LOCUS       NZ_CP017060            25239 bp    DNA     circular CON 03-MAY-2024
DEFINITION  Bacillus cereus strain FORC_047 chromosome, complete genome.
ACCESSION   NZ_CP017060
VERSION     NZ_CP017060.1
KEYWORDS    RefSeq.
SOURCE      Bacillus cereus
  ORGANISM  Bacillus cereus
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 5365433)
  AUTHORS   Lee,J.-H., Kim,Y.-T., Ku,H.-J., Kim,H., Kim,H., Choi,S.-H. and
            Ryu,S.
  CONSRTM   Food-borne Pathogen Omics Research Center
  TITLE     complete genome sequence of Bacillus cereus FORC_047
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5365433)
  AUTHORS   Lee,J.-H., Kim,Y.-T., Ku,H.-J., Kim,H., Kim,H., Choi,S.-H. and
            Ryu,S.
  CONSRTM   Food-borne Pathogen Omics Research Center
  TITLE     Direct Submission
  JOURNAL   Submitted (04-NOV-2016) Food Science and Biotechnology, Kyung Hee
            University, 1732, Deogyeong-daero, Giheung-gu, Yongin, Gyeonggi
            17104, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: PacBio SMRT Analysis v. 2.3.0
            Genome Coverage                   :: 169
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002220285.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:13:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,922
            CDSs (total)                      :: 5,768
            Genes (coding)                    :: 5,607
            CDSs (with protein)               :: 5,607
            Genes (RNA)                       :: 154
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 107
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 161
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 161
            Pseudo Genes (frameshifted)       :: 73 of 161
            Pseudo Genes (incomplete)         :: 89 of 161
            Pseudo Genes (internal stop)      :: 42 of 161
            Pseudo Genes (multiple problems)  :: 36 of 161
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:30:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2415296
            Orig. end                         :: 2440535
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017060.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Food-borne Pathogen Omics
            Research Center.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25239
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="6"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..25239
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25239
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:15239](+)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15239
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            405..965
                     /db_xref="GeneID:72449171"
                     /locus_tag="FORC47_RS12580"
                     /old_locus_tag="FORC47_2337"
     CDS             405..965
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /db_xref="GeneID:72449171"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017656373.1"
                     /locus_tag="FORC47_RS12580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2337"
                     /product="GNAT family protein"
                     /protein_id="WP_048656286.1"
                     /transl_table=11
                     /translation="MENDNQVFWRTDCLVLRRFSMDDTNYFHFYRSNPEVAKFQSWVNY
                     QYHEAKTFVNEQVKNNPNLPGTWFQFAIALAENNKIIGDCALHTLVNEPRIVEIGFTLS
                     PEYQGKGYATEAVCALLNYIFHSLRKHKVIAFSDVRNNKSISVLERVGLRREGHLLQNY
                     MLKGQWIDEYQYSILKSEWNDAT"
     gene            <984..1085
                     /db_xref="GeneID:72449172"
                     /locus_tag="FORC47_RS12585"
                     /pseudo=""
     CDS             <984..1085
                     /codon_start=1
                     /db_xref="GeneID:72449172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002112469.1"
                     /locus_tag="FORC47_RS12585"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="DUF2179 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKELIHEIDENAFVTVYDVAEVQGGNFKKHDIH"
     gene            1482..2324
                     /db_xref="GeneID:72449173"
                     /locus_tag="FORC47_RS12590"
                     /old_locus_tag="FORC47_2338"
     CDS             1482..2324
                     /codon_start=1
                     /db_xref="GeneID:72449173"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002141840.1"
                     /locus_tag="FORC47_RS12590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2338"
                     /product="metallophosphoesterase"
                     /protein_id="WP_053564455.1"
                     /sec_met_domain="Metallophos_2 (E-value: 8.1e-08, bitscore:
                     30.8, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKKIKRSILLIATLVGCSIFLYLQNNLISITEVKITSSKIPSSF
                     KGYKILQISDLHNKKFGDNQDVLIQKIKSIDPDIIAITGDLIDSKSYDAEVSMQLIREI
                     VKKYPVYFVTGNHEQWSGKYNNLEKELKKYDVNVLRNEHVGIRKGEQEINLLGIDDPEF
                     VTGNRDEGNIIIDEIKKAKIEMQPDKYNVLLSHRPEFIKEYTNERLDLVLSGHAHGGQV
                     RLPFIGGLVAPNQGVLPKYTAGLYVEQNTSMVVSRGLGNSIIPQRILNRPEIVVVQLN"
     gene            2540..2791
                     /db_xref="GeneID:72449174"
                     /locus_tag="FORC47_RS12595"
                     /old_locus_tag="FORC47_2339"
     CDS             2540..2791
                     /codon_start=1
                     /db_xref="GeneID:72449174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548597.1"
                     /locus_tag="FORC47_RS12595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2339"
                     /product="hypothetical protein"
                     /protein_id="WP_000548621.1"
                     /transl_table=11
                     /translation="MHKEYEIEEYTAIEEQIHYYCKCLLVSHPDQIIKYLEKRLEKYAE
                     TLQYAHLYPDTVILPLQQLVIEYSLDVARIRKYMNLKT"
     gene            2980..3705
                     /db_xref="GeneID:72449175"
                     /locus_tag="FORC47_RS12600"
                     /old_locus_tag="FORC47_2340"
     CDS             2980..3705
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:72449175"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001187059.1"
                     /locus_tag="FORC47_RS12600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2340"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_089171043.1"
                     /transl_table=11
                     /translation="MQQSSIILRTVSKSFGKKEVLHNLSLQVEKAEIFGFVGPSGSGKT
                     TLIKMIAGINEATKGEVLVNNTNMPNLNEMKRIGYMAQADALYEELSAYENADFIATMY
                     GLKGKSKKTRIAEVFELVQLSQYMKKQVQQFSGGMKKRLSLAIALLHEPEILILDEPTV
                     GIDPLLRKTIWEKFYDLKKKGTTIIVTTHIMDEAEFCERLGLIREGKLVAVGTTEELKK
                     RVSSGRIEDVFLLEEVVSS"
     gene            3702..4721
                     /db_xref="GeneID:72449176"
                     /locus_tag="FORC47_RS12605"
                     /old_locus_tag="FORC47_2341"
     CDS             3702..4721
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:72449176"
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002161721.1"
                     /locus_tag="FORC47_RS12605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2341"
                     /product="ABC transporter permease"
                     /protein_id="WP_089171044.1"
                     /transl_table=11
                     /translation="MRVNGVIIRIIRQFFRDKRSLAMMFGAPMLLLWLLSLVFTQKDYI
                     PQIAVVDMPAQIVKVMKNQEASIYEYSKENAISELEKQKVDAILRIENGKMKLLLEGSD
                     SSKNRAVLQVLQKSTEKNDVSIMKPEVNYLHGSKDFTMFDGLGPVLIGFFTFFFVFILS
                     GVSFVRERLSGTLERLLSTPVRRWEIVAGYIIGFGIFAFIQSIIIVSFSVYILDLYVAG
                     SIWLTLLITCMLSLTALTLGTFLSAYANNEFQMIQFIPLVIVPQIFFSGLFPMESMNKW
                     LQMLGKLFPLTYGADAMRQVMIRNQGFTEIALDLTVLLLFSILFAVGNVFALKKHRKI"
     gene            4746..5399
                     /db_xref="GeneID:72449177"
                     /locus_tag="FORC47_RS12610"
                     /old_locus_tag="FORC47_2342"
     CDS             4746..5399
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:72449177"
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168192.1"
                     /locus_tag="FORC47_RS12610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2342"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_089171045.1"
                     /transl_table=11
                     /translation="MQKDWLEELIAATNTDKRNERQMRILEAAVDMFGEKGYASTSTSE
                     IAKRAGVAEGTIFRYYKTKKDLLLAVVMPTLTKFAAPFFVQTFAKEIFKSEYESYEGLL
                     RVVIHNRFKFAQKHFPMIKILIQEVPFQTELKNEIQQLVETELFSHFKKLIVKFQEEGE
                     IIEIPQSSVLRLTLSAVLGLLLTRFLLLPEEKWDDEMEIENTIQFILYGLTPRI"
     gene            complement(5521..5820)
                     /db_xref="GeneID:72449178"
                     /locus_tag="FORC47_RS12615"
                     /old_locus_tag="FORC47_2343"
     CDS             complement(5521..5820)
                     /codon_start=1
                     /db_xref="GeneID:72449178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728146.1"
                     /locus_tag="FORC47_RS12615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2343"
                     /product="WGxxGxxG family protein"
                     /protein_id="WP_000728156.1"
                     /transl_table=11
                     /translation="MKKKLSSILSVLALSIMFLGTSTQAEYDGNNMNRVNNTDISTRVN
                     DNNLDRVNNDVRTRNVNTTNDLNDNRDKNNNWAWLGLLGLAGLLGLRKRDKETR"
     gene            6054..7022
                     /db_xref="GeneID:72449179"
                     /locus_tag="FORC47_RS12620"
                     /old_locus_tag="FORC47_2344"
     CDS             6054..7022
                     /codon_start=1
                     /db_xref="GeneID:72449179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248633.1"
                     /locus_tag="FORC47_RS12620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2344"
                     /product="DUF523 and DUF1722 domain-containing protein"
                     /protein_id="WP_089171046.1"
                     /transl_table=11
                     /translation="MRQFAKPTIVVSKCLEFDACRYNGEMIPDVTIRNLQPFVTFIPVC
                     PEVEIGLGTPRETIRIVEENGENRLVQPSTREDVTEKMEQFSNDFLQTILDVDGFILKN
                     RSPSCGTRDVKIYSGFEKAPAKGKGAGLFGGAVVKNFSHLPIEEEGRLSNFIIREHFFT
                     RLFTIAYYKMIKQNKNMKELVSFQSDNKYLFMAYNQVKQKELGRIIANQKNEKIEVVFE
                     NYEKTLYELFMRTPRYTSNVNVCEHIFGYFKTKLKKQEKDHFIELLQKYAEKKIPLSSL
                     LTILKSWAIRFDEKYLLRQTYFEPYPEALVEISDSGKGRDY"
     gene            7239..8384
                     /db_xref="GeneID:72449180"
                     /locus_tag="FORC47_RS12625"
                     /old_locus_tag="FORC47_2345"
     CDS             7239..8384
                     /codon_start=1
                     /db_xref="GeneID:72449180"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001980414.1"
                     /locus_tag="FORC47_RS12625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2345"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_000397279.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.8e-39, bitscore:
                     133.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 5.5e-26, bitscore:
                     88.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 7.3e-57, bitscore:
                     190.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFTLTREKQMIKEMVRDFAEKEIAPKAVYYDKTAEFPYETFQKM
                     GELGLLGIPFPEEYGGSGGDTVSYALAVEEIGRACGGTGLSYAATISLGASPIYYFGTE
                     EQKQKYLVPMASGKTLGAFGLTEPNAGSDAGGTQTKAVLDGDEYVISGEKCWITNAEYA
                     NTIIVTAVNGIEENGRKRISAFIVPTTSEGLTISSPYDKMGVRASNTCEIVLDGVRVPK
                     ENILGDVNKGFKQFLYTLDGGRISIAALAVGIAQSAFERALQYAKERQQFGKSISNFQA
                     IQFKLADMATEVELARNLVHKAAWLKDNDKPFGKEAAMAKLFASEAASRIANQAVQIHG
                     GYGYMREYEVERHIRDAKLLEIGEGTSEIQRLVIARHLGCR"
     gene            8400..9737
                     /db_xref="GeneID:72449181"
                     /locus_tag="FORC47_RS12630"
                     /old_locus_tag="FORC47_2346"
     CDS             8400..9737
                     /codon_start=1
                     /db_xref="GeneID:72449181"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000486723.1"
                     /locus_tag="FORC47_RS12630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2346"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_048558513.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 2.1e-10,
                     bitscore: 38.7, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 1.1e-05, bitscore:
                     23.8, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 2.2e-06, bitscore: 25.7,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 5.4e-09, bitscore:
                     34.1, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQKILIANRGEIAVRIMKTCQKLGIRTVAIYSEADENALHVKMA
                     NEAYLVGGPRVQESYLNLEKIIEIAKKTNAEAIHPGYGLLSENPSFPVRCKEEGIVFIG
                     PSEEIITKMGSKIESRIAMQAADVPVVPGITTNIETAEEAIEIAKQIGYPLMLKASAGG
                     GGIGMQLMETEQTLTKAFESNKTRAQNFFGNGEMYLERYIADAHHIEIQLLADTHGNTV
                     YLWERECSVQRRNQKVIEEAPSPFLDEGTRKAMGEVAVQAAKALGYTNAGTVEFLVDNQ
                     KNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLLIASGEKLSFTQDDVKRSGHAIEARIY
                     AEDPKTFFPSPGKITDLTLPSNVRIDHFLENHVTITPFYDPMIAKVIAHGETREEAISK
                     LHDALEELKVEGIKTNTPMLLQVLEDEVFKEGIYTTGFVTKQLVKK"
     gene            9764..9979
                     /db_xref="GeneID:72449182"
                     /locus_tag="FORC47_RS12635"
                     /old_locus_tag="FORC47_2347"
     CDS             9764..9979
                     /codon_start=1
                     /db_xref="GeneID:72449182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001987345.1"
                     /locus_tag="FORC47_RS12635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2347"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="WP_089171047.1"
                     /transl_table=11
                     /translation="MMTKVYASMAGNVWKIVVGVGDTVEEEQDVVILESMKMEIPIISE
                     ETGTVMKINVQEGDFVNEGDVLLEIE"
     gene            10001..10912
                     /db_xref="GeneID:72449183"
                     /gene="mvaB"
                     /locus_tag="FORC47_RS12640"
                     /old_locus_tag="FORC47_2348"
     CDS             10001..10912
                     /EC_number="4.1.3.4"
                     /codon_start=1
                     /db_xref="GeneID:72449183"
                     /gene="mvaB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017149491.1"
                     /locus_tag="FORC47_RS12640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2348"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_089171048.1"
                     /sec_met_domain="HMGL-like (E-value: 1.1e-47, bitscore:
                     161.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPNFAVIKEVGPRDGLQNEKKIVGTKDKVKWIQLLTEAGLSYV
                     EVSSFVHPKWVPALADANDVFSELKRDPNVTYAALVPNQNGLERAFLQNVDEVNVFLSA
                     SESHNKSNINKSIKEALVVIEDITKQALFEGKKVRGYVSTVFGCPYEGDISVTAVDELC
                     NQLFSYGIYEVSLGDTIGVANPLQVEQVLEYLLKKYDASQFAMHFHNTYGMALANVVKS
                     LEYGITTFDSSCGGLGGCPYAPGASGNVATDDLVHMLHKLGVQTNIDEEKLLRASQFIQ
                     SKLNIQLPSHVYRALQHKTISR"
     gene            10917..11705
                     /db_xref="GeneID:72449184"
                     /locus_tag="FORC47_RS12645"
                     /old_locus_tag="FORC47_2349"
     CDS             10917..11705
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (14-254). E-value: 2.4e-74. Score:
                     241.7. Matches aSDomain:
                     nrpspksdomains_FORC47_RS12645_ECH.1"
                     /codon_start=1
                     /db_xref="GeneID:72449184"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001990763.1"
                     /locus_tag="FORC47_RS12645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2349"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_089171049.1"
                     /transl_table=11
                     /translation="MLQLQNISVDYVTPHVVKISLYRERQANSLSLALLDELQTILTQI
                     SEDSNVRVVILTGAGEKAFCAGADLKERADMNEEQVRHAVSMIRTTMEMVEQLPQPVIA
                     AINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKEL
                     IYTGRRISAHEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQV
                     DLHTGLQMEKQAYEGVIHTKDRLEGLQAFKEKRTPTYKGE"
     aSDomain        10959..11678
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FORC47_RS12645_ECH.1"
                     /evalue="2.40E-74"
                     /label="FORC47_RS12645_ECH.1"
                     /locus_tag="FORC47_RS12645"
                     /protein_end="254"
                     /protein_start="14"
                     /score="241.7"
                     /tool="antismash"
                     /translation="HVVKISLYRERQANSLSLALLDELQTILTQISEDSNVRVVILTGA
                     GEKAFCAGADLKERADMNEEQVRHAVSMIRTTMEMVEQLPQPVIAAINGIALGGGTELS
                     LACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAHEAKE
                     YGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYE
                     GVIHTKDRLEGLQAFKEK"
     gene            11708..13249
                     /db_xref="GeneID:72449185"
                     /locus_tag="FORC47_RS12650"
                     /old_locus_tag="FORC47_2350"
     CDS             11708..13249
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:72449185"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389703.2"
                     /locus_tag="FORC47_RS12650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2350"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_000886755.1"
                     /transl_table=11
                     /translation="MLDQKQQSNTFEERVETIKQGGAPKYHEQNKAKGKLFVRDRLALL
                     FDNGEYVEDALFANCEQTGLPADGVVTATGKIHGRTACVMANDSTVKAGSWGSRTVEKI
                     LRIQETAEKLRVPLFYLVDSAGARITDQVEMFPGRRGAGRIFYNQVKLSGKVPQVCLLF
                     GPSAAGGAYIPAFCDVVMMVEGNASMYLGSPRMAEMVIGEKVTLEEMGGARMHCSVSGC
                     GDVLCKTEEDAITQARQYISYFPNNYLEKTPLVTPQEPKQFDKTLEQIIPENQNAPFNM
                     KDLINRVIDEGSFYEVKKLFAQELITGLARIDGKPVGIIANQPRMKGGVLFHDSADKAA
                     KFINLCDAYHIPLLFLADVPGFMIGTKVERAGIIRHGAKMISAMSEATVPKISIVVRKA
                     YGAGLYAMAGPAFEPDCCLALPTASIAVMGPEAAVNAVYANKIAALPEEERASFIAEKR
                     EEYKKDIDIYHLASEMVIDGIVHPNNLREELKGRFEMYMSKYQVFTDRKHPVYPV"
     gene            13299..15239
                     /db_xref="GeneID:72449186"
                     /locus_tag="FORC47_RS12655"
                     /old_locus_tag="FORC47_2351"
     CDS             13299..15239
                     /NRPS_PKS="Domain: AMP-binding (99-521). E-value: 4.1e-81.
                     Score: 264.6. Matches aSDomain:
                     nrpspksdomains_FORC47_RS12655_AMP-binding.1"
                     /codon_start=1
                     /db_xref="GeneID:72449186"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017560287.1"
                     /locus_tag="FORC47_RS12655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2351"
                     /product="AMP-binding protein"
                     /protein_id="WP_089171050.1"
                     /sec_met_domain="AMP-binding (E-value: 7.7e-87, bitscore:
                     289.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQAVWFPTEEYKEKTRLYSWMKSLGYEDYETFYNKSIEETAWLW
                     GEAEKAVGYQWMKPYTEVLDLENGTPFAQWYNGGTCNVVESALSRWLADEETRVQPALQ
                     YEGENGTSKSFTYEELDNWVSLVANGLKHAGIEKGDRVTIYMPMIPETVVAMLAVMKIG
                     AIISPIFSGFASDAVMTRVQAAGSKMIITADGFSRRGKIVSLKDEVDKACEHCPTVEKV
                     VIVRHAGNDFTPHNYDFSWSTLEKEKPFIHAEEMQSDDPLMLIYTSGTTGKPKGTVHTH
                     AGFPLKAAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLLFGSLINGATMVMYEGVPDFPE
                     ADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHSLKSLEVFASTGEPWNPDPWMW
                     LFETVGKGNVPICNYSGGTEISGGIFGNVLIKPIAPISFNASLPGMAAVVLDDQGKPIR
                     DEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKWVHGDWVIYDGEQYIITGRSDD
                     TLNIAGKRIGPAEYESILVKHNDVIEAAAIGVPDEVKGEVCHCFVVLRDHVTFTGELKK
                     ELMSLVNSHIGKALCPKDIHVVEDLPKTRNSKVMRRVIKAAYLGKELGDLSSLVNPEVV
                     PFIQGLQSSKL"
     aSDomain        13596..14861
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FORC47_RS12655_AMP-binding.1"
                     /evalue="4.10E-81"
                     /label="FORC47_RS12655_AMP-binding.1"
                     /locus_tag="FORC47_RS12655"
                     /protein_end="521"
                     /protein_start="99"
                     /score="264.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="QPALQYEGENGTSKSFTYEELDNWVSLVANGLKHAGIEKGDRVTI
                     YMPMIPETVVAMLAVMKIGAIISPIFSGFASDAVMTRVQAAGSKMIITADGFSRRGKIV
                     SLKDEVDKACEHCPTVEKVVIVRHAGNDFTPHNYDFSWSTLEKEKPFIHAEEMQSDDPL
                     MLIYTSGTTGKPKGTVHTHAGFPLKAAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLLFG
                     SLINGATMVMYEGVPDFPEADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHSLK
                     SLEVFASTGEPWNPDPWMWLFETVGKGNVPICNYSGGTEISGGIFGNVLIKPIAPISFN
                     ASLPGMAAVVLDDQGKPIRDEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKWVH
                     GDWVIYDGEQYIITGRSDDTLNI"
     CDS_motif       14085..14141
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FORC47_RS12655_0001"
                     /evalue="7.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="FORC47_RS12655"
                     /protein_end="281"
                     /protein_start="262"
                     /score="24.7"
                     /tool="antismash"
                     /translation="MLIYTSGTTGKPKGTVHTH"
     CDS_motif       14832..14894
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FORC47_RS12655_0002"
                     /evalue="7.80E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="FORC47_RS12655"
                     /protein_end="532"
                     /protein_start="511"
                     /score="12.3"
                     /tool="antismash"
                     /translation="TGRSDDTLNIAGKRIGPAEYE"
     misc_feature    complement(15530..15543)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.67"
                     /tool="antismash"
     misc_feature    15531..15544
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.94"
                     /tool="antismash"
     gene            15566..16920
                     /db_xref="GeneID:72449187"
                     /locus_tag="FORC47_RS12660"
     CDS             join(15566..16019,16019..16920)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:72449187"
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611144.1"
                     /locus_tag="FORC47_RS12660"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS3 family transposase"
                     /protein_id="WP_089171051.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MAKFTSDEKIQIVLRYLNGNESYREIGRSLGINDTIILNWVNQYK
                     QNGLEAFLKRCTNYTQQFKLDVLNFMIENGMSLFETAAIFNIPAPSTISVWKKQLETQG
                     IDALQSKKKGRPSMKKDSNKQLKQPLAEGSVEALEARIKQLEMENEYFKKVKCLSSKQG
                     KITKQDKAQVVYELRHKYSVKALVELATIPRSTYYDLVKKMNRPDVDADLKAEIKAIYE
                     ENEGRYGYRRIRDELTNRGQKVNHKKVQRIMKELGLKCVVRMKKYKSYKGKVGRIAPNI
                     LERNFYTDAPNQKWVTDITEFKLFGEKLYVSPVLDLYNGEIITYTIGSRPTYSLVSDML
                     EKVLERLPETHQLLMHSDQGWHYQMRQYVRTLESRAIVQSMSRKGNCYDNAVIENFFGI
                     MKSEFLYIKEFENVEHFKIELEKYIDYYNTKRIKAKLKMSPVQYRTHFYQAA"
     gene            17023..17238
                     /db_xref="GeneID:72452647"
                     /locus_tag="FORC47_RS31190"
     CDS             17023..17238
                     /codon_start=1
                     /db_xref="GeneID:72452647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237376.1"
                     /locus_tag="FORC47_RS31190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_000236251.1"
                     /transl_table=11
                     /translation="MVIMTLAIVPGESRSEAVTVTVPGPLAARNTAVKLPEALVMTARG
                     TMKARDGLLNEKLTTTPGVGLPFTNT"
     misc_feature    17258..17275
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 23.05"
                     /tool="antismash"
     gene            17284..17568
                     /db_xref="GeneID:72452648"
                     /locus_tag="FORC47_RS31195"
     CDS             17284..17568
                     /codon_start=1
                     /db_xref="GeneID:72452648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254010.1"
                     /locus_tag="FORC47_RS31195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_245912945.1"
                     /transl_table=11
                     /translation="MVSLEVKVIDAGPAGRLNPVGPVGPVGPVDPVGPVGPVDPVDPVD
                     PVDPVDPVGPVDPVDPVDPVGPVNPVGPVGPVDPVNPVAPVEPVGPVGN"
     gene            complement(<17586..17642)
                     /db_xref="GeneID:90069853"
                     /locus_tag="FORC47_RS31535"
                     /pseudo=""
     CDS             complement(<17586..17642)
                     /GO_component="GO:0043592 - exosporium [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:90069853"
                     /inference="COORDINATES: protein motif:HMM:TIGR03720.3"
                     /locus_tag="FORC47_RS31535"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="exosporium leader peptide-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDEFLSFAALNPGSIGPTL"
     gene            complement(17840..18208)
                     /db_xref="GeneID:72449188"
                     /locus_tag="FORC47_RS12670"
                     /old_locus_tag="FORC47_2355"
     CDS             complement(17840..18208)
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:72449188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002189674.1"
                     /locus_tag="FORC47_RS12670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2355"
                     /product="septum formation initiator family protein"
                     /protein_id="WP_089171053.1"
                     /transl_table=11
                     /translation="MGNIPKVSSHQSNPNIPSQQVNPTTQQGSIKKTRRRIITTLAFIL
                     PIIFVLQYSLNNQQEMIKEKQITLNMEQQKLSSVKKDGHSLNKDVKALTSSEEEILKFA
                     RKLYGFSKQNETIFQIAE"
     gene            complement(18599..18937)
                     /db_xref="GeneID:72449189"
                     /locus_tag="FORC47_RS12675"
                     /old_locus_tag="FORC47_2356"
     CDS             complement(18599..18937)
                     /codon_start=1
                     /db_xref="GeneID:72449189"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FORC47_RS12675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FORC47_2356"
                     /product="hypothetical protein"
                     /protein_id="WP_172805521.1"
                     /transl_table=11
                     /translation="MKGGRNKCPGKMIAGVLRKSIVVMIGGNLKKSIIVMMIGVLRKNI
                     VMMIGGNLKKSVIVMMIGVLNEISVIVNVSLFVAIVKEKIGNIFDVNLKERICFLEPIN
                     TRMYYTKS"
     gene            19501..19857
                     /db_xref="GeneID:72449190"
                     /locus_tag="FORC47_RS12680"
                     /old_locus_tag="FORC47_2357"
     CDS             19501..19857
                     /codon_start=1
                     /db_xref="GeneID:72449190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000535569.1"
                     /locus_tag="FORC47_RS12680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2357"
                     /product="hypothetical protein"
                     /protein_id="WP_000535577.1"
                     /transl_table=11
                     /translation="MGSRFNNCKKKCTCKQDDCWEVFEECKKEQHEKCDNSCVQGIRDE
                     LKKLINRTVQINTEGRTYVGTVSSVSCDVVRLAAIPGSVGVIISICKIEAIFPPVTTVT
                     ADFDFNGIDVANKA"
     misc_feature    19872..19887
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.06"
                     /tool="antismash"
     gene            19963..20496
                     /db_xref="GeneID:72449191"
                     /locus_tag="FORC47_RS12685"
                     /old_locus_tag="FORC47_2358"
                     /pseudo=""
     CDS             19963..20496
                     /codon_start=1
                     /db_xref="GeneID:72449191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246375.1"
                     /locus_tag="FORC47_RS12685"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2358"
                     /product="GNAT family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MMYERSMELIKLKTFKKSDFKQLINWINSE"
     gene            complement(20767..21375)
                     /db_xref="GeneID:72449192"
                     /locus_tag="FORC47_RS12690"
                     /old_locus_tag="FORC47_2359"
     CDS             complement(20767..21375)
                     /codon_start=1
                     /db_xref="GeneID:72449192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807974.1"
                     /locus_tag="FORC47_RS12690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2359"
                     /product="hypothetical protein"
                     /protein_id="WP_089171055.1"
                     /transl_table=11
                     /translation="MKEIKVGLTQFLDFTLKGSTAKTTFIKNLKSQPEYQPAFDYWKQL
                     RETVIKFHQNKLPFEYLETLVQTVDQKKKQNYIDVIKQYKKFIKNKDISWFDPGKSHWK
                     SDDLIVRSSPELGLFINNEPHLIKLFFKGKKERIDKYNINSTLTLLNESTFSNERNDVN
                     YTVLNIQKNRMYTNNSINNNHLVALKSEANQFCYIWNNL"
     gene            21512..21634
                     /db_xref="GeneID:72452649"
                     /locus_tag="FORC47_RS31200"
                     /old_locus_tag="FORC47_2360"
     CDS             21512..21634
                     /codon_start=1
                     /db_xref="GeneID:72452649"
                     /inference="COORDINATES: protein motif:HMM:NF021016.4"
                     /locus_tag="FORC47_RS31200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2360"
                     /product="hypothetical protein"
                     /protein_id="WP_245912949.1"
                     /transl_table=11
                     /translation="MDHSIEDKLGNRILPGDRLLIKSDSELILKDNNIDYLAWI"
     misc_feature    21526..21542
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.51"
                     /tool="antismash"
     gene            complement(22087..22224)
                     /db_xref="GeneID:72449193"
                     /locus_tag="FORC47_RS12700"
                     /old_locus_tag="FORC47_2361"
     CDS             complement(22087..22224)
                     /codon_start=1
                     /db_xref="GeneID:72449193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376553.1"
                     /locus_tag="FORC47_RS12700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2361"
                     /product="DUF3956 domain-containing protein"
                     /protein_id="WP_000376554.1"
                     /transl_table=11
                     /translation="MDSCVVFVNGQPFLVLSVAGIEIARLEISLQVALALRVLGIPICD
                     "
     misc_feature    complement(22377..22386)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            <22390..22500
                     /db_xref="GeneID:72449194"
                     /locus_tag="FORC47_RS12705"
                     /pseudo=""
     CDS             <22390..22500
                     /codon_start=1
                     /db_xref="GeneID:72449194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288863.1"
                     /locus_tag="FORC47_RS12705"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="DinB family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="VLRHVIVHEIHHIGQLSIWARELNLQAVSANLIGRG"
     gene            complement(22562..23578)
                     /db_xref="GeneID:72449195"
                     /locus_tag="FORC47_RS12710"
                     /old_locus_tag="FORC47_2362"
     CDS             complement(22562..23578)
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:72449195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160038.1"
                     /locus_tag="FORC47_RS12710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2362"
                     /product="serine hydrolase"
                     /protein_id="WP_089171056.1"
                     /transl_table=11
                     /translation="MQFLKKFAILLLSFFITALIVLYFYLYVNGPIIQAKSAILINANS
                     GEIVYKKNEETPVQSATLSKLMTEYIVLEQLNDRKIQLDDFVQISNEVFRVETSPIQVT
                     SNDKTTVRDLLHVLLLAGNNRSALALAEHIAGTEDNFTILMNKKAKELQLLQPSPFLNS
                     TGINHDTNKQSTTTAIDAAKLAARLVKDFPDVLNITKLTSYQFTFKDSQVFNTNKMIYS
                     LNENIKLQGVDGLQTSFSTNGNYSFVSTAKLGDTRLISVILDADEENISFIETKKLLQY
                     GFDPSSYSALQAFKDTLTSWTILLQFKNLIIQTIMIFLIITTLMFLHIRQKKSEDFN"
     gene            complement(23754..24911)
                     /db_xref="GeneID:72449196"
                     /locus_tag="FORC47_RS12715"
                     /old_locus_tag="FORC47_2363"
     CDS             complement(23754..24911)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:72449196"
                     /gene_functions="resistance (resist) vanS"
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016129473.1"
                     /locus_tag="FORC47_RS12715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FORC47_2363"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_001243312.1"
                     /transl_table=11
                     /translation="MRNEAFDILKDIPKWKLIFWLLLAITLTPITELIIYRLVTSVIES
                     SLTLTELGKEFIRIFGYEKYKGIKESLWMMIVSYLFLFSIFSSYLYIFYRHEKKLYYET
                     CIKKMIEEIRYIANGNFNHKVSIVNHNYLEELAIGVNEIVEQLKVSIDEERQAEQAKSE
                     LITNVSHDLRTPLTSIVGYVNLIHHDNYRDEVELRYYIQVIYDKVTRLNALMNDLFEYT
                     RVQNKELSLYSVPIDIVELLGQLTVQFRIQVQEANIECRPSFPSQKLMVLADGDKLVRV
                     FENLIINAIAYGSEGRYIDLTAYESNNMITIDITNYGQPIPSTDLPHIFERFYRVEKSR
                     STNTGGSGLGLAIAKSIVELHKGTIEVYSDDEKTTFTVKLLPYKC"
ORIGIN
        1 acagagtgga tgaaaggaaa tgctacaggg gacaaactta ttcgtgcagg cgtaccaact
       61 gactgggtag ttggagataa atcaggtgct ggcagttacg ggacaagaaa tgatattgct
      121 atcgtttggc ctccgaatag agcaccaatt atcatcgcaa ttttatctag taaagatgag
      181 aaagaggcta gctatgataa tcaactcatt gcagaggcaa cggaagttat agttaaggct
      241 cttaagtaat aatctttcaa ttctttatgt aatataatta aaaataagga cttggaaagc
      301 gattcttttt aatgtgaaaa gaatcgcttt tttataagca tgtaaactat ttatacctat
      361 gtattataaa gatataatta atgtagaaaa gagggtgaat agttatggag aatgacaatc
      421 aagtcttttg gagaacagat tgtcttgttt tgagaaggtt tagtatggat gacactaact
      481 actttcattt ttatcgttct aatccagaag tggctaaatt tcagtcatgg gttaattatc
      541 aatatcatga ggctaaaacg tttgtaaatg aacaagttaa aaataatcct aatctaccag
      601 gtacttggtt ccagttcgca attgctttgg ctgaaaataa caaaataatt ggagattgtg
      661 cacttcacac acttgtaaat gaacctcgca tcgtagaaat tggatttact ctttctccag
      721 aatatcaggg gaaaggctat gcaactgaag ctgtttgtgc cttactgaat tacatatttc
      781 attcattacg gaaacataaa gtgattgcat tttcggacgt tcgaaataat aagtctattt
      841 ctgtactaga acgagtgggg ttgaggagag aaggtcattt attacagaat tacatgctaa
      901 aagggcagtg gattgatgaa tatcaatatt caatattgaa gtctgaatgg aatgacgcta
      961 cataatttta aaatttagaa acaatgaagg aacttattca tgaaattgat gaaaatgcct
     1021 ttgtcactgt atatgatgtt gcggaagtac aaggcggaaa ctttaaaaag catgatattc
     1081 attaagggta ttaactaagt taaatgtttt atacatagtt gattattgaa aaagataaaa
     1141 aactcaccac atatagagag acaactggta tgtgctaaga tgtacaacgg caagatacat
     1201 agaactaaaa ctaagatatt catacgaact caaaaagctg aaattcctta acttgggaat
     1261 ttcggcttta atgttatatg atagagttac gattagaaca gaaccgggca tgtttacttc
     1321 aacagagtga tataagttct tcagttccta aaattagaaa cttgtacttg attatcgtag
     1381 ttaaatcgat ttcactttaa aagagaaccg ttagataaaa agaataatct attgaaatgt
     1441 ttttgagaat tgtagtattg atgaagattt taggagggaa tatgagcaag aagattaaaa
     1501 gaagtatatt acttattgct acattagtag gttgtagtat ctttttatat ttacagaaca
     1561 atttaataag tataactgag gttaaaataa cctctagtaa aataccatcc tcttttaaag
     1621 ggtataaaat tctacaaatt tcagacttac acaataaaaa atttggcgat aatcaagatg
     1681 tgttaattca aaaaataaaa agtatagacc cagatattat tgcgattacg ggtgatttaa
     1741 ttgacagtaa atcatacgat gcagaagtta gcatgcaatt aatacgagaa attgtaaaga
     1801 aatatcctgt atattttgtg acaggaaacc atgaacaatg gtctggaaag tataacaatt
     1861 tagaaaaaga gttgaagaaa tatgatgtca atgttttaag gaatgaacat gtaggcattc
     1921 gaaagggtga gcaagaaata aacttgctag gtattgatga tccagagttt gttactggaa
     1981 accgtgatga aggaaatatt ataatagatg aaattaaaaa agcgaaaatt gaaatgcagc
     2041 cagataaata taatgtatta ttatcccatc ggcctgaatt tataaaggaa tatacgaatg
     2101 agaggttgga tttggtttta tcgggacatg ctcatggagg gcaagttaga ttgccattta
     2161 tcggaggatt agttgcgcca aatcaaggtg ttttacctaa atatacagcg ggtttatatg
     2221 tagaacaaaa tacatcaatg gtagtgagta gaggattagg aaatagtatc attccgcaaa
     2281 ggattttgaa taggccagaa attgtagtcg tgcagctaaa ttaagctgta cgattttttt
     2341 tatacaaaaa tgagtaaagg ggctttctgt attttgcagg agtaaacatt acaattttgt
     2401 taaaaatttt ctacgttaca taaagtaaca aaatttgacc ctcagtgttt gttatagtgt
     2461 aaataatcaa aaaacttaaa atttgtcgag tgaaaattgt gataagtaat tcatataaaa
     2521 aacttaaagg ggtgtacaca tgcataaaga atatgaaatt gaagaataca cggcgattga
     2581 ggaacaaatc cattattatt gtaaatgttt attagtaagt catcctgatc aaataataaa
     2641 gtatttagaa aaaaggttag aaaaatatgc agaaacatta caatatgcac atttatatcc
     2701 tgacacagtt attttaccgt tacagcaatt agttatcgaa tattctttag acgttgctag
     2761 aattcggaag tatatgaatt taaaaacgta aagtgaaatt tatagtttaa atgaaacaga
     2821 gtcgacttta ggaaatgaaa ttctaatgtc gactctgttt cattgtttaa tatcggtgat
     2881 tgaacataca tactaatcaa cgaagtttga catataatta agcaagagta aaataaaagt
     2941 gagtactcac tcatttttat tggaaaagga ggatgaaacg tgcaacaatc ttcaattatt
     3001 ttacggactg tatcaaaaag ttttggaaaa aaagaagtgt tacacaatct ttcattgcaa
     3061 gttgaaaaag cagagatttt tggttttgtt ggaccttctg gatcggggaa aacaacgctc
     3121 attaaaatga ttgcaggtat taatgaggca acgaaaggtg aagtgcttgt taataatact
     3181 aatatgccta atttaaatga aatgaaacga attggttata tggcccaggc ggatgcatta
     3241 tatgaagaat tgtcagcata tgaaaatgca gattttatag caacgatgta tggattaaag
     3301 ggaaaaagta aaaagacaag aattgcagag gtttttgaac ttgtacaatt gtcacagtat
     3361 atgaaaaagc aagtacaaca attttcaggt ggaatgaaaa aacgcttatc attagcaata
     3421 gcactcctcc atgaaccaga aatattaatt ttagatgagc ctacagtggg gatagatccg
     3481 cttcttagga aaacgatttg ggaaaaattt tatgatctta aaaagaaagg cacaacgatt
     3541 attgtaacga cgcacattat ggatgaagct gaattttgtg agcgtctagg attaattaga
     3601 gaagggaaac tagttgcggt tggaacaact gaagaattga aaaaacgcgt gtcatctgga
     3661 cggattgaag atgtcttttt gttggaagag gtggtgtcat catgagagtt aatggtgtaa
     3721 tcattcgtat tattcgccaa ttttttcgag ataagcgttc gttagcgatg atgtttgggg
     3781 caccaatgtt attactttgg ctattatcgc tagtgtttac acaaaaagac tatataccgc
     3841 aaattgctgt tgttgatatg cccgctcaaa tagtaaaagt gatgaaaaat caagaagcgt
     3901 caatttatga atacagtaaa gaaaacgcga tttctgagtt agaaaaacaa aaggtagatg
     3961 caatacttcg aatagagaat ggaaaaatga aacttctgtt ggaaggtagt gattcgtcaa
     4021 aaaatcgtgc tgtacttcaa gtattgcaaa aaagcacaga gaagaatgat gtatcgatta
     4081 tgaaacctga agtaaattat ttacatggct ctaaagactt tacgatgttt gatgggcttg
     4141 gtcctgtatt aattggtttc tttacatttt tctttgtatt tatattatca ggtgtatcct
     4201 tcgtaagaga acgtttaagt ggtacgctag aaaggttatt atccacccca gtaagaagat
     4261 gggaaatagt cgcaggttat attattggtt ttggaatctt tgcctttata caatccatta
     4321 ttatcgtaag tttttccgtt tatattttag atttatatgt agctggctct atatggctaa
     4381 cgctacttat tacatgtatg ctctctttaa ctgcactaac attaggtacg tttttatcgg
     4441 catacgcaaa taatgaattt caaatgattc aatttatacc gcttgttatt gtgccacaaa
     4501 tcttcttttc tggattgttt ccaatggaat ctatgaacaa gtggctacaa atgttaggga
     4561 aattatttcc gctcacatac ggcgctgacg caatgagaca agtgatgatt cggaatcaag
     4621 ggtttacaga gattgcatta gatcttactg tattattact tttttcaata ttatttgcag
     4681 taggaaatgt atttgcttta aagaaacatc gcaaaatata ataatgacaa aaaggagctt
     4741 tataaatgca gaaggattgg ctggaggaat taatagctgc aactaatacg gataaacgaa
     4801 atgaacgtca aatgcgaata ttagaggcgg ctgttgatat gtttggagaa aaaggatacg
     4861 cttcaacttc aacaagtgaa attgcaaaac gggctggtgt agcggaagga acaatcttcc
     4921 gctactataa gacgaaaaaa gatttattac tagcggtcgt aatgccaact ttaactaagt
     4981 tcgctgcacc attttttgta caaacctttg caaaagaaat atttaaatcg gagtatgaat
     5041 catacgaagg acttttaagg gttgtaattc ataataggtt taaatttgct caaaaacact
     5101 ttcctatgat aaaaatatta attcaagagg tgccattcca aacagaacta aaaaatgaaa
     5161 tacagcaatt agtagaaaca gaactgtttt cacatttcaa aaagttgatt gtgaaatttc
     5221 aagaagaagg ggaaattatt gagataccac aatcttccgt actacgtctt actttatcag
     5281 ctgtattagg tttactctta acaagatttt tattattgcc tgaagaaaaa tgggatgatg
     5341 aaatggaaat tgaaaatacg attcaattta tattgtatgg attaactcca cgaatttaat
     5401 cgtcgaagtg tgaattacat acattacttt taagtaaaaa taaatcgcct ttaaaaaggc
     5461 gatttatttt cattatatat ttttgataaa taagtacttg tttactaaaa atattctaaa
     5521 tcagcgtgtt tctttgtctc tttttctaag acctaataat cctgctagtc ctaataaacc
     5581 aagccaagcc caattattat ttttatcacg attatcattt aaatcatttg ttgtatttac
     5641 atttcgagtt cttacatcat tattaactct gtctaagtta ttgtcattta ctcgagttga
     5701 aatatcagtg ttattaactc tattcatatt atttccatcg tattcagctt gcgtagatgt
     5761 acctaaaaac ataatagata gtgctaaaac acttaaaata gatgataatt tctttttcat
     5821 aacaatccct cctttcttaa tcattaattt ctccgaagca tgtgtgtatt attcatttca
     5881 caatatctaa accctcatta atcgggcgca catttataga aaatagagtt gaatgattgt
     5941 taatatatca ttggatatat atttctcata aaaataaatg aatcaaactt tgcttaaaat
     6001 gttaatatta gtacaattta tattatacgg actagtaata aggaggtaat aagatgcgac
     6061 aatttgcaaa acctacaatc gtcgtaagta aatgtttaga atttgatgct tgtcgttata
     6121 atggagagat gattccagat gtaacaatac gaaatttgca gccatttgtt acatttatac
     6181 ctgtttgtcc agaagtcgag attggattgg ggactcctcg tgaaacgata cgaattgtag
     6241 aagaaaatgg tgagaataga cttgtgcaac cgtcgacacg agaagatgta actgaaaaaa
     6301 tggagcagtt ttcaaatgac tttttacaaa cgatattgga tgtggatggt tttattttaa
     6361 agaatcgttc accaagttgt ggtacgcgtg atgtgaaaat ttattctggt tttgaaaaag
     6421 cgccagcaaa gggaaaagga gctggcttat ttggcggagc agtagtaaaa aatttttcgc
     6481 atcttcctat tgaagaggaa ggtagattgt cgaattttat tattagagag catttcttta
     6541 caaggctatt tacaatcgca tattacaaaa tgattaaaca aaataaaaat atgaaagaac
     6601 ttgtatcgtt tcagtcggat aataaatatt tatttatggc atataatcag gtgaaacaaa
     6661 aggaattagg tcgtataatt gcaaatcaaa aaaatgaaaa gattgaagtg gtatttgaaa
     6721 actatgagaa gactttatat gaattattta tgcgtacgcc ccgttataca tcgaatgtaa
     6781 atgtatgcga gcacattttt ggatatttta aaacaaagtt aaaaaaacaa gaaaaagatc
     6841 attttataga actgttacaa aagtatgcag aaaagaaaat accacttagt agtttactta
     6901 caattttaaa atcatgggct attcgatttg atgaaaagta tttattaaga caaacatatt
     6961 tcgaaccata ccctgaagca ttagtagaaa tttctgattc cggaaaaggt agagattatt
     7021 aaacaataaa ttacataatt cgacacaaaa cctcctatgt tgttgtagaa caatgtagga
     7081 atttttttgt gcattagtac agaatctgtt ttaaaattaa gttatgacag aattgtagca
     7141 attgtctaac taatattctt gtcttttaag ttgttatgtt tgtagtagaa actcgcacgc
     7201 tgtcgaaact caatattcga taaggggtgt gtagcggaat ggaatttact ctaactcgcg
     7261 aaaaacaaat gattaaagaa atggtacgtg actttgctga aaaggaaatc gcaccgaaag
     7321 ctgtatatta tgacaaaact gcagagtttc catatgaaac atttcaaaaa atgggcgaac
     7381 taggattatt aggcatccca ttcccagaag agtatggagg ttcaggtggc gatacggtat
     7441 cgtatgcgtt agcagttgaa gaaattggtc gcgcttgtgg tggcaccggt ttaagctatg
     7501 ctgcaacaat ttcattaggt gcttctccaa tttattattt cggtacagaa gaacaaaaac
     7561 aaaagtattt agttccaatg gcgtcaggta aaacattagg tgccttcgga ttaacggagc
     7621 cgaatgctgg atctgatgca ggtggcactc aaacgaaagc ggtattagat ggtgatgagt
     7681 atgtaatcag tggtgagaag tgttggatta caaacgcaga gtatgcaaat acaattattg
     7741 taaccgctgt caacggtatt gaagagaatg gtagaaaacg tatttctgca tttatcgtgc
     7801 ctactacgag tgaaggatta acgatttcaa gtccttacga taagatgggt gttcgcgctt
     7861 ctaatacttg tgaaatcgta cttgatggtg ttcgtgtacc gaaagaaaat attcttggtg
     7921 atgtaaataa aggctttaaa caatttttat atacacttga tggagggcgt atttcaatcg
     7981 ctgcattggc agttggcatt gcgcaatcag cctttgaacg tgcattacaa tatgcgaaag
     8041 aacgtcaaca atttggaaag tcaatctcta atttccaagc gattcaattt aaattagctg
     8101 atatggcgac tgaagtagag ctagcacgca atttagtaca taaagcagct tggttaaaag
     8161 ataacgataa acctttcggc aaagaagcgg caatggcaaa actatttgca tcggaagcag
     8221 caagccgtat tgcgaatcaa gcagtacaga ttcatggtgg atatggttat atgcgtgaat
     8281 atgaagttga acgacatatt cgtgatgcga aactattaga aattggtgaa ggaacttctg
     8341 aaattcaacg tctcgtaatt gctagacatt taggatgtag ataaaaggga ggaatcacta
     8401 tgtttcaaaa aatattaatt gcgaatcgcg gggaaattgc tgttcgtatt atgaaaactt
     8461 gtcaaaaact tggcatacgc actgttgcta tttattctga agcagatgaa aatgcccttc
     8521 atgtgaagat ggcaaatgaa gcttacttag taggtggacc gcgtgttcaa gaaagttatt
     8581 taaaccttga aaaaattatt gaaatagcta agaagacaaa tgcagaagcg attcatccgg
     8641 gttatggttt attatcagag aatccgtctt ttccggttcg ttgcaaagaa gaaggaatcg
     8701 tatttatcgg tccttcagaa gaaatcatta cgaagatggg aagtaaaatc gaatcacgta
     8761 tcgcaatgca agcagcagat gtcccagtag tcccaggtat tactacaaat attgaaactg
     8821 ctgaagaagc aattgaaatt gcaaaacaaa ttggttatcc cttaatgctt aaggcatccg
     8881 caggcggcgg aggcattggt atgcagttga tggaaactga gcaaacgctc accaaagcgt
     8941 ttgaaagtaa taaaacaaga gcgcaaaact tctttggtaa cggagaaatg tatttagagc
     9001 gatatatagc agatgcgcat catattgaaa ttcagctttt agcagataca catggtaaca
     9061 cagtgtattt atgggagcgt gaatgttcgg tacagcgccg aaatcaaaaa gtaatcgaag
     9121 aagcaccttc accattttta gatgaaggta cacgaaaggc gatgggagaa gttgctgtac
     9181 aagctgccaa agcacttggc tatacaaatg caggtacagt tgagtttctt gtagataatc
     9241 agaagaactt ctatttctta gagatgaata cgagattaca agtagagcat ccagtgacag
     9301 aagaaattac gggattagac cttgtagaac agcaactcct tatcgcaagt ggagagaaac
     9361 tatcatttac tcaggatgat gtaaaacgta gtggtcatgc cattgaagct cgtatttatg
     9421 cagaggatcc gaaaacattc ttcccatcac ctgggaaaat tacagattta acattaccgt
     9481 caaatgtacg gattgatcac ttcttagaaa atcatgtaac gattacacct ttctatgatc
     9541 caatgattgc gaaagtcatt gcacatggcg agactcgtga agaagcaatt tcgaaattac
     9601 atgatgctct agaagaatta aaagtagaag gtattaaaac gaacacgcca atgctactgc
     9661 aagttttgga agacgaagtg ttcaaagagg gtatttatac aacgggtttt gtaacgaaac
     9721 aactcgttaa aaaataagat ttaacaatat taagggggaa aaaatgatga cgaaagtata
     9781 cgcatcgatg gcaggaaacg tttggaagat tgttgtagga gtaggagata cagtagagga
     9841 agagcaggat gtcgtcattt tggaatctat gaaaatggaa attccaatca tttcagaaga
     9901 aactggcaca gttatgaaaa ttaatgtgca agaaggcgat tttgtaaatg aaggagatgt
     9961 attattagaa attgaatagg gagatatagg gggaagcgaa ttgaaactac ctaattttgc
    10021 tgtcattaaa gaagtcgggc cacgtgatgg cttacaaaat gaaaaaaaga ttgttggcac
    10081 aaaagataaa gtaaaatgga ttcaactact tacagaagca ggattgtcgt atgttgaagt
    10141 ttcctcattc gttcacccaa aatgggtccc tgcattagca gatgcaaatg atgtattttc
    10201 tgagctgaaa agggatccaa atgttacata tgctgcgctt gttccgaatc aaaatggttt
    10261 ggaacgagct tttttgcaaa atgtagatga ggtgaatgtt tttttatcag caagtgaatc
    10321 tcataataaa agtaatatta ataaatcgat taaagaagca ttagttgtaa ttgaagatat
    10381 aacaaaacag gcattattcg aagggaaaaa ggtaagaggc tatgtttcta ctgtatttgg
    10441 atgtccttat gaaggggata taagtgttac agcagttgac gaattatgta atcaactatt
    10501 ttcatacggc atttatgaag tttctcttgg ggatacaatc ggtgtagcga atccattaca
    10561 agtagaacaa gtattagaat atctattaaa gaagtatgat gcttcgcagt ttgcaatgca
    10621 ttttcataat acgtatggaa tggctctagc gaatgtagtt aaatcattag aatacggtat
    10681 tacaacgttt gatagttctt gtggtggact cgggggctgc ccttatgcac caggagcatc
    10741 aggtaatgtt gctactgatg acctagtaca tatgctccat aagttaggag tccaaacgaa
    10801 tattgatgaa gagaagttat tgagagcaag tcaatttatt caaagtaaat taaatatcca
    10861 attaccgagt catgtgtata gagcgcttca acataaaacg ataagtaggt gagaagatgc
    10921 tacaattaca aaacatttca gttgattatg taacacctca cgttgtaaag atttcgttat
    10981 atcgtgaaag acaagcaaac tcattatctt tagcattatt agatgaatta caaactatat
    11041 taactcaaat aagtgaagat tcaaacgtgc gtgtagttat tttgactggt gctggtgaaa
    11101 aagcattttg tgctggtgca gatttaaaag agcgtgccga tatgaatgaa gaacaagttc
    11161 gccatgctgt tagtatgatt cgcactacta tggagatggt tgaacaatta ccacagccag
    11221 ttattgctgc tataaatgga atcgcacttg gtggtggtac ggaattaagt ttagcttgtg
    11281 attttagaat tgctgctgaa tctgcaagtc ttggtcttac tgaaacgaca cttgcaatta
    11341 taccaggagc gggtggtaca cagcgcttac cgagattaat tggtgttggt agagcgaaag
    11401 aattaattta tacaggtaga cgtatttcag cgcatgaagc aaaagaatat ggtttagtag
    11461 aatttgttgt accagctaat ttacttgaag agaaagcgat tgaaatagca gagaaaattg
    11521 ctagtaatgg acctattgct gttcgattag caaaagaagc gatttcaaac ggtattcaag
    11581 ttgatttaca taccggatta caaatggaaa aacaagcgta tgagggtgta atccatacga
    11641 aagatagatt agaaggatta caagcattca aggaaaaacg cacaccaacg tataaggggg
    11701 agtaaatatg ttagatcaaa aacaacaatc aaatacattt gaagaacgag ttgaaacgat
    11761 taaacaaggc ggcgcaccaa aatatcatga acaaaataaa gcaaaaggaa aattatttgt
    11821 tcgagatcgt ttagcgcttc tatttgataa tggcgaatat gtagaagatg cattatttgc
    11881 taactgtgaa caaacaggct tacctgcgga cggcgttgta acggcaacgg gtaaaataca
    11941 tggtcgtact gcatgtgtaa tggccaatga ttctactgta aaagctggat cgtggggatc
    12001 acgcacagtt gaaaagattt tacgtattca agaaacagct gaaaaactac gtgttccgtt
    12061 attttattta gtcgactctg ctggagcgcg tattacagat caagtagaaa tgttcccagg
    12121 gcgccgtggt gcaggaagaa tcttctataa tcaagtgaaa ttatcaggta aagttcctca
    12181 agtatgctta ttatttggac cttctgcagc tggtggtgcc tatattccag ccttttgcga
    12241 cgttgtaatg atggtagaag gaaatgcatc tatgtattta ggatctcctc gtatggctga
    12301 gatggttatc ggtgagaagg taactttaga agagatgggc ggagctcgta tgcattgctc
    12361 tgtatcagga tgcggagatg ttttatgtaa gacagaagaa gatgcgatta cacaagcaag
    12421 acaatacatt tcatattttc caaataacta cttagaaaag actccattgg ttacacctca
    12481 agaaccgaaa caattcgata aaacgttaga acaaatcatt ccagaaaatc aaaatgctcc
    12541 tttcaatatg aaagatctca ttaatagagt tattgatgaa ggttcattct atgaagtaaa
    12601 aaaattattt gctcaagagc taattacagg cttagcacgt attgatggta agccagttgg
    12661 tattattgca aatcagccgc gtatgaaggg cggcgtatta ttccatgatt cagctgataa
    12721 agctgctaag tttattaatt tatgcgacgc atatcatatt ccattattat tccttgcgga
    12781 tgtaccagga tttatgatcg gtacaaaagt agagcgtgct ggtattattc gccacggtgc
    12841 aaaaatgatt tctgcaatga gtgaagcaac tgtaccgaag atttctatcg ttgttcgtaa
    12901 agcatatggt gctggtttat atgcgatggc aggtccagca tttgaaccag attgctgcct
    12961 ggcattaccg acagcctcta ttgcggtaat gggtccagaa gctgcggtca atgctgtata
    13021 tgcaaataaa attgcagctt taccagaaga agagcgtgct agctttattg ctgaaaaacg
    13081 tgaagagtat aagaaagata ttgatatata ccacttagca tcagagatgg tgattgatgg
    13141 tattgttcat ccaaacaatt tacgtgaaga gttaaaagga cgtttcgaaa tgtatatgag
    13201 taaatatcaa gtattcacgg atcgtaaaca tcctgtatat ccagtttaaa agccctattt
    13261 agggctttct tgctcaaaaa gttaaggagg ggaaaatatt gaaacaagca gtttggtttc
    13321 caacagaaga gtacaaggaa aaaacacgtt tatatagttg gatgaaatca ttgggatatg
    13381 aagactatga aactttttat aataaatcta ttgaggaaac agcttggctt tggggagagg
    13441 cagaaaaagc agttggctat caatggatga aaccttatac agaagtgtta gatttagaaa
    13501 atggtacacc gtttgcacag tggtataatg gtggaacatg taacgttgta gaatcagctt
    13561 tatcccgctg gcttgcggat gaagagacga gagtacagcc agcacttcag tacgaagggg
    13621 aaaatggaac ttcaaaatca tttacatatg aagagcttga taactgggta agccttgttg
    13681 ccaatggttt gaaacacgcg ggtattgaaa aaggtgaccg tgtaacaatt tatatgccga
    13741 tgattccaga aacagttgtt gcgatgctag ctgtaatgaa aattggagca attatttcac
    13801 caatattctc aggctttgcg tctgatgcag ttatgacacg tgtgcaagcg gcgggttcaa
    13861 aaatgattat tactgcagat ggattttcac gccgcggtaa aattgtttct ttaaaagatg
    13921 aagtagataa agcttgtgaa cattgcccaa ctgttgaaaa agttgttatc gttcgtcatg
    13981 caggaaatga ttttacacca cataactatg acttttcgtg gagtacgcta gaaaaagaaa
    14041 aaccattcat acatgccgag gaaatgcaaa gtgatgatcc attaatgctc atttatacat
    14101 caggaacgac tggtaagccg aaaggaacag tacacacgca tgcaggattt cctttgaaag
    14161 cagcttttga tgcaggattt ggaatgaata ttaaacaagg tgatcgtgta ttatgggtaa
    14221 ctgatatggg ctggatgatg gggccgtttc tattattcgg ttcactcatt aatggagcaa
    14281 cgatggttat gtacgaaggt gttccagact tcccagaagc agaccggtta tgggagacag
    14341 ttgataaata tgaaattact catctaggta tttcgccaac gttaatccga gcattaatgg
    14401 caaaaggtga tgagtatgtc aataaacatt ctttaaagag tttggaagta ttcgcatcaa
    14461 caggagaacc ttggaatcct gatccatgga tgtggctgtt tgaaacagtt ggaaaaggaa
    14521 atgttccaat ctgtaactac tcaggtggaa ctgaaatctc tggtgggatt ttcggtaatg
    14581 ttcttattaa gccaatcgca ccgattagtt ttaacgcatc tttaccagga atggcagctg
    14641 tcgtgctgga tgatcaaggt aaaccaattc gagatgaagt cggagaatta tgcttagaga
    14701 aaccttgggt aggtatgacg aaaagcttct gggaagatga tgaacgttac gtgaacacat
    14761 attggtcgcg ttttgaaaat aaatgggtcc acggtgactg ggtcatttac gatggtgaac
    14821 aatatatcat cacagggcgt tcagacgata cgttaaatat tgcaggtaaa cgtattggac
    14881 ctgctgaata tgaatctatt cttgtgaaac ataatgatgt aatcgaagct gctgcaattg
    14941 gtgtacctga cgaagtaaaa ggtgaagttt gtcattgttt tgtagtgtta agagatcatg
    15001 taacattcac aggagaatta aagaaagaat taatgagttt agtaaactct catattggaa
    15061 aagcgttgtg tcctaaagac atccacgttg tagaagattt accgaaaaca cgtaattcta
    15121 aagtaatgcg ccgtgttatt aaagcagctt acttaggaaa agaattaggt gatttatcat
    15181 cgcttgtaaa tcctgaagta gttccgttta ttcaggggtt acagtctagt aaattataaa
    15241 gttagcaagg agttctatat aaatagagct ccttttttat gtttataaaa agagaagaag
    15301 tgaagttgat gaagaagaaa aattctacta ttggtgttaa gtatgtctgt tttataattt
    15361 ttattaaaat acgatactgt ggcatcttta ttcattggag taattaaatt ttattaagga
    15421 tgaaattcaa taaaagcgtt attttaatag attgttacga aatttaattt gaaaggcaca
    15481 tccaaatgat aaaaaaagag cactataaaa ttgaactgca ccccaattgt tagacacagt
    15541 ctaacaattg gggtgcagtt tttctatggc taaatttaca tctgatgaaa aaatacaaat
    15601 cgttctacgt tatttgaacg gaaatgaaag ttatcgagaa ataggtagat cgctcggtat
    15661 aaatgacaca atcattttga attgggtaaa ccaatataaa cagaatggtc tggaagcttt
    15721 tctaaaacga tgtacaaatt acacacaaca atttaaacta gacgtactaa actttatgat
    15781 tgaaaacggt atgtccttat ttgagacggc agctatcttt aatattcctg ccccttcaac
    15841 gatttctgtt tggaaaaaac agctcgaaac acaaggaatt gatgcccttc aatctaagaa
    15901 aaaggggcgt ccatccatga aaaaagattc aaataaacaa ttaaaacaac ctttagctga
    15961 agggtcagtc gaagcacttg aagcacgcat taaacagctt gagatggaaa atgagtactt
    16021 aaaaaagtta aatgccttag ttcaaaacaa ggaaaaatca caaaacaaga caaagcgcaa
    16081 gtagtctacg aattaaggca taaatattcg gtgaaggcac tcgtggagct agctactatt
    16141 cctcgaagca catattatga tttagtaaag aaaatgaatc gtccagatgt agatgccgat
    16201 ttgaaagctg agattaaagc gatttatgag gaaaatgaag gtcgttatgg ttaccgtcgc
    16261 attcgtgatg aattaacgaa tcgtggccag aaagtgaacc acaagaaggt tcagcgcatt
    16321 atgaaagagc ttgggttaaa gtgtgttgtg cgtatgaaga aatataaatc ctataaagga
    16381 aaagtcggta gaattgcacc taatatttta gagcgtaatt tttatacaga tgcaccgaat
    16441 caaaagtggg taacagacat cacggagttt aaattgtttg gagaaaaact gtatgtatca
    16501 cctgtattag atttatataa tggtgaaatt attacctata caattggttc tagaccgacg
    16561 tattcgcttg tttcagacat gttagagaaa gtattggaac gtttacctga aacccaccag
    16621 ctactgatgc attcggatca aggatggcat tatcaaatga gacagtacgt ccgtacactt
    16681 gaatcaagag ctatcgtcca gagtatgtct cgaaaaggca actgttacga caacgcagta
    16741 atagaaaatt tctttgggat tatgaagtcg gagttcctct acataaaaga atttgaaaat
    16801 gtagagcact ttaaaataga attagaaaaa tatatagatt attataatac gaaacggatt
    16861 aaggcaaaat taaaaatgag cccggtacaa taccggactc atttttatca agctgcctaa
    16921 tgaaataacc gtgtctaact tttaggggtc acttcaaatc agtgctcttt ttattagaaa
    16981 ttgcctagtt cttaaaaata aaattattac ggacaattca caatggtaat aatgacgcta
    17041 gccattgttc caggagaatc aagaagtgaa gcagtaacgg ttactgttcc aggcccatta
    17101 gcggctagaa atacagcggt aaagttacct gaggcattgg taatgacagc aagaggaacc
    17161 atgaaagcaa gagatgggtt actaaatgaa aaactgacca ctacccctgg agtaggacta
    17221 ccgtttacta atacttgacc cgaaaaaaat aaagtattat ttccttgagt ggatacacat
    17281 gctgtggttt cgttagaagt caaggtaata gatgcaggtc cagcaggaag attaaatcca
    17341 gttggcccag ttggcccagt tggcccagtt gatccggttg gtccggttgg tccggttgat
    17401 ccagttgatc cagttgatcc agttgatcca gttgatccag ttggtccggt tgatccagtt
    17461 gatccggttg atccagttgg tccggttaat ccggttggcc cagtcggtcc agttgatccg
    17521 gttaatccag tagctcctgt agaaccggtg ggaccggtag ggaattgaaa aggttgaaca
    17581 ggtggaagtg taggtccaat agaacccgga ttaagtgcag caaaagataa aaactcgtcc
    17641 attatttatc acctctaaaa atcgtattac taatagtaaa tgtaatgata gagcaaagtg
    17701 aaacagacaa gcggttgtat tttaacaaat taaacaaagt agttatatga tagaaagaga
    17761 gattagtatg attcctttag aaattaaata taaaaaggcg attatcttca aatcgccttt
    17821 taggtaatgc cgtgtaattt tattcagcta tttgaaatat agtttcattt tgtttggaaa
    17881 atccatacag tttccttgcg aattttaaaa tttcttcttc actacttgtt aaagccttga
    17941 catccttgtt aagggaatga ccatccttct ttacagaaga taatttttgt tgttccatat
    18001 taagtgtgat ttgtttttct ttaatcattt cttgttggtt attcagagaa tattgaagga
    18061 caaaaattat aggtaatata aaagccaaag tagttataat acggcgtctt gtttttttaa
    18121 tactaccttg ttgggtagta ggattcactt gctgtgaggg tatattagga tttgattggt
    18181 gtgatgatac ttttgggatg tttcccatta aaatgcctcc attactgatt gtcgaattta
    18241 aaccttttaa aactattata aatgttcaat agggatttta gaagatattt taatatagga
    18301 gagtttgtaa aatttaaaaa aatctttatt taaataaaag aaaccccgat tgtctgtggg
    18361 gctcctgaag ataatgaaag tactcgaata attaaagatt ccatgaattt tttggtgaaa
    18421 atgccggtaa attcgtctga attaatgaga gcatctaaag ctttatacgt acgtgaagta
    18481 attaaaaatc gatttataag agttagcttg ttttttctta ataccccact taatcagtaa
    18541 atatatatgt ctgttgaaat ctttacgtgt tcattgacaa aaagctgact atattcagtc
    18601 agctttttgt ataatacatt ctagtattta tcggttccaa aaaacatatt ctttccttta
    18661 agttgacatc aaaaatatta ccaatttttt cttttacaat ggcaacaaat aaagaaacat
    18721 ttacaatgac acttatttcg tttagaactc caatcatcat cacgatgaca cttttcttta
    18781 gatttccacc aatcatcatt acaatgtttt tcctgagaac tccaatcatc atcacaatga
    18841 tgcttttctt tagatttcca ccaatcatca caacaatgct ttttctgaga actccagcaa
    18901 tcatttttcc aggacattta tttctacctc ctttcaatag tgttcatatt attctatgtt
    18961 ttaataaaaa aatggcttgt ttattaacct actattttat ctttatatga tagagtgtct
    19021 tctactcgat atagaattca tacaaactat gctaattttt aagagaaagt ggagagaact
    19081 actactagtt atggtatttt tcaataaaca cttgttgaag aaaatgttct gattacaaat
    19141 aatatcttat tttcgagtac gctttttaaa tgtatatttc acaatgaaaa atgggaaatc
    19201 cacaaataaa gtctatgtat atgtgagtta atggaaaaat ctagtgtgtt tttaaggggc
    19261 gtcttattta aaagaaaaaa ggtttgtttt agaaagtggt gtctaaacat taaatggagt
    19321 aggactaaat tcacggccgc tcattaaaaa gcttttaatt aggagaagtc tgtttttata
    19381 atgaataatg aaaagaaagt ttggtacaat tgtttgtttt tttcttttta tgtgtttgcc
    19441 tcgtaccctt ttaagctagt ggacatactt tactaataga aaggattagg gggtgaggta
    19501 ttgggttctc gatttaataa ttgtaaaaag aagtgtacat gtaaacaaga tgattgttgg
    19561 gaagtattcg aagagtgtaa aaaagaacag catgagaaat gtgataattc ttgtgtacaa
    19621 ggaattagag atgaacttaa gaaattaatt aatcgaacag ttcaaattaa tacagaggga
    19681 cgtacttatg taggtactgt ttcgtctgta agttgtgatg tagttaggct tgcggctatt
    19741 cctggatcgg ttggagtaat tatttccatt tgtaaaattg aagcaatttt cccacctgtt
    19801 acaacggtta ctgctgactt tgattttaat ggtattgatg tagcaaacaa agcataatta
    19861 tgctgctttt ttgtaaagcc attcacatga atggctttat tttaatttca tataaaagga
    19921 gaatatattc tttatataga aataagtttg aggttataaa gtatgatgta cgaaaggagc
    19981 atggaattga ttaaactaaa aacctttaaa aaatctgatt ttaaacaatt aataaattgg
    20041 attaattctg aataatttct aatacaatgg tcaggaaatg ccttcacatt tcccttagac
    20101 gaacagcaat tagagaagta tatagaaagt gcaaatacac tcgctttcaa agtggtagat
    20161 gaagagactt cagacgttat tggtcacatt tcgcttggcc aaatagataa tattaataat
    20221 tcggctagaa ttggaaaagt attagttggt aatacgaaga tgcgaggaca ttctatagga
    20281 aaacatatga tgaaagcatt acttcatatt gcttttaaag aattaaaact acatagagta
    20341 actcttggtg tgtatgattt taatacatcg gccatttcat gttacgaaaa aatagggttt
    20401 gtaaaagaag gcttattaag agagtcaaaa agattaggag aaacgtattg gaatttatgg
    20461 gaaatgagta tgttagaata tgaatggaag aagtagcaac gatagtattt tataattata
    20521 ttatgttaac aaaaggggct tggtgggtat agtggataat aaaacaaaaa taatttcaat
    20581 tgcagctgtt tcgggggaga gctagtatgt taaaactgac aaagaaacca tttttgaaaa
    20641 aggcccacct gcattgtttc tgaggaataa gagggtgagc cctaattaaa cgaaactgaa
    20701 tgaatctgta aaaattgtaa ctaaagtatg catcaataag gtattaaaag ggatgaatag
    20761 taacctttat agattattcc atatatagca aaactggtta gcttctgatt taagcgctac
    20821 taaatgatta ttattaatag agttattcgt atacattctg ttcttttgga tgttaagtac
    20881 cgtataattc acatcgtttc gttcatttga aaatgttgat tcatttaata gtgtaagtgt
    20941 cgagttaatg ttgtacttat caattcgctc tttttttcct ttgaaaaaca gtttgataag
    21001 atgtggctca ttattaatga ataagccaag ttcaggtgat gaacggacga ttaaatcatc
    21061 tgatttccaa tgtgatttac ctggatcaaa ccaagagatg tctttatttt taatgaattt
    21121 tttgtattgc tttatgacat caatgtagtt ttgttttttt ttctgatcaa ccgtttgtac
    21181 taatgtttcc aaatattcaa aaggtagttt gttttgatga aatttaataa cagtttctcg
    21241 taattgtttc cagtaatcaa aagctggttg atattcaggt tgggatttta gattttttat
    21301 aaaggttgtt ttagctgtac tacctttcag tgtgaagtct aaaaattgtg taagccctac
    21361 tttaatttct ttcatattat atccccttcc aaacattatt catttaataa tagacgaaaa
    21421 atccgacatt tttaaagaaa tgagctagat gctagaaaat ccaatatcca tgcacaatag
    21481 atacgggaaa gccaatccgt aagtataaat gatggaccat tcaattgaag ataaattagg
    21541 taataggatt ttaccaggtg ataggttatt aataaaatca gatagtgagc tgattttaaa
    21601 agataacaat atagattatt tagcttggat ttgagaaaaa aagtacatgg gaataaagag
    21661 ggatataggg aaatgggccc tcatcaaaaa atataagttg gtatcagtat accgtagaga
    21721 atgagtgtat agaacataca agtaaaagta ttggcaagca tacttaaaat aagccgtata
    21781 aaaagttaat cattgtgtgc tttgataata tagcgtcagc gaaataaata gtgtgaagga
    21841 gagctatctt aacaagtatt ttatgtaacg ttcgtatatt tgaattttct tgtaattaac
    21901 cgaattctaa ttttttagaa acggataatg aggtatgggt gttgatcttt tttattgaat
    21961 aaaatggatt gatttttcgg attttcatta caaaataaaa atttaaattt tgttagttgt
    22021 taaaaaaaag atgagaagaa aatagaaaaa gagggctaat gcccgctttt tcttttaatt
    22081 tggtaattaa tcacagattg gtatcccaag cactcttaga gctaatgcta cttgaaggga
    22141 aatctctaat ctagcaattt caataccagc tactgaaaga actaaaaaag gttgtccgtt
    22201 tacaaataca acacaactat ccatagttaa gcctcctttc tagtaatcta ctatagtata
    22261 tgagtagaac tttaaagtgt aatagttcaa ttgttggatt taatagaatt aatagattaa
    22321 cccatttaaa ctaaacaaac gaatacaacg aaaggaaaga gagatggatg tatgcctcaa
    22381 aaaacatagg ttttaagaca tgtaatcgta catgaaatcc atcatattgg tcagctatct
    22441 atatgggcga gggagttaaa cttgcaagca gtttcagcaa atttgattgg acgaggatga
    22501 tagaattaaa aaccgacttg catctcaagc gcaagtcggt ttttatatat aagaagattt
    22561 cttaattgaa atcctcggat tttttctgac gtatatgtaa aaacattaag gtggtaatga
    22621 ttaagaaaat cattatagtt tgtataatta agtttttaaa ctgaagcaat attgtccaag
    22681 atgtaagggt gtctttaaaa gcttggagtg cagagtacga ggaaggatca aaaccatact
    22741 gtagcaactt ttttgtttca ataaatgaga tgttttcttc atctgcatct aatattactg
    22801 aaattagtct agtatctcct agttttgctg tactgacaaa actataatta ccgttagttg
    22861 aaaaactagt ttgtaagcca tcaacacctt gaagtttaat gttttcatta agggaatata
    22921 tcattttatt cgtattgaaa acctgggaat ctttgaaggt aaattggtaa gaggttagtt
    22981 tcgtaatatt caatacatct ggaaaatctt ttactaatcg tgcagctagt ttagctgcgt
    23041 ctattgctgt tgtagttgat tgtttatttg tatcatgatt aattccagta gagtttagaa
    23101 atggagatgg ttgtaataac tgtagttctt ttgctttttt attcattaat attgtaaagt
    23161 tatcttcagt tccagcaatg tgttctgcta gagcgagtgc agaacgatta ttccctgcca
    23221 gtagcaatac atgaagtaaa tcacgaaccg ttgttttatc attcgatgtt acttgtatag
    23281 ggcttgtttc tactcggaaa acttcgttac ttatttgtac gaagtcatct aactgtattt
    23341 ttctatcatt tagttgttcc aatacgatat attccgtcat taatttagat aaagtagctg
    23401 attgtactgg ggtttcttca ttttttttat aaacaatttc acctgaatta gcatttatta
    23461 agatagctga tttagcttga ataatcggac catttacata aagataaaaa tataaaacga
    23521 taagtgcagt aatgaaaaaa gataataata aaatagcgaa tttttttaag aattgcataa
    23581 gtgatcctcc tattatgaca tcaataatag tattgtaaaa aggaatgctt aattaggaag
    23641 aaagaaaagg taaagaattt ctaaagaatt ataaaggatt attaaattta gggaaataat
    23701 agaaaaagtt caatttctta tatgataaga aattgaactt tttatttgta atattaacat
    23761 ttgtatggaa gtagttttac agtgaatgtt gttttttcgt catcactata tacttcaatt
    23821 gttcctttat gcaactcgac tatacttttt gcaattgcta atccaagtcc agatccacca
    23881 gtatttgtag agcgagattt ctcaacgcgg taaaaacgtt caaaaatatg aggtaaatcc
    23941 gtactaggaa taggttgtcc gtaatttgtt atatcaattg taatcatatt attgctttca
    24001 taagcagtaa ggtcaatata gcgaccttcg cttccataag cgatagcgtt tataataaga
    24061 ttttcaaaca cacgcactaa tttgtcacca tcagctaata ccatgagctt ttgagacggg
    24121 aaagaaggcc gacattctat attagcttct tgaacctgta tgcggaattg aacagttaat
    24181 tgtccaagta attctacaat atcaatagga acagaataca agcttaattc tttattttga
    24241 acacgtgtat attcgaacaa gtcattcatt aatgcattaa gacgagttac tttatcgtaa
    24301 atgacttgaa tatagtatcg caattccact tcatctctat aattatcatg atggattaaa
    24361 tttacgtatc caactataga agtaagggga gtgcgtaagt catgtgatac atttgtaata
    24421 agttcacttt ttgcttgttc agcttgtctt tcttcatcaa tggagacttt taattgttca
    24481 acaatttcat tgaccccgat tgctaattct tctagataat tatgatttac aatagaaact
    24541 ttatgattga agtttccatt tgcaatataa cgaatttctt ctatcatttt ttttatacaa
    24601 gtttcataat aaagtttttt ctcgtgacga taaaaaatgt aaagatagga tgaaaaaata
    24661 gaaaataaaa acaaataaga tacaatcatc atccataaag actctttaat ccctttatac
    24721 ttttcataac caaaaattcg aatgaattct ttaccgagtt cagttagagt aagtgaactc
    24781 tcaattacac tcgtaacgag gcgataaata attagttcag taataggagt gagtgtgata
    24841 gctaataaaa gccaaaaaat aagtttccat ttaggaatat cttttaatat atcaaatgct
    24901 tcatttctca attttatagc caactcccca aacagtatga atcaattttt ctccattcat
    24961 tactgtttca agtttatctc gtaagttgct aatatggacc attaccgtct tatttgaacc
    25021 ataaccatct tcattccaaa cgcgttcgaa aatttcttct gaactaaata ctcttcctgt
    25081 attactcgca agtaaatata aaatatcgaa ttcaatagag gttagtttaa tatactctcc
    25141 atttacttta actgtatgat tatgtttgtg tatttcaaca gagcgaatac gaataatacc
    25201 atcttcattc ttttgcgaag tagcattttg gaaagagga
//
