LOCUS       NZ_NHRV01000001        28813 bp    DNA     linear   CON 21-AUG-2024
DEFINITION  Prevotella intermedia strain KCOM 1107 KB29_1, whole genome shotgun
            sequence.
ACCESSION   NZ_NHRV01000001
VERSION     NZ_NHRV01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Prevotella intermedia
  ORGANISM  Prevotella intermedia
            Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
            Prevotella.
REFERENCE   1  (bases 1 to 2010333)
  AUTHORS   Kook,J.-K., Park,S.-N., Lim,Y.K. and Roh,H.
  TITLE     Draft genome sequence of Prevotella intermedia KCOM 1107 (=ChDC
            KB29) isolated from a human subgingival dental plaque
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2010333)
  AUTHORS   Kook,J.-K., Park,S.-N., Lim,Y.K. and Roh,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2017) Korean Collection for Oral Microbiology and
            Department of Oral Biochemistry, School of Dentistry, Chosun
            University, 309 Pilum-daero, Dong-gu, Gwangju 61452, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2017
            Assembly Method                   :: SPAdes v. 3.8.2
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 566.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002204405.1-RS_2024_08_21
            Annotation Date                   :: 08/21/2024 03:55:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,359
            CDSs (total)                      :: 2,295
            Genes (coding)                    :: 2,240
            CDSs (with protein)               :: 2,240
            Genes (RNA)                       :: 64
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 20 of 55
            Pseudo Genes (incomplete)         :: 31 of 55
            Pseudo Genes (internal stop)      :: 12 of 55
            Pseudo Genes (multiple problems)  :: 7 of 55
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:05:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1336846
            Orig. end                         :: 1365659
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NHRV01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..28813
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="2"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..28813
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28813
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:18813](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..18813)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    134..150
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 21.05"
                     /tool="antismash"
     gene            532..2539
                     /gene="mobC"
                     /locus_tag="CBG55_RS05810"
                     /old_locus_tag="CBG55_05810"
                     /pseudo=""
     CDS             532..2539
                     /codon_start=1
                     /gene="mobC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004336024.1"
                     /locus_tag="CBG55_RS05810"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="CBG55_05810"
                     /product="conjugal transfer protein MobC"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAQEDDLRALGKVMDFMRGISVIFLLINCYWFCYEAFHVWGGYAW
                     HH"
     gene            complement(2593..2945)
                     /locus_tag="CBG55_RS13200"
                     /pseudo=""
     CDS             complement(2593..2945)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015365.5"
                     /locus_tag="CBG55_RS13200"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS1 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRCTFSSVKSHPRWLVYALDRETRKVVAFNVGRRPNRTLSAVLQS
                     LFLSKAKIIYTDKLKNYSYLTSRKIHRTVLPTISSGTILRFVST"
     gene            complement(2964..3140)
                     /locus_tag="CBG55_RS13205"
     CDS             complement(2964..3140)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024169.5"
                     /locus_tag="CBG55_RS13205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS1-like element transposase"
                     /protein_id="WP_198507510.1"
                     /transl_table=11
                     /translation="MTDHTYKAYLPNTDFKITRLTKEGLGIRSTARILGISVLPCLRGF
                     YRLRAISSSLLSL"
     gene            complement(3150..3290)
                     /locus_tag="CBG55_RS13210"
     CDS             complement(3150..3290)
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024170.5"
                     /locus_tag="CBG55_RS13210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS1 family transposase"
                     /protein_id="WP_198507503.1"
                     /transl_table=11
                     /translation="MTLQERFSTLYSRLGVEFQCPHCHSNNIIKSGKSSTGKQRYQCKH
                     C"
     gene            3531..4433
                     /locus_tag="CBG55_RS05820"
                     /old_locus_tag="CBG55_05820"
     CDS             3531..4433
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CBG55_RS05820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CBG55_05820"
                     /product="hypothetical protein"
                     /protein_id="WP_144264663.1"
                     /transl_table=11
                     /translation="MIKKILFASYISNIRDMYFGEYLVKFLINQKYSIKVISNKKYITG
                     FHNIYDDTISKKSNQYDLVLLHNKQAFKLINKMAITPPIFYLFNSDEIFKEQIEMNKYS
                     ELFLCGKPKILIDNSFYNLLNIYFDETFDDEQMKQEENIIIAESSMITINKLMPWLNTL
                     VSSNIYIISIKNHINSKYFNSNVHIVNNKNKIDRLFRNAKLIIADDQFAIKGIMLKKPV
                     LLLGSYGYGGLITNDNIDLLYKYGFTGRPGGNFDEHLPFELINYDFQEAYHLSDNELEA
                     AKMKLKNYLNIEYSTFIKK"
     misc_feature    complement(4599..4612)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.99"
                     /tool="antismash"
     gene            4701..6257
                     /locus_tag="CBG55_RS05830"
                     /old_locus_tag="CBG55_05830"
     CDS             4701..6257
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012745.5"
                     /locus_tag="CBG55_RS05830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBG55_05830"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_088438430.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.6e-08,
                     bitscore: 31.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQESSRINYHSSEIEDNSSFIHNFEVSVVMPFYKKLDEFKMVLP
                     KNQLFFQRNGIEVIIVMDEDSEENRLIKYIKRYPFINWKVIVNHDKHEWRNPSKAINVG
                     IRNASKDFIFVCSPESEFITDAIYIMRKKLEYYPAHFAIGTVSFTAIESYTELSNSIFI
                     EYGSIMAKKEAFYAVTGYDESLIKWGGDDDNIRVRLEMQGIKKILLPEVKLLHKEKPKE
                     LKSRNNKNIAIKTLKRIKCPLVIRANSKDWGKEFNDIAYSWEYKEIDEKVLYNYLKRFK
                     KFQLSKESLRKKFNSILLVQSYNEERNISLFLRRNSVYFDAIILLDDDSQDQTYSLAQN
                     PKIILKVKKERNFFNDIENRNTLLELVSFYNCKWICFLDVDELIDKRFCDFSFTQKNAY
                     NILFHTVHLWNSPKQYNVEYPYSNEGIQEHFRMFRNLGHMQILTNKKALHFPLTPYVKN
                     IYKSKILVLHYANICPKNRLERYKRYMKEDMALDQISYEHFLNNSPKLKEVKDIKIEHL
                     I"
     gene            complement(6752..7774)
                     /locus_tag="CBG55_RS05835"
                     /old_locus_tag="CBG55_05835"
     CDS             complement(6752..7774)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF027890.5"
                     /locus_tag="CBG55_RS05835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBG55_05835"
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_088438909.1"
                     /transl_table=11
                     /translation="MDNEIKRNNNIELYSEEVQEIMSKNPFWILRYGVIILLFIILTLV
                     VGSWFYKYPDIIKVNVIITSTNPPVTITARLTGNIDKIFVRNNQIVKAQTPLAVLHNTA
                     KNEDILKLIALLNQWQTKRDRNIINKQFISGQYLSLGSIQPYYATFVNSLNDYNNYLAV
                     KNCSQRRAIKYQLSVKNAYEALIAQINVWKQSYLMITPIEGIVNQIGVCRNNQNVNTGE
                     ALFTIMPLHQTCPEGKALLPINGAGKVKIGQRVNVHINNFPDQEFGYLIGKIKSISNIL
                     NKDGYYVVEIEFPNGLVTSYGNSLPTTQQMMGTADIITADLRLIERFFMPVKKLLSTNG
                     "
     gene            complement(7786..9996)
                     /locus_tag="CBG55_RS05840"
                     /old_locus_tag="CBG55_05840"
     CDS             complement(7786..9996)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007659803.1"
                     /locus_tag="CBG55_RS05840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBG55_05840"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_088438910.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 5.3e-32, bitscore:
                     107.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHPFPNYKQLDSMDCGPNCLRIIAKYYGKHYSLETLRQHSFITR
                     EGVSMLGISDAAEYIGFRTSGVMISFQQLAKDVPLPCILHWKQNHFVVVYKIIKDKRER
                     WRISVSDPALGLITYGESDFKKCWYSTKKNGKEMGAALLLEPSPEFFHREEEKDNHSRS
                     LRYFFHYLIPYKSQLLQLILGMLVISILQLIFPFLTQSLVDVGIRGGNLSFISLILIAQ
                     LVVFVSRLVVEFVRSWILLNMNTRINIAIISDFLAKLMKLPLRYFDTKMTGDIMQRIGD
                     HGRIEAFLTGNSISTLFSFINFLVFSFVLGYYNLAILGIFLLGNGFYVAWILFFMKYRR
                     ELDNKRFAQSAVEQSNIIQLITGMQEIKLNNSEKQKRWQWERIQVKLFKISIKSLTLGQ
                     LQQVGSVFFSQTTNIIISYIAAKAVVKGDISLGMMMSITYIVGQLSAPIEQFIGFVRAF
                     QDAQISLERLNEVHSKEDEEETIKNKLTILSDQKDISLENVSFSYDGADRNYVLDNVNL
                     NIPQEKVTAIVGASGSGKTTLIKLLLGFYEPNKGTIKIGETPLNLINPHLWRKKSGAVM
                     QDGFIFSDTIVQNIAVGEDNVNVENLSHAVTIANIRDYIDSLPLGYNTKIGAEGNGISQ
                     GQRQRILIARAIYKNPQFIFFDEATNALDANNEKEIMEHLRDFYKGKTVVVIAHRLSTV
                     KGADKIVVLDGGKVVEEGTHEELTMLKGKYFELVKNQLKLVK"
     gene            complement(10001..10885)
                     /locus_tag="CBG55_RS05845"
                     /old_locus_tag="CBG55_05845"
     CDS             complement(10001..10885)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03891.1"
                     /locus_tag="CBG55_RS05845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBG55_05845"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_088438431.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 9.3e-54, bitscore:
                     179.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSIIRTFIPGSEWLYFKIYAGEKTADKILTNEVYRFVHNLDKEK
                     CIFKWFFIRYADPDFHIRLRLLIDKEKISYIMSLFYKKFNSLVNKRIIWKIQLDTYNRE
                     IERYGSHLIQEAESLFCFDSNCVISILRQVNRSKNENYRWLISLEMVDSLLSDFSLDLA
                     SKKDFVEKCSESFRAEFGFNELNSKQLNTKYRENKKLIELVLTGNLNEADFKKCEIPIF
                     KRSIMLKPIVINIKKKLLNNRTLLLSNLLTSYIHMMIDRIFLSDNRVHELVIYDFLRRY
                     YTSIIQRNKYNKR"
     gene            complement(10882..13062)
                     /locus_tag="CBG55_RS05850"
                     /old_locus_tag="CBG55_05850"
     CDS             complement(10882..13062)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.5"
                     /locus_tag="CBG55_RS05850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBG55_05850"
                     /product="lantibiotic dehydratase family protein"
                     /protein_id="WP_088438432.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.2e-147,
                     bitscore: 488.5, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKAFQKFIFRSPLLPFQSVKDALEGEGALFKILSDNKILEAIFL
                     ASPVLYTEIKKLLANNIKNDSERERIINSVVRYISRMSTRCTPFGLFAGCGLGTFGKET
                     QISLKDARSRKTRLDMQYLCNLYNFITKETELKKKIKYYPNSSIYKVGSNIRYIETLYS
                     GATRKYQISEVEGSTYLEEILIKAKNGYTIKDLVNFLCELCEHNISIEDGYNYINELID
                     SQLLVGELSQSIIGDDFLERLINLIEKCGEEGSLLYSLKQIRDLLIELDTTLSNHYQIY
                     NEIISIIKSIDVPFEEKYLFQVDSFLLSHQATLNEQIIIDLQNCMLFLNAISRDNNETL
                     NHFKHDFFERYEEREIPLLEVLDPDIGLGYPSKMGGSNISPIIDDLYIPNTSGEKSFVL
                     TAFQSFMLDKIVNTKGDKKKEIIFTEKDINQSLKEEVNLPSTIYTLLKVIKNDDNNQLI
                     ALNSFNGSSGANLLGRFAHLQPDLERSVREIVNKEKELFPEKILAEIGHLPESRIGNIL
                     ARPHIRDYELLYMATSDLNSDKLIYLSDVTLSLKHNKLTLNSNKKEIIPRLTTAHNFHN
                     PQLMPVYRFLCDIQAQEGGGIFFSWGKLDEMFSFLPRVRFNNIILSPAQWNIKTDDIKA
                     IFSRKSDKEILSSINEWRKGIDLPQEALLADGDNELYVEFENIYSVKAFYSIIKRRNRF
                     RLKEFLFDKQNALVKSEEQPYLSECIISFYKQ"
     gene            complement(13188..14363)
                     /locus_tag="CBG55_RS05855"
                     /old_locus_tag="CBG55_05855"
     CDS             complement(13188..14363)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.5"
                     /locus_tag="CBG55_RS05855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBG55_05855"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_088438433.1"
                     /sec_met_domain="LANC_like (E-value: 5e-45, bitscore:
                     150.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRLYNDFDNLRFTLITKIKDALLNNQEQDNCGLMGGTVGELLFL
                     LYYYDLTKEQYIPDYIFSKLDKIITMSNSYNKIGYSFSHGLSGIGWFIDVVKRKGLIDS
                     SSNDVFGSVDEIIFNHSLEDLKFGYYDYISGSLGALVYFLRKENPPIHYIKQYLEVLDQ
                     IKQSKGNHFFLYENEKKTSCNLGLSHGIPSIIAILLIAYEKKICTSISHNLINGFVEFL
                     LSNMHTPENKGNTYFSYSTDSPTRSTRLAWCYGDLGIGYILYKTSIMMGDSHLKAKALE
                     ILSYTAKRFDPIQNWVFDACLCHGSAGIAYIFQKVYNLSNDRIFADTSEYWYQKTIELG
                     SNPDGIGGYLFQKKGLKLPIRGILEGVAGVGVSFISAYHEVDTAWDEILLL"
     gene            complement(14710..14949)
                     /locus_tag="CBG55_RS13215"
     CDS             complement(14710..14949)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038153.1"
                     /locus_tag="CBG55_RS13215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I lanthipeptide"
                     /protein_id="WP_198507504.1"
                     /transl_table=11
                     /translation="MKKLRKLVLKKDVITSLGKTEQANLKGGMSAGCSDGCLSAWGHTR
                     IWNCSKADCTHDCGHCGDPTWTASGDCPTLRCQV"
     CDS_motif       complement(14878..14949)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKLRKLVLKKDVITSLGKTEQAN"
                     /locus_tag="CBG55_RS13215_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14710..14877)
                     /prepeptide="core"
                     /locus_tag="CBG55_RS13215_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-14.60"
                     /molecular_weight="5578.2"
                     /monoisotopic_mass="5574.4"
                     /core_sequence="LKGGMSAGCSDGCLSAWGHTRIWNCSKADCTHDCGHCGDPTWT
                     ASGDCPTLRCQV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKLRKLVLKKDVITSLGKTEQAN"
                     /leader_location="[14877:14949](-)"
                     /alternative_weights="5596.2"
                     /alternative_weights="5614.2"
     gene            complement(15174..15950)
                     /locus_tag="CBG55_RS05860"
                     /old_locus_tag="CBG55_05860"
     CDS             complement(15174..15950)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009236196.1"
                     /locus_tag="CBG55_RS05860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBG55_05860"
                     /product="ABC transporter permease"
                     /protein_id="WP_013264619.1"
                     /transl_table=11
                     /translation="MKPISFFTILKSEHYKLRFNIAIWLFLLFPLFMTLCIDIYVLFKH
                     ADAVNNPTITFDYNPWVWVLGRYIFDFYALLYPILAAILSYSLCDVEYKNYGFRLLFTR
                     PISKLTIYSSKMVFLLEINFISFLIGYLAFLLSGFALDKLLPGYEFSSYNVNNLTAFYF
                     SYLFIALSAVSIMQYYLSLIFKSFVLPIGFAGFMTIFGVIAQNKDYIYLIPYGTVWRLN
                     YGFYSGIIDFSKGEYLNISCVLFFIIISFFVFIRKK"
     gene            complement(15947..16849)
                     /locus_tag="CBG55_RS05865"
                     /old_locus_tag="CBG55_05865"
     CDS             complement(15947..16849)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013263868.1"
                     /locus_tag="CBG55_RS05865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBG55_05865"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_088438434.1"
                     /transl_table=11
                     /translation="MNILETNHLTFNYINHSVLEDINLKIPEGSIYGYLGKNGEGKSTT
                     IKILLGLEQTKINTVFFNKKEFHSNRLHILQNIGCLIEHPFFYADLSAYENLNYLDILY
                     HCGQKRIQEVLELVNLTKDKDKKVRKYSTGMKQRLGIAMAMFHNPKLLILDEPLNGLDP
                     QGVFEMRELMLKLKSKGITIFISGHILAEMEKICTHIGILNNKRLLFQGEINSLLNQKK
                     QSYLIHTDQPERCMKICKEHLIPTKRISDGTLIIEIEQDGSFDSFKKLMQQNHIQILFA
                     DTYQENLESVFLHLIKTDL"
     gene            complement(16871..17650)
                     /locus_tag="CBG55_RS05870"
                     /old_locus_tag="CBG55_05870"
     CDS             complement(16871..17650)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021616.5"
                     /locus_tag="CBG55_RS05870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBG55_05870"
                     /product="galactosyltransferase-related protein"
                     /protein_id="WP_088438435.1"
                     /transl_table=11
                     /translation="MKINLKDTTFVFVIRLDSIERLENLLIVIFNINKYFDTNIAIIEG
                     ANHNNSILASLLPRKVSYTFVNDMDDIFHRTVYYNRLTRENNTPIIAIWDSDTIIDKKS
                     IMEAVNILRSRQADIAYPYNGIVYQTSDILRRYYLNTKDIKVLYKNLNKLDFLYNQPMY
                     GGAVFVNRNKYIDAGMENERHYGWGNEDYDSYNRFKNLGYNIYRVDTPLFHLCHPRKEN
                     SSFRSKIFHQISSNELYRISNSSKEELQDYIKSFKYE"
     gene            complement(17647..18813)
                     /locus_tag="CBG55_RS05875"
                     /old_locus_tag="CBG55_05875"
     CDS             complement(17647..18813)
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.5"
                     /locus_tag="CBG55_RS05875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBG55_05875"
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_306425387.1"
                     /sec_met_domain="LANC_like (E-value: 1.3e-07, bitscore:
                     27.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISHLVLHLQSVKLCKTSLFSNIFLTFVKSITYLQFSSCVFIIYH
                     KSKKQSMNRLLINCINNRLKNSLNDSEHSLGLFGGKMGLCIYFYMLDYRKSNKNFKVIA
                     EKLLEQVISQLHTIKSIDIENGLAGIGLAISFLLKKDIIKGNVNTVLSDIDDEIFKQIS
                     FRNFDKDPKTLIQILFYIYIRKESTSGELDYFFNELSIYIINLLHSHCEHFIEKSDTTF
                     SIYTQLPLFLYALGKVYEQNVYNIKIKKIIYEITPFIISKNPPLDSIKLQLIWGISSVN
                     QQIKNIKLSHYCNFLASQINIEVLINEFYDKNMFFEHGLAGIALLMVTLPSAIKQQINT
                     NLFFEKFIDKINESAIWKLNDSDLSKINLGLFGYTGVILITNLAEELV"
     gene            complement(18931..19167)
                     /locus_tag="CBG55_RS05880"
                     /old_locus_tag="CBG55_05880"
     CDS             complement(18931..19167)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CBG55_RS05880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CBG55_05880"
                     /product="hypothetical protein"
                     /protein_id="WP_088438437.1"
                     /transl_table=11
                     /translation="MVINRKFQNSKCAEDVNKAVIEELGHIKKYVKSITADNGPEFIRF
                     HELESALNTKIFFLPKKLIDILSCSLDNIFQNG"
     gene            complement(19734..22646)
                     /locus_tag="CBG55_RS05885"
                     /old_locus_tag="CBG55_05885"
     CDS             complement(19734..22646)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009236193.1"
                     /locus_tag="CBG55_RS05885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBG55_05885"
                     /product="hypothetical protein"
                     /protein_id="WP_088438911.1"
                     /transl_table=11
                     /translation="MKQLLGILLCMMLALPQQSFAQQPSPTSKKTRDMKMYGRVVDSFT
                     NLTIIDSKITLMTLDSTVVDTCSTQAWNKNAVHPESYFFMTPKVSEGKYIIKVENPKYE
                     TTYYSQEISFKTRATMIDLKDLALKRKRMEEIEHTLGEVVVKSTKIKMINKGDTIIFNA
                     DAFNLPEGSMLDVLIRQLPGATMNSNGEIFINGRKLDYLTLNGKDFFKGNNKQLIENLP
                     NYTVKDLKVFEKSTEKSQAMGIDVEKKDYVMDIQLKKQYERNFIGNADIAGGTNSRYAL
                     KLFSLYFTPHMQVSTFANINNVNEDRKPGEKGDWNPTKLPKGQVTMKTIGLNLANSNEK
                     NTVSNSLSTSVSWINTHNVTHAAAESFLGTANNNFTRRINNSTAKNAIYELNDQFRVNK
                     SYQLMAFLRLNYNKFDNFSTDKSATFQTSPRSLGSTEAILDSAFTVPLQRLSTYKSVNR
                     QLSQSLGNGHTLSSTLETYLGKPLKSGDRIGIQASSTYEKIKNYTFSKYQLDYLQDTGG
                     KDYRNRHDESPSYTYSYKLEPQYIFVLPSGFNIFTGYEYRQAGNYRNNNKYRLDRLQEW
                     KNEDHSIGSLPSTWDSLLRSLDLNNSYTGYYMSKQHTGTIGVHYMKRKGKETFVFGIFV
                     PLSYKKEQLDYRSEPITKLVSQNNWIKQINFSGQLIRNEYQFIMWGNSTTTTPDMYSLI
                     DRRDDSNPLAISLGNPNLKNGIQSSLGIRFSDNHNSRYKLPSINLDIQGTHNAVANGFI
                     YNPQTGVYTYKPENVNGNWSAHSGIYYNVPLDSMKYFNLFTETEYNYNHNVDLAGVAGQ
                     TRSVLSKVNNHITRQYLEVKYQKGNLSWSLMGQLSWRNVNSARENFITLNTYDYEYGFI
                     GSYSMKSGLKMGMDLKMFCRKGYADEQININNLVCNAYVSQSFMKGKFAVKFEAFDLFH
                     KLKSVDYQVNGQGKSEIRYNTIPHYIMLHAIYKMNVRGKK"
     gene            22884..24290
                     /locus_tag="CBG55_RS05890"
                     /old_locus_tag="CBG55_05890"
     CDS             22884..24290
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004353640.1"
                     /locus_tag="CBG55_RS05890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBG55_05890"
                     /product="DUF4099 domain-containing protein"
                     /protein_id="WP_088438438.1"
                     /transl_table=11
                     /translation="MESNNNDYVLVLEDRTEVESVNETGKLSVVSSIDDKGNLKTTEAV
                     AANQVAFLKFNSKDGLLKNFMANFLKQFNNPTHFGLYKVLADNVEQGVDNLRTLLQSRE
                     KPESKQQLAEMGVPFEDYLPQQKNATAIDESKIDWKQLDNLGLSRERLEQNGELEKMLN
                     WQKSNLITIAVPIGGTTIYTEARLAFRTDDSGNIGLAIHPLRKEPQLDFPYMGYKFSPE
                     EKEALLTTCNLGKTIEVTPKNAEPFSAYVSIDSQTNEIIALRADRVNIPKEIKGVTLSD
                     TQYKDLVEGKAVKVEGMTAKSGKSFNATLQVNAEKKGIEFIFGDNKSLRERQEHKQAQQ
                     QGVPHKLCGLELSEKQREALDSGRTLYLKNMVDKQGQSFNAYVRMDKEQNRLRFYKWNP
                     DKKQETGKEKVVAVAEEHKTQVAVNNHGKTNEATKNVKEPLKTGQTQPTSEQKQKQDEN
                     KQKKSRGRKM"
     gene            24312..26375
                     /locus_tag="CBG55_RS05895"
                     /old_locus_tag="CBG55_05895"
     CDS             24312..26375
                     /EC_number="5.6.2.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009228524.1"
                     /locus_tag="CBG55_RS05895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBG55_05895"
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_088438439.1"
                     /transl_table=11
                     /translation="MTTCIIAEKPSVARDIARIVGANSKQDGYMECNSYLVTWAMGHLI
                     ALAMPEAYGFSAYKAEDLPIRPNPFQLVVRQVCKNKEYISDPAALKQLKVIRSCFDKAD
                     RIIVATDAGREGELIFRYIYQHLGCRKPFDRLWISSLTDKAIREGLSNLKPGSHYDNLY
                     YSAKARSEADWLVGINASRALSIARKGGYSLGRVQTPTLAMVCRRYIENRDFSSVPFWK
                     LSVLTEKEGLSLKAIGITDYESEASAQTALATLRSQSRLTVESVARQVGHTAPPLLYDL
                     TALQKETNRRHGFSADKTLSIAQSLYEKKITTYPRTGSRYISEDVFEEVPALLHKIGKP
                     LSNPLNRHSVDNAKITDHHAIIPTGETPSGLLTDEAILYNMVVTRFIEAFSPDSEEERM
                     QVLFTDGTNTFTWKACRQISLGWKAVQKEVKSDDEEELLATLPNLTEGELLPLLNAEIT
                     EHKTKSKPLYTEATLLSAMENAGKEVEDAESKKAMAECGIGTPATRANTIETLILRDYI
                     RRDRKSIIPTEKGLAVYEIVKDKKIANAEMTGSWELALAAIEAGKMPSDKFSQGINSYV
                     GTICEELLSLSSEQKSYPVYRCPKCGQKSVGIYAKVAKCRHETCGFHAFREVCGIHLSE
                     DNIRDLIGSGRTPILKGLTSKAGKKFNARLVLGEDYTTSFEFENKKGKQRGR"
     misc_feature    27231..27247
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.1"
                     /tool="antismash"
     misc_feature    28565..28579
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 16.27"
                     /tool="antismash"
ORIGIN
        1 gaagaaaggt attggaagta atgcgtactt ctccccaaac ggaggaaaga cttcgacaaa
       61 gattggagga acaaggcttg cgggtagtta tccgaaagaa tgagggtgga cgcatctatg
      121 gtattacatt cattgatgat gaaaaaggca ttgcgctcaa tggctctcga ttgggtaaag
      181 gatatgccgc caataagttt aacgagtact tctctaacct agagaaaaat ccattcttgg
      241 atgaatcgct ttatggtagc ccgtccgttt gccatgaaca gacaaataat atacggtcat
      301 tgcaacagga cacagaggaa agcgacaatc ttgtcgatga acttattgac gatatgatgg
      361 gagaaacttt ctctacatcg ggcaatgatg attggaaaga agcggtatgg caacgcaaac
      421 tgcgcaaaca aagtaaggta aaacttagac gaagaaaaca ttaaataaac gagcatttct
      481 atctcccctc ccttcggagg gggttggggg aggctacaaa aacattgcat tatggcacaa
      541 gaagatgatt taagagcatt gggtaaggtc atggacttta tgcggggtat atcagtgata
      601 tttctcctta tcaactgtta ttggttctgt tacgaggcat ttcatgtctg ggggggttac
      661 gcttggcatc attgataaaa ttctaatgaa cttccagcgc accacgggct tgttttcatc
      721 catcctctgg tcaaaactct tttgcgtggt ttttcttgcc ctctcctgct tagggacaaa
      781 gggtgtgaaa gaggagaaaa tcacgtgggc aaagatttgg acggtgcttt tcttaggctt
      841 tgtctttttc tttctcaact ggtggctctt ggctttgccc atcggcaagg tcggggcagc
      901 ttccctctat atatttacgc tttccgttgg ctatatctgc ctgttgatgg gtggcgtatg
      961 gatgagccga ctactcaaaa acaacctgat ggacgatgtg tttaatactg agaatgagag
     1021 tttcatgcag gaaacacggt tgatggaaaa tgaatactcc gtcaatcttc ctacacgctt
     1081 ctactataag aagaaatgga acaagggttg gattaacgta gtcaatccct tccgtgcctc
     1141 aatggtgctt ggaacaccag ggtcgggtaa gtcctacgct atcgtgaaca attacatcaa
     1201 gcagcagatt gaaaagggct ttgcgatgta tatctatgat tataagttcc cagacctttc
     1261 cgagattgct tataatcacc tgcttcatca tttggatgtc tacaaggtaa aaccgcagtt
     1321 ttatgtaatt aactttgatg accctcgaag aagccatcgt tgcaatccca tcaatcctgc
     1381 ctttatgacg gatatatcgg acgcttacga aagtgcctac accatcatgc tcaacttgaa
     1441 ccgctcgtgg atacaaaaac agggagattt ctttgtggag tcgccgatta tcttattggc
     1501 agccatcatt tggtttctga aaatctatga gaacggaaag tattgtactt ttcctcatgc
     1561 catcgagttc cttaaccgtc cctacgcaca gatattcccg atactcacct cctacgatga
     1621 acttgccaac tacctttcac cctttatgga tgcttgggaa ggcggagcac aggaccagtt
     1681 gcagggacag atagccagtg ccaagatacc gctatctcgt atgataagcc ctgcccttta
     1741 ttgggtgatg acgggtgatg atttttcact tgatattaac aatcccaatg agccgaaagt
     1801 ccttgttgtg ggtaacaacc ccgaccgcca gaatatctat tcggcagctc tcggtctgta
     1861 taatagccgt atcgtgaagc tcatcaacaa aaagaagcag ctcaaatcct cggtgattat
     1921 agacgagctg ccgaccattt atttccgtgg gttggataac ctcatagcca cagctcgaag
     1981 caacaaggtg gcagtatgct tgggcttcca agattttagc caattaacaa gggactatgg
     2041 cgacaaggag agtaaggtca ttcagaacac cgtgggtaat gtattcagcg gtcaagtcgt
     2101 gggcgaaaca gccaaaacac tcagcgagcg cttcggtaag gtgctccagc aacggcagtc
     2161 tatgaccatc aaccgcaatg acaaatccac gtctatttcc actcagatgg atagccttat
     2221 cccagccagc aagattagta acctcacgca ggggatgttt gtgggtgcgg tatccgacaa
     2281 ttttaatgaa cgcatctgtc agaagatttt ccatgcagag attgtcgtgg atagtgctaa
     2341 gatatcaaca gaaatgagag actaccagct cattcctgta atggcagatt tccaaaacga
     2401 agatggctct gataatctca aagaaactat cgaagccaac tatagcaagg taaagcaaga
     2461 aatactattg cttgttgatt cagagattca aaggataaaa aacacccctg cattggccca
     2521 tctcattcca gacaagtagc gcaaccaagt atcgaacgtt gtggatgtgg tgtgatggtt
     2581 taaggaacag agctataccc acaggtaaat cctaatgatt gccgtcaaca ctgataaact
     2641 acggctgtaa caaatcgttt ttcggtttat tcgtttcagg tggatacgaa gcgtaagatt
     2701 gtgccgctcg atatggttgg tagaacggta cgatgtattt ttcggctggt gagataactg
     2761 tagtttttca gtttatcggt gtaaattatt ttggctttgg acagaaaaag actttgaagc
     2821 acagcagaca gagtacggtt gggacgtcta cccacattaa aagctacaac cttgcgagtt
     2881 tctctatcca aggcgtacac caaccagcgc ggatgacttt ttaccgatga aaatgtgcat
     2941 ctcatccact ttgtagatct tgcctacaga gataggaggc tgcttgatat tgctcgcaat
     3001 ctgtaaaatc ctcttaagca aggtagtact gaaataccca atattcgtgc cgtactgcga
     3061 atgcccaatc cctctttggt cagtcgagtg attttgaaat cagtgttagg aagataggct
     3121 ttgtatgtgt ggtcggtaat aaaacgcttc tagcaatgtt tgcattggta gcgttgttta
     3181 cctgtactac ttttaccact tttgataata ttgtttgagt ggcaatgcgg acattgaaac
     3241 tcaactccca atctggagta taaagtactg aagcgttctt gtaaggtcat ttttttcttt
     3301 gttttgggtt acaaaaatag caaaatacat agaatttatc cctgactcta cgcttaatcc
     3361 ttaaaaatcc attgatattt tgataactcc cgatctagag cattacccaa tataaaatta
     3421 aatgattaaa gtattaaaaa tactatagga tataaattta aaaaaaaaat gtatatttgc
     3481 aatgcacgtg aaaagactat atttctataa ttaaatttaa atccaaactt atgataaaaa
     3541 aaatactttt tgccagctat atttcgaata tcagagatat gtattttggt gaatatcttg
     3601 ttaaatttct aattaatcaa aaatattcaa ttaaagtgat aagtaacaaa aaatatatca
     3661 ctggatttca taatatttat gatgatacta tatctaaaaa atcaaatcaa tatgacttag
     3721 tattattaca taataaacaa gcatttaaac taataaataa aatggcaata acacctccca
     3781 tattttattt attcaacagt gatgagatct ttaaagaaca aattgaaatg aataaatatt
     3841 ccgaattgtt tttatgtgga aagcctaaaa ttctcataga taatagtttc tacaatttat
     3901 taaatattta ttttgatgaa acttttgatg atgagcaaat gaaacaagag gaaaatatca
     3961 tcatagcaga aagcagcatg attacaatta ataaattaat gccatggcta aacacactag
     4021 tatccagtaa tatttatatt atatcaataa agaatcatat caattcaaaa tactttaatt
     4081 ctaatgtaca tattgtcaat aacaaaaata aaatagaccg attatttaga aacgctaaat
     4141 taattattgc agatgatcaa tttgcaataa aaggtataat gctaaaaaaa ccagtgttac
     4201 tacttggttc ttatggatat ggtgggctta taaccaatga taatattgat ttattatata
     4261 aatatggatt caccggaaga ccaggaggga attttgatga acatttgcca tttgaattaa
     4321 taaactatga ttttcaagag gcttatcatc tttcagataa cgaattagaa gcagccaaaa
     4381 tgaaattgaa aaattattta aacattgaat attctacatt tataaaaaaa tagactttta
     4441 tatagaaatt aatcttaaca aaatacagaa atatacgcta gttataaatc caatgttttc
     4501 agtaatacaa gtcaatgcta caaaaacttt ttatctaata aataacataa catgtcaatt
     4561 tttgtatgaa ttgacggaag aagaatccat atatttagat ttttttaaaa atccacattt
     4621 aataaaagac ttcaaacatg atatttatag aataaatata gaaattataa aagaatttat
     4681 ttcatcaaag atattaattt atgacacagg aatctagcag aataaattat cattcttcag
     4741 agatagaaga taatagtagt tttatacata attttgaagt tagtgtagta atgccatttt
     4801 acaagaagtt agatgaattt aaaatggttt tgcctaaaaa tcaactcttc tttcagagaa
     4861 atggaattga ggtaattatt gtaatggacg aagatagcga agagaataga ttaattaaat
     4921 acattaaacg ataccctttt attaattgga aagtaattgt taatcatgat aaacatgaat
     4981 ggagaaatcc ttcaaaagct ataaatgtag gtataagaaa tgcgtccaaa gattttattt
     5041 ttgtgtgttc acccgaatcc gaatttatta cagacgcgat ttatataatg cgtaaaaagt
     5101 tggaatatta ccctgctcat tttgctatcg gtacagtatc ttttactgct atagaaagct
     5161 atacggaatt atcaaatagt atctttatcg aatatggtag tataatggca aaaaaggaag
     5221 ccttttatgc tgttactggt tatgatgaat ctttaataaa gtggggagga gacgatgata
     5281 acatacgagt tcgtttagag atgcaaggaa taaaaaagat tttacttcct gaagtaaaat
     5341 tattacataa agaaaagcct aaagaattga aatcaagaaa caataaaaat atagcaatta
     5401 aaactttaaa aagaataaaa tgtcctcttg ttataagagc aaattctaag gattggggaa
     5461 aagaatttaa tgatatagcc tattcatggg aatataaaga aatcgatgag aaagttttat
     5521 ataattatct gaaacgattt aaaaaatttc aactttcaaa agagtcttta agaaaaaaat
     5581 ttaattcaat tttattggtc caaagttata atgaagaaag aaatatatca ttatttttaa
     5641 gaagaaattc tgtatatttt gatgcaataa ttttactcga tgatgatagc caagaccaaa
     5701 cttattcatt agcacagaac cctaaaataa ttttaaaagt aaagaaagaa cgtaattttt
     5761 tcaatgacat agagaacaga aacacattgt tagaattagt ttctttttat aattgtaagt
     5821 ggatatgttt tttggacgta gatgaattaa ttgataagcg tttttgcgat ttttcattta
     5881 cacaaaaaaa tgcttataat atactattcc atactgtcca tctttggaat tctccaaagc
     5941 aatataatgt tgaatatccc tactctaatg aaggtattca agaacatttt cgcatgtttc
     6001 ggaatctagg tcacatgcaa atattaacaa ataaaaaagc tcttcatttt ccattaactc
     6061 cttatgtaaa aaatatatat aagagtaaaa tacttgtctt gcattatgct aacatttgtc
     6121 caaagaatag gttagaaaga tacaaaaggt atatgaaaga agacatggcg ttagatcaaa
     6181 taagctacga acatttttta aataatagtc ctaaattaaa ggaagtgaaa gatatcaaaa
     6241 ttgagcattt aatataaaag aatttgaatc tatacaacta tattattatg agttctttta
     6301 tctaataaaa tacttctaaa agtgattaaa attccttctt tcctaatatg agataaaaag
     6361 agtactaaaa tatttacaat aaatgtaata gcagaatagt ttaatacgaa aaagattcag
     6421 agtaaactta agaggtattg ttgataggag attcttcagt tttaggtaaa gtatgctata
     6481 tggtgtcctc gctaaatttc tactgacccc atatcactct aaaatgcccc acaagatagg
     6541 atactcaaaa attattcgaa aaattggcgt aaaatcccac aagcctagaa aataataggc
     6601 aaatgggact ttttaagata ctttttcata tacacagaaa tatttagcat cctacctata
     6661 agaattttgt ggctcataaa ataatcaccg aaaagatgaa tgtatacaac atttcactga
     6721 aatatgcttc ataaggaatc tctaattatc ctcagccatt ggttgacaat aactttttca
     6781 caggcataaa aaaacgttct attaacctta aatcagcagt aataatgtcc gcagttccca
     6841 tcatttgttg agtagtagga agggagtttc cataacttgt taccagtccg ttaggaaatt
     6901 ctatttctac aacataatag ccatctttat taagaatgtt cgaaatactt tttattttgc
     6961 caattaagta tccaaattcc tgatcgggga aattgttaat atgaacattt actctttgcc
     7021 caattttcac ctttcctgct ccattaatag gaagtaatgc ttttccttca ggacaagttt
     7081 ggtgtaaagg cattattgta aaaagagctt ctccagtgtt gacattctga ttattacgac
     7141 acactcctat ctggttaaca ataccttcta taggcgtaat cattagataa ctttgtttcc
     7201 atacattaat ctgagctatt aatgcttcat acgcattttt aactgaaagt tgatatttaa
     7261 tagctctcct ttgagaacaa ttcttaactg ctaaataatt attatagtca tttagactat
     7321 taacgaaagt agcataataa ggttgaatac ttcctaaaga taaatattgg ccactaatga
     7381 attgtttatt aattatattc ctatcccttt ttgtttgcca ttggttcaga agagcgatta
     7441 atttcagaat atcttcattt tttgcagtat tgtggagaac agccaaagga gtttgcgctt
     7501 tgacaatttg attatttcta acgaatatct tatcaatatt tccagttaat cgggcggtga
     7561 tagttacagg tggatttgtg gatgttataa taacatttac ttttattata tctggatatt
     7621 tgtaaaacca acttccaact actaatgtca atattataaa taaaagaata ataaccccat
     7681 atctaagtat ccaaaaagga ttcttactca ttatttcttg tacctcttca ctgtaaagtt
     7741 caatattgtt gtttctttta atttcgttgt ccatacttag ccccattatt ttaccaattt
     7801 taactgattt tttaccaatt caaaatactt tccttttaac attgtcaatt cttcatgcgt
     7861 tccttcttct accactttac ctccgtccaa cactacaatt ttatccgcac cttttacagt
     7921 gcttaggcga tgtgctatga ccacaactgt cttaccttta taaaaatccc gtaagtgctc
     7981 cataatttct ttttcattgt ttgcatccaa cgcattcgta gcttcatcaa aaaaaataaa
     8041 ttgcggattc ttatatatgg ctctggcaat caaaatgcgc tgacgctgtc cctgactaat
     8101 gccgtttcct tcggcaccaa tcttcgtgtt ataacccaac ggaagagagt ctatataatc
     8161 tcggatattc gcaattgtta ctgcatggct taagttttca acatttacat tgtcctcacc
     8221 tacagctata ttttgtacaa tggtgtctga aaaaataaat ccgtcctgca taactgctcc
     8281 agattttttc ctccataaat gtggattgat aaggtttaac ggtgtttcac ctattttgat
     8341 tgtacctttg tttggttcat aaaatcccaa gagcaattta attaatgtag tttttccact
     8401 accgcttgca ccaacaatag ccgtaacttt ttcttgtgga atatttaggt tgacgttatc
     8461 taacacgtaa ttacggtcgg caccgtcgta actgaatgaa acattttcca aggaaatatc
     8521 cttttggtct gagagaatgg ttaatttatt ctttatagtt tcttcttcat cttccttgct
     8581 atgtacttcg tttagacgct ccaaactgat ttgagcatct tgaaatgcac gtacaaaacc
     8641 aataaattgt tctatgggcg cagataattg accaacaatg tatgttattg acatcatcat
     8701 acccaatgat atatcccctt ttacgactgc tttagcagca atatatgaaa tgataatatt
     8761 agttgtttgg ctaaaaaata cggaacctac ttgttgaagt tgtccgagcg ttaaactttt
     8821 tatactaatc ttgaacaatt tgacttgaat acgttcccac tgccatcgct tctgcttttc
     8881 actattattc agctttattt cctgcattcc agttataagt tgaatgatat tactttgttc
     8941 aacagcagat tgagcaaacc gtttgttgtc caactcacgt cgatatttca taaaaaagag
     9001 tatccaagca acataaaacc cattcccaag caaaaaaata cccaaaatag ccaaattata
     9061 atatcccaat acaaatgaaa aaacaagaaa attgataaaa gagaaaagag tactaattga
     9121 attaccggta agaaaagctt ctatacgacc gtgatctccg attcgctgca tgatgtctcc
     9181 agtcatttta gtgtcgaaat aacgcagtgg caatttcatt agtttggcta aaaaatcgga
     9241 gattatagca atatttattc gtgtattcat gtttagtagt atccagctcc ggacaaattc
     9301 tactacaagg cgtgaaacaa aaacgactaa ttgggcaatc agtatcaacg atataaaact
     9361 tagatttcct ccacgaatac ccacatcaac taaagattga gttaaaaaag ggaaaatcag
     9421 ttggagaata ctaattacca gcatccctaa tattaattgt aatagctgac ttttgtaggg
     9481 gatgagataa tggaaaaaat atcgtaaact tctgctatgg ttatcttttt cttcttcacg
     9541 gtggaaaaat tcggggctag gttccaacag caatgctgca cccatctctt ttccattttt
     9601 ttttgtgcta taccaacatt ttttgaaatc cgattcacca tacgttatta atcccaatgc
     9661 tgggtctgaa actgatattc tccatctctc cctcttgtct ttgatgattt tatagacaac
     9721 tacaaagtgg ttttgtttcc aatgtaaaat acaaggtaat ggcacatctt ttgccaattg
     9781 ttgaaatgaa atcattacgc ctgaggtgcg aaaaccaata tattccgcag catcacttat
     9841 acccaacata gacactcctt cgcgggtgat gaatgaatgc tggcggagag tttcaagact
     9901 gtaatgttta ccataatatt ttgctattat tcgtagacag ttaggtccac agtccattga
     9961 atctaattgt ttataattag ggaaagggtg tttcatcttt ttaccttttg ttatatttat
    10021 ttctttggat aatacttgta taatatctgc gcaaaaaatc atatataaca agttcatgaa
    10081 ctctattatc agatagaaaa attcgatcaa tcatcatatg aatatagcta gtcaataaat
    10141 tagataataa cagggttcta ttatttagca gtttcttttt tatgttaata actattggtt
    10201 ttagcattat acttctttta aaaataggaa tctcacattt cttaaagtca gcttcattca
    10261 aatttcctgt taatactaat tcaataagtt ttttattctc tcggtatttt gtattgagtt
    10321 gtttagaatt taactcattg aatccaaact cagccctaaa agactcacta catttctcta
    10381 caaaatcttt ctttgaagcc aaatctaaag aaaagtctga taaaagacta tctaccattt
    10441 ctaatgaaat caaccatctg taattctcgt ttttggaccg atttacttgt ctcaaaatag
    10501 atataacaca gttgctatca aaacagaata gagattctgc ttcttgaatt aaatgagagc
    10561 catacctttc tatttctctg ttataagtat caagttgtat cttccaaata atccttttat
    10621 tgactagcga gttaaatttt ttataaaaca aactcataat gtaactgatt ttctccttat
    10681 ctattagcaa tctaaggcgt atatgaaaat caggatccgc atatcgaata aagaaccact
    10741 taaaaataca tttctctttg tccaaattgt ggacaaacct atagacttca tttgttaaaa
    10801 ttttatcggc ggttttctca cctgcatata ttttaaagta taaccactca ctaccaggaa
    10861 taaaggttct aattattgat gtcattgttt atagaagcta attatacatt cacttaaata
    10921 gggttgttct tcagacttaa ctagtgcatt ctgcttgtcg aaaaggaatt cttttagtct
    10981 aaatctattc cggcgtttta ttatggaata aaatgcttta acactataaa tattttcaaa
    11041 ctcaacatac aattcattat ctccatctgc taataatgct tcttgaggca aatcaatacc
    11101 ttttctccac tcatttatag aggaaagaat ttctttatcg ctctttcttg aaaaaatagc
    11161 ttttatatca tccgttttta tattccattg tgcaggtgat aaaataatat tattaaatct
    11221 cactcgtggg agaaatgaga acatttcgtc cagttttccc catgaaaaaa atataccacc
    11281 accttcttgt gcttgtatat cacacaagaa acgatatact ggcattagtt gaggattatg
    11341 aaaattatgt gcagtggtta atctaggtat aatttctttt ttgtttgaat taagcgttaa
    11401 tttgttatgt tttaaagaaa gagttacatc cgacaaatag attaacttat cactatttaa
    11461 atcggaggta gccatatata acaactcgta atctcttatg tgaggcctag ctaatatatt
    11521 accaattctt gattctggga gatggccaat ttctgccaat atcttctctg ggaataattc
    11581 cttttcttta ttaacaattt ctctgactga tctttccaga tctggctgga ggtgagcaaa
    11641 acggcccaat aaatttgctc cggaactccc attaaatgaa tttaaggcga ttaattgatt
    11701 attatcatca ttctttatga cttttaaaag agtatatatc gttgaaggta agtttacttc
    11761 ttccttcaac gactgattaa tatctttttc tgtaaagata atttcttttt tcttatctcc
    11821 cttagtattt acaattttgt ccaacataaa ggattggaat gcagtcaata caaaactttt
    11881 ttctccacta gtgttgggaa tatataaatc atctataatt ggggatatat tagaacctcc
    11941 cattttagag ggatatccta gtcctatgtc tggatctaaa acttctaaca aaggtatttc
    12001 tctctcttca tatctttcaa aaaaatcatg tttaaaatga tttagagttt cattattatc
    12061 tctacttatt gcatttagaa aaagcatgca gttttgcaaa tcaattataa tttgttcgtt
    12121 taatgtcgct tgatgagaca aaagaaaact atctacttga aataaatatt tctcctcaaa
    12181 agggacatcg atagatttaa taatcgaaat aatttcatta tatatttgat aatgatttga
    12241 aagggttgta tcaagttcaa ttaaaagatc tctgatttgt ttcaatgaat ataataaaga
    12301 tccctcttca ccacatttct caattaagtt aattaatctc tctaaaaaat catctcctat
    12361 aattgactga gataattcac caactaataa ctgtgaatca attagctcat tgatataatt
    12421 atatccatct tctattgata tgttgtgttc gcataattcg cataaaaagt taactaaatc
    12481 tttgattgta tacccgtttt tggccttaat taatatttct tccaaataag ttgaaccttc
    12541 aacttcagat atttgatatt ttctagttgc ccccgagtat aaagtttcta tgtaacgaat
    12601 attgctacct actttataga tgcttgaatt tggataatat ttgatctttt ttttaagttc
    12661 agtttctttt gttataaaat tatataaatt gcaaagatat tgcatatcta aacgagtctt
    12721 tctacttctc gcatctttta gtgaaatttg agtttctttt ccaaacgtcc ctaaaccgca
    12781 tcctgcaaat aaaccgaaag gagtacatct agtagacatt ctactgatgt atcttacgac
    12841 agaattaata atccgctctc tttctgaatc atttttaata ttattagcca gtaatttttt
    12901 aatttctgta tacaaaactg gagaagctaa aaaaatagcc tccagtattt tgttgtcaga
    12961 taatatttta aaaagtgcac cttcaccttc tagagcatcc ttaacagatt gaaaaggtaa
    13021 caagggagag cgaaaaatga atttttgaaa agctttatac atattcacga ttattacaaa
    13081 taataaaaat gtgttagact tatctgaggt taatataaac catttattct taagatgtta
    13141 aaacattcac taaaggaata caatgtaatc caagttgcac tatttagtta taataacaaa
    13201 atttcatccc acgccgtatc cacctcgtgg taggcagata taaaggaaac accaactcca
    13261 gctactcctt caaggattcc tcttataggc aattttaatc cttttttttg aaataaatat
    13321 cctcctattc cgtctgggtt acttcctaat tctattgttt tctgatacca atattctgac
    13381 gtatccgcaa atatcctatc atttgataaa ttatacactt tctgaaaaat ataagctatt
    13441 ccggcagagc catggcacaa acatgcatca aagacccaat tttgtatcgg atcgaatctc
    13501 tttgcagtat aagacaatat ttccaaagcc ttagctttca gatggctatc gcccatcatt
    13561 atagatgttt tatataaaat atagccaatc cctaaatctc catagcacca cgccaatctt
    13621 gtagaccttg ttggtgaatc agttgaatat gaaaaatatg tattaccttt attttcaggt
    13681 gtatgcatat tcgataataa aaactcaaca aatccgttta ttaaattatg tgatatggac
    13741 gtacatattt ttttctcgta tgcgattaat aaaattgcaa taatactcgg tatgccgtgt
    13801 gaaagtccca aattacaaga tgttttcttt tcattttcat agagaaaaaa atgattccct
    13861 ttggattgtt ttatttgatc aagtacttct aaatactgtt taatgtaatg aattggagga
    13921 ttttcttttc ttagaaaata cactaatgca cctagactgc cagaaatata atcataataa
    13981 ccaaatttca aatcctctaa agaatgatta aatataattt cgtcaacact tccaaaaaca
    14041 tcattactgc tgctatcaat taatcctttc cttttaacta catcaataaa ccacccaatc
    14101 ccactaagcc catgggaaaa agaatatcct attttattgt agctattact cattgttata
    14161 atcttatcta atttgctaaa gatataatca ggaatatatt gttctttcgt taaatcataa
    14221 taataaagta aaaacaaaag ttctccaact gtgcccccca ttaatccgca gttatcttgc
    14281 tcttggttat ttaaaagggc atctttgatt tttgttataa gagtaaatct taggttatca
    14341 aaatcattat agagtctatt catatttaat gttatatttt aaatagggag agaagctgtt
    14401 gaaaagccta caaacttctc cccctaaatt atttatcatt tgaaaccgca agtgaatttg
    14461 gaacgatcat aactacaatc tgctatagaa ttaaaatcat gatcacaata acttcactgc
    14521 aattcctgtt ttatcttaca aagataaaaa tgagataacg gtaaagaata gtatatttct
    14581 taaattgcca cataaagcat tctgaaaact ctattatata tgacattttt aactagtaaa
    14641 tatctattat caatatttgt tatcagcatt atatacattc cttgccacta agtttgaagt
    14701 atcagataat catacttgac aacgcaaggt agggcaatca ccagatgccg tccaagtagg
    14761 atccccacaa tgaccacaat catgagtaca atctgcttta ctgcaattcc aaatgcgtgt
    14821 gtgaccccat gcgcttagac atccatcaga acatccagcg gacattccac ctttcaaatt
    14881 tgcttgttca gttttaccta aagaagtaat aacgtctttc tttagtacca atttccttaa
    14941 ttttttcata attttaagtt gttaagttat tattacccta atattacgct agggactgca
    15001 tttcgtttca tgtataaatc tgatgactct aaagttgaat ttgttcagaa tgtcagtatt
    15061 aataagattc actagtgtag taatgaactg ctctttttaa gtgctaattt ctgtaacttc
    15121 tccaaaatct tgtttattaa ttaattattt gattttttac cgaagggtat cttttatttt
    15181 ttccttataa atacaaaaaa tgaaataatg ataaagaata gcacacagga tatgtttaag
    15241 tattcgcctt tcgaaaagtc tattatccca ctataaaaac catagtttaa tctccacact
    15301 gtaccatagg gtataagata gatataatct ttattttgag caataacccc aaagatcgtc
    15361 atgaaaccag caaacccgat aggtaaaaca aaactcttaa agatcaaact aagataatat
    15421 tgcataattg aaacagcaga aagtgctata aacaaatatg agaaataaaa agctgttagg
    15481 ttattaacat tataactgga gaattcatat ccaggtaata acttatccag agcaaaacca
    15541 gacagaagga aagcaagata acctatgagg aaagaaataa agttaatctc taaaaggaag
    15601 accattttgc tcgaataaat tgtcagcttg ctaattggtc ttgtaaaaag aagtctaaat
    15661 ccataattct tatattctac atcgcataaa gaataactca aaatggctgc aagaattgga
    15721 taaagcagag catagaagtc gaagatgtat ctacccaata cccataccca aggattataa
    15781 tcaaaagtta ttgttggatt attgacagca tcagcatgtt taaacaaaac atatatatca
    15841 atgcataaag tcatgaacaa aggaaataac aagaagagcc aaatggcaat attaaatctt
    15901 aatttatagt gttcactttt aagaatagta aagaacgata taggtttcat aagtcggttt
    15961 ttattagatg aaggaataca gactccaaat tttcttggta tgtatctgca aataaaattt
    16021 gaatgtggtt ttgttgcatt aattttttaa aactgtcaaa ggaaccatct tgctctattt
    16081 ctataataag cgttccatca gagatccttt ttgtgggaat caagtgttct ttacatatct
    16141 tcatgcatcg ttccggttgg tccgtatgta ttaaataaga ttgctttttc tgattgagta
    16201 gactattaat ttctccttga aacaataatc ttttattatt taatattccg atgtgtgtgc
    16261 atattttctc catttcagct aagatatgtc ctgaaatgaa aatagttatt cctttacttt
    16321 taagtttgag cattagctct ctcatttcaa aaacaccttg aggatctagt ccattgagtg
    16381 gttcgtcaag aatgagtaat ttaggattat gaaacattgc catcgcaatt cccaagcgtt
    16441 gtttcattcc tgtagaatat tttctaactt ttttgtcttt atctttagtc aaattcacaa
    16501 gctctagaac ctcttgaatg cgtttttgtc cacaatgata tagtatatcc aaatagttta
    16561 gattctcata ggcactcaaa tctgcataga agaatggatg ttcaatcaag catcctatat
    16621 tttgaaggat atgcaatctg ttggaatgaa attctttttt attgaaaaat accgtattta
    16681 ttttagtttg ctccaatcct aaaagtatct ttatcgttgt tgatttaccc tctccattct
    16741 tgcctaagta tccataaatg gaaccttctg gaatcttcaa gttaatgtct tctaatacag
    16801 aatgatttat gtagttaaaa gtgagatggt tagtttcaag tatattcata atcaacactt
    16861 tcttttaaaa ttattcgtat ttaaatgatt taatataatc ctgtagctct tctttagaac
    16921 tatttgatat tctatataat tcattggaag atatctgatg aaatattttt gatcggaaag
    16981 aactattttc ttttctcgga tgacataaat ggaataaagg agtatcaacc ctatatatat
    17041 tatatccaag gtttttgaat ctattatagc tgtcataatc ttcattcccc catccataat
    17101 gtctttcatt ttccattcct gcatcaatat atttattcct atttacaaat acggcacctc
    17161 catacattgg ctgattgtaa agaaaatcaa gtttattaag attcttatag agaaccttga
    17221 tatctttagt atttaaataa tatctccgca agatatctga tgtttgataa acaattccat
    17281 tataaggata tgcgatgtct gcctgacgtg aacgaagaat attgacggcc tccattatag
    17341 attttttatc aataatagtg tcagaatccc aaatagcaat aataggtgtg ttattttctc
    17401 gtgtgagcct attgtaatat acagtccgat gaaatatatc atccatatca tttacaaaag
    17461 tataggacac ttttcttggt aataatgatg ctaaaatact attattatga ttagcacctt
    17521 ctattatagc tatattcgtg tcaaaatatt tattgatatt aaatataaca atcaaaaggt
    17581 tttcaagtcg ttcaatagaa tccaatctta taacgaagac aaatgttgta tctttcaagt
    17641 ttattttcat accaactctt ctgctaaatt tgtaattaag attacccccg tgtatccaaa
    17701 caaacctaaa ttgatcttcg ataaatctga atcatttaac ttccaaatgg cagactcatt
    17761 tattttatca ataaattttt cgaagaacaa atttgtattt atttgttgtt ttattgcaga
    17821 aggcaaagta accatcagaa gagctatccc tgctagacca tgttcgaaaa acatattttt
    17881 atcatagaat tcatttatca aaacttcgat attaatctga gatgctaaaa aattacaata
    17941 atgagataat tttatatttt taatctgttg atttacacta ctaattcccc atattaactg
    18001 aagttttata gaatcaaggg gtggattctt tgaaattata aaaggagtaa tttcataaat
    18061 gatttttttt atttttatat tgtaaacgtt ttgctcatat actttaccca aagcatatag
    18121 gaaaaggggt aattgggtat aaatggaaaa tgtagtatca cttttctcta tgaaatgttc
    18181 acaatgactg tgtaataaat ttattatgta tatgctcaat tcattaaaaa aataatccaa
    18241 ttcgcctgat gtactttctt ttctgatata tatataaaat aagatctgaa ttaaagtttt
    18301 aggatcttta tcaaagtttc ggaaggatat ttgcttaaaa atctcatcat ctatatcaga
    18361 aagtacagta tttacatttc ctttaataat atcttttttc aataaaaaag atattgctaa
    18421 gccaatccca gctaatccgt tttctatatc aattgattta atggtgtgaa gttggcttat
    18481 tacttgttct aacagctttt cagctataac tttaaagttt ttattgcttt tacggtaatc
    18541 taacatataa aagtatatgc atagtcccat cttgcctcca aatagtccca aagagtgctc
    18601 tgaatcattt agggagttct ttaatctatt attaatacaa tttattagta gccgattcat
    18661 ggattgtttt ttcgatttat gataaattat aaaaacacaa gagctaaatt gcagatatgt
    18721 tatacttttt acaaaagtaa gaaagatatt tgaaaaaagc gatgttttac atagtttaac
    18781 actttgtaaa tgaagtacta agtgcgaaat aataagattc tctttttaaa aagaaaattc
    18841 aggtgtccta aaatttaatt tctttctaag ttttttattt attttccctt gagtcctatc
    18901 aatttctttg gtgtctatta ttttagatat tcaaccgttt tggaatatat tgtctaatga
    18961 gcatgatagt atgtctatga gttttttagg gagaaagaat attttcgtat ttaatgccga
    19021 ttccaactca tggaatctta taaactcagg tccgttgtca gctgttatgg attttacata
    19081 tttcttgatg tgtcccagtt cttcaatgac ggctttattt acgtcctctg cacacttact
    19141 attctgaaat ttcctgttga taaccatccc agtacttctt tctgctattg ccagtgctgc
    19201 caaattgttc tttccagaat gcgatccatc gcctagtccc tctacctttt cccatctgct
    19261 tcaggtgatc tttgggctat atttttcttc ttgttccgtt actctaacct ctttctctgc
    19321 agagccagaa gctttagctt taacttgaac ttgtaatagg tatggagctt ctccctccat
    19381 ctatcatgcc ttatcatctc ataaatcgtt tcatgcgaaa cataagaact tcccacaatc
    19441 cttatcatgg gggcgggtaa cattgttcat aatcttagat aggttgagtg gaataaccct
    19501 cataaaacac tcctggcaga ggagtttaag caatttttac tttagccgtt gaacgtcgta
    19561 atgacgaaag catcatcaat tacaaagacc atccgttggc acattgtgct gagccaaccg
    19621 ctaatcattt ctttcccttt ttgtatgtct tggatgcttc cgttgtggaa aagataattg
    19681 tctttaacaa tgtttgcaat ttgggaagta tgacgatgac ggagcgaggc ttcctatttc
    19741 tttcctctca cattcatctt ataaatggcg tgtagcatga tgtagtgggg gatggtgtta
    19801 tagcgtattt cactctttcc ttgaccgttc acttgataat ctacgctctt gagtttgtgg
    19861 aagaggtcga acgcttcgaa ttttacagca aatttacctt tcatgaagct ttgactaacg
    19921 tacgcattgc acaccaagtt attgatatta atctgttcat cggcataacc tttacgacaa
    19981 aacattttga gatccatacc cattttcaat cccgatttca tgctatacga accgatgaaa
    20041 ccatattcgt agtcgtaggt gttgagggtt atgaagttct cacgggcact attgacattt
    20101 cgccaagaga gttgtcccat caaactccag cttaagtttc ctttttgata cttcacctcc
    20161 agatattgtc gggtaatatg gttattcact ttgctcaata cactacgcgt ttgccccgca
    20221 actcccgcca agtctacatt gtgattgtag ttatattctg tttcagtgaa taaattgaag
    20281 tacttcatgc tatccaacgg aacattataa taaataccgc tatgtgccga ccagttaccg
    20341 tttacgttct cgggtttgta agtatataca cccgtttgtg ggttgtagat gaatccgttt
    20401 gccacagcat tgtgcgttcc ttgaatatcc aagttaatgg atggcaattt atatcggcta
    20461 ttatgattat cgctaaatct tattcccaat gaactctgta tgccattttt caagttcggg
    20521 tttcccaatg agatggctaa tggattagag tcgtcgcgac gatcaatcaa cgaatacata
    20581 tcaggagtag tggttgtcga attaccccac ataataaatt gatattcatt gcgaatcaat
    20641 tgacctgaaa agtttatttg tttgatccaa ttattttgtg aaacaagttt ggtgataggc
    20701 tcacttctat aatccaattg ctctttttta taacttaatg ggacaaatat accaaataca
    20761 aaggtttctt ttccttttct tttcatataa tgtacaccga tagttcccgt atgttgttta
    20821 ctcatgtaat agcctgtgta actattattg aggtctaacg aacgtaagag ggaatcccac
    20881 gtagagggta gacttccaat gctatgatct tcatttttcc actcttgtaa tcggtctaat
    20941 cgatatttat tgttgtttcg ataattgcca gcttgcctgt attcataccc agtgaagatg
    21001 ttaaagcctg aagggagaac aaatatgtac tgcggctcta atttatatga ataggtatat
    21061 gaaggtgatt cgtcatgtcg gttgcgataa tcttttcccc ctgtatcttg aagatagtct
    21121 aattgatatt tactgaaggt gtaattcttg attttttcgt atgtgctact ggcttgaatt
    21181 cctattctgt cacctgattt caagggcttt cccaagtatg tttctaatgt tgaactgagt
    21241 gtatgaccat tgccgagcga ttgagataat tgcctattta cgcttttata ggtggagagt
    21301 cgttgaaggg ggacagtaaa agcagagtcg aggatagctt ctgttgaccc taaactccta
    21361 gggcttgtct ggaaagtggc tgacttgtcc gtgctgaaat tatcaaattt gttataattc
    21421 aaccgcagaa aggccataag ctggtatgac ttattgacac gaaactgatc atttagttca
    21481 taaatcgcat tcttggcggt actgttgttt atgcgtcgtg tgaagttgtt gttagcggta
    21541 cctaagaaag attcagctgc cgcgtgcgtg acattatggg tgttgatcca tgaaacactt
    21601 gtcgatagac tgttactcac cgtgttcttc tcgttactgt tggcaaggtt gaggccgatc
    21661 gtcttcatgg ttacttgtcc ttttggcaac ttggtaggat tccaatcgcc tttttcacca
    21721 ggctttcggt cttcatttac gttgttgata ttggcgaacg tggaaacttg catgtgtggt
    21781 gtaaagtaca agctgaacaa cttgagggca tatctgctat tggttccacc cgcaatgtcg
    21841 gcattaccga tgaaattcct ttcgtattgt ttcttcagtt gaatatccat cacgtagtcc
    21901 tttttctcta cgtcaatgcc catagcttga ctcttttcgg tgcttttttc aaacactttc
    21961 aggtctttta cagtgtaatt gggtaggttt tcgatgagtt gtttgttgtt acccttgaag
    22021 aaatcttttc cgttaagtgt gaggtaatcg agtttacggc cattaatgaa tatctcgcca
    22081 ttgctgttca ttgttgctcc aggcaattgt cgtatgagca catcaagcat actaccttcg
    22141 ggaaggttga aggcatcggc attgaaaata atggtatcgc ctttgttaat cattttgatt
    22201 ttggtactct ttactactac ttcgcccaag gtatgttcta tctcttccat ccgttttcgt
    22261 ttcagggcaa ggtctttcaa gtcaatcatc gttgcacgag tcttgaagct aatctcttga
    22321 ctgtagtaag tggtttcgta tttgggattc tccaccttga tgatatattt gccttcggaa
    22381 accttgggtg tcataaagaa ataagattct gggtgaacgg cattcttgtt ccatgcctgt
    22441 gtggaacaag tatcaaccac cgtactatcc aaagtcatca atgttatctt gctatcgata
    22501 atggtaaggt ttgtaaaact gtctaccaca cgcccgtaca ttttcatgtc acgcgtcttt
    22561 ttagaggtag gtgaaggctg ttgcgcaaat gattgctgag gcaaagccag catcatgcat
    22621 aataatattc ccaaaagttg tttcattatc atataggtat tttctatgtc aatcgtgaat
    22681 agatagttac aaagttatca ataatatgct tataagacgc atttttttta aactttaaaa
    22741 atatttttta ttactttttt gttttttcaa tatcccttta tttctctatt tatcctctat
    22801 tctcgcttgc ttaatatgta tagtattatt gtatataatt ttgttgttca ataattattt
    22861 accatcctta aaacaaccaa tttatggaat cgaacaacaa tgattatgta ctggtcttgg
    22921 aagatcgaac agaagtagag agtgttaacg aaacaggaaa actttccgta gtttctagta
    22981 ttgacgacaa gggaaacctt aaaacaacag aggctgtcgc tgccaaccaa gtggcattct
    23041 tgaagttcaa tagcaaagac ggacttctga agaacttcat ggccaacttc ctcaaacagt
    23101 tcaataaccc gactcatttt ggactgtaca aggtcttggc ggacaatgtg gagcagggtg
    23161 tggacaacct gcgcaccctg ctgcaaagcc gtgaaaagcc cgaaagcaaa cagcaactgg
    23221 ctgagatggg agtgcccttt gaggattacc tgccccagca gaagaatgct actgccatcg
    23281 atgagtcgaa gattgattgg aagcaactcg ataatctcgg actttcccgt gagcgattgg
    23341 agcagaatgg agaattagaa aaaatgctca actggcagaa gagcaatctc atcacaattg
    23401 ctgttcctat cggcggcacc accatctaca ctgaagcacg tctagcgttt cgtacggacg
    23461 atagcggtaa tatcggtttg gctattcatc ctctgagaaa agagccacag cttgactttc
    23521 cctatatggg ctacaagttc tctcccgaag aaaaggaggc acttctcact acgtgtaatc
    23581 tgggcaagac catcgaggta acacccaaga acgccgaacc tttctctgca tacgtttcca
    23641 ttgactcgca aacgaatgaa atcatagccc tgcgtgccga ccgagtgaac atccccaagg
    23701 aaatcaaggg cgtaacgctc tctgacactc agtacaaaga ccttgtggaa ggcaaagccg
    23761 tgaaggtgga aggtatgact gccaagagtg gcaagtcttt caacgccacg cttcaggtca
    23821 atgccgagaa gaaaggcatt gagtttatct ttggagacaa caagagttta agagaacgac
    23881 aggaacacaa acaggctcag cagcaaggcg taccccataa gctctgcggg ctggaactat
    23941 cagaaaaaca gcgtgaagca ttggatagcg gtcgtacact atatctaaag aatatggtgg
    24001 acaaacaggg acaatcattc aacgcctatg ttcgcatgga caaggaacag aaccgcctac
    24061 gtttttacaa gtggaatcct gacaagaagc aggaaaccgg caaagaaaag gtggttgccg
    24121 tagccgaaga acacaaaacg caggtagccg tgaacaacca cggcaagacg aatgaagcca
    24181 ccaagaatgt gaaagagccc ttgaagacgg gacagacaca acctacttcc gagcagaagc
    24241 aaaagcagga cgagaacaaa caaaagaagt cccgtggacg taagatgtaa cccttatttc
    24301 tattatcgac tatgacaact tgtattatcg ccgagaagcc ctcggttgcc agagatattg
    24361 cccgcatcgt aggtgcaaat agtaagcagg acggatatat ggagtgcaac agttaccttg
    24421 ttacttgggc aatgggacac ctcatcgccc ttgccatgcc tgaagcctac ggtttttctg
    24481 cctataaagc tgaagacctg cccattcgtc ccaatccctt tcagttagtg gtacgacaag
    24541 tatgtaagaa caaggagtat atatccgatc cagcagcact aaaacagctc aaggtgatac
    24601 gctcctgctt tgacaaggca gatcgtatca ttgtcgccac cgatgcaggg cgagagggtg
    24661 agcttatctt ccgctatatc taccaacatc ttggttgtag aaagcctttc gaccgccttt
    24721 ggataagttc actcacagac aaggctattc gtgagggact ttctaatctc aagcctggaa
    24781 gccattacga caatctctat tattccgcca aggcaagaag cgaagccgat tggcttgtgg
    24841 gcatcaatgc aagccgtgca ttgtccattg cccgcaaggg aggctattca ttgggacggg
    24901 tacagacccc gacattggct atggtctgcc gtcggtacat agagaaccgt gatttttctt
    24961 ccgtaccatt ttggaaatta tccgttctca cagaaaaaga gggtttgtca ctgaaagcca
    25021 ttggcattac cgactatgag agtgaagcat cggcacagac tgccctcgct acgcttcgca
    25081 gtcagagccg gcttacagtg gaatcggtcg caagacaggt ggggcatacc gcaccaccac
    25141 tcttgtacga ccttactgcc ttgcagaagg aaaccaacag acgccacggc ttttcagcag
    25201 acaagaccct ctcaattgct cagagcctct atgagaagaa aatcacgacc tatccacgca
    25261 caggcagccg atacatcagc gaggacgtct ttgaggaagt acccgccctg ctccacaaga
    25321 taggtaagcc cctatccaat ccgcttaacc gccactcggt ggacaacgct aagataaccg
    25381 accaccacgc tattatcccc acgggagaaa caccttccgg cttattgacg gatgaagcaa
    25441 tcctatataa tatggtggta acccgtttta tcgaagcctt ttcgcctgac tccgaggaag
    25501 aacgtatgca ggtgctgttc acggacggca ccaacacctt tacttggaaa gcatgccgac
    25561 aaatctcctt gggctggaaa gccgtgcaga aagaagtcaa atcagatgac gaggaagagt
    25621 tacttgccac attgcccaat ttaacagagg gtgaactcct accacttctc aatgccgaga
    25681 ttaccgaaca caagaccaaa tcgaaaccgc tctataccga agccaccctg ctctccgcta
    25741 tggagaacgc aggcaaggaa gtggaggatg cagaaagcaa gaaggcaatg gcggaatgcg
    25801 gtattggcac acctgctaca agagccaata ccatcgaaac gctcatcctc cgtgattata
    25861 tccgcaggga caggaaatcc atcatcccga cagagaaagg cttggcggtc tatgagattg
    25921 tcaaggacaa gaagattgcc aatgcggaga tgacaggtag ctgggaactt gcccttgccg
    25981 ctattgaagc aggaaagatg ccatctgata agttctcaca aggcatcaac tcatacgtgg
    26041 gaactatttg cgaggaactc ctctcgcttt cttcagagca gaagtcctat cctgtctacc
    26101 gctgcccaaa atgcggacag aagagtgtcg gcatctatgc caaggtagcc aagtgcaggc
    26161 atgaaacctg tggctttcac gcatttcgtg aagtctgcgg catacatctc tccgaagata
    26221 acatccgtga cttgataggc tccggtcgta cgcctatcct taaagggctg accagcaagg
    26281 caggaaagaa gttcaatgcc cgacttgttc tgggtgaaga ctacactact tcctttgaat
    26341 ttgagaacaa aaaaggaaaa caaagaggga gataatcctg gcagaaacaa cgaggaacag
    26401 atataggttg gtagatacaa gtattacctg ccgacctttt tacctccact tttttattaa
    26461 aagaaaacac tatggcatac aataagaaag aagtccttca agccaacacg gaggctatcc
    26521 gtgtggtctt gcgcctggaa aaagaacgcc gtgaagccac cgaagctgag aaaagtatct
    26581 tacggaacta tcagggcttc ggtggcttga aatgtgtact caaccgcaca gataaccccg
    26641 atgatatacg ctattggagc aagtctgaac agaatctctt tgaaccaacc caacagctca
    26701 agcagatgat ttatcgtgaa gccgtagaag ccaacactgc caagcggtat tgggagagca
    26761 tcaaagcaag cgtactgacc tccttctata ccgataccca tatcgtttct gccatctcag
    26821 acgcacttgc ctccacaaac ctgcatataa gacgatgttt agacccttct atgggtatgg
    26881 gtgcctttgc cgagaccttt gcaaagcaag cgggtgttgt agatacaatg gaaaaggacc
    26941 tgttcactgc ccgcatctca caagccctac acccctatgg caaaggcaat atcttcgttc
    27001 gcaacgagcc ttttgaagct attggagagc tggaagagaa ggacaagtac gaccttatta
    27061 caagtaacat tccttttgga gatttcatgg tctatgaccg aaagtatagc aaaggcaagg
    27121 acactctcaa acgtgagtcc acacgtgcca tccacaatta cttcttcgtg aaaggtctgg
    27181 actgcatcaa ggaaggtggc ttgctggcat ttatcacctc acagggcgta ttggacagcc
    27241 ctcgcaatga agccatacgc cgttacctca tgcagaacag ccgccttatc tccgctctcc
    27301 gactgccatc gggtatgttt tcagacaatg ctggaacaga cgtgggcagt gacctcatcg
    27361 tcctacagaa gcagactggt aaagaaatca gcgagggcat tgagcagcag ttcgtagaaa
    27421 ctgtttctgt tcccaaggaa gaaggctctt ctgtcgtctt caagcataac tctctttttg
    27481 taggagattg gaaagacatt tctcatcgca ccattgccac agagcgcata atgggtacag
    27541 acccctatgg aagacctgca tgggagtatc ggttcacagg agggattgaa gaaatggcag
    27601 aaagtctccg aacacaactt actcttgaaa tgggacaacg tatcgaccgt aaactatatg
    27661 aaacaggtat accgatgaca gaggtagagc gagaggcaga agcggagaaa cagcttcgca
    27721 agttgggtat taccataatt cgggaagaag aaacagagaa gacaaagatt gaagacaagg
    27781 gtataaacga tgcctataac ctcatgcccg acagtatcag gaaacagttg ccaaaacttt
    27841 acagcacgga aaagggactc attggcgata agatagccta tgcacgctat ttcttcccta
    27901 tgggagcata cacagcctac cttctggaat atgaccctaa gagccgcatt ggcttcggtg
    27961 ccgtgacaat gggttacggc tgggagcttg gcaatatgtc cctcgatgag atggaaggcg
    28021 taaaagtaag aggactgggc attgaacgtg acctgtactt ctctcctaag aaattgcatg
    28081 agatagccga actggaagaa atagtcaggg gacaatatac caaagaagaa gtggtggcag
    28141 aggaaatcaa ggaagaagcg gtaacaaaga cagaagacac cgtaaaggag actgtgaacg
    28201 gtatttctga aatcgaaacg tccaacgagg aattagaaac tgaaacagga attaatgtcg
    28261 ggcaagtcat agaaccagac gattttacca ttaccaaggt acaggcaaaa gaaaatacca
    28321 tttccaatgg agagaccact ccattgcaac caccatcatc ggagtccgcc ccacaacaat
    28381 cagtatcagg acagccttct ataactatag aacctgcacc cgaaggcgta cccgccttga
    28441 cacttcatca tcaatacgag caggaaccac aggaaatccg tacggatatt gagtccccaa
    28501 gagagatgaa tggacagacg atattttttg atgacgatca tcatccggtg gtggacaaca
    28561 acatggaaga catcggacaa ccggagcagc tgtcactgtt tgccccggaa gaatacagcc
    28621 tttggacaag agaagtaagc cgtgtgaata atgaaatcaa ggataattca gaaacttcac
    28681 aggcgcaccg tcctgtaaca caaactgttt cccaaaagcc aacggagtcc aagatgcaaa
    28741 aggcagcgac cattcctcaa cggcgtaccc gtagtagcag gaaagcagct tcttcctctt
    28801 cacgtgagcc gtc
//
