LOCUS       NZ_CP022161            49396 bp    DNA     linear   CON 15-DEC-2024
DEFINITION  Streptomyces capitiformicae strain 1H-SSA4 chromosome.
ACCESSION   NZ_CP022161
VERSION     NZ_CP022161.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces capitiformicae
  ORGANISM  Streptomyces capitiformicae
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10989391)
  AUTHORS   Liu,C.
  TITLE     Streptomyces capitiformicae sp. nov., a novel actinomycete producing
            naphthoquinone compounds isolated from the head of Camponotus
            japonicus Mayr
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10989391)
  AUTHORS   Liu,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2017) Life of Science, Northeast Agricultural
            University, No. 59 Mucai Street, Harbin 150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. Feb-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002214185.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 14:26:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,013
            CDSs (total)                      :: 9,935
            Genes (coding)                    :: 9,274
            CDSs (with protein)               :: 9,274
            Genes (RNA)                       :: 78
            rRNAs                             :: 2 (5S)
            complete rRNAs                    :: 2 (5S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 661
            CDSs (without protein)            :: 661
            Pseudo Genes (ambiguous residues) :: 0 of 661
            Pseudo Genes (frameshifted)       :: 220 of 661
            Pseudo Genes (incomplete)         :: 571 of 661
            Pseudo Genes (internal stop)      :: 32 of 661
            Pseudo Genes (multiple problems)  :: 155 of 661
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:06:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7529663
            Orig. end                         :: 7579059
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022161.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..49396
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="NRPS-like"
                     /product="butyrolactone"
                     /region_number="32"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..49396
                     /SMILES="NC(CCCNC(N)=N)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /detection_rules="AfsA"
                     /kind="neighbouring"
                     /product="NRPS-like"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..42955
                     /SMILES="NC(CCCNC(N)=N)C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..42955
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:22955](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..22955)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     gene            320..1096
                     /locus_tag="CES90_RS33730"
     CDS             320..1096
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CES90_RS33730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_189787337.1"
                     /transl_table=11
                     /translation="MAASGGGSGLFSMAWGIWATGFGWIIASDFRGAAHRFYELSQRSV
                     PFSARRAPLVGVGFLRILAGVFALIGPAVLVGGLLELVRGEGASDRLPQLPVPLAATVV
                     LVGAFGLWTAWRPSGLLRREWAEGADLQRAAVAVVTAALVGFPATLALGHQTAMLASWL
                     GGGLAGLVLLLSGRFIFAEQVQAEGFARLPGLRDLVLDPAGTTLRGQLTGELDALVKAA
                     ARHHVTALRVTEPALDDLFHAYYTDAEAAPCPTAAV"
     misc_feature    1528..1542
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     gene            1665..1805
                     /locus_tag="CES90_RS50195"
     CDS             1665..1805
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CES90_RS50195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_229914341.1"
                     /transl_table=11
                     /translation="MLLNSVGLEFMKMAWADETATGLICWRCGFVHLFVNKDIKLYRAD
                     K"
     misc_feature    1987..2000
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.42"
                     /tool="antismash"
     gene            2411..2779
                     /locus_tag="CES90_RS33740"
     CDS             2411..2779
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986498.1"
                     /locus_tag="CES90_RS33740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_189787339.1"
                     /transl_table=11
                     /translation="MSAIQSALRRAMSVEGVLGAAIVDYVSRMPLGTIGNPAGLDLEEA
                     AQRDTDVVRVNLSALAQLGYEPRRVEDILITLDTEYHLLRPLARRAHDGLFIYLVLDRD
                     LADLDTARKELLRIEELL"
     gene            2776..3696
                     /locus_tag="CES90_RS33745"
     CDS             2776..3696
                     /NRPS_PKS="Domain: Abhydrolase_1 (34-277). E-value:
                     1.9e-16. Score: 52.4. Matches aSDomain:
                     nrpspksdomains_CES90_RS33745_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019075759.1"
                     /locus_tag="CES90_RS33745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_229914342.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2e-09, bitscore:
                     37.6, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 3.6e-11, bitscore: 42.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRATPGMGLDEHPTQIAELADGPVEYRFDRRGPDTVVVFHGGHMR
                     AGLSLGEEVFADAGCSVLVPSRPGYGRTPVSTGGSAGGFADVTAALCSQLGIASVAAVV
                     GVSAGGPTAVAMAARYPALVDRMILQSAVGPLPWPDRRTRMAARVAFTARTEPLLWAVV
                     RTLMRHAPEVGLRMLLRDLTVLPSRKAVSGLGAEDRARLIALFSRMRSGHGFLRDLKAL
                     ETTAELTRHAGQVSQPSLVIATCQDGAVPFAHARALVAALRQTELIESWAGGHFIWFGQ
                     DWPTIADRIRDFLLADLYLMPRGEL"
     aSDomain        2878..3606
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CES90_RS33745_Abhydrolase_1.1"
                     /evalue="1.90E-16"
                     /label="CES90_RS33745_Abhydrolase_1.1"
                     /locus_tag="CES90_RS33745"
                     /protein_end="277"
                     /protein_start="34"
                     /score="52.4"
                     /tool="antismash"
                     /translation="TVVVFHGGHMRAGLSLGEEVFADAGCSVLVPSRPGYGRTPVSTGG
                     SAGGFADVTAALCSQLGIASVAAVVGVSAGGPTAVAMAARYPALVDRMILQSAVGPLPW
                     PDRRTRMAARVAFTARTEPLLWAVVRTLMRHAPEVGLRMLLRDLTVLPSRKAVSGLGAE
                     DRARLIALFSRMRSGHGFLRDLKALETTAELTRHAGQVSQPSLVIATCQDGAVPFAHAR
                     ALVAALRQTELIESWAGGHFI"
     misc_feature    3796..3811
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.81"
                     /tool="antismash"
     gene            3974..4969
                     /locus_tag="CES90_RS33750"
                     /pseudo=""
     CDS             3974..4969
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536894.1"
                     /locus_tag="CES90_RS33750"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MMAAVTAVDLAASPGVGFLPLLSLGPAFASLVGG"
     gene            <5034..5308
                     /locus_tag="CES90_RS52105"
                     /pseudo=""
     CDS             <5034..5308
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433420.1"
                     /locus_tag="CES90_RS52105"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="alpha/beta hydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="VPWAAADPRITAAVFGLHWPDALAETAKQIAIPIEFMLQRDDEHI
                     PRQSGLALFDASPRRRRRCTPTRARTRTCPGPRPQHCGVGQGFSAA"
     gene            complement(5305..6765)
                     /locus_tag="CES90_RS33755"
     CDS             complement(5305..6765)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996003.1"
                     /locus_tag="CES90_RS33755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SulP family inorganic anion transporter"
                     /protein_id="WP_189787340.1"
                     /transl_table=11
                     /translation="MFQRVAKETLSGLTVAIVALPLAIAFGITATGTSEGALIGLYGAI
                     FAGFFAALFGGTPAQVTGPTGPITVVATGVIATHGLEAAFLAFIMAGAFQILFGLCRLG
                     SLIRYIPHPVVSGFMGGIALIIILGELDQVQKSFLVVAGTIVLMLVSTRVIKSIPASLI
                     ALVVMTVALRLVDSLLQDVRVGPVSLNTAIDYIGKIPESIPSITLPEFSGSLILTLVLP
                     ALSIALLGSIDSLLTSVVMDNITGNRHHSNKELIGQGLGNAASGLFGGLASAGATVRSV
                     INVRSGGRTALSAATHSVILLALVVGLGAVVQYIPLAVLSGILILTAFGMFDWESLRKA
                     HVSPRGDVAVMFATMIITVVVDLTVAVAVGVVLALIVHAVKSRRHKASIVHDGTGTYHI
                     EGPLSFLSIDRVFTTLRNNRSNLSLNLKHVDYIDMSGAKALLTFIDHSHKSGVELGVKD
                     LPLHVENRLIALADEEQRDKLMTVVENR"
     gene            7304..7963
                     /locus_tag="CES90_RS33760"
     CDS             7304..7963
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010356058.1"
                     /locus_tag="CES90_RS33760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1707 domain-containing protein"
                     /protein_id="WP_189787379.1"
                     /transl_table=11
                     /translation="MSGEISPTGKHSGPSSSPGLRASHADRDRVVDVLRIAAGDGLLTA
                     DELDERLEAALSARTVSELTALTADLPPVSATAGATVPEVKDVVRIEQVHSGAVERVGR
                     WVVPRRLELAVTYCEVTLDFTDAVITHDTLRIDVAMTGKTLTLVTRPGIVVDTDGLQLV
                     HSRVKYRQTPTNPDTPVTLRVELVGQKVYGRVVVRPRRRTLGQWLLRRPTSRSAGA"
     gene            complement(<8385..8561)
                     /locus_tag="CES90_RS50205"
                     /pseudo=""
     CDS             complement(<8385..8561)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013396.5"
                     /locus_tag="CES90_RS50205"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSVTTIVSVIGGRLADVLDLEVQITEPAVFDSREAVFDSREAIPG
                     SLFLALKGEQADGH"
     misc_feature    8540..8554
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.18"
                     /tool="antismash"
     gene            complement(8586..9554)
                     /locus_tag="CES90_RS52110"
     CDS             complement(8586..9554)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010640213.1"
                     /locus_tag="CES90_RS52110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase family protein"
                     /protein_id="WP_373313584.1"
                     /transl_table=11
                     /translation="MRWLRVTQFQRLLKVVRERGGNGTLRGRPWSLPLTERVLVVAVYY
                     RTNLTMRQLGPLFGVSSSAVCRIIQRLGPLLALEPVDRPDDDPDRLWIVDGTLVPVRDR
                     SVGASSRSYRFSANVQVIVDTDTRLVVAAAGAPTQKIYARWCRHMCGITCLRMVLLHRD
                     GHAPSMFELLNGACRYGAYVKQDDGTIKGLIYAPFVEYVADTHRLPGEVHGELDLDGLV
                     DLLGAGRMVMVSVSKEIRRPDIAPERRGGHLVLAIGRRDGQIILRNPSGHTPEALAPTM
                     PLDRFGAFFGGRCLSLDPRSTVRRRTALTAASRPGASQPST"
     misc_feature    complement(9516..9518)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9921..9936
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 24.53"
                     /tool="antismash"
     misc_feature    complement(9921..9937)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: strong, score: 31.35"
                     /tool="antismash"
     misc_feature    complement(9922..9937)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: strong, score: 31.91"
                     /tool="antismash"
     gene            <9994..10343
                     /locus_tag="CES90_RS50210"
                     /pseudo=""
     CDS             <9994..10343
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011027540.1"
                     /locus_tag="CES90_RS50210"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="EDLTFEVSKHGKPVTDLQPYLGAYGHLVALRAGDLAYLHVHPNDE
                     AGTKPRPTISFTATATPTATATARTPTASSSTSSTAAQCTPRVSPFRRASEPPPKAMTT
                     RRTAARRSTTTG"
     gene            complement(10437..11825)
                     /locus_tag="CES90_RS33785"
     CDS             complement(10437..11825)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018837223.1"
                     /locus_tag="CES90_RS33785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_189787343.1"
                     /transl_table=11
                     /translation="MSETRTADTYAPGAPHPLRWLALGLLGLAQLMLILDLTVVAIALP
                     HMEADLDLGRAAVTWVVSGYALTFGSLMLLGGRATDLFGAKGVALAGLTVFTVASLTAG
                     LATSAPMLLTSRVAQGVGAAMLSPAALSVVVRLFDGDERNRALGVWSALGGGGAALGVL
                     LGGVITAGPGWTWVFFINVPVGLVILVALIRILPDLPKVASGSLDVPGAALVAAATGAL
                     IYALIRAGDHGWLNGVSLALLAVSVVLYAAFAAWQRRASAPLMDLGLVGRRPVVAGTFV
                     ITVTTALMVAVFFLGSFYLQNQENHGALAAGLLFLPVALLTMACATVAGRLIGRLGARA
                     MAAVALVIAAAGFLMPVFWAGTVAMVAGVSVSSAGLGALFVVASATALSSVAPHEAGVT
                     SGVVSTFHEFGAAAGAAAVSSAAAASIAGSSSASGFDDAFLVAMGVAAVSALVSMWLIP
                     PKGE"
     gene            11929..12537
                     /locus_tag="CES90_RS33790"
     CDS             11929..12537
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557405.1"
                     /locus_tag="CES90_RS33790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_189787344.1"
                     /transl_table=11
                     /translation="MSTRSTAKRADALRSIDAIVQAATECLGHNPDASLSEIASAAGVG
                     RVTLYSHFASRAEVVDAALTRAIDQGNAALDAVDLTGDPQLALARLVDESWHLVDQARA
                     LLVAAQRELPPGRIRELHNGPAARVETLITRGRAEGAFRTDLPIPWLITVLHSIMKGAA
                     DEVRTGNLTPDRAAAHITATVLAAFTPPGKQVPEPDGER"
     gene            complement(12752..13312)
                     /locus_tag="CES90_RS33795"
     CDS             complement(12752..13312)
                     /EC_number="1.-.-.-"
                     /EC_number="1.4.3.5"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016641170.1"
                     /locus_tag="CES90_RS33795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_189787345.1"
                     /transl_table=11
                     /translation="MAIEASLTDRTARLLNEARYLNLATTWDGTPWVATLEYVWFPGPL
                     RLVFGSTTGSRHSRDIDREPRVSGSLFVTAGAAGVAIAPVDGAQFTGLCSEIGPDLLEE
                     YYTPFYETVFPDAEQRAQWQLPRELLRPPAAHRLYVVTVERWWLIDTRTWADDRIDRRI
                     ELPLDATTQTRLSTRPSSNPLTR"
     gene            complement(13377..14606)
                     /locus_tag="CES90_RS33800"
     CDS             complement(13377..14606)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325308.1"
                     /locus_tag="CES90_RS33800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_229914343.1"
                     /sec_met_domain="p450 (E-value: 3.5e-19, bitscore: 68.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHFSAVPTETIESTGGRCMYAQVERLRASGPAVAVQLPEGVGAW
                     SVSRGDVVRRLLTHPGVSRDLKKTVPSYQPGSVPWLSPWVDLDSMATTDGREHTRLRKL
                     ITPAFSPRRVEMLRPHIEADVAMLLDALAAHPGDEPVDLHQEFSYCVPTQVICDLFGIP
                     DDQRPEVLRVFRAVARTDLTEEESIALYHDLEAAMHLLIGTKRRTPGEDLTSFLINARE
                     EGEESLDEHELVSTLLLMIGGGSQTTINLLDHTIRELLVRPDQLALLKADPARWDDAIE
                     ESLRVHCPVMHLPMRWAAEDIDLGEGVVIRAGDAILICYGAHGRDPQVHDDPATFDIDR
                     EDKEHLAFGLGPHFCPGSRLARLEARIALPALFDRFPRLTLAVEPEDVPPGPTFIGNDI
                     AALPVFLRHR"
     gene            complement(14757..15410)
                     /locus_tag="CES90_RS33805"
     CDS             complement(14757..15410)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015057.5"
                     /locus_tag="CES90_RS33805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_189787346.1"
                     /transl_table=11
                     /translation="MTDVVAAARQQIAGQAGPNGFVDALEHGRVPKERLGWLAGELHHL
                     VSSDRRSFALLASRFPSAPAGDLYLAMAEGEAQALRLLMEFAAALNLEERDVRAYEPQP
                     LAQAYPAYLTQSALYGASSDVALALLANVRESGATYTRVAEALASQYGFEERALGHFLF
                     FADTPQTLLDQATATLEEGLAGGDDPAAAVRCARTVHALEEAFWSCLARGLDDG"
     gene            complement(15416..17281)
                     /locus_tag="CES90_RS33810"
     CDS             complement(15416..17281)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541499.1"
                     /locus_tag="CES90_RS33810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_189787347.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 4.8e-19, bitscore:
                     68.3, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 5.7e-19, bitscore:
                     67.3, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.8e-26, bitscore:
                     91.3, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAREAPEHPSGHDTTPPLRRPGYAAGLFLGQVNTDLLALPEGDP
                     RRLDPAEERFLSRLREFCEKEVDSAGIERADRIPDHVIEGLKDIGAMSIKVPRQYGGLG
                     LSSRCYHRALMLTSTTHPALSELLAGHQAIGLAQPIALFGTEEQKRQFLPRCVREISAF
                     ALTEADIGNDPFRMHTKAVHDPASDSYVLDGVKTWTTNAVVADLLVVMALVPASENGAG
                     GMTAFVVEADTPGVTVEHRSAFLGLRGLENGSVRLHQVVVPARNRIGAEGEGLTIALAA
                     QDTGRLSLPAVCAAAAKWSLSTARQWSAARVQWGRPIGQHDAVAGKLSFIAATAFALEA
                     MVEVIGRQAEQGDTDARLDAELAKLFATEQAWVVADELVQIRGGRGYETAESAAGRGER
                     GIPVEQLLRDVRIGRIFDGSSEALRGFLAHDLIAAHRSSAGQREAVPTGRRARGDGSVL
                     DTHLAFVEQTSRRLARELAAIAEGPTTEIDERQRFLGRIVDIGAELYAMSASCVYAEAL
                     DAVGASAARLADAFCRQARLRIVHLFDRLADNTDEQDRGLAHSVLGGDHTWLEDGVVDP
                     STDGPWIAEPEPGPAKVPSLRRVLRAADSLTATPSMSDGPTRRAQ"
     gene            complement(17278..18339)
                     /locus_tag="CES90_RS33815"
     CDS             complement(17278..18339)
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013087.5"
                     /locus_tag="CES90_RS33815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase"
                     /protein_id="WP_189787348.1"
                     /transl_table=11
                     /translation="MSSTASPDVLATEKMNLRAALIERIGGYMTAHAIGVAAELGLADL
                     IGSGSRTSEELAAETQTHEPSLRRLLRTLVAVGIAAEPEPGRFTLTDIGAQLRSDSPDS
                     LHKFARMFCHPIFFTSWQSLHHAVTTGERAFNHAYGTGIYDWLAQHEETSTLFNEAMSE
                     ESRISAGQLAAAYAFPAAGTVVDIGGGDGTLLTAILLARPGLRGIVFDSPSGVAEAPAA
                     LSKAGLTDRCAVQAGDFFQSVPGDGDLYIIKSVFQDWGDEEARAILRTCRAHMPDSATL
                     LIVGTVLPETADTSAPVAFFTDINMMVMAGGRERTESEFRALLEETGFTVRSVGLGQAG
                     PLSVIEAVPTAAA"
     gene            complement(18397..19164)
                     /locus_tag="CES90_RS33820"
     CDS             complement(18397..19164)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003959273.1"
                     /locus_tag="CES90_RS33820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetyltransferase"
                     /protein_id="WP_189787349.1"
                     /transl_table=11
                     /translation="MSSTTASHDLRVISIAGRPDLAEAMLTMESSWPAYIRPDPLLVDW
                     AFDRHAEHQLVLVDEDDRVVARAASVPLAWDGDPGRLPDTGWDEALRQSLSDTYAGRAL
                     TTLCALEVAVIPGYQARNLSGHTLRALFDHARGKGFRNLVVPVRPNGKHRRPELPLAEY
                     VALRRPDGLPEDPWLRVHARAGGEVLQVCPASMTISGSLAQWREWTGLPLDVDGPVEVP
                     GALTPVTVSVEHDYAVYVEPNVWVRHRFTAPRP"
     gene            complement(19208..19993)
                     /locus_tag="CES90_RS33825"
     CDS             complement(19208..19993)
                     /EC_number="2.3.2.6"
                     /GO_function="GO:0008914 - leucyl-tRNA--protein transferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0030163 - protein catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313071.1"
                     /locus_tag="CES90_RS33825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="leucyl/phenylalanyl-tRNA--protein transferase"
                     /protein_id="WP_208921477.1"
                     /transl_table=11
                     /translation="MYIRTQARPETPWESLNVLAAPTEGPAAFGGDLGPRSLLTAYRHG
                     LYPFPAETAEHCIVNELTYEADVAAGRVKLIPGYDDPFSIAWCSPDPRPVILVQQARIQ
                     RSLRRQLRKETGWTTTADVCFERVARQCRAGRTERWLTDDLLRGLCLLHELGHAHSVEV
                     WDGDELIGGVLGVRVGAVFSADSQFTLRSGAGKAAVADLTRRFAEAGGLAVDVQRDGDH
                     VRLLGAQPMSRRQYFGLLSARDEGRPLATGRLPARRLAD"
     gene            complement(20001..22955)
                     /locus_tag="CES90_RS33830"
     CDS             complement(20001..22955)
                     /NRPS_PKS="Domain: AMP-binding (3-387). E-value: 2.4e-91.
                     Score: 298.3. Matches aSDomain:
                     nrpspksdomains_CES90_RS33830_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (498-571). E-value: 1.1e-13. Score:
                     43.2. Matches aSDomain: nrpspksdomains_CES90_RS33830_PCP.1"
                     /NRPS_PKS="Domain: TD (612-855). E-value: 1.4e-82. Score:
                     268.5. Matches aSDomain: nrpspksdomains_CES90_RS33830_TD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325301.1"
                     /locus_tag="CES90_RS33830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_229914349.1"
                     /sec_met_domain="AMP-binding (E-value: 3.9e-106, bitscore:
                     354.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4e-07, bitscore:
                     29.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 4e-60, bitscore:
                     202.2, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHDGHRISYAELDKRADRLAHRLRALGAGRESVIMVHLERSIDL
                     IVSFLATLKAGAAYLPVEPGIPDDRLSAYVKGTDCALVITRSDHEHRFAALPVRPLRAD
                     ADLAAGSPVDPPPVAVEASDTAYVIYTSGSSGSPKAVKVGHASLGYLFRHVSERYGIGP
                     KDRVLQFAALSFDTSIEQILVTLLNGATLVLPEYNWAPSELPGRLTALGVTVMDLTPPY
                     WRAFLAELARNPVELPVRLTIVGGSAVHAEDCRTALRLLPGSRLVNAYGLTETTITSCT
                     MDITPEVLPAQGPAPVGQPLPHTVVHVLDQDLKPVPPGRHGEIYIGGPGVAQGYLAGMA
                     PGEKRFLTLPGSTADSARVYRTGDLGGWTAEGNLEVVGRADRQLKVRGFRVEPAEIEAA
                     LSAHEFIDDVAVTAFSHRGEPLIAAYFTANRAPHRLDPGELRAFAAHHLPAYMVPARFV
                     QLDEMPTTTNGKIDLAALPEPQEPGGASPTGDDAPAARLVERAVAGLWCQVLGIDSVAP
                     GDNFFDRGGNSILAAELLAKVRASLGILITQVRPLIRILLDDATLRGFASAVEAARAGT
                     LSTDTATHAALRADTAVGVPIQSSPTPPTAWADPAHVFLTGATGFLGIHLLHRLLTTTE
                     ATVHCLVRADDAHQARERIRDNARHYLDDGLDAYHASGRIRAVPGDLARPLLGLSEEEF
                     DHLAEVVDVIHHPGGLVNFIYPYSHMRPANVEGTREIIRMAGRYRNIPVHYVSTMAVIS
                     GFGTAGVRHITEETPLAHSDRLSVGYVESKWVAEELLRNAAKEGLPVTIYRAADISGDR
                     ARGAWNTATEMCAMKKFIVDTGTSPIAELPLDYTPVDCYAAALLHIAASRLPSGEVYHL
                     TNPGKVNISLLAERLRAHGHAIREIPWEEWVEGIVSTAIEQPDHPMTPFAPLFIDRCST
                     GEMSVAEMYLETTFPTFSQDNVRAALSGSGIEIPPVDGDLLDRYIRYLTSIDFL"
     aSDomain        complement(20391..21119)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CES90_RS33830_TD.1"
                     /evalue="1.40E-82"
                     /label="CES90_RS33830_TD.1"
                     /locus_tag="CES90_RS33830"
                     /protein_end="855"
                     /protein_start="612"
                     /score="268.5"
                     /tool="antismash"
                     /translation="VFLTGATGFLGIHLLHRLLTTTEATVHCLVRADDAHQARERIRDN
                     ARHYLDDGLDAYHASGRIRAVPGDLARPLLGLSEEEFDHLAEVVDVIHHPGGLVNFIYP
                     YSHMRPANVEGTREIIRMAGRYRNIPVHYVSTMAVISGFGTAGVRHITEETPLAHSDRL
                     SVGYVESKWVAEELLRNAAKEGLPVTIYRAADISGDRARGAWNTATEMCAMKKFIVDTG
                     TSPIAELPLDYTPVDCYAAAL"
     aSModule        complement(20391..22946)
                     /complete
                     /domains="nrpspksdomains_CES90_RS33830_AMP-binding.1"
                     /domains="nrpspksdomains_CES90_RS33830_PCP.1"
                     /domains="nrpspksdomains_CES90_RS33830_TD.1"
                     /final_module
                     /locus_tags="CES90_RS33830"
                     /monomer_pairings="Arg -> Arg"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(21243..21461)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CES90_RS33830_PCP.1"
                     /evalue="1.10E-13"
                     /label="CES90_RS33830_PCP.1"
                     /locus_tag="CES90_RS33830"
                     /protein_end="571"
                     /protein_start="498"
                     /score="43.2"
                     /tool="antismash"
                     /translation="ERAVAGLWCQVLGIDSVAPGDNFFDRGGNSILAAELLAKVRASLG
                     ILITQVRPLIRILLDDATLRGFASAVEA"
     CDS_motif       complement(21765..21827)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CES90_RS33830_0004"
                     /evalue="2.30E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="CES90_RS33830"
                     /protein_end="397"
                     /protein_start="376"
                     /score="32.6"
                     /tool="antismash"
                     /translation="VGRADRQLKVRGFRVEPAEIE"
     aSDomain        complement(21795..22946)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CES90_RS33830_AMP-binding.1"
                     /evalue="2.40E-91"
                     /label="CES90_RS33830_AMP-binding.1"
                     /locus_tag="CES90_RS33830"
                     /protein_end="387"
                     /protein_start="3"
                     /score="298.3"
                     /specificity="substrate consensus: Arg"
                     /tool="antismash"
                     /translation="DGHRISYAELDKRADRLAHRLRALGAGRESVIMVHLERSIDLIVS
                     FLATLKAGAAYLPVEPGIPDDRLSAYVKGTDCALVITRSDHEHRFAALPVRPLRADADL
                     AAGSPVDPPPVAVEASDTAYVIYTSGSSGSPKAVKVGHASLGYLFRHVSERYGIGPKDR
                     VLQFAALSFDTSIEQILVTLLNGATLVLPEYNWAPSELPGRLTALGVTVMDLTPPYWRA
                     FLAELARNPVELPVRLTIVGGSAVHAEDCRTALRLLPGSRLVNAYGLTETTITSCTMDI
                     TPEVLPAQGPAPVGQPLPHTVVHVLDQDLKPVPPGRHGEIYIGGPGVAQGYLAGMAPGE
                     KRFLTLPGSTADSARVYRTGDLGGWTAEGNLEVVGRADRQLKVR"
     CDS_motif       complement(21948..22007)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CES90_RS33830_0003"
                     /evalue="1.70E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="CES90_RS33830"
                     /protein_end="336"
                     /protein_start="316"
                     /score="26.8"
                     /tool="antismash"
                     /translation="PPGRHGEIYIGGPGVAQGYL"
     CDS_motif       complement(22521..22580)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CES90_RS33830_0002"
                     /evalue="2.70E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="CES90_RS33830"
                     /protein_end="145"
                     /protein_start="125"
                     /score="23.0"
                     /tool="antismash"
                     /translation="AYVIYTSGSSGSPKAVKVGH"
     CDS_motif       complement(22770..22808)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CES90_RS33830_0001"
                     /evalue="3.10E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="CES90_RS33830"
                     /protein_end="62"
                     /protein_start="49"
                     /score="14.2"
                     /tool="antismash"
                     /translation="LATLKAGAAYLPV"
     gene            22842..23138
                     /locus_tag="CES90_RS50215"
     CDS             22842..23138
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CES90_RS50215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_229914351.1"
                     /transl_table=11
                     /translation="MDHDHRFASGPESPQAMSQSIRALVEFRVADPVSVVFHRSRIAPV
                     RRHGGEAIMYERLPDDVHKSSRPMRVAKNADRSSAAESGRSRLEGVTDLHVDA"
     gene            complement(23866..24195)
                     /locus_tag="CES90_RS33835"
     CDS             complement(23866..24195)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013756.5"
                     /locus_tag="CES90_RS33835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavin reductase family protein"
                     /protein_id="WP_229914344.1"
                     /transl_table=11
                     /translation="MHKAIKTAGHFGVSIMEAGQEGLVRFFADKTRPLGPGQFADVDWS
                     PGPRTGAPLLSGSLAWLECELSTAYDFGTHSIFIGEVVGASHGGARDGLPFFRGGFRRA
                     VPLSA"
     misc_feature    24320..24334
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.37"
                     /tool="antismash"
     gene            24629..26404
                     /locus_tag="CES90_RS33840"
     CDS             24629..26404
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948354.1"
                     /locus_tag="CES90_RS33840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="biotin carboxylase N-terminal domain-containing
                     protein"
                     /protein_id="WP_189787352.1"
                     /sec_met_domain="ATP-grasp (E-value: 2.6e-08, bitscore:
                     32.8, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKVLIANRGEIAVRVARACRDAGIASVAVYADPDRDALHVRAAD
                     EAFALGGDTPASSYLDIDKVLKAARESGADAIHPGYGFLSENADFAQAVLDAGLIWIGP
                     PPQAIRDLGDKVAARHIAQRAGAPLVAGTPDPVSGAEEVVAFAEQHGLPIAIKAAFGGG
                     GRGLKVARTLEEVPELYDSAVREAVAAFGRGECFVERYLDKPRHVETQCLADQHGNVVV
                     VSTRDCSLQRRHQKLVEEAPAPFLTQEQTAELYRASKAILREAGYVGAGTVEFLVGNDG
                     TVSFLEVNTRLQVEHPVTEEVAGIDLVREMFRIADGDKLGYDDPELRGHSFEFRINGED
                     PGRHFLPAPGTVTTFATPSGPGVRLDAGVESGSVIGPAWDSLLAKLIVTGRTRKEALQR
                     AARALEEFQVEGMATAIPFHRAVVKDAAFAPEVHGQDGPFTVHTRWIETEFVNEIKPFA
                     APADATEAEEESGRETVVVEVSGKRLEVSLPASLGMSLARTGLAAGAKPKRRAAKKSGP
                     VASGDTLASPMQGTIVKVAVEEGQEVKEGDLVVVLEAMKMEQPLNAHKAGVIKGLTAEV
                     GASLTSGAAICEIKD"
     misc_feature    24659..24670
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.68"
                     /tool="antismash"
     misc_feature    26500..26514
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.29"
                     /tool="antismash"
     gene            26502..>27739
                     /locus_tag="CES90_RS52115"
                     /pseudo=""
     CDS             26502..>27739
                     /NRPS_PKS="Domain: AMP-binding (7-187). E-value: 7.3e-47.
                     Score: 151.7. Matches aSDomain:
                     nrpspksdomains_CES90_RS52115_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.5"
                     /locus_tag="CES90_RS52115"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="AMP-binding protein"
                     /pseudo=""
                     /sec_met_domain="AMP-binding (E-value: 1.6e-41, bitscore:
                     141.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLRRVQDGERSWTYRQLHEIAGGLAVALHSVGADPARPVAVLLE
                     RSVWMVAAALAVVRTGSSYVPLDPETPAARLESIVEDAEPAAMITSRSLAGRVPDGVPV
                     VYVDDPLPAAEDFTSAAVGRDTRAYIIFTSGTTGRPKGVQVSHGNLLSLLVASQEVYDF
                     GPNDVWTLFHSFAFDFSVWEGAPPCTAAGWSSYRRRRRRIRRRSGGCCATSGSRSCARP
                     RPPSTTSSRRRPASPTGCHCAG"
     aSDomain        26523..27062
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CES90_RS52115_AMP-binding.1"
                     /evalue="7.30E-47"
                     /label="CES90_RS52115_AMP-binding.1"
                     /locus_tag="CES90_RS52115"
                     /protein_end="187"
                     /protein_start="7"
                     /score="151.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DGERSWTYRQLHEIAGGLAVALHSVGADPARPVAVLLERSVWMVA
                     AALAVVRTGSSYVPLDPETPAARLESIVEDAEPAAMITSRSLAGRVPDGVPVVYVDDPL
                     PAAEDFTSAAVGRDTRAYIIFTSGTTGRPKGVQVSHGNLLSLLVASQEVYDFGPNDVWT
                     LFHSFAFDFSVWEGAPP"
     CDS_motif       26664..26705
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CES90_RS52115_0001"
                     /evalue="3.90E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="CES90_RS52115"
                     /protein_end="68"
                     /protein_start="54"
                     /score="10.9"
                     /tool="antismash"
                     /translation="LAVVRTGSSYVPLD"
     CDS_motif       26883..26942
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CES90_RS52115_0002"
                     /evalue="5.40E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="CES90_RS52115"
                     /protein_end="147"
                     /protein_start="127"
                     /score="34.2"
                     /tool="antismash"
                     /translation="AYIIFTSGTTGRPKGVQVSH"
     gene            27798..29762
                     /locus_tag="CES90_RS33850"
     CDS             27798..29762
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013927.5"
                     /locus_tag="CES90_RS33850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="penicillin acylase family protein"
                     /protein_id="WP_189787354.1"
                     /transl_table=11
                     /translation="MAFGAGVDAAVRRMRRRGGLPVEFLLLRYRPEPWTPRDSIAIVKH
                     LGFDLGRNLANEAFRARLAREHPEYVSAFATPKYPADGAVTIRTALPGKTPARVDTPAP
                     SGLPRASRAWLDALLCGEHPLGSNAWAVSGSRTASGNPLLANDPHIVLTQPSLWYQMGL
                     RLDDEADDAVGYGVTVPGLPGLIAGANRHLAWGITNSTVDTQDLCTLPATDPDEAWTEE
                     SVITVRGAEPVRVRAAGGARHVELDPPGSDGDGRYGLFWSGLVPSAEIEACQRMWRARD
                     YPQLRDALRTFGVPVLNLVVACQDGTIALKTAGNVPAREPGSSGRVPAGHAEVARSWAE
                     FLAFDDLPEVVDPPEGYIVSANHRLLPADAPLDVGVDWLPPYRAERIEELITTDAVVTA
                     AACARWQSDVLDGRARHVLPTLLAALDGQSLETPLAVTCRRLLEEWDGHDHGQMAAPLV
                     FFRLMQVLTEHWIGDRLGQELAAAMPDAALQVDHLMLTPDARAALGDQEELPAAVCRAL
                     TETARRIAAELGEDPSRWRYDRVHRTTDQHPLAKAVPILAPLFGTSSTPVGGSSHTVGL
                     TSSAPSGAVVDGAPWRFVAELSTSGLQLWDVLRHGASGNPISPHYDDQTPAHTEGRHYR
                     VPLLPSPDTAPNLLRLRAR"
     gene            30342..31574
                     /locus_tag="CES90_RS33855"
     CDS             30342..31574
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.5"
                     /locus_tag="CES90_RS33855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_189787355.1"
                     /transl_table=11
                     /translation="MTQQSSSAPGIATVVPTTGPHTARKAGLIAGIILVSLNLRPAITS
                     LGPLLPQIEEDLGLSGTGAGLLTMLPVLCLGVFAGLGPTLRHRFGEDRVLLGCLPVLLG
                     GILLRLLDPTALLYVGTVVVGGAIAVANVVLPSLIKREFPDRVPLMMATYTMALTFGGA
                     AAAGAVIPLQSVVDTDWRGSLGLLAVPVVVGVVAWLPFGLRRVRTRADGRAPIGPLLRN
                     RLAWLVTAFVGLEALLAYVIFGWLPAICVSRGMSEAAAGYMMSAITFLQAAGSMVVPFF
                     IDRGGRGQRGFCVVVALGTAVGLVGIVVAPLWTIWLWALVLGIIGGAAFSLALTLIGLR
                     AGDGDTAAGLSSMSQGVGYALAAAGPFGVGALYQLSGGWGVPLAVLVALCVLMAVIGVG
                     AGRDATLSREM"
     gene            31753..32997
                     /locus_tag="CES90_RS33860"
     CDS             31753..32997
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (38-333). E-value: 4.8e-31.
                     Score: 99.9. Matches aSDomain:
                     nrpspksdomains_CES90_RS33860_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012428.5"
                     /locus_tag="CES90_RS33860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_189787356.1"
                     /sec_met_domain="Aminotran_3 (E-value: 6.9e-36, bitscore:
                     122.9, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVDLPAPEVTDPADPVAVVHRHLIHDGVSAGRRTPVVHRRHGA
                     RIETRDGRVLLDAASGGFGGSHARVRAAIADQARRVALSSRILVSRPLAGAVAALAEFC
                     PGPLSVSYLCNSGDEALDSALKLAKGTHPRRPYVLGIRGEDFGTLSHGQALGQGRALLP
                     GAPFLPRTVSAEAPEELLEQVDESVSAVVIAPAAPGRPLGRLPLDWWVALRERCHRTDT
                     LLVLDERHTGPARLGRDLGVGALGMFPDALILGDTLGADAVPVGVAVLTPAAYRRVYGG
                     RNPSLHGSTFGANPLSAAAVSAVLDAVVGDDLAARQRDFEHAALRLRDELADPAGAFGE
                     LHADGSLLWVRARGAAAARRLAGELADRGVLVRDPVADVVTLTPPLTAEREDIDQILQR
                     LAESLKALDAEEAGR"
     misc_feature    31768..31770
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        31867..32751
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CES90_RS33860_Aminotran_3.1"
                     /evalue="4.80E-31"
                     /label="CES90_RS33860_Aminotran_3.1"
                     /locus_tag="CES90_RS33860"
                     /protein_end="333"
                     /protein_start="38"
                     /score="99.9"
                     /tool="antismash"
                     /translation="VHRRHGARIETRDGRVLLDAASGGFGGSHARVRAAIADQARRVAL
                     SSRILVSRPLAGAVAALAEFCPGPLSVSYLCNSGDEALDSALKLAKGTHPRRPYVLGIR
                     GEDFGTLSHGQALGQGRALLPGAPFLPRTVSAEAPEELLEQVDESVSAVVIAPAAPGRP
                     LGRLPLDWWVALRERCHRTDTLLVLDERHTGPARLGRDLGVGALGMFPDALILGDTLGA
                     DAVPVGVAVLTPAAYRRVYGGRNPSLHGSTFGANPLSAAAVSAVLDAVVGDDLAARQRD
                     FEHAALRLRDELAD"
     gene            32994..34376
                     /locus_tag="CES90_RS33865"
     CDS             32994..34376
                     /NRPS_PKS="Domain: Aminotran_3 (40-362). E-value: 1.3e-67.
                     Score: 220.2. Matches aSDomain:
                     nrpspksdomains_CES90_RS33865_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012428.5"
                     /locus_tag="CES90_RS33865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_189787357.1"
                     /sec_met_domain="Aminotran_3 (E-value: 6.2e-67, bitscore:
                     225.2, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSASTAVAALDRQQVLTTLGRHWNPTAALMLAATGRQLESHARGT
                     EVFGEDGSRALDFAGSYGVFLVGHQNDAVRAAVLDALDTAPSLVPGTVHPATADLFGLL
                     TEILPAGLDRFALGCSGAEISEIALRAAYLARPERRRIVIVEGGYHGKTLGALTVLGQR
                     EHRDDFAPADRDLVIVPPGDAGAVREAVAGRDVAAVFVEPVLGGAYLRVPPADFMPDVA
                     RACRQTGTLLVADEIQTGFGRTGRMFAIEHSGVVPDIMLLSKALTGGFVPVAVVAMSEE
                     VLSDARRSPQWYPGVLDGTGGSALSVAAAAATIRVVRDQNLPERAETVGRALREGLHRA
                     VREHPRHLVDAPGIGLMTGLRTRNPSVENLISMQMAARGIHLGHSLNEQMDQPVLRFYP
                     PLTVSAAEIERVLVALDASLDWLDRRPAWLMRRITWLLRRQYRLPPTLVLKLMHSDLEV
                     NW"
     aSDomain        33114..34079
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CES90_RS33865_Aminotran_3.1"
                     /evalue="1.30E-67"
                     /label="CES90_RS33865_Aminotran_3.1"
                     /locus_tag="CES90_RS33865"
                     /protein_end="362"
                     /protein_start="40"
                     /score="220.2"
                     /tool="antismash"
                     /translation="HARGTEVFGEDGSRALDFAGSYGVFLVGHQNDAVRAAVLDALDTA
                     PSLVPGTVHPATADLFGLLTEILPAGLDRFALGCSGAEISEIALRAAYLARPERRRIVI
                     VEGGYHGKTLGALTVLGQREHRDDFAPADRDLVIVPPGDAGAVREAVAGRDVAAVFVEP
                     VLGGAYLRVPPADFMPDVARACRQTGTLLVADEIQTGFGRTGRMFAIEHSGVVPDIMLL
                     SKALTGGFVPVAVVAMSEEVLSDARRSPQWYPGVLDGTGGSALSVAAAAATIRVVRDQN
                     LPERAETVGRALREGLHRAVREHPRHLVDAPGIGLMTGLRT"
     gene            34382..35020
                     /locus_tag="CES90_RS33870"
     CDS             34382..35020
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023682.5"
                     /locus_tag="CES90_RS33870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thermostable hemolysin"
                     /protein_id="WP_189787358.1"
                     /transl_table=11
                     /translation="MDIAIAESGTPEWYEARIFAQDSYRRTYGATTAPSPDRFVTVRES
                     PRGAIVACAGLSGPGTDGFFSENYLGCPVERALAPVAGDVPERGEVVEVGPLAGAGGAG
                     GELIRLMPVIAWCQGKRFILATVTDRVEEAMARAGVPFVPLRQASADWMDEEARSGWGS
                     YYERSPTTGVVPLDSIGRLINSLTGRYTFVELAVQTLVGTSREVSGAHA"
     gene            35007..36599
                     /locus_tag="CES90_RS33875"
     CDS             35007..36599
                     /NRPS_PKS="Domain: AMP-binding (28-425). E-value: 1.2e-56.
                     Score: 184.0. Matches aSDomain:
                     nrpspksdomains_CES90_RS33875_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606944.1"
                     /locus_tag="CES90_RS33875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AMP-binding protein"
                     /protein_id="WP_189787359.1"
                     /sec_met_domain="AMP-binding (E-value: 2e-56, bitscore:
                     190.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTLEQSLMDLAEDERPLVEVLAPDGSVARSYSYRHVVRAAAELA
                     RTLRERPVRDRGARGAGDPTDPGQLQVGVVTANGPEFLVADFAVLGARGVEVPVPLAFT
                     AEQAAAMLEDIDICLADEAGARRLREWGAEKVLPPGVPLQVLDLERPAASETAAPLFPR
                     AEATARLCKIIHTSGTTSRPKGVCIRESALEELIGSLRAAMPPRAYRRYLSLVPLSLLI
                     EQVTAVYLVVCDAGTVVLLPPEVPLVGTSSFAPQAVLPHVRAARPSALVITPALAEAMA
                     SRAAEARASGRDPVTDLFGRAEAPLVCCGGAPVDADMLRALDDHGIAVHEGYGLSENSS
                     VVSWNTPAARRVGSVGRPLRHVRVRTAPDGELLVKSTSLFAGYKGGDDPSGCDVDEEGW
                     LHTGDLAVIEDGFVWIRGRKKSVIITSAGRNVAPEWVEAQYRSHPAVLAVAVVGDGLPA
                     LHGLFLVDPRVRPEAVRAELDSLGHERLSQVERVEVAHVVPADESLHAEFFTVTGRPRR
                     SAVQAAIAAGRFA"
     aSDomain        35091..36281
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CES90_RS33875_AMP-binding.1"
                     /evalue="1.20E-56"
                     /label="CES90_RS33875_AMP-binding.1"
                     /locus_tag="CES90_RS33875"
                     /protein_end="425"
                     /protein_start="28"
                     /score="184.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ARSYSYRHVVRAAAELARTLRERPVRDRGARGAGDPTDPGQLQVG
                     VVTANGPEFLVADFAVLGARGVEVPVPLAFTAEQAAAMLEDIDICLADEAGARRLREWG
                     AEKVLPPGVPLQVLDLERPAASETAAPLFPRAEATARLCKIIHTSGTTSRPKGVCIRES
                     ALEELIGSLRAAMPPRAYRRYLSLVPLSLLIEQVTAVYLVVCDAGTVVLLPPEVPLVGT
                     SSFAPQAVLPHVRAARPSALVITPALAEAMASRAAEARASGRDPVTDLFGRAEAPLVCC
                     GGAPVDADMLRALDDHGIAVHEGYGLSENSSVVSWNTPAARRVGSVGRPLRHVRVRTAP
                     DGELLVKSTSLFAGYKGGDDPSGCDVDEEGWLHTGDLAVIEDGFVWIRGRKKSVIIT"
     CDS_motif       35523..35570
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CES90_RS33875_0001"
                     /evalue="2.50E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="CES90_RS33875"
                     /protein_end="188"
                     /protein_start="172"
                     /score="17.0"
                     /tool="antismash"
                     /translation="IIHTSGTTSRPKGVCI"
     gene            36685..37602
                     /locus_tag="CES90_RS33880"
     CDS             36685..37602
                     /EC_number="1.14.11.-"
                     /GO_function="GO:0051213 - dioxygenase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: TauD (36-293). E-value: 2.8e-34. Score:
                     111.0. Matches aSDomain:
                     nrpspksdomains_CES90_RS33880_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046: Dioxygenase TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606945.1"
                     /locus_tag="CES90_RS33880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_189787360.1"
                     /sec_met_domain="TauD (E-value: 4.7e-32, bitscore: 111.0,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDLARLTPYGSGTGLLVEPRSADTTLGSLAPEQVVCVLRDAGFL
                     LLRGFRPDLEQFSAFVATHSERVTLDPARSFHGGSTAQLVDAGYDAVGLHLENGNSPFA
                     PTLTWFFCEKAASSGSQTTVCDGYRVWDALSDEARGLFRQHEIVYSRRVEEARWKAFAA
                     FHLGTSDAASVTVEQLQELTSGPGETVIEPLQDGAIHYAYRVPAAHETLFDTRPAFANS
                     ILGPSNHYEKPRITFADGRDIPVHILKEIESVTEELTEDLDWADGDVALIDNTRVMHGR
                     RAITDPDRTIYNAQSDLDRGLLPA"
     aSDomain        36793..37563
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CES90_RS33880_TauD.1"
                     /evalue="2.80E-34"
                     /label="CES90_RS33880_TauD.1"
                     /locus_tag="CES90_RS33880"
                     /protein_end="293"
                     /protein_start="36"
                     /score="111.0"
                     /tool="antismash"
                     /translation="CVLRDAGFLLLRGFRPDLEQFSAFVATHSERVTLDPARSFHGGST
                     AQLVDAGYDAVGLHLENGNSPFAPTLTWFFCEKAASSGSQTTVCDGYRVWDALSDEARG
                     LFRQHEIVYSRRVEEARWKAFAAFHLGTSDAASVTVEQLQELTSGPGETVIEPLQDGAI
                     HYAYRVPAAHETLFDTRPAFANSILGPSNHYEKPRITFADGRDIPVHILKEIESVTEEL
                     TEDLDWADGDVALIDNTRVMHGRRAITDPDRTIYN"
     gene            complement(37784..39412)
                     /locus_tag="CES90_RS33885"
     CDS             complement(37784..39412)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012363.5"
                     /locus_tag="CES90_RS33885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carboxylesterase family protein"
                     /protein_id="WP_189787361.1"
                     /transl_table=11
                     /translation="MHPADPGPATTAIEAIESVEAEVSGGPVIGRREGPERSVAAFRGV
                     PYVAPPVGPYRFAAPRPHAGWSSPLRTDGPVGTVPPQLPSPFAALMGDPVGPDQTEACL
                     TVNVWAPLTGRGPYPVLVWLPGGSFLTGGADLPRYDGAELAAQEEIVVVLVNYRLGALG
                     FLSPSWAEPAAIEGAGTSLTFRATGESGHVTNAGLLDQIMALRWVRREIHAFGGDPHRI
                     TVIGQSAGGQALAALLALPQVRPLFRRAALHSAPLGMPPLSRAEAARTADALLAALSAD
                     GNADGIQALRTVPSERILLAQRQILARPRARGDVRPPFQLVADGTVVGPDLLGALRSSP
                     PLHGLDVLAGTTRHECALWYGMDASLAAMTREEVAEEFAGQFGDRAEEALRLYTSGPAD
                     RPAAFEELKTDAFFAAPTQEFGDLVQERGAAVRLFRFDWEVPGRYSALRACHCLEIPFL
                     LGRPEARRAPLFADAEPADLSGLRAEVRRLWGSFVRTGSASDAWPQHRRERPAVRVIGG
                     ERNGVLLRSLLEPVREALWTDRGAN"
     cand_cluster    38371..49396
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    38371..49396
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[43370:44396](-)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(43371..44396)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
     gene            complement(39452..42370)
                     /locus_tag="CES90_RS33890"
     CDS             complement(39452..42370)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.5"
                     /locus_tag="CES90_RS33890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="BREX system ATP-binding domain-containing
                     protein"
                     /protein_id="WP_189787362.1"
                     /transl_table=11
                     /translation="MPRSGHQRLVGRDRELAVLRSAFEATAAGRGAFLVFHGQFGSGKS
                     LLLHTAAEEAERRGMAVSSARVARLDRHSAMAPLLAVLRAGPRPVINPVQAESLAALAD
                     RPTHWGRLIDLLRRLIEQRAAHSPMVIVLDDLQWADELTVAALETLLPRLADAPALWLA
                     SYADFPVARPARGALDRLLTSHAEVVRLSPVDEAAAAELGARLLGCARPEDVRRLTSAA
                     GGSPFLVDCLVQLLREEGRVRSEEDGTVRVVGRHLPAGLGRATAPVVSGLSQQTHDLLQ
                     VGAVLGRQFSLRQAAALTGRSTMELATAAQEAAAAGLLEDDGVAFRHRSPLVHLAVYGS
                     LLGPVRRALHSEAARLCVSEGRPCPETLAHLILAGAEEDLEEGVARLKWLERNDESVPT
                     REQEELARALLERLRLYEPLSAAPVTTAVQLFLTAGRTAEARHLLDAALAAAGWETEAE
                     AEAFAELLEVLLQLSGARHALRHLRRARKGARPPVSHQAWLMVLEARCLLAYSAGDPGR
                     AAALSWTAVSLARRAGDQASVVLGTAVLSLCARHTGDIAESLRLAGEAVAHGPVDTQRS
                     LGWGSLWLSLTLCLAGRPLDAAEVLEAWRDGAGAGDRVWTAPRWHIAKSLQLWHSGRLE
                     EAAREAHAGLEASARLADPAARTFLLGVLALVTTVRGDLETAAGHVAALSSTAHTALPG
                     LTGTLYAFVTALRLDAAGDPGSAMRQLGTVWSALDLHLWFLTADPMILPHMVRIALRAG
                     AGERAAEAVAVARRLARRNPGVTPLVGAALHAHGLYRGLAAPLHRAVRVFRTGSHPLAL
                     ASALEDAAAVTQAQGDLVRATEMLQEAQRVYVASGAGLGAERVRRRLRSAQGRISEAAA
                     TDGVQALPGSPAPAARPAAQDPAHTSADWDSLTPSEIRVVRLVAEGLTNRETAQRLAVS
                     AHTVDSHLRRAFAKLGVSRRVELARYVLAHGTSGQVPAHSPK"
     misc_feature    complement(42434..42449)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.33"
                     /tool="antismash"
     gene            complement(42469..43182)
                     /locus_tag="CES90_RS33895"
     CDS             complement(42469..43182)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019349.5"
                     /locus_tag="CES90_RS33895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="WP_189787363.1"
                     /transl_table=11
                     /translation="MPLRPIGRSSTTREVLALLHGELAAGTWPVGSRIPSETELAAALG
                     VSRPTIREAVSALVHTGMLKSQRGKGIFVRSVSDPAPMLQSIELADVRDVFEVQLCFDV
                     QAAHSAALRRTPEDMARLWELLQARREAADREPTEFGKRDAALHLAVVQAAHNVTLTEC
                     YRFFVKRLQESLDLFGGEDTQLECGIEAHEALVQAIQEQDAEAAATAARHVVRTSLHAL
                     EGLLAVRKAAQGRSL"
     misc_feature    complement(43195..43209)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.04"
                     /tool="antismash"
     gene            complement(43371..44396)
                     /locus_tag="CES90_RS33900"
     CDS             complement(43371..44396)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010270946.1"
                     /locus_tag="CES90_RS33900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_189787364.1"
                     /sec_met_domain="AfsA (E-value: 8.2e-17, bitscore: 60.2,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHSSARTVLPTADLQRFARKSKPDEVFVRTWREVSPQTHVVTLGW
                     PPSHDFYTLRSGVTSPLFFVETVRQALAVLSHTSQEIPLDHRLGWEYAHYAFAPAALRE
                     RHAPTDVELRITHGDITRRRLGSVHLTARIDATCAGEPLGSSEIRYVTHPPAIYNRLRG
                     EYADAQQAFATALPPAPPVPPSLVDRSAPGDVVIAPTARPHHYQLRTDTSNPVLFDHPH
                     DHVPGMVLLEAAAQAVHASAPGHARPAAFDSTFLRYVEFDAPCWLDLTPKAPDGYGRSR
                     LVVTGTQNGQEAFSTTVTLESTSVTVESASTLEATATTAVEPGGLARVDRAAVLDASPA
                     Q"
     misc_feature    complement(44370..44372)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(44490..44510)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.39"
                     /tool="antismash"
     gene            44539..45168
                     /locus_tag="CES90_RS33905"
     CDS             44539..45168
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010270948.1"
                     /locus_tag="CES90_RS33905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_189787365.1"
                     /transl_table=11
                     /translation="MVGRVIKQERAARTRVALLHAAAEVFAESGFAGANVSNIAERAGL
                     TLGALYFHFRNKSDIAREIVLNQPDLVLPPHPSQGLQHAVDITLTWAYQLIDDPVLLAG
                     ARLVMEQEHFVEAEENSHQQWTRILGQDLREAQQRRELRAGVDVEALARLVVNACTGAQ
                     MHSHLETKRRDLPYRIEEMWRCLLPAIAVPSVIKRLEFGESRARKA"
     gene            45168..46037
                     /locus_tag="CES90_RS33910"
     CDS             45168..46037
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672606.1"
                     /locus_tag="CES90_RS33910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_332836407.1"
                     /transl_table=11
                     /translation="MAGMGERPLIVVSGATGAVGRHVAALLEGRAQVRLLVRDVGKARA
                     LGLTGEIVAADYADRPLLDKAMTGADAVFVVTANPLRPEHDENLLAAARLGGVRHAVKI
                     SWLGVADPGADDLIARWNRDSERLLHTSGLDWTVLRMRSPMSNTLAWAPAIRQEGVVRA
                     LGGDARTACVDPRDVAAVAVRALTRPGHEGRTYALTGPEPLSPREQTRVLSRVLQRPLR
                     FEELTLNQALDGWRRKLPEPVAHALAEAAARRGAVAAAHPEDTVAAVTGRTARTFATWA
                     GDHTAYFR"
     gene            46167..46922
                     /locus_tag="CES90_RS33915"
     CDS             46167..46922
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (5-180). E-value: 1.1e-15. Score:
                     49.9. Matches aSDomain:
                     nrpspksdomains_CES90_RS33915_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672605.1"
                     /locus_tag="CES90_RS33915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_189787366.1"
                     /sec_met_domain="adh_short (E-value: 6.8e-35, bitscore:
                     119.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.2e-31, bitscore:
                     109.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTGRTIMVTGASSGIGEAAARLLAAEGAAIVLMARRADRLRELA
                     RNIEDKGGRAAVSVGDVRSAADVERAVSTAVDTFGSLDGAFNNAGWGTIGPPLHEMDDA
                     DYDRMMDVNVRGVWNCLRKQIPVMLAQGSGGSIVNTSSTAGLFATGASAPYVAAKHAVA
                     GLTKAAAAQYGGQGIRVNALMVGSTRTELMDAAIQSNPQVEEHSVARAIQRRLADPQEV
                     AQAVVWLCSDRSSFVTGATVPVDGGCSAI"
     CDS_motif       46182..46277
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CES90_RS33915_0001"
                     /evalue="1.70E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="CES90_RS33915"
                     /protein_end="37"
                     /protein_start="5"
                     /score="17.5"
                     /tool="antismash"
                     /translation="TIMVTGASSGIGEAAARLLAAEGAAIVLMARR"
     aSDomain        46182..46706
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CES90_RS33915_PKS_KR.1"
                     /evalue="1.10E-15"
                     /label="CES90_RS33915_PKS_KR.1"
                     /locus_tag="CES90_RS33915"
                     /protein_end="180"
                     /protein_start="5"
                     /score="49.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TIMVTGASSGIGEAAARLLAAEGAAIVLMARRADRLRELARNIED
                     KGGRAAVSVGDVRSAADVERAVSTAVDTFGSLDGAFNNAGWGTIGPPLHEMDDADYDRM
                     MDVNVRGVWNCLRKQIPVMLAQGSGGSIVNTSSTAGLFATGASAPYVAAKHAVAGLTKA
                     AAAQYGGQGIRV"
     gene            complement(47420..48604)
                     /locus_tag="CES90_RS33920"
     CDS             complement(47420..48604)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024935.5"
                     /locus_tag="CES90_RS33920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_189787367.1"
                     /transl_table=11
                     /translation="MPALAPAPTLAAPCADLLTSFASNVFGYLPRSDQRRWASAYLRGL
                     LTAQGKKTIRQIARASGAPEAAHQALQQFISASPWDWTTARELLAQEAAARLPGPVWAM
                     GLTVIEKRGDHSVGVHRRVVPESGRTLNCQVAIGLFLASDSRSIPVDWQLLLPDGWLAD
                     EPRRSRARIPGWAAEQPAWARALDSADRLSTPWISRRTTLVADLCVGVDPVRLAAQLTA
                     RGRDFLIEVRPSQRVAAHRARPAGVVPEGFVEAQQLLRLAGLRHPHPLGSDHSGHGRRA
                     AVRSSLVRLPGGGPTSHGGQRVHRLFAEFLPMRPRPHRYWITSLVDHRIADVVPLTHRA
                     ALTHGAIRTLENDYGLLDFEGRSFPGWHHHMTLATAAYVYDHLRHDALDHQAAA"
     misc_feature    complement(48392..48394)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(48630..48639)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.59"
                     /tool="antismash"
     misc_feature    48640..48653
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.1"
                     /tool="antismash"
     misc_feature    49020..49035
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.34"
                     /tool="antismash"
ORIGIN
        1 gaacaaggtg acttacctca gcagcgatgg cgcaacggtg ttcttcatgg cgctgcgcgc
       61 cgccgggcgc acggcacgcg cgtaatcgtc acacacgcac cggtcccaag cccgggccac
      121 cctcgaagga ctggggctgc tccgcgtctt cgaggtgcac gaaggggata ggtcaagttg
      181 ctcgtcatgc aagggcgagt agctgctgac cctttgcaat caagcgacct caacacttcc
      241 cgaatccggc atgaacaggt gctgatgcgg ccgcctgacg tgttcgagga gacgtactgc
      301 aacaaggcgg gggagccgaa tggcagcgag tggcgggggc agtgggctct tctcgatggc
      361 ctggggaata tgggcaaccg gcttcggctg gatcatcgcg tcggacttcc gaggcgcagc
      421 ccaccggttc tatgagctgt cacagcggtc tgtgccgttc agcgcgagga gggcaccact
      481 cgtcggcgtc ggcttcctca gaatcctggc cggtgtgttc gccctcatcg ggcctgccgt
      541 cctcgtcggc gggctgctcg aactggttcg aggcgaggga gcttccgacc ggctgccaca
      601 gttgcccgta ccgctcgcgg cgacggtggt cctcgtcggc gccttcgggc tgtggacggc
      661 gtggcggcct tccgggctgc ttcgccggga gtgggctgag ggcgccgacc tccagcgcgc
      721 cgccgttgcc gtagtcaccg cggcgctcgt cggcttcccg gccacgttgg cactcggcca
      781 ccagacggcg atgctggcca gttggctggg cggagggctc gcgggtctgg ttctcctgct
      841 gagcggccgt ttcatcttcg ccgagcaagt ccaggccgag ggcttcgccc gtctgcccgg
      901 cctacgcgac ctcgtgctcg accctgccgg gaccaccctg cgcggacagc tcactggcga
      961 actcgacgcg ctagtcaagg ccgccgcccg gcaccacgtc accgcgctgc gtgtgaccga
     1021 acccgccctg gacgacctct tccacgccta ctacacggac gccgaggccg cgccgtgtcc
     1081 gaccgccgcc gtctgatcgg ccacccgtcg ctcacctcac cttcgccgaa gaagtcaact
     1141 cgccatgcct gccactgtgt tcaccatgcc cctccacgac aaccgccctc cctcatcggc
     1201 tggacggccg gcaccaccct ggtcgccgcc atgtacgcga gcttctaccg ttcctgggga
     1261 ctgagcggga gtaatcccaa tcagccgcac gccccgaacg gtcttggacg ctcccccaga
     1321 cttcgtccgg gggccccagg tccccggcgt gcataggcgg cgagccgctg aagcacggca
     1381 tccagtgggc cacgccggca tcctcgtcgt agcgtccacg gtgctggtag ccgcgggggc
     1441 gtaccgcttc aaccaccgtg acctcaacgc ctgacgaacg gacaggtctg cggagtcctt
     1501 gcgcacaaat gcccgatacc ctcggtgatc accggccttg atcaggccgg tgatcacatg
     1561 gggagagggg aaccgtcatg gcgcgtaagc cggttcgcgc agcggtcggg gacatctgga
     1621 tcagctgtca ggtctgcagg agcgatctgt tccgggaacg gggcgtgctg ctgaacagcg
     1681 tcggcctgga gttcatgaag atggcgtggg cggacgagac ggcaaccggc ctgatctgct
     1741 ggcggtgcgg attcgtccac ctcttcgtga acaaggacat caagctgtac cgcgcggaca
     1801 agtgacagcc gttccgacgg ccatgggctc cccatctgct ggtcgctctg cggcccgttg
     1861 ccggggctgc ctggctgact cactcagtgt gggggaccgg tgtggccagg tcctccggtg
     1921 ccggggtgcc ggggtgccgg ggtgggcggt cgctgtcggc agcgtgtccg ggacgtcctc
     1981 cgggtctgga cgaacatgca ggatcagctc acggcccggc cgctgtccag ctcggccgga
     2041 tcgcttcagg cgagcgcgac gggcgccctc gccgcggcct gtgcggtctc ggtcgtactg
     2101 ggtggcggtc aggccgttca ctcccttctg gaccggcggc gtctgcggca gtgggacaaa
     2161 gcccgggcag aggctgacgc tcggtggggc ggaaagaccg tgtgatcgcg gcccgctgtc
     2221 ggcgcccagc gcaaactcgc ggagagcggt agctcagcga tgctgaccag accggcgaca
     2281 accggctcgg gatcatgaca cgatgcttgg atggtgcggc tctccgcctg cggtggaagg
     2341 gcgggggccg gtcctggagc gccgggaagt ctggtcggca cagtgcctga acgcgacgag
     2401 ggagcaggct gtgtccgcga tccagagcgc tctgcgccgt gcgatgagtg tcgaaggggt
     2461 actgggcgcc gcgatcgtcg actacgtcag tcgcatgccg ctcggcacca tcggcaaccc
     2521 ggcaggtctc gaccttgagg aagccgctca gagagacacc gatgtcgtac gcgtgaacct
     2581 ctccgcgctc gctcagctgg ggtacgagcc caggcgggtg gaggacatac tgatcactct
     2641 ggacaccgag taccaccttc tgcgtcccct cgctcgcagg gcacacgacg ggctgttcat
     2701 ctacctggtc ctggaccgcg acctggcgga tctggacacg gcccgcaaag aactcctacg
     2761 gatcgaggag ctgctgtgag ggcgacacca ggtatgggcc tggacgaaca cccgacgcag
     2821 atcgccgagt tggcggacgg accggtcgag taccgcttcg atcggcgcgg gccggacacg
     2881 gtcgtcgtct tccacggcgg gcacatgcgg gccggacttt cgctcggcga ggaggtgttc
     2941 gccgacgccg gctgctcggt gcttgtgccg tcccgtccgg ggtacggccg caccccggtc
     3001 tcgaccggcg gctcggcggg cggattcgcc gacgtcaccg ccgcgctctg ctcgcagctc
     3061 ggtatcgcca gcgtcgcagc ggtagttggt gtctcggccg gaggacccac agcggtggcc
     3121 atggcagcgc ggtatcccgc cctggtggac aggatgatcc tgcagagcgc cgtcgggcct
     3181 ctgccctggc cggaccgccg tacgcgcatg gctgcccgtg tcgccttcac ggcccggacg
     3241 gagcccctct tgtgggctgt ggtgcgcaca ctgatgcgtc acgcgcccga ggtcggcctg
     3301 cgcatgctgc tgcgggacct gacggtgctt ccttcgcgga aagccgtgtc gggtcttggg
     3361 gcggaggacc gggcaaggct gatcgcgctc ttctcccgaa tgcggtcggg ccacggtttc
     3421 ctccgcgatc tcaaagccct ggaaaccacc gcggagttga cccgtcatgc gggccaggtt
     3481 tcccagccca gtctcgtgat cgcgacctgc caggacggtg ccgtaccgtt cgcgcatgcc
     3541 cgggcacttg tcgcagccct ccgacaaacc gagctgatcg aaagctgggc gggcggacac
     3601 ttcatctggt tcggccagga ctggccgacc atcgccgacc gcatccgcga cttcctgctg
     3661 gcggacctgt acttgatgcc gcgaggggag ctgtaacgga cggccgctga ccggcaccag
     3721 gcggtcgccc cgaccatgcc gactctgccg tggcctgccc tacggccgtc caggaacggg
     3781 tccgcgagat tccagtcgaa cgcccgtgcc gatcttgctg gagatcccgc acctgcctac
     3841 tgttcagaac gcggagaggg aaacaacggc ggcggtcccg ctcgctgacg cgggacgtgc
     3901 tgtcgccaag cgggggtgaa gcgtgtccga caacagccgt cgtcttgctg tgctgtctgc
     3961 cctcccgttc gccatgatgg ccgccgtcac cgcggtcgac ctcgccgcga gcccaggggt
     4021 tggattcctt ccgctgctgt cgctgggccc ggcattcgcc agtctggtcg gtggctgacg
     4081 gcgcaccctg tgcatcggcg ccatcgcgct gctgctctgt gtcgcactcg gcctctacaa
     4141 cgacatgctc gcggcacgcc gcggatacat gaccatcgcc tccgtcgtcg gcgtgacgac
     4201 ggccggcatc gtcgccgtgg tgatgcgtca gcaacgcgag atggagttgg ccaacgtgcg
     4261 ttccatcgcc gaagcagcgc agcgcgttct cctcaagccc gtgccgcgca aggccggccc
     4321 actacgggcc gccgtgtcct acacgtcggc cgtcgccgag gcccgcatcg gcggcgatct
     4381 gtacgagatg gtcgcctcac cccacggcgt gcgtgtgatc gtcggcgacg tgcagggcaa
     4441 ggggctcgaa gcggtggaga cggcggccgt ggtcctggga gcctttcggg aatcgccgcc
     4501 ggaggaacct gatctgtccg agatggggca gaggctggag cgggccgtga accgtcagct
     4561 ggacggggag aagttcgtga ccgcaaccct cgcgggagta accaccgacg gggtgacgtt
     4621 cctcaactac ggtcatccag cgccgatggt gactcgcgcc gacggctccg tgacctttcc
     4681 cgaaccgccc gcctatgctc tcccgctcgg tctcgccgcc cacaacacgg ccgcccccca
     4741 gcccttccgg accggcttct ccgctggaga ccagctactg ctctacaccg acggtgtcac
     4801 cgaggcccgc gacgccgccg gacgcttctg tcctctcgac gaacgcgccc atgtactgaa
     4861 ggagcatgac cccgaagccg cgctggagcg gctgcggcag gatctggtgc agcatgtgaa
     4921 gggcccactc cacgacgacg cggccatgct cctgcttcgc taccgctgag ggcggtgaag
     4981 aacaaggtca agttgtgctt cacgtggacc aacgcgtcct gggcgaaccc aaggtgccat
     5041 gggcggcggc cgatcccagg atcaccgccg cggtcttcgg tctccactgg cccgatgccc
     5101 tggccgagac ggcgaagcag atcgccatcc cgatcgaatt catgctccag cgggacgatg
     5161 agcacatccc gcgccagtcc ggtctggcgc tgttcgacgc ctcgcctcga aggaggagac
     5221 gctgcacgcc aacgcgggca cgcacaagga cctgcccagg tcccaggccg cagcactgcg
     5281 gtgttggtca ggggttttcg gcggctagcg gttttcaacg acggtcatga gcttgtcgcg
     5341 ttgttcttcg tccgcgagtg cgatcagtct gttctcgaca tgcagtggca ggtctttgac
     5401 accaagttcg acgccggact tgtgcgagtg gtcgatgaag gtcagcaacg ccttggcccc
     5461 ggacatgtcg atgtagtcga cgtgcttcag gttcagcgac aggttcgacc ggttgttgcg
     5521 gagggtggtg aagacacggt cgatggacag gaacgacagc ggtccctcga tgtggtaggt
     5581 cccggtaccg tcgtggacga tcgaggcttt gtgccggcgc gatttcacgg cgtgcacgat
     5641 gagtgccagg acgacgccga cggcgaccgc cacggtcagg tcgacgacga cggtgatgat
     5701 catcgtcgcg aacatcacgg cgacgtcacc tcgcggagag acgtgcgctt tgcgcaggct
     5761 ctcccagtcg aacatgccga acgcggtcag aatcaagatc cccgacagca ccgccagcgg
     5821 aatgtactga acgacagccc caagtccgac cacgagagcg aggaggatga cgctgtgcgt
     5881 ggccgccgac agtgcggtgc ggccgccgct tctgacattg atcacggacc tgacggtcgc
     5941 gccggcgctg gccaggccgc cgaacagtcc gctggccgcg ttgccgagtc cctggccgat
     6001 cagctccttg ttgctgtgat gccggttgcc ggtgatgttg tccatgacga ccgaggtcag
     6061 cagcgaatcg atcgagccca gcagtgcgat gctgagcgcg ggcaggacga gggtgaggat
     6121 caacgacccg ctgaactcgg gaagggtgat cgaagggatc gactccggga tctttcctat
     6181 gtagtcgatc gccgtgttga gcgagaccgg tccgacgcgc acgtcctgca acagcgagtc
     6241 cacgagccgc aaagccacgg tcatgaccac gagcgcgatc agactcgctg gaatcgactt
     6301 gatcacccgt gtggatacga gcatgagcac gatcgtcccc gcgaccacca ggaaactctt
     6361 ctgcacctgg tccagttcgc ccaggatgat gatcagtgcg atcccgccca tgaaacccga
     6421 caccactggg tggggtatgt agcggatgag ggatccgagc ctgcacagcc cgaacaggat
     6481 ctggaacgcg ccggccatga tgaacgcgag gaatgcggcc tcgagtccat gcgtggcgat
     6541 gactccggtg gcgacgacgg tgatggggcc tgtggggccg gtcacttggg cgggagtccc
     6601 gccgaacagt gccgcgaaga acccggcgaa gatcgcgccg tacagtccga tgagcgcgcc
     6661 ctcggaggtg ccggtcgcgg tgatgccgaa ggcgatcgcc aatggcaacg ccacgatcgc
     6721 gacagtcagg ccggagagag tctctttggc gacgcgctgg aacatcggcc cccacttcgg
     6781 tcgacagcat gctggcctcg gcccacggcg gaccgagctg ccgaccaggc ttcccggcac
     6841 tccgcgagta aagatgccgt atagaacgcg tcaaggcaag atcaaagatc gccatgtggg
     6901 tctgctagcg cgccaccagt gcgtcggcgc cctctgttga gcttcgttgc gcgatcagcg
     6961 gccccgagga catgcatcgg gtcccggctg cggatgcgct gccctgacgc tgttcagcgg
     7021 ttccagcatg ctggtctgcg gtgatcctgg ttggcgaagg ttctgtgcat ttcggacgcg
     7081 ctgaagcggc ctcgggaaac ggtgtgaacg ggcctctggg gtgcggttgt tgtcgcgatc
     7141 ggggcctcgg catgatggac gtcgcatgtc gtgaatcgcc gctaccatcg cctctccgtg
     7201 atggggctca gccgggatcc atgtcgcgat atagcgctag ccttctgtgc gcgtcgctgc
     7261 ctgcgtcgcg cggagacgtt cgacgggacc gggatgggaa ggcatgtcgg gagagatttc
     7321 gcccaccggg aagcactccg gccccagctc gtcgcccggg ctgcgagcct ctcatgccga
     7381 ccgggaccgg gtggtggatg tgctgcgtat cgcggcgggg gacggcctgc tgaccgcgga
     7441 cgagttggac gagcgcctgg aagctgccct gtcggcgcgg actgtcagcg aactgaccgc
     7501 gctcaccgcc gacctgccgc ccgtatcggc tacggctggc gcgactgtgc cagaggtcaa
     7561 ggacgtggtt cggatcgaac aggtccacag cggcgcggtc gagcgcgtgg ggcgctgggt
     7621 ggtaccgcgg aggctggagc tcgcggtgac gtactgcgag gtgacacttg acttcactga
     7681 cgcagtgatc acgcacgaca ccctgcggat cgacgtggcc atgacgggga agaccctgac
     7741 gctggtcacg aggccgggca tcgtggtcga tacggatggt ctgcagctgg tacacagcag
     7801 ggtcaagtac cgtcagactc cgacgaaccc tgatacgccg gtcactctgc gagtggagct
     7861 ggtcggtcaa aaggtctacg gccgcgtggt ggtgcggccc aggcgtcgga cgctcggaca
     7921 gtggctgctg cgcaggccaa cgtctcgttc tgcaggcgct tgactccatc gttgtgaact
     7981 ggcggcgggg ctggccgctg aggtctcctg tggtcagcgc ggacctggca gccgcacgct
     8041 ccctcgtcaa accggacggc cgggtgatcg cggtgttcca gccgtccgac ctggcccggc
     8101 tggaggcatt cgacgtcgac ctcgggaagg cgctggccag ctgcgacgag gccgtgctga
     8161 cgggcagccc ccactgcgtc acctgggcgg cgctggagag gttgtctgcc cgggtcaaca
     8221 acgccggcgg cagcgcgagg cacatcgcgc cggaccggtc cgagaccgtc ggcgacagac
     8281 cgctggtcgc gcccgccgtc gtccacgacg attgcgggga cgccgacggg atgggtgacg
     8341 agggccgcgg tggccccctt gttgacggcg gcctcagcat aagtgtggcc gtctgcctgc
     8401 tcgcccttga gggcgaggaa cagcgatccg gggatggctt cgcgggagtc gaacactgct
     8461 tcgcgggagt cgaacactgc gggttcggtg atctggacct cgaggtcgag gacgtcggcg
     8521 agacggccgc cgatgacgct gacgatcgtg gtcacagaca tggggtgcaa cgtggttctc
     8581 cccggtcagg tggatggttg cgacgctccc gggcgggagg cggccgtcag ggcagtcctg
     8641 cgccgtacgg tgctgcgagg gtcgagtgag aggcaccggc cgccgaagaa tgcgccgaag
     8701 cggtccagag gcatggtggg cgcaagggcc tcgggggtgt gtccgctcgg gttgcggagg
     8761 atgatctgcc cgtctcggcg gccgatggcc agaacgaggt gcccgccacg tcgctccggg
     8821 gcgatgtccg ggcggcggat ctccttggag accgagacca tcaccatccg gccggcgccc
     8881 aggaggtcga cgagaccgtc caggtcgagt tccccgtgca cttcgccggg aagccggtgt
     8941 gtgtccgcca cgtactcgac gaacggcgca tagatcaggc ccttgatcgt gccgtcatcc
     9001 tgcttgacgt acgcgccgta acggcaggcg ccgttgagga gctcgaacat gctcggcgcg
     9061 tggccgtcac ggtgcaggag caccatgcgc aggcaggtga tgccgcacat gtgccggcac
     9121 cagcgcgcgt atatcttctg ggtcggcgca ccggccgcgg ccaccaccag tcgggtgtcg
     9181 gtgtccacga tgacctgcac gttcgccgag aacctgtaac tacgcgagga cgcgcccacg
     9241 ctccggtcgc ggaccgggac cagggtgccg tccacgatcc acagccgatc gggatcatcg
     9301 tctggacggt cgacaggctc gagcgcaagc agcggcccca gccgttggat gatccggcac
     9361 acggcggagg aggagacgcc gaacagaggg ccgagctgcc gcatggtgag gttggtgcgg
     9421 tagtacaccg cgaccaccag cactcgctcg gtcagcggca gcgaccacgg ccggcctcgc
     9481 agggtgccgt tgccgccgcg ctcccgcact acctttaaga gacgctgaaa ctgcgtcact
     9541 cgcagccagc gcacccaggc tgatctgcgt cgtcggcgac cgacgcgtcc atgccttcgg
     9601 cccggtgcgg caccaccgat ccaccaccgc gctccgcgcc ggctccgcga caacacaaga
     9661 cggctcggcc agcacctcgg ccaccgttgc tcgggcatcc accagccgct gaagcgcagc
     9721 ttccgcctcg tcgagcgcag cccgcaaccg cgccacctcc tcctgggcct tcttctcccg
     9781 agcctccagc agaccgagca ccgagggcac cagccacctc cacgagcgac gcgagcggac
     9841 caaccacgcc catctctgga cggccaccgt gtcgccggag tgacaggaac cgtcggggga
     9901 gcagcaggag ccggtgttct atacccccta ggggtatctt catgttcgtc gagtctatac
     9961 cccacgtcgg atgcgcatac cggccgcgag gtcgaggacc tgaccttcga ggtgagcaag
    10021 cacggcaagc cggtgaccga cctccagccc tacctcggcg cctacgggca cctggtggcc
    10081 ctgcgcgccg gagacctcgc ctacctgcac gtccacccca acgacgaagc cgggacgaag
    10141 cccaggccga ccatctcctt caccgccacc gccaccccca ccgccaccgc caccgcgcgc
    10201 acgcctaccg cctcttcctc gacttccagc acggcggcac agtgcacacc gcgagtttca
    10261 ccgttccggc gggcctcgga accgcccccg aaggcgatga ccacgaggcg gacagccgct
    10321 cggcggagca ccaccacggg tgacgcgacg tcggtggcta cgccacggcc gaccggcacg
    10381 cacagggacg gccggagtct ccgccgcgcg ccgagacttc ggccgtcccg ctcgtcctac
    10441 tcgcccttcg gcgggatcag ccacatcgag acgagtgcgg agaccgcggc gacgcccatg
    10501 gccacgagga acgcgtcgtc gaagccggac gccgagctgc tgccggcgat gctcgcggcg
    10561 gcggcactgg aaacggctgc ggccccggcc gcagcgccga actcgtggaa ggtgctgacg
    10621 actccggagg tcacgcctgc ttcgtgcggg gcgacgctgc tcagcgccgt ggccgaggcg
    10681 accacgaaca gggcgcccag tccggccgag gagacgctga ccccggcgac catggcgacg
    10741 gtgccggccc agaacaccgg catgaggaag ccggcggccg cgatcaccag cgccaccgcg
    10801 gccatggccc gggctcccag acggccgatc aggcggccgg cgacggtggc gcaggccatg
    10861 gtcagcagcg ccacgggcag gaacagcaga ccggccgcca gggcgccgtg gttctcctgg
    10921 ttctggaggt agaaggagcc gaggaagaag acggccacca tcagggccgt ggtcacggtg
    10981 atcacgaagg tgcccgccac cactgggcgg cggccgacca gtccgaggtc catcaggggc
    11041 gccgacgccc ggcgctgcca cgccgcgaaa gccgcgtaga gcacgacgga gacggcgagc
    11101 agggcgaggg agacgccgtt gagccagccg tggtcaccgg ctcggatcag ggcgtagatc
    11161 agggcgccgg tcgccgcagc gaccagggcc gcgccgggca cgtcaaggga gccggaggcc
    11221 accttgggga ggtccggcag gatccggatg agcgcgacga ggatgaccag gccgacgggg
    11281 acgttgatga agaacaccca ggtccagccc ggcccggccg tgatgacccc gcccagcagc
    11341 acgccgaggg cggcgccccc gccgccgagc gccgaccaga ccccgagcgc ccggttgcgc
    11401 tcgtcgccgt cgaagagccg caccaccacg gacagggccg cgggcgacag catcgccgcg
    11461 ccgacgcctt gggcgactcg ggaggtgagc agcatgggcg cactggtcgc gagtccggcc
    11521 gtgagggagg ccacggtgaa gaccgtgagc ccggccaggg ccaccccctt ggcgccgaac
    11581 aggtcggtcg cccggccgcc gagcagcatc aggctgccga aggtgagtgc gtatccgctg
    11641 accacccagg tcacggcggc gcggcccaga tccaggtcgg cctccatatg ggggagcgca
    11701 atggcgacca cggtgaggtc gaggatcagc atgagctggg ccagccccag caggcccagg
    11761 gcgagccagc ggagagggtg gggcgctccc ggtgcgtatg tgtctgcggt tctcgtctcg
    11821 ctcatgactg tcaacccctc agtaaaccga acagtgatgt tcaggttagc gcatacagag
    11881 agctaaccca aacagcagtg ttcgtgttaa tgaagtagtg tgggtggcat gagcacgaga
    11941 agcaccgcca aacgcgcgga cgccctccgg agcatcgacg cgatcgtcca ggccgccacc
    12001 gaatgcctgg gtcacaaccc ggacgcgagc ctcagtgaga tcgcctctgc cgcgggcgtg
    12061 ggccgggtga cgttgtactc ccacttcgcc tcgcgcgccg aggtcgtcga cgccgcgctg
    12121 acccgggcca tcgaccaggg caacgcggcg ctggacgccg tcgacctgac cggcgatccg
    12181 cagctggccc tcgcgcgcct cgtcgacgag agctggcacc tggtggacca ggcgcgcgcc
    12241 ctgctcgtcg ccgcccagcg ggaactcccc ccgggccgca tccgcgagct gcacaacggc
    12301 ccggccgccc gggtcgagac cctgatcacc cgcggtcgcg ccgaaggcgc cttccggacc
    12361 gacctgccga tcccgtggct catcaccgtc ctgcactcga tcatgaaggg cgcggccgac
    12421 gaggtccgca ccggcaacct cacccccgac cgcgccgccg cccacatcac cgccacggtg
    12481 ctcgccgcct tcacaccgcc ggggaagcag gtcccggagc ccgacgggga gaggtgaggc
    12541 cgccggccgt gacgtatcca ccgacggcca cgccccggcc gtcgagaacc cggagcaccc
    12601 ggttgaaaga aagcgccgac gacaccgcct gccgactcca ctggtggtac ggcctgatgt
    12661 cggctcctca agccattcct tgtcgcgcgc gaggaacgca accggccgga ccgcgctccc
    12721 gacgccaggc ccgaccggtt cgcccttttc ctcagcgcgt cagggggttg ctgctcggac
    12781 gggtggacag ccgggtctgt gtcgtcgcgt cgagaggcaa ctcgatacgg cggtcgatgc
    12841 ggtcgtcggc ccatgtgcgg gtgtcgatca gccaccagcg ctcgacggtg accacgtaga
    12901 gccggtgcgc ggcgggcggt cgcagcagtt ctcgcggcaa ctgccactgc gcacgctgtt
    12961 cggcgtcggg gaacaccgtc tcgtagaacg gcgtgtagta ctcctccagc aggtcggggc
    13021 cgatttcgga gcacaggccg gtgaactgag ccccgtcgac gggcgcgatg gccactccgg
    13081 ccgcgcccgc cgtgacgaac agcgaaccgc tcacgcgggg ctcgcggtcg atgtcacggc
    13141 tgtgtcggga tccggtggtc gagccgaaga cgaggcgcag cggaccgggg aaccagacgt
    13201 actccagggt ggccacccag ggggttccgt cccaggtggt ggccaggttc agataccggg
    13261 cctcgttcag cagccgcgcc gtccggtcgg tcaggctcgc ttcgatcgcc atgcggggac
    13321 ctttcgctgt tgtggcacga cggtggttca cccgccgtgc ggagccgggg cgggcgtcac
    13381 ctgtgccgca ggaagacggg cagggccgcg atgtcgttgc cgatgaaggt gggtcccggg
    13441 ggcacgtcct cgggctcgac ggcgagggtc aggcgcggga aacggtcgaa cagcgcgggc
    13501 agcgcgatac gggcctcgag gcgggcgaga cgcgagccgg ggcagaagtg agggccgagt
    13561 ccgaaggcga ggtgctcctt gtcctcgcgg tcgatgtcga aggtggcggg atcgtcgtgg
    13621 acctgggggt cccggccgtg ggctccgtag cagatgagga tggcgtcccc ggcgcggatg
    13681 acgacccctt cgccgaggtc tatgtcctcc gcggcccagc gcatgggcag gtgcatcacc
    13741 gggcagtgca cgcgcagcga ctcctcgatc gcgtcgtccc atcgggccgg gtcggccttc
    13801 aacagggcga gctggtcggg gcggacgaga agttcgcgga tggtgtggtc gaggaggttg
    13861 atggtcgtct ggctgccgcc gccgatcatc agaagcaacg ttgacacgag ttcgtgctcg
    13921 tcgagcgact cctcgccttc ctcgcgcgcg ttgatcagga aactcgtcag gtcctctccc
    13981 ggcgtacgcc gcttggtgcc gatcaggagg tgcatcgccg cttcgaggtc gtgatagagg
    14041 gcgatcgact cctcttcggt caagtcagtc ctggccacgg cgcggaacac ccgcagcacc
    14101 tcaggccgtt ggtcgtccgg aatgccgaac aggtcacaga tcacctgggt cggcacgcag
    14161 taggagaact cctgatgcag gtcgacaggc tcgtcgccgg ggtgcgcggc caacgcgtcg
    14221 agcagcatgg cgacatcggc ctcgatgtgc ggccgcagca tctccacccg gcgagggctg
    14281 aacgccgggg tgatcagctt gcggagccgc gtgtgttcac ggccgtccgt cgtggccatg
    14341 gagtccaggt ccacccacgg ggacagccag gggacggaac ccggctggta gctcggcacc
    14401 gtcttcttca ggtcccgcga gacgccgggg tgcgtcagga gcctgcggac gacatctcct
    14461 cgggacaccg accacgctcc gaccccttcg ggcagttgca cggcgacggc cggacccgac
    14521 gctcgcaggc gctcgacctg tgcgtacatg caccggccgc ccgtactctc gatcgtctcg
    14581 gtggggactg cgctgaagtg gatcactgtc tgcctcctga tgaggccgga ctgcgacggt
    14641 cgaggcggcc tgaagcccgc ctcgaccgtc gcagtccggc cgtgtgggtg tacgtcggtg
    14701 tggtgttgcg gaccggaacg ctggaaatgt cgtgcgggac tgcggagtcg acccgctcag
    14761 ccgtcgtcga ggccgcgggc caggcagctc cagaacgctt cttcgagggc atgcaccgtc
    14821 cgcgcgcagc gcacggcggc ggccggatcg tccccgccgg ccagcccctc ctccagcgtt
    14881 gccgtcgcct ggtccagcag cgtctgcgga gtgtcggcga agaacaggaa atgcccgagc
    14941 gccctctcct cgaacccgta ctgggacgca agcgcctcgg ccacgcgggt gtacgtcgcg
    15001 ccggactccc tcacgttcgc caagagggcg agcgcgacgt cgctggacgc gccgtacagc
    15061 gcggactgcg tcagataggc cggatacgcc tgcgcgagcg gctgcggttc gtaagctcgg
    15121 acgtcccgct cctccaggtt gagcgccgcg gcgaactcca tgagcagcct cagcgcctgg
    15181 gcctcgcctt cggccatggc caggtacagg tctccggccg gagcggaggg aaagcgggag
    15241 gcgagcagcg cgaaactgcg gcgatcgctg ctgacgagat ggtgcagttc cccggcgagc
    15301 caccccagcc gttccttggg cacccggccg tgctccaacg cgtcgacgaa accgttaggc
    15361 ccggcctgcc ccgcaatctg ctgccgcgcc gccgcgacga catccgtcac ggaattcact
    15421 gagccctcct cgtcggtccg tcggacatcg atggggtggc ggtcagggag tcggcggccc
    15481 ggaggacccg ccgcagactg ggcaccttcg ccggccccgg ctccggttcg gcgatccagg
    15541 gcccgtcggt ggaagggtcg accacaccgt cctcgagcca ggtgtggtca ccgcccagca
    15601 cgctgtgcgc gaggccccgg tcctgctcgt cggtgttgtc ggcgagccgg tcgaagaggt
    15661 gcacgatcct caggcgcgcc tgccggcaga aggcgtcggc gagccgggcc gcggaggcgc
    15721 cgacggcatc gagggcttcg gcatagacgc agctcgcgct catcgcgtac aactcggcgc
    15781 cgatgtcgac gatcctgccc aggaaacgct gacgctcgtc gatctccgtc gtcggcccct
    15841 cggcgatcgc ggcgagttca cgagccagac gccgggaggt ctgttcgacg aatgcgaggt
    15901 gggtgtccag gacacttccg tcgccacgtg cccggcggcc ggtcgggacc gcttcccgct
    15961 gccccgccga ggagcggtgc gccgcgatca ggtcgtgggc gaggaagccg cgaagcgcct
    16021 cgctggagcc gtcgaagatg cgaccgatcc ggacgtcgcg aaggagctgc tcgaccggga
    16081 ttccccgctc gccgcgtccg gccgccgact ccgcggtctc gtagccacgc ccgccccgga
    16141 tctgcacgag ttcgtctgcg acgacccagg cctgctccgt cgcgaacagc ttggcgagct
    16201 ccgcatccag ccgggcgtcg gtgtccccct gctccgcctg ccggccgatg acctcgacca
    16261 tcgcttcgag cgcgaacgcc gttgccgcga tgaaggacag cttgccggcg accgcgtcgt
    16321 gctgcccgat cggccggccc cactgcaccc gtgccgcgct ccactgccgg gctgtactca
    16381 ggctccactt cgccgcggcg gcgcacaccg caggcagtga gagccgcccc gtgtcctgcg
    16441 cggcaagggc gatcgtgagg ccctcgccct ccgcgccgat cctgttgcgg gcggggacga
    16501 ccacctggtg caggcggaca gagccgttct ccaggccgcg caggccgagg aaggcactgc
    16561 ggtgctcgac cgtgactccg ggggtgtccg cctcgaccac gaacgcggtc atccccccgg
    16621 cgccgttctc cgaggcgggt accagcgcca tgacgacgag caggtcggcg acgacggcgt
    16681 tggtggtcca cgttttcacg ccgtcgagca catagctgtc cgaggccggg tcgtggacgg
    16741 ccttcgtgtg catgcggaac gggtcgttgc cgatgtcggc ctcggtgagg gcgaaggcgg
    16801 agatctccct gacgcaccgg ggcaggaact gtcgtttctg ctcctcggtc ccgaacaggg
    16861 cgatcggctg ggcgagcccg atggcctggt ggccggcgag cagttcgctg agggcggggt
    16921 gtgtcgtgct ggtgagcatc agggcacggt ggtagcagcg ggaggacagc ccgaggccgc
    16981 cgtactgccg ggggaccttg atgctcatcg ccccgatgtc cttgagccct tcgatcacat
    17041 ggtcggggat gcggtccgcg cgctcgatgc cggcgctgtc gacctctttc tcgcagaact
    17101 cgcgcaggcg cgacaggaac cgttcctcgg cgggatcaag acgccgtgga tcgccctcgg
    17161 gcagggcgag gagatccgtg ttcacctgtc cgaggaacag cccggcggcg taccccggcc
    17221 ggcgcagagg gggtgtcgtg tcgtggccgg acgggtgctc cggcgcttct cgggcggtca
    17281 tgccgcggcc gtgggaacgg cctcgatgac cgacagcggt cctgcctgcc cgaggccgac
    17341 cgaccgcacg gtgaatcctg tctcttcgag cagcgcccgg aactcgctct cggtgcgctc
    17401 ccggccgccg gccatgacca tcatgttgat atcggtgaag aacgcgaccg gcgcggaggt
    17461 gtcggcggtc tcgggcagca ccgtgcccac gatcagcagc gtggcggagt cgggcatgtg
    17521 ggcacggcag gtgcgcagga tcgcgcgggc ctcctcgtcg ccccagtcct ggaagacact
    17581 cttgatgatg tagaggtcgc cgtcgcccgg tacggactgg aagaagtcac cggcctgtac
    17641 ggcgcaccgg tccgtgaggc ccgccttgct cagtgcggcg ggggcttccg caactccgct
    17701 ggggctgtcg aagacgattc cgcgcagtcc gggccgggcg agcaggatcg ccgtgagcag
    17761 ggtgccgtca ccgccgccga tgtccaccac cgttccggcc gccgggaagg cgtaggccgc
    17821 ggcaagctgt ccggccgaga tcctggactc ctcgctcatc gcctcgttga acagcgtgct
    17881 ggtctcctca tgctgggcga gccagtcgta gatgcccgtg ccgtacgcgt ggttgaaggc
    17941 gcgctcaccc gtggtgacgg catggtggag gctctgccag gaggtgaaga agatggggtg
    18001 gcagaacatc ctggcgaact tgtggaggga gtccggggag tcggaacgca gctgggcgcc
    18061 gatgtcggtc agtgtgaagc ggccgggctc gggctccgcg gcgatgccga ccgcgaccag
    18121 cgtacgcagc agccgccgca gtgacggctc gtgggtctgg gtctcggcgg ccaactcctc
    18181 gctggtacgg gacccggatc cgatcaggtc ggcgagtccc agttccgcgg ccacgccgat
    18241 ggcgtgcgcg gtcatgtatc cgccgatccg ctcgatcagg gccgcgcgga ggttcatttt
    18301 ctcggtggcc aggacgtccg gggaagctgt gctgctcatg ggggagactc cttgtcgtct
    18361 tgtcgtcggt gtcgctcggg gccggccgaa gaggcgtcag ggacgcgggg cggtgaaccg
    18421 gtgcctgacc cagacgttcg gttcgacgta cacggcgtag tcgtgctcga cgctcacggt
    18481 tacgggtgtc agggcgccgg gcacctccac cggaccgtcg acgtccagcg ggaggccagt
    18541 ccactcgcgc cactgggcga ggcttccgga aatggtcatg gacgccggac acacctgcag
    18601 cacctcgccg cctgccctgg cgtggacacg cagccagggg tcctcgggca gcccgtcagg
    18661 ccggcgcagc gcgacgtatt cggccagcgg cagctccggt cgccggtgct tgccgttggg
    18721 gcggaccgga acgaccaggt tgcggaaccc tttgccgcgc gcgtggtcga agagggcccg
    18781 aagggtgtgc ccggacaggt tccgcgcctg gtagccgggg atgacggcta cctccagcgc
    18841 gcacagcgtg gtgagcgccc ggccggcgta ggtgtccgac aggctctggc gcagcgcctc
    18901 gtcccagccg gtgtcgggca gtcggccggg gtcgccgtcc caggccagag gtacggaggc
    18961 ggcccgggcg acgacgcggt cgtcctcgtc gaccaatacg agttggtgct cggcgtggcg
    19021 gtcgaaggcc caatccacga ggagcgggtc ggggcggatg taggccggcc acgacgactc
    19081 catcgtgagc atcgcctctg cgaggtccgg cctcccggcg atgctgatca cacgcaggtc
    19141 gtggctggcg gtcgtgctgg acatgaggtc tctcccggtg acggagcgcg ggtgtggtgg
    19201 gcggggctca gtcggcgagc cgacgggcgg gcagtctccc ggtggccagc gggcggccct
    19261 cgtcgcgggc ggagagcagg ccgaagtact ggcgcctgga catcggctgc gcgcccagca
    19321 gccggacgtg gtcgccgtcg cgctggacgt cgacggcgag ccccccggcc tcggcgaagc
    19381 ggcgcgtcag gtcggcgacg gcggccttgc cggccccgct gcgcagcgtg aactgggagt
    19441 cggcgctgaa cacggcgccg acccgcacgc cgaggacgcc gccgatcagc tcgtcaccgt
    19501 cccagacctc gacgctgtgg gcgtggccga gttcgtgcag caggcacagg cccctcagca
    19561 ggtcgtcggt cagccagcgc tcggtgcggc ccgcacggca ctggcgggcc acccgctcga
    19621 agcagacgtc cgccgtcgtc gtccatccgg tctccttgcg tagctgccgg cgcagactgc
    19681 gctggatccg ggcctgctgg acgaggatga cgggccgcgg gtccggtgag caccacgcga
    19741 tcgagaaggg gtcgtcgtag ccgggtatca gcttcacccg cccggcagcg acatcggcct
    19801 cgtaggtgag ttcgttgacg atgcagtgct cggcggtttc agccggaaag gggtacagcc
    19861 cgtgccggta ggcggtgagc agggaccgcg ggccgaggtc gccgccgaag gcggccggtc
    19921 cctcggtggg ggcggccagg acgttcagag attcccaggg cgtctcggga cgagcctgtg
    19981 tcctgatgta cacgcccacc tcacaggaag tcgatggagg tcaagtaccg gatgtagcgg
    20041 tcgagcagat caccgtccac gggagggatc tcgatcccgc tgccgctcag cgcggcgcgg
    20101 acgttgtcct gggagaaggt gggaaacgtc gtttcgagat acatctcggc cacgctcatc
    20161 tcgcccgtgg agcatcggtc gatgaagagg ggagcgaacg gcgtcatggg atggtcgggc
    20221 tgttcgatcg ccgtcgacac gatgccttcg acccactctt cccacgggat ctcgcggatc
    20281 gcgtggccat gcgcgcgaag ccgctcggcg agcagggaga tgttcacctt ccctgggttg
    20341 gtcaggtggt agacctcccc cgagggcagt ctgctcgcgg cgatgtgcag caaagcggcc
    20401 gcgtagcagt cgaccggggt gtagtccagg gggagttcgg cgatgggcga cgtcccggta
    20461 tcgacgatga acttcttcat cgcgcacatc tcggtcgccg tgttccacgc ccccctcgcc
    20521 cggtcaccgg agatgtcggc ggcgcggtag atggtgaccg gcaggccctc cttcgccgcg
    20581 ttcctgagca gttcctcggc gacccacttg ctctcgacgt agccgacgga caaccggtcg
    20641 gagtgggcga gaggcgtctc ctcggtgatg tgccggactc cggcggtgcc gaacccggag
    20701 atcacggcca tggtggagac gtagtggacc gggatgttcc ggtagcggcc ggccatgcgg
    20761 atgatctccc gggtgccctc gacgttcgcc ggacgcatat gggagtaggg gtagatgaag
    20821 ttgaccagtc cgccagggtg gtgaatgacg tcgacgacct cggcgaggtg gtcgaactcc
    20881 tcctccgaga ggccgagaag cggtcgggcg aggtcgccgg ggacggcacg gatgcgtccg
    20941 gaggcgtggt acgcgtccag gccgtcgtcc aggtagtgcc gcgcgttgtc ccggatgcgc
    21001 tctcgcgcct ggtgggcgtc gtcggcccgc accaggcagt ggacggtggc ctcggtggtc
    21061 gtcagcagcc ggtgcaggag gtggatgccg aggaaaccgg tggctccggt gaggaagacg
    21121 tgggcaggat cggcccacgc cgtgggcggt gtcggcgagg actggatggg taccccgacg
    21181 gcggtgtcgg ccctgagggc ggcgtgggtc gcggtgtcgg tgctgagcgt gccggctcgg
    21241 gccgcttcga ccgccgacgc gaagccgcgc agggtggcgt cgtcgaggag aatccggatc
    21301 agcgggcgca cctgggtgat caggatgccg agcgaggccc gcaccttcgc gaggagttcg
    21361 gccgcgagaa tcgagttccc gccgcggtcg aagaagttgt cgccgggcgc gacggagtcg
    21421 atgccgagca cctggcacca caggcccgcg acagcgcgct cgaccagacg cgcggcggga
    21481 gcgtcgtcac cggtcgggga cgcgccgccc ggctcttgcg gctcgggcag cgcggcgagg
    21541 tcgatcttgc cgttggtcgt cgtcggcatc tcgtcgagct ggacgaacct ggccggaacc
    21601 atgtaggcgg gcaggtggtg ggcggcgaag gcgcgcagct cgcccgggtc gagccggtgc
    21661 ggcgcgcggt tcgcggtgaa gtaggcggcg atcaggggtt cgccccggtg gctgaaggcc
    21721 gtcaccgcga cgtcgtcgat gaactcgtgc gccgacagtg cggcctctat ctcggcgggc
    21781 tccacacgga atccgcggac cttgagttgc cggtcggccc gtcccacgac ttcgaggttg
    21841 ccttcggcag tccagccgcc gaggtcgccg gtccggtaca cgcgtgccga gtccgccgtc
    21901 gatccgggaa gggtgaggaa gcgcttctcg cccggcgcca tgccggccag gtagccctgt
    21961 gcgacgccgg gaccgccgat gtagatctct ccgtgccgcc cgggcgggac cggcttgagg
    22021 tcctggtcca gtacgtggac gacagtgtgc ggcagtggct gtccgaccgg tgccgggccc
    22081 tgtgcgggca gcacttccgg ggtgatgtcc atcgtgcatg acgtgatcgt cgtctcggtg
    22141 aggccgtagg cgttgaccag ccgggagccg ggcagcaggc gcagtgcggt acggcagtcc
    22201 tcggcgtgca ccgcgctgcc gcccacgatg gtgagccgta ccggcaactc gaccgggttc
    22261 cgggcgagtt cggcgaggaa ggcgcgccag tagggcgggg tcaggtccat gaccgtcaca
    22321 ccgagtgccg tgagccggcc gggcagttcg ctcggcgccc agttgtactc gggcaggacg
    22381 agtgtcgcgc cgttgagcag ggtgacgagg atctgctcga tggaggtgtc gaaggacagg
    22441 gcggcgaact gcagcacccg gtccttcggg ccgatgccgt accgctcgct cacgtgccgg
    22501 aagagatagc cgagcgaggc gtggcccacc ttcacggcct tgggagagcc ggaggagccc
    22561 gaggtgtaga tgacgtaggc ggtgtccgag gcctcgacgg cgacgggggg cgggtcgacg
    22621 ggtgatccgg cggcgaggtc ggcgtcggcc ctgaggggcc gcaccgggag agcggcgaac
    22681 cggtgttcgt ggtcggagcg cgtgatgacg agggcgcagt cggtcccctt gacgtaggcc
    22741 gagagccggt cgtcggggat cccgggctcc acggggaggt aggcggcgcc tgctttgagc
    22801 gtcgcgagga acgacacgat gaggtcgatg gaacgctcaa ggtggaccat gatcaccgat
    22861 tcgcgtccgg ccccgagagc ccgcaggcga tgagccaatc gatccgcgcg cttgtcgagt
    22921 tccgcgtagc tgatccggtg tccgtcgtgt tccaccgcag tcgcatcgcg ccggtccgcc
    22981 gccacggcgg cgaagcgatc atgtatgagc ggcttcccga tgatgtccat aagtcctctc
    23041 gtccaatgcg cgttgccaag aacgctgacc ggtcgtcagc ggcggaaagc gggcggtcaa
    23101 ggcttgaagg cgtgacggac ctgcatgtcg acgcatgaac tgggcccggt ggccgatcac
    23161 ggaaatcgat gggaagaaac cgctcggcac gcgggacagt tcattgctga tttgttctcc
    23221 ccgtctctga tggcgctcat gttggaattc cggcttcact ggaaagcgat tcgtcctgcg
    23281 agatgatcaa gccgattgtg gctgcttgat tggcgcagca accgagagaa ccctacgggg
    23341 gtagggcatg tcaacccggg caaaaggtgg tgaatcgcaa aggtgagggg tgagtaactg
    23401 gcgatatgga gagcctctga ttgcggagag atcgagtgat gagaggagaa ttaccgaatt
    23461 ttgcgcgttg tgctttcggc gacggctgtc atatacacgc gaatcggttt tctgaatgag
    23521 taccggactt tacgcagagc ggccgaaggc gtggaaggcc ggggtgagcg atgagatcgc
    23581 cccggccttc cgggcctcag atgcgcaggt tcctgcggga ccgggcagcc caccaggtcg
    23641 tcgggccgcg ggtgccccgg tgccgccgcg tgcgtggcct gcgccacggc ttcgagccgc
    23701 aggatgcccg gtaacacggt cgtgcggatg gtcgaagagc acggcattcg agaggtccgt
    23761 gcgcacctgg gagtgacgtg cggagcgggg catgcagcga gagcacacgg tcgccgtgcg
    23821 cctcggccca ccgggagccg ctctccggtt cgctttggcg cggtgtcagg cggagagcgg
    23881 gacggcgcgc cggaagccgc cgcggaagaa cggcagcccg tcccgggcgc cgccgtggct
    23941 cgctccgacc acctcgccga tgaagatcga gtgggtcccg aagtcgtagg cggtggacag
    24001 ttcgcactcc agccaggcca gcgagcccga cagcagcggc gcgccggtac gcggccccgg
    24061 ggaccagtcg acgtcggcga actgcccggg ccccagcggg cgcgtcttgt ccgcgaagaa
    24121 acggaccagg ccttcctggc cggcctccat gatggacacc ccgaaatgcc ccgcggtctt
    24181 gatggccttg tgcatcacag cgctccggtc gacacagcac agcacagcac ggacggcggg
    24241 tcgagcggga cagaggtgaa cgcgttcgcg gtcattccgt ggatgtgttc tccgccggtg
    24301 gacagaaccg tcactccggt gaatgtcact cccatcgggt gtcccatgga tgtggaacct
    24361 acggggcgcg cagaacgacc tgggcatcgt gcggtaatcg gccgctcgcg ggcatcgagg
    24421 ccggtaactg gtgagtctcg gagcggaaaa ccggagaatt tcctgtcagt gattgttcga
    24481 cgagcgggtc tggttagcct cggtgcgtgg cggttcgacg atcgcgccgt gcagatgtgc
    24541 cttcgcgaga aaggcgggcg tcctggcgaa aggcgcggtg aggccgtcgg tgccgtcaga
    24601 tccgtccatt tcgtatggag gaaccctcgt gcgcaaggtg ctcatcgcca accgtggcga
    24661 aatcgctgtc cgcgtggccc gggcctgccg ggacgccggg atcgcgagcg tggccgtgta
    24721 cgccgacccg gaccgggacg ctctgcacgt ccgcgccgcg gatgaggcgt tcgccctggg
    24781 tggtgacacc cccgcgagca gctacctcga catcgacaag gtgctgaagg ccgcgcggga
    24841 gtcgggggcg gatgcgatcc atcccggcta cggcttcctc tccgagaacg ccgacttcgc
    24901 gcaggcggtc ctggacgcgg gcctgatctg gatcggcccg cccccgcagg ccatccgcga
    24961 cctgggcgac aaggtggcgg cccggcacat cgcgcagcgc gcgggcgccc cgctcgtcgc
    25021 gggtacgccg gacccggtgt ccggtgccga agaggtcgtc gccttcgccg agcagcacgg
    25081 gctgccgatc gcgatcaagg ccgcgttcgg cgggggtggg cgcggtctga aggtggcgcg
    25141 gacgctggag gaagtgccgg agctgtacga ctccgccgtc cgcgaggcgg tggcggcctt
    25201 cgggcgcggt gagtgcttcg tcgagcggta cctggacaag ccgcggcacg tggagacgca
    25261 gtgcctcgcc gaccagcacg gcaacgtggt cgtcgtctcg acgcgtgact gctcgctgca
    25321 gcgccgtcac cagaagctgg tcgaggaggc ccccgccccg ttcctgacgc aggaacagac
    25381 cgccgagctg taccgcgcgt cgaaggcgat ccttcgcgaa gcgggttatg tcggcgccgg
    25441 cacggtggag ttcctggtcg gcaacgacgg cacggtctcc ttcctggagg tcaacacccg
    25501 tctgcaggtg gagcacccgg tcaccgaaga ggtcgccggc atcgatctgg tgcgggagat
    25561 gttccgcatc gccgacggtg acaagctcgg ctacgacgac cccgaactgc ggggccattc
    25621 cttcgagttc cgcatcaacg gcgaggaccc gggccgccac ttcctcccgg cgccgggcac
    25681 ggtcacgacc ttcgccacgc cctccggccc cggcgtccgc ctggacgcgg gcgtggagtc
    25741 gggcagcgtg atcggcccgg cctgggactc gctgctggcc aagctgatcg tgacggggcg
    25801 cacccgcaag gaggcgttgc agcgcgccgc ccgagccctg gaggagttcc aggtcgaggg
    25861 tatggccacg gcgatcccgt tccaccgcgc ggtggtcaag gacgccgcct tcgccccgga
    25921 agtccacggc caggacgggc ctttcacggt ccacacgcgc tggatcgaga ccgagttcgt
    25981 caacgagatc aagcccttcg ccgcccccgc cgacgccacg gaggcggagg aggagtcggg
    26041 ccgcgagacg gtcgtagtcg aggtcagcgg caagcgcctg gaggtctccc tgcccgcctc
    26101 gctgggcatg tccctggccc gcacgggcct ggcggcgggc gccaagccca agcgccgggc
    26161 agcgaagaag tccggccccg tcgcctccgg agacaccctc gcctccccga tgcagggcac
    26221 catcgtcaag gtcgccgtcg aggagggcca ggaggtcaag gagggcgacc tggtcgtcgt
    26281 cctggaggcc atgaagatgg aacagccgct gaacgcccac aaagcaggcg tgatcaaggg
    26341 cttgacggcc gaagtcggcg catcgctgac ctccggtgcg gccatctgcg agatcaaaga
    26401 ctgaagtact tcagtcccga cggcagcgca tgtgctcccc acacgattcc cctgtggagg
    26461 tgcgccggcc tgttcctacc gatctattcg tgacctaccc gatgaatttg agaagggttc
    26521 aggacggcga acggagctgg acctaccgcc agttgcacga gatcgccggt ggcctggcgg
    26581 ttgcgctgca ttctgtgggc gcggatcccg cccgtcccgt ggcggtgctg ctggagcgtt
    26641 cggtgtggat ggtggcggcc gcgctggcgg tggtgcggac gggctcgtcg tacgtgccgc
    26701 tggatccgga gacgccggcc gctcgtctgg agtcgatcgt cgaggacgcc gagccggcgg
    26761 cgatgatcac gtccagatcg ctggcggggc gggtgcccga cggggtaccg gtggtgtacg
    26821 tggacgatcc gctgccggct gccgaggact tcacgtccgc ggcggtcggc cgggacacgc
    26881 gggcgtacat catcttcacg tcggggacga cgggtcggcc gaagggcgtg caggtctcgc
    26941 acggcaatct gctgagcctt ctcgtggcga gccaggaggt gtacgacttc ggtccgaacg
    27001 acgtgtggac gctgttccac tcgttcgcct tcgacttctc ggtgtgggag ggggcgcccc
    27061 cctgcacggc ggccgggtgg tcgtcgtacc ggcgcagacg gcgaaggatt cggcggcgtt
    27121 caggcggctg ctgcgcgacg agcggatcac ggtcctgtgc cagaccccga ccgccttcca
    27181 ccacctcgtc gcggaggaga cccgcttcgc cgaccggctg tcactgcgct gggtgatctt
    27241 cggcggggag accctgtact tctcggacct ggtgccgtgg ttcgcgaagt acggcgacga
    27301 ctccccccgc ctgatcaacc actacggcat caccgagacg acggtgcact cctccttcca
    27361 ccgcgtcacc tcggaccagc tcggccagga cgagtcgctg atcggccgcc ctctcgccgg
    27421 caccgggttc ctgctgctgg acgactctct ggcagccgtg tccgagggcg agatcggcga
    27481 gctcgtggtg accgggtcgg ctgtcagcct cggctacctc aagcgccccg agctcaaccg
    27541 ggaccgccgt gacgaacgtg gcatcccgtt cgtctcggcc gccgaggaac gcgacctcta
    27601 cttcgccgtc ggctacgccc aggcgaccga ccggctctgg cagatggacg cgcttcggcg
    27661 ccgggcccgg ggacggctgg ccgagatctt cggcgccgcc gtggtcgacg aggacgtgcg
    27721 ggcgcggaag ctcgggatcg accgggttcg ccggcgcctc cgaggcgctg ctctccgacg
    27781 gtcaccgggc caacctggtg gcgttcggcg ccggggtcga cgcggccgta cggcggatgc
    27841 gacggcgcgg cgggctccca gtggagttcc tgctgctgcg ctaccgtccc gagccctgga
    27901 caccgcggga ctcgatcgcc atcgtcaaac accttgggtt cgacctcggc cggaacctcg
    27961 ccaacgaggc gttccgcgcc aggctggccc gggaacaccc cgagtacgtg tcggctttcg
    28021 cgacacccaa gtatcccgcc gacggagcgg tgaccatccg cacggccctg ccgggaaaga
    28081 cgccggccag ggtggacacc cccgctccgt ccggtctgcc gcgggcctcg agggcctggc
    28141 tcgacgcgct gctgtgcggt gagcatcccc tgggctccaa cgcgtgggcc gtctcgggct
    28201 cccgcacggc ctccgggaac ccgctgctgg ccaacgatcc gcacatcgtc ctcacccagc
    28261 ccagcctctg gtaccagatg ggcctgcggc tggacgacga ggcggacgac gcggtcggct
    28321 acggggtcac cgtccctggc ctgccgggtc tgatcgccgg tgccaaccgt catctggcct
    28381 ggggcatcac caactccacc gtggacaccc aggacctgtg cacgctgccg gccacggatc
    28441 cggatgaggc gtggaccgag gagagcgtga tcaccgtgcg cggcgcggag cccgttcgag
    28501 tgcgggcggc gggcggcgcg cgccacgtcg aactggaccc tcccggctcg gacggcgacg
    28561 gccgctacgg cctgttctgg agcggcctgg tgccctccgc ggagatcgag gcgtgtcagc
    28621 ggatgtggcg cgcgcgtgac tacccgcaac tccgggacgc cctgcggacg ttcggagtgc
    28681 cggtgctcaa cctggtggtc gcgtgccagg acggcacgat cgccctgaag acggcgggga
    28741 acgtcccggc ccgggagccg ggcagcagcg ggcgggtgcc ggccggacac gccgaagtcg
    28801 cccgctcctg ggcggagttc ctcgccttcg acgacctgcc agaggtggtc gacccgcccg
    28861 agggatacat cgtctccgcc aaccaccggc tgctgcccgc cgacgccccg ctcgacgtgg
    28921 gggtggactg gctgccgccc taccgggcgg agcggatcga ggaactgatc accacggacg
    28981 cggtcgtcac cgcggccgcg tgcgcccgct ggcagtccga cgtcctggac gggcgggccc
    29041 gccacgtgct ccccaccctt cttgccgcgc tggacggaca gtctttggaa acaccgctcg
    29101 ccgtcacctg ccgtcgcctc ctcgaagaat gggacggaca cgaccacggt cagatggcgg
    29161 cgcccctggt gttcttccgg ctcatgcagg tgctcacgga gcactggatc ggcgaccggc
    29221 tggggcagga actggccgcc gccatgccgg acgccgcact ccaggttgat catctgatgc
    29281 tcactccgga cgccagggcg gcactcggcg accaggagga actgccggcc gcggtgtgcc
    29341 gtgcgctgac cgaaacggca cggcggatcg ccgcggaact gggcgaggac ccgtcgcggt
    29401 ggcggtacga ccgagtacac aggaccaccg accagcaccc gctggcgaag gccgtcccca
    29461 tcctcgcccc gctcttcggc acctcctcga ccccggtcgg cggcagttcc cacacggtcg
    29521 gcctgacctc gtccgccccc tcgggcgccg tggtggacgg agcgccctgg cgcttcgtag
    29581 ccgaactgtc cacctccggc ctgcagttgt gggacgtcct gcgtcacggc gcctccggca
    29641 acccgatctc cccccactac gacgaccaga ccccggccca caccgaagga cggcactacc
    29701 gcgtgcccct gctgccctcc ccggacaccg caccgaacct gcttcgcctc cgggcccggt
    29761 gaccactgat cttgcgtgct agccccgtcc tcagggcggg gctcgggcct gttgcgaacg
    29821 tggcgtcgtc gcctgaaggg cggccgcgcg cccgccgcgg cagcggctga tgggagtgtc
    29881 ggtgtgtgct ctccgcgtgc cgcccggacg ccctcgtacg gggtgtactc gggctttcgg
    29941 gcggtgcggc gagtgggggc acctcccacg cccttgaggc agtgggggag cgtgccgggc
    30001 gtcgcgcggc aggcgccact ttcgcaacag gcgctagccg cttctctgga ccgctctgac
    30061 gcttgccagc cccccctcaa cgctccacgc gtggccgcgg agccatgggg atgtcgtgcg
    30121 ggtcggctcc gcgagggcgg gccgtcgcgg tgtccggtca ggatctggtt ccatcgggcc
    30181 gcgggacctc gcccgtccgg ccgtcacgtg tttacgggac gtcttgcacc gtacacgtat
    30241 tcacgggatg ggagattccg ggtgtcccgc aaggattggt gagtcggcaa tcaaacagac
    30301 cgagatcacg ccctctccgt tgagggaagg aaagaagtcc ggtgactcag caatccagtt
    30361 ccgcacctgg aatcgcgacc gttgtcccga cgaccgggcc gcacaccgct cgcaaagccg
    30421 gtctgatcgc cggaatcatc ctcgtctccc tcaacctccg tccggcgatc accagtctgg
    30481 gaccgctgct cccgcaaatt gaggaggacc tcgggctctc cgggaccgga gccggactgc
    30541 tcaccatgct gccggtgctg tgcctgggag tcttcgcagg gctggggccc acgctgcgtc
    30601 accgcttcgg cgaggaccgg gtgctgctcg gctgcctgcc cgtcctgctg ggcgggatcc
    30661 tgctgcggct gctcgacccg acggctctgc tgtacgtcgg tacagtggtc gtgggtggcg
    30721 cgatcgccgt cgccaacgtc gtcctgccca gcctgatcaa acgtgagttc cccgaccgcg
    30781 tccccttgat gatggccacc tacaccatgg ccctcacgtt cggcggcgcc gccgcggccg
    30841 gtgccgtcat cccgctccag agcgtcgtgg acaccgactg gcgcgggtcc ctcggactgc
    30901 tcgccgtgcc ggtcgtcgtg ggtgtcgtcg cctggttgcc gttcggtctg cgccgcgtgc
    30961 ggacgcgtgc ggacgggcgc gcgcccatcg gtccgctgct gcggaaccgg ctggcctggc
    31021 tggtcaccgc cttcgtcggc ctggaggcgc tcctggccta cgtcatcttc ggctggctgc
    31081 cggcgatctg cgtcagccgc ggcatgagcg aggccgcggc gggatacatg atgtccgcga
    31141 tcaccttcct ccaggccgcc ggatccatgg tcgtcccctt cttcatcgac cgcggcggcc
    31201 gggggcagcg cggcttctgc gtcgtcgtcg cactgggcac cgcggtggga ctcgtcggca
    31261 tcgtcgtcgc tccgctgtgg acgatctggc tgtgggcgct ggtcctcggc atcatcggcg
    31321 gcgcggcgtt cagcctggcg ctgacgctca tcggtctgcg cgcgggcgac ggggacaccg
    31381 ccgccggcct gtcgagcatg tcgcagggcg tcggctacgc gctggctgcc gcggggccgt
    31441 tcggcgtcgg ggcgctgtac cagctttccg gtggctgggg cgtgccgctc gcggtgctgg
    31501 tggcgctctg cgtcctcatg gccgtgatcg gggtgggcgc cggccgcgac gcgaccctgt
    31561 cccgcgagat gtgaactcgc gcggcgggcg gtccggctcc gcccgccgct tcggcccctc
    31621 cccaacaccg cacgccttca cttcttcacg ctccttcgac cgtgctccgt ccagccgcgc
    31681 gccgcgccgc cccggtccgg ggaatcgtgc tgcccggcac ccgcctggta cccgtccgat
    31741 gggaaagaga agatgagagc agtagattta cccgcccccg aggtgaccga cccggctgat
    31801 cccgtggccg tcgtgcaccg gcacctcatc cacgacggcg tgtccgccgg ccgacgaaca
    31861 cccgtggtgc accgtcggca cggggcccgg atcgagaccc gggacggcag agtcctgctg
    31921 gacgccgcga gcggcggctt cggcggatcc cacgcccgag tccgggccgc gatcgccgac
    31981 caggcccgcc gcgtggccct ctccagccgg atcctggtca gccggccact cgccggggcg
    32041 gtggcggcgc tcgcggagtt ctgccccggt ccgctgtccg tctcctacct ctgcaacagc
    32101 ggggacgagg ccctcgactc ggccctgaag ctggccaagg gcacccatcc ccgtcgcccg
    32161 tacgtcctcg gcatccgcgg cgaggacttc ggcaccctca gccacggcca ggcgctcggc
    32221 caggggcgtg ccctgctgcc cggggccccg ttcctgccgc gcacggtgtc cgcggaggca
    32281 cccgaggaac tgctggagca ggtcgacgag tccgtctcgg cggtcgtgat cgctcccgcg
    32341 gcgcccggtc ggccgctcgg ccgactgccc ctggactggt gggtggcgct gcgggagcgc
    32401 tgccaccgca cggacacgct gctcgtcctc gacgagcggc acaccggtcc ggcccggctc
    32461 ggccgcgatc tcggcgtcgg tgcgctgggg atgttccccg acgcgctgat cctcggcgac
    32521 accctgggag ccgacgccgt acccgtggga gtggccgtgt tgacgccggc cgcctaccgg
    32581 cgcgtctacg gcggccgcaa tcccagcctg cacggctcca ccttcggcgc caaccccctg
    32641 tccgccgccg ccgtgagcgc ggtcctcgac gccgtcgtcg gcgacgatct cgcggcgcgg
    32701 caacgggatt tcgagcacgc ggcgctccgg ctgcgcgacg aactggccga cccggccggc
    32761 gcgttcgggg aactgcacgc ggacggctcc ctgttgtggg tccgcgcccg cggcgccgcg
    32821 gcggcacgcc gactggccgg cgaactggcc gaccgcggcg tgctggtgcg cgaccctgtg
    32881 gccgacgtgg tcaccctgac cccgccgctc acggcagaac gcgaggacat cgaccagatc
    32941 ctgcagcggc tcgccgagtc actgaaggcc ctcgatgccg aggaggccgg acgatgagtg
    33001 cctcgaccgc ggtggctgcc ctcgaccggc agcaggtcct caccacgctg ggccgccact
    33061 ggaatcccac cgcggccctg atgctggccg cgaccggacg ccagctcgag tcgcacgccc
    33121 gaggtacgga ggtgttcggc gaggacggct cacgcgccct ggacttcgcc ggcagctatg
    33181 gcgtcttcct cgtcggtcac cagaacgacg cggtccgcgc cgccgtcctg gacgccctgg
    33241 acacggcgcc gtcgctggta ccggggaccg tgcatcctgc gacggccgac ctgttcggcc
    33301 tgctcacgga gatcctgcct gccggcctcg accgcttcgc gctcggctgc tccggggccg
    33361 agatctccga aatcgccttg cgcgccgcct acttggcccg gccggagcgg cgcaggatcg
    33421 tgatcgtcga gggcggctac cacggcaaga ccctcggtgc gctcaccgtg ctcggccagc
    33481 gggagcaccg ggacgacttc gcccccgccg accgcgatct ggtgatcgtg ccgccgggcg
    33541 acgcgggagc cgtgcgcgag gccgtcgcgg gccgggacgt ggccgccgtc ttcgtcgaac
    33601 cggtgctcgg cggcgcgtac ttgagggtgc cgcccgcgga cttcatgccg gacgtggccc
    33661 gggcctgtcg gcagaccggc acgctgctcg tcgccgacga gatccagacg ggcttcggcc
    33721 gtaccggcag gatgttcgcc atcgagcact ccggtgtcgt ccccgacatc atgctcctgt
    33781 ccaaggcgct gaccggaggc ttcgtcccgg tcgcggtggt cgccatgagt gaggaggtac
    33841 tctccgacgc ccggcggtcc ccgcagtggt accccggggt gctggacggc accggaggct
    33901 ccgcgctgtc ggtggcggcg gccgctgcga cgatccgtgt ggtgcgcgac cagaacctgc
    33961 ccgagcgcgc cgaaaccgtc ggccgggcgc tgcgcgaagg tctccaccgg gccgtgcgcg
    34021 agcatccgcg gcacctcgtc gacgcccccg gcatcggcct gatgaccggg ctgcgcaccc
    34081 ggaacccgtc ggtggagaac ctgatctcca tgcagatggc ggcgcgtggc atccacctcg
    34141 gtcactcgct caacgagcag atggaccagc ccgtgctgag gttctatccg ccgctgaccg
    34201 tctccgccgc cgagatcgag cgcgtgctgg tcgcgctcga cgcgtcgctc gactggctcg
    34261 acaggcgccc ggcatggctc atgcggcgca tcacgtggct gctgcgccgc cagtaccggc
    34321 tgcctccgac cctcgtcctc aagctgatgc actccgacct cgaagtgaat tggtgacctt
    34381 catggacata gcgatcgcag agtccggtac gcccgagtgg tacgaggccc ggatcttcgc
    34441 ccaggacagc tatcgcagga cctatggcgc gacgaccgcg cccagccccg accgcttcgt
    34501 gaccgtgcgc gagtcgccga ggggcgcgat cgtcgcctgc gccggcctca gcggcccggg
    34561 gacggacggc ttcttctccg agaactacct cggctgcccc gtcgagcggg cgctggcgcc
    34621 ggtggcgggg gacgtaccgg agcgtggcga ggtggtggaa gtgggaccgc tggccggggc
    34681 cgggggtgcg ggcggggagt tgatccggct gatgccggtc atcgcctggt gccaggggaa
    34741 acgtttcatc ttggccaccg tcacggaccg ggtcgaagag gccatggcgc gtgcgggagt
    34801 gccgttcgtg ccgctgcgac aggcgagtgc ggactggatg gacgaggagg ccagaagtgg
    34861 gtggggctcg tactacgagc ggtcaccgac cacgggcgtg gtgccgctcg acagcatcgg
    34921 gcggctgatc aacagcctga ccgggcgcta cacgttcgta gagctcgctg tacagaccct
    34981 cgtcggcacg tcgcgggagg tgtccggtgc gcacgcttga acagagtctc atggacctgg
    35041 ccgaggacga acgcccgctg gtcgaggtgc ttgcccccga cggctcggtg gcccgttcgt
    35101 actcctaccg gcatgtcgtg cgggccgcgg cggaactggc ccgaaccctg cgcgagcggc
    35161 ccgtccggga ccgcggagcg cgcggggccg gcgaccccac ggatcccggc cagctccagg
    35221 tgggtgtggt gacggccaac gggccggagt tcctggtggc cgacttcgcg gtgctcggcg
    35281 cgcgcggcgt cgaagtgccg gtgccgctcg cgttcacggc cgagcaggcg gcggccatgc
    35341 tcgaggacat cgacatctgc ctcgccgacg aggcgggcgc gcggcgcctg cgggaatggg
    35401 gagcggagaa ggtactgccg cccggggttc cgctgcaggt gctcgacctc gagcgaccgg
    35461 cggcgagtga gaccgccgcc ccgctgtttc cccgagccga ggccaccgcc cggctgtgca
    35521 agatcatcca cacctctggg accacctcgc ggcccaaggg cgtgtgcatc cgcgagagcg
    35581 cgctggagga gctgatcggc tcactgcgcg cggcgatgcc accccgcgcg taccgccgct
    35641 acctctccct ggtgcccctc agcctgctca tcgagcaggt cacagccgtc tacctcgtgg
    35701 tgtgcgacgc cggcaccgtc gtcctgctgc cgccggaggt gccgctggtg gggacctcct
    35761 cgttcgcccc gcaggccgtg ctgcctcacg tccgggcggc ccggcccagc gcgctcgtca
    35821 tcacccccgc tctggccgag gccatggcgt cccgggccgc cgaggcgcgg gcgtccggac
    35881 gcgacccggt gaccgacctg ttcgggcgcg ccgaggcccc gttggtgtgc tgcggcgggg
    35941 caccggtcga cgccgacatg ctgcgcgccc tcgacgacca cggcatagcc gtccatgagg
    36001 gctacgggct gagcgagaac agctccgtgg tcagctggaa caccccggcc gcccgcaggg
    36061 tcggcagcgt cggccgcccg ctgcgccacg tccgtgtgcg gacggcgccc gacggcgaac
    36121 tgctcgtcaa gagcacgtcg ctgttcgccg gctacaaggg cggtgacgac ccgtcgggct
    36181 gcgacgtgga cgaggagggc tggctgcaca ccggcgacct ggccgtcatc gaggacggct
    36241 tcgtctggat caggggacgc aagaagagcg tcatcatcac ctcggcgggg cggaacgtgg
    36301 cgcccgagtg ggtcgaggcc cagtaccgct cccatcccgc cgtcctggcc gtcgcggtgg
    36361 tcggcgacgg tctgcccgcc ttgcacggac tgttcctcgt cgacccgcgg gtccggcccg
    36421 aggcggtgcg ggccgagctc gactcgctgg gccacgaaag gctttcacag gtggagcggg
    36481 tcgaggtggc ccacgtggtg cctgccgacg agagcctcca tgccgagttc ttcaccgtca
    36541 ccggacgacc gcgccgctcc gctgtgcagg cggccatagc ggcgggccgc ttcgcatgac
    36601 atcccgctcg ccgcgcacgg tgccggccac cccgcggcgc cgcgcatccg accgcgcagg
    36661 cggtccacat ccggaggaga aaccatgatc gaccttgcac gcctcacccc gtacggctcg
    36721 ggcaccggtc tgctcgtcga gccgaggagc gcggacacga ccctggggag cctcgcgccc
    36781 gagcaggtcg tgtgtgtgct gcgcgacgcc ggattcctgc tgttgcgcgg tttccggccg
    36841 gacctcgaac agttctcggc gttcgtcgcg acccactccg aacgggtcac cctcgacccg
    36901 gcccgttcgt ttcacggcgg ctccaccgcg cagttggtgg atgccgggta cgacgcggtc
    36961 ggcctccatc tggagaacgg caacagcccg tttgccccga ccctgacctg gttcttctgc
    37021 gagaaggccg cctcgtcggg ctcgcagacg acggtgtgcg acggctaccg ggtctgggac
    37081 gcgctcagcg acgaggcccg cggtctgttc cggcagcacg agatcgtcta cagccggcgg
    37141 gtcgaggagg cgcggtggaa ggccttcgca gccttccacc tgggcacctc cgacgcggcc
    37201 tcggtgacgg tcgagcagct gcaggaactg accagcggtc ccggcgagac ggtcatcgaa
    37261 cccctgcagg acggagcgat ccactacgcc taccgcgttc ccgcggcgca cgagacgctg
    37321 ttcgacaccc ggccggcctt cgccaacagc atcctgggtc cctcgaacca ctacgagaag
    37381 cctcgcatca cgttcgccga cggccgggac atccccgtcc acatcctcaa ggagatcgag
    37441 agcgtcaccg aggagctgac cgaggatctg gactgggccg acggagatgt cgccctgatc
    37501 gacaacaccc gggtcatgca cggccgccgt gccatcaccg atcccgaccg caccatctac
    37561 aacgcgcaga gcgatctgga cagggggctg ctgcccgcct gaccgggcac cgggtgacgg
    37621 ggtcctgccg tcaattccca tcgtccgtcc gaagggcggg ccccggcggc gatgggcgtc
    37681 ggcgatcgac gcagcgcggc agatgcgcgt gccgggcagg aacgtgacga cagggcctgg
    37741 ggccgccggg acgattccgg cggccccgct cgtcgtgggg gcgtcagttc gcgccgcggt
    37801 ccgtccacag cgcctcccgg accggctcca gcagcgaacg cagcagtacg ccgttgcgct
    37861 cgccgccgat cactctgacc gcgggacgct cccggcggtg ctgcggccac gcgtccgacg
    37921 ccgacccggt ccgaacgaac gaaccccaca ggcgccgcac ttcggcgcgc agcccggaca
    37981 ggtccgccgg ttccgcatcg gcgaacagcg gggcacggcg cgcctcgggg cggcccagca
    38041 aaaacgggat ctccaggcag tgacaggcgc gcagcgccga gtaccggccg ggcacctccc
    38101 agtcgaagcg gaacagtctg acggccgctc cgcgttcttg gaccaggtcg ccgaactcct
    38161 gcgtcggcgc ggcgaagaag gcgtccgtct tcagctcctc gaacgcggcc ggccggtccg
    38221 ccgggccgga ggtgtagagc cgcagcgcct cctcggcccg gtcgccgaac tgcccggcga
    38281 actcctcggc gacctcctcg cgcgtcatcg cggcgagtga ggcgtccatc ccgtaccaca
    38341 gggcgcactc gtgccgtgtg gtgcccgcca gcacgtccag cccgtgcagc gggggcgagg
    38401 accgcagggc gcccagcaga tcgggcccca cgacggtgcc gtcggcgacg agctggaacg
    38461 gcggtcgcac gtctccgcgc gcccgggggc gggcgaggat ctgccgctgg gcgaggagga
    38521 tccgctcact gggcaccgtc cgcagggcct ggatcccgtc ggcgttcccg tcggccgaca
    38581 gcgctgccag caaggcgtcg gcggtgcggg ccgcctcggc gcgcgagagg ggaggcatgc
    38641 caaggggcgc gctgtgcagg gcggcgcgcc ggaacagcgg gcggacctgg ggcagcgcca
    38701 gcagcgccgc aagcgcctga ccgccggccg actggccgat cacggtgatg cggtgcgggt
    38761 cgccgccgaa ggcgtggatc tcgcgcctga cccagcgcag cgccatgatc tggtcgagca
    38821 ggccggcgtt ggtgacatgg cccgattccc cggtcgcacg gaacgtgagg gaggtgcccg
    38881 ccccctcgat cgcggccggc tccgcccagg agggggagag gaaacccagc gcccccagac
    38941 ggtagttgac caggacgacg acgatctcct cctgcgccgc cagctcggcc ccgtcgtagc
    39001 ggggcaggtc ggcgccgccg gtgaggaaac tgccgcccgg cagccagacg agcaccggat
    39061 acggcccacg accggtgagg ggcgcccaca cgttcaccgt cagacaggcc tccgtctggt
    39121 ccggtcccac cgggtcaccc atcagggccg cgaagggcga gggcagttgc gggggcaccg
    39181 tgccgacggg gccgtcggtg cgcaggggcg aggaccagcc ggcgtgcggg cggggcgcgg
    39241 cgaaccggta cgggcccacg ggaggcgcga cgtacggcac gccgcggaag gccgccacgc
    39301 tccgctccgg tccctcccgc ctgccgatga caggtccgcc cgatacctct gcctcgacgg
    39361 actcgattgc ctcgatggcc gtcgtcgccg ggccgggatc agcggggtgc atggattctc
    39421 ttctccgtat ccgtggggga atcctgggga ctcacttcgg gctgtgtgcc gggacctggc
    39481 ccgaggtgcc gtgcgccagc acgtaacggg ccagctcgac ccggcgcgac acgcccagct
    39541 tggcgaaggc cctgcgcaga tgggagtcga ccgtgtgcgc cgagacggcg agccgctggg
    39601 cggtctcccg gttcgtcagg ccctccgcca ccagccgcac cacccggatc tccgaggggg
    39661 tgaggctgtc ccagtcggca ctcgtgtgcg ccgggtcctg cgcggcgggc cgggcggccg
    39721 gtgcggggga accgggcagt gcctggacac cgtcggtcgc ggccgcttcg gagatccgtc
    39781 cctgcgcgga ccgcagccgg cggcggacgc gctcggcgcc gagtccggcg ccgctcgcca
    39841 cgtagacgcg ctgcgcctcc tgcagcatct ccgtggcccg tacgaggtcg ccctgcgcct
    39901 gcgtgacggc tgccgcgtct tccagggcgg aggccagcgc gaggggatgc gacccggtac
    39961 ggaagacccg cacggcgcgg tgcagcgggg cggccaggcc gcgatacagc ccgtgggcgt
    40021 gcagggcggc gccgaccagc ggcgttacac ctgggttgcg ccgggcgagg cggcgggcca
    40081 cggcgaccgc ttccgcggcc cgctcgccgg ctccggcgcg cagcgcgatg cggaccatgt
    40141 ggggcaggat catcgggtcc gcggtgagga accacaggtg gagatcgagg gcggaccaca
    40201 ccgtccccag ctgccgcatc gccgaccccg ggtcccctgc cgcatcgagg cgcagcgcgg
    40261 tgacgaacgc gtacagggtc ccggtgagcc ccggaagggc ggtgtgcgcg gtggacgaca
    40321 acgcggcgac gtgcccggcg gccgtctcca ggtccccccg taccgtcgtg accagggcga
    40381 gcacccccag caggaacgta cgcgcggcgg ggtccgccag ccgagcggag gcctccagac
    40441 cggcgtgcgc ctcacgtgcc gcctcctcca gccgtcccga gtgccacagc tgcagcgact
    40501 tcgcgatatg ccaccgcggc gccgtccaca cgcggtcccc ggcgcccgca ccgtcgcgcc
    40561 acgcctccag gacctccgcg gcatccagcg gacgcccggc caggcacagt gtgagagaca
    40621 gccacaaaga gccccagccg agactccgtt gtgtatcgac cggcccgtgc gccacggctt
    40681 cgccggccag ccgcagcgac tcggcgatgt caccggtgtg ccgggcgcac aggctcagca
    40741 cggccgtgcc gaggacgacc gaggcctggt ctcccgctcg tcgggcgagg gacaccgcgg
    40801 tccagctcag cgccgcggcc cggcccgggt cgcccgcgga gtacgccagc agacaccggg
    40861 cctccagcac catgagccag gcctggtggc tgaccggcgg acgggcgccc ttccgggccc
    40921 gccgcaggtg ccgcagggcg tggcgggccc cgctcagctg cagcaggacc tcgaggagtt
    40981 cggcgaacgc ctcggcctcg gcctcggtct cccaccccgc cgcggccagc gcggcgtcga
    41041 gcagatggcg tgcctcggcg gttcgccccg cggtgaggaa gagctgcacc gccgtggtga
    41101 cgggggcggc cgagagcggt tcgtacagac gcaggcgctc cagcagggcg cgggcgagtt
    41161 cttcctgctc ccgcgtcgga acggactcgt cgttccgctc cagccacttc agccgggcca
    41221 cgccctcctc caggtcctcc tcggccccgg ccaggatcag atgcgcgagg gtctccgggc
    41281 agggccgccc ctccgacacg cacaggcgag ccgcctccga gtgcagggcc cggcgcacgg
    41341 ggccgaggag gctgccgtag acggccaggt ggacgagtgg cgaacggtgg cggaaggcga
    41401 cgccgtcgtc ctccagcagg ccggccgcgg cggcctcctg agccgctgtc gccagttcca
    41461 tggtcgaacg gccggtcagg gccgccgcct gccgtagcga gaactgcctc cccaggaccg
    41521 ccccgacctg caacaggtca tgggtctgct gggagaggcc ggagacgacg ggggccgtcg
    41581 ccctgccgag cccggccggc aggtgtctgc cgaccacccg caccgtaccg tcctcctcgg
    41641 agcggacgcg cccttcctcg cgcagcagtt ggacgaggca gtcgacgagg aaggggctgc
    41701 cgcccgccgc gctcgtgagc cggcgcacgt cctcgggccg tgcgcagccg agcagccggg
    41761 caccgagttc cgcggcggcc gcctcgtcga ccggggacag ccgtacgacc tcggcgtgcg
    41821 aggtcaggag gcggtcgagg gctccgcgcg cggggcgtgc gacggggaaa tcggcgtagc
    41881 tcgccagcca cagggcgggt gcgtcggcga gccggggcag cagcgtctcc agggcggcga
    41941 cggtcaactc gtccgcccac tgcaggtcgt ccaggacgat caccatgggg gagtgggcgg
    42001 cccgctgctc gatgagccgg cgcaacaggt cgatgagcct gccccaatga gtgggccggt
    42061 cggccagggc ggccagcgac tccgcctgga cggggttgat gacgggccgc ggccccgccc
    42121 tcagtaccgc gagcagcggg gccatggcgg aatgccggtc cagccgcgcc acccgggcac
    42181 tcgacacggc catgccgcgc cgctcggcct cctcggccgc cgtgtgcagc agcagggact
    42241 tgcccgagcc gaactggccg tggaacacca ggaaggcgcc acggcccgcc gccgtcgcct
    42301 cgaacgcgga ccgcagcacg gccagttcgc ggtcgcgtcc cacgagacgc tggtgtcccg
    42361 atcgtggcat gaagcgcctc ctccctgtct cacggcctcc gtgtgaaccc ccggaccgac
    42421 gcgtgtgtgc cgagagaccg ccgggtgacg gtgtcggcgt cggaccggtc acagcgaccg
    42481 gccctgggcg gccttgcgca ccgccagcag cccctccaac gcgtgcaggc tcgtccgtac
    42541 gacgtgtcgt gccgcggtcg ccgccgcctc ggcgtcctgc tcctggatcg cctggaccag
    42601 cgcctcgtgc gcctcgatgc cgcactccag ttgcgtgtcc tcgccgccga acaggtcgag
    42661 gctctcctgc agccgcttga cgaagaagcg gtagcactcg gtgagtgtca cgttgtgcgc
    42721 cgcctggacg acggcgagat gaagcgcggc gtcccgcttg ccgaactcgg tcggctcccg
    42781 gtccgccgcc tcgcgtcggg cctgcagcaa ctcccacagc ctcgccatgt cctcgggcgt
    42841 gcggcgcagg gccgccgagt gggccgcctg cacatcgaag cagagctgca cctcgaacac
    42901 gtcgcggaca tcggcgagtt cgatgctctg gagcatcggc gcggggtcgg acaccgaccg
    42961 cacgaagatc cccttgccgc gctgcgactt cagcatcccc gtgtggacga gggcgctgac
    43021 cgcctctcgg atggtgggcc ggctcacccc cagcgcggcc gccagctcgg tctcgctggg
    43081 gatgcgtgat ccgacgggcc aggtgccggc ggccaactcg ccgtgcagga gggcgaggac
    43141 ctcgcgggtc gtcgacgaac ggcctatcgg acggaggggc atgggcgatt cctcggttgt
    43201 ctgacaactg acgtcaggct aatcaatgag ccgaggtgcc cacaagcaca tgaccagcca
    43261 agggatttga cgcctgcggc cgtgaccgtc gcgacgtgcc gaagccccgg aaggccgggg
    43321 cgacggatga ggtggcccgg gccttccggg gcagctgtgc gcgaggtgcc ctactgggcc
    43381 gggctggcgt ccagcacggc cgcgcggtcg acccgcgcaa ggccgccggg ctccacggcc
    43441 gtcgtcgccg tggcctccag ggtgcttgcg gactccacgg tgacgcttgt ggactcgagg
    43501 gtcacggtcg tggagaaggc ctcctggccg ttctgggtgc cggtcaccac gagccgcgaa
    43561 cggccgtacc cgtccggggc cttgggtgtg aggtcgagcc agcaaggcgc gtcgaactcg
    43621 acgtatcgga ggaacgtgct gtcgaaggcg gcgggacgcg cgtgccccgg cgccgaagcg
    43681 tgcacggcct gggccgcggc ttcgagtagc accatgcccg gcacgtggtc gtgcgggtgg
    43741 tcgaagagca cggggttcga ggtgtccgtg cgcagttggt agtggtgcgg cctggcggtg
    43801 ggcgcgatga cgacgtcccc gggggcggag cggtcgacca gggacggggg gacgggaggc
    43861 gccggcggca gtgcggtggc gaaggcttgc tgtgcgtcgg cgtactcccc gcgcaagcgg
    43921 ttgtagatgg cgggcgggtg ggtgacgtat ctgatctcgg aggagccgag gggctcaccg
    43981 gcgcaggtgg cgtcgatacg ggcggtcagg tggaccgagc cgagccggcg gcgggtgatg
    44041 tcgccgtgcg tgatgcgcag ttccacgtcg gtgggtgcgt ggcgctcccg gagcgccgcc
    44101 ggggcgaagg cgtagtgggc gtactcccag cccagacggt ggtcgagggg tatctcctgg
    44161 gatgtgtggg acaggacggc gagcgcctga cggacggttt cgacgaagaa cagcgggctg
    44221 gtgacgccgc tgcggagcgt gtagaaatca tgggagggcg gccagccgag agtgacgaca
    44281 tgggtctgcg gggagacctc gcgccaggta cggacgaaca cctcgtcggg tttcgactta
    44341 cgggcgaatc gctgcagatc ggcggtgggt aaaacggtgc gggcgctgct gtgcatgggc
    44401 gtcctccccc ttgggacgtc gaggtgcgga gctggtcaaa caccgtgaaa gggctcgatc
    44461 cgttgttcgg ttcgggagcc agcgttaaaa ataaagtcta ttcttttctt tgtcgagtgt
    44521 cggagttcgg gcggtgccat ggtaggtcga gtgatcaagc aggagcgtgc ggcgcggacc
    44581 agggtggcgc tgctgcacgc cgccgccgag gtgttcgccg agtccgggtt cgccggggcg
    44641 aacgtctcga acatcgcgga acgggcgggt ctcacgctgg gagccctgta cttccacttc
    44701 cggaacaaga gcgacatcgc ccgtgagatc gtgctcaacc agccggacct cgtcctgccg
    44761 ccgcatccct cccaagggtt gcagcacgcc gtggacatca ccctgacctg ggcgtaccag
    44821 ctgatcgacg acccggtgct gctcgccggg gcacggctgg tgatggagca ggagcacttc
    44881 gtcgaggccg aggagaactc ccaccagcag tggacgcgca tcctgggcca ggacctgcgc
    44941 gaagcacaac agcggcgcga actgcgggcg ggagtcgacg tggaggcgct ggcccggctg
    45001 gtggtcaacg cctgtaccgg cgcgcagatg cactcccatc tcgaaaccaa gcgccgcgac
    45061 ctgccgtacc gaatcgagga gatgtggcga tgtctgctcc cggccatcgc ggtgccgagc
    45121 gtgatcaaac gcctggagtt cggcgagtcg cgcgccagga aggcttgatg gccggcatgg
    45181 gggaacgacc gctgatcgtg gtgagcggcg ccacaggcgc ggtggggcga cacgtcgccg
    45241 ctcttctgga agggcgtgcg caggtccggc tgctcgtgcg ggacgtcggc aaggcccgcg
    45301 cgctcgggct caccggggag atcgtggccg ccgactatgc cgaccgccca ctgctggaca
    45361 aggccatgac gggggccgac gccgtcttcg tcgtgactgc gaacccgctg cgcccggaac
    45421 acgacgagaa cctgttggcc gccgcgcgct tggggggtgt gcggcacgcc gtgaagatct
    45481 cctggctcgg cgtcgcggat cccggtgcgg acgacctcat cgcccgctgg aaccgtgaca
    45541 gcgagcggct gctgcacacc tcggggctcg actggacggt gctccgcatg cgcagcccca
    45601 tgtcgaacac gctggcctgg gcgccggcga tccgtcagga gggggtggtc cgcgctctcg
    45661 gcggcgacgc gcggaccgcc tgcgtggacc cgcgcgatgt ggcggccgtg gcagtgcggg
    45721 cgctgacccg gccggggcac gagggcagaa cgtacgcgtt gaccgggccg gagcccctct
    45781 cgccccggga gcagacgcgg gtgctgtccc gcgttcttca acgaccgctg cgctttgagg
    45841 aactgacact caatcaggcc ctggacggat ggcgcagaaa gctgccggag ccggtggcgc
    45901 atgccctggc ggaggctgcc gcgcgtcggg gggccgtggc cgccgcgcac ccggaggaca
    45961 ccgtggccgc cgtcaccggc cggacggcga ggacgttcgc cacctgggcc ggggaccata
    46021 cggcgtactt ccgctgaagg gctgtggaac accgcggtcc gccgcgccgc gcgctgccag
    46081 tcttcccact gggctcgctg gggagcctgt ctccggactg cccggcgacc tcctgctgaa
    46141 ctccccgcac gacgaaaggc gatgatgtgc tcactggaag aacgatcatg gtgaccggtg
    46201 cgtccagcgg catcggcgag gccgccgcgc ggctgctcgc ggccgagggc gccgcgatcg
    46261 tgctcatggc gcgacgcgcg gacaggctgc gcgaactcgc ccggaacatc gaggacaagg
    46321 gcggccgggc ggcggtgtcc gtgggcgacg tccggtccgc ggcggacgtc gagcgagcgg
    46381 tgtcgacggc ggtggatacg ttcggttcgc tggacggcgc gttcaacaac gccggctggg
    46441 gcaccatcgg cccaccgttg cacgagatgg acgacgcgga ctacgaccgg atgatggacg
    46501 tcaacgtgcg tggcgtgtgg aactgcctgc gcaagcagat accggtgatg ctggcccagg
    46561 gctccggcgg ctccatagtg aacacctcca gcaccgcggg cctgttcgcc accggggcgt
    46621 cggctcccta tgtggcggcc aagcacgccg tcgccggact gacgaaggcg gccgcggcgc
    46681 agtacggcgg ccagggcatc cgggtcaacg cgctgatggt gggcagcaca cgcaccgagt
    46741 tgatggacgc ggcgatccag agcaatccgc aggtggagga gcactccgtc gcacgtgcaa
    46801 tccagcggcg gctggccgac ccgcaggagg tcgcccaggc cgtggtgtgg ctgtgcagcg
    46861 atcgctcctc gttcgtcacc ggcgccacgg taccggtgga cggcggctgc agcgcgatct
    46921 gaccccgccg ggtcggaggg cggaggcaca gcgaccgctc ctcgttcgtc accggcgcca
    46981 cggtagcggt ggacggcggc tgcagcgcga tctgaccccg ccgggtcgga gggcggaggc
    47041 cgatgcgggg aggggccctg cggtgggcgg cggcctttcc ccgagccctc gagcctgcgt
    47101 acagccgagg agcggaccga acagcgccgc cgcgccagga ccacgtggcc cgtcgccgtc
    47161 gcaccggccg cagtgtcctg gcaccgccgc cccggaagca agaaagtggc gcctgccgcc
    47221 cgacgcccgg cacgctcccc cactgcctca agggcgtggg aggtgccccc actcgccgaa
    47281 ccgcccgaaa gcccgagtac accccgtacg agcgcgtccg ggcggcacgc ggagagcaca
    47341 caccgacact cccatcagcc gctgccgcgg cgggcgcgcg gccgcccctc gggcgacgac
    47401 gccacgttcg caacaggcct taggcggccg cctggtggtc cagtgcgtcg tggcggaggt
    47461 ggtcgtagac gtacgcggcg gtcgcgaggg tcatgtggtg gtgccagccg gggaaggagc
    47521 ggccctcgaa gtcgagcagg ccgtagtcgt tctccagggt ccggatggcg ccgtgggtga
    47581 gtgcggcgcg gtgggtgagc gggacgacgt cggcgatgcg gtggtcgacg agggaggtga
    47641 tccagtagcg gtgcgggcgc ggcctcatgg ggaggaactc ggcgaacagc cggtggacgc
    47701 gctggccgcc atggctcgtg ggacccccgc ccggcaagcg gaccagggag gagcgcacgg
    47761 cggcgcgcct accgtgccca gagtggtcgg agcccagcgg gtgggggtgc cgcaggcccg
    47821 cgagccgcag cagctgctgg gcctcgacga aaccctcggg gacgacaccg gcaggtctgg
    47881 cgcggtgggc cgcaacgcgc tggctgggcc gtacctcgat gaggaagtcc cggccccgtg
    47941 cggtgagttg cgccgccagc cggaccgggt ccacgccgac gcacaggtcg gccacgaggg
    48001 tcgtacggcg tgagatccac ggcgtggaca gccggtcggc gctgtcgagc gcacgggccc
    48061 aggccggctg ttcggccgcc cagccgggta tgcgggcgcg gctgcgccgc ggttcgtccg
    48121 ccagccagcc gtcgggcagg agcagctgcc agtcgacggg gatgctccgg ctgtcggagg
    48181 ccaggaacag gccgatggcc acctggcagt tgagggtgcg tccggactcc ggaacgacgc
    48241 ggcgatggac gccgaccgag tggtctccgc gcttctctat gaccgtcaaa cccatggccc
    48301 acacgggccc cggcagtcgc gcggcggctt cctgggcgag gagctcgcgg gcggtcgtcc
    48361 agtcccaggg gcttgcgctg atgaactgct gtaaggcctg gtgcgcggcc tccggcgcac
    48421 cggaggcgcg ggctatctgc cggatggtct tcttgccctg cgcggtcagc agaccgcgca
    48481 ggtaggcgct cgcccaccgg cgctggtcgc ttcggggcag gtacccgaag acgttggagg
    48541 cgaagctggt cagcaggtcg gcgcagggcg cggccagggt gggggcgggg gcgagcgcgg
    48601 gcatgaggac tccgtccgtg gggaaacaat aaaaaaagat acaatctttt ttactgtcgt
    48661 ggacgggtaa atcgccgcac gcttaggtaa gttgacgttg cgtcgccgcc ttgaattggc
    48721 gagcgcgtaa cctcgagcac gccgatcgga tggaggcgag ggagcgtgac gcatgtcagc
    48781 gccccggcaa gcctcggccg gcctccgggg acgcgacggc cgggcggcga ggagagcggc
    48841 tatcgcgagg gcgggtagtg gtgtgatggt ccaggaaaga gcgacacgga cccggcgcgc
    48901 catggtgcac gccgcggccg aggagttcga ccgacgcggc tatcacgggg cgtcgctgtc
    48961 cgccatcagc cagacggtcg ggatgtccat gggagccctg acgttccact tcccgaccaa
    49021 ggaccgcctg gtcgaggcga tccacgccct cgggctcacc atgacgcagc gggagatggc
    49081 gcgggtcgag gagatcccgg gctgcccgat gcgccgggtg cgggccacac tcgtcgcgat
    49141 ctcccgtctc ctggaacacg aggcggtcgt ccgcggggcg gctcgtctcg gcgtcgagcg
    49201 gccgtgcccc ggttacgact ggacggcgac ctgggtcccg aagatccgag agctgctggg
    49261 gcaggcgcac tcggccgggt gcctgcgtac cgagccggca cccgaggacg tcaccgcgct
    49321 ggccgtcggt ctggtcgcgg cgttggcctc cgggctgcag tgctgggcgg gcgcaccggc
    49381 cggcgccgac cagatc
//
