LOCUS       NZ_CP022161            21524 bp    DNA     linear   CON 15-DEC-2024
DEFINITION  Streptomyces capitiformicae strain 1H-SSA4 chromosome.
ACCESSION   NZ_CP022161
VERSION     NZ_CP022161.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces capitiformicae
  ORGANISM  Streptomyces capitiformicae
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10989391)
  AUTHORS   Liu,C.
  TITLE     Streptomyces capitiformicae sp. nov., a novel actinomycete producing
            naphthoquinone compounds isolated from the head of Camponotus
            japonicus Mayr
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10989391)
  AUTHORS   Liu,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2017) Life of Science, Northeast Agricultural
            University, No. 59 Mucai Street, Harbin 150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. Feb-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002214185.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 14:26:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,013
            CDSs (total)                      :: 9,935
            Genes (coding)                    :: 9,274
            CDSs (with protein)               :: 9,274
            Genes (RNA)                       :: 78
            rRNAs                             :: 2 (5S)
            complete rRNAs                    :: 2 (5S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 661
            CDSs (without protein)            :: 661
            Pseudo Genes (ambiguous residues) :: 0 of 661
            Pseudo Genes (frameshifted)       :: 220 of 661
            Pseudo Genes (incomplete)         :: 571 of 661
            Pseudo Genes (internal stop)      :: 32 of 661
            Pseudo Genes (multiple problems)  :: 155 of 661
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:06:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9807551
            Orig. end                         :: 9829075
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022161.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21524
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="44"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21524
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21524
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11524](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11524
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            494..1261
                     /locus_tag="CES90_RS44075"
     CDS             494..1261
                     /NRPS_PKS="Domain: ECH (4-246). E-value: 4.2e-75. Score:
                     244.2. Matches aSDomain:
                     nrpspksdomains_CES90_RS44075_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675101.1"
                     /locus_tag="CES90_RS44075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_189788289.1"
                     /transl_table=11
                     /translation="MSVHLEVAEGVGTIRLDRPPMNALDIATQDRLGELAAEVTERDDV
                     RAVILYGGEKVFAAGADIKEMELVDHAGMVRRSRPLQDAFTAVARIPKPVVAAITGYAL
                     GGGCELALCTDYRIAADNAKLGQPEILLGLIPGAGGTQRLSRLVGPSKAKDLVFTGRMV
                     KADEALRIGLVDLVVPAAEVYEQARAWASRLAKGPALALRAAKESIDQGLETDLDTGLT
                     IERNWFAGLFATEDRERGMRSFVEEGPGRATFL"
     aSDomain        506..1231
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CES90_RS44075_ECH.1"
                     /evalue="4.20E-75"
                     /label="CES90_RS44075_ECH.1"
                     /locus_tag="CES90_RS44075"
                     /protein_end="246"
                     /protein_start="4"
                     /score="244.2"
                     /tool="antismash"
                     /translation="LEVAEGVGTIRLDRPPMNALDIATQDRLGELAAEVTERDDVRAVI
                     LYGGEKVFAAGADIKEMELVDHAGMVRRSRPLQDAFTAVARIPKPVVAAITGYALGGGC
                     ELALCTDYRIAADNAKLGQPEILLGLIPGAGGTQRLSRLVGPSKAKDLVFTGRMVKADE
                     ALRIGLVDLVVPAAEVYEQARAWASRLAKGPALALRAAKESIDQGLETDLDTGLTIERN
                     WFAGLFATEDRERGMRSFVE"
     misc_feature    complement(1378..1393)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.55"
                     /tool="antismash"
     gene            1406..1828
                     /locus_tag="CES90_RS44080"
     CDS             1406..1828
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891497.1"
                     /locus_tag="CES90_RS44080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_189788290.1"
                     /transl_table=11
                     /translation="MDHGEDEILAEELAALGAVVGGSRRLTRLVAKLMRKNVHEIDLEM
                     PLPFDDAVRRVAKVLGHAGRAVGSMHVEPGVDQETIRVVTSGGAGGMNPVVVTALVTKG
                     GMGSSKVRLRAAAKEGLIKQRAGEKTAARLAGWLSE"
     gene            complement(2186..2929)
                     /locus_tag="CES90_RS44085"
     CDS             complement(2186..2929)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CES90_RS44085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_189788291.1"
                     /transl_table=11
                     /translation="MPLAALRQGVEHVVGDDLRPTTVLALGGRGVAPLQGRHPDVLLLG
                     LRRRREEREQQLLGPGEHLQDQAVGGEVVGERGEFGGVTAEPLHLRRSSVHDPLPRLVG
                     IAWSADVSASTPDPVLGAVSERPADIPLEVRSLLSDPGLLLTTEPTRVIELLGRMADPW
                     SRAVAAVYRTSAEVTRRWHRFSDGRYWRWMRHGWVMRSWPHGSGAQMCRDSPIRSRVWS
                     VIRPGRAALLPTLGSCVLSPATVVL"
     gene            complement(2985..3341)
                     /locus_tag="CES90_RS44090"
     CDS             complement(2985..3341)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012434.5"
                     /locus_tag="CES90_RS44090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_308437942.1"
                     /transl_table=11
                     /translation="MRGVTSVTREHVDRLTANGLEVIASGANVPFADPEIFYGPVYEHA
                     DHSVAVVPDFIANCGMARTFALLMQGNLEISDESIFEDISSTIESALKHCHARSQAPTR
                     VASTAFAIALDQLL"
     gene            complement(3296..3418)
                     /locus_tag="CES90_RS51490"
     CDS             complement(3296..3418)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CES90_RS51490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_268257081.1"
                     /transl_table=11
                     /translation="MRADDLVPFDQVNDTIWDTGAEVFFPCAASRLSHANTSTV"
     misc_feature    3519..3533
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            3594..4193
                     /locus_tag="CES90_RS44095"
     CDS             3594..4193
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018548238.1"
                     /locus_tag="CES90_RS44095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_189788292.1"
                     /transl_table=11
                     /translation="MPDIKHFDPDAALETVCRLFWRQGVASTGIQDVVTATGLNRSSLY
                     ATFGGKQELYLAALRRYMEQRSQPMFRRLAQDERGLPAVSEFFAGLIEARCSGEYARWG
                     CMVSDAHAGAENSDPEVRAVLDQHHRELRDALHAALVTADAQGQLAPGCDPGACADLLA
                     LLAYGVNLRSRAGADARDLNRTVTTALASLGARATP"
     gene            complement(4219..4479)
                     /locus_tag="CES90_RS44100"
     CDS             complement(4219..4479)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CES90_RS44100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_229914482.1"
                     /transl_table=11
                     /translation="MRRCPRPSSPERVDFRLVRGPVPAVTESFELGEQGSRTRLEYTGE
                     LSTDLWRLGQWWGGLVAPRWEATVAGSLAAVKEEAERRARR"
     gene            4484..4870
                     /locus_tag="CES90_RS44105"
     CDS             4484..4870
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024770.5"
                     /locus_tag="CES90_RS44105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_268257082.1"
                     /transl_table=11
                     /translation="MISGPDHPFCLARLFGHSSALAEAGLPLEPGPVVKTQLTREHGYT
                     AARELLSRSDRPTAVFTANDMQALGVYQAARELGLRIPHDLSVEGFDDVPAVAWMDPAP
                     DHGPSAVGRDGGSCHRADPGARPG"
     gene            4824..4949
                     /locus_tag="CES90_RS51495"
     CDS             4824..4949
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024770.5"
                     /locus_tag="CES90_RS51495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_268257083.1"
                     /transl_table=11
                     /translation="MAAAATELTLALGRGEQVPQVGLEIATTLTVRESTAPPKAA"
     gene            complement(5314..6081)
                     /locus_tag="CES90_RS44110"
     CDS             complement(5314..6081)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1260: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020557458.1"
                     /locus_tag="CES90_RS44110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_229914516.1"
                     /transl_table=11
                     /translation="MTCQDDHARWSEAEVREDYRLVLVCRGRFRRRVAGAAADIDSTMA
                     YVGVPGEEEHFAHPAGGDDCTSISLTPALWHVMAGDVARLATQNVYVDARLDLTHRRLL
                     ATARTGDVDYTLTEELLGLLATTVRQVVSGPTPLSAQAQGNQAALVAAARQAITEGHPA
                     SNGLLPLAEVLGVSPYRLSRSFSRELGVSVTQYRNRVRIGRALDRLEEGENSLGALAAD
                     LGFADQAHMSRTIRQYLGRTPTALRRLLAPRTP"
     misc_feature    6071..6081
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    6168..6183
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.23"
                     /tool="antismash"
     gene            6321..6683
                     /locus_tag="CES90_RS44115"
     CDS             6321..6683
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020548301.1"
                     /locus_tag="CES90_RS44115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_189788468.1"
                     /transl_table=11
                     /translation="MPALAEFTAVVIDCADPAMLAEFYRKATGWEITYSDQDFASLGNG
                     GRMQIAFVRIEGYQAPGWPDARKHAHLDFTVTDLESTAKELLALGAAKPEFQTGEGKWV
                     VLTDPEGHPFCLTTGD"
     misc_feature    complement(6354..6368)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.84"
                     /tool="antismash"
     gene            6626..7126
                     /locus_tag="CES90_RS44120"
     CDS             6626..7126
                     /NRPS_PKS="Domain: Polyketide_cyc2 (30-158). E-value:
                     1.3e-16. Score: 53.2. Matches aSDomain:
                     nrpspksdomains_CES90_RS44120_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022072.5"
                     /locus_tag="CES90_RS44120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SRPBCC family protein"
                     /protein_id="WP_229914515.1"
                     /transl_table=11
                     /translation="MGGAHRSRGAPVLPHHRRLTTRKTGETTLAHIHKEFLIASAPDNV
                     WAALRDVSGIHRRLAPGFVTDTRLEADTRVVTFANGVVVHELLVDIDDETRRVAYAVIG
                     GSLAPKHHHASMQVFAGGEDHSRFVWISDVAPDDLAGPIAEMVDQGARVIKQTLETQAT
                     ADN"
     aSDomain        6716..7099
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CES90_RS44120_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="1.30E-16"
                     /label="CES90_RS44120_Polyketide_cyc2.1"
                     /locus_tag="CES90_RS44120"
                     /protein_end="158"
                     /protein_start="30"
                     /score="53.2"
                     /tool="antismash"
                     /translation="HIHKEFLIASAPDNVWAALRDVSGIHRRLAPGFVTDTRLEADTRV
                     VTFANGVVVHELLVDIDDETRRVAYAVIGGSLAPKHHHASMQVFAGGEDHSRFVWISDV
                     APDDLAGPIAEMVDQGARVIKQTL"
     gene            complement(7312..>8037)
                     /locus_tag="CES90_RS44125"
                     /pseudo=""
     CDS             complement(7312..>8037)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1130: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477235.1"
                     /locus_tag="CES90_RS44125"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS256 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="DAVNVEVRDGQVANRPVYIALAVTADGQRDILGLWIGDGGEGAKY
                     WQQVLTEIKNRGTRDVLMLVCDGLSGLPDAVNNVWPRTVVQTCVVHLLRNSFSYAGRQD
                     WAKIAADLKPVYTAPTEDAATTQFLQFSEKWGTKYPGIVRLWENAWAEFVPFLQFDVEI
                     RKIICTTSAIESVNARIRKAVGARGHFPTDAAALKCVYRAVISLDPSGKGRQRWGRRWK
                     PALNAFDIAFDGRLTAARD"
     gene            8129..8743
                     /locus_tag="CES90_RS50745"
     CDS             8129..8743
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CES90_RS50745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_229914514.1"
                     /transl_table=11
                     /translation="MDLPLGEQSVVIRLTVRRFICGAANCLRRMFVEPFAQLTAPYARF
                     TTRLNHILERIGLTLAGRAGARLAAQVGALGQPACVQLFLPLHLCLEIPVPGFGGRGFG
                     FGGEPVLDDGVGVRVVDTAGGGEQLRDALPLADFGGAAFVVGQVLAAAFEVPLQPGFVE
                     GGRGLGGGHAGGASADRAAADLRPFDRIAGRGRGGRRDAGT"
     gene            8976..9821
                     /locus_tag="CES90_RS44140"
                     /pseudo=""
     CDS             8976..9821
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011026834.1"
                     /locus_tag="CES90_RS44140"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGTAPWIVSDELWDRLESLLPRRGRRLRYPSRKPLPDRKVLCGIL
                     YVLHTGIQWEYLPQELGFGSVMTCWRRLRDWNEAGVWQRLHEVLLAELKAAAKLDWSGC
                     VVDSSHVKAPKGGATQARRRSTGAGPARNTI"
     gene            10001..10531
                     /locus_tag="CES90_RS44145"
     CDS             10001..10531
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.5"
                     /locus_tag="CES90_RS44145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_189788466.1"
                     /sec_met_domain="phytoene_synt (E-value: 2e-11, bitscore:
                     42.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.2e-08,
                     bitscore: 33.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQRDVDFRDFATYAELRQWATQMTGSPAYGVMWAMAGTELTEAQS
                     LVREFAELCQLSDVLCDLSEDLDDGRLYLPLEDLDQLGVHPADVKAKRWTPAMADLIAF
                     EAARVRDRLPALAAELEHTPVGTFAQAFGEHCRLLLAGVLAAGQDVLHRPVQPPMGDFL
                     NAWRPLMRDVIPC"
     gene            10550..11524
                     /locus_tag="CES90_RS44150"
     CDS             10550..11524
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669514.1"
                     /locus_tag="CES90_RS44150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_189788465.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-47, bitscore:
                     161.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIAVTPVGGTHIPLLEAELLRWVGSGDSLLEVACLDALFPPGKL
                     LRPILCMESAKAVGGDMNQVLAFAAGIECLHVASLIHDDIIDQDPVRRGRASTAEQYGL
                     AEALVAGDGLSMAGIAAMLSGGPAERVLHAARVTVDALRHMCQGIMRETGIRGDLTCGV
                     PAVLNVMQAKTAALTGAACQAGAILAGATLEQDRALRRYGEQLGMAFQIRDDLLPYTAE
                     DQITGKTAISDVANLQPTLPVLLAYEVADKADRDRLTTVFHGDTDPVTAHRDILAVLTR
                     TGALTKAAQMASSRAEQAHVALTGLPDALRLAELATSAADRQR"
     gene            11629..12213
                     /locus_tag="CES90_RS44155"
     CDS             11629..12213
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016467902.1"
                     /locus_tag="CES90_RS44155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_189788464.1"
                     /transl_table=11
                     /translation="MNTSRILKRSALAVAGAAGVLAVAVTVIPQEETPAAQSVKSPPLL
                     AALTQAASLPFACQKAIFKTGDQFATTRYAIPDEFWNAAVAALGSLTETERAELTRPAC
                     AAWNSWATANSTAVTGELDNRYRNAPLPVCNKFTVATVGTVRKFSPNTPAAARGLEKVV
                     KKVWTEAMTKLSATASDATCRTSYSTAKTAW"
     gene            complement(12258..12533)
                     /locus_tag="CES90_RS44160"
     CDS             complement(12258..12533)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CES90_RS44160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_189788463.1"
                     /transl_table=11
                     /translation="MASLVVALERNRRLTARGRQLEKRLSETLGETAGKESGLGASADI
                     DELQRRITLLEQHLADIKGQLDERTEELDAARAANRELTRALNRAR"
     misc_feature    12528..12538
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: strong, score: 22.05"
                     /tool="antismash"
     gene            complement(13129..14199)
                     /locus_tag="CES90_RS44165"
     CDS             complement(13129..14199)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557232.1"
                     /locus_tag="CES90_RS44165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="chitinase"
                     /protein_id="WP_232791377.1"
                     /transl_table=11
                     /translation="MRGFFRCRGHAGSLAPGHISIGLFAVPAVLVFVVLAGLSALALPS
                     VLKTEHRTDQVPPASGAGPRFAPYVNAWATAPTPPGVKDLILSFIVADDGRCKPEWDAD
                     VPVAEPRVRDRIAATRRAGGDVRVSFGGADGTELATACTRVPQLIAAYGSVIDHYDLTE
                     VDFDIEDEALSDPRARARRAEAIAELQRTHEGLDVSFTLPVLPTGLTDDGMALLTEARE
                     SGVRVSTVNIMTMNYGEALRGDMGGYAMQAATNAQAQVRTVLRLTDAAAWRALAVTPMV
                     GVNDVAGEVFTLEDAAQLADFAADKRIGGLSMWSAERDRPCLGESKREPDHACSGVQQR
                     PGAYTAALRRATEASA"
     gene            14371..14763
                     /locus_tag="CES90_RS44170"
     CDS             14371..14763
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CES90_RS44170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_189788462.1"
                     /transl_table=11
                     /translation="MDLQLGTAECAPTLSLQREPCQQGRQQPQPEQPCGRPVFVDPTGR
                     RARLIGCCAVVAGTALVGYAAIFCVGLSGGTPFAPRTLVPGTAGDADTTGAVGSRATSS
                     AQPPSPTARTARTSWDGAGMLRPEPR"
     gene            14904..17114
                     /locus_tag="CES90_RS44175"
     CDS             14904..17114
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009715351.1"
                     /locus_tag="CES90_RS44175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional polysaccharide
                     deacetylase/glycosyltransferase family 2 protein"
                     /protein_id="WP_189788472.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.3e-33,
                     bitscore: 115.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLNGYLRAEIGADPPGRGTSDSRGAVPGSTFPVFHRAVPRGAVS
                     VGTPPRSRAFDAARLRAATARRGSYQRTVPEEVLTGGPVLTFAADGKVTSHRIPRNTIA
                     LTFDDGPDPEWTPKVLEVLRKHDVSGTFFVVGRMAARHPQLIRRILESGNEIGVHTFSH
                     PDLGSHSTGRIDRELARTQLVLAGAAGVTSSLFRAPYTSYVTVLDDRDWAVTRYLGRKG
                     YISTFIDKDSEDWRQLAAAKIVRNAMPKAGAGASVLFHDAGGDRAQTVRALGMYIKEMK
                     RRGYVFTTVTGALSAPSAVHKAGTVRLWEGRAMVAAVSLTGAVMPALNVLLLAVGAAVI
                     ARFITMPVLAAWHHRSRNRRSWTWGPPVTEPVSVIVPAYNEKECIAHTITSLAASRHPI
                     EIIVVDDGSTDGTADIAEAMKLPSVRVIRQRNAGKPAALNRGVANARHDLIVMMDGDTV
                     FEPGTVGELVRPFADTRVGAVAGNAKVGNRNSVICAWQHIEYVMGFNLDRRMYDLLRCM
                     PTIPGAIGAFRRTALVDAGGMSEDTLAEDTDITIALHRAGWRIVYAEHARAWTEVPNSV
                     GQLWRQRYRWSYGTMQALWKHRRSVVDRGSSGRFGRVGMPLVVLFQILMPLFAPLIDLF
                     MLYGIFFFDPVRSLAAWASVLLVQLLCALYAFKLDGERYRCLFLLPLQQIVYRQLMYLV
                     LLHSCATAVTGARLPWQKLRRTGEVDAPPRPRVVTGQVPGNG"
     gene            17276..17446
                     /locus_tag="CES90_RS52260"
     CDS             17276..17446
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039373.4"
                     /locus_tag="CES90_RS52260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6192 family protein"
                     /protein_id="WP_373313635.1"
                     /transl_table=11
                     /translation="MVNEAQQQKDEEAREAFHRDSPVAPTLRHIQRSIEFIELVGVFHA
                     LVTAAGGSSCG"
     gene            <17942..19149
                     /locus_tag="CES90_RS44180"
                     /pseudo=""
     CDS             <17942..19149
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_329449158.1"
                     /locus_tag="CES90_RS44180"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKDLSTSVVALLVSEACNIGLAPVVNPAHEALTRARLVHVDQSYL
                     RADTVAAANARLMAAQAEVPIVKFWGEGLLASVDGLRFVVPVRTVSAAPSPKYFGLKRG
                     ITWLNAVNDQVAGIGQMVVPGTPRDSLHILEALLNLDGGVKPEMVATDNASYSDMVFGL
                     FKILGYNFSPRFRDLDDQRFWRATMPGVETGTYGAVEDLARNRVNLSKVITHWPDMLKV
                     AGSLVTNQVRA"
     gene            complement(19250..19834)
                     /locus_tag="CES90_RS44185"
     CDS             complement(19250..19834)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040282.1"
                     /locus_tag="CES90_RS44185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DinB family protein"
                     /protein_id="WP_189788461.1"
                     /transl_table=11
                     /translation="MIDEFAKDNLHGRLRRDREALLWKLDGLSEYDARRPLTATGTNLL
                     GLVKHVASVEARYFGEVFDRPSPEPLPRWQDSDGSDLWATEDETRDQIIGFYRRTWEHS
                     DATINELPLDAPGHVPWWPEPYADTNLFAVMVHVLGESIRHAGHADILREGLDGRTGLR
                     AEHEKQIDEEARAAYCAKIELAARTAAPIKA"
     misc_feature    complement(20098..20111)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 22.57"
                     /tool="antismash"
     gene            complement(20409..20954)
                     /locus_tag="CES90_RS52265"
     CDS             complement(20409..20954)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012335.5"
                     /locus_tag="CES90_RS52265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_373313634.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.9e-22, bitscore:
                     78.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNERTRVTVIGDGAVGLMAVLSAKRLGAEQIILMGRHHARTDLGR
                     EFGATDVVSARGEEGIEQARELTGGDGTHVVLECVGNTPAYEQSLGIVRHGGVISRVGV
                     PQCEDDPVGFGSLFGHNIRLAGGPAPVRAYIEELMPDILNGTIEPGKVFDATTALDGVP
                     VGYQDMADRNTLKVLINP"
     gene            complement(20920..21438)
                     /locus_tag="CES90_RS52270"
     CDS             complement(20920..21438)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019845.5"
                     /locus_tag="CES90_RS52270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alcohol dehydrogenase catalytic domain-containing
                     protein"
                     /protein_id="WP_373313633.1"
                     /sec_met_domain="ADH_N (E-value: 2e-17, bitscore: 62.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYGAGDVRVENVPDSIIKLPTDALVRITSSCICGSDLWPYGSMKP
                     EDGPARMGHEFIGVVEDTGSEVTTVKRGDLVVAPFAVSDNTCPFLPRGSAHLLRPPAGE
                     LLGRRAGGGRPGRSGPRPARRRHPRQAPRRPGLRLHPVPADAHGRPRHRLPRRRRGRRE
                     RAHPRHRDR"
     misc_feature    complement(20977..20979)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 accgcctctc cgccctcgtc ggcgggctgg tcgacgtcac caccgcggac cactggtggc
       61 tgtgcggacc ccacggcatg gtccgcgacg cccagcgggt cctggccggc ctgggggtgc
      121 ccgacacccg tgtccaccag gagctgttct acgcggacga cgcgccggta cggcagacgc
      181 ggcgcgagga agccgctgcc gagggtccgg tcagcaaggt caccgtcacg ctcgacggcc
      241 ggtccaccac tgccgcgctg ccgcgcgcgg ccacggtgct ggacggcgcc cagaagatgc
      301 gccccgacct gcccttcgcc tgcaagggcg gcgtgtgcgg cacctgccgc gccctggtca
      361 ccgaagggga agccgacatg cgccgcaact tcgccctcga agccgccgag gtcgaggccg
      421 gctatgtgct gacctgccag accttccccg tctccgagac gctgaccgtc gacttcgaca
      481 gctgaggaag cccatgtccg tccacctgga agtcgccgaa ggcgtcggca cgatccgcct
      541 cgaccgcccg ccgatgaacg ccctcgacat cgccacccag gaccggctcg gcgagcttgc
      601 cgcggaggtg accgagcgcg acgacgtccg ggcggtcatc ctgtacggcg gcgagaaagt
      661 gttcgcggcc ggcgcggaca tcaaggagat ggagctcgtc gaccacgcgg gcatggtcag
      721 gcgctcgcgc ccgcttcagg acgccttcac ggccgtcgcc cgcatcccca agccggtcgt
      781 cgccgcgatc accggttacg cactcggagg cggctgcgag ctggccctgt gcaccgacta
      841 ccggatcgcc gccgacaacg ccaagctcgg ccagcccgag attctcctcg gcctgatccc
      901 cggcgcgggc ggcacccagc gcctgtcccg gctcgtgggc ccctccaagg ccaaggacct
      961 cgtcttcacc ggccggatgg tcaaggccga tgaggctctc cggatcggcc tggtcgacct
     1021 cgtggttccg gccgccgagg tgtacgagca ggcgcgggcc tgggcctccc ggctggccaa
     1081 gggccccgca ctcgccctgc gggccgccaa ggagtcgatc gaccagggcc tggagaccga
     1141 cctcgacacc ggtctcacca tcgagcgcaa ctggttcgcg ggcctgttcg cgacagagga
     1201 ccgcgagcgg gggatgcgca gcttcgtcga ggaaggccct ggcagggcga cgtttctctg
     1261 aatactcctt ggaatggttg gctgtgtcgg tttccgcggg agtcgttcgg cgatgacttc
     1321 aggcgcagac ctgacgaatc gtcactcccg cctgtcagaa ggcggggcgt ccgtgccaga
     1381 accagacagt gaagggtggg tacgcgtgga ccacggtgag gacgagatcc tggctgaaga
     1441 gcttgctgct ctgggggccg tggtcggggg cagccgtcgc ttgacccggc ttgtggccaa
     1501 actgatgagg aagaatgtcc atgagatcga cctcgagatg cccctgccgt tcgatgatgc
     1561 cgtcagacgt gtcgccaaag tgcttggtca cgccggacga gcggtggggt ccatgcatgt
     1621 cgagcctggc gtggaccagg agacgatccg tgtcgtcacc agcggtggcg cgggcggcat
     1681 gaatcccgta gtggttactg cgctggtgac aaagggcggg atgggcagct cgaaggtcag
     1741 gcttcgtgca gctgccaagg aaggcttgat caagcagcga gcgggcgaga agaccgccgc
     1801 ccgtcttgcg gggtggctga gcgagtagag cagatccggc atgaggtgct gcacacggcc
     1861 aagatccgga tcgtgtactg cggaagacgg gggccacgac ggtgtcgcgg caacgtcgtt
     1921 cgccttcccc gtttcacatt ccagcgtcgt ccagcgcgag aggacgccct gaagatgaac
     1981 cgttccgggt ctgatggagg ctcgattccc tgagaggatc gagtcatggg caactcggcc
     2041 gccattgacg acacggggtc ggtacggccc gcgatcagct catgccgcgg gctcccggtc
     2101 gtcaagtccc atacccgcat ttccccgtcc ctgcttcctg caacggcgac cgttcgcccg
     2161 ccgacaaccg ccgtcgtcac cgccgtcaca ggaccaccgt ggccggcgaa agcacgcagg
     2221 aaccgagggt cggcagcaga gccgctcgcc caggccggat cacactccag acccggctcc
     2281 ggatcgggct gtcccggcac atctgcgctc ccgaaccatg aggccagctc cgcatcaccc
     2341 agccgtgccg catccagcgc cagtatctgc cgtcgctgaa ccggtgccac cgtctggtca
     2401 cttccgccga agtccggtac accgccgcca cggcccgact ccacgggtcg gccatccggc
     2461 ccaacaactc gatgacacga gtcggttcgg tggtgagcag cagaccggga tccgacagca
     2521 aggaacgcac ttcaagcgga atgtccgccg gtctttcgct cacggcaccg agaacaggat
     2581 ccggcgtgga cgccgagaca tccgccgacc acgcgatgcc gacgagcctg ggcaggggat
     2641 cgtgcacgga agatctgcgc agatgaagcg gctcggccgt aacgccgccg aactcaccgc
     2701 gctcgccgac cacctcaccg cccacggcct ggtcctggag atgctcgccg ggcccgagaa
     2761 gctgctgttc gcgttcttcg cggcgacggc ggagaccgag caggagaaca tccgggtgtc
     2821 ggccctggag aggcgcgaca ccgcgacccc caagggcaag cacggtggtc ggccgcaggt
     2881 cgtcaccgac gacatgctcc acaccctgcc ggagcgccgc caggggcaag gccggcgtct
     2941 gcgagccgtg tgccgggggc cgaggcgggt gcccgggccg gagttcacag gagctggtcg
     3001 agggcgatgg cgaaagcggt gctcgccacg cgcgtggggg cttgtgaccg tgcatgacag
     3061 tgcttcagcg cggattcgat ggtggacgag atgtcctcga agatcgactc atcggagatt
     3121 tccaggttgc cctgcatcag gagggcgaag gtgcgtgcca tgccgcagtt ggcgatgaag
     3181 tccggaacga cggcgacgct gtggtccgcg tgttcgtaga cggggccgta gaagatctcg
     3241 gggtcggcga acggcacgtt ggcgccgctg gcgatgactt cgaggccgtt cgccgtcaga
     3301 cggtcgacgt gttcgcgtgt gacagacgtg acgccgcgca ggggaagaag acctccgcgc
     3361 cggtgtccca gatggtgtcg ttgacctggt cgaagggaac gaggtcatcg gcccgcaacg
     3421 tgttgccctg cttggcgagg aacagttcgc ggacctgcgc accggcgacc ggtggcagcc
     3481 cgccgatggt cctcctgggt caggccacga ctcaactcgg aacggccgtt ccaagatagc
     3541 gggcgaggaa gtaacccgga accctcgttt caagttggcg aagtgaggca tgcatgccgg
     3601 acatcaagca cttcgacccg gacgcggccc tggagacggt gtgccgcctg ttctggcgac
     3661 agggtgttgc ctcgaccggg atccaggacg tggtgaccgc gaccgggctc aaccgctcca
     3721 gcctgtatgc cacgttcggc ggcaagcagg agctctacct cgccgcgctg cgccgctaca
     3781 tggagcaacg gtctcagccg atgttccggc gcctcgcgca ggacgagcgg ggactgccgg
     3841 ccgtctccga gttcttcgcg ggcctgatcg aggcgcgctg ctcgggcgag tacgcccgct
     3901 ggggctgcat ggtctccgac gcgcacgccg gggccgagaa cagcgatccc gaggtgcgcg
     3961 ccgtcctgga ccagcatcac cgggagctgc gggacgcgct gcacgcggct ctcgtcaccg
     4021 ccgatgctca gggacagctt gcccctggct gcgatccggg cgcctgcgcc gacctgctgg
     4081 cgctgctcgc gtacggcgtc aacctccgct cccgcgccgg agcggacgca cgcgacctga
     4141 acaggacggt gaccaccgcc ctcgcctcgc tcggcgcccg ggcgacgccc tgatgactcg
     4201 taccggccat cgcaccggtc atcgccgggc cctgcgttcc gcctcttcct tcaccgcggc
     4261 gagcgatccg gcgaccgttg cctcccagcg gggggctacc aggccacccc accactggcc
     4321 gaggcgccac aggtccgtag agagttcacc ggtgtattcc agccgggtcc tcgacccctg
     4381 ctcgccgagc tcgaaggact cggtgacggc cgggacgggg ccgcgtacca gccggaagtc
     4441 gacccgctcg gggctgctcg gcctggggca ccggcgcatt gccatgatca gcggcccgga
     4501 tcaccccttc tgcctcgccc ggctgttcgg tcactcgtcg gctctcgcgg aagccggcct
     4561 gccgttggaa cccggcccgg tggtaaagac ccagctcacc cgcgagcacg gatacaccgc
     4621 cgcgcgggag ctgctgtccc gctccgatcg tcccaccgcg gtgttcaccg cgaacgacat
     4681 gcaggcgctc ggtgtctacc aggccgcgcg cgagctcgga ttgcgcatcc cgcacgatct
     4741 cagcgtggag ggcttcgacg acgtaccggc cgtggcctgg atggacccgg cccctgacca
     4801 cggtccatca gccgttggcc gagatggcgg cagctgccac cgagctgacc ctggcgctcg
     4861 gccggggtga gcaggtgccg caggtggggt tggagatcgc caccactctg accgtccggg
     4921 agagcacggc tccgccgaaa gcggcgtgag tgactgagga gcagccgcgc gagcggtgga
     4981 tgtccagcga cgcccggcac cgatttgctc ccggaaccgg agcccggaaa ggctcaggtc
     5041 ccgggagcga gggtcatccg gcggtcagag tggtccactt ctggttggag ccgccgtggc
     5101 agtcccacag atggagctgc gtgccgtcgg tcgtgcgcat cgtgcggcgg agcaccgttg
     5161 gcgatcgtcc gccactacat cgagcagcaa aaacgtccgc tccaacgtgc acgtcagagc
     5221 agtcttgaga tgcattcatc cccggcgtga acaccggggc tttctgcaag agtcccgata
     5281 attccccagg cgaagacgaa gcaacggaga gcgtcaaggt gtccgagggg cgagcaggcg
     5341 tcgcagtgcc gtcggtgtac ggcccaggta ctggcgtatg gtcctgctca tgtgcgcctg
     5401 gtcggcgaag ccgaggtctg cggcgagggc gccgaggctg ttctcgccct cctccaggcg
     5461 gtcgagggcg cggccgatgc ggacgcggtt gcgatattgg gtcacggaca cccccagttc
     5521 gcggctgaag gatcggctca ggcggtaggg cgagacgccc agcacttctg cgagcgggag
     5581 cagtccgttc gaggccgggt ggccttcggt gatcgcctgg cgtgccgccg caacgagagc
     5641 cgcttggttt ccctgggctt gtgcgctgag tggtgtgggc cctgagacga cttggcggac
     5701 ggtggtggcg agcaggccga gcaattcttc ggtcagcgtg tagtcgacgt ctccggtccg
     5761 cgcggtcgcc aggagccggc gatgggtgag gtcgaggcgg gcatcgacgt acacgttctg
     5821 ggtggccagg cgcgcgacgt cgccggccat gacgtgccag agcgccggcg tcaggctaat
     5881 ggatgtgcag tcgtcgcctc cggcgggatg ggcgaagtgc tcttcctcac ccggcacgcc
     5941 gacgtaggcc attgtcgagt cgatgtcggc ggcggctccg gctacgcgcc tgcggaaccg
     6001 gccacggcac acgagcacca accggtagtc ctcacgtact tcggcctccg accagcgcgc
     6061 atggtcgtcc tggcatgtca cagccgtgat gctgaaatcg agtcgggtag cgagagtggt
     6121 ggttgagagc acctttgcac gctacgccga gggtctgaca atcaccctcg caaggatgtt
     6181 caagacgggg acctactgcc acgagcaggc tggtcgacgt gccccggccc ggccgcccgg
     6241 cccagtgcac ccgcgctgcg gcgtcggcac gggcggggca cgtcacacat caccagcacc
     6301 catacgaagg ggtcattggc atgcccgctc tcgcggagtt caccgcggtc gtcatcgact
     6361 gcgcagatcc ggccatgctc gccgagttct acaggaaggc caccggctgg gaaatcacct
     6421 acagcgacca ggacttcgcc tccctgggca acggcggtcg aatgcaaatc gccttcgtgc
     6481 gcatcgaggg ctaccaggcg ccgggctggc ctgacgcccg caagcacgcg cacctcgact
     6541 tcaccgtcac cgacttggag agcaccgcca aggaactgct cgccctcggg gcagcaaagc
     6601 ccgagttcca gaccggcgag ggcaagtggg tggtgctcac cgatcccgag gggcacccgt
     6661 tctgcctcac caccggcgac tgaccacccg gaaaacagga gagaccaccc tggctcacat
     6721 ccataaagaa ttcctgatcg cgagcgcccc cgacaacgtc tgggcggcac tccgcgacgt
     6781 cagcgggata caccggcgcc tggcacccgg cttcgtcacg gacacgcgtc tcgaggcgga
     6841 taccagagtc gtgaccttcg ccaacggcgt cgtggtgcac gagcttctcg ttgacatcga
     6901 cgacgaaacc cgtcgggtcg cttatgcggt gatcggcggg tcactggccc ccaagcacca
     6961 ccacgcgtcg atgcaggtct tcgcgggcgg cgaggaccac agtcggttcg tctggatcag
     7021 cgatgtggca ccggacgacc tcgcgggccc tatcgctgag atggtcgacc agggagcacg
     7081 cgtcatcaag cagacgctgg agacccaagc cactgcggac aactgaccga gcggccggga
     7141 agtgcggcgc ggctccggca ggggtctggt cccgatggag ccgcgtccgc aatccccgtg
     7201 ggaaagctcg tgaacgtctc ccaggggaat atcgcgaccg ttcacacggg ctcgcgtgag
     7261 accgcgtacg cgggtctgta aaggcttctg tggaactcgg tttggtggtg gtcagtcgcg
     7321 ggctgcggtg aggcggccgt cgaaggcgat gtcgaaggcg ttcagggcgg gcttccagcg
     7381 gcggccccag cgttggcggc ccttgccgga ggggtccagg cttatgacgg cgcggtagac
     7441 gcacttgaga gctgccgcgt cggtggggaa gtgcccgcgg gctccgacgg ccttgcggat
     7501 ccgggcgttg acgctctcga tcgcgctggt cgtgcagatg atcttgcgga tctcgacgtc
     7561 gaactggagg aaggggacga actcggccca ggcgttctcc cacaggcgca cgatgccggg
     7621 gtacttcgtc ccccatttct cgctgaactg caagaactgt gtcgtggccg cgtcctcggt
     7681 cggcgcggtg tagacgggct tgaggtcggc ggcgatcttc gcccagtcct gccggcccgc
     7741 gtaggagaac gagttccgca ggaggtgaac cacgcaggtc tggaccacag tgcggggcca
     7801 cacattgttc accgcgtccg gcagcccgga caggccgtcg cagacgagca tcagcacatc
     7861 acgggtgccg cggttcttaa tctcggtgag gacctgctgc cagtacttcg caccctcgcc
     7921 gccgtcgccg atccacagtc cgaggatgtc gcgctgcccg tccgcggtga ccgccagggc
     7981 gatgtagacc ggccggttgg cgacctgccc gtcgcggacc tcgacgttca cggcatcacg
     8041 gtcgatgtgg tggcgagagg ccgggcggcc ggggcggcgt gtccggactg cggtcgcttt
     8101 tcggaccggg tgcacgactc gcaggttgat ggatctcccg ctcggtgagc agagcgtcgt
     8161 gatccggttg acggtccggc gtttcatctg cggcgcggcc aactgcctgc gccgcatgtt
     8221 cgtcgagccg ttcgctcagt tgaccgcgcc gtacgcgcgc ttcaccactc ggctcaacca
     8281 catcctggag cgcatcgggc tcacgctcgc cggacgggcc ggcgcccgcc tggcagccca
     8341 agtgggcgcg ctcgggcagc ccgcctgcgt gcagctgttc ctgccgctcc atctctgtct
     8401 ggagatcccg gtccccggct tcggcggccg cggctttggc ttcggtggcg agcccgtgct
     8461 ggacgacggc gtcggcgtcc gggtcgtaga caccgccggt ggtggcgagc agctacgcga
     8521 tgcgctccca ctcgccgact tcggcggggc tgcgttcgtc gtcggccagg tcctcgcggc
     8581 cgcgttcgag gtgccgctgc agccgggctt cgtcgagggc ggccgcggcc tcggtggcgg
     8641 tcatgccggt ggcgcgtcgg cggaccgagc ggcggccgac cttcgcccat tcgaccggat
     8701 agcagggcgc ggccgcggcg ggcgccggga cgcagggacc tagggacgca gggacgcagg
     8761 gacggcggct ggaccgggga acatgggtgc tcacacgagc ctcccagccg tcgcggaaac
     8821 ggtgacggga aatccggctg ccgcgcggtg ggcgcggcag ccgtagacag gttcatagca
     8881 gccacgaatt ccgtgtggct aacagcggct gacacaaaga ggtggatcgg cgccgatgac
     8941 cgtgtccggg gcgggagttg accgttcggc cgggtgtggg gacagcgccg tggatcgtgt
     9001 cggatgagct gtgggaccgc cttgagtcgc tgctgccgcg gcgtgggcgg cgcttgcgct
     9061 acccgagccg caaaccgctg ccggaccgga aggtgctgtg cgggatcctg tacgtgctgc
     9121 acaccggcat ccagtgggag tacctgcccc aggagctcgg cttcggctcg gtcatgacct
     9181 gctggcgcag gctgcgggac tggaacgagg ccggtgtctg gcagcggctg cacgaggtcc
     9241 tgctcgccga gctgaaggcg gcggcgaagc tcgactggtc gggctgcgtg gtcgactcct
     9301 cccacgtcaa ggcgccaaaa gggggagcca cacaggcccg tcgccggtcg accggggccg
     9361 ggccggctcg aaacacgatc tgatcatcga cgggaacggc gcgccgctcg cggtcatcct
     9421 caccggcggc aaccgcgggc gacatcaccc agctgctgcc gctcctcggc gcgatcccgc
     9481 cggtccgcgg acgggtcgga cgtccccgct gcacgcccga ctcgctgttc gccgaccacg
     9541 gctacgacca cgacatctac cgcgaccagg tccgttcccg ccggatcctg cccgtcatcg
     9601 cccgccgcgg cacgccccac ggcagcggac cgggtgtcta ccgcggggtg gtagagcgca
     9661 cgttcgcctg gctgcactgc ttccgacgtc tccgggcgcg ctgggaacga cgggccgaca
     9721 tccatgacat cacgccaccg aggtcagtag aggctgttgt cattccgatc ttgtcgggcg
     9781 gcacgcgaac atatgtccca acccagaacc cgcgcgggtg atcttcgtgg ggggctgcgc
     9841 acggaaacag ggcctgctgg caactcgggg gaacgaaccc gcttcgggca tctggaggcc
     9901 cttttgcccc agcctgtcgc gtccgtgcta tcggagtcca actctcgcgt gccgctgtgc
     9961 gattgcctcg cacgctggtt cggcaacgca ggcgaccgcg atgcagcgcg acgtcgactt
    10021 ccgcgacttc gccacctacg cggaactgcg ccagtgggcc acgcagatga ccggcagccc
    10081 ggcctacggg gtcatgtggg ccatggctgg caccgaactc acggaagcgc agtcgctggt
    10141 gcgtgagttc gccgaacttt gccagttgtc cgacgtgctg tgcgacctgt cggaggacct
    10201 cgacgacggc cgcctctacc tccctcttga ggatctcgac cagctcgggg tgcaccccgc
    10261 ggacgtcaag gccaaacggt ggacaccggc catggctgac ctcatcgcgt tcgaagccgc
    10321 gcgcgtcagg gaccggttgc ccgccctggc cgctgaactg gaacacaccc ccgtcggcac
    10381 cttcgcccag gcattcggcg agcattgcag gctgctcctg gccggcgtgc tggccgcagg
    10441 ccaggacgtg ctccaccggc cggtccaacc acccatgggt gacttcctca atgcgtggcg
    10501 ccccctgatg cgcgacgtca tcccctgctg accattgaaa ggacgtgtca tgcccatcgc
    10561 cgtgacccca gtcgggggca cacacattcc gctcctggag gctgagctgc tgcgctgggt
    10621 gggcagcggc gacagcctgc tggaggtagc ctgcctggac gctttgttcc ccccgggcaa
    10681 gctccttcgc cccatcctgt gtatggagtc cgccaaagcc gtcggcggtg acatgaacca
    10741 ggtgctggcg ttcgcggccg gcatcgaatg cctgcacgtc gccagcctca tccacgacga
    10801 catcatcgac caggacccgg tacgccgcgg gcgggcctcc accgccgagc agtacggcct
    10861 cgccgaggcc ctggtagcag gtgacggact gtcgatggcc ggaattgcgg ccatgctcag
    10921 cggcggcccc gccgagcgcg tactgcacgc agcacgggtc accgtcgatg ccctgcgtca
    10981 catgtgccag ggcatcatgc gcgaaaccgg aatccgcggc gacctgacct gcggggtacc
    11041 cgccgtcctg aacgtcatgc aagccaagac cgccgctctg accggcgccg cctgccaggc
    11101 cggcgccatc ctggccggag caaccctgga gcaggaccga gccctacgca ggtacggaga
    11161 acagctcggc atggccttcc agatccgtga cgacctgctc ccctacaccg ccgaggacca
    11221 gatcaccggc aagacagcca tcagcgacgt cgccaacctg cagcccaccc tgcccgtcct
    11281 gctcgcctac gaagtggccg acaaagccga ccgcgaccgc ctgaccaccg tattccacgg
    11341 cgacaccgac cccgtcaccg cacaccgaga catcctcgcc gtgctgacac gcaccggcgc
    11401 cctcaccaag gcggcccaga tggcatcctc ccgcgccgaa caagcacacg ttgcactcac
    11461 cggcctgccg gacgccctgc gcctcgccga actggccaca tcagcagccg accgtcagcg
    11521 ctgagtaggg ccgggactgg cgcggtggct gatgctccgt ttccagttcc cgctcctggt
    11581 ctgcaccggg ctggccgctc agccctcaag tacaggagac ctgcgctcat gaacacctcc
    11641 cgcatactca agcgctccgc tctggccgtg gccggggccg ccggtgtcct ggcggtggcg
    11701 gtgactgtca tccctcagga ggagaccccg gccgctcaga gtgtgaagtc ccctccgctc
    11761 ctggccgccc ttacgcaagc ggcttcgctg ccgttcgcct gccagaaggc gatcttcaag
    11821 accggggatc agttcgccac cacccgctac gccatcccgg acgagttctg gaacgccgct
    11881 gtcgccgctc tgggcagtct gaccgagacc gagcgggccg aactcacccg gcctgcctgt
    11941 gcggcgtgga acagttgggc caccgccaac agcaccgccg tgacgggtga gctcgacaac
    12001 cgctaccgca acgctcccct gccggtgtgc aacaagttca ccgtcgccac tgtgggaacg
    12061 gtcaggaagt tctctccgaa caccccggcg gcggcccggg gcctggaaaa ggtggtcaag
    12121 aaggtgtgga ccgaggccat gaccaagctt tccgctacgg cctccgacgc cacctgccgc
    12181 acctcctaca gcaccgccaa gaccgcctgg tagccaccgc ggccctggcc cctgtcctcc
    12241 gaggattcca cgccttctca gcgggcccgg ttcagtgccc gggtcagttc ccggttggcc
    12301 gcccgcgcgg catcgagttc ctcggtccgc tcatcgagct ggccctttat gtcggcgagg
    12361 tgttgttcga gcaacgtgat gcgacgttga agctcgtcga tgtcggcgga cgcgccaagg
    12421 ccggattctt tcccggcggt ttcaccaagg gtctcggaga gacgcttctc caactgtcgg
    12481 ccccgggctg tcagccgtct gtttcgctcg agcgcgacga caagagatgc catgtcacac
    12541 cactgccacc aaaaccccag agaacccgac gatctcctca tcgcgcagcg gacctcaacc
    12601 aggtccgcgc cgacctcacc gccttgtagg ggcggctgcc ctactcggtg gagccgatgg
    12661 aggcccgggg gcgtccgagg gctactggtt cgcaacgtcc cgcgcgtacc ctgactcgcc
    12721 gggctggtcc cagcaggaac agcagcaggt cgccgcgctg cgggagaagg cacgcgacgt
    12781 caccggggtg atactcacgc acgccttctg ggacggggtc gcggcaccgc atcgtcccga
    12841 cgcccgcagc cagctcaagt acgccctcga tgtccacgag gacagccgag atcaggaggt
    12901 gtaaccgtag cggcccctcg ggggcgtgtc ctgagggcgg acgtgctggg cgtacctgcc
    12961 caacgaggcg acagctgcga ctggttgggg acaggatggc ggcagcgatc gcggggaggg
    13021 ccggatgagg ctgaccattg ggcgatgcac aacctgaatc tgcaggtcgg ggggctggcg
    13081 tgcgtcgcga tcgggatgct cgcgctggtc ggcgccgtgt cacgtggatc aggccgatgc
    13141 ctcggtggca cgtcgaagcg ccgccgtgta cgcaccgggc cgctgctgga caccgctgca
    13201 ggcgtggtca ggctcgcgtt tcgattcgcc gaggcacgga cggtcgcgct cggcggacca
    13261 catggacagc ccaccgatgc gcttgtctgc ggcgaaatcg gcgagttggg ccgcgtcctc
    13321 caaggtgaag acctcaccgg cgacgtcgtt gacacccacc ataggtgtca cggccagagc
    13381 cctccatgcg gccgcgtccg taaggcgcag cactgtgcgc acctgagcct gggcgttcgt
    13441 ggccgcctgc atcgcgtacc cgcccatgtc gccgcgcagc gcctcaccgt agttcatcgt
    13501 catgatgttc acggtcgaca cccggacgcc gctttctctg gcctcggtca gcagggccat
    13561 gccgtcgtcc gtgagcccgg tcggcaggac tggcagcgtg aaggagacgt caaggccctc
    13621 gtgggtgcgc tgaagttcgg cgatcgcctc ggcgcggcgg gcacgggcac ggggatcgga
    13681 gagcgcctcg tcctcgatgt cgaaatcgac ctcggtcagg tcgtaatggt cgatcactga
    13741 gccgtaggcg gcgatgagtt ggggcactcg ggtgcatgcc gtcgccagtt ccgttccgtc
    13801 ggcaccgccg aaggagaccc gaacgtcgcc acccgcccgg cgggtggcgg cgatacggtc
    13861 cctcaccctg ggctcggcca cgggaacgtc tgcgtcccat tccggcttgc aacggccgtc
    13921 gtcggccacg atgaaggaga ggatcaggtc cttgacgcct ggcggcgtgg gggcggtcgc
    13981 ccaggcattg acgtacggag cgaaccgggg gcccgcgccg gaggcgggcg ggacctgatc
    14041 tgttcggtgc tcggtcttga gtaccgaggg cagcgcgagc gccgacagcc cggccaggac
    14101 cacgaacacc agcacggcag gcacagcgaa cagcccgatg gagatatgtc ccggtgcaag
    14161 ggagccggcg tgtccgcggc agcggaagaa acccctcaca ggtcgctcct ctgttccggt
    14221 cgggaggttg ggaaggaacg ggacggcctg gcctgtcagt tggctgtcct cgaggagaag
    14281 tctcacgctg ccgagtgtgt cgaccctgat gacacgctga taagcaccac tgtgtcacga
    14341 ttagtaatgt tctcgtctag cctctgcgtc atggatctcc agctcggcac ggccgagtgc
    14401 gcgcccacgc tgagcctcca gcgggaacca tgccaacaag gcaggcaaca accacagccc
    14461 gaacagccct gcggcagacc tgtgttcgtg gaccccaccg gccgccgtgc ccgcctgatc
    14521 gggtgctgcg ccgtggtcgc cgggacggcg ctggtcggct acgcggcaat tttctgcgta
    14581 gggctctcgg gcggcacccc gttcgctcca cggacgctcg tccccggcac cgccggcgac
    14641 gcggatacca caggtgctgt gggcagccgt gccacgtcca gcgcccagcc cccgtccccg
    14701 accgccagga ccgcccggac ctcctgggac ggggcaggca tgctgaggcc cgagccgcga
    14761 tgacgagccg acggccgcgc cgggcgctcg gcgcatcccg gaggctgctg aaggccgtgg
    14821 ccggctgcct tcccgtcgtc aaaggcatcg cgcacccccg cgcggtgctg gctctggccg
    14881 cgctgctcgc gctggcctgc gccatgctgc tcaacggcta tctgcgcgcg gagatcgggg
    14941 ccgacccgcc cggccgggga accagcgact cccgtggggc ggtccccggg agtacgttcc
    15001 ccgtctttca cagggccgtc cccaggggag cggtctccgt gggcacgccc cccaggagcc
    15061 gagccttcga tgcggcgcgt ctcagggccg ccacagcgag gaggggctcc taccagcgga
    15121 cggtccccga agaagtgctc accggaggcc cggtcctcac cttcgctgcc gacggcaagg
    15181 tgaccagcca ccgcatcccc cgcaatacca tcgcactgac cttcgacgac ggaccggatc
    15241 cggagtggac cccgaaggtg ttggaggtcc tgcggaagca cgacgtgtct ggaacgttct
    15301 tcgtggtcgg ccggatggca gcccggcatc cccaactgat ccgccggatt ctggagtccg
    15361 gcaacgagat cggcgtgcac acgttctcgc accccgacct gggatcccac agcaccgggc
    15421 gtatcgaccg cgaactcgcg cggacacagc tggtgctggc cggcgcagcc ggggtcacca
    15481 gctcgctctt ccgggccccg tacacctcct acgtcacggt gctcgacgac cgcgactggg
    15541 cggtcacccg gtatctcgga cgcaaggggt acatcagcac gttcatcgac aaggacagcg
    15601 aggactggcg gcagctcgcg gccgcgaaaa tcgtgcgcaa cgccatgccg aaggccggcg
    15661 cgggcgcgtc cgtactcttc cacgacgcgg ggggcgaccg cgcacagact gtccgcgccc
    15721 tcggcatgta catcaaggag atgaagcgta ggggttacgt gttcaccacc gtcaccgggg
    15781 ctctctcagc ccccagcgct gtgcacaagg ccgggacggt gcgtctgtgg gaaggcaggg
    15841 ccatggtcgc cgcggtgtcg ctgaccggcg cggtgatgcc ggcgttgaac gtcctgctgc
    15901 ttgccgtggg cgcggcggtc atcgcccggt tcatcacgat gcccgtcctt gcggcgtggc
    15961 accaccgctc acgcaacagg cggtcctgga cctgggggcc gccggtcacg gagcccgtga
    16021 gtgtgatcgt cccggcgtac aacgagaagg agtgcatcgc ccatacgatc acttcgctgg
    16081 ccgcgagccg ccaccccatc gagatcatcg tcgtggacga cggctccacg gacggcaccg
    16141 ccgacatcgc cgaggccatg aagctgccct ccgtacgcgt gatccggcag cgcaacgccg
    16201 gcaagcccgc ggccctcaac cgcggtgtgg cgaacgcccg gcacgacctg atcgtcatga
    16261 tggatggcga cacggttttc gagcccggca ccgtcggcga gctggtccgc ccgttcgccg
    16321 acacccgtgt gggcgcggtg gcggggaacg ccaaggtcgg caaccggaat tcggtgatct
    16381 gcgcctggca acacatcgag tacgtcatgg gcttcaacct ggaccgccgg atgtacgacc
    16441 tgttgcgctg catgcccacc atccccggcg ccatcggggc cttccgtcgc acggcgctgg
    16501 tcgacgcggg cggcatgagc gaagacaccc tcgccgagga caccgacatc accatcgccc
    16561 tgcatcgcgc gggctggcga atcgtctatg ccgaacatgc ccgtgcctgg acggaagtcc
    16621 caaacagcgt aggccagttg tggcgccagc gctatcgctg gtcctacggc accatgcagg
    16681 ccctctggaa acaccgccgc tcggtcgtcg accgcggatc gtcaggacgc ttcggccggg
    16741 tcggcatgcc gctggtggtc ctcttccaga tcctcatgcc tctcttcgcc ccgctgatcg
    16801 acctgttcat gctctacggg atcttcttct tcgaccccgt gaggtcgctg gcggcctggg
    16861 catcggtcct gctcgtgcag ttgctgtgcg cactgtacgc gttcaagctc gacggcgagc
    16921 gataccgctg tctgttcctg ctgcccctgc agcagatcgt ctaccgacag ctgatgtatc
    16981 ttgtcctgct gcactcctgt gccacagcgg tcaccggcgc ccgccttccc tggcagaaac
    17041 tgcggcgcac cggcgaggtc gacgcgccgc cccggccgcg tgtcgtgacg gggcaggttc
    17101 ctggcaacgg ctgatgcggg cccgggcgca gctcctcacg aggggaggac tgcgcgtcct
    17161 cccctcgccc aggtcccccg accgggaaac agcgtggccg ccgcgatcaa catgagcatg
    17221 ccgcgtcggt cgagggtcgt gcggcgggcc atgtccgacg acaccacccc agttcctggt
    17281 caacgaggcc cagcagcaga aggacgagga ggcacgcgag gccttccacc gcgactcgcc
    17341 cgtcgccccg accctgcgcc acatccagcg gtcgatcgag ttcatcgaac tggtcggcgt
    17401 cttccatgct ctggtcacag ccgccggcgg atcgtcttgc ggctgagggg caggcatctg
    17461 tcggacgacg aacgcgctgc agagtgcctg agcttgactc tgagcgtcga tcggggatcg
    17521 ggtcagaccc tcgagcggtg cctcccacat cctcacagtc ggggatcttg gagtttcccg
    17581 gtgcaatgac atgaccaacg ggcatgctcg gggctgttcc gcgggcggat gcagttgatg
    17641 gggtgtccgt tgtccctctg ttcccgttcc ggtgagcaag tcccttgtct gaccgcgcag
    17701 atcgcgcggg cgagcgatgc gggcgctacg acggcgatat gggtgcggga ccggcggtct
    17761 ctgcggcgcc ccgcgtgcgg ggctggggag ggcgcggggc gccgcggtcg aaccggtgcg
    17821 ccgggcaggt cagggatgcc tggcgcaccg gtgattcgaa gacgcccccg ccgtgccggg
    17881 cggatgcgtg gttggggcgc accgtgccgg tgtgctcggt gcgggtggcg cgtcgccgtg
    17941 gatgaaggac ctgtccacct cggtggtcgc gctgctggtg tccgaggcgt gcaacatcgg
    18001 cctggccccg gtggtgaacc ccgcccatga ggcgctgacc cgggcccggc tcgtgcacgt
    18061 cgaccagtcc tacctgcggg ccgacacggt cgccgcagcg aacgcgcggc tgatggccgc
    18121 ccaggccgag gtgcccatcg tgaagttctg gggcgagggc ctgctcgcct cggtcgacgg
    18181 actgcggttc gtcgtccccg tccggaccgt cagcgcggcg ccgtcgccga agtacttcgg
    18241 gctcaagcgg ggcatcacct ggctcaacgc agtaaacgac caggtcgcgg gcatcgggca
    18301 gatggtcgtc cccggcaccc cgcgcgactc cctgcacatc ctggaggcgc tgctgaacct
    18361 ggacggcggg gtcaagccgg agatggtggc gaccgacaac gcctcgtact ccgacatggt
    18421 gttcggcctg ttcaagatcc tcggctacaa cttcagcccg cggttccgcg acctggacga
    18481 ccagcggttc tggcgggcca cgatgcccgg cgtcgagaca ggcacgtacg gcgcggtgga
    18541 ggacctggcg cgcaaccgcg tgaacctgag caaggtgatc acgcactggc cggacatgct
    18601 gaaggtcgcc ggttccctgg tcaccaacca ggtccgtgcc taaccctgct gcgcatgttc
    18661 ggacgagagg ggcgcccgac tccgctgggt gcggcgttcg cggagtacgg gcggatcgcc
    18721 aagaccgagc acctgctgcg catggtcgac ccggtcgacg gcacctaccg gaggcagatg
    18781 aaccggcagc tcaccgtcca ggaatcccgc cacaagctgg cccgggaggt gtgccacggc
    18841 aagcgcggcg ccatccacca ggcgtaccgg gacggcatgg aggaccagct cggctcgctc
    18901 ggcctggtcc tcaacgccac cgtgctctgg acgacccgtt acatcgacgc cgccgtcgcc
    18961 cagctccagg ccgagggcca cgagatccgc gaggaggaca tcacccggct ctccccgctc
    19021 aagcaccgca acctgaacct gctcggccgg tacaacttca ccgcctcggc cccggcggcc
    19081 ggcgccctgc gcccgctgcg cgacccggac gcgcccgagc tcgacgagga cgacgaaagc
    19141 gtggactgaa cgctcacatc gggtgacgcg ggcacatcag gtggccgggg tgctcggaca
    19201 tcgcaagcgc cagttgggga gccgatgtca ggctgcctgg tatgtccaac taagccttga
    19261 ttggtgcggc cgtcctggcg gccagctcga tcttcgcgca gtaggctgca cgggcttcct
    19321 cgtcgatctg cttctcgtgt tcggcgcgca acccggtccg gccgtcgagg ccctcgcgca
    19381 ggatatcggc gtgcccggca tgccggatgg actcgccgag gacatggacc atgacggcga
    19441 acaggttcgt gtcggcataa ggctctggcc accacggcac gtggccgggg gcgtcgaggg
    19501 gaagctcgtt gatcgtcgcg tccgagtgtt cccacgtgcg ccggtagaac ccgatgatct
    19561 gatcgcgggt ctcgtcctcg gtcgcccaca gatcgctgcc gtcggagtcc tgccaccggg
    19621 gcagcggttc cggggaaggg cggtcgaaga cctcgccgaa gtacctggcc tcgacgctgg
    19681 ccacgtgttt gaccaggccg aggaggttgg tcccggtcgc tgtcaaaggt cggcgggcgt
    19741 cgtattcgga caagccgtcg agtttccaga gcagcgcctc gcggtcccgc cgcagtctcc
    19801 cgtgcaggtt gtccttcgcg aattcatcga tcatgcggca tgagcctgcc atgggctgtt
    19861 cgtggtctca agatcccgta catggtccgc aacgactggc agagccgggg cctggccatg
    19921 gccgccgttg ttcacgctca cggacagcac tgcctcgcgg cgaagagcgg gcgccgtcgc
    19981 cggcctctgg cggccgcgag ggcgtagggc cgaacgggtg gcgggaaacg ggcaggctgg
    20041 acaccctcac cagagttcaa ccctgcgacc gaggatcgaa ccctgctcgc ctgtcgtcaa
    20101 acgatcgttt gacgacaggc gagcgatgcg tccaatgaac ccgtgcaatc cgggggttcg
    20161 cggcggcgcg aatccaatct ccaccgcgac caggtggcgc tgcgcatcca cgacggcgcg
    20221 ttctccgaat cccgaagtta cgtcagcagg cagtcgagcc gccgccgaag gaagaacccc
    20281 ctggccacag gggcaagcgc tcagcggagc tttggggaac tcgccggatg tcgcacagtc
    20341 gaagatgtag ttgccggtgc gagacatgtc gtccttcttc gttgtggtgc tgtgccggcg
    20401 ggcagggttc aggggttgat gaggaccttg agggtgttgc ggtcggccat gtcctggtag
    20461 ccgaccggga ctccatcgag agcggtggtg gcgtcgaaga ccttcccggg ctcgatcgtg
    20521 ccgttgagga tgtcgggcat cagttcctcg atgtaggcac gtacgggggc ggggcctcca
    20581 gcgaggcgga tgttgtggcc gaagaggctg ccgaagccga cggggtcgtc ctcgcactgg
    20641 gggacgccga cgcggctgat gacgccgccg tggcgcacga tgccgaggga ctgttcgtag
    20701 gcgggcgtgt tgccgacgca ttcgaggacc acgtgcgtgc cgtcgccgcc ggtgagttcc
    20761 cgtgcctgct cgatgccttc ctcgcctcgg gcggagacga cgtcggtggc gccgaactcg
    20821 cggccgaggt cggtacgcgc atggtggcgg cccatgagga tgatctgttc ggcgcccagg
    20881 cgcttggccg agagcacggc catcaggccg acggcgccgt caccgatcac ggtgacgcgg
    20941 gtgcgctcgt tcacgccgcc cgcgacggcg gcgtggtaat cggtgccgag gacgtccgtg
    21001 agcgtcagca gggacgggat gaaggcggag tccggggcga cggggagctt gacgagggtg
    21061 ccgtcggcga gcgggacgcg gaccgcttcg gcctggccgc cctcctccgg ctcgccgccc
    21121 cagaagttcg cctgcgggtg ggcgcaggag gtgtgcagac cctcgcggca gaaacgggca
    21181 ggtgttgtcg gagacggcga acggggcgac gaccaggtcg ccgcgcttga cggtggtcac
    21241 ctccgagccg gtgtcctcaa cgacgccgat gaactcgtgg cccatccggg ccggcccgtc
    21301 ctcgggcttc atcgagccgt agggccacag gtcgctgccg cagatgcagg agctggtgat
    21361 gcggaccagc gcgtcggtgg gcagcttgat gatggagtcg gggacgttct cgacgcggac
    21421 gtcgccggcg ccgtacatga gggtcgcgcg cgtgaatgct ctccagtgcg gtggtgcggg
    21481 ttcgagggaa agcgactggt cagggggtag ggctgggccg gctc
//
