LOCUS       NZ_CP022161            22548 bp    DNA     linear   CON 15-DEC-2024
DEFINITION  Streptomyces capitiformicae strain 1H-SSA4 chromosome.
ACCESSION   NZ_CP022161
VERSION     NZ_CP022161.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces capitiformicae
  ORGANISM  Streptomyces capitiformicae
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10989391)
  AUTHORS   Liu,C.
  TITLE     Streptomyces capitiformicae sp. nov., a novel actinomycete producing
            naphthoquinone compounds isolated from the head of Camponotus
            japonicus Mayr
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10989391)
  AUTHORS   Liu,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-2017) Life of Science, Northeast Agricultural
            University, No. 59 Mucai Street, Harbin 150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. Feb-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002214185.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 14:26:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,013
            CDSs (total)                      :: 9,935
            Genes (coding)                    :: 9,274
            CDSs (with protein)               :: 9,274
            Genes (RNA)                       :: 78
            rRNAs                             :: 2 (5S)
            complete rRNAs                    :: 2 (5S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 661
            CDSs (without protein)            :: 661
            Pseudo Genes (ambiguous residues) :: 0 of 661
            Pseudo Genes (frameshifted)       :: 220 of 661
            Pseudo Genes (incomplete)         :: 571 of 661
            Pseudo Genes (internal stop)      :: 32 of 661
            Pseudo Genes (multiple problems)  :: 155 of 661
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:06:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3703258
            Orig. end                         :: 3725806
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022161.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22548
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="15"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22548
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22548
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12548](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12548
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            62..1369
                     /locus_tag="CES90_RS16465"
     CDS             62..1369
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009307503.1"
                     /locus_tag="CES90_RS16465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_189783343.1"
                     /transl_table=11
                     /translation="MLDGSTGRARIAVLALLASVLVPLVAAGLRSVLWALAGIAGLALA
                     AVGVWWTLAHTGALRALGAALSVIGPVAVLALYATFGMLGPALLSLALWVLAVTAARTA
                     LSPGHTTSEQSEQAVAEAPHHPWILMNPRSGGGKVDRFHLVEKARAAGCRVILLEGGQD
                     VVELARQAVTEGADLLAVAGGDGTQALVAEVAARHDVPFVVVPAGTRNHFALDLGLDRD
                     DPAAALEALTHGVELRIDLGYAADRVFVNNASFGTYASVVTDPAYRDAKARTTLRTLPG
                     LLTGEDAPRLRARADGTYVDGLQALLVSNNPYGRAVDAAHPGRRERLDSGLLGVVCVRV
                     GNTAQAARLVRGRRSGGLIRLSAGEVVVEADTDILPVGIDGEHVVLPSPVVCRSAPGAL
                     RVRVPRRRPHAPRVSGGAADWPRVARLALGRLPVSE"
     misc_feature    complement(1561..1577)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.62"
                     /tool="antismash"
     gene            1695..3368
                     /locus_tag="CES90_RS16470"
     CDS             1695..3368
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.5"
                     /locus_tag="CES90_RS16470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_189783344.1"
                     /sec_met_domain="Pkinase (E-value: 4.3e-39, bitscore:
                     133.6, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDELRPGDPQIVGEYRLLGRLGSGGMGRVYLGRSAQGRTVAVKLV
                     HGELAVDPEFRQRFRREVEAARRVVGEWTAAVVAADTEAAVPWVATAYVPALTLHEAVE
                     RHGFLPEESVWALAFGLARALETIHGCGLVHRDLKPSNVLLGLDGPRVIDFGIARAADG
                     EGLTRTGMVVGTPGFLSPEQVNGVPVTGASDVFCLGAVLTFAATGRSPFAGAGQGAAAG
                     MVAVVSEPPVLDGITGPLRDLVERCLAKDPAGRPTPAHIAESAKDAGYDRSRPWLPPEL
                     LDHLGRHAARLLQVETPPPTTVDRPAGQPEAYWATQTATPRPGHPVPGPPRPLASPPAG
                     TPHPMAFPQPGTPQPGPVHPAAGVPHHPHPSPPWHAAATTPGSPSGRPGGQGTPGRPNR
                     SARNAVIVVAALVLAGVVVTNLVNGSSSSEGSEGSEGSDSPTASTAADGSVPSSFRYEG
                     TWRGTVTQGESNTYPIKTDYKGGKIGETVATVEYPTLDCGGIWVLVSQTDQGTQVEERI
                     TDGTSNCADEVAITLTPSTDGTLEYSFDSIERGRATLRRD"
     gene            complement(3379..3954)
                     /locus_tag="CES90_RS16475"
     CDS             complement(3379..3954)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019328167.1"
                     /locus_tag="CES90_RS16475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_189783345.1"
                     /transl_table=11
                     /translation="MTATYTFDVFSSLDGYGAAGGDWTGYWGKQGPELLDHRLALYGPE
                     QRMVFGANTYRAFERMLASSTEESDVRDPWVTRMRSLPTTVVSTTLEGPLDWPNATVVS
                     GDAVDVVARLKEESEVPLRSHGSLSMNRALMAAGLVDRLQVTLFPVITGRTGLDPIFQG
                     AADFDLELIENRTLDGHIQELTYRPTLH"
     gene            4088..4615
                     /locus_tag="CES90_RS49575"
     CDS             4088..4615
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116978.1"
                     /locus_tag="CES90_RS49575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_229913849.1"
                     /transl_table=11
                     /translation="MMRSRTSSTAVVAVVAVVVAVVFAALTSCSADSSDGSLAEDRPSV
                     SGSGSPASDPTPTPTQTATPSSSPTGPCADGTCEIEVAVGDVVTVPETYGLGPIEVTAI
                     SGDGVEMVAPLTGSGYSVSRCSGGGGVSSEGGGGVSLRCDEGPAATINDAMSLKVVEIR
                     DTAAVLRIEPAG"
     gene            complement(4658..5368)
                     /locus_tag="CES90_RS16485"
     CDS             complement(4658..5368)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015659025.1"
                     /locus_tag="CES90_RS16485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_189783346.1"
                     /transl_table=11
                     /translation="MTGNGTAGTTGSTAGTKARLYDAFATSGKALASGKRLELLDLLAQ
                     GERTVDALAKAAGLNLTTASAHLQTLKQAGFVATRREGVRIHYRLAGDDVAQLFALLRK
                     VAEAHQAAVPAARDAYLGDDGATEVTHEELRARVAAGDVVVLDVRPAEEYRAGHIPGAL
                     CVPIGELADRIGELPEETEIVVYCRGEYCVLAYDAVRLLTARGRRAIRLNDGMLEWRLA
                     DLPVEAVRPTSSGS"
     gene            5401..6795
                     /locus_tag="CES90_RS16490"
     CDS             5401..6795
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163: rhodanese domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996400.1"
                     /locus_tag="CES90_RS16490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_229913850.1"
                     /transl_table=11
                     /translation="MTPALEDPMRFADDHLIPLVDAGLGNSAYLVDLGDGRALAVDACR
                     DLRALRAAAERRGLTVAYAADTHLHADFLSGAVQLAHDDGAQVLASAAGRRAFPHVPLA
                     DGDETDLGGLTLRALATPGHTDEHLSFLLLDGDHALGVFTGGSLIVNSAARTDLLGAER
                     AEELARAQYRSLRRLAALPDATAVWPTHGAGSFCSAAEGAERTSTVGAQKRTNPLLAAP
                     DEDTFVRRLLAGLGSYPDYFDRLAEANRRGPAVLSAAPLLPGLTPAQVKSLLAEGGYVV
                     DVRPAAEYAAGHIPGALSVPLRDQFATWLGWLLPDTAPLVFITGEGQDLSEIVWQAYKI
                     GYERLAGRLRGGMAAWPADGNRQATTAFVTAERAGQRPYVDVRQEAEFAAGHVPGAVHI
                     ELGGLADRAADAPDGPVVACGHGERAMTAASLLERAGRTDLAVLRGGPDDYAAATGRRL
                     VEGTGR"
     gene            6966..8444
                     /locus_tag="CES90_RS49580"
     CDS             6966..8444
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004936958.1"
                     /locus_tag="CES90_RS49580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_229913851.1"
                     /transl_table=11
                     /translation="MRPVRLGLRENRAQFTLLVVVNVCVGGLVGLERTTVPLIGTDVFG
                     LTSDLAVFSFIIAFGVTKALTNLAAGALTARFRRKRLLVAGWLVGVPVPFALAWAPSWG
                     WIIAANVLLGLNQGLTWSMTVNMKIDLVGPARRGLATGLNEAAGYTAVGATALLTGYLA
                     TAYGLRPAPELIGVVFVTAGLALSLVVRDTAAHVALELARHTEPSPAGEGPRALLMDLR
                     GVATPGTFPRSRLLPHSRLRSSGRGPHEREGPHHRTGHKPKYIQSIYGAFRPARREHAP
                     DAAPSPTEIHQKGPGPAATFARTSWRDRSLRGACQAGLVNNLNDGLTWGVFPLLFTDHG
                     LGLAAVGLIKGLYPILWGLGQIPTGHLADRVGRKPLVVHGMLVQAAGLVLAPALLDRPL
                     LAGVLSAVFLGIGTAMVYPALIASVSDHAHPAWRANALGTYRFWRDLGYAAGALTAGVL
                     ADTLGLNATVIAAAALTTASGLLAARWMTERPVR"
     gene            8611..9303
                     /locus_tag="CES90_RS16505"
     CDS             8611..9303
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CES90_RS16505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_189783347.1"
                     /transl_table=11
                     /translation="MLMSTTGRLTSAAVATVAGLAVLAPAAHAVEQGPAKPAAKLTVAG
                     YTKYLQTQKSPEAKLALKKFLKLNKGQKAVFVKDLQDRRIYRALLSQARGPIGKPVSIT
                     DPHNKEVRFVTKVSSTVAKDKYRTTTVRFTVTEEIFKIPVTSETLTFSYATAGDGPRKT
                     VGSAKVTNVNAAIAIKNNPRVSIKGKLAQTRWVATPQVKSFGKAVVKKQDIHGNKATFR
                     AFLGNIDD"
     misc_feature    9404..9418
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     misc_feature    9583..9598
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 24.75"
                     /tool="antismash"
     gene            9700..9834
                     /locus_tag="CES90_RS16510"
     CDS             9700..9834
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="CES90_RS16510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_189783348.1"
                     /transl_table=11
                     /translation="MEQAQTDQKPVYEPPAVAEVAEFSELTTGCGFDFFEMPAQHNIC"
     misc_feature    9941..9959
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.79"
                     /tool="antismash"
     misc_feature    complement(9945..9963)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.2"
                     /tool="antismash"
     gene            10001..11869
                     /locus_tag="CES90_RS16515"
     CDS             10001..11869
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.5"
                     /locus_tag="CES90_RS16515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="asparagine synthase"
                     /protein_id="WP_189783349.1"
                     /sec_met_domain="Asn_synthase (E-value: 2.2e-35, bitscore:
                     122.1, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVMPESTAAGSGWFAVLPDCEAARAAASVLGAEAARIVEHASGR
                     PWLVGHWADGEVVVATVGDARVAAVGLTPLTGARLAALVREGDALGSLDRIAANGPTGS
                     CHLLASEAGRLRSQGTASGLRRLFSARVAGVMVACDRSDVLAAALDAGIDERLVALRLM
                     DPLIPHPLDERPLWRGVAAVPAGTALLTDPDGHARTRRWWHAPESDLPLAEGAERLAGA
                     LADAVAVRTADGGLISSDLSGGLDSTSLCFLAARGPARLLALTLTGSDPANDDLSWARR
                     AAGRLPDAEHLVLPTADLPAHYTGVLRAGEGVDEPALGGRVHAAFAETARRLADRGSRL
                     HLSGEGADQILSARTPYLHTTLRTRPRTAVTHLRATVSTQRWRLLPTLRALADNRSYGR
                     WLADTTQNLSPVLALDGSPALGWQMLRPQLPPWASRDAAGTVRELLWQTALEAEPLAGD
                     RGRHEVLWSVRNGTRLARQLTRVTSRAGLATHYPFYDDRVLEAALSVQLHERTTPFAYK
                     PLLVRAMRDAMPAELLTRSTKGEYSAEMQSGLRAHRAQLAELLDQPLLGTLGLVDADAL
                     RRACLSMFPPRLSPVTLEATLAVETWLRAHTGPAASTTALGSEAAA"
     gene            11866..12129
                     /locus_tag="CES90_RS16520"
     CDS             11866..12129
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009308634.1"
                     /locus_tag="CES90_RS16520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_189783350.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.2e-23,
                     bitscore: 82.1, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 1.1e-09,
                     bitscore: 37.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.7e-16, bitscore: 58.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGTTKLRRHVSASDVADGMVLLDERKGRYFKLNPSAALILRALL
                     DGSSPDEVARVLVERYEVSEERAAADVDALTAELAGIGLVVA"
     aSDomain        11878..12123
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CES90_RS16520_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="3.30E-26"
                     /identifier="RREFam002.1"
                     /label="CES90_RS16520"
                     /locus_tag="CES90_RS16520"
                     /protein_end="86"
                     /protein_start="4"
                     /score="82.1"
                     /tool="antismash"
                     /translation="TKLRRHVSASDVADGMVLLDERKGRYFKLNPSAALILRALLDGSS
                     PDEVARVLVERYEVSEERAAADVDALTAELAGIGLVV"
     aSDomain        11881..12045
                     /aSDomain="Lasso_Fused_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing fused peptidase in a lasso
                     peptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CES90_RS16520_Lasso_Fused_RRE.1"
                     /evalue="3.20E-12"
                     /identifier="RREFam003.1"
                     /label="CES90_RS16520"
                     /locus_tag="CES90_RS16520"
                     /protein_end="60"
                     /protein_start="5"
                     /score="37.4"
                     /tool="antismash"
                     /translation="KLRRHVSASDVADGMVLLDERKGRYFKLNPSAALILRALLDGSSP
                     DEVARVLVER"
     gene            12126..12548
                     /locus_tag="CES90_RS16525"
     CDS             12126..12548
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016640867.1"
                     /locus_tag="CES90_RS16525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_189783351.1"
                     /sec_met_domain="PF13471 (E-value: 3.3e-23, bitscore: 81.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVPSVFRTRPRLPLRRRPLPLLAVGAAHLIGRLSPLRIRQILTA
                     CSRGARPATYAEAARARGEVVAVSVRCAGQGCLPRSIATVLLCRVRGSWPTWRTGMRTV
                     PMVAHAWVEAEGQPVEDLPLTPGIPPLITVAPRKHP"
     gene            12595..13521
                     /locus_tag="CES90_RS16530"
     CDS             12595..13521
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104906.1"
                     /locus_tag="CES90_RS16530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_229913852.1"
                     /transl_table=11
                     /translation="MPGADIAVRTEELSKLYGTREALVGLDLTVPAGQVFGFLGPNGAG
                     KTTTIGILCTLLRPTLGHAWVAGAHVAREAGRVRRRIGVVFQEQTLDQDLTAMESMRMQ
                     AELYGLPGPAARAASTALLDLMGLADRAGHVVRTLSGGTRRRLEIARALVHGPRVLFLD
                     EPTTGLDPQTRAAVREHLRLLCREHGITVFLTTHHLEEAEHCDRIAIIDDGELVAEGSP
                     GELKAVIGADLVTLRTDDDERVAEAVRRLFGVATVTGPGGVRLRAPDGAALVPRLCAEL
                     TVPIHSVTVAPPTLDDVFLHHTGRTIR"
     gene            13569..14507
                     /locus_tag="CES90_RS16535"
     CDS             13569..14507
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056404.1"
                     /locus_tag="CES90_RS16535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_189783353.1"
                     /transl_table=11
                     /translation="MSSATTSESTSESTIESTIESTIDTSATATGAVIDEAGFRDGPFA
                     RFAQDLRTVRILWRREMVRFLRNRARLVMGLAAPLLFLFVLGNGIGSAGGALGLYQAFL
                     FPGTLLMVVQGPAVAVGTVIMWDRQSGFLRQMLVAPVRRAAILAGICLGGATTGALYAL
                     PVLALAGPMGVPYHPRLLLLLGEITLLAFALTALGVSAAVCIRRPETFQIVSGLAMAPA
                     VLLSGALFPVGGLPSWLGMVVRANPLSYGVDALRRTMPDPEPGGAATPSWFHAGPEWWG
                     WAPPVLLELALVVVPSLLLLTLAGRRFSRID"
     gene            15121..15768
                     /locus_tag="CES90_RS16540"
     CDS             15121..15768
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130071.1"
                     /locus_tag="CES90_RS16540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_229913853.1"
                     /transl_table=11
                     /translation="MSMSGRAEVVVRPSPVLRIAVIGDCPLFRHGVSQLIGTAPDLHLV
                     AAAASIEAADGSLRGAEVVLMDLQQSAPRLAAAVAKLRRQGHAVIVVSSSPRVDAVQVI
                     REGASGYLSRQAEGEEVLTAIRAVGSGRSYVCAPAGQLLGPSPRFTDREQEILRLVADG
                     ATDHEIAARLRISKHTVQSHLDRIGEKTGSRRRSDLTRLAVESGLTDAEQPE"
     misc_feature    complement(15873..15888)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.59"
                     /tool="antismash"
     misc_feature    complement(15991..16005)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.39"
                     /tool="antismash"
     misc_feature    15992..16003
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.36"
                     /tool="antismash"
     gene            16056..16430
                     /locus_tag="CES90_RS16545"
     CDS             16056..16430
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CES90_RS16545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_189783354.1"
                     /transl_table=11
                     /translation="MRKRVILALAAVLPLTGVATLAGASQAAADPTKSRVVVQGTVEDC
                     EDDTAPLQVTIETKKDEVGVDSKPRVEDEGKYKVTFKNIPKNGVKATATVECEEDSYST
                     SLTIKRPPGTKLTQTFNIEP"
     misc_feature    complement(16562..16580)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.02"
                     /tool="antismash"
     gene            16700..17698
                     /locus_tag="CES90_RS16550"
     CDS             16700..17698
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CES90_RS16550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_229913854.1"
                     /transl_table=11
                     /translation="MSYPPPPQGGAWPSGQGQYPGQPQYPGMAPQSQYPGVAPQPPYPG
                     TAPQPQYPGTAPQPQYPGAAPHPHQYPVPPPRPGGVPLPPPKSSGTGLGCLAAVLGVFG
                     VLGMLGGGFLVSHAYSNHSQVISNGGEYGPTMWRNEPADAFFPEVLAPVNSATENDPKR
                     ATWHRLGISEDTGCEDGLNKVTAAAVRDLDCEAVLRATYVDPTGNTVGTVSVIVLPEGG
                     SAQMTEFFEKDADKLDPEVGAKPYAVPGTVAAKWSGARSNGGAGMELGGMPYVLVASTG
                     AVDGRKAGELPGEWGSHSWSAGDDRAPWRGAAKALCDDMEVHLMNLLRETS"
     gene            17695..18867
                     /locus_tag="CES90_RS16555"
     CDS             17695..18867
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019354044.1"
                     /locus_tag="CES90_RS16555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S8 family serine peptidase"
                     /protein_id="WP_189783355.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 7.5e-38, bitscore:
                     129.6, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVRRTAVAVAASLIGLTASASASGTATAAPRAAETVPQSWEYSA
                     LNLAQAHRAAQGEGVTVAVLDSGVEAGHPALAGKVTTGPDYVEDGLQPGDPKWGDHGTA
                     MASDVLKVAPKAEILSIRITSDKDEDGFYRGTSRIARGIDYAIEHGADVISMSIGGELL
                     GDSYDEDEADALGRAAQAGVPVLASAGNSGDEFNDAQYPAGYPGVIAVAALQQSGTRAE
                     FSTVRTYNSVAAPGVAIMSAKNTGGYEAINGTSPATALSAGVVALMKSANGDLTSAQVR
                     SILTRTARHASSGPSPLDGYGMIDAAAAVESSAKPPADRTEPIAHKGKEHLATPDGTPK
                     TQHPPLDTELVAIGGAAAAVGLVMVIGALLSARAARRRGTRARAQQAGQG"
     gene            complement(19015..20022)
                     /locus_tag="CES90_RS16560"
     CDS             complement(19015..20022)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005476488.1"
                     /locus_tag="CES90_RS16560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphotransferase enzyme family protein"
                     /protein_id="WP_189783356.1"
                     /sec_met_domain="APH (E-value: 1.7e-21, bitscore: 76.4,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSRAGFIATMYGLGGECGVGPGSPAWDMTPVARGALGQIWKLSS
                     GNGFSWAVKELLFGCDEGQVQREAALRNAAEGLGISAPRFLPDRTGAYVSRLPSSMGGS
                     YVKLYDWVDGVEADPADPEILAWCGRTLALLHRAGEGASGEPNAWYEECPRPADWAELY
                     EAVRRAGVPWADELGRFITTSAGELADHVTPSGAGDVVVSHLDMRPQNVLVGPAGPALL
                     DWDNAGLISAERELARAVHVWAGGNDFDADSARRLVRAYVDAGGPAVVKGLDSFSMLFA
                     TDLNYVRVQAGCAIDPNVTPAQREFASDQVLTALRSLPDPAAAARLTEALASEW"
     gene            complement(20027..21490)
                     /locus_tag="CES90_RS16565"
     CDS             complement(20027..21490)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014146499.1"
                     /locus_tag="CES90_RS16565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_189783357.1"
                     /transl_table=11
                     /translation="MSIADTDTDTDTDTDTGALTPRLKLTLVLLLAAQFMLAVDFSILN
                     VALPVIGDGLGFSSAGLQWIATSFALCAAGCTLLFGRVADLFGRRRLFLGGLVVLGAAS
                     LVGGLAQDPEVLIVARVFQGLATAAVTPAGLSLLTTSFPEGPLREKALGLNGALMSAGF
                     TAGAILGGLLTELLSWRWAFFVNVPVVLAVLLIAPTVIRESRPDERPRLDVPGAVSVTL
                     GLLAVVLGLTRAGEHGWGSASALLWLAAGAVLLLVFYGVERRVSEPLVPVGVLGKRSVA
                     WGNVAGLIAFLTETSLVFLLTLYLQEVLGFSPLAAGLSFGVLGVGTVVGGTLAPRVIGR
                     VGSRRTLIVGGVVQTVFTVALLGMGDDRSSMWLLLAGTFAGGVGNMLVIVGFMVTATSG
                     LDDHEQGLATGLATMTQQIGITMGTPIMSAVATAAATGGGAAVMLGGLKAAIALNAALV
                     LLGTLTSALFLRGAAPRQAGEPVGSTAER"
ORIGIN
        1 cgtcagagtg gaatcacacg gcggggacac caggggatcg ggagggacag gacccccgac
       61 ggtgcttgac ggcagtaccg ggcgcgcccg catcgccgta ctcgccctgc tggcaagcgt
      121 cctggtgcca ctcgtcgccg ctggtctgcg gagtgtgctg tgggcgctgg ccggcatcgc
      181 cggactcgcg ctggccgccg tcggcgtgtg gtggaccctg gcgcacaccg gtgcgctccg
      241 agccctcggg gcggccctgt cggtgatcgg gccggtcgct gtcctcgctc tgtatgccac
      301 gttcggcatg ctcgggccgg ccttgctgtc cctggctctg tgggtcctgg ccgtcacggc
      361 ggcacgtacg gccctgagcc ccgggcacac cacctccgag cagtccgaac aggctgtcgc
      421 cgaggcgccg caccacccct ggatcctcat gaatccgcgc tccggtggcg gcaaggtcga
      481 ccgtttccat ctggtggaga aggcccgggc ggccggctgc cgggtgatcc tgctcgaagg
      541 cggccaggat gtcgtcgaac tggcccggca ggcagtcacc gagggggccg atctgctggc
      601 ggtggcgggc ggcgacggca cccaggcact ggtggccgag gtcgcggccc gccacgacgt
      661 gccgttcgtg gtggttcccg ccggcacccg caaccacttc gccctcgatc tcggcctcga
      721 ccgcgacgat cctgcggcgg ccctggaagc actgacccac ggcgtcgaac tccgcatcga
      781 cctcgggtac gccgcggacc gggtcttcgt caacaacgcc tcgttcggaa catacgcgtc
      841 cgtcgtcacc gaccccgcgt accgggacgc caaggcccgc acgaccctgc gcaccctccc
      901 cggccttctc accggcgagg acgcacccag actgcgggcg cgggccgacg gaacgtacgt
      961 cgacggactc caggcactcc tcgtcagcaa caatccctac ggacgggccg tcgacgcggc
     1021 ccatccgggg cgcagggagc ggctggactc gggccttctc ggcgtggtgt gtgtgcgggt
     1081 cggcaacacc gcccaggcgg cacgcctggt gcgcggtcga cgctccgggg gactcatccg
     1141 gctgagcgcc ggggaagtcg tcgtcgaagc cgacaccgac atcctcccgg tcggcatcga
     1201 cggagagcac gtcgttctgc cgtcgcccgt cgtgtgccgc agcgcgcccg gggcgctccg
     1261 ggtgcgtgtg ccgcgccgtc gtccccacgc accgcgtgtc agcggcgggg cggccgactg
     1321 gccgcgcgtg gcacggttgg cgctggggcg cctgcctgtt tccgagtgag tggctcagcc
     1381 agccccatgc cggcagctcg tccccatcag ccgtactgct tgatgtggcc gtgagctgcg
     1441 gcttcttacg gatcaggcag ggctttcggg ccccgccctc gtcatgtgcc gggtggggcc
     1501 gtcgggcggc caggtgccta cgaaatcgtc acagaagaaa acgccgtcaa cggatcgtaa
     1561 gtatcccatc ggggtcggag agttgacaca atcgcggtca ggtactggtc ggagcggcgt
     1621 gccccacttg ccgggtgagg acgggccgtt gcccgcacca aaacaagagg gcggctccag
     1681 tgacgggggt tggcatggac gagctcaggc ccggcgatcc gcagatcgtg ggggagtatc
     1741 ggctgctcgg ccgtctgggg tccggcggca tgggccgggt ctacctgggg cgttcagcgc
     1801 agggccgcac cgtggcggtc aagctggtgc atggcgaact cgcggtggac ccggagttcc
     1861 gtcagaggtt ccggcgagag gtcgaggccg cccgaagagt ggtgggcgaa tggaccgcag
     1921 cggtggtggc ggcggacacg gaagctgccg tgccctgggt ggcgacggcc tatgttcccg
     1981 cactgacgct gcacgaggca gtggagcggc acgggttcct gccggaggag tcggtgtggg
     2041 cgctcgcctt cggactggcg cgagcgctgg agaccattca cggctgcggg ctggtgcacc
     2101 gggacctgaa accgtccaac gtgctgctcg gcctggacgg gccacgggtg atcgacttcg
     2161 ggatcgcgcg cgcggccgac ggtgaggggc tcacccgtac gggcatggtg gtgggcaccc
     2221 ccggattcct ctcccccgag caggtgaacg gcgtgcccgt caccggggcg agtgacgtct
     2281 tctgcctggg ggccgtgctc acgttcgccg cgaccggacg atccccgttc gccggcgccg
     2341 gccagggagc cgcggcgggc atggtggccg tcgtcagtga gccgcccgtc ctcgatggca
     2401 tcaccggccc gctccgcgac ctggtggaga gatgcctcgc caaggacccg gcggggcgcc
     2461 ccacgcccgc gcatatcgcc gagtcggcca aggacgccgg gtacgaccgc tcccgtccct
     2521 ggcttccgcc ggaactgctg gaccacctcg ggcggcacgc cgcacggctg ctgcaggtgg
     2581 agacgccgcc tcccaccacg gtggacaggc ccgccgggca gccggaggcg tactgggcca
     2641 cccagacggc cactccccgt ccgggtcacc cggtacccgg cccaccgagg cccctcgcgt
     2701 cccctcccgc aggcacgccg catcccatgg cctttcccca gcccggaaca ccacagcccg
     2761 gccccgtcca tccggcggcc ggcgtaccgc accacccgca cccctcccct ccgtggcatg
     2821 ccgcggccac cacgcccggc agcccttcgg gcaggccggg cgggcagggc acgccgggca
     2881 ggccgaacag gtcggcccgg aatgcggtca tcgtggtggc ggctctggtc ctcgcgggcg
     2941 tggtggtcac gaatctggtg aacggatcct cctcatcgga aggctcggaa ggctcggaag
     3001 gctcggattc accgacggcc tcgaccgccg ctgacgggtc cgtgccgtcc tcgttccgct
     3061 acgagggcac ctggcggggc acggtgacgc agggcgagag caacacctat cccatcaaaa
     3121 cggactacaa gggcggcaag atcggcgaaa ccgtggccac ggtcgagtac ccgacgctgg
     3181 attgcggcgg tatctgggtg ctcgtttcgc agaccgacca gggcacccag gtggaggagc
     3241 ggatcacaga cggcacatcg aactgtgccg acgaagtggc catcaccctc acaccgtcga
     3301 cggacggcac actcgagtac tcgttcgact ccatcgagcg cggccgggca acactgcgac
     3361 gggactagac cgacccggtc agtgcagggt gggccggtag gtgagctcct ggatgtggcc
     3421 gtcgagcgtt cggttctcga tcagctcaag gtcgaagtcg gctgcgccct ggaagatcgg
     3481 gtccaggccg gtccgaccgg tgatgacggg gaagagcgtc acctgcaagc ggtcgaccag
     3541 gccggcggcc atcagcgccc ggttcatcga caggctgccg tgcgagcgca acggcacctc
     3601 ggactcctcc ttgagccggg cgacgacgtc gacggcgtca ccgctcacga cggtcgcgtt
     3661 cggccagtcg agagggcctt ccagcgttgt cgacaccacc gttgtcggca ggctcctcat
     3721 ccgggtgacc cacgggtcac gtacgtcgga ctcctcggtg ctcgaggcca gcatccgctc
     3781 gaacgcccga taggtgttgg ccccgaagac catccgctgc tccgggccgt acaaggcgag
     3841 gcggtggtcg agcaactcgg ggccctgctt gccccagtag ccggtccagt cgccgccggc
     3901 ggcgccgtag ccgtcgaggc tggagaagac gtcgaaggtg taggtagcgg tcatgtcgtt
     3961 ctccttgagt gcggtgggtt cggcgaccct cgcacccata gacccggcac gcttccgaaa
     4021 ctcatcgctg tgcccaccgg gcggcggcgg ggaggggtcc cgggcggggc cgggttccat
     4081 ggtgcccatg atgcgcagca gaacgtcatc caccgctgtc gtcgctgttg tcgccgttgt
     4141 cgtcgctgtc gtgttcgccg ctctcacgtc gtgttccgcg gattcttcgg acgggtccct
     4201 cgccgaggac cggcccagtg tgtccggctc cgggtcaccg gcgtccgacc ccacgccgac
     4261 tcccacgcag acagccacgc cgtcgtcctc gccgaccggg ccgtgcgccg acgggacgtg
     4321 cgagatcgag gtggccgtgg gggacgtcgt gaccgtgccg gaaacgtacg gcctcgggcc
     4381 gatcgaggtg acggcgatca gcggcgacgg ggtcgagatg gtcgcgccgc tgacggggtc
     4441 gggctacagc gtttcgcgct gttccggtgg cggcggcgtg tcgtcggagg gtggcggcgg
     4501 tgtcagtctg cgatgcgacg agggacccgc cgcgaccatc aacgacgcca tgagcctgaa
     4561 ggtcgtcgag atccgcgaca ccgccgccgt cctccgtatc gaacccgccg ggtgacgtac
     4621 ggctcggccc ttggggcagg gctgcgtagc tgtcggctca ggagccggag gacgtcggcc
     4681 ggaccgcctc gacgggcagg tcggccaggc gccactccag catgccgtcg ttgagacgga
     4741 tcgcgcggcg gccgcgggcc gtcagtaggc gtacggcgtc gtaggcgagc acacagtact
     4801 cgccccggca gtacacgacg atctccgtct cctccggcaa ctcaccgatg cggtcggcca
     4861 gttcaccgat ggggacgcag agcgcgcccg ggatgtgccc ggcccggtac tcctccgccg
     4921 ggcgtacgtc cagtacgacc acgtcgcccg ccgcgacgcg ggcgcgcagt tcctcgtggg
     4981 tgacctcggt cgcgccgtcg tcgccgaggt aggcgtcgcg ggcggccggt acggcggcct
     5041 ggtgcgcctc ggcgaccttg cggaggagcg cgaacagctg ggccacgtcg tcgccggcca
     5101 gccggtagtg gatgcgtacg ccctcgcggc gggtggcgac gaaaccggcc tgtttcaggg
     5161 tctggagatg cgccgacgcc gtcgtcaggt tcagcccggc cgccttggcc agggcgtcga
     5221 ccgtgcgctc gccctgggcc agcaggtcga gcagttccag ccgctttccg ctggccagcg
     5281 ccttgccgct ggtcgcgaac gcgtcgtaca gccgcgcctt cgtacccgct gttgaacctg
     5341 tcgtaccggc tgtgccgttt cccgtcatgc catcctccat agatccatgg aatagtgtag
     5401 atgaccccgg ccttggagga ccccatgcgt ttcgccgacg accatctgat ccccctggtc
     5461 gacgccgggc tgggcaacag cgcctacctc gtcgacctcg gtgacggccg cgccctggcc
     5521 gtggacgcgt gccgtgacct gcgtgccctg cgcgcggccg ccgagcggcg cgggctgacc
     5581 gtggcgtacg cggcggacac ccatctgcac gcggacttcc tctccggcgc ggtccagctc
     5641 gcccatgacg acggtgcgca ggtgctggcc tccgccgccg gacggcgggc cttcccccac
     5701 gtaccgctgg cggacggcga cgagacggac ctcggcggcc tgaccctgcg ggccctggcc
     5761 acccccggcc atacggacga gcacctgtcc ttcctgctcc tggacggcga ccacgcactc
     5821 ggcgtcttca ccggcggctc gctcatcgtg aactcggccg cccgcaccga cctcctcggc
     5881 gccgaacgcg ccgaggaact cgcccgcgcc cagtaccgct cgctgcggcg gctggcagcg
     5941 ctgccggacg cgaccgcggt gtggcccacc cacggtgccg gttccttctg ctcggctgcg
     6001 gagggcgcgg agcgtacctc caccgtcggc gcgcagaaac ggaccaaccc cctgctggcc
     6061 gccccggacg aggacacctt cgtacggcgc ctgctggccg gcctcggcag ttacccggac
     6121 tacttcgacc ggctcgccga ggccaaccgg cgcggccccg ccgtcctgtc cgccgcaccg
     6181 ctgctgcccg gcctgacccc cgcgcaggtc aagtccctcc tcgccgaggg cggttacgtc
     6241 gtcgacgtcc gaccggccgc cgagtacgcg gccggacaca tcccgggcgc gctctccgtc
     6301 ccgttgcgcg accagttcgc cacctggctg ggctggctgc tgcccgacac cgcgcccctc
     6361 gtcttcatca cgggcgaggg ccaggacctc agcgagatcg tctggcaggc gtacaagatc
     6421 gggtacgagc gcctcgccgg gcgtctccgt ggtggcatgg ccgcctggcc ggccgacggc
     6481 aaccggcagg ccacgaccgc gttcgtcacc gccgagcgtg ccgggcaacg gccgtacgtc
     6541 gacgtacggc aggaggcgga gttcgccgca gggcacgttc cgggcgcggt gcacatcgag
     6601 ctcggtgggc tcgccgaccg tgccgccgac gccccggacg ggcccgtcgt ggcgtgcggc
     6661 cacggtgagc gggccatgac cgccgccagc cttctcgaac gcgcgggccg caccgacctc
     6721 gccgtcctcc gcggtggacc ggacgactac gcggcggcca ccgggcgacg actcgtcgag
     6781 ggcaccggca ggtgagggat ggtcctgggg atggtcccgg gcgtcggcag gtgagggctg
     6841 gtgcagggga cgggcaggtg agggctggtg caggcgacgg gcaggtgagg gctggtgcag
     6901 gcgacgggca ggtgagggct ggtgcaggcg acgggcaggt gaaggccggc gcaggacacc
     6961 gccgggtgag gcctgttcgt ctgggcctgc gggagaaccg ggcgcagttc accctgctcg
     7021 tcgtcgtcaa cgtctgcgtc ggtggcctgg tcggcctgga acgcaccacc gtcccgctca
     7081 tcggcaccga cgtcttcggt ctgaccagcg acctggccgt cttctccttc atcatcgcct
     7141 tcggggtcac caaggcgctg accaacctcg ccgccggcgc cctgaccgcc cgcttccgcc
     7201 gcaagcggct cctcgtcgcc gggtggctgg tcggcgtccc cgtccccttc gccctcgcgt
     7261 gggcgccgtc gtggggctgg atcatcgccg cgaacgtcct gctcggcctc aaccagggcc
     7321 tgacctggtc gatgacggtc aacatgaaga tcgacctggt cggcccggcc cgccggggcc
     7381 tggccaccgg cctcaacgaa gccgccggtt acacggcggt cggcgccacc gccctcctca
     7441 ccggctacct cgccaccgcg tacggtctgc gtcccgcccc cgagctcatc ggcgtcgtct
     7501 tcgtcaccgc cggactcgcc ctctccctcg tcgtccgcga caccgccgcc catgtcgccc
     7561 tcgaactcgc ccggcacacc gagccgtcgc ccgccggcga gggccccagg gcccttctga
     7621 tggatctgcg tggcgtcgcg acgcccggca cgttcccccg ctcccggctt ctcccccact
     7681 cccggcttcg ctcgagcggg aggggccccc atgagcggga gggcccccac caccgcaccg
     7741 ggcacaagcc caagtacatc cagtccatct acggggcctt ccgcccggca cgccgagagc
     7801 acgcaccgga cgccgctcct tcgcccacgg agatccatca gaagggccct ggcccggccg
     7861 ccaccttcgc ccgtacgtcg tggcgcgacc gttccctgcg cggcgcctgc caggccggcc
     7921 tggtcaacaa cctcaacgac ggcctgacct ggggcgtctt cccgctcctc ttcaccgacc
     7981 acggcctcgg tctcgccgcc gtcggcctga tcaagggcct ctacccgatt ctgtggggcc
     8041 tcggccagat ccccaccggg cacctcgcgg accgcgtcgg ccgcaaaccc ctcgtcgtcc
     8101 acggcatgct cgtccaggcc gccggtctcg tcctcgcccc ggccctgctc gaccgcccac
     8161 tgctcgcggg ggtcctctcc gccgtgttcc tcggcatcgg cacggccatg gtctacccgg
     8221 ccctgatcgc ctccgtctcc gaccacgccc accccgcctg gcgcgcgaac gcactcggca
     8281 cgtaccgctt ctggcgcgac ctcggctacg ccgccggcgc cctgaccgcc ggcgtcctcg
     8341 ccgacaccct cggcctgaac gccaccgtca tcgccgccgc cgcactgacc accgcgtcgg
     8401 gcctcctcgc ggcgcggtgg atgacggaac ggccggtgcg gtgagcagga cgctgttgga
     8461 ggttcagccc gcccgcacca gaccgccgtc ggccgatcgg gcagtgtcct tccgggcagt
     8521 ggctggagag acaatttcgg ccaaggccgg gcgttcgtaa ggtcgttggc gcaggcaatc
     8581 gcacacgcac gcgtcaacgg ggagttccac atgctcatgt ccaccaccgg ccgtctcacg
     8641 tcggccgcgg tcgccaccgt cgccggtctc gcggtgctcg cgcccgcggc tcacgccgtg
     8701 gagcagggcc cggccaagcc ggccgcgaag ctgaccgtcg ccgggtacac caagtacctc
     8761 cagacgcaga agtctcccga ggcgaagctg gcgctcaaga agttcctgaa gctgaacaag
     8821 gggcagaagg ccgtcttcgt caaggacctt caggaccgca ggatctaccg ggcgctgctc
     8881 agccaggcga ggggtcccat cggcaagccg gtcagcatca ccgacccgca caacaaggaa
     8941 gtccggttcg tcacgaaggt cagctccacc gtcgccaagg acaagtaccg caccaccacc
     9001 gtccgcttca ccgtgaccga ggagatcttc aagatcccgg tcaccagcga gaccctcacc
     9061 ttcagctacg cgaccgccgg cgacggcccg cggaagaccg tcggctccgc caaggtcacc
     9121 aacgtcaacg cggccatcgc catcaagaac aacccgcgcg tcagcatcaa gggcaagctc
     9181 gcccagacca ggtgggtcgc caccccgcag gtgaagtcct tcggcaaggc cgttgtcaag
     9241 aagcaggaca ttcacggcaa caaggccacc ttccgggcct tcctcggcaa catcgacgac
     9301 tgacacccgg cccacccggc tcaacccccc tcgccctcac cacaggaaac ggctcgcccg
     9361 gcacagtccg cggcgggccg ttttcgtatg cggaccgcct gcttgacggt ttcggccatt
     9421 gtcggattac cggggaaagg gcccgggaaa gcgacggcga atcaccagga gggagggttt
     9481 gagcggacct cgctggacgc cgacggatcc gcagccccat catcgcccgc gcgaacgccg
     9541 accgacccga cccgcccata cggataaaac ggcaccgcaa actcgaattc ctgctcgata
     9601 ttcgcctttc cgtcgcggcg aaaaccgccc cttgtgagcc gtacgtccgg catcgcagca
     9661 tgtatccgga atttccgtct acccggaagg aaacacgcga tggagcaggc ccagacggac
     9721 cagaagccgg tgtacgagcc gccggcggtg gccgaggtcg ccgagttctc ggagctgacc
     9781 accggttgtg ggttcgactt cttcgagatg cccgcccagc acaacatctg ctgagccgga
     9841 tcgtcacctc gcgtcgagcg tgagtcgcac gtgacgggtc gcggccgggt cggcgcccgc
     9901 ccttttcggg acgagcgcgt gaaatcccgg ccgcgactgg aattcgttca ccgaatacac
     9961 cttttcgagg ccgggaaggc cgggaaaaca ccagggggtc atgagcgtga tgccggaaag
    10021 cacggcggcg ggcagcggct ggttcgcggt tctcccggac tgcgaggcgg cgcgggcggc
    10081 cgcctcggtc ctgggcgcgg aggcggcgcg gatcgtggag cacgcctcgg ggcggccgtg
    10141 gctcgtcgga cactgggccg acggcgaggt cgtcgtcgcg acggtcggcg acgcccgggt
    10201 ggcggccgtg ggcctcaccc cgctgaccgg agcccgcctc gccgcactcg tccgggaagg
    10261 cgacgcgctc ggctcgctcg accggatcgc cgcgaacggc ccgaccggca gctgccatct
    10321 gctcgcgtcc gaggcgggcc ggctgcggtc ccaggggacg gcctcggggc tgcggcggct
    10381 gttctccgcc cgggtggccg gtgtcatggt cgcctgtgac cgctcggacg tcctggccgc
    10441 cgccctcgac gcgggcatcg acgaacgcct ggtggccctc cgcctcatgg acccgctgat
    10501 cccgcacccc ctcgacgaac gccccctgtg gcggggcgtg gcggcggtcc cggccggtac
    10561 ggcactgctg accgaccccg acggccacgc ccgtacgcgg cgctggtggc acgcacccga
    10621 gtccgacctc cccctcgccg agggcgcgga gcggctggcc ggggcgctcg cggacgcggt
    10681 cgccgtacgc accgccgacg gcgggctgat cagctcggac ctgtccggcg ggctggactc
    10741 cacctcgctg tgcttcctgg ccgcgcgggg gcccgcccgg ctgctcgccc tcaccctcac
    10801 cggctccgac cccgccaacg acgacctctc ctgggcccgg cgggccgcgg gccggctgcc
    10861 ggacgccgag catctggtgc tgccgacggc cgacctgccg gcgcactaca ccggggtgct
    10921 gcgcgcgggc gagggtgtcg acgaaccggc cctcgggggc cgcgtccacg ccgcgttcgc
    10981 cgagaccgcg cgccgcctgg cggaccgggg ctctcggctg catctgtccg gggagggcgc
    11041 ggaccagatc ctgtccgcgc gcacgccgta cctgcacacc acgctccgca cccggccccg
    11101 caccgccgtc acccacctgc gcgccacggt ctccacccag cgctggcgcc tgctgccgac
    11161 gttgcgggcg ctggccgaca accgctcgta cgggcgctgg ctcgccgaca ccacccagaa
    11221 cctctccccc gtactggccc tggacggttc ccccgccctg ggctggcaga tgctgcggcc
    11281 ccaactgccg ccctgggcaa gccgggacgc ggcgggcacc gtacgggaac tgctctggca
    11341 gaccgccctc gaagccgagc ccctcgccgg cgaccgcggc cggcacgagg tcctgtggtc
    11401 cgtgcggaac ggcacccggc tggcccgtca gctcacccgc gtcaccagcc gggcgggtct
    11461 ggccacgcac taccccttct acgacgaccg cgtactggag gcggccctgt ccgtacagct
    11521 gcacgagcgc accaccccct tcgcgtacaa gccgctgctg gtgagggcga tgcgggacgc
    11581 gatgcccgcc gagctgctca cccgcagcac caagggcgag tacagcgccg agatgcagag
    11641 cggtctgcgc gcccaccgcg cccagctggc ggagctgctc gaccagccgc tcctcggcac
    11701 gctcggcctc gtcgacgccg acgccctgcg ccgggcctgt ctgagcatgt tcccgccccg
    11761 gctgtcgccg gtcacgctgg aggcgaccct ggccgtcgag acctggctgc gcgcccacac
    11821 cggaccggcc gcgtccacca ccgccctggg aagcgaggcg gcggcatgaa cgggaccacc
    11881 aagttgcggc ggcacgtctc cgcctccgac gtcgcggacg gcatggtcct cctcgacgag
    11941 cgcaagggcc gctacttcaa gctgaatccg agcgccgccc tgatcctgcg cgccctgctc
    12001 gacggctcct cgccggacga ggtggcgagg gtcctggtcg agcggtacga ggtctccgag
    12061 gagcgggcgg ccgccgatgt cgacgcgctc accgccgagt tggccggcat cgggctggtg
    12121 gtcgcgtgag cgtccccagc gtcttccgga cccggccccg gctgcctctg cgccgacgcc
    12181 cgctgccgct cctcgcggtg ggcgccgcgc acctgatcgg ccggctctcc ccactgcgca
    12241 tccggcagat cctgaccgcc tgttcgcgcg gcgcccgccc cgcgacgtac gccgaggccg
    12301 cgcgggcgcg cggtgaggtg gtcgcggtga gtgtgcgctg cgccgggcag ggctgtctgc
    12361 cgcgctccat cgccaccgtg ctgctgtgcc gcgtccgcgg cagctggccg acctggcgta
    12421 cgggcatgcg tacggtcccg atggtcgccc acgcgtgggt ggaggcggag ggccaaccgg
    12481 tggaggacct gccgctcacc ccgggtatcc cgccgctcat caccgtcgcg ccacggaagc
    12541 acccataagg actcataagg acttatgcag actcataaca gagggggagc catcgtgccg
    12601 ggcgccgaca tcgccgtacg caccgaggaa ctcagcaagc tctacgggac ccgcgaggcc
    12661 ctggtcggac tcgacctcac cgtcccggcc ggccaggtct tcggcttcct cggccccaac
    12721 ggggcgggca agaccaccac catcggcatc ctgtgcaccc tgttgcggcc gacgctgggc
    12781 cacgcgtggg tggccggggc gcatgtggcc cgcgaggccg ggcgggtacg gcgccggatc
    12841 ggcgtcgtct tccaggaaca gaccctcgac caggacctga cggccatgga gagcatgcgc
    12901 atgcaggccg agttgtacgg gctgcccggc ccggcggccc gcgccgccag taccgcgctg
    12961 ctcgacctga tgggcctcgc cgaccgggcc ggccacgtcg tacgcaccct ctccggtggc
    13021 acccgccgcc gactggagat agcccgggcg ctggtgcacg gtccccgggt gctcttcctc
    13081 gacgagccca ccaccgggct cgacccgcag acccgggccg ccgtccggga gcatctgcgg
    13141 ctgctgtgcc gggagcacgg catcaccgtg ttcctgacca cgcatcatct ggaggaggcc
    13201 gagcactgcg accgcatcgc catcatcgac gacggcgaac tggtcgcgga gggctcgccc
    13261 ggggagctga aggcggtcat cggcgccgac ctcgtcaccc tgcgcaccga cgacgacgag
    13321 cgggtcgccg aggccgtacg ccggctgttc ggcgtcgcga cggtgaccgg gcccggcggc
    13381 gtacggctgc gcgcgcccga cggggccgcc ctggtccccc ggctgtgcgc cgaactcacc
    13441 gtccccatcc actccgtgac cgtcgccccg cccaccctcg acgacgtgtt cctgcaccac
    13501 acgggccgca cgatccgcta gacgcgtcgc tgacgcgaaa gtcccgtccc tccggaggag
    13561 gcattccttt gtcgtcggcg accacgtccg agtccacgtc cgagtccacg atcgagtcca
    13621 cgatcgagtc cacgatcgat acgagtgcga cggccaccgg ggccgtcatc gatgaagccg
    13681 ggttccgtga cggcccgttc gcccggttcg cgcaggatct gcggaccgtg cggatcctgt
    13741 ggcggcggga gatggtgcgg ttcctgcgca accgtgcccg gctggtgatg gggctcgcgg
    13801 cgccgctgct gttcctgttc gtgctcggga acgggatcgg ttcggccggc ggcgctctcg
    13861 gcctctacca ggcgttcctg ttccccggca cgctgctgat ggtggtgcag ggcccggccg
    13921 tggccgtggg cacggtgatc atgtgggacc ggcagtccgg gttcctgcgg cagatgctgg
    13981 tcgccccggt acggcgcgcc gcgatcctcg cgggcatctg cctgggcggc gccaccaccg
    14041 gggccctgta cgcgcttccc gtcctggccc tcgccgggcc catgggcgtg ccctatcacc
    14101 cccggctgct cctgctcctg ggcgagatca ccctgctcgc cttcgcactc accgcgctgg
    14161 gtgtctcggc ggcggtgtgc atccggcgcc cggagacctt ccagatcgtg tccgggctgg
    14221 cgatggcacc ggccgtgctg ctgtccggcg cgctgttccc cgtaggcggg ctgccgtcat
    14281 ggctgggcat ggtggtacgg gccaacccgc tgagctacgg cgtcgacgcc ctgcgccgca
    14341 ccatgccgga cccggaaccg ggcggcgccg ccaccccgtc ctggttccac gccggcccgg
    14401 agtggtgggg ctgggccccg ccggtcctcc tggagctcgc cctcgtcgtc gtaccgtccc
    14461 tgcttctgct gactctggcc ggccgccgct tctcccgcat cgactgaaaa cggctcgccc
    14521 gtcccctcag cgacttcgac ggcgacggcc ggtcgccaag tccgtgtccg gcatcacgaa
    14581 cggcgcgccc ccgtcgccac caggggcttc gacggcgaca gcaggcagga catcttcggc
    14641 aaggggccgg gcgacgaacg ggccgccatc gtccacggcg acggcaaggg ccccggccgg
    14701 ggcgaggcgc gctccggggc cacgggaagg tgaaggtggg cctcgccgtc gcggtcggcg
    14761 aggcccacgc gacggccacg acgacgccgc gatccagtcg cgcggcggcg atcggcgcgt
    14821 cggccaggtg gtggggctgc tcggcagcga gggcgggctc agcgcggacc gtaccgtcac
    14881 gctcgaccgg taggcgatcg gcctcggtga ctcaccgtcg agcgcatgcg gcggcgacgc
    14941 gaggacgcct gttactggat cccgcgcggt acgcgggacg gcccctcgaa gacggaccga
    15001 cgctcgtcag gaccaaggac ttcggcagcg gctgaccacc cggcgctccc ggatgggcta
    15061 gtccgacgcg ctggagtctc ccgtgccgcc gaggctgagg gccaggaggt gaggcgggag
    15121 atgtccatga gtggtcgggc cgaggtggtc gtgcggccgt cgccggtgct gcgcatcgcg
    15181 gtcatcgggg actgccccct cttccggcac ggcgtctccc agctgatcgg taccgccccc
    15241 gacctccacc tggtcgccgc cgcagcgtcc atcgaggccg cggacggcag cctgcgcggt
    15301 gcggaagtgg tgctgatgga tctgcagcag tccgccccgc ggctcgccgc ggccgtggcg
    15361 aagctgcggc ggcaggggca tgccgtcatc gtcgtgtcgt cctctccacg ggtcgacgcg
    15421 gttcaggtga tccgggaggg tgccagcggc tacctgagcc gacaggccga gggggaggaa
    15481 gtactgacgg cgatccgggc cgtgggatcg ggccgcagct atgtgtgcgc gcccgccgga
    15541 cagctgctcg gaccgtcacc gcgcttcacg gaccgggagc aggagatcct ccgcctcgtc
    15601 gccgacggcg cgacggacca cgagatcgcc gctcggctga gaatcagcaa gcacaccgtc
    15661 cagtcgcatc tcgaccggat cggcgagaag acgggctccc gacgccgttc cgatctcacc
    15721 cggctcgccg tcgaatccgg gcttacggac gcggaacagc cggaataggg gcctgccgca
    15781 ttcctttcct ttcgcagtcc gctgtggtcc tttcgcagtc cgctgtggtc ctttcgcagt
    15841 ccactgtggg tagtcctacc cctccggttg tgggcaatga ttccccttga ccgaaacagg
    15901 ccgatgccag acctttgtag ggaaagcttg ccgccgcatc agccggaaaa gtggtcgttg
    15961 ttccgggcat gcggggcggt gatggctgca tgaaagcgct attcatccgt catttcgcag
    16021 ccgatcaagc gacgtcccac actcaggaga agcccatgcg caagcgtgta attctcgccc
    16081 tcgcggccgt gctccctctg accggggtgg ccacccttgc gggagcgagt caagcagcag
    16141 ccgacccgac gaagtccagg gtcgtggtcc agggcacggt cgaggactgc gaggacgaca
    16201 cggccccgct ccaggtgacg atcgagacga agaaggacga agtcggtgtc gacagcaaac
    16261 ctcgcgtaga ggacgaggga aagtacaagg tcaccttcaa gaacatcccc aagaacggtg
    16321 tcaaggccac cgccaccgtc gagtgcgaag aggattcgta cagcacgtcc ctcaccatca
    16381 agcgtccgcc cggaacgaag ctcactcaga ccttcaacat cgagccgtag ggtccctgac
    16441 aggcattcgg ccgggtctcg tccgtacgag acccggccaa cgcgcccttc gggcaagggg
    16501 gttcgcccgc ccccctcgta tcgactgacg gtcccggcga cgactcgcca cggtggctct
    16561 atatgatcgg cgttcgcatg tgcgggggca tgtggcgatt cggcatcacc gtgtacagct
    16621 ctgcgctgcc gtcttccctc tctccgtgcg tcgcgcccgc aaatgagaca tcgacgacga
    16681 acgagggaga tcaggggcaa tgtcctatcc cccgccgccc cagggcggcg cctggccctc
    16741 cgggcagggg cagtaccccg ggcaaccgca gtacccgggc atggcgccgc aatcgcagta
    16801 cccgggcgtg gcaccgcagc ccccgtaccc cggtacggca cctcagcccc aataccccgg
    16861 tacggcacct cagccccaat accccggtgc ggcaccgcat ccccaccagt acccggtacc
    16921 cccgccccga ccgggcggcg ttccgctgcc gccgcccaag agctcgggca cgggcctggg
    16981 ttgcctggct gccgtcctcg gtgtcttcgg cgtcctcggc atgctcggcg gcggcttcct
    17041 ggtcagccac gcgtactcga atcacagcca ggtcatatcg aacggcgggg agtacgggcc
    17101 gacgatgtgg cgcaacgaac cggcggacgc gttcttcccc gaggtgctgg cgcccgtgaa
    17161 cagcgccacg gagaacgacc cgaagcgggc cacctggcac cggctcggca tatccgagga
    17221 caccgggtgc gaggacgggc tcaacaaggt caccgcggcc gccgtgcggg acctggactg
    17281 cgaggcggtg ctgcgcgcca cgtacgtgga cccgacgggg aacaccgtgg ggacggtgtc
    17341 ggtgatcgtg ctgccggagg gcgggtccgc gcagatgacc gagttcttcg agaaggacgc
    17401 cgacaagctc gaccccgagg tcggcgcgaa gccgtacgcc gtgcccggca ccgtagcggc
    17461 caagtggagt ggggcgcgca gcaacggcgg ggcggggatg gaactcggcg gcatgccgta
    17521 cgtcctcgtg gcgtccaccg gcgccgtcga cggccggaag gcgggcgaac tgcccggcga
    17581 gtggggcagc cacagctggt ccgcgggaga tgaccgcgcc ccgtggcggg gcgccgcgaa
    17641 ggccctctgc gacgacatgg aagtgcacct gatgaacctg ctgagggaga cctcgtgatc
    17701 gtgcggcgta ccgccgtggc cgtggcggcg tccctgatcg gcctgaccgc gtcggcctcc
    17761 gcgtcgggta cggcgaccgc cgcgccccgc gcggccgaga ccgtcccgca gagctgggag
    17821 tactcggcgc tgaacctggc ccaggcccat cgggcggcgc agggcgaggg cgtcaccgtc
    17881 gccgtcctgg actccggtgt cgaggccggc cacccagccc tcgccggcaa ggtcaccacg
    17941 ggccccgact acgtcgagga cggcctccag ccgggcgacc cgaagtgggg cgaccacggc
    18001 accgcgatgg cctcggacgt cctcaaggtc gccccgaagg ccgagatcct ctcgatccgg
    18061 atcaccagcg acaaggacga ggacggcttc tacaggggga ccagcaggat cgcccggggc
    18121 atcgactacg cgatcgagca cggcgccgac gtcatctcca tgtcgatcgg cggcgaactc
    18181 ctcggcgaca gctacgacga ggacgaggcc gacgccctgg gccgcgccgc gcaggccggc
    18241 gttccggtcc tcgcctcggc gggcaacagc ggtgacgagt tcaacgacgc ccagtacccg
    18301 gcgggttacc cgggcgtgat cgccgtcgcc gcgctccagc agagcggcac ccgggccgag
    18361 ttctccaccg tgcggaccta caactcggtg gccgcgccgg gcgtggccat catgagcgcc
    18421 aagaacaccg gcggctacga ggcgatcaac ggcacctcac ccgcgacggc gctcagcgcg
    18481 ggtgtcgtgg cgctgatgaa gtcggcgaac ggcgacctga cctccgcgca ggtccgctcc
    18541 atcctgacga ggacggcccg ccacgcctcc tccggtccca gcccgctgga cggctacggc
    18601 atgatcgacg cggccgccgc cgtcgaatcc tccgcgaagc cccccgccga ccgcaccgag
    18661 cccatcgccc acaagggcaa ggaacacctg gccacccccg acggcacccc gaagacccaa
    18721 cacccgcctc tggacacgga actggtggcc atcggcggcg ccgcggccgc cgtaggcctc
    18781 gtcatggtca tcggcgccct cctgagcgcc agagcggccc gccgccgcgg gacccgcgcc
    18841 cgcgcacagc aggcggggca gggctgagcg gcaggttcgg atgcgttgtc gtccgcgggt
    18901 gagtgggggc ttgtggcaca gttccccgcg cccctgagaa gcaggggctg cgccccctgc
    18961 ttctcagccc gcagggccgt ggctttcagc ggcgcgggga actcgccgag cccgtcacca
    19021 ctcggaggcg agcgcctccg tcagtcgtgc ggcggcggcc gggtccggca ggctccgcaa
    19081 ggcggtgagg acctggtcgc tcgcgaactc gcgctgggcc ggggtcacat tcgggtcgat
    19141 cgcgcatccg gcctgtacgc ggacgtaatt caggtccgtc gcgaagagca tcgagaagga
    19201 gtcgagcccc ttgacgaccg cgggcccgcc ggcgtccaca taggcccgta ccagccgccg
    19261 ggcggagtcg gcgtcgaagt cgttcccacc cgcccataca tggacggcgc gggcgagttc
    19321 gcgttccgcc gatatgaggc cggcgttgtc ccagtcgaga agggcgggcc cggccgggcc
    19381 gaccaggacg ttctgcggcc gcatgtcgag atgggacacc accacgtcac cggcgccgga
    19441 aggggtgaca tggtccgcca gctcccccgc cgaggtggtg atgaaccgcc ccagctcgtc
    19501 cgcccacggc acaccggccc gccgcaccgc ctcgtacaac tccgcccagt cggcagggcg
    19561 cgggcattcc tcgtaccagg cgttcggctc cccgctcgct ccctccccgg cccggtgcag
    19621 cagggccagg gtccggccgc accacgccag gatctccggg tcggccggat ccgcctcgac
    19681 cccgtcgacc cagtcgtaca gcttcacgta cgacccgccc atcgaggagg gcagccgcga
    19741 gacgtacgcc ccggtgcggt ccggcaggaa ccggggcgcg gaaatcccca gcccctccgc
    19801 ggcgttccgc aacgcggcct cccgttgcac ctgcccctcg tcacagccga acagaagctc
    19861 cttcaccgcc cacgagaagc cgttccccga cgacaacttc cagatctgcc ccagcgcccc
    19921 ccgagcgacg ggcgtcatgt cccacgccgg ggagccgggc cccactccgc attcgccgcc
    19981 gaggccgtac atggtcgcga tgaaaccggc cctgctccgc atgcgctcac ctttccgccg
    20041 tggaaccaac aggttctcca gcttgccggg gcgcggcacc gcgcaggaac agggcactgg
    20101 tgagggtgcc gaggagcacg agcgcggcgt tcagggcgat cgcggccttg agaccgccga
    20161 gcatgaccgc ggcgccgccg ccggtggccg cggcggtggc gaccgcgctc atgatcggcg
    20221 tgcccatggt gataccgatc tgctgggtca tggtggcgag cccggtggcc aggccctgct
    20281 cgtggtcgtc gagcccggac gtggcggtga ccatgaaacc gacgatgacc agcatgttgc
    20341 cgacgccgcc cgcgaaggtg ccggccagca gcagccacat cgaggagcgg tcgtcgccca
    20401 tccccagcag ggcgaccgtg aagacggtct gaacgacacc accgacgatc agcgtccgcc
    20461 tgctgcccac cctgccgatg acccggggcg cgagcgtgcc gccgacgacc gtaccgaccc
    20521 ccagcacacc gaacgacagc ccagcggcca gcggcgagaa gccgaggact tcctggaggt
    20581 agagagtgag gaggaagacc agggaggtct ccgtcaggaa ggcgatcagc ccggccacgt
    20641 tcccccacgc gaccgaccgc ttcccgagca caccgaccgg caccagaggc tcggagaccc
    20701 ggcgttcgac gccgtagaag acgaggagca gaacggcacc cgccgcgagc cacagcagcg
    20761 cggacgccga gccccagccg tgttcgcccg cccgggtcag gccgaggacg acggccagca
    20821 gaccgagcgt gacgctgacg gcacccggca cgtccagcct cgggcgttcg tcgggccggg
    20881 actccctgat gacggtcggg gcgatgagga ggacggccag gaccacgggc acgttgacga
    20941 agaacgccca gcgccaggag agcagttcgg tgagcaggcc gccgaggatc gcccccgcgg
    21001 tgaaaccggc cgacatcagc gccccgttga gaccgagcgc cttctcccgc agcggcccct
    21061 cgggaaagga ggtcgtcagc agcgacagcc cggcgggcgt gacggcggcc gtggcgagcc
    21121 cctggaagac ccgggccacg atcagcacct ccgggtcctg cgcgagcccc ccgaccaacg
    21181 aggccgcccc cagcaccacc agtccgccga ggaacagccg ccgccgtccg aagaggtcgg
    21241 ccacccggcc gaagagcagc gtgcaccccg ccgcgcacag cgcgaacgac gtggcgatcc
    21301 actgcagacc cgccgacgag aaccccaacc cgtcgccgat caccggtagc gccacattca
    21361 ggatggagaa gtccacggcc agcatgaact gagccgcgag gagcagcacc agggtcagtt
    21421 tcaggcgggg agtgagcgca ccggtgtctg tgtcggtgtc cgtatccgta tccgtatccg
    21481 caatggacat gtcgtcgggt ccctttccct cgcgtgctcg cactcgctta ctcgcactcg
    21541 cttactcgca ctcgcttact cgcactcgcg tgctcgcact cgcgttccgc tacggagaaa
    21601 gaggctcgcc cgccccgaga accccagcca gaaccctgtc ccgcacaccc ggcgcgaggg
    21661 tggtcatcac agcaccaccc tcacggcacc cgcccgtcca tggccctgtg catcatggac
    21721 ggcatggtga acgccccgtc cgagctcggg gacttcctca ggtcccgccg agccgcgctg
    21781 cgccccgagg acgtcgggat cgccccgcac ccggcccgcc gccgggtgac cggcctgcgg
    21841 cgcgaggagt tggcgatgct cgcgggagtg agcatcaccc actacacccg cctggaacag
    21901 ggccgtgccc tgagcccctc ggacagcgtc ctggagtcga tcgcccgcac actgcgcctc
    21961 accgcggacg aggtcgccca cctgaagacc ctggcccgcc ccacgcctgc gccgccgtca
    22021 ccccgcgtgg cgcacgcgag tcccgccacc cgccggctgc tggccgccat gaccgacgta
    22081 ccgtccctcg ccctggaccg ccgcaacgac gtcctggcct ggaaccgcct cggccacgcc
    22141 ctcctcgccg cccatctggc accggaggcc ccggacaccc ccgccacgcg ccccaacctg
    22201 acccggatgc tcttcttgga cgaggcctac cgcgcgctgt tccccgactg gaccggggag
    22261 gcgggcctcg cggtggcctc gctgcgcctc gtcgccgggc gccgtcccga cgaccgtgcc
    22321 ctcgccgaac tggtcggcca actctccatg aactcccccg agttcgcctc cctctggtcc
    22381 cgccatccgg tccgcacctg cacctccggc accaagcacc tgcaccaccc cctcgtcggc
    22441 cggatgcacc tgaccttcga gaccctcgac atcccgggcc cctccgggca gcgcctcatc
    22501 gcgtacacgg cggagccggg ttcgccgtcc gaggcggcac tgcgacta
//
