LOCUS       NZ_CP018145            22622 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Brevibacillus formosus strain NF2 chromosome, complete genome.
ACCESSION   NZ_CP018145
VERSION     NZ_CP018145.1
KEYWORDS    RefSeq.
SOURCE      Brevibacillus formosus
  ORGANISM  Brevibacillus formosus
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Brevibacillus.
REFERENCE   1  (bases 1 to 6437015)
  AUTHORS   Fu,B. and Li,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2016) Insitute of Enzyme Engineering, Shaanxi
            Academy of Sciences, No 16, East Renmin Road, Xi'an, Shaanxi 710600,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3
            Genome Coverage                   :: 167.68
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 02:46:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,168
            CDSs (total)                      :: 5,986
            Genes (coding)                    :: 5,821
            CDSs (with protein)               :: 5,821
            Genes (RNA)                       :: 182
            rRNAs                             :: 16, 17, 17 (5S, 16S, 23S)
            complete rRNAs                    :: 16, 17, 17 (5S, 16S, 23S)
            tRNAs                             :: 127
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 165
            CDSs (without protein)            :: 165
            Pseudo Genes (ambiguous residues) :: 0 of 165
            Pseudo Genes (frameshifted)       :: 85 of 165
            Pseudo Genes (incomplete)         :: 95 of 165
            Pseudo Genes (internal stop)      :: 22 of 165
            Pseudo Genes (multiple problems)  :: 35 of 165
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:35:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2392507
            Orig. end                         :: 2415129
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP018145.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22622
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="9"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22622
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22622
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12622](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12622)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(289..1320)
                     /locus_tag="BP422_RS10910"
                     /old_locus_tag="BP422_10605"
     CDS             complement(289..1320)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007729333.1"
                     /locus_tag="BP422_RS10910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10605"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_088907746.1"
                     /transl_table=11
                     /translation="MKPFNKWTKAFMALTLATGLAACGNQASTDAGQTQAPADKATEPT
                     ELTIALDWYPNAVHSFLYVAEEQGYFKDENLKVTMQMPSDSNDPLKMAAAGKVDLAISY
                     QPQLIQARAEGVPVVSVGALVRHPLNVIMTRQDSGIDTPQKLAGKNIGYPSLPLDESIV
                     RQVVKHNGGDDSGLTFTDIGFDIVPALTAKKVDAVVGGYINHEQLILEKHGIPVNVFKP
                     FEFGVPDYYELVLATSDETLGKKQKAVEGFLRAIGKGQDYVKNNKEKALDLLLAKQAAD
                     FPLEKDIETKSLDTLIPLMDAGEKPFGYQTVESWQTLIDWMKKEKLITTDVKAEEIMRD
                     LVK"
     gene            complement(1317..2075)
                     /locus_tag="BP422_RS10915"
                     /old_locus_tag="BP422_10610"
     CDS             complement(1317..2075)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017248963.1"
                     /locus_tag="BP422_RS10915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10610"
                     /product="ABC transporter permease"
                     /protein_id="WP_088907747.1"
                     /transl_table=11
                     /translation="MGRGIWFGISIAIFLLVWEAGCRLLGVPPFILPPPSAVVVSLWDL
                     RASLVGVHLWATLKEVLLGLSISIVFGISLAFAMIRSRIVERLVYPYIVISQTIPIIAL
                     SPVFILWFGYDLSGKIAVTILFTFFPIVVNAYDGLRSTDKEMLQLLKTMGATNGQIFTK
                     LQLPSSLPHFFSGLKVAATYSVAGATIGEWLGASEGLGYFGRRASGNFQAPALFASVLL
                     LSILGMLLFWLAGRIERHFSPHMKIKGEQQ"
     gene            complement(2075..2857)
                     /locus_tag="BP422_RS10920"
                     /old_locus_tag="BP422_10615"
     CDS             complement(2075..2857)
                     /EC_number="7.6.2.14"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007729340.1"
                     /locus_tag="BP422_RS10920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10615"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_088907748.1"
                     /transl_table=11
                     /translation="MGEQLAFADVSFSYGDRQILDHFDLRVEKGEFVSLIGPSGIGKST
                     LFQLIAGLLEPGQGEIRLGSVPVANRLGKVGYMPQRDLLMPWRTIVENAALPLEIKGMT
                     KKEAHERVRQQLPRYGLQDWADRYPAQLSGGMRQRVSFLRALFSGAEIMLLDEPFSALD
                     GITRMDMQEWLMEKWQETGSTMLMITHDIDEAILLADRIIVLSGSPITKPIELTVPVSR
                     PRTASSRNQAGFLALREQIWELLRQERQAAMKPLRREA"
     gene            complement(2842..3522)
                     /gene="tenA"
                     /locus_tag="BP422_RS10925"
                     /old_locus_tag="BP422_10620"
     CDS             complement(2842..3522)
                     /EC_number="3.5.99.2"
                     /GO_function="GO:0050334 - thiaminase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tenA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007729343.1"
                     /locus_tag="BP422_RS10925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10620"
                     /product="thiaminase II"
                     /protein_id="WP_088907749.1"
                     /transl_table=11
                     /translation="MATFTDRLRKSVAPIWERVHQHPFVTGLGDGSLPVGAFKYYMKQD
                     YIYLIDYAKMFAIASVKAYDLETSSRFAALQESTLNTEMELHRQYAERFGISRAELEAT
                     EPSFVMLGYTSYMLRVAHQGSLAELVSALLPCTWSYWEIGKRLAQVEGALDHELYGEWV
                     RMYSSDEFGQLAIWLIDIMNQLAEGKSEQELAKLEEYFVNTSKMEYMFWDMSYREEMWP
                     WENN"
     gene            complement(3530..4825)
                     /locus_tag="BP422_RS10930"
                     /old_locus_tag="BP422_10625"
     CDS             complement(3530..4825)
                     /EC_number="3.5.1.16"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017248966.1"
                     /locus_tag="BP422_RS10930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10625"
                     /product="acetylornithine deacetylase"
                     /protein_id="WP_088907750.1"
                     /transl_table=11
                     /translation="MSSVDRLTEAVESIASRKEELFALLAELVSHPTVSPPARNSDAAQ
                     GVIANRLQAMGFEVDRWTVYPGDDNIVGRLSGRASTHANSLIINGHIDVAEVGDDTGWT
                     YPPFALTHGKDGRLYGRGVADMKGGLAASLFAIQILREHGVELQGDLLFQSVIGEEAGE
                     AGTLVAIERGYQADYAVVVDTSNLQMQGQGGVITGWITIESPTTLHDGMRAQTIHAGGR
                     VRGASAIEKMTKVITALQELERDWAVMKSYPGFPPGSNTINPAVIEGGRHAAFIADRCA
                     LWITVHFYPNESYEEIIREIEDHVGRAAAADLWLRDNPPTFRWGGRSMIEERGEIFLSL
                     ELDTEHPGLAMLQSAYESHMHQTPIVNMSPTVTDAGWFAHAGIPAVLFGPGELTHAHAV
                     DESIDPDQLVHFAQIMARFIATWCNTPKEAKE"
     gene            complement(4818..5591)
                     /locus_tag="BP422_RS10935"
                     /old_locus_tag="BP422_10630"
     CDS             complement(4818..5591)
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007729347.1"
                     /locus_tag="BP422_RS10935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10630"
                     /product="thiazole synthase"
                     /protein_id="WP_167385117.1"
                     /transl_table=11
                     /translation="MMDTLKIGPYEFRSRLLLGTGKFADLDTQGKAVEVSEAEILTFAI
                     RRLNLENPQEPNFLEQLDLKKFTLLPNTAGAYTVEEAVRIARLAKASGLCDMIKVEVIG
                     DPKTLLPDPIGTLEASKILVEEGFIVLTYTNDDPILARRLQEVGVHAVMPGASPIGSGQ
                     GIVNENNLRFIIEDAKVPIIVDAGIGSPADCAKAMELGADGVLLNTAVALADNPVLMAE
                     AMKLGVEAGRKGFLAGRIAKKRYASASSPTEGMIE"
     gene            complement(5597..5800)
                     /gene="thiS"
                     /locus_tag="BP422_RS10940"
                     /old_locus_tag="BP422_10635"
     CDS             complement(5597..5800)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016743632.1"
                     /locus_tag="BP422_RS10940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10635"
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_016743632.1"
                     /transl_table=11
                     /translation="MIVQLNGKKVELAEEITTVRALLASYSLQEKIVVVERNGDIIDRS
                     AYEQTPIADGDRIEIVHFVGGG"
     regulatory      complement(6000..6110)
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(6056..6073)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.23"
                     /tool="antismash"
     gene            complement(6152..6535)
                     /locus_tag="BP422_RS10945"
                     /old_locus_tag="BP422_10640"
     CDS             complement(6152..6535)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007729350.1"
                     /locus_tag="BP422_RS10945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10640"
                     /product="kinase-associated lipoprotein B"
                     /protein_id="WP_088907751.1"
                     /transl_table=11
                     /translation="MNWNPGDIVRVTQRTGEYIAEVLEIHDSKLLVKVLAVTKYPTQGD
                     LHSSYEVDVPLFHQRPALSYMEKFMTPAQGVIRYNGAIPDYKESVRQAMEREMEKLAKM
                     AAWAERCLVELEKMHKEAFTNTK"
     gene            complement(6569..7780)
                     /locus_tag="BP422_RS10950"
                     /old_locus_tag="BP422_10645"
     CDS             complement(6569..7780)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007729351.1"
                     /locus_tag="BP422_RS10950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10645"
                     /product="DHHA1 domain-containing protein"
                     /protein_id="WP_088907752.1"
                     /transl_table=11
                     /translation="MDDRLYYQDAYTRTFSAQVTRTGVEQDGTPYVVLNQTAFYPTGGG
                     QPSDLGVLEEIRVVDVEEVDGEIRHRLEAPLSESIGEVTGHIDWDRRFDHMQQHAGTHI
                     LSASFLEVVQAETVAFHLGKERVTIDVRLDELTADVWEKVEKRANQIVMENHPIIARFV
                     DDEELATLPLKKQPTVTENIRVVMIPDFDYNPCGGTHPARTGEVGMIKILGWEGHRGNI
                     RLEFICGWRALRDYNQKQAVVRDTAKLLATNEGELIAQTERLLAERDTLKAKLAEVDKQ
                     LLGVEVNQQLAAASQLGHSHLIMCTFTDKTIQQLQQFAQLATALAPDAICLLAATTEDK
                     VQVVFARGQEVNVAINQVLKETLPVINGKGGGNPAMAQGGGQSVVDAEDVLLHARKLLE
                     ASLM"
     gene            complement(7862..8089)
                     /locus_tag="BP422_RS10955"
                     /old_locus_tag="BP422_10650"
     CDS             complement(7862..8089)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005828760.1"
                     /locus_tag="BP422_RS10955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10650"
                     /product="hypothetical protein"
                     /protein_id="WP_236841360.1"
                     /transl_table=11
                     /translation="MGECKLDHSHEDVLKKLAEQAPHLSELRVSQFKHQLNGELSQERL
                     NELFHLLKKYDLASPEERQEREKQMDHLFG"
     gene            complement(8185..9468)
                     /locus_tag="BP422_RS10960"
                     /old_locus_tag="BP422_10655"
     CDS             complement(8185..9468)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017248973.1"
                     /locus_tag="BP422_RS10960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10655"
                     /product="glycoside hydrolase family 18 protein"
                     /protein_id="WP_088907754.1"
                     /transl_table=11
                     /translation="MQIHVVEEGQTLASIAETYGTTPEAITEANELPDPNKLVTGQAMV
                     IPIVGSYYWVKQRDTLYTIGQRYQISAAELARINRIPQYRPLQVGQRLYIPPRPRRAAD
                     FNAYVEPRRTVTPAMEADVRTAAPHLTYLAPFSFRIRRDGTLVRPTLNNFPQIAKENQV
                     LLMMVITNLEREQFSTELGELILNNQELQNTLLNNILQTARELGMGDIHFDLEALPTTG
                     AEAYANFLRKARDRIHAAGLMMSVALAPKTSAEQAGKWYTAHDYKAIGAIADFVVIMTY
                     EWGYSGGPPMAVSPIGPVRRVLQYAITEMPADKILMGQNLYGYDWTLPYERGTTARALS
                     PQAAIALASQHNAVIRYDYRAQAPFFTYTDNQGKQHRVWFEDARSIQAKFNLVKQLGLR
                     GVSYWKLGLPFPQNWLLIEENFRVRKRS"
     gene            complement(9533..9841)
                     /locus_tag="BP422_RS10965"
                     /old_locus_tag="BP422_10660"
     CDS             complement(9533..9841)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017248974.1"
                     /locus_tag="BP422_RS10965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10660"
                     /product="thioredoxin family protein"
                     /protein_id="WP_088907755.1"
                     /transl_table=11
                     /translation="MQELTSTELIQYLQERESVALFVYTPMCGTCKLAARMLGIMQETL
                     PTVPLYQININTAPALAEQWQVTSVPALLIFHKNELIERHYAIQSVGFLYEVLKPLA"
     gene            complement(10001..12622)
                     /gene="lanKC"
                     /locus_tag="BP422_RS10970"
                     /old_locus_tag="BP422_10665"
     CDS             complement(10001..12622)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017248975.1"
                     /locus_tag="BP422_RS10970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10665"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_088907756.1"
                     /sec_met_domain="micKC (E-value: 1.8e-136, bitscore: 454.8,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 6.2e-16, bitscore: 57.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.4e-11, bitscore:
                     41.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKANMVYYDYLNENSKYFTPNKSIVTEREFNVTNLSDDCVVSREE
                     NSVWKMYKFKERSLQAQGWKIHISATLDNAEQILQKVSHILVERKVHFKHLASEWDYFT
                     TNSKTANRASSGKFITIYPPSDDDFLNLLDLLYTTLHSFESGPYILSDKCWKNSNVYYR
                     YGGFAMIFNEQGELCMKDENGELLVDERVPYYKVPTFVKEFDQYLDSLNTTSIEADVEN
                     NKFEEYEFQSALRFTNGGGIYVTERKKDKKKVIIKEARPKSGLDGQKVDALERQKIELD
                     ALSKLSKVDGIVNILDYFTHWKHSFLVEEYVDGIDLDSWIVANYPFINNGDIKVYKNKI
                     HNILTKLVSIVEEMHKNGVGMGDLQPANIIISEDLNVTLIDFETARPKDSEGKPTLQTY
                     GFSHPRNKNNGERDWYAIKKILRHCLLPIGPIEDIDSDMYDYQDQWIEKVYGEDFLLFV
                     KMIREKCNQHLSFIGEENRSHAINKNAMKKDVSSIIEGLRNGIEKNFVRSEKLIHGDIR
                     QYESKAGKYNVQNGGTGAALAFFRSGTVSENINHWIENELMRNIDSIEQGGLLTGKAGI
                     GTTLYEIGYKKEAMNIFANMNLNSSDISLRSGLSGIGLGFVSLYLEEKDERFLDKAIFV
                     ASIIDTFMSEKKELKVQDWAGIPIGIMDGWSGVSLFYSALYAVTKKENYYLKSIECIDK
                     DLEKTKEDKSTLQTIDDSNRLLPYLSGGSLGIGIAIVYLNHVSDKKRYQRELSLITNLY
                     RVRCSLSGGLYDGAGSFLIIPPLLGKSDSEYTNKKDCVIELLRLFLIPKENHILFPGQF
                     CYRLSDDFQTGSSGIILALEGILKDNPLYWLPLINIDDFYKNTKYSQDVACVNAAPTTI
                     KQ"
     CDS             complement(12764..12868)
                     /gene="allorf_2405271_2405375"
                     /locus_tag="allorf_2405271_2405375"
                     /protein_id="allorf_2405271_2405375"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MNQVLNLQKLPQNEASEVAARWSLYSNICPWPWG"
     CDS_motif       complement(12809..12868)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNQVLNLQKLPQNEASEVAA"
                     /locus_tag="allorf_2405271_2405375_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(12764..12808)
                     /prepeptide="core"
                     /locus_tag="allorf_2405271_2405375_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="1.20"
                     /molecular_weight="1729.0"
                     /monoisotopic_mass="1727.8"
                     /core_sequence="RWSLYSNICPWPWG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNQVLNLQKLPQNEASEVAA"
                     /leader_location="[12808:12868](-)"
                     /alternative_weights="1747.0"
     gene            complement(13217..14107)
                     /locus_tag="BP422_RS10975"
                     /old_locus_tag="BP422_10670"
     CDS             complement(13217..14107)
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007729360.1"
                     /locus_tag="BP422_RS10975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10670"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_088907757.1"
                     /transl_table=11
                     /translation="MEAIGVIGIGAMGKGMVCNLLQKGYHVYAYDPSPAAKAWAKERGA
                     IVVESPQAVGSVARVVFTSLPGPAIVEEVMLGADGLFLSLGAGSFVFDTSTIDPATAKR
                     LNQHGVEKGIYYYDCPVSGGPAGSAAGTLTIMVGGDEAKLPEIMDYLRAIGKEIFYLGE
                     SGSAQVAKLCHNSVVAVITAALGEAFTVGAKAGVDPHKLAAVMDKGSAHNRVLSVFGPN
                     ILYGTYENTVFSLDHMHKDLQLYAQTAREQQVPVLVGGTVAQMYEAAKAQGKGSWDSSA
                     VCTVTEELAHTTISR"
     gene            complement(14134..15585)
                     /locus_tag="BP422_RS10980"
                     /old_locus_tag="BP422_10675"
     CDS             complement(14134..15585)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007729364.1"
                     /locus_tag="BP422_RS10980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10675"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_236841361.1"
                     /sec_met_domain="Aldedh (E-value: 2.9e-159, bitscore:
                     528.9, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVTYNNYIAGAWVASHTGQVFPSTNPANTNEVLGYFQKSDGLDA
                     RSAIEAAANAFGEWSQKSAPTRGEFLFSLIHLLEKHKEELAETITREVGKTLREARGEV
                     AKTITSMKQLTGEATRLTGQTVPSFDERVIGYTVREPIGVFAIIAPWNFPLGIGLWKIV
                     PAILAGNTVVFKPASNTSLISVKLVELLIESGVPSGVVNLVTGPGAVIGEELTNHPLVK
                     GISFTGSSEVGLALGRAVGARGGKIQAEMGGKNPAIILADADIDLAIDSIVLSGFFDNG
                     QRCTGTSRVLVVPEVAEQVKAKLIERAKGLKIGNGFDPDNHNGPVVDEHQLNLYLHYVQ
                     KGMEEGGVLECGGKRLVEDDLAQGYFVAPTVFTGITQEMTIANEEIFGPVIAVIDVDSF
                     EHAMQVANQVEFGLSSTIFTNDLQKAFQFVKGIQSGVTHVNMPSTHFESQFPFGGKKIS
                     GLGPREQGESAFDFYVETKTVYIRP"
     gene            15709..17844
                     /locus_tag="BP422_RS10985"
                     /old_locus_tag="BP422_10680"
     CDS             15709..17844
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007729366.1"
                     /locus_tag="BP422_RS10985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10680"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_088907758.1"
                     /transl_table=11
                     /translation="MNSFSLLLEKLHKWFGDQPFSILFQFSRDRHFRLVFSSFHENAAT
                     NIPPMTVPLCDNDASHMRYAFESLPSQQMYRFFYENEGQAVICLAHQAKLPIILTADQW
                     ELLWFGFRLLLAEEKMTAKTEESKKLFEGIRSISATLDVHQIIRGIIGNALAVIPAADA
                     GLLHLYDPTIDRLIPKATVGFHDTVFKDLKMRVGESIAGKVFEDGIPRMYKTSQETTHA
                     MKDISADNFHSLNHAKALRDLNGLLCVPISREEKRIGVLVLHQFHQENVFTDYDLDLLQ
                     GFADQTSIALQNAELYAEVKQAYEHMASISAQLQAKHDDLIQRNHIHESIKQLSLQNKG
                     AETIVKTLSKMTGHSIYFADWLEQKMYPEKSAVFFSWDELYTLLNKKRQPVSVNLFTPA
                     SGDDQLFCLYPLINGSIFLGCLMIPLDERGLSDLARMTVEQGSAVLILDLVKKQSISSV
                     LYKRAHDLFQELIASKGNELFDRARSMGLQPQAEYYVIYAHLTQCHDLALLEANIHRLI
                     TRWKWEFSKTQMLVYGFHNHVTLLIRSLGSRDGKDIRERLQQASDEWELGKEASLSIGV
                     GSMASGIEQISKSYEEAKKAAHYLTNRGRSGVVYYKDLGVNRLMLNQSQADIDAFIQDV
                     FAPFWQDPEKYQEWEQTIITYMKCSQSPQLTAKELHIHVNTLYQRLRKVEELLHIDLRN
                     PEDLLKLQLACHLRQEG"
     gene            18147..18743
                     /locus_tag="BP422_RS32070"
     CDS             18147..18743
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024157.4"
                     /locus_tag="BP422_RS32070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_236841362.1"
                     /transl_table=11
                     /translation="MFAQKMVQGTELTTDCFHSATNLFEALKHHVSIKGVIAGVIPGRV
                     FLSNDARSALLTSPQGIFLGGSVDNPLFFKEVNTLLKEELLPQLAADEQLDYVLFYPTD
                     EKWDDILDIVMKDVFPMRSGRMIFTHHLEDLSPLADDHIFPINSTLLKRKELVGLEDVI
                     DEIAENWPSIEAYENKGFGCAAIQDTDEGPPNNAG"
     gene            18749..19177
                     /locus_tag="BP422_RS32075"
     CDS             18749..19177
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BP422_RS32075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_236841363.1"
                     /transl_table=11
                     /translation="MGWQCWSNNIGSQRTALSVGFELLADFPVLFGWNLPLNNFLVNGN
                     HYMRGDLKYGVEKDYARAAWSYAQALDEGWDWNGDAALYWNAACLFYLSGEEDRAKHYY
                     KKAIEHGWVSIHHPHYHDDVYREQDSEQIARILAESLK"
     gene            complement(19448..19888)
                     /locus_tag="BP422_RS11000"
                     /old_locus_tag="BP422_10695"
     CDS             complement(19448..19888)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BP422_RS11000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BP422_10695"
                     /product="hypothetical protein"
                     /protein_id="WP_236841364.1"
                     /transl_table=11
                     /translation="MTKLFQLNSEDDIEKVVAQSQQIAQKALQEYDLDGEHADEKITED
                     QVYKEGVLLAKLHTVSQDFQLPPEFARPIWGEDSFKQSMSRLREHYQQFLTDEEFVLYQ
                     LAADKILTCLAKLDMNSSNYGVIHGNLHQAIPFWGYILNKER"
     misc_feature    20024..20042
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.01"
                     /tool="antismash"
     gene            20024..20761
                     /locus_tag="BP422_RS11005"
                     /old_locus_tag="BP422_10700"
     CDS             20024..20761
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007729375.1"
                     /locus_tag="BP422_RS11005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10700"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_088907760.1"
                     /transl_table=11
                     /translation="MLYTVNDVAKLSGTTIKTLYHYQKIGLLMPEIVTENGYRYYGENE
                     LKRLQQILFYRELDLSLDSIKAALDHEPDRLRCLCEQQTMLKARQLRLERILNTLEETI
                     QHERKRGNMSTENMFDGLNEEEWKQAFTQQNEHLQKAYDFQFDTENLDVTSLNEKAAEA
                     KAFMTFMADALKNNRSVDDKTVVSAIESHLAFLQKDHPIDAKAFAEQSRFFLSDEFHRT
                     MLEEQQTGLSYYICIAAENYASK"
     gene            complement(20844..21863)
                     /locus_tag="BP422_RS11010"
                     /old_locus_tag="BP422_10705"
     CDS             complement(20844..21863)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007729378.1"
                     /locus_tag="BP422_RS11010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_10705"
                     /product="serine hydrolase"
                     /protein_id="WP_088907761.1"
                     /transl_table=11
                     /translation="MQRSYWPTTEWQAADPAILNIDAEKLAELDPIIKSAYSNINGIVV
                     VRNGYLAHEKYYHGYGPKDRNHVASVTKSILSALIGIALEERFIKNVDQKVLEFFPDYA
                     PDHTDEQKQAITIRHLLTMTAPYPFEDWHEPLDKMCMQSDWVKYTLDMLGQKGTIGAFK
                     YSTAGAHLLSAILTRSTGKSAREFANERLFTPIGMEEIPDYEMKWFASDDLFGKDVRGW
                     VKDPDNNSTGGWGLTLTPRDMARFGWLYLNRGCWDNHQIIPEAWIDESIAMNPNQYGYL
                     WWLREEDGVFAYAAIGDGGNVICCIPEKNLVVAIASEFMPNPRDRWMLIKEHIIGAVI"
ORIGIN
        1 aaaggcattg agaaaggcat gctgcctgac ttggtggaat tgccttattc gtcaaaaaga
       61 aaatctccct cacacaatgg tcatggtctc ggtttgccca tggttgcacg tattgctgcc
      121 gctcatcatg gacacctgct gttaacaagc gatacaggaa aagggattac agcagaactt
      181 tgtttccccc tctcctccta aaagaaagag cacctcctct gtatcgccaa tggagagtag
      241 actctcaaaa gcgtgcaaag gggtgctttt tgactgattc tgggtcaatt acttcacgag
      301 atcgcgcatg atctcttctg ccttgacgtc agttgttatc agcttctctt ttttcatcca
      361 atcaatcagt gtttgccaag attccaccgt ctggtatcca aatggctttt ctcctgcatc
      421 catcaacgga atcagggtat ccaaactctt ggtctcaatg tctttttcca gagggaaatc
      481 cgcagcctgt ttggcaagca acagatcgag tgccttttcc ttattatttt tcacatagtc
      541 ctggcccttg ccgatcgcac gcaggaaacc ttccacagct ttctgctttt tgcccaaagt
      601 ctcgtcactt gtcgccaata cgagctcata atagtctgga acaccaaact caaaaggctt
      661 gaacacattg actggaatgc cgtgcttctc caaaatcagt tgttcatggt tgatatagcc
      721 acctaccact gcatcgacct ttttggccgt caatgctggg acgatgtcaa agccgatatc
      781 cgtgaaggtc agtccggaat catcgccacc attatgcttc acgacttgac gtacgatcga
      841 ttcgtcaaga ggaagtgatg gataaccgat attttttcca gccaactttt gcggagtatc
      901 gataccactg tcttggcggg tcatgatcac gtttaacggg tgacgaacga gtgcacctac
      961 agatacgaca ggaactcctt ctgcacgagc ttggatgagc tgtggttgat agctgattgc
     1021 caaatccact ttgcccgcag ccgccatctt caacggatca ttgctgtctg aaggcatttg
     1081 catggtcacc ttgaggttct cgtctttgaa atagccttgc tcctctgcga catacaagaa
     1141 ggaatgtaca gcattcggat accaatcgag cgcaatcgtc agctcagtag gctccgttgc
     1201 tttatcagca ggggcttgcg tctgaccagc atctgtgctc gcctgattgc cgcaagcagc
     1261 aagacctgtt gccaaagtaa gtgccatgaa tgctttcgtc catttgttga aaggtttcat
     1321 tgttgttctc ctttgatttt catatgcggg gaaaaatgac gttcgattcg tccagccagc
     1381 caaaacagca gcatgccgag aatcgagagc aacaggaccg aggcaaacag cgcgggagcc
     1441 tgaaaattgc cagatgcccg tctgccaaag tacccgagtc cctcgctcgc tcccagccat
     1501 tccccaatgg ttgcccctgc cacactgtag gtagctgcca ctttgagacc actgaagaaa
     1561 tggggtaaac tcgacgggag ttgcagcttg gtgaaaattt gtccgtttgt tgcccccatt
     1621 gtttttaaca gctgaagcat ttctttgtca gtcgagcgaa gtccatcata cgcgttgacg
     1681 acgatcggaa agaaagtaaa cagaatcgta acagcgattt ttccagataa atcatacccg
     1741 aaccacaaaa tgaatacggg tgataacgcg ataatcggaa tcgtttggga gatgacgata
     1801 tacggataga ccaagcgctc cacaatccga ctgcgaatca ttgcaaatgc aagggagatt
     1861 ccaaatacaa tcgagatcga tagccccagt aacacttcct ttaacgtcgc ccaaagatgt
     1921 acacctacta gagaggcacg taaatcccac aaagacacaa ccacagcgct aggtggtggt
     1981 aaaatgaatg gcggcactcc gaggaggcgg catccagctt cccacaccag tagaaaaata
     2041 gcgatggaga taccaaacca aatgcctctc cccatcatgc ttctctcctc aacggcttca
     2101 ttgctgcttg gcgctcctgt cgaagcagtt cccaaatttg ttcacgcaat gccaagaatc
     2161 cggcttggtt gcggctgctc gccgttcgcg gtctgctcac cggaacggtt aattcgatcg
     2221 gcttggtgat cggactacct gaaagcacga taatccgatc tgcaagtaaa atggcttcgt
     2281 cgatgtcatg tgtaatcatc agcatcgtac tgcctgtttc ctgccacttt tccatcagcc
     2341 actcttgcat gtccattctt gttattccat ctaacgcact aaacggctca tccaacaaca
     2401 ttatctctgc accagaaaac aatgcgcgta aaaaggaaac ccgctgacgc atcccaccgg
     2461 aaagctgggc tggatatctg tcagcccaat cttgaagccc gtaccttggc aattgctgtc
     2521 tgacacgctc atgcgcttct tttttcgtca tacctttgat ttccagcggc aaagctgcat
     2581 tttcgacaat cgtacgccat ggcatgagca gatcgcgttg gggcatataa ccgaccttcc
     2641 ccaaacgatt tgccactggt acactgccga gcctgatttc gccttgtccc ggctcaagaa
     2701 gacctgcgat gagttgaaac aaggtgcttt tcccgatccc gctcggaccg attaagctga
     2761 cgaattcccc tttttccaca cgcagatcaa aatgatcgag aatctgcctg tcgccatacg
     2821 aaaagctgac gtcggcgaaa gctagttgtt ctcccacggc cacatttcct ctctgtagga
     2881 catgtcccag aacatgtact ccattttgga ggtgttgaca aaatactctt ccagtttggc
     2941 cagctcttgc tcgctcttac cttccgccaa ttggttcatg atatcaatca gccagatggc
     3001 caactgccca aactcatcgg agctgtacat gcgcacccat tcaccataca gttcgtgatc
     3061 caacgctcct tctacttgtg ccaagcgctt gccgatttcc caatagctcc atgtgcatgg
     3121 gagtagtgca ctcaccaatt ctgccaacga cccttgatga gcaacacgca gcatgtagct
     3181 ggtgtatccc aacatcacaa acgaaggctc ggttgcttcc agctccgcgc gagagatgcc
     3241 aaaacgctcg gcatactgac gatgcagctc catctctgtg ttcagcgtcg attcttgcaa
     3301 agcagcgaat ctggagcttg tttccagatc gtacgccttc acactcgcaa tcgcgaacat
     3361 tttcgcgtaa tcaatcagat agatgtagtc ttgtttcatg taatatttga atgcaccaac
     3421 gggcagactg ccatctccaa gtccggtgac gaaaggatgt tgatgaacac gctcccagat
     3481 cggggctacg ctttttctca aacgatcagt aaaggttgcc atgctattct cactccttcg
     3541 cttcctttgg ggtattgcac caggtggcga tgaaacgggc catgatctgg gcaaaatgaa
     3601 caagctggtc aggatcaatt gattcatcta cggcatgagc atgcgttaac tcaccgggcc
     3661 cgaataggac agccggaatg cctgcatgcg caaaccagcc tgcatccgtc accgtaggcg
     3721 acatattaac gataggggtt tgatgcatgt gactctcata tgcggattgc agcattgcca
     3781 accccggatg ctccgtatcc aattccagtg aaaggaagat ttcaccgcgc tcctcaatca
     3841 tcgaacgccc accccagcgg aatgttggag gattgtctct caaccaaaga tcagctgctg
     3901 ccgcacgccc gacgtgatcc tcgatctctc gaataatctc ttcgtaggat tcgttcggat
     3961 aaaaatgaac agtaatccag agagcacaac ggtctgcgat gaacgcagcg tgacgacctc
     4021 cctcgatgac tgcgggattg atcgtattgc tgcctggcgg gaagccggga taggacttca
     4081 tgacagccca gtcccgctcc agctcctgta gtgcggtgat caccttcgtc attttttcaa
     4141 tggcagaagc tccccggacg cgtccgcctg catgaatcgt ctgtgcacgc attccgtcat
     4201 gcagcgtcgt cggactctca atcgtgatcc accctgtaat aaccccgccc tgcccttgca
     4261 tttggagatt gctcgtgtcc actacaacgg cgtagtcagc ctgatagcca cgctcgatgg
     4321 cgaccaatgt ccccgcttca cctgcttctt ctccgattac ggattgaaag agcagatcac
     4381 cttggagctc cactccgtgt tcccgcagta tttggatcgc aaacaagctc gctgcgagcc
     4441 cgcctttcat atccgcaact ccacggccgt acaggcgccc atccttgcca tgcgtcaaag
     4501 caaaaggtgg ataggtccac ccggtatcat ctccgacttc agccacatcg atatgtccgt
     4561 tgataatcaa gctgtttgcg tgggttgagg cacgccctga taaccgaccg acgatattgt
     4621 cgtctcctgg atataccgtc cagcgatcca cttcgaatcc catcgcttgc agtctgttgg
     4681 cgattacacc ttgtgcggca tcgctgtttc gcgcgggagg actcacagtc gggtgagaaa
     4741 cgagctctgc caatagggcg aacagctctt ctttgcggct ggcaatcgat tctaccgctt
     4801 ctgtcagtcg atccacgcta ctcaatcatc ccttcggtcg ggctgctcgc ggatgcgtaa
     4861 cgctttttcg cgatacggcc tgccaggaag cctttgcgac ctgcttccac tccgagcttc
     4921 attgcttctg ccatcaggac aggattgtca gcgagtgcga ccgctgtatt caacaagaca
     4981 ccgtcagcac ccagctccat cgctttcgcg cagtctgctg gagaaccaat tcctgcatct
     5041 acgataatcg gtactttggc atcctcgatg ataaagcgga ggttgttttc gttgacaatc
     5101 ccttgtccgg aaccaattgg tgacgcacct ggcataactg catgtacgcc aacctcttgc
     5161 agacgtctgg caagaatcgg gtcgtcattg gtgtaggtca gcacgataaa gccttcttcc
     5221 accaaaattt tcgaagcctc gagtgtgcca atcgggtcag ggagcagtgt tttcgggtct
     5281 ccaataacct cgaccttgat catgtcacac agtccagatg ctttagccaa acgggcgata
     5341 cgcactgctt cttctactgt ataggcacct gctgtatttg gtaacagggt gaattttttc
     5401 aaatcgagtt gttccaaaaa gttcggttct tgcggatttt ccaaattcaa gcgacgaatc
     5461 gcaaaggtca aaatttctgc ttccgacacc tctaccgctt tcccttgtgt atccaaatca
     5521 gcgaatttac ctgtccccag aagcaagcgg gagcgaaact cgtaaggtcc aattttcaat
     5581 gtatccatca tgatgatcat cctcctccga caaaatgaac gatttctatg cgatctccgt
     5641 ctgcaatcgg tgtttgttcg tacgcagagc gatcaataat gtcaccattt cgctctacga
     5701 cgacaatctt ctcttgcagg gaataagaag caagcaaggc acgcactgta gtgatctctt
     5761 ccgccaactc tacttttttc ccattcagct gaacaatcat tgattacctc cttctactgg
     5821 aaaaaaaacg gcttctcccg cctgcctgag tcggttcaga caaacagaag aagccgtata
     5881 cccatcccat ctcaccggac gaatggcata aaaaaaccat ccgccccgga tggttgagtg
     5941 tcatcttatc atctatgcgc ataaacaagc atagttccgc tcggatgcga cacgtgatac
     6001 tgattccaaa tacctcttcc tccgctggca tgacccaggt caggttcaac ggtcagtaac
     6061 acactcgtta caatctcagc caacgttgct tggcccccgt ttggtagtaa tgctatgcaa
     6121 ttgtcgtaca ttcgagtatt acagtaccac tctatttcgt gtttgtaaag gcttccttat
     6181 gcatcttttc cagctcaacg agacaacgct ctgcccaagc tgccattttc gcaagctttt
     6241 ccatttctct ctccatcgcc tgacgcacag attccttgta gtctggaatc gctccgttat
     6301 agcgaatgac cccttgtgca ggtgtcatga atttttccat gtacgacagt gctggacgct
     6361 ggtgaaacag cggtacatct acttcgtagg aagaatgcaa atcgccttgc gtcgggtatt
     6421 tggtaactgc cagcactttt actagcagct tcgaatcgtg gatttccaat acttctgcaa
     6481 tatattcacc agttcgctgc gtaacgcgaa cgatatctcc cggattccag ttcatcgcgg
     6541 tttcctcctt ttattcaatc gaatgcattt acatcagtga ggcttccagc agtttgcgtg
     6601 catgcagcaa tacatcttcc gcatccacta ctgactgacc gccaccctgc gccatcgcag
     6661 gatttccccc accttttccg ttaatgaccg gcaaggtttc tttcaacact tgattgatgg
     6721 ctacgttgac ttcttgtcca cgagcaaaca cgacttgcac tttgtcttca gttgtagcag
     6781 ccaagaggca aatcgcatct ggcgccagag cagtagcgag ctgtgcgaac tgctgaagct
     6841 gttgaatggt tttgtctgta aaggtacaca taatgaggtg agaatggccg agttggctag
     6901 cagcagctag ttgttgattg acttccactc ccaagagctg cttatccact tctgccaatt
     6961 ttgccttcaa ggtgtcgcgt tctgcaagga ggcgttccgt ctgcgcgatc agttcccctt
     7021 cattggtagc gagcagcttc gccgtatcac gaacgacagc ttgcttttgg ttgtagtccc
     7081 gcaaagctcg ccagccacag atgaattcaa gacgaatgtt tccacgatgt ccctcccagc
     7141 ccaagatctt gatcatccca acttcgcccg tacgcgctgg atgtgttcct ccacacgggt
     7201 tgtaatcaaa atcaggtatc atcacgacgc gaatattttc cgtaacggtc ggctgttttt
     7261 tcaagggcag cgttgccaat tcctcgtcat caacgaaccg cgcaatgatg gggtggttct
     7321 ccataacaat ctgattcgct cgcttttcta ccttctccca tacatctgct gtcaactcat
     7381 ccagtcgtac atcaatagtg acacgttctt tgcccaagtg aaaggcgacg gtctccgctt
     7441 gcacgacttc caggaaggac gcggataaaa tgtgtgtacc agcatgctgc tgcatgtgat
     7501 caaaacgacg gtcccaatcg atatgacccg ttacttcccc tatgctttcg gacaagggtg
     7561 cttccagtcg atggcgaatt tcaccatcta cctcttccac atctaccaca cgaatctctt
     7621 ccaatacgcc cagatcggaa ggctgtccgc ctccagtagg gtaaaaagcc gtttgattca
     7681 gtaccacata aggtgtccca tcttgctcga caccagtcct cgtcacctgg gccgagaatg
     7741 ttcttgtata ggcatcctga taatagagtc tgtcgtccat cgttactcct cgctgcatgg
     7801 aaccatggtt ccagcctgtg tctccctcta gggggcaaaa cgaaaaacat atgtataaag
     7861 cttagccaaa caagtgatcc atttgttttt cgcgctcttg gcgctcctct gggcttgcca
     7921 ggtcatactt tttcaataaa tgaaacagtt cgtttagacg ctcttggctg agttcgccat
     7981 tcaactgatg tttgaattga ctcacacgca actccgacag atgtggagct tgttctgcca
     8041 gttttttgag tacgtcctca tggctgtgat ccaatttgca ttctcccatg atttctcccc
     8101 ttttccttcc tgtcatcttc atcataccat gattttccat tcgaaaaaag gcgtacaatc
     8161 cgcgatggaa tgtacgccag ataactatga acgcttacgg acacgaaagt tctcctcgat
     8221 caacagccaa ttttgcggaa atggcaaacc caatttccag tagctgacgc ctctcaagcc
     8281 aagctgttta accagattga acttggcttg gatcgaccgc gcatcctcaa accacactcg
     8341 atgttgctta ccttgattat cggtgtacgt aaaaaacgga gcctgcgcgc gatagtcata
     8401 ccggatgacg gcattatgct gggaagccag tgcaatcgct gcctgtggac tcaatgcacg
     8461 cgctgtcgtc cctcgctcgt acggtaaggt ccagtcgtat ccgtacagat tttggcccat
     8521 caaaatttta tcggctggca tctcggtaat cgcatactgc aagacacgtc gtaccggacc
     8581 aatcggggaa actgccatag gaggaccgcc actatagccc cattcatatg tcatgatcac
     8641 gacaaaatcg gcaatggcac caatcgcctt gtaatcatgg gcggtatacc atttgcctgc
     8701 ctgctcggca cttgtcttcg gtgccagcgc aacagacatc atcagtcctg ctgcatggat
     8761 acggtctctc gcttttcgca agaagttggc atacgcttct gcaccggttg tgggtaatgc
     8821 ttccaagtca aaatgaatat ctcccattcc cagctctcgt gctgtctgaa gaatattgtt
     8881 caacaaggta ttctgaagct cttgattgtt gaggataagc tcgcccaatt cggtgctgaa
     8941 ctgctctctt tccagattcg taatgaccat catgagcaga acctggtttt cttttgcgat
     9001 ttgcggaaaa ttgttcaatg tcggtcgcac gagagtacca tcccgtctga tacgaaagct
     9061 gaacggagcc aaatatgtca gatgcggtgc agccgtgcga acatcggctt ccatagctgg
     9121 tgtgacggtg cgtctcggtt ccacataagc attgaaatcg gctgcacgcc gcggacgggg
     9181 cgggatgtaa aggcgttgcc cgacttgaag cggtctgtat tgcggaatcc tattgattcg
     9241 tgcaagctct gccgcactga tctgataacg ctgaccgatg gtatacaacg tatctctttg
     9301 cttgacccaa tagtagcttc ccacaatcgg aatcaccatc gcctgtccag ttaccaactt
     9361 attaggatca ggcagttcat ttgcctcagt tatcgcttcc ggggtcgttc cgtacgtctc
     9421 ggcgatgctc gctaaggttt gtccttcttc caccacgtgg atttgcatac tccccctcct
     9481 tcgcatttct tctctctttg tcatattcac ggcgaaggta ataggtgtat gtctaggcaa
     9541 gaggtttcag aacttcgtat aaaaacccaa cggactggat ggcataatgg cgttctatca
     9601 actcattttt gtgaaagatc agcaaggcgg gaacactggt cacttgccat tgttctgcca
     9661 atgcaggcgc cgtattaatg ttgatctgat acagcggaac ggtaggcaat gtttcttgca
     9721 tgatgccgag catacgtgct gccagcttgc acgtcccaca catcggtgta tagacaaaaa
     9781 gagcgaccga ctccctttct tgcaggtatt ggatcaattc tgttgaggtt agttcttgca
     9841 agtcgtatct ctcctttctg cacattggac acgatacagg atctaaacaa cctttttctc
     9901 tttcgcaaac aaaaaacgac agcaaccaac cataaggtag cactgtccat tttgttactc
     9961 ttatacaatt atggaacaaa gccaactact actctacgcc tcattgcttg attgtagttg
    10021 gggcggcatt tacacatgct acatcttggc tatattttgt atttttataa aaatcatcga
    10081 tatttattaa tggaagccaa tataatgggt tatctttcaa tatcccctct aaagctagta
    10141 taataccaga actccctgtt tgaaagtcat cagacaaacg ataacaaaac tggcctggaa
    10201 ataaaatatg attttcctta ggaattaaaa ataaacgtaa caattctatt acacaatctt
    10261 ttttgtttgt gtactcagaa tcactttttc ctagtagagg cggtattatc aaaaagcttc
    10321 cagcgccatc gtaaagcccc ccgcttaagc tacatctaac acgatataaa ttagtaatta
    10381 agctcaattc tctttggtaa cgttttttat cactaacatg atttaggtat acgattgcta
    10441 ttcctatacc taacgatccc cctgaaaggt aaggtaataa gcgattggag tcatcaatcg
    10501 tttgcaatgt gcttttgtct tcttttgttt tttctaaatc tttatcaatg cattcgatag
    10561 atttcaagta ataattttcc tttttggtga ctgcatacaa agccgagtaa aacaacgaga
    10621 ctccagacca accatccatt ataccgattg gaatcccggc ccaatcctga acttttaact
    10681 ctttcttctc gctcataaaa gtatcaatga tactcgcgac aaatattgct ttgtccagaa
    10741 aacgttcatc tttttcttct aaataaagac taacgaaccc aagacctata cctgacaatc
    10801 ctgaccttaa agatatatca gacgaattaa gattcatgtt tgcaaagatg ttcattgctt
    10861 cttttttata accgatttca tataatgttg tccctatgcc tgctttacct gttaataatc
    10921 caccttgttc aatagaatcg atgtttctca ttaattcatt ttcaatccaa tggtttatat
    10981 tctcactcac agtaccagat ctaaaaaatg ctagcgcagc tccagtgcct ccattttgta
    11041 cattgtattt cccagctttg ctttcatatt gcctgatatc accatgaatt aatttttcgc
    11101 tacgaacaaa atttttctca ataccgtttc tgagaccttc tataatggag gaaacatcct
    11161 ttttcatcgc atttttattt atggcatgcg acctattctc ttctcctata aatgataaat
    11221 gctgattaca tttttccctt atcattttta caaatagcag aaaatcctct ccataaactt
    11281 tttcaatcca ttgatcttga taatcataca tatcagaatc aatatcctcg attggtccaa
    11341 ttggcaataa gcaatgtcgt aggattttct ttattgcata ccaatccctc tctccgttat
    11401 ttttattacg tggatgagag aatccgtatg tttgcagtgt aggctttcct tcagaatcct
    11461 taggtcgtgc tgtttcaaag tcaatcagag tcacgtttaa atcttcggat atgatgatat
    11521 ttgctggttg taaatctccc attcctacac catttttatg catttcttca acaatagaca
    11581 ccaatttagt aagaatatta tgtattttgt tcttatagac tttgatatca ccattattaa
    11641 taaaagggta gttcgctaca atccaggaat ctaagtcaat tccatccaca tactcttcca
    11701 caagaaaact atgtttccaa tgtgtaaagt aatccagtat atttacaatt ccatctactt
    11761 tcgatagctt tgataaagca tcaagttcga ttttttgtct ttctaatgca tcaacttttt
    11821 gaccatccaa tcctgatttt ggccttgctt ctttaataat gactttcttt ttatctttct
    11881 tcctttctgt cacatagatt cctccaccat tcgtaaagcg aagtgcactt tgaaattcgt
    11941 attcttcaaa tttattattt tctacatcag cctcaataga tgtggtattt aaagaatcta
    12001 aatactgatc aaattcttta acaaaagtag gtactttata gtaaggaacc ctttcgtcta
    12061 caagcaattc accattttca tctttcatgc acaattcgcc ttgttcgttg aatatcattg
    12121 caaatccgcc atacctatag taaacattgc tgtttttcca acacttgtca ctcaggatgt
    12181 atggaccact ctcaaaagaa tgaagagtgg tatatagtag atctaataaa tttaaaaaat
    12241 catcgtcact aggaggatag atcgtaataa actttcccga acttgctcta tttgcggtct
    12301 ttgagtttgt agtaaaataa tcccattcgc ttgcaagatg tttgaaatgg actttacgtt
    12361 caaccaatat atgactgacc ttctgtaaaa tctgttctgc attatcaagt gttgcactaa
    12421 tatggatttt ccaaccttga gcttgcaagg atcgttcttt aaacttgtac attttccata
    12481 cagaattttc ttccctgctc actacacaat catctgataa atttgtcaca ttaaattctc
    12541 tctcagtaac gattgatttg ttaggagtga aatatttcga gttttcattt aaataatcat
    12601 aataaaccat gtttgccttc atgatatact ctcctctcat aaatgattta tgtacctctc
    12661 ccaataattt gtaagctaca tcttatgtat tcgtctcatt caaaaggacc tagttgaagt
    12721 tagccttcaa ctaggtcttc tctgaagaag cactttacaa ccattacccc catggccaag
    12781 ggcaaatgtt actatacaat gaccacctag cagctacttc acttgcctcg ttttgaggaa
    12841 gtttttgtaa attcagtact tgattcatta taattcacct ccttccaaaa tttagttcaa
    12901 atgtcgtgac tattattttt caaatctata aagcttgtac tatattaatg ctccggtctt
    12961 catcgcgaac taaaattcta accaccttta aatcgaattc atattacata ttttaacaat
    13021 aggtggatat tattgtcaaa taaattcgga acttgcgata gattcagtaa atttctcaag
    13081 tagctgatgg taccagattc ttggagagtc acctctactg agtttttcat cttttatttg
    13141 ggcaagagaa gcctacgaaa aaagtagact acaagaaata gttgatgtag tctactttct
    13201 ctttcaaact caacgcttaa cgcgaaatcg ttgtatgagc cagctcctcc gtcacggtgc
    13261 aaaccgcact cgaatcccag ctacctttgc cttgtgcttt cgctgcctca tacatttgcg
    13321 caaccgtgcc tccaacgaga acaggtactt gctgttcacg tgcggtttgc gcatagagct
    13381 gcaaatcttt gtgcatatga tccaaagaaa agaccgtatt ttcatacgta ccatacaaga
    13441 tgttaggccc aaatacggag agcacacgat tgtgggcaga gcctttgtcc atgacggctg
    13501 ccagcttgtg cggatcaacg cctgcttttg ccccgacagt aaacgcctcg cccaacgctg
    13561 ctgtaatgac tgcaacgaca gaattgtgac aaagcttcgc cacttgtgca gagccggatt
    13621 cccccagata aaaaatttcc tttccaattg ccctgagata gtccatgatt tccggaagct
    13681 tggcctcatc accgccgacc ataatggtca acgttccggc cgcagaaccc gcaggtcccc
    13741 cactcaccgg acaatcatag tagtagatcc ctttttctac gccgtgctga ttcagacgtt
    13801 ttgctgtagc aggatcgatc gtacttgtat caaatacgaa actgccagcc cctaatgata
    13861 agaaaagtcc gtccgcaccc agcatgactt cctcaacaat cgcaggacct ggaagcgaag
    13921 tgaaaacgac acgtgctacg ctacccactg cctgtggaga ctcgacgact atcgctcctc
    13981 tttccttcgc ccaggctttt gctgctggac ttgggtcata ggcatacacg tggtagcctt
    14041 tttgcaacag attgcagacc atccctttac ccattgcacc aatgccgata acaccaatcg
    14101 cttccatctt cgctcctcct gctttcccta tacttatggc cgaatataaa ccgtttttgt
    14161 ctcgacgtaa aaatcgaacg ctgactcccc ttgctctctc ggacccaatc cagatatctt
    14221 tttgccacca aacggaaact gtgattcaaa atgagtcgac ggcatattga catgcgtgac
    14281 acctgactga atgcctttga caaattggaa agctttttgc aaatcgtttg taaaaatcgt
    14341 ggatgacaag ccgaattcca cctggttcgc cacttgcata gcatgttcga aagaatccac
    14401 atcgatcacg gcgatcacag ggccaaaaat ttcttcgttg gcaatcgtca tctcctgcgt
    14461 tatgccggta aacaccgtcg gagcaacgaa gtagccctgt gcgagatcat cttctaccag
    14521 gcgcttaccc ccgcattcca gtacgccgcc ttcttccatc cccttttgca catagtgaag
    14581 atacagattg agctgatgct cgtccactac tggaccgtta tgattgtctg gatcgaaacc
    14641 attcccgatt ttcaagccct tcgcccgctc gatcagtttt gcttttactt gttcggctac
    14701 ttcgggtaca accaatacgc gactggtccc cgtacaacgt tgtccattat cgaagaatcc
    14761 actcagtacg atggaatcga tagcgaggtc gatatcagcg tccgcgagta tgatcgccgg
    14821 atttttcccg cccatctccg cctgaatctt gcctcctctg gctccaactg ctctccccaa
    14881 ggcaagtccc acttcagaag aacccgtaaa tgaaatccct ttgaccagtg gatgattcgt
    14941 taattcttcc ccgattaccg cacccggtcc tgttaccaaa ttcactacgc cactcggaac
    15001 gccgctttca atcaggagct ctaccagctt tacgctaatc aaggaggtgt tgcttgctgg
    15061 cttgaacaca accgtattgc ctgcgaggat agccgggacg atcttccaca agccaatccc
    15121 cagcggaaaa ttccatgggg caatgatcgc gaaaactccg attggctctc gcaccgtgta
    15181 accgattacc cgttcatcaa aggaaggcac cgtctgacct gtcaagcgag tggcttcccc
    15241 agtcaactgc ttcatagagg taattgtctt ggcaacctcg cctctcgctt cccgcaatgt
    15301 ttttcctact tcacgggtga tcgtttctgc gagctcttct ttgtgttttt ccaacaaatg
    15361 aatgagggaa aacaagaact ctccacgtgt gggagccgat ttttgcgacc attcaccaaa
    15421 agcattggca gcagcttcaa tggcagaacg cgcatccagc ccgtccgatt tttgaaaata
    15481 accgagaacc tcattcgtat tggcagggtt cgtgcttgga aaaacttgcc cggtatggct
    15541 cgccacccaa gctccagcga tgtagttatt gtaggttact gtcaaatcgt ctcccacctt
    15601 ccgtatctta tagaagtatt gtatatagca aaaattatga atacaatgta tacacagaca
    15661 cttatttcca actattattg tgtatttctc tacatggagg acacgtggat gaattctttt
    15721 tcgctcctgc ttgaaaagct gcataaatgg tttggcgatc agcccttttc cattttgttc
    15781 caattttcgc gtgatcgaca ttttcggctt gttttctcct cttttcatga aaacgctgcc
    15841 acgaatattc cccctatgac agttcctctc tgtgacaacg atgctagcca catgcgctat
    15901 gcatttgagt cccttccctc ccaacagatg taccgttttt tctacgaaaa cgaaggacaa
    15961 gccgttattt gccttgcaca tcaagcaaaa ctaccgatca tccttaccgc tgaccaatgg
    16021 gaactattgt ggttcgggtt tcgcctgttg ttggcggaag aaaaaatgac tgcaaaaacg
    16081 gaggaaagca agaagctttt tgaagggatt cgctccatat ctgctaccct cgacgttcac
    16141 caaatcatac gtggcatcat aggaaacgca ctagctgtta tcccggctgc tgacgcaggt
    16201 ctcctgcact tgtatgatcc cactatcgat cgattgattc cgaaagcgac ggtcggtttt
    16261 catgatacgg tgttcaagga tctcaaaatg cgggttggag aatccatcgc aggcaaagtg
    16321 ttcgaagacg gaatcccacg catgtacaaa acgagccaag aaacaaccca tgcgatgaag
    16381 gatatctctg ctgacaactt tcactctctg aaccacgcaa aagcattgcg agacttgaat
    16441 gggttgttat gtgttccgat atcacgtgaa gaaaagcgta ttggtgtact tgtcctgcat
    16501 cagtttcatc aagaaaatgt gtttaccgac tacgacctcg accttctcca aggcttcgca
    16561 gaccaaactt ccatcgccct gcaaaatgcg gagctctatg ctgaagtcaa gcaagcgtat
    16621 gaacatatgg cttccattag cgctcaactg caagccaagc acgatgattt gatacaacgc
    16681 aaccatatac atgaatccat caagcagttg tccttgcaaa ataaaggggc ggaaacaatc
    16741 gtaaaaaccc tcagcaaaat gacaggacat tccatctatt ttgccgattg gcttgagcaa
    16801 aaaatgtatc ctgaaaagag tgctgtattt tttagctggg atgaactgta tacattgctg
    16861 aataaaaaaa gacagcctgt ttcggtcaac ctgtttactc ccgcttccgg tgacgatcaa
    16921 ctgttctgtt tatatccact aatcaatggg agtatttttc tcggatgtct catgattccc
    16981 ttagacgaac gggggctttc tgatctcgca cgtatgacgg tcgaacaagg gagtgctgtg
    17041 ctcatactcg atttggtgaa aaagcaatcg atcagctccg tgctgtataa gcgagcacac
    17101 gatctttttc aagagctgat cgcaagcaaa ggaaatgaac tgtttgaccg cgcccgttcg
    17161 atggggttac agccgcaagc agagtactac gtgatttatg cccatttgac acagtgccac
    17221 gacctggcat tgctagaagc aaacattcac cggctcatta cccgttggaa atgggagttc
    17281 agtaagacac agatgcttgt atacggattc cataaccatg tcaccctcct catccggtct
    17341 ctcggctccc gagatggaaa ggacatccgg gagaggctgc aacaggcgtc cgatgagtgg
    17401 gaacttggca aggaagcatc gttatccatt ggcgtgggaa gcatggcaag cgggattgag
    17461 caaattagca aaagctacga agaagccaaa aaagccgcac attatttgac caaccgtggc
    17521 cgttctggtg tggtttacta taaagacctg ggtgtcaatc gcctcatgct gaatcagagc
    17581 caggccgata ttgatgcatt tattcaagat gtctttgccc ctttctggca agacccggaa
    17641 aaatatcagg aatgggaaca gacgatcata acttatatga aatgcagtca atcccctcaa
    17701 ctgaccgcca aagaactgca cattcacgtc aatacgctgt atcaacgttt gcgcaaagta
    17761 gaggagcttc ttcatatcga tttacgaaat ccggaagact tgctgaaatt acagctcgct
    17821 tgtcatttgc gccaggaagg ttaaatcgaa aaagacagga gtagcttcgg acaggaaaaa
    17881 gccccaggct accactgcct tttttgttta ccataattaa gttatgtaaa tcagtttcct
    17941 tgtgtatttt ctctttgtaa aaattggaaa tcatccataa tgaacatggg ggctccaggc
    18001 accaaacacc ccagagattc acgccctact acttgtaaag gagtgatgat gttttggatt
    18061 cgcaaaaaca aatagaaaag catatgagag gttccaaacg ataacttcat cccttctctc
    18121 atatgctatg ggaggaaatg aacgaaatgt ttgctcaaaa aatggttcaa ggaacggaac
    18181 tcacaaccga ttgcttccat agcgcgacca atctgttcga agcgttgaag catcatgtat
    18241 ccatcaaagg ggtcattgca ggtgtgattc ctggtagagt attcctgtca aatgacgcga
    18301 gatcagcctt gctgacaagt cctcaaggta tttttctagg aggcagtgtt gataatcccc
    18361 tcttctttaa agaagtgaat acattgctaa aagaggagct attaccgcag cttgctgctg
    18421 atgaacagct tgactacgtc ctgttttatc ctacggatga gaagtgggat gacattctcg
    18481 atatcgtaat gaaagatgta ttccccatga gaagcggccg aatgatcttt acgcaccatt
    18541 tagaggatct gtcccctctt gctgacgacc atattttccc gataaacagc accttgttga
    18601 agcggaaaga attggtaggt cttgaggatg ttatcgatga aatagcagag aattggccat
    18661 ccatagaagc ctatgaaaac aaaggcttcg gttgtgccgc gatacaagat accgatgagg
    18721 ggccgccaaa caacgcggga tgaaaagagt gggatggcag tgctggtcaa ataatatagg
    18781 atcgcagcga acagccttgt ctgtcggttt cgagctgctc gcggatttcc cggttctgtt
    18841 cggatggaac cttccgttaa acaatttcct tgtcaacggc aaccactata tgcgtggcga
    18901 tctgaaatat ggcgtggaaa aagactatgc ccgcgccgca tggagttatg cccaagcact
    18961 tgatgaaggc tgggattgga atggcgatgc ggccttgtat tggaatgctg cttgcctatt
    19021 ctatctgagt ggtgaagagg accgggcaaa gcattactat aaaaaggcta tcgagcacgg
    19081 ctgggtaagt attcatcacc cgcattatca tgatgatgtg tacagggaac aggacagcga
    19141 gcagatcgct cgaattcttg ctgaatcact caaataagtg aaacggccgc cgttttttcg
    19201 gcggcttttt gctgagctca acttttccct ctccttctct gcctttgaag gaaaaagaaa
    19261 tggtttgccg ttcaagtagt ttttgatcat tggtattgca tagggctgct cttcttttaa
    19321 cccctcggtt tccctgtggt caggagcatg atgactataa ttttcatcat gaccatcact
    19381 gtgaagctct ctaggatggg gagccattcc ccttctaggt tccgcaagct cttgtagcct
    19441 tttatgtcta gcgctctttg ttcaggatat aaccccaaaa tggtatggct tggtgcagat
    19501 tgccgtgaat gacaccatag ttgctgctgt tcatgtccaa tttagcaaga caagtgagta
    19561 ttttatccgc cgccaattga tatagcacga attcttcatc tgtcagaaac tgctggtaat
    19621 gctccctcaa acgagacata gattgcttga agctatcctc tccccaaatc ggacgcgcaa
    19681 attcaggggg caattggaaa tcctgagata cagtatgaag ctttgctaat aagacaccct
    19741 ctttgtacac ttggtcttcg gtaatttttt catctgcatg ctccccatcc aagtcgtatt
    19801 cttgcagcgc cttttgtgcg atttgctggg actgggccac taccttctcg atgtcatctt
    19861 cagaattcaa ctgaaatagc ttcgtcatgc gaatcccccc acccaataaa tggatcattc
    19921 gcttacattc gtttgatttc ggccgtactt cctcttttta tttttttctc ttgactccaa
    19981 cctaaggtca gactgcaaac tcaacttcag gaggtgaatc gccatgttgt ataccgttaa
    20041 cgatgtagcc aaactgtctg gtaccacaat caagacactg taccactatc aaaagattgg
    20101 tttgctgatg ccagaaatcg ttacagaaaa tgggtaccgc tattacggtg agaacgaact
    20161 caagcggtta caacaaatct tgttttatcg tgagcttgat ttgtcattgg acagtattaa
    20221 agctgcactt gatcacgaac cagacagact tcgttgctta tgtgagcagc aaacgatgct
    20281 aaaggcacgc cagctacgat tggagcgcat tttgaatact ctcgaagaaa cgattcaaca
    20341 cgaaaggaag cgaggaaata tgtccacaga aaacatgttt gatggattga acgaagaaga
    20401 atggaagcag gcattcactc aacaaaatga gcatttgcag aaagcgtacg attttcaatt
    20461 cgatacagag aatctggacg tgacttccct gaatgaaaaa gctgccgaag cgaaggcttt
    20521 catgacgttt atggcagacg cgctgaaaaa caacagaagt gtcgacgata aaacagtggt
    20581 ttctgcgatc gaaagccatc ttgctttttt acaaaaagac catccgattg atgcgaaagc
    20641 ttttgccgag cagtcaagat ttttcctatc agatgagttc caccgcacta tgttggaaga
    20701 acagcaaacg ggattaagct actacatttg cattgctgcc gaaaattacg cttccaagta
    20761 aagtgtagtt aaacgattgt ttaacagtga aaccgggtga gctgcaactc cccggttcat
    20821 tgtttcaatt cctatctaat gccttagatt accgccccga taatatgctc cttgatcagc
    20881 atccatcgat cacgaggatt cggcatgaat tccgatgcaa tggctacgac gaggtttttt
    20941 tccgggatgc aacagataac attaccgcca tcgcctattg cagcgtatgc aaaaacaccg
    21001 tcctcttcac gcaaccacca tagatacccg tattgattgg gattcatagc gattgattca
    21061 tctatccaag cctctggaat gatctgatga ttgtcccaac agccacgatt caaatagagc
    21121 caaccaaaac gtgccatgtc acggggagtt aacgtgagac cccatcctcc tgtggagttg
    21181 ttgtctggat cttttaccca tcctctcaca tctttcccga ataaatcatc agacgcaaac
    21241 cacttcattt cataatcagg gatttcttcc atgccgatgg gtgtaaacaa gcgttcgttc
    21301 gcgaattctc gggcactttt tcctgtgctg cgtgtgagga tggcggagag caaatgcgcc
    21361 ccagcggtcg aatacttaaa cgctccaatc gttccctttt gcccgagcat atccagcgta
    21421 tatttgaccc aatcggactg catacacatc ttgtccagag gttcgtgcca gtcctcaaaa
    21481 ggataggggg ctgtcatcgt gaggagatgg cgtatggtga ttgcttgttt ttgctcatca
    21541 gtatgatcgg gtgcatagtc tgggaaaaat tccagcacct tttggtcgac atttttgata
    21601 aaccgttcct ctaaggcaat accaatgagg gcagatagaa tacttttcgt tactgacgct
    21661 acatggtttc tatccttcgg tccatagcca tgatagtatt tttcatgtgc gagatagcca
    21721 tttctcacaa caacgattcc gtttatgttg ctgtacgcgg attttatgat agggtctagt
    21781 tctgctagtt tttcagcgtc aatgttcaag atggccgggt ctgctgcttg ccattctgta
    21841 gtgggccaat agcttctttg catgataatt ccctcctcca caaggtaatg tcattttttt
    21901 ctgactgaaa aaaacacctc cgtaacaagc tcctcaggaa cgctggcttg atcgggtgcg
    21961 gttacataga cttcgtaggg tgatctcacc aattcatagc cttcattttc tacccattcc
    22021 ctcagcctgg catataccga tatcaattct gagtaaggac ccttacatac agactttgca
    22081 caaagtcccc caggcaaatc tcttgttccc tttacagcct ccgcgaccgg gagtgcaaac
    22141 tcggtatcgt ttccggcagg attaaattca gggctgtgat aaatcgtcat tggcgtgccg
    22201 agcaaggtga gcttttcagt cgcaatcctt tcatacagct tactaaaata cttgccatat
    22261 cctgttgcat aatcatcact cgtcatcatc tggcgtaacg aaagaatatg gatgggctgg
    22321 gtctccacaa gctgtacttc tatgttgtca aggtatgcca tcatagggat accctgctcc
    22381 attttcgaaa gatcatggtt cagttgtttt atggtatagt ccaaagcatt tcgtttttca
    22441 tgcatttccc tttgtttgcg aagaagcgcc gaaacaagct tctcttccga ttgatcttct
    22501 tcccattcca ggatggcttt tatttcgtcc agcgaaaaat gatacgattt caaacggttg
    22561 atgaagagca tctttttcag ttgcttgatg gaataatacc gatagccatt ttccggatta
    22621 at
//
