaatgtg gaatccaaaa tcagtcatat ctggtccagt atactcatca ctttttaccc
    16981 agctgttgag ttatgagttt gtattgaaaa aagtacagtc ggccagtttg tgtaacaaaa
    17041 aatatttcta tcccgtctac aaatttagtt actttttcac tcatatgact aggcttgtag
    17101 gattcatatt ttttttttaa cgaatttccc gaaagaattc tccttcctca agcgtgtgaa
    17161 gggcgtagcc caacgatagg tgggagatga atttcggttt ggcgtagcca aaaggttttc
    17221 ctttttattc tgcctctgat ataatcagtc ttataaatta taaaggttgg tatataaatg
    17281 aaattagata gtaataacca ttcagtattc ttgttgtatt atcaccttgt gttggtcgtg
    17341 aaatacagaa gaaatgtgtt tgatgatgat atgtcagact atgcaaaaga tatgtttgtt
    17401 cgactatctg aaaactataa catcacatta gttgaatgga atcatgatgt agaccatgtt
    17461 catattttgt tcaaggcaca ccctaataca gaaatgacaa aattcatcaa tgcttataaa
    17521 agtgcaagtt ctcgacttat taaaagagat tttccacaag tgaaaaagaa actttggaaa
    17581 gagatgtttt ggtcaagaag tttttgcttg ctaactactg gtggttcgcc aatagacgta
    17641 gtaaaaacat atattgaaaa tcaaagtgaa aagtgaggtg aaatgatatg acaaagcaga
    17701 ataaagcata taaattccgt ttgtatccaa cagaagacta agcacatctt atgcgtaaaa
    17761 ccttcggttg tgtacgtttc gtgtataaca gaatgttagc tgaacggaaa gaagcgtatg
    17821 aaaaacataa agatgataag gatcaactaa agaaacaaaa gcttcccacg cctgcaaaat
    17881 acaaagcaga atttgagtgg ttaaaagaag tggattcatt agctttggca aatgctcaac
    17941 taaacttgca aactgcctat aagaatttct tttgtggtca aaatgacttc ccaacattca
    18001 aaagcaaaaa agacagaaag tcttatacaa cgaatgtagt gaacggaaat attatgttgc
    18061 ttaacggtca tatcaaattg ccaaaactga aaatggtacg tatcaaacag catagagaaa
    18121 taccacaaga ccatataatc aagtcatgta cgatttctat gacacctact ggtaaatact
    18181 atgtatccat tttgactgaa tacgaaaaag agatcgtaca aaaagaagta gaaacagttg
    18241 ttggattaga ctttgcgatg gatcaattat acgtcagttc tgaggatgag agagccaatt
    18301 atcctaagtt ctatcgtgaa atgttagacc gattagcaaa tgctcaacga gtattagcaa
    18361 gacgtacaaa aggttcaggg cgttgggata aacaacgtat ccgtgtagct aagctgcatg
    18421 aaaaagtagc aaaccaacgt aagaacttcc ttcatcataa gtctaaagag ttagctactc
    18481 attttgatgt tgtagctatt gaagatctaa atatgaaggg aatatcgcaa gcacttcatt
    18541 ttggaaaaag cgttgctgat aatgcttggg gtatgttcac gtctttctta gcttataaac
    18601 taaatgaaca aggcaaacag cttgtgaaaa tagacaaatg gtttccctcc acaaaaaaat
    18661 gtagcagttg tggaaatgtg aaaaatatgt cattgtctga gcgagtctat tcttatatat
    18721 gcggtgtaaa tctcgataga gattataacg cagctatcaa tatcaaaaat gaagcaatac
    18781 gcctattggc gttagcatag atagcaataa aataaccctt ggaacaaggg agttagctcg
    18841 gctgtcttag gacgaattcg ttagctacca aaagtaacga ctaaccgaga agcacccact
    18901 tcaaacagtc cgctaggacg ttaagtggcg ggtagttcac taagatctca atggaaccag
    18961 ttatctgtaa tccacgagaa ccatatgcgc tcggtgaaaa agatcttttg gaaatttaca
    19021 atcaatatga aattctctcg aaggaaatgc taaaccgtga ggaaaaagga gacgctttta
    19081 ctttctatca ttacatgctt gacctttcag aaggtccatg cgttcaaaag agaatttctg
    19141 gttgcggttc tggaactgaa taccttgcta ttaccccgtg gggggagata tttccttgtc
    19201 atcagtttgt tggagaagaa gaatatagta tggggaatat ctgggatggc attacaaaag
    19261 cagagataga gtctcagttt aaggggaata attgctattc aaaaccggaa tgtcaggtat
    19321 gttgggcaca gctttactgt agcggcggtt gcccagctaa tacaatacat gcaacgtgtt
    19381 cccttaaggg aacacatgag ttcagctgta aaatcttccg caagaggata gaatgttcta
    19441 tgatggttaa agtagctcaa tccattagag ctatgaagaa ggaagaacaa gccatagttc
    19501 agtaaataca aaagtgcaca agcgttgtta tagcataaat ttataaagat agttacaaac
    19561 aaaaattctt tagtccagtt tagaataaat gagtttaaaa gaagatagcc atttataaat
    19621 ggctatcttc ttttgtaaaa aaaatataat ttattcaatt attttttcaa taacaggcat
    19681 aacagcgatt ggtggaatag agtgggtcca tcctacggaa aatatattta gtttttcacc
    19741 tacgctatag ttatctttgc tagtaatagg aacacgtaaa attttattct gagaagctaa
    19801 ttcccaccaa ttattttgat aagaaagtgc ctcctctttt gtattagtgt tagctacaac
    19861 caaataatta tcatctgctg aaataacata tccagtgaaa ggtatctgta ttcttacttt
    19921 ttcttcctta ataggagtag gattacttat agaatctgcc gaagtaggag ttaatccgaa
    19981 agctaatcca catcctagcg tcagagtagt aaccactgtt actaattttt gtttttttga
    20041 aagcataata taaatccccc ttatatttta tccgtacacc atcacctttc tattttttat
    20101 atagaaagcc tttttatatc cctaaattta acaattatgt aacaaataat ccattgtttt
    20161 tttgaatg
//
