LOCUS       NZ_CP018145            24526 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Brevibacillus formosus strain NF2 chromosome, complete genome.
ACCESSION   NZ_CP018145
VERSION     NZ_CP018145.1
KEYWORDS    RefSeq.
SOURCE      Brevibacillus formosus
  ORGANISM  Brevibacillus formosus
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Brevibacillus.
REFERENCE   1  (bases 1 to 6437015)
  AUTHORS   Fu,B. and Li,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2016) Insitute of Enzyme Engineering, Shaanxi
            Academy of Sciences, No 16, East Renmin Road, Xi'an, Shaanxi 710600,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3
            Genome Coverage                   :: 167.68
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 02:46:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,168
            CDSs (total)                      :: 5,986
            Genes (coding)                    :: 5,821
            CDSs (with protein)               :: 5,821
            Genes (RNA)                       :: 182
            rRNAs                             :: 16, 17, 17 (5S, 16S, 23S)
            complete rRNAs                    :: 16, 17, 17 (5S, 16S, 23S)
            tRNAs                             :: 127
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 165
            CDSs (without protein)            :: 165
            Pseudo Genes (ambiguous residues) :: 0 of 165
            Pseudo Genes (frameshifted)       :: 85 of 165
            Pseudo Genes (incomplete)         :: 95 of 165
            Pseudo Genes (internal stop)      :: 22 of 165
            Pseudo Genes (multiple problems)  :: 35 of 165
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:35:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 737484
            Orig. end                         :: 762010
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP018145.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24526
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24526
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24526
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14526](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14526)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    429..442
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.16"
                     /tool="antismash"
     gene            908..1129
                     /locus_tag="BP422_RS03730"
                     /old_locus_tag="BP422_03650"
     CDS             908..1129
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390719.2"
                     /locus_tag="BP422_RS03730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03650"
                     /product="response regulator transcription factor"
                     /protein_id="WP_003387736.1"
                     /transl_table=11
                     /translation="MKGSDQTKPLLTNREREVFELLVQDKTTKEIAGQLFISEKTVRNH
                     ISNVMQKLGVKGRSQAVVELVRLGELEI"
     gene            complement(1502..2251)
                     /locus_tag="BP422_RS03740"
                     /old_locus_tag="BP422_03660"
     CDS             complement(1502..2251)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019450.4"
                     /locus_tag="BP422_RS03740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03660"
                     /product="stalk domain-containing protein"
                     /protein_id="WP_088906611.1"
                     /transl_table=11
                     /translation="MNKSQKLFIGVVSGVLLFTAGMMSSGSAFAKKATEAITVNFSNIK
                     LIVNGSPIDTKAEPFVYKGNVYAPVATIANMLGVGQSWMNSDPLTKTPAVRFESLDRVE
                     QNVQFEGMAGHANYALDYVYYAVVGSNKVVNSVNKKEIPLPQSVGGTLYPVTRMVHTNQ
                     FLAVEYGEKEGKTQVYVNLYQLDKGKNTVKIIFSQQLDEGAKGTTYRFSYNEAEKSLTE
                     RIYTNQKLVGVKFYQISGNQFVKQEEM"
     gene            complement(2486..2725)
                     /locus_tag="BP422_RS03745"
     CDS             complement(2486..2725)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006637748.1"
                     /locus_tag="BP422_RS03745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YciI family protein"
                     /protein_id="WP_088910864.1"
                     /transl_table=11
                     /translation="MITTRTPNFNINDITGHYEHLEHLKKNGRLESYGPFSDSTGGAYL
                     IKAESLEEAVLIGDSDPLIRSGSSTVTVKEWLTK"
     gene            2844..3098
                     /locus_tag="BP422_RS03750"
                     /old_locus_tag="BP422_03665"
     CDS             2844..3098
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BP422_RS03750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BP422_03665"
                     /product="hypothetical protein"
                     /protein_id="WP_088906612.1"
                     /transl_table=11
                     /translation="MTEYKIKGQSGSIEQTITLPAESPEQALEDAKKHLPERMHGQLSV
                     SSDDNEYRKLLRRNGYPERVLDQFSDEGCEGECETVGIV"
     gene            3095..3223
                     /locus_tag="BP422_RS32520"
     CDS             3095..3223
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BP422_RS32520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_257790208.1"
                     /transl_table=11
                     /translation="MTEQQIVETLGTKVMGWSKKQIDFLYPAWNPLENIADAIQSC"
     gene            3405..3632
                     /locus_tag="BP422_RS03755"
                     /old_locus_tag="BP422_03670"
     CDS             3405..3632
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BP422_RS03755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BP422_03670"
                     /product="hypothetical protein"
                     /protein_id="WP_088906613.1"
                     /transl_table=11
                     /translation="MKAYRVYYDTAGRSANMIVLADDESKLEEAVANKDKKFKQGDTRS
                     KITLSEEIPLSNVLIAQLSVTELMQLFKPI"
     gene            complement(3748..4389)
                     /locus_tag="BP422_RS03760"
                     /old_locus_tag="BP422_03675"
     CDS             complement(3748..4389)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BP422_RS03760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BP422_03675"
                     /product="hypothetical protein"
                     /protein_id="WP_088906614.1"
                     /transl_table=11
                     /translation="MQKIVVSLLAVLLSITSTAYASPQNDSPVHYPSSPVIIPKEYQVF
                     GLDMDSGFIDTFGHIEDDLYLLQRHQKAADTTYAFLGKKNGKVIKIDAMQYGPNSGNVY
                     FGVLDSDKDKNGNLYLLVYYSIDKTNSDGSVDLEYIQVSSLKYQQGSLVEVDKLITKKL
                     PDKHTLDFSYGGLKLWASVLDNTSGEEKLVITDLYKWDFKTHKIIPISNK"
     gene            5279..5416
                     /locus_tag="BP422_RS30915"
     CDS             5279..5416
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BP422_RS30915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157696730.1"
                     /transl_table=11
                     /translation="MILYPTLTAVQEKLHDAKQVHMSQLVGQLQIIGTIYEDPELLETT
                     "
     gene            5481..5774
                     /locus_tag="BP422_RS03765"
                     /old_locus_tag="BP422_03680"
     CDS             5481..5774
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006097360.1"
                     /locus_tag="BP422_RS03765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03680"
                     /product="barstar family protein"
                     /protein_id="WP_236841282.1"
                     /transl_table=11
                     /translation="MRDERVFRITIDVSNVKSNEDLHSLLKSSLNFPDFYVMNMSAFWD
                     AITGLVEMPINLTFIGWDSLKELLPDVTATFEKTLEQYNDYYPNHACNVIYS"
     gene            5822..6061
                     /locus_tag="BP422_RS03770"
                     /old_locus_tag="BP422_03685"
     CDS             5822..6061
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966861.1"
                     /locus_tag="BP422_RS03770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03685"
                     /product="DUF1653 domain-containing protein"
                     /protein_id="WP_088906615.1"
                     /transl_table=11
                     /translation="MRDLQFQIQQHSLYRHYKGKLYYVMGLAEHSETNELMVVYHALYG
                     DNEMWVRPLEMFLSEVEESKENPTGQKYRFELVQ"
     gene            6253..6474
                     /locus_tag="BP422_RS03775"
                     /old_locus_tag="BP422_03690"
     CDS             6253..6474
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589024.1"
                     /locus_tag="BP422_RS03775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03690"
                     /product="response regulator transcription factor"
                     /protein_id="WP_003387736.1"
                     /transl_table=11
                     /translation="MKGSDQTKPLLTNREREVFELLVQDKTTKEIAGQLFISEKTVRNH
                     ISNVMQKLGVKGRSQAVVELVRLGELEI"
     gene            complement(6983..7342)
                     /locus_tag="BP422_RS03780"
                     /old_locus_tag="BP422_03695"
     CDS             complement(6983..7342)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BP422_RS03780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BP422_03695"
                     /product="hypothetical protein"
                     /protein_id="WP_088906616.1"
                     /transl_table=11
                     /translation="MDKQKVYAAASIIESTYYKYQHTNWLNFSIKNQTIARIHIKLEIP
                     LIEAKTIYRFAIENKIPKVWYALVERAEIIEFPSRDLIPEAVRFISEDSLKEISANRLR
                     TEERISREIAELDDD"
     gene            complement(7470..7730)
                     /locus_tag="BP422_RS03785"
                     /old_locus_tag="BP422_03700"
     CDS             complement(7470..7730)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020529.4"
                     /locus_tag="BP422_RS03785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03700"
                     /product="DUF1871 family protein"
                     /protein_id="WP_157696731.1"
                     /transl_table=11
                     /translation="MIYAKVKSIIDRWDPIGLVGIDPEHDHYRIEINEIIKLLQSNYST
                     PEELAKHVESIFIEYFDDEIYNRPFAECLDVARILFTIDCD"
     gene            complement(8137..9981)
                     /locus_tag="BP422_RS03790"
                     /old_locus_tag="BP422_03705"
     CDS             complement(8137..9981)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016739435.1"
                     /locus_tag="BP422_RS03790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03705"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_088906618.1"
                     /transl_table=11
                     /translation="MYATTEDVFSLKTVIQSFRNWPKIFRLFWTVEKGYFITIVILNII
                     QGLFPVGMLYVTQELVNAVSTGVGQDWDTIAISFLLFLSFILVKQLVTLLQNYVEGLFQ
                     SLLANRLREMVLDKASTLGLADFENAEVQDQLKRAQQETSYRPYQIFVLVLSILSGGIS
                     LVSTSLFLFFWKWWVVFILILFPLISFYSYFRLSQQEFYIHWNRAERERKGWYISYLLT
                     HDRAFKEVQIYKLGPYLIKHFRDMIAQFFYEDKKIATSRLKTSLVFECLTIAMIAFMSF
                     IAIKAAFLKEILLGNLVSYLQGITLTHSTSQSLMHSLIGLSQHNMYVEQLFLFLDRDSS
                     DPVKQQKVAIPAAPRQNEPFVLESIEFVNVSFTYPETERLVLQNLSFTIKKGESLAIVG
                     ENGSGKTTLVKLLTLLYKDYEGQILINGTDLKAFDLDVIRTKIGVVFQDFMQYEMSVRN
                     NVGFGNLALLQHDDKLYHALEQSGMRSLAEGLEEGLDTQLGKWFADGLQLSGGQWQRIA
                     IARAFLRNADLYILDEPSASLDPLAEKEVFDAFNLLTKERMGIFISHRYSSAQYADRIM
                     VLDQGRIVEFGTHSELIRLQQKYASLYNLQASPFVVHS"
     gene            complement(10001..11314)
                     /locus_tag="BP422_RS03795"
                     /old_locus_tag="BP422_03710"
     CDS             complement(10001..11314)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="BP422_RS03795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03710"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_088906619.1"
                     /sec_met_domain="LANC_like (E-value: 6e-70, bitscore:
                     234.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSNTKSWQPIKDDTLVKNIEYVVKQIARKLQSPHAVLGEPLPGT
                     GSLASGALGIALFYAELDRQYPDEQWDVIAHHYLVHVQTGMNANTFHSLSLWTGLSGAP
                     VVASILARDRGRYQNFIEKLHIVMQPAIDEFIDQARERIGNNVFMPDYDVIDGLAGIGR
                     YLLSFKEHSACKKNLIKALSYTVQLTEDIQLDDRIVPGWHIKSEDQFLEIEQKQYPNGN
                     FNLGISHGIAGPFALLSLALLAGVEVAGQREAIRKLCSYYDKWKAEDEYGPIWPERISF
                     EEQICGQMRNNFAHNASWCYGEPSIARVLWLAGEALGDTQIQSLAQKVYLSLVQRSVES
                     FGFDSPTFCHGYAGALWMIQRMMMNTGSDVLAAYRETLINQLLNSFNENTAYGFQDIEL
                     GQPQDHPGLLTGAAGVALVLLSCLSLDEPEWDCMFMLK"
     gene            complement(11304..14114)
                     /locus_tag="BP422_RS03800"
                     /old_locus_tag="BP422_03715"
     CDS             complement(11304..14114)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="BP422_RS03800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03715"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_088906620.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 3.5e-161,
                     bitscore: 536.0, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.6e-12,
                     bitscore: 46.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 6.8e-38, bitscore:
                     129.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEWLLKIVQSLEGNLDVVKQLHIQTNTMYEVVGNRVSLPYITRYG
                     QKHNGYEMENASIPLNDLITLVSHKAAVPIPFMELLQTIKQSYPDTEDSRIESFLFQLV
                     QNEFLFTSLRPRLTDSSPFDQLLAVLERVTGIDELYRHLLEIRQDIIAYDQLEIGQGET
                     HFLSMLSKMKSVESSPSLLQVDLSLSTEQVTLPNSIAKDLSKAAELLWRLSPNHVGLSH
                     LAEYRDAFIERYGFEREVPLLELLDENRGLGAPATYQNPISKRSDNATSPDKINEKVLL
                     QLLSHSLLTGSTEIDLTDELIKKLEPVSPKWEHVPPSMELYVSLFAASPQAMDNGDYTV
                     HVGANTGSALAGKSFGRFADMLGESFEQNLEQINQEHQKAYPDSIVAEVVYFPRHGRAA
                     NVVLSKSKREYEILIGAPSREHHSTSIPLSDLVVGATSHSFYLKSRSMNKEIIPVTGHM
                     LNYTGSVPNVYRFLCELGMVKQRNWVPFSWGSFRHAPVLPRLRYGKIILAPATWNVDQE
                     LLSVSKKDGKERWMEAVQNWIRHYNVPDYVYITEYDNKMLLDLKNQRHLAELIRELQKR
                     NSGETLVLTEVGAELKDCVVHGKDGAFHMECVFPLVKNTPEEATAIDSVSVENGVQSNR
                     VLISDLERFKMPGSDWLFYKLYCDETRVDEFIAFPLKSLCEAMRTQGACQKVFFMRYAD
                     PKPHIRLRFQAASTEGLQSIFSEMYRWMSDMQKQGYLSKATIDTYDPEIERYGGPELIS
                     LAEEIFAVDSMVVAHWLHLHRTKQLKLPLEKVAVISIIDLLHQFLHSIDEKLGFLNSLI
                     QYKAYLDDFRTDREFYLQAGRYTNGWEELKALEDGPILYQALQTRSETIQSFSTVMHSL
                     KAQSELYNSQDQIIGSIIHLHINRLLGVDREREKKVLTLARHTLHNLRYFLLQEESRTK
                     ETAHAF"
     aSDomain        complement(13770..14039)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BP422_RS03800_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="7.70E-15"
                     /identifier="RREFam001.1"
                     /label="BP422_RS03800"
                     /locus_tag="BP422_RS03800"
                     /protein_end="115"
                     /protein_start="25"
                     /score="46.4"
                     /tool="antismash"
                     /translation="NTMYEVVGNRVSLPYITRYGQKHNGYEMENASIPLNDLITLVSHK
                     AAVPIPFMELLQTIKQSYPDTEDSRIESFLFQLVQNEFLFTSLRP"
     gene            complement(14116..14526)
                     /locus_tag="BP422_RS03805"
                     /old_locus_tag="BP422_03720"
     CDS             complement(14116..14526)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="BP422_RS03805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03720"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_088906621.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 5.8e-19, bitscore:
                     66.1, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERPLHVKNHAKKESRSFFRTMDFFMLRTPLLPIHMFLELCQSDW
                     RLDKLDPRKQAIIRECIAVASPSLLESLNKLDQADREQLEQAARSCLRYGIRMSTRATP
                     FGLFSGIACGHFDTHTQLIVNKIEQHKKTEPP"
     misc_feature    14878..14895
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: strong, score: 20.62"
                     /tool="antismash"
     misc_feature    15413..15426
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.17"
                     /tool="antismash"
     gene            15753..16787
                     /locus_tag="BP422_RS03820"
                     /old_locus_tag="BP422_03735"
     CDS             15753..16787
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017251121.1"
                     /locus_tag="BP422_RS03820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03735"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_236841283.1"
                     /transl_table=11
                     /translation="MFGKLSQEYKQDPRRRLPQGALVLDQVGQFPILPRLYEPLKADGI
                     DLNNYPKALVDLYTYDGQNYALPKDFDTIGLWYNKKLFDDAKVPYPDETWDWNKLKEVA
                     KQLTDEKKGVWGIAAPPYGQDGFYNTIFQNGGYIISEDKKTSGYDKPETIEGLKFWTDL
                     INEKASPTAAQLSETEATQLFESGKIAMMYNGSWMASAFHKNEYTKDKVDVTYLPKGKE
                     NTSVIHGLGNVISANTKHPKEAWEFVKFLGSKEGAEILAKSGAAIPAFNGTQNTLVQSM
                     PNFNLKIFIDQAAVAKPYPISKDTAKWAKLETELMTKAWAGQMSVEDASKELAQKMNEM
                     LSQE"
     misc_feature    complement(16816..16830)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 17.37"
                     /tool="antismash"
     gene            16859..17818
                     /locus_tag="BP422_RS03825"
                     /old_locus_tag="BP422_03740"
     CDS             16859..17818
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012685432.1"
                     /locus_tag="BP422_RS03825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03740"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_088906623.1"
                     /transl_table=11
                     /translation="MNAMSSQLQPEMHAAVQPKTKKSLNRMKRSDWFWAYLMIAPTLIG
                     LGVFYLWPIVQTIYLSFTKWGGFGKYKWAGLHNYELLFKDPYLWIALKNTLIYTVIAVP
                     VGIAISIFIAVLLNRKIKGIAIYRTLYFLPVVTIAAAVAMVWRWLYNADYGLINYLLGL
                     IGIEGPRWISDPAIALYAVIIVAVWSSIGYNMVIFLAGLQGIPRSYYEAAEIDGAGPVR
                     MFFKITLPLLTPSIFFVSITSLIGAFQVFDLIYLMLGSKMGNPATEQTQTMAYLFFTNG
                     FESGNGGYAAAVAVVLLVMILIVTAIQMKLQKKWVHYD"
     gene            17849..18691
                     /locus_tag="BP422_RS03830"
                     /old_locus_tag="BP422_03745"
     CDS             17849..18691
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005833825.1"
                     /locus_tag="BP422_RS03830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03745"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_088906624.1"
                     /transl_table=11
                     /translation="MSVYTSRNKIGKKLLIHLLLIAGALVMIAPFVWMVLTSLKSLGES
                     TQVPPVILPTKYQWENYTHIFEMLPFLDFYWNTVITTVAKVIGQVFLCSLAAYAFARIE
                     FPGRNALFILFLTVLMVPGQVFLLPQFMIMKELGWLNTLTALIVPGLFSAFGTFLLRQF
                     FMSLPKELEEAAKLDGCNHFQIYWRIMLPLAKPGLIALAIFVALWSWNDLMWPLIVNST
                     PDKMPLSAGLAYLTGEHTNLTNYPILMAGSVLAIWPMIIVFIFLQKHFVEGITLTGSK"
     gene            18720..19709
                     /locus_tag="BP422_RS03835"
                     /old_locus_tag="BP422_03750"
     CDS             18720..19709
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012685434.1"
                     /locus_tag="BP422_RS03835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03750"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_088906625.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.9e-30, bitscore:
                     104.4, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 2.6e-24,
                     bitscore: 84.1, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHHVLVIGAGTMGTVHAKSYAAMENVKLVGIVDIRSERGKELAAE
                     TKTEWFENYEEALEKLAQVDIVDVCLPTYLHKTYVKKAADAGKHVICEKPLARDKEEAR
                     FIVDYCREKNVKLFVGHVLRFFPEYEKSRQLVNDGAIGNVGVARTFRGGIFPTAWNDWY
                     ADYKNSGSLVLDMIIHDFDFLRWCFGDVERVYAKGLLGRGFARMDYALVTLRFKNGMIA
                     HVEGSWAHEGFAMKMELAGKEGIISYDSSKEKPLVAVNRSKQAGMSGVAVPESPLRENP
                     YFRELKHFIECIDRDLEPLVTAEDAVKAVEIARAALVSIETGKPVTLV"
     gene            19723..20697
                     /locus_tag="BP422_RS03840"
                     /old_locus_tag="BP422_03755"
     CDS             19723..20697
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017251125.1"
                     /locus_tag="BP422_RS03840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03755"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_088906626.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 2.1e-29, bitscore:
                     101.1, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 8.5e-33,
                     bitscore: 111.4, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLGIISVAHMHAYSYANAVAKLDGVQLVGVADEDEVRGKAAAEK
                     FGVPFFADYHELLATDIDAVIVTSENAKHQEHTLAAAKAGKHILCEKPLATTAEAAQEM
                     IDFCREQGVILQTAFPVRFHPAVVRAKQLVEQGKVGRIMAIRGTNRGQNPGGWFVDPEK
                     SGGGAVIDHTVHVVDLMRWFMNSEVREVYAEVDSKFSDTPIDDCGILTMEFENGVFATL
                     DCSWSRNKAFPTWGDVTMEIIGTEGTISLDAFSQKLDVYSNEKGLKWVNWGDDMDSQLV
                     KDFVTSVRERKAPSITGEDGLRAVEVALAAYQSAEQKQPVVLR"
     gene            20713..21686
                     /locus_tag="BP422_RS03845"
                     /old_locus_tag="BP422_03760"
                     /pseudo=""
     CDS             20713..21686
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016739345.1"
                     /locus_tag="BP422_RS03845"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03760"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /pseudo=""
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.1e-28, bitscore:
                     98.8, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVRVGMIGVGGIGQHHLKGLLADERVKVVAVCDVNQEAAAETAE
                     RIGAHGYTSWRELVEAEKLDALFVCVPPFAHEEIEETAAAKGIHLFVEKPIGLDIQKVS
                     EKQEAIEKAGIITATGYCLRYLDIVQKRKRTWRASRLHSSAVII"
     gene            21692..22516
                     /locus_tag="BP422_RS03850"
                     /old_locus_tag="BP422_03765"
     CDS             21692..22516
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016739344.1"
                     /locus_tag="BP422_RS03850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03765"
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_088906627.1"
                     /transl_table=11
                     /translation="MAFQKGINAWCFPKETSVQEMFRQAEAHGYQGVELNLDEGDTPFH
                     LEMTEQELKGLADEARELGLELPSVSTALLWKYPLTHNEEAIREQGIRVVEKMIEAASI
                     FGSRTVLVVPGLVTAEVSYDTAYERAREALQRLAKKAEQHQVYIGVENVWNKFLLSPLE
                     MARLIDEVDSPWVGAYFDVGNVLQFGFPEQWIRILGKRIQAIHVKDFKTTTGNITGFVP
                     LLAGDIPWNRVVEALREIGYDGYIIPEISPYSQLPEQLIAHTSQALDAIFQS"
     gene            22544..23530
                     /locus_tag="BP422_RS03855"
                     /old_locus_tag="BP422_03770"
     CDS             22544..23530
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007726923.1"
                     /locus_tag="BP422_RS03855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03770"
                     /product="ROK family protein"
                     /protein_id="WP_088906628.1"
                     /transl_table=11
                     /translation="MNQDKPYAIGIDLGGTKIMAAIVDQHGKILSQANAATQTEEAAQV
                     VICRIGDLVQTVLDESGINLSRIRGIGIATAGIIDTQREMVIFASNLNWSDVPIGAMLQ
                     ERFGVAVQLINDANAAAVAEWAFGSARGTKDLIYVTVSTGVGAGIISGGRLITGVGDSA
                     GEFGHISLDPEGPLCACGNRGCLENYSSGLALASRAREQLLQGVTSSLLVENGNDLSRI
                     TAREVGEAAVRGDLLSMTLMKEAGYYLGVGLTNLIHLFNPQVIVIGGGVMKNGQLLLAE
                     AKNVIRERSISRMANQASIQLTTIGAEAGVLGAAGMYYPSEREVVEV"
     gene            23694..24512
                     /locus_tag="BP422_RS03860"
                     /old_locus_tag="BP422_03775"
     CDS             23694..24512
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012685439.1"
                     /locus_tag="BP422_RS03860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BP422_03775"
                     /product="hypothetical protein"
                     /protein_id="WP_088906629.1"
                     /transl_table=11
                     /translation="MADAKTAKAAKKPGFFKELLTFLLVVAIILGIASGAIFYLSGKNL
                     DDLLGSRPVAKKETNQPAPVSPVSTGQEAGTNQKANAVPVSSEENDATEEAMPVGYPVD
                     TQGQQSNAVGQVAQPALPTQKGSLKGTITWQYNDFVGTKPDVNAKIFLIRKDFNINTIT
                     DMEEKLFISIEAAPKGSGLYTAKANGYGNYEIGNVPVGEYYIIVVSGKTHRDIRQPVDE
                     YFTSIFTPYVRNWEDFTLLSLGTNKYEFSPITIEENQTLDFSHDFGYTFY"
ORIGIN
        1 acgtttacgc tcgtgttgct tttcattgga cttgtctctg tccttggaac accttctgta
       61 gcttcttctg tgcgtcaaaa ggccgaacaa attaaagaat cccaatacgt cttggctgcc
      121 atttcactgg gggctggccg gaatcaaatc gtctttcgcc acatcttgcc acatttgaag
      181 gaacagctca tgattatctt ggtgacagaa atgatcgctg ccatgacctt gatggggctt
      241 ctcggcatat ttgacatgtt tgtaggtggt acgaaaatga ccttcgatcc cgttctgtat
      301 cattccatta cacacgaatg ggcagggctg ctcgggtctt atcgaggctt tatttacagt
      361 aactatacgt ggatttttct cgtaccactg ggggcattca tgatcgccat cggatcgttt
      421 agcttgttgg caaaaggttt gcgtgataag ttcgaacaaa cgtataatcg tacccctttt
      481 atttaagttg tggtgccctt gatttttaca aatcaagggc atttttggtt gatccggtta
      541 aaaatagtgg aatggaagtc ggattgtagg gagcagtata tgtgtcgggt gaatagactg
      601 gagtgtcggg ggcggtgttg gccttgggtt ccgatggcaa tctcatcagg cgaggcgaac
      661 tcgtcgcgat ctgaatgggg gacaactggc ggccatcgtc gtctcgaacg aaaaaattca
      721 cggcggatgt cgaagaggtt tctcagcggt gttcggaacc cattgcccat tttctgaata
      781 ggatataagg caaaagccta aaatccttga aattccggca ccatcaccca ccccccatca
      841 taggataagg tgactctgta atccctcaac cttgttcctg tagagcccac aaggaggggt
      901 ggcacgattg aagggtagcg accaaaccaa gccgttgtta acgaatcgcg aaagagaagt
      961 gtttgaactc ttggtccaag ataagacaac caaagagatt gccggacaac tcttcatcag
     1021 cgaaaagact gtgcgcaatc acattagtaa tgtcatgcaa aaattaggtg tcaaaggtcg
     1081 atctcaggca gtagtcgaac tcgttcgact tggtgaacta gagatttgaa cccagtccac
     1141 ccagcctccc ttttcttccc ttggtcggaa gggagggttt ttttatgttc atttgcgtcc
     1201 cgaaacccaa gcaactttgc aaaaaagtga gtatggcgaa cagagtaata agctgtttca
     1261 ggattatcta aatgaatgga ctaagacaaa atggaacctg ggcgagcaaa cgatcgaaca
     1321 atttctgaaa aaacaagata tgcaagccga tattgggttg ctgtctattt gacggtaatg
     1381 actggcatga gaccgtgcgg cgtgttgggt tagaaagatg aagccctcta ccggcattta
     1441 atccgaaaga gggcttcaat cagagtcctt gtagaaggtt ctcttgttaa caatttttcg
     1501 gttacatttc ttcctgtttg acaaattgat ttccggaaat ctggtaaaac ttcaccccaa
     1561 caagtttttg attcgtataa atcctttcag tcaagctctt ttcggcctcg ttgtaggaga
     1621 agcggtaggt ggtaccttta gccccttcgt ccagttgttg ggagaagatt attttcactg
     1681 tgtttttccc tttgtctagc tggtacaggt taacataaac ctgagttttg ccttcttttt
     1741 ctccatactc gaccgcgagg aactgattgg tatgaaccat tcttgtcact ggatatagag
     1801 tacctcctac actttgagga agcgggattt cttttttgtt gactgaattg acgaccttat
     1861 tggaaccgac cacggcatag tacacatagt ccagcgcgta gttggcgtga cccgccattc
     1921 cctcaaactg aacattttgt tcaactctgt ccaaactttc aaatcgaaca gctggggttt
     1981 ttgttagggg atcgctgttc atccaggatt gaccgacgcc gagcatattc gcgattgtgg
     2041 cgaccggggc atatacgttc cctttataaa cgaaaggctc cgccttggta tcgatgggac
     2101 tgccatttac gatcagtttg atattagaga agttcacagt gatcgcttca gttgcttttt
     2161 tagcgaaagc ggagccgctt gacatcattc ccgcagtgaa caggagtacc cctgatacca
     2221 ctccgataaa cagtttctgt gatttgttca tgttgtttgt ctccttatga aaataaactt
     2281 ttgattgcac atttatttaa cgcaagtagg attggaaaag tttcacttca gatcgtattg
     2341 cttgcccttc ctttttcatt ctggttgtgt gtagtgtgat gcacatgtcg caaattttaa
     2401 gcaatatatc tccggagtaa atgatttatc actatgtata aaaggaaaaa cgctcactga
     2461 aggcgttata aaaggaagac gacctttatt tagttagcca ttcctttacc gtcactgtag
     2521 aagaacctga tcggattaac gggtcagagt cgccaattaa aacggcttct tctagtgact
     2581 cagcctttat tagatatgct ccaccagtgg aatcgctgaa gggaccgtat gattccaaac
     2641 gaccattctt ctttaaatgt tcaagatgtt cgtaatggcc agtaatgtcg ttgatattga
     2701 agtttggcgt tcgagtggta atgatcaaat aacggttcgt gtttttctcc ttttatgcca
     2761 gtattacgat attttaccat agtttttcga agttgtctgt tagatagcca aattattctt
     2821 actagtaagg gaggcaaata gccatgactg aatacaagat caagggacaa tcaggaagta
     2881 tcgaacagac aattacccta ccagcggaat cgccagaaca ggcgttggag gacgcgaaga
     2941 aacacttacc agaacgtatg catggtcaac tgtctgttag ttcagatgat aacgaatacc
     3001 gaaaattgct tcggagaaac ggctacccag agcgggttct ggatcagttc agtgacgagg
     3061 gctgcgaagg cgaatgcgag acggtgggga tagtatgacc gagcagcaga tcgttgaaac
     3121 gctgggaacg aaggtgatgg ggtggagtaa gaaacaaatt gatttcttgt atccagcgtg
     3181 gaacccactt gaaaacatag ccgatgcgat ccaaagttgc tgaaaaactg tttggagaag
     3241 aatatcacat ctctaaacac gatagtcagt attggtttag ggcttacgtc tccaaaagag
     3301 aaatagaggt tacacacgtg gagtcgatca aagctgcgat tgttgacgct gcatgtcagg
     3361 tggtagttta acacatcggt aattgtagaa aggggagtgc tctcgtgaaa gcatatagag
     3421 tttattacga cactgccgga agatccgcga acatgattgt gttagcagat gatgaatcga
     3481 agctcgaaga ggcagtagcc aataaagaca agaaattcaa acaaggggac acacggtcaa
     3541 agattacgct gagtgaagaa ataccactat cgaatgtatt gattgctcaa ctttcagtga
     3601 cggaactcat gcaactattt aagccaattt aacacaacac acgatttgtt aaatggggag
     3661 gcgagtttgt ccagaacaat gaaaacggtg tgccctttgg aaacagagac acaccggatg
     3721 ctgtttggcg aaaaaagata tacggtttca cttattactg ataggaatga tcttatgtgt
     3781 tttaaaatcc catttgtata aatcggttat aacgagtttt tcttcaccac ttgtattgtc
     3841 gagcacactc gcccacaact ttagaccgcc ataggaaaag tctagagtgt gcttgtcagg
     3901 taatttcttt gtaattagtt tatccacttc aactaagcta ccttgctggt atttcagtga
     3961 tgacacctga atgtattcca gatcgacact tccatctgaa tttgttttat ctatcgagta
     4021 ataaacaagg agatagaggt tgccgttttt atctttgtca ctatccagta caccgaaata
     4081 aacgtttcca ctgtttgggc cgtattgcat tgcatcgatc ttaatcactt ttccattctt
     4141 tttccctaaa aaagcatacg tggtatctgc agccttttgg tgacgctgta gcaggtataa
     4201 atcatcctca atatgtccaa aggtgtctat aaaaccagag tccatatcta agccgaatac
     4261 ttgatattct ttcggaataa taactggaga tgatgggtag tgaacaggac tatcattttg
     4321 aggcgatgca tatgcagtac tggtaatcga caatagtacg gctaacaaag aaactactat
     4381 tttttgcaaa ataaaacctc ctgtttaaaa tgatggaaat attttaggaa actgatgtaa
     4441 cctgcacaag catgactcta gggtattgaa ttcaagagaa gcacagaaaa cattttggtt
     4501 acatcataca ccagccgttt tacaaaacat tacttgtgag aaggggaaag atggaatgaa
     4561 gcgtagcaga catattttcc tagtcaattt gcaagcgaaa agataaaact cctgcaagga
     4621 gacaggagtc gaaatgtttg ctcgatatat cgagacttct gacgagaccg aagcaattgc
     4681 acaactgcgg gtcttttatg gcgacttagt tattaaccaa gttaatactc ttctataagc
     4741 gttagttggg ttatagatat gcagaaacca tctatctgtt gcaggtgggt aattttgaag
     4801 cacagataca ggttcaattt gatcaatgag ccatccagca ctgataaccc tcctattgcc
     4861 tgatggtatt aagttaatat acacatatga atagggttca agccttacgg gctgaaaacg
     4921 gtggagccaa aagccatttc cgagatccag tgttatacgt acatttttcc gacttagggt
     4981 gatgattttt ttccgtgtta cacctcttct tttcacactc ttgggtgatg atttcttttt
     5041 catgttttca ccttctacgg ttatttaagt ttcgtaggat cagcatatga aggtaaagtg
     5101 ataaacttgg actcatttac aagagttaaa aaaatggggt aattcaataa tttgagctca
     5161 gaccaatgga caccggcaat agagttggat atctgagcac aacgattcag gtcattcctg
     5221 aaacggttgg gtagtcaact ggtctttctg aaaaggacgg taaggataat ttacgagtgt
     5281 gatattgtat ccaactctta ccgcggtaca ggaaaagttg cacgatgcaa aacaggtgca
     5341 tatgtcgcaa ttggtgggac aacttcaaat catcggcacc atctatgaag acccggaact
     5401 gctggagact acttaacaaa agagaaattg tgaatatact tttatttaca attagagaag
     5461 tgaaatggga ggggaaaaaa gtgagagatg aaagggtatt ccgcattacg atagatgttt
     5521 caaatgtgaa aagtaacgag gatttacatt ctttgctaaa gagctcttta aattttccgg
     5581 atttttatgt tatgaatatg tctgcatttt gggatgccat tactgggtta gtagaaatgc
     5641 caataaatct tactttcata ggatgggatt cattaaagga actactccct gatgtaactg
     5701 cgacttttga gaaaaccctt gaacagtata acgattatta cccaaatcat gcttgcaatg
     5761 ttatatatag ttgaatcgta ttaacacaat atttcgtgtg ataagaacgg agggaaaaca
     5821 gatgagagat ctacaattcc agattcaaca acattcactg tatagacatt acaaaggaaa
     5881 gctgtactac gtaatggggc tggctgaaca ctctgaaacc aatgaattga tggtagtgta
     5941 tcatgcgcta tatggtgata acgaaatgtg ggttaggccg ttagaaatgt tcctctcaga
     6001 ggttgaggaa agtaaggaga atccgacagg tcaaaaatat cgttttgaat tagttcagta
     6061 aactaacgat ctggtgaagg ggtgggaaca atgatgcctg ctggaatccg agatgatgga
     6121 aaacacaaaa tgtttgaaac cggagcaaaa cgagaccgag caccagggaa aggcaggtat
     6181 gatctactct cgcctgtagc aatacgcaga atagcacaga gaagtgatgc cagtgaatcg
     6241 ctgtttttac tattgaaggg tagcgaccaa accaagccgt tgttaacgaa tcgcgaaaga
     6301 gaagtgtttg aactcttggt ccaagataag acaaccaaag agattgccgg acaactcttc
     6361 atcagcgaaa agactgtgcg caatcacatt agtaatgtta tgcaaaaatt aggtgtcaaa
     6421 ggtcgatctc aggcagtagt cgaactcgtt cgacttggtg aactagagat ttgaacccag
     6481 tccacccagc ctcccttttc ttcccttggt cggaagggag ggttttttta tgttcatttg
     6541 cgtccgaata ctcgatgtaa atatcaaaca atatggaatt tcgggcaaag aaagaagcag
     6601 agaaggggat ggtggaaggt tataggatcg aacggaactc gaatctcttt ggttgtcggg
     6661 atgtattcgg taatggggga cgtttaccaa ttatcaaagc gattctactt atcaaaatac
     6721 tcaggatact tactttaaaa catccagaat gagggaggtt gaaccaacta taagtgttat
     6781 caataaaatt gcaccagcga tagttacagc tcgccatgac ttggcataaa gaacagcgca
     6841 gaaaaaaaca aattcaacaa tgagaataag tacccatgaa tcaaaattca taaaacacct
     6901 caataatgta tggcataaaa actaaccata tattaccacg gatggtcggg tctaacagta
     6961 attaacacaa tgctccatat gtttaatcgt catccaactc agcaatttca cgagagattc
     7021 tttcttccgt tcgcagtctg ttagcactaa tttctttcag tgaatcctca ctgataaaac
     7081 gtactgcctc aggtataaga tctctggagg ggaattcaat tatttcagct ctctctacaa
     7141 gtgcgtacca taccttagga attttgtttt ctatagcaaa acggtatatt gttttggcct
     7201 ctataagcgg tatttctaat ttgatatgaa ttcgtgcgat tgtttgattt ttaatagaaa
     7261 aattcaacca gtttgtatgt tgatacttat agtaggttga ttcgattatt gaggcagcag
     7321 catacacttt ttgtttatcc ataaataccc cctataagaa aaccaataaa gtgtggagta
     7381 gttagtctac atgatcagaa aaatttacac aatatgtatt taagagaatg gagggaaaag
     7441 gtagatgcag cacttataaa gaggcattgt taatcgcaat cgattgtaaa tagaatgcga
     7501 gcgacatcta ggcattctgc gaacggacga ttataaattt cgtcatcgaa atattcgatg
     7561 aaaatacttt ctacatgttt ggccaactct tcaggggtgc tgtagttaga ttgaagcagt
     7621 ttaataatct catttatttc aattcggtaa tgatcgtgtt cgggatctat accaactaat
     7681 ccaatcgggt cccatcgatc aataatgctt tttactttag cataaatcaa ttgtttcacc
     7741 tcgaaatttg gtcagtctaa gtatattacc acaaaaatac gcaggttaac ttattagtta
     7801 atgaaataag catctaggag gcaattagga ggcatttaga atgtttcata acatccacgt
     7861 gttttcaaaa aatgaggtat actttaaccc tgtaactaaa gaatatgcat cattgtttat
     7921 acacaattca aatcatgcaa tacgttggtc ttgaacggac tgctgtgtat tggggaacgg
     7981 ggaaccggga agtgctcatc aacacgcttg gttccgccgg attaggtgtc ctgtccgcaa
     8041 tatggttatt gatagagggg aagaagcggt aagtgacagg agtattggga gaaagcgcga
     8101 gctccacctt cccgaagagg tggagcacga tatttgttag ctgtgaacaa caaagggtga
     8161 cgcttgcaga ttatacaagc tggcatactt ttgttgtaat cggatcaatt cggagtgtgt
     8221 gccaaattca acgattctcc cctggtccaa gaccatgatt cgatcagcat actgagcaga
     8281 tgagtaacgg tgcgagataa agattcccat tcgctccttg gtcaacaggt taaatgcatc
     8341 aaatacttct ttttctgcca aagggtccag cgaagcactt ggctcgtcga gaatatagag
     8401 gtcagcattt cggaggaaag ctctcgcgat ggcaatgcgc tgccactgtc cacctgataa
     8461 ctgaagacca tctgcgaacc attttcccaa ctgggtatcc aatccttctt caagtccctc
     8521 tgccaagctg cgcatgcctg attgttcaag cgcgtgatat agcttgtcat catgttgaag
     8581 aagagcaaga ttgccgaagc cgacattatt gcgaacggac atctcatatt gcataaaatc
     8641 ctgaaagaca accccgattt ttgttcgaat gacatctaag tcaaacgctt tcaagtcagt
     8701 tccgtttatc agtatctgtc cctcatagtc cttgtacaac aatgtaagca atttgactaa
     8761 tgttgttttg ccggagccat tctctccgac aatcgccaac gactctcctt tttttatcgt
     8821 gaacgagaga ttttgaagaa cgagtcgttc tgtttccgga tacgtaaagg aaacgttgac
     8881 gaactcgatg ctttccaaaa caaacggttc gttttgtcgg ggagcggcag gtatagcgac
     8941 tttttgttgc ttgacaggat cagatgaatc cctgtccaaa aaaaggaaca attgttccac
     9001 gtacatgttg tgctgagaca atccaatcag agagtgcatc aatgactgag acgtactgtg
     9061 ggttaacgtg atcccttgaa gataactaac caaattccct aacaggatct ctttcagaaa
     9121 agcagctttt atggcaataa agctcataaa agcaatcatc gcaatcgtca aacactcgaa
     9181 gacgagagag gtcttcaaac gagatgtggc gatctttttg tcttcataaa aaaattgtgc
     9241 gatcatatcg cgaaaatgtt tgatgagata ggggccgagt ttatagattt gtacttcctt
     9301 gaaagcccga tcatgggtta ataaatagct gatgtaccag ccttttctct cccgttcagc
     9361 cctgttccaa tgaatataga actcttgttg acttaaccga aagtaggaat agaaggagat
     9421 aagcggaaac aagatcagga taaacaccac ccaccatttc caaaagaata gaaacagcga
     9481 ggtagatacc agagaaattc caccggataa gatactaagt accagcacga atatctgata
     9541 gggacgatag ctggtctcct gttgcgcacg tttgagctgg tcctgcactt ccgcattttc
     9601 aaaatcggct aatcccagcg tgcttgcttt gtccaacacc atttcacgga ggcgattggc
     9661 gagcagggat tgaaacagtc cttcgacata attctgaagg agtgtaacaa gctgtttcac
     9721 taaaataaag gagagaaaca aaaggaaact gatggcgatc gtatcccagt cttggcctac
     9781 tcctgtggaa acggcgttaa caagctcctg ggtaacatac agcataccaa cagggaacag
     9841 cccttggata atattcagaa tcacaatggt tataaaatag cctttttcta ctgtccagaa
     9901 aaggcggaaa attttcggcc agtttcggaa agactggatg acggtcttta ggctaaacac
     9961 gtcctctgtt gttgcgtaca tgtggtatcc cctaacttag ctatttcagc ataaacatac
    10021 agtcccattc gggttcatcc agactcaggc agcttaacaa gacaagcgcc acgcctgctg
    10081 ctccggtcaa caatcctgga tggtcttggg gttgtccgag ctcgatgtct tgaaatccat
    10141 aagcagtgtt ttcgttaaag ctgttcaaaa gctggtttat cagtgtttcg cggtaagctg
    10201 caagaacatc agagcccgtg ttcatcatca ttcgttggat catccaaagc gctcctgcat
    10261 aaccgtgaca aaacgtggga gagtcgaaac cgaacgattc tactgatcgc tggacaagag
    10321 agaggtagac tttttgcgcc aaagactgga tttgggtgtc gcccaatgct tcgccagcca
    10381 gccacaatac acgtgctatg cttggttccc cgtaacacca tgatgcattg tgagcaaaat
    10441 tgttccgcat ctgtccgcag atttgctctt caaagctgat tctctccggc caaattggtc
    10501 cgtactcgtc ttccgccttc cacttgtcgt aataggaaca aagcttgcga atggcctctc
    10561 gttgtccggc tacctctact cccgcaagca aagcaagaga gagcaaggca aacggaccgg
    10621 caataccgtg agaaatcccc agattaaagt tgccattagg gtattgtttt tgttcaattt
    10681 ccaaaaactg atcttcgctc ttgatatgcc agcctggaac aatcctgtca tctagttgga
    10741 tatcttccgt taattgaacc gtgtatgaca atgctttgat aaggtttttt ttacatgcgg
    10801 aatgttcttt aaaggagaga agatatcgac cgataccagc caatccatca atcacatcgt
    10861 aatcaggcat gaatacattg ttgccgattc gttctcgtgc ttggtcgatg aactcgtcaa
    10921 ttgcaggctg cataacaata tgcagttttt cgatgaagtt ttgatacctg ccccgatcac
    10981 gagcaagaat ggaggcgacc acaggtgctc cggataatcc agtccacagg gatagcgagt
    11041 gaaacgtatt cgcgttcatc ccggtttgta catggaccaa atagtgatgt gcgatgacat
    11101 cccattgctc atcagggtat tgtcgatcca attccgcata aaagagggcg atgcccaaag
    11161 caccggaggc aagcgaacct gtgccgggaa gaggttcgcc caagaccgca tgaggagatt
    11221 gaagcttacg ggctatctgc tttactacat actctatgtt tttgaccagc gtatcgtctt
    11281 taatcggttg ccagctcttc gtattagaaa gcatgcgcag tctcctttgt gcgactttcc
    11341 tcttgcagca ggaagtatcg caagttgtgc agggtatggc gagccaaggt cagcactttc
    11401 ttttcacgtt cgcgatctac tccaagcagc ctattgatat gcagatgaat gatgctgcca
    11461 atgatctgat cctgtgaatt atacagctcc gattgtgctt tcagtgaatg catgaccgta
    11521 gaaaagcttt gaatcgtctc tgatcttgtc tgcagtgcct gatagagaat agggccgtcc
    11581 tccaacgctt ttaattcctc ccaaccgttt gtatagcgtc ctgcctgtag atagaactcc
    11641 ctgtctgtgc ggaaatcatc gaggtacgct ttatactgaa tcaggctgtt caggaagcct
    11701 agcttttcgt cgatcgaatg caagaattga tgcaaaaggt cgataatgct gattacggca
    11761 accttctcca agggcagctt cagctgcttt gtacgatgca gatgtagcca atgggccaca
    11821 accatactgt caactgcaaa tatttcttcg gccagggaaa tcaattcagg cccgccatat
    11881 cgttcaattt cagggtcata tgtatcaatc gttgctttgg agaggtatcc ctgtttttgc
    11941 atgtctgaca tccatcgata catttcagag aaaatagatt gcagtccttc ggtggatgct
    12001 gcttgaaaac gcagacggat atgcggtttc ggatcggcgt acctcatgaa gaagaccttt
    12061 tggcaagcac cttgcgtgcg catcgcttcg catagagact tgagtggaaa ggcaatgaac
    12121 tcatccactc tggtttcatc gcagtaaagc ttgtagaata gccaatcact tcctggcatt
    12181 ttgaatcgtt ctaggtccga aataagcacg cgattcgatt ggactccatt ttccacagaa
    12241 acggaatcga tggcagtcgc ttcttccgga gtatttttga caagcgggaa gacacattcc
    12301 atatgaaagg cgccgtcttt cccatgaaca acacagtcct tcagctcagc tcctacttca
    12361 gttagaacaa gggtctcacc agaattccgc ttttgaagct cccgaatcaa ctcggcgaga
    12421 tgtctttgat ttttcagatc gagcaacatt ttattgtcat attcggtgat atacacgtaa
    12481 tctggaacgt tgtaatggcg tatccagttt tgcacggctt ccatccagcg ttcttttcca
    12541 tcttttttgg atacagatag cagctcctga tccacattcc acgtagctgg tgccagtatg
    12601 atctttccgt aacgcagccg aggcagaacg ggagcatgac gaaagctgcc ccaactgaat
    12661 ggtacccaat ttcgctgctt taccatcccc aactcgcaca gaaaacgata gacgtttgga
    12721 acagagcctg tgtagttaag catatggcct gtaacaggaa tgatttcctt attcatcgat
    12781 cgtgatttca aatagaagga atgcgatgta gcccctacaa ccaaatcaga taggggaata
    12841 cttgtcgagt gatgctcgcg ggaaggggcg ccaatcaaaa tctcgtattc ccgcttgctt
    12901 ttcgaaagaa cgacattggc agcccttccg tgtcgtggaa agtaaacaac ttcagcaact
    12961 atactgtccg gatacgcctt ctggtgttcc tggttgatct gctcaagatt ttgttcgaaa
    13021 gactctccca gcatgtcagc gaagcgtcca aatgattttc cggctaacgc tgatcctgta
    13081 ttcgccccaa catgaacggt gtaatccccg ttgtccatgg cctgtggcga agcggcaaac
    13141 aaggaaacat acaattccat cgagggcggg acatgttccc atttgggtga taccggctcc
    13201 agcttcttga tcaactcgtc cgtcagatct atttccgtgc ttcctgtcaa aagcgagtgg
    13261 gataacaact gtaagagaac cttctcattt attttgtcgg ggctagtcgc gttatcagat
    13321 cttttgctaa ttggattttg gtaggtggca ggagcgccta acccccggtt ttcatccagc
    13381 aattccagca agggaacctc tctctcaaat ccgtatcgtt caataaaagc gtcccgatac
    13441 tccgccaagt gagacagtcc aacgtgattg ggtgataatc tccacagcag ttctgctgct
    13501 ttgctcaggt ccttggcaat cgaatttggc agcgttacct gctccgttga taacgataaa
    13561 tctacttgta acagcgaggg tgaagattct accgatttca ttttggagag catggagagg
    13621 aaatgcgttt ctccctggcc aatctccagc tgatcatagg cgatgatgtc ctgcctaatt
    13681 tccagcaggt gccggtacaa ttcatctata cctgttacgc gctccaatac agcaagcagc
    13741 tgatcaaacg gcgatgaatc agtgagacgc ggacgaaggc ttgtaaacag aaactcattt
    13801 tgaaccaatt gaaacaaaaa ggattcgatt ctgctgtctt ccgtatccgg atatgattgt
    13861 ttgatggtct gcaataattc cataaacggg atcggcactg ctgccttatg ggaaacaagc
    13921 gtgatcaaat cgtttagcgg aatcgaggca ttttccattt cgtagccatt gtgcttttga
    13981 ccgtaccgcg taatatacgg cagggaaacc cgattgccca ctacctcgta cattgtgttt
    14041 gtctggatgt gaagctgctt gaccacatcc agatttcctt ccagagattg aacgattttc
    14101 aggagccatt ccatgtcagg gcggctccgt ttttttatgc tgttcgattt tgtttacgat
    14161 gagttgggta tgtgtatcaa aatgcccgca tgcgatcccg gaaaaaagtc caaacggcgt
    14221 cgctcgcgta ctcattcgga ttccatatcg taaacagctc ctcgcagcct gctcaagctg
    14281 ctcacggtca gcctgatcca gtttgtttag cgattcaagc aacgaaggac tggcaacggc
    14341 aatgcactct cgaatgatgg cttgttttct cggatcgagc ttgtcaagtc gccaatcgga
    14401 ttgacataac tccaaaaaca tatgtatagg cagcaatggc gttcgaagca tgaaaaaatc
    14461 catcgtgcga aaaaaggatc gggattcttt ctttgcgtgg tttttcacat gtaatggacg
    14521 ttccaattaa gatccctcct tttgtaaatg gggaaaggat agtaagcgct ggtgaaagaa
    14581 acgtcttgca ccatacattc actatccaaa tagcagggtc agaccgaccc aagaaggttt
    14641 gtgctccaca ttggttttag tgagttgctt tcctattttt catccgagaa tcctttgcat
    14701 gaccacgtgc aattgcagca agttattttg gtcatcaaag tgtctggata tggccaagag
    14761 tctggtttaa caccagaagc acttacggtg tttacttgta cgtccaaatc aaacatgtcg
    14821 tttttcatag tcagttcctc caatttttgg cagtttcaag aagtaaaaga gctgccgatg
    14881 ttagtgagtt gttaccttat ctctcatccg ggcctttaca ataacctggt gcaattatat
    14941 ctcgtgtagc aataataaga tctcgtggga tagcaacaaa tggtatgagg gtcacaataa
    15001 gtgtccggtt taacaccaga agcacttacg gtgtttactt gtacatccaa atcaaacatg
    15061 tcgtttttca tagtcggttc ctcctatttt ctaatctttt tttgagtgaa agagctgcca
    15121 atgtggagca cgagaattga tggaataaaa ggaaaataac accaattatt ccaaaagaat
    15181 taaagcatat acaattgtta aaattcaatc tgttgttttc tacaaatttc tacatatcaa
    15241 aaatatttca tctaattaac tatcaattgt taaatatgtc agggaacgtt gatcagaggg
    15301 caaggcaaca tctcttgatg ggatcatggt aaggttttta tggggcggcc atctggagac
    15361 tggcttggtt gaaagagcga caggagcgtt ggagatggag aagaattgtg ggtggaaata
    15421 atcaaaaaat gtcgaatgtt gaatgaaaat attgatgtct ttgcagtaca gcggtatttg
    15481 gaaaagctaa ttcaacgcag ccaatgaggc tgcgtttcta agtctctatt cacgaacaaa
    15541 tagctgaaaa acgtctcctg ctcatagccc cgcggctcct cttcttccca cagcagttca
    15601 tcttcctcat cgttcttggg ccatcagtac ttttcgtcca gcagctcgtt cattgtctca
    15661 accgtatttt gtgaatccat gtagtcgacg gttatggcag aagctacagc caagtacaac
    15721 gtaatttcct ccgaagagac cttctctggt ttttgtttgg caagctctcg caggagtata
    15781 agcaggaccc aaggcgtcgt ctgccacaag gtgccttggt gctcgatcag gttggccagt
    15841 tccccatatt gccccgtctc tatgagccgc tcaaggcaga tggcattgat ctgaacaatt
    15901 atccgaaagc tctcgttgat ctctacacct acgatggaca aaactacgcg ctaccgaaag
    15961 atttcgacac cattggcctt tggtacaaca agaagctgtt tgacgacgca aaagtgccgt
    16021 atccagacga aacgtgggat tggaacaagc tgaaggaagt agcaaagcag ctgacggatg
    16081 agaaaaaagg cgtttgggga attgcagcac ctccttatgg acaggacggc ttctataaca
    16141 cgatctttca aaacggtggc tatatcattt cggaagacaa gaaaacgtcc ggctatgaca
    16201 aaccggaaac gatcgaaggc ctcaagtttt ggaccgacct gatcaacgaa aaagcatcac
    16261 caacagcagc gcaattgtcc gaaacagagg caacacagct gtttgaatca ggcaagatcg
    16321 cgatgatgta caacggatca tggatggcat ccgcttttca taaaaatgag tatacaaagg
    16381 acaaagtgga cgtgacgtat cttccaaaag ggaaagagaa cacgagcgtc attcacggcc
    16441 tgggcaacgt gatttcggct aataccaaac atccgaagga agcatgggaa ttcgtaaaat
    16501 tcttgggctc gaaagaaggg gcagaaatcc tggcaaaatc gggtgctgcg attccggcat
    16561 ttaacggaac acagaatact ttggtacaat ccatgccgaa ctttaatctg aaaattttta
    16621 ttgatcaggc agctgtagcg aaaccgtatc cgatctcgaa ggacacggca aaatgggcca
    16681 agctggaaac agagctcatg accaaggcat gggctggaca aatgagcgta gaggatgctt
    16741 ccaaagagct cgcgcaaaaa atgaacgaaa tgcttagcca agaataaaag gtccatgatg
    16801 gatggcttcg catcatggac gaggccatcc ttttttgaaa agctgatgta aggagggaat
    16861 gaatgcgatg agcagccagt tgcagcctga aatgcacgcc gccgtccagc caaaaacgaa
    16921 aaaatcgttg aatcgcatga agagaagtga ttggttctgg gcgtatctca tgattgctcc
    16981 cacactgatc gggttgggtg tcttctactt atggccaatc gtacaaacca tttatttaag
    17041 ctttaccaaa tggggaggat tcggcaagta caagtgggct ggcttacata attacgagtt
    17101 gttgttcaag gacccttact tgtggatcgc gctgaaaaac acgctgattt atacagtaat
    17161 cgcagttcca gtaggtatcg ctatctccat ttttatcgct gtgctgctta atcggaaaat
    17221 taaggggatt gcgatttatc gcaccctgta cttcctgccc gttgtgacga tcgcagcagc
    17281 ggtggcgatg gtgtggagat ggttgtacaa cgctgattac ggtctgatca attatttgct
    17341 gggcttgata ggcattgagg ggccacgctg gatttctgat cccgccattg ctttgtatgc
    17401 ggtgattatc gttgccgttt ggagctccat cggatacaac atggtgattt ttctggccgg
    17461 actgcaaggc atcccgagaa gctattacga agcagcagaa attgacggcg cgggaccggt
    17521 tcgcatgttt ttcaaaatta cgttgccact gttgactcct tcgatctttt tcgtcagtat
    17581 cacttccttg attggggctt ttcaagtatt tgacctgatt tatctgatgc tcggaagcaa
    17641 aatgggcaat ccggcgactg agcaaacgca gacgatggcg tacttgttct ttaccaatgg
    17701 atttgaatcc gggaacggtg gctatgcggc cgcagttgcc gtcgtgcttc tggtgatgat
    17761 cctgatcgtc actgctattc aaatgaaatt gcagaaaaaa tgggttcact atgattaaac
    17821 aaagctgaac agacgggagg gatatggaat gagtgtctat acgagtcgga acaagatagg
    17881 caagaagtta ttgattcatc tgctgttgat tgcaggtgct ctcgtgatga ttgcaccatt
    17941 cgtctggatg gttctcactt cgctcaagtc actgggcgaa tcgacacagg tacctccggt
    18001 cattttgccg accaagtacc aatgggagaa ttacactcat atttttgaga tgctgccctt
    18061 cttggacttt tattggaata ccgtgatcac aacagtagcc aaggtaatcg gacaagtatt
    18121 cctctgctcg ctcgcggcgt acgcattcgc gcggattgaa tttccagggc gaaacgcctt
    18181 attcatcctg ttcttgaccg ttttgatggt gccaggtcag gtgtttctgc tcccgcaatt
    18241 tatgatcatg aaggagcttg gctggctgaa caccttgaca gcattgattg taccgggatt
    18301 gttcagtgca ttcggtacgt ttcttctgcg tcagtttttc atgtcgctgc caaaagaact
    18361 ggaagaagcg gcgaagctcg atggctgcaa ccattttcag atttattgga gaattatgct
    18421 gccgctggcg aagcccggct tgatcgcact cgccattttc gtagcgctgt ggtcttggaa
    18481 cgacctgatg tggccgttga tcgtcaacag cacgcctgat aaaatgccgc tctccgctgg
    18541 tttggcgtac ttgacgggtg agcacaccaa tttgacgaac tacccgattt tgatggcggg
    18601 ctccgttctt gccatttggc cgatgatcat cgtctttatt ttcttgcaga agcattttgt
    18661 cgaaggaatt accctaactg ggtccaaata gactttttcc caaaaggagt gaaaccatta
    18721 tgcatcatgt tctggtaatc ggagcaggaa ccatggggac tgttcacgcg aaatcgtatg
    18781 ctgccatgga aaatgtcaag ctggtcggga tcgtcgatat ccgcagcgag agaggaaaag
    18841 agctggcagc cgagacaaaa acggaatggt ttgagaacta tgaagaggca ctggaaaaac
    18901 tggcgcaggt cgacatcgta gacgtgtgtt tgcctacgta tctccataaa acctatgtga
    18961 aaaaggctgc ggatgcaggc aagcatgtca tttgcgaaaa gccgttggct cgtgataagg
    19021 aagaagctcg ttttatcgtt gattattgcc gggagaaaaa cgtcaagctg ttcgtcggac
    19081 acgtcctgcg cttcttcccg gaatatgaaa agtcccgtca gctggttaat gacggcgcga
    19141 ttggtaacgt tggtgtggca cgtacgttcc gtggtggtat cttcccgaca gcgtggaatg
    19201 actggtacgc cgactacaaa aacagtggca gccttgtttt agatatgatc attcacgatt
    19261 ttgacttttt gcgctggtgc ttcggggatg tggagcgtgt gtacgcgaaa ggcttgcttg
    19321 gtcgaggttt tgcccggatg gattacgcac tggttacgct tcgcttcaag aacggcatga
    19381 ttgcacatgt ggaaggctcg tgggcacatg aaggcttcgc gatgaaaatg gagctggcag
    19441 gcaaggaagg catcatttcc tacgacagct cgaaagaaaa accgcttgtg gcagttaatc
    19501 gctcgaagca agcaggcatg agcggagtcg cagttccgga gagtccgttg cgtgaaaacc
    19561 cgtatttcag agaactgaag catttcatcg agtgcatcga ccgtgatctg gagccactcg
    19621 tgacggcaga agacgccgtg aaagcggtag aaatcgctcg tgctgcgctt gtgtcaatcg
    19681 aaacgggcaa acccgtaact ttggtgtagg aggggactgg acatgaaact cggaatcatc
    19741 agtgttgcac atatgcatgc atacagctac gcaaatgcgg ttgcgaaatt agatggggtt
    19801 caattggtcg gggtagcaga tgaggatgaa gtgcgcggaa aggcggcggc agaaaagttt
    19861 ggcgttccgt tcttcgccga ttatcatgag ctgctcgcaa cggatatcga tgcggtcatc
    19921 gtcacctcgg aaaacgccaa gcaccaagag catacgttag cggcagcgaa ggctggcaag
    19981 cacatcttgt gcgaaaaacc gctggcgacg acagccgagg ctgctcaaga gatgatcgac
    20041 ttttgccgtg aacagggcgt cattttgcag acagcattcc cagtgcgatt ccatccggct
    20101 gtcgttcgag caaagcaatt ggtggagcaa ggcaaggtcg gacgtatcat ggcgatccgg
    20161 ggtacgaacc gtggacaaaa tcctggtggt tggttcgtcg atccggaaaa atccggcgga
    20221 ggtgcagtga tcgatcacac agttcacgtc gttgatttga tgcgctggtt tatgaactct
    20281 gaagtgcgtg aggtttacgc ggaggtagac agcaagtttt ccgatacgcc gattgatgat
    20341 tgcggcattt tgacgatgga atttgaaaat ggggtatttg ccacactcga ttgcagctgg
    20401 tctcgcaaca aggcgttccc aacttggggg gatgtgacaa tggaaattat cgggacagaa
    20461 ggcacgatct cgctcgatgc tttttctcaa aagctggatg tctattccaa tgaaaaaggc
    20521 ttgaagtggg tcaactgggg agatgacatg gacagtcaat tggtcaaaga tttcgtcacc
    20581 agcgtgcgtg aaaggaaagc gccgtcgatt acgggtgaag acggcttgcg agctgtggaa
    20641 gtagcactcg ccgcttatca atccgctgaa cagaagcaac cagtcgtatt acgctaggac
    20701 ggtgaaggac gcatgagtgt acgtgtaggc atgatcggcg taggtggaat cgggcagcat
    20761 catctgaaag gcttgttggc ggacgaaagg gtaaaggtcg ttgcagtgtg cgacgtgaac
    20821 caagaggcgg ctgcagagac tgctgagcgc attggtgcgc atggctacac ctcttggcgt
    20881 gagctagtag aggcagaaaa gctggatgct ttgtttgtgt gcgtcccacc ttttgcacat
    20941 gaagagattg aggaaacagc ggcggcgaaa gggattcatc tgtttgtgga aaagccaatt
    21001 gggctggaca tacagaaagt gagcgaaaag caagaagcga ttgaaaaagc aggtattatc
    21061 accgcgactg gctattgcct gcgctatctc gatatcgtgc agaagcgaaa gcgtacttgg
    21121 agggcaagtc gattgcactc gtccgcggtc attatttgac caagttcgtc acgacatctt
    21181 ggtggaggga aatgggcaag tcaggtggac agcttgtcga gcaggcgacg catacgctgg
    21241 acatgatgcg gtatttggcc ggagatatcg agaaggtcta tgcgcagatg gccttgctgg
    21301 tctcgcgtga cattccaaac atcgatattc cagacgtgac ttctatcagt atggtatttc
    21361 agtcaggggc gctaggacat ttggatacgt gcttcatcca accggatcac cgtacaaatg
    21421 tagaaatttt aggcaaagat ttccgtgtca tgattgacgg aaagcaatta gcgatcatgg
    21481 atgagcaagg aacacgtacg aaagagagca cggcggatat gtacgtggag caagatcggg
    21541 cgtttatcac agcgattgtg acaggggatc gcagcttgat tctgtcgccg tatgaatcag
    21601 cgagaaagac gctagaagta acgttggcag cgaatcaatc ggcacaagaa ggaaagccgg
    21661 ttagaatttc gggaaaaggg gagtgaggcg catggctttt caaaaaggaa tcaatgcttg
    21721 gtgcttccca aaggaaacga gcgtgcaaga aatgtttcgc caggcggaag cacatggcta
    21781 tcaaggggta gaactgaatt tggacgaagg agatactccc tttcacctcg agatgacaga
    21841 gcaggaatta aaggggctgg cagacgaggc tcgcgagctc ggtttggagc tgccaagcgt
    21901 ctctactgcc cttttatgga aatatccgtt gacacataat gaggaagcga tccgagagca
    21961 aggcatccgt gttgtcgaga aaatgataga ggcggcaagc atttttggct cacggacggt
    22021 tctcgtcgtc ccaggtctcg taacagccga ggtgtcgtat gatacggcct acgagcgggc
    22081 gcgtgaagca ttgcagcgct tggcgaaaaa ggcggagcag catcaggtat acatcggggt
    22141 agaaaacgta tggaacaaat ttttgctcag tccgctggag atggcccgct tgatcgatga
    22201 agtagacagt ccttgggtag gcgcttattt tgatgtaggc aatgtgctgc aattcggttt
    22261 tcctgagcaa tggattcgca ttttgggcaa gagaattcag gctattcacg tcaaagattt
    22321 caagacaacg acaggtaata tcacaggttt cgttccgttg ctcgctggcg atattccatg
    22381 gaaccgtgtc gtggaagcgt tgcgtgagat cgggtatgac ggctacatca tcccggaaat
    22441 ctcgccttac agccagttgc ctgagcaatt gatcgcgcat acgtcccaag cgttggacgc
    22501 catttttcaa tcgtgaatgg acaacaagga tgtgaagcgg aagatgaatc aagacaaacc
    22561 atatgccatc gggattgatc tgggaggcac gaagatcatg gccgcgatcg tcgaccagca
    22621 tggcaagatc ctcagtcagg cgaacgcagc gacccaaaca gaagaggcag ctcaggtagt
    22681 catttgccgt atcggtgatt tggtgcagac tgtcctagac gagagcggca tcaatctctc
    22741 acgtattcgc gggatcggga ttgcaactgc gggaataatt gatacacagc gcgaaatggt
    22801 catttttgcg agcaatttaa actggagcga tgtaccaatc ggcgcgatgc ttcaggagcg
    22861 gtttggtgtc gccgtacaat tgatcaatga tgccaatgca gcagcggtag cagaatgggc
    22921 gtttggaagt gcgcgaggca cgaaagactt gatctatgta acggtcagta cgggtgttgg
    22981 tgctggcatt attagtggag gacggctgat tacaggcgtt ggagatagtg ccggggagtt
    23041 cgggcatatt tcgcttgatc ccgaaggacc gctgtgcgcg tgcgggaata gaggatgcct
    23101 ggaaaattac tcgtctgggc tggctttggc aagtagagcc agggagcagc ttctacaggg
    23161 tgttacaagc tcgttgcttg ttgaaaatgg gaatgacctg agcaggataa cggctagaga
    23221 ggtcggagag gcagcggtac gaggagactt gctcagcatg accttgatga aggaagctgg
    23281 ttattatctc ggggtcggac tgaccaacct gatccatctg ttcaatccgc aggtgatcgt
    23341 cattggtggc ggtgtgatga agaacggaca gctgctgctt gcggaagcga agaacgtcat
    23401 tcgcgagcgc tctatctctc ggatggcaaa ccaagcgagc atccagttga cgacaattgg
    23461 agcggaagca ggtgtgctcg gtgcagcagg catgtattat ccgtccgagc gtgaagtggt
    23521 tgaggtataa cggaatgaaa gtacgagaag ccgatgtttg gtagacatcg gctttttcct
    23581 gttccctgta cagtgcaagt cataggaacc tagacctaaa ttctatctat tggtaaaata
    23641 ttgattggaa aaatcttcac ataacatgaa agagagacag acggaggggt accatggcag
    23701 atgccaaaac agcaaaagca gcgaagaagc ccggattttt caaagaactc cttacttttt
    23761 tattggtagt tgccatcatc ctcggaattg ctagcggtgc aattttctat ttatctggga
    23821 aaaaccttga tgatctacta ggatcgcgac ccgtagcaaa aaaggaaacg aatcagcctg
    23881 cacccgtaag tccggtgtct actggtcagg aagcgggcac aaatcagaag gcaaacgcag
    23941 tacctgtttc ctctgaggaa aatgatgcaa cagaagaggc gatgccagtg ggttaccctg
    24001 tcgatacgca aggacaacaa agtaatgctg taggacaagt ggcacaacca gcacttccta
    24061 cccaaaaggg atctctcaaa ggtacgatta cgtggcagta taacgatttt gttgggacaa
    24121 agccagacgt gaatgctaag atttttctaa taaggaagga ttttaatata aatacaatta
    24181 ccgatatgga agagaaattg tttatttcga ttgaagctgc tcctaaaggg tcgggattgt
    24241 atactgcaaa agcaaatgga tatgggaatt acgagattgg gaatgtacct gttggagaat
    24301 attacatcat cgttgtctcg ggaaaaactc accgtgacat tcgccagcca gtagatgaat
    24361 attttacaag tatattcacg ccttacgtga ggaattggga ggactttaca ttgttaagtc
    24421 tgggaacgaa taaatatgag ttctcaccca ttacaatcga agaaaatcaa acactcgatt
    24481 tcagtcacga ttttggttat acgttctatt aatcttgttt tggcct
//
