LOCUS       NZ_CP021920            24408 bp    DNA     circular CON 31-MAR-2024
DEFINITION  Bacillus sonorensis strain SRCM101395 chromosome, complete genome.
ACCESSION   NZ_CP021920
VERSION     NZ_CP021920.1
KEYWORDS    RefSeq.
SOURCE      Bacillus sonorensis
  ORGANISM  Bacillus sonorensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4832293)
  AUTHORS   Cho,S.H.
  TITLE     Genome sequence of Bacillus sonorensis strain SRCM101395
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4832293)
  AUTHORS   Cho,S.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-2017) Bioinformatics Research Institute, Microbial
            Institiue for Fermentation Industry, 61-27 Minsokmaeul-gil,
            Sunchan-eup, Sunchang-gun 56048, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3.0
            Expected Final Version            :: yes
            Genome Coverage                   :: 181.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002202015.1-RS_2024_03_31
            Annotation Date                   :: 03/31/2024 02:45:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,075
            CDSs (total)                      :: 4,961
            Genes (coding)                    :: 4,743
            CDSs (with protein)               :: 4,743
            Genes (RNA)                       :: 114
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 218
            CDSs (without protein)            :: 218
            Pseudo Genes (ambiguous residues) :: 0 of 218
            Pseudo Genes (frameshifted)       :: 158 of 218
            Pseudo Genes (incomplete)         :: 77 of 218
            Pseudo Genes (internal stop)      :: 30 of 218
            Pseudo Genes (multiple problems)  :: 43 of 218
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:23:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4567832
            Orig. end                         :: 4592240
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP021920.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Microbial Institute for
            Fermentation Industry.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24408
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="15"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24408
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24408
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14408](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14408)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            325..888
                     /locus_tag="S101395_RS23875"
                     /old_locus_tag="S101395_04826"
     CDS             325..888
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326828.1"
                     /locus_tag="S101395_RS23875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04826"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_006639991.1"
                     /transl_table=11
                     /translation="MDFSKELKDLFLMQQAYATLFSVLNKIQIRGDEYFEELTSRQFMT
                     IVAILHLPEDETTINNIAKKLGTSKQNVNRLINSIEKKGYVLTEPSKRDRRAVNVKITD
                     SGKKVMEECGEKAIYFMADIFKEFSMEEIETLWNLLKKLYRYDGEKQDGFEETAPEFEL
                     EQNREELQARVLQEFSRRRKGDVQ"
     gene            885..1823
                     /locus_tag="S101395_RS23880"
                     /old_locus_tag="S101395_04827"
     CDS             885..1823
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014113992.1"
                     /locus_tag="S101395_RS23880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04827"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_006639990.1"
                     /transl_table=11
                     /translation="MTSVVEVENLRKNYNEKVAINGMSFEVKKGEILGLLGPNGAGKST
                     MINILATVLSPTSGNVKMFGRDLKKGAKHVKQGIGIVPQDLAIFEEISAEKNVRFFAGL
                     YNLKGNVLDKRVEEALKLVRLYERKDDKPKTFSGGMKRRLNIACGIAHRPELVIMDEPS
                     VGIDPQSRNHILESIKTLKNNGATIIYSTHYMEEAEAISDRIMIMNEGQIIAQGTKEDL
                     HQKVKNQTAYAFQLTQSERVNVGLIYQIEGVKSVQMTEDTFEITVDQSNDHVGDIIAAL
                     TKEGCQIINMASKKASLETVFLELTGRSLRD"
     gene            1835..2581
                     /locus_tag="S101395_RS23885"
                     /old_locus_tag="S101395_04828"
     CDS             1835..2581
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019258579.1"
                     /locus_tag="S101395_RS23885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04828"
                     /product="ABC transporter permease"
                     /protein_id="WP_006639989.1"
                     /transl_table=11
                     /translation="MKFLRMIKFDMLNIVRNPTLLFANTIFPFILIAMMGFVTKNNFGG
                     NTVSSYDYYGVNMTIFSAMLITMTAANTFMEEKVKKGNIRMVYAPVSRASIYLSKLLST
                     YIFGTVCYCSVLFLGQTLFHLNLGGRYLPYLMLLIDALVLFGCCFGTMFCCIFKNEERA
                     NGIMQIPVAFFVFFGGVFFGIHRLGEMINSISIFSPVYWVSECAFRLIYDHDFSIFLPV
                     TLCLLLASIVCTAVCHIAFKPEEYVC"
     gene            2575..3561
                     /locus_tag="S101395_RS23890"
                     /old_locus_tag="S101395_04829"
     CDS             2575..3561
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014113990.1"
                     /locus_tag="S101395_RS23890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04829"
                     /product="ABC transporter permease"
                     /protein_id="WP_006639988.1"
                     /transl_table=11
                     /translation="MLNVFRNRLDRMLTKKAVLIIAVVVVPLMIAAAIFFSNQTIVKDK
                     IAFITAGSQHIPSDPKADVLQVDTKPPLSSLVLGQYNFLVEEKGSGYKVTTLRNQTDQK
                     RIEQFFKTGHLPESYRGDDQIHNDRGIGTNILGFIVMLVFMQGVALTALYPEDRMLGAF
                     RRMLASPLSVGKYLFVQSIFTFLCLYIPSYLAIVITCQLFGAEIGYSFGMLAVLLSILT
                     AMATGFSICMTSVMKRNINLAASGISVVTCVLAGCFISFTGSNPILDAICSILPQNAFM
                     AFIHGVEVGRSVLEYKGQIVYLFIWTIMLWLIGFFVTKRRIGKGIYE"
     misc_feature    complement(3602..3615)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.69"
                     /tool="antismash"
     gene            3749..5488
                     /locus_tag="S101395_RS23895"
                     /old_locus_tag="S101395_04830"
     CDS             3749..5488
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178468.1"
                     /locus_tag="S101395_RS23895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04830"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_006639987.1"
                     /transl_table=11
                     /translation="MKTENKPASLKPFFSLILSTGIPRLALTIGLIASLVTTLVGLSIP
                     LLTRELVDGFSASSISMALAGILALVFIIQAVCDGFSTYFLSYAGQKVVASLRERMWFK
                     LLRLPVRYFDEKTSGETVSRVVNDTGIVKSLISEHFPQFVSGMITIIGAVVILLIMDWK
                     MTLLMLISVPITTVIMIPLGMKMHTISKTLQDETASFTGNVQQTLSEIRLMKASNAEHT
                     EKMKGLSGISKLFQYGLKEARIFALVSPFMHLVIMIVIVAIIGYGGIRVSEGTMSAGSL
                     IAFLLYLFQIIFPITSFTMFFTQLQKAKGATERIIEILHTEEEEGQEGLEMDISNLPIR
                     VENVSFSYGDDEPVLREVSFDVDPGQMIAFVGPSGGGKTTMFGLLEQFYEPDSGVINIG
                     ETPINKLSMKSWRSQIGYVSQDSPMMSGTIRENLCYGLDHADSIDDQKLWKVAEMAYAD
                     AFIKQFPEQLDTEVGERGVKLSGGQRQRIAIARAFLRDPKILMMDEATASLDSQSESIV
                     QQALSRLMKGRTTFVIAHRLSTIVNADQIMFIEKGKITGMGRHHELVASHALYREFAER
                     QLT"
     gene            complement(5606..6961)
                     /locus_tag="S101395_RS23900"
                     /old_locus_tag="S101395_04831"
     CDS             complement(5606..6961)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="S101395_RS23900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04831"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_006639986.1"
                     /transl_table=11
                     /translation="MGIKNTLSVYFVKWITKLGFAGLFILTLNIGFVTWGINHHFFLPA
                     NEPIKKAEKIQSKVESANYIDPSIIPPELDYTIFNKQTNKIVKSNMSSRNKQRSIEAYL
                     HPSKDRMSSFIRYDSRYESILIHYSLKIQFANIELRKVFPNPGVWISVFSILIYCVYLV
                     WNIRSFSRIIVQENQKLIQVARKIKERDLNIEFPRVRFNEYKDVMGAMESLSEALVKSI
                     QKEIEITNSKSEQISYLIHDIKIPLTVIKGNIELLEAMADEDEKESFRDVMNAIQQIEG
                     YIQEVIDINLDNKQDNTNMEEVSVTDFLCKLEAEVKSLGNNIIVEDWTHKEASLYIDVI
                     LLSRAINNIVLNGIERTPPHEKVQMIVKQDKDRIQFVIIDQGPGFSEEALQKGTELFYT
                     ENFGRTNNSHYGLGLTFTEKVIKQHNGRMKLRNNANNSGEVLVELPILLRKG"
     gene            complement(6952..7620)
                     /locus_tag="S101395_RS23905"
                     /old_locus_tag="S101395_04832"
     CDS             complement(6952..7620)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016937907.1"
                     /locus_tag="S101395_RS23905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04832"
                     /product="response regulator transcription factor"
                     /protein_id="WP_006639985.1"
                     /transl_table=11
                     /translation="MAKILAVDDDAAILRLVRKMLSIKKHEVTTLQSIKDITIEELNKY
                     NLILLDVMMPDEDGFKICEKIRSLIDIPIIFMTAKSDESSIIKGLSIGGDDYIVKPFSI
                     HEVNARIEAHLRREARPKKGTKSVFIDGDILIDLEAKKVMIKGEEVSFTKTQYKICELL
                     ALHKGKIFSKEDIYESVYSIESDSQISTVVEHIRVIRKKIAQFNLAPISTVWGVGYIWE
                     "
     misc_feature    complement(7614..7628)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 17.11"
                     /tool="antismash"
     gene            complement(7634..8401)
                     /locus_tag="S101395_RS23910"
                     /old_locus_tag="S101395_04833"
     CDS             complement(7634..8401)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03733.1"
                     /locus_tag="S101395_RS23910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04833"
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="WP_006639984.1"
                     /transl_table=11
                     /translation="MLQFYRCFLGECKKRKRSIFSLLHISIPLVLSGVLVMYFLFRNVP
                     VGAEASYIIFFELIGVGTPVIISIICGLVADSENEAGHFQNILGLIQSRTVSFTSQTTM
                     MIFSYFAAIFLTISIYTLALKHLIGVGEVNFTLYYLTGIIFAGTSIFQYFFYQFVGYNY
                     GIGMCSICGFGGVIIAALCLTTIGDKIWWLLPWAWANRFGEYVMDYLKMTGVKPVGNST
                     LVMGGYSFLIMTTGIILLSIVWINRWSGKKTND"
     gene            complement(8401..9159)
                     /locus_tag="S101395_RS23915"
                     /old_locus_tag="S101395_04834"
     CDS             complement(8401..9159)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03732.1"
                     /locus_tag="S101395_RS23915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04834"
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="WP_006639983.1"
                     /transl_table=11
                     /translation="MYLYLKSEMIKTKRTMIRKMLLVIPLICSILALGFNFLGGPEIVR
                     LSAETIINHWGILWLSVFVALSTGLLNNLEKKSTNFKTIIGLPIDLQKKEISRVLFTTG
                     LMGLGSLLLIIFIILTSLLVKTSPYLVSLSSCILAVILMFIASLWQIPFCLWLSRKTNL
                     FITLLLNSMLNLNLGSVFAPTGDWWFVPYSWHLRVQMPLTKLHSNGIPLPQNDELLSYS
                     VIPTALVLSLTFFFILTLITVRSFNKLEVK"
     gene            complement(9171..9875)
                     /locus_tag="S101395_RS23920"
                     /old_locus_tag="S101395_04835"
     CDS             complement(9171..9875)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002799.1"
                     /locus_tag="S101395_RS23920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04835"
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="WP_006639982.1"
                     /transl_table=11
                     /translation="MNNEYILQTRHLTKKYKKSTILNGVSINVRKNTVYGLLGPNGAGK
                     STTLKIISGLLKQTSGEVIFNGNQWTRKDLIYIGSLIENAPLYGNLTAIENLEVINTIL
                     GLPKERIQEVLQVVGLTNTGSKKVMNFSMGMKQRLGIALAILNRPKLLILDEPTNGLDP
                     IGIQELRELIASFPKQGMTVLLSSHLLSEVEHLADDIGIISNGILGYEGKYHSYDNLEN
                     LFTDVVRKHRAQ"
     gene            complement(10001..13102)
                     /locus_tag="S101395_RS23925"
                     /old_locus_tag="S101395_04836"
     CDS             complement(10001..13102)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="S101395_RS23925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04836"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_088273102.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.4e-113,
                     bitscore: 378.5, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.4e-11,
                     bitscore: 43.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4.7e-27, bitscore:
                     93.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNLEKGKTIMTSYFKPISKYMLRVPLHPNSLMERFYDIEKSIEA
                     IKNDTFLCEQLLVASENIYKTLVNKDFSTLSKKKKRNLIASLGNYINRAATRTTPFGLF
                     TGVGILDLKKTEASKPSKINIKKKSRIDAEWLFKLIKKIEVEHFYDLKFKMNTASYRKG
                     NRLHIPYNLDGKTVEINVNYSKPLMLIEKLCIKEHVSFKKMVRALQERYPKRDVDDLVA
                     YVKTLIEKEFIISEIRPPLCNTNLLTYTINELSKIPFLYEKYGKPLNEVDVLIGKYNDA
                     PIGQGTKNYLTIQEKLRRIHSFTNEKYLQVDTKLDVDGIYINERDIKNINKCITLLMKF
                     ASEIDDSKSYKNIFEEYRLKFIEKFGTYVEVPIADVLDEVNGIGALKSYSRPKNRFTQD
                     TPVTTEEHNLLKRYFMNKYLAAVENKHPIIITDEEINKLNMKVDEKRLPSSLELNFIIR
                     KNNNGENLLFLGPNIGSSAAGKTFGRFSYLSDGFSEVLDEVGRELKESEIDQVELCFVP
                     SNIRMANVTRINTPREYNLSMFTNSYNPNNELTLADILVGCDNEKFYLKNKRNGRLLNI
                     SGMNMLNLSSSSNIIRLLSDLNQDLEWSNTPWGAYYKEFIHIPEIRYENIILSNEKWSL
                     QNLRGQFERAPKIEEFMAEFQKFRRVYSVPDNVYFQFADNRILLDLSRKTNLNLLYKNL
                     FKFPSTFLEKAEAGNPAITLGEEYFSAEAVIPFVLKEEYRDNKSKKEFFNGSIYQQVSY
                     PPFKEWLFLKLYGPEDRQDELIEYMKYFISTQLDRSVYDKFFYMRYNDPKPHIRLRFRS
                     IEPNNLQIIYDKLSEYIIELQKMSIIYEVTINTYFPEINRYGGSVLIKDAENLFYHDSL
                     VVMEILKVMKQNSLSQEQVGVISLLHYLIDFGLSFENQLNYLQLNLKNSDIHKKEFKKE
                     KFDFINELDSYNNWEKAKKREDLKQIIDILEYRSKSINVYREHINRSNKHTSDFINIIG
                     SIIHLHFNRLFEIDRDFENKLYVYAYQTLYGQRVRRKMLHLQEL"
     aSDomain        complement(12383..12640)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_S101395_RS23925_Lanthipeptide_LanB_RR
                     E.1"
                     /evalue="8.10E-14"
                     /identifier="RREFam001.1"
                     /label="S101395_RS23925"
                     /locus_tag="S101395_RS23925"
                     /protein_end="240"
                     /protein_start="154"
                     /score="43.1"
                     /tool="antismash"
                     /translation="MNTASYRKGNRLHIPYNLDGKTVEINVNYSKPLMLIEKLCIKEHV
                     SFKKMVRALQERYPKRDVDDLVAYVKTLIEKEFIISEIRPP"
     gene            complement(13095..14408)
                     /locus_tag="S101395_RS23930"
                     /old_locus_tag="S101395_04837"
     CDS             complement(13095..14408)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="S101395_RS23930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04837"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_006639980.1"
                     /sec_met_domain="LANC_like (E-value: 2.3e-67, bitscore:
                     225.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDSIKTKTSIRDIASRIADISYVETESKRNEVNYRNAGEITQTL
                     SPMTLSHGYPSLCILFSNLGVTDNENCWIEYSNRYVQQIVNLINERGIFGASLFSGTAG
                     IAFSIRIASMRGLYYSKLQKSLDRFLYDQLDEILTNLNFKTNYEMFDYDVMEGLAGIAN
                     YLFIIENDPTSEKYLKKILTYFVSLSGYKEFSGEKIPNWHIINEFLFSDSEKETYKNGI
                     LNVGLSHGIPGPLIILSKAYKRGILVKGHFEAIKRIAYDLVKLKNQYDNNWGGMIDVKQ
                     YFNQECPLRLPTRSAWCYGTPGTAFSLLTAAEALNDRELSEIAKQAMKDLIGNEQKIFS
                     PSFCHGYAGISYLYKRFYEKTGVQEFDNESKRLKSKTQEFFDFINPFGYCDIEIKDNYK
                     LKLNSIGLLQGVVGILLSLLSFEENSPSIWNVAFLLDD"
     gene            complement(14475..16115)
                     /locus_tag="S101395_RS23935"
                     /old_locus_tag="S101395_04838"
     CDS             complement(14475..16115)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="S101395_RS23935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04838"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_208620336.1"
                     /transl_table=11
                     /translation="MNAIELKKSLLEEICIMLFIYLGFNLFSEWLNNISSYFNGKLRLL
                     LEYKINFLLIEKSSLLSMRDFENSDIYNKLTRLENEVGYRPFQTFQALLGIISACVTII
                     SSSIILLLWKPYLIIILFLLPFLSLFYYLKIAQENFKIHFERSNSEREAWYISYLMTHD
                     FSFKEIRMYGLRNYFLNRFWRLKQRFRDQDNGINKKKMIYGFIFNTIQDICMGVVVFIA
                     VISAFTGKLLIGNVATYIKSISMVQSNSQSLINSIYQLYESNLYMELLDEFLNLEIETV
                     DSNKIKINSIDEIEFRNVSFSYDGSKNSLENVSFRIKKGDLLAIIGVNGSGKSTILKLI
                     CGLYTNYSGEILINGIELKRIDHESYRKCISVLFQDYLKYEFTLGDNVSVGDTSNMNDP
                     EKINKTLEMANVTFLKDGNKSYQLNSQLGNWFDDGTQLSGGQWQKVAIARSYYREASLF
                     LLDEPSSALDAISEKHIFESFFKLATNEISIFITHKVEIAKHAGKILVINNGAVDGIGN
                     HSDLIRNCDVYRSLYEKDQIDSNSSMVSN"
     gene            complement(16775..16912)
                     /locus_tag="S101395_RS23945"
                     /old_locus_tag="S101395_04839"
     CDS             complement(16775..16912)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03731.1"
                     /locus_tag="S101395_RS23945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04839"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_006639978.1"
                     /sec_met_domain="TIGR03731 (E-value: 2.7e-09, bitscore:
                     35.1, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKFDDFDLNVKQASEKDVVKPEVGSRYLCTPGSCWKWVCFTTTA
                     "
     gene            17593..18027
                     /locus_tag="S101395_RS23950"
                     /old_locus_tag="S101395_04840"
     CDS             17593..18027
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024273.4"
                     /locus_tag="S101395_RS23950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04840"
                     /product="DinB family protein"
                     /protein_id="WP_309521058.1"
                     /transl_table=11
                     /translation="MNCNEGEATWNAFDVIGHLIEGEKNNWIPRIEMIITKGETETFPL
                     FDRFGQMEKNAEKTIEQLLSDFTDLRRENLGTLRRLIHSQTDFEQTGIHPEFGIVKLRE
                     QISTWVAHDLTHISQIARVMAKRYQEDVGPWKAYLRILNS"
     misc_feature    17605..17614
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.78"
                     /tool="antismash"
     misc_feature    17631..17645
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 16.71"
                     /tool="antismash"
     gene            complement(18250..18822)
                     /locus_tag="S101395_RS23955"
                     /old_locus_tag="S101395_04841"
     CDS             complement(18250..18822)
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018705593.1"
                     /locus_tag="S101395_RS23955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04841"
                     /product="GNAT family protein"
                     /protein_id="WP_006639976.1"
                     /transl_table=11
                     /translation="MLFESSRVKLRKVTIDDAELYHTWRNDIEVMRNTNPSLDIYTIDA
                     TRDFIEQVILGANTAKSYMMIEKENEKPIGITSLINIDDKNRNAECIIDIGEKDFWGKG
                     YGSEALILLLNYAFLEMNLHRVYLRVFSFNKKAIRLYEKLGFSHEGTSREALFREGVWH
                     DIVHMGQLQSEYFKQHENRRTARAVES"
     gene            complement(18829..19446)
                     /locus_tag="S101395_RS23960"
                     /old_locus_tag="S101395_04842"
     CDS             complement(18829..19446)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018705592.1"
                     /locus_tag="S101395_RS23960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04842"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_006639975.1"
                     /transl_table=11
                     /translation="MAPKVDEEYREEKKSTLLNAAKKVFIKNGYINTTMQDIMDEANVS
                     RGTLYNYFDNIDHIFIEVLKLDDQDNIDLFLDERPLWPAIKRWIEGWQIQIEEVDHSLL
                     VARAEFFISSKFVKNKGNFPYISERYERTASAIEKAIYKGVERGEFQLQLPPALIARYL
                     ISFINGLMLDTFQLGNANTKVKEQLSVLLFSLEQMMKPTKKE"
     gene            complement(19736..20917)
                     /locus_tag="S101395_RS23965"
                     /old_locus_tag="S101395_04843"
     CDS             complement(19736..20917)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388070.1"
                     /locus_tag="S101395_RS23965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04843"
                     /product="MFS transporter"
                     /protein_id="WP_006639974.1"
                     /transl_table=11
                     /translation="MSNTWKIYILAIISFLVGTSEYIISGILDNIAHTLGITIAAAGQL
                     ITIFSLVYAIFTPILMALTASIDRRKLMIYSLGLFVLGNILAFALPGYGWFIAARVIMA
                     LGAGMVVVTALTIAAKIAPEGKQGSAIATVVMGFTASLIIGVPLGRMTAEALGWKSVFG
                     GIALLGLIAMIIIFLTLPHTEGDKPVPLLQQLSLLRKRKVAMGLSVTFFWLGGYAIAYT
                     YLSPYLLNISGISGNLLSGVLLIFGIASLVGSKFGGYSTDRWGVPFTLVSGMTLHIITL
                     ILLSLVTHSYIGVLIILILWSFAAWSTGPTQQYHLATLEPELSGVLLGINQSMMQLAMA
                     AGAGVGGIFVENVSLASITWIGALGVAIAVVVFLLTSHSDTKLKAPNVKEVSQ"
     gene            complement(21045..21347)
                     /locus_tag="S101395_RS23970"
                     /old_locus_tag="S101395_04844"
     CDS             complement(21045..21347)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097670.1"
                     /locus_tag="S101395_RS23970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04844"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_006639973.1"
                     /transl_table=11
                     /translation="MEPIEIFKALSNESRLQILQWLKEPDRHFTPHEGIDMNTIGVCVS
                     QITDKLKMTQSTASQYLAILLRAGLIKAERIGKFTYYKRDEEAIKKLADFLKTEI"
     gene            complement(21590..21910)
                     /locus_tag="S101395_RS23975"
                     /old_locus_tag="S101395_04845"
     CDS             complement(21590..21910)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178452.1"
                     /locus_tag="S101395_RS23975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04845"
                     /product="hypothetical protein"
                     /protein_id="WP_006639972.1"
                     /transl_table=11
                     /translation="MNQETYIEISRTSQYINKMRGFSVLIDGVEMGKIKDGGRLRIDLQ
                     PGEHAIQVKIDWCTSQTLRFTLDEGKVLKFRCGSPIRGWKVFLVLFSTVARTENYLFIE
                     QE"
     misc_feature    complement(22257..22275)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.45"
                     /tool="antismash"
     gene            22313..22690
                     /locus_tag="S101395_RS23980"
                     /old_locus_tag="S101395_04846"
     CDS             22313..22690
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003178459.1"
                     /locus_tag="S101395_RS23980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04846"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_006639971.1"
                     /transl_table=11
                     /translation="MKIIISNNSKQPIYEQIYTQIKDHILANELKPGQPLPSMRQLAKD
                     MNVSLITSKRAYEELEKNGFIYSVVGKGSFVSVQNDEMMKEGKMKAIEEQLLAAIKNSK
                     DIGITLTELKELLTILYREEE"
     gene            22690..23571
                     /locus_tag="S101395_RS23985"
                     /old_locus_tag="S101395_04847"
     CDS             22690..23571
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011197485.1"
                     /locus_tag="S101395_RS23985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04847"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_006639970.1"
                     /transl_table=11
                     /translation="MDNVIELRHVHKSFECFHLKDFSMTVEKGFVTGFIGGNGAGKSTT
                     IKLIMNLLQPDSGTIKVFGLNYKEHEKEIKQRIGFVFDHNVFYEHLTFTEMKELIKRAY
                     VNWDDQVFNDYAKTFNLPLTKKIKTFSKGMMMKASLAIALSHHAELIIMDEPTSGLDPI
                     FRRELLDILHQLIQDGDKTIFFSTHITTDLDTIADYITFIHKGEHIFTKDFYEIEEEYA
                     IVKGGMELLDRETEQEFIAVRKSTHGFEALTANKSRTEKIFGDMALIEKPTLEDIMFYT
                     KKGAKEHVQLNT"
     gene            23552..24160
                     /locus_tag="S101395_RS23990"
                     /old_locus_tag="S101395_04848"
     CDS             23552..24160
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024741.4"
                     /locus_tag="S101395_RS23990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="S101395_04848"
                     /product="ABC-2 transporter permease"
                     /protein_id="WP_006639969.1"
                     /transl_table=11
                     /translation="MFNLIRKDIVLQKKTLAASFLVLCVYLMLDISPIWVGVVFSIVIS
                     MYAFSIDEKSSIHMLLNSLPYTRKEIVSSKYIVVVLFTCMVAAAIFIVNFIIHRELTIW
                     KDILLMVAIVMTAASFMLPFCYKFKSNYLLIASIVAFGLYMLTINFVVHNLNDQIREFI
                     HMLLTLQNTSLYLIVAISIITLYGCSWLLSIRIYRNKVF"
ORIGIN
        1 acatcgccaa tttctgcgga tcattcaacg gatccaatgg ttcggcagga cgcgggcgca
       61 attcaaacgg aagccattcc acctccacat cctttccgtc aatcgctttc tcaaactggt
      121 ctttcccaag aaaacagaat gggcagacat aatcagaata tacttttact tttattgtca
      181 tgtgtttttt cctctcttcc atccatttgt aactataata gttacaaatg gatcgcctgt
      241 caagaatcct ttcatatgat cttgacatgt cccggaaaat cactatacta aaaaagacaa
      301 catgttgtct aaaggagtgg aaaaatggat ttttcaaaag aactaaaaga tttgttcttg
      361 atgcagcaag cttacgctac gttgttctcg gttttaaaca aaattcaaat tcgcggtgat
      421 gaatattttg aagaattgac atctaggcaa tttatgacga ttgtcgctat ccttcacttg
      481 cccgaggatg aaacaacaat caataatatt gccaaaaagc tgggcacatc aaagcagaat
      541 gtgaacagac tcatcaacag catcgaaaaa aaaggatatg tgctcacaga accaagcaaa
      601 cgcgacagac gtgcggtcaa tgtaaaaatc actgattcag gaaaaaaggt catggaggaa
      661 tgcggggaaa aagcgattta ttttatggcc gatattttta aagaattttc gatggaagag
      721 atcgaaacgc tgtggaactt gttgaaaaag ctgtatcgct atgacgggga aaagcaggat
      781 ggttttgaag aaacagcgcc tgaatttgaa ctcgaacaaa accgggaaga gctacaagcc
      841 agggtattgc aggaattttc aagacgaaga aaaggggatg tccagtgacc agtgttgtcg
      901 aagttgaaaa tctacgcaaa aattataacg aaaaagttgc cataaacgga atgagctttg
      961 aagtaaaaaa gggagaaatt ctcggccttt taggcccgaa cggagctggc aaaagtacaa
     1021 tgatcaatat tttagccacc gttttatctc ctacaagcgg aaacgtaaaa atgttcgggc
     1081 gcgacttgaa aaaaggtgcc aagcacgtga agcaagggat tggaatcgtt cctcaagacc
     1141 ttgctatttt tgaggaaatc tctgccgaga aaaacgtacg gttctttgcc ggcctctaca
     1201 acctgaaagg aaacgttttg gacaagcggg tcgaggaagc attgaaatta gtacggctat
     1261 atgaacgaaa agacgataaa ccgaagacct tctcaggggg catgaaaaga aggctgaata
     1321 ttgcctgtgg aatcgcccac cgtccggagc tcgtcatcat ggatgaacct tctgtaggga
     1381 ttgaccccca gtcccgaaat cacattttgg aatcgataaa aacgctgaag aacaacggag
     1441 cgactattat ctattccacg cactatatgg aagaggccga agccatttca gaccgtatca
     1501 tgatcatgaa tgaaggtcaa atcatcgcgc aagggacaaa agaagattta caccaaaaag
     1561 taaaaaatca aacagcatat gccttccaat taacgcaatc ggaacgggta aacgttggtc
     1621 tgatttatca aattgaaggg gtaaaaagcg ttcagatgac tgaggatacc tttgaaatta
     1681 ccgttgacca atcaaatgac catgttggcg acatcatcgc agcgctgacg aaagaaggct
     1741 gccaaatcat aaacatggca agcaaaaaag cttctttaga aactgtcttc ctagagctca
     1801 caggaagatc cttgcgggac taggagtgat cgagatgaag tttttaagaa tgatcaagtt
     1861 tgacatgtta aatatcgtca gaaatccaac gctgcttttc gccaatacca tctttccttt
     1921 catcttgatt gcgatgatgg ggtttgtgac aaaaaacaat ttcggcggaa ataccgtcag
     1981 ctcatacgac tactacgggg tcaacatgac aattttttcc gccatgctga ttacgatgac
     2041 agctgcaaac acgtttatgg aagaaaaggt gaagaaggga aatatccgca tggtatatgc
     2101 tccggtttcc agagcttcaa tttatctatc gaaattgctc tccacgtata tcttcggaac
     2161 cgtttgctac tgcagtgtct tatttttagg ccaaacactt tttcatttga atctcggtgg
     2221 acggtatctc ccgtatttga tgttgttaat tgatgccctg gttttgtttg gctgctgttt
     2281 tggcacgatg ttttgctgca tattcaaaaa tgaagagcga gcaaacggca tcatgcaaat
     2341 ccccgtcgcc tttttcgtct tttttggagg tgtgtttttc ggaattcacc gacttggaga
     2401 aatgatcaat tcaatttcta tattttcgcc ggtgtattgg gtttctgaat gtgcattccg
     2461 gctcatctat gatcacgatt tcagcatctt cctgccggtg accttatgtc tgttgcttgc
     2521 ctcgatagtc tgtacagctg tttgccatat tgcgtttaaa ccggaggaat atgtatgttg
     2581 aatgtattta gaaacaggct ggaccggatg ttaacaaaaa aagcggtcct gatcattgca
     2641 gttgtggttg ttccgcttat gatcgcagcg gccatcttct tctccaacca aacaattgta
     2701 aaagataaga tcgcctttat aaccgctggc tcacaacata tcccaagcga cccgaaagca
     2761 gacgtcttac aagtggatac gaaacctcct ctttcctcac ttgtattagg acagtacaac
     2821 tttttggtcg aagaaaaagg aagcggctat aaggtcacca cgttgagaaa tcaaaccgat
     2881 caaaaaagaa ttgaacaatt tttcaaaaca ggacacctgc cggaaagcta ccggggagat
     2941 gatcaaatcc acaatgaccg ggggatcgga acgaatattt taggatttat tgtgatgctg
     3001 gtgttcatgc aaggtgtggc actgaccgct ctttacccgg aggatcgcat gctcggtgca
     3061 ttcaggcgaa tgcttgcatc gcctttaagc gtcggtaagt atttgttcgt gcagtcgatt
     3121 ttcacgtttt tatgtttgta tattccatcc tatctggcca ttgtcatcac ctgtcagctt
     3181 ttcggcgcag aaattggcta cagtttcgga atgctggctg tattgctctc aatcctgacg
     3241 gcaatggcaa cgggtttttc gatctgtatg acctctgtca tgaagcggaa tatcaattta
     3301 gcggcgagcg gaatcagtgt cgttacctgt gtgcttgccg gctgtttcat ttcgtttacg
     3361 ggcagcaacc ccattctgga cgccatctgt tcgattctgc cgcaaaatgc gttcatggcg
     3421 ttcattcatg gcgtagaagt cgggcggagc gtgctggaat ataaaggcca gattgtctat
     3481 ttgtttattt ggacgatcat gctttggctt attggatttt ttgtcacaaa acggagaata
     3541 gggaaaggaa tttatgaata gcgttctaaa gtcagtttac gctgacttta gaagcttatt
     3601 tttttattaa aaactttttt ccttggaact ttatgagata tatagcgtaa tattatgcgt
     3661 tatggtgtac gcttattttg gaagaagggg gcattccatt atcacacgat gtttagctca
     3721 taaaaactaa ataaaggagt ttagcaatat gaaaacagag aacaaacccg ccagcttaaa
     3781 accgttcttc tcattgattc tctcgacagg cattcctaga ctcgctctaa ccatcggctt
     3841 aatcgcaagc cttgtcacca cattggtcgg actatcaatt ccgctgctta cacgggaatt
     3901 ggtcgacggc ttttccgcca gttcgatcag catggctttg gcgggcatcc ttgcgctcgt
     3961 ttttatcatt caagcggtct gcgatggatt ttccacctat tttctttcct atgccggaca
     4021 aaaagtggtc gcttcattga gggagcggat gtggtttaaa ttgctgcgcc tgcccgtccg
     4081 gtattttgat gaaaagacga gcggcgaaac cgtcagccgt gtcgtcaatg ataccggcat
     4141 cgtcaaaagc ttgatttccg agcattttcc gcagtttgtt tcgggcatga tcacgattat
     4201 tggagccgtt gtcattttgc tgattatgga ttggaaaatg acactcctca tgctcatctc
     4261 tgttccgatt acgaccgtca tcatgatccc gctcggcatg aaaatgcaca caatctctaa
     4321 aacactacag gatgaaaccg cttcgtttac cgggaatgtc cagcaaacgt taagcgaaat
     4381 cagattaatg aaagcatcca acgcggagca tacagaaaaa atgaaagggt tatcaggcat
     4441 ttcgaagctc tttcaatacg gcctcaagga agcccgtata tttgcactcg tctccccgtt
     4501 tatgcacctt gtcattatga ttgtgatcgt cgccatcatc ggctacggcg gcatccgcgt
     4561 ctctgagggg acgatgtcgg caggctcgct gatcgccttt ttgctttatc tgtttcaaat
     4621 catcttcccg atcacatcgt tcacaatgtt tttcactcag ctgcaaaaag caaaaggggc
     4681 aacagagcga atcatcgaga ttttgcatac tgaagaggaa gagggccagg aagggcttga
     4741 gatggatatc tccaatctgc cgatacgtgt cgagaatgta tctttctctt acggcgatga
     4801 cgagcctgtc ttgcgggagg tatctttcga cgtcgatccc gggcagatga ttgcatttgt
     4861 cggtccgagc ggcggcggaa aaacgacgat gttcggcctc ttggaacaat tttacgaacc
     4921 ggactcaggg gtcattaata tcggggaaac accgatcaac aagctgtcga tgaagtcgtg
     4981 gcgcagccag atcggctacg tatctcaaga cagcccgatg atgtccggca ccatccgtga
     5041 gaacttgtgc tacggcttgg accacgctga cagcattgac gatcaaaaac tgtggaaagt
     5101 cgcggaaatg gcttatgcgg acgcatttat taaacaattt cctgagcagc ttgatacgga
     5161 agtcggcgaa cgcggtgtca agctgtccgg cggacagaga cagcggatcg ccatcgcccg
     5221 cgcctttctg cgcgacccga aaattttaat gatggacgaa gcgacagcca gcctcgacag
     5281 ccagtcggaa agcattgtcc agcaggccct ctcacgcctc atgaaaggac ggacaacctt
     5341 cgtcatcgcc caccggctct caacgatcgt aaatgccgat caaattatgt ttatcgaaaa
     5401 aggcaagatt accggaatgg gacggcatca tgagctggtt gcttcgcacg cgctgtatcg
     5461 ggagtttgcg gagcggcagt tgacatagtc tcagaaatat aaaaggtgtc ccgaatgagg
     5521 attcgggaca ctttaaaaat taaaatttca cacaaaagcg gtcaagtatt ctcttttagt
     5581 cattaaaatg aacttatctt ttgtattatc cctttctcaa tagaatcggt aattctacca
     5641 gcacctcccc agagttgttg gcattatttc taagcttcat tcttccatta tgctgcttga
     5701 ttaccttttc ggtaaacgtt aatcctaatc cataatggct gttattcgtc cgtccaaagt
     5761 tttcggtgta aaaaagttca gtgccttttt gtagagcttc ctccgaaaaa ccgggtcctt
     5821 gatcgatgat aacaaattga atacggtctt tatcctgctt gacgatcatt tgcacttttt
     5881 catgcggcgg cgttctttct attccgttta atacaatatt atttattgct cgactaagca
     5941 ggattacgtc tatataaagg ctagcctctt tatgtgtcca atcttcgaca atgatattat
     6001 tacccaagct tttaacttcg gcttccagct tgcacaagaa atcggttaca gatacttctt
     6061 ccatattcgt attgtcttgt ttgttgtcca ggttgatatc gataacttcc tgaatgtatc
     6121 cttcaatctg ctgtatagca ttcataacgt cgcggaaact ttccttctca tcctcatctg
     6181 ccatagcttc caaaagctct atattccctt ttataacggt caacggaatc tttatatcat
     6241 gtatcaaata actgatctgt tctgactttg aattggtaat ctcaatttcc ttctgaatgg
     6301 atttaacaag tgcttccgat aaactctcca ttgcgcccat tacatctttg tactcattaa
     6361 atcgaactcg cggaaattcg atatttaagt ctctttcttt tattttacgg gctacttgga
     6421 taagcttttg gttttcttgg acaataattc gagaaaaact tcttatattc caaactaaat
     6481 aaacacaata aattaagatt gaaaaaactg atatccatac gccaggattc ggaaatacct
     6541 ttcttaattc aatatttgca aactggattt tcaagctata atgaatcaaa atgctttcat
     6601 atcgactgtc atatcttata aaagagctca ttctatcctt actaggatgc agataagctt
     6661 ctattgatct ttgtttattt ctggaactca tattactctt tacaattttg tttgtttgct
     6721 tattaaaaat agtataatcc agttctggag gaatgatgct gggatcaata taattggcac
     6781 tttcaacttt actctgtatt ttttccgctt tttttatcgg ttcatttgcc ggaaggaaaa
     6841 aatgatgatt gattccccaa gtcacgaatc caatattcag ggtcaaaata aacaaacctg
     6901 caaaacctaa ttttgtaatc catttaacaa aataaaccga taacgtattc tttattccca
     6961 tatataccct acaccccaaa ccgtactgat aggggctaaa ttgaactggg caattttttt
     7021 ccttatcact ctgatatgtt caaccacggt tgaaatttga gaatcgcttt caattgaata
     7081 gacagattca taaatatctt ctttagaaaa gattttcccc ttgtgtaatg cgagcagttc
     7141 acaaattttg tattgagtct tagtaaagct tacttcctcc cctttgatca ttactttttt
     7201 tgcttctaaa tcaatcagga tgtcaccatc gataaataca cttttggtgc cctttttcgg
     7261 ccttgcttcc cgccttaaat gagcctcgat acgcgcattc acttcatgga tactgaacgg
     7321 ctttacaata taatcatctc ctccaattga taaaccttta attattgaag attcatcact
     7381 tttggcagtc ataaaaatga tcggtatatc aattaaagat ctaatcttct cacaaatttt
     7441 aaatccatct tcatctggca tcatgacatc taataaaatg agattatatt tatttaattc
     7501 ctctatcgtg atatctttaa tactttgcaa agttgtaacc tcatgttttt ttatactcaa
     7561 cattttcctg accagtctta gaattgcagc gtcatcatca accgccaaga ttttggccaa
     7621 attgaaccac cctttaatcg tttgtttttt ttccggacca cctatttatc caaacgatac
     7681 ttagaagaat tattcctgtt gtcataatta aaaaagaata acctcccatt acaagtgtag
     7741 aatttccaac cggttttaca cctgtcattt tcaaataatc cattacatat tcaccgaatc
     7801 ggtttgccca agcccaaggc aggagccacc agattttatc tcctattgtg gtcaagcaca
     7861 gagctgcgat aatcactcct ccaaacccac atatactgca cattcctatc ccataattat
     7921 aaccaacgaa ttgatagaag aaatattgaa agatggaagt tcctgcaaaa attatacctg
     7981 ttaaatagta gagagtaaag ttaacttcac ctactccgat caggtgcttc agagctaggg
     8041 tatagattga tatcgttaaa aatatcgcag caaaataaga gaatatcatc attgttgttt
     8101 gacttgtgaa tgaaacggtt ctgctctgaa ttaatccaag tatattttga aaatggcctg
     8161 cctcgttttc agaatcggcc accagcccac aaataatcga aatgatgacc ggtgtaccta
     8221 ctccaattaa ttcgaaaaaa atgatatagc tcgcttccgc acctacgggt acattcctaa
     8281 ataagaagta catcaccaaa acaccagata aaacgagcgg aatgcttatg tgtaataatg
     8341 aaaatatact tcgctttctt tttttacatt cgccaagaaa acatctataa aattgcagca
     8401 ttatttcacc tcaagtttat taaaagacct aacagtaatc aatgtcagta tgaaaaaaaa
     8461 tgtaaggctt aaaacaagag cagtcggaat aactgaatag ctcagaagtt catcattttg
     8521 cggcaaaggg attccattag agtgtagctt cgttaaaggc atttgcactc ttaaatgcca
     8581 gctgtatgga acaaaccacc aatctcccgt aggagcaaaa actgaaccta aatttaaatt
     8641 aagcatgcta ttcaacagta aggtgataaa aagattcgtt tttctagaaa gccacaagca
     8701 aaacgggatc tgccatagtg aagctataaa cattaagata accgctaaaa tacaagaaga
     8761 aagtgaaacc aaatatggac tcgtcttaac cagcaaactc gttaggatta taaaaattat
     8821 taacagaaga gaccctagcc ccattaatcc agttgtaaat aaaactctgc ttatttcctt
     8881 tttttgaaga tctattggta agcctataat cgttttaaaa ttcgtcgatt ttttttcaag
     8941 attatttaaa agcccagtgg aaagggctac gaacacggat agccataata ttccccaatg
     9001 attaatgatc gtttctgcac tcagccttac tatctccggg ccgcctagaa aattaaaacc
     9061 tagtgcaaga atggagcata ttaggggtat caccaacaac atttttctaa tcattgttct
     9121 ttttgttttt atcatttctg attttaaata taaatacatt cggtaacctc ctattgggct
     9181 ctatgctttc gtacaacatc tgtaaataga ttttctaagt tatcatatga atgatattta
     9241 ccttcataac cgagtattcc attgctgata atgccgatat catcagctaa atgttcaact
     9301 tccgataaca agtggctgga taaaagaacg gtcattccct gcttcggaaa tgaagcgatc
     9361 aattctctta attcttgaat cccaatagga tccaatccat tagtaggctc atctaaaatt
     9421 aatagcttgg gacgattcaa aatggcaagg gcaatgccaa gtcgttgttt cattcccata
     9481 gaaaaattca tcactttttt acttcccgta tttgttaacc caacaacttg aagaacctcc
     9541 tgaattcgct cttttggcag gccgagaatc gtatttatca cctcaagatt ttctatagca
     9601 gttaaattcc cataaagcgg agcattttca attaaagatc cgatataaat caaatctttc
     9661 cttgtccact gatttccatt gaaaattacc tctcctgatg tttgtttgag caaaccggat
     9721 attattttta gcgtcgttga cttacctgcc ccgttgggac ccaaaaggcc gtaaacagtg
     9781 ttctttctta cattaattga tacaccgttt aaaatggtcg attttttgta ttttttggtt
     9841 aagtgcctcg tttgcaagat atactcatta ttcatcttca aataactcct tttcgtcttt
     9901 ataaatggag tttagcaata aaaaatcaag actccatcaa tatcgaaaaa aacagatgat
     9961 tgatcagtta atctgttcaa ccatctgttt aagatgtttt ttaaagttcc tgtaaatgaa
    10021 gcatctttct tcgaactctc tggccatata atgtttggta tgcgtaaaca tatagtttat
    10081 tttcgaaatc gcggtcaatc tcaaacaacc tattaaaatg caagtgaatg atgctcccta
    10141 taatgttaat gaaatcactc gtatgtttat tgcttctgtt aatatgttct ctatagacgt
    10201 taatactttt gcttctatat tctaggatat caataatttg ttttaggtct tctctttttt
    10261 tagccttttc ccaattgtta taagaatcta gttcattgat gaaatcaaac ttttcttttt
    10321 tgaattcctt tttatgaatg tcactgtttt ttaagtttag ctgcaagtaa tttaattgat
    10381 tttcaaaaga taatccaaag tcaatcaagt agtgaagtaa ggagatcact ccaacttgtt
    10441 cttggctcag actattttgt ttcatgactt taagaatttc catcacaact aagctatcat
    10501 ggtagaataa attttcagca tcctttatca gcaccgaccc accatacctg ttgatttcag
    10561 ggaaataagt attgatggtt acttcataaa tgatgctcat tttttgtaat tcaattatgt
    10621 actcactcag cttgtcgtaa ataatctgaa gattgtttgg ttctattgaa cgaaacctca
    10681 atcttatatg aggttttggg tcattgtatc gcatataaaa aaacttatca taaacactcc
    10741 tatccagttg tgttgaaatg aagtatttca tgtattctat taattcatct tggcggtctt
    10801 cagggccata gagttttaaa aacagccatt ctttaaaagg aggatagcta acctgctgat
    10861 atatacttcc attaaagaat tctttcttac tcttattgtc tctgtattcc tcttttagaa
    10921 caaaaggaat taccgcctct gctgagaaat attcctcacc taaggtaata gcggggtttc
    10981 cagcctctgc tttctctaaa aaagtacttg gaaacttgaa taaattctta tacaacaagt
    11041 tgaggttagt ttttcttgat aaatccaata aaattcgatt atcagcaaat tgaaaataaa
    11101 cattatccgg gactgaataa actcttctga acttttggaa ttccgccata aattcttcaa
    11161 tttttggggc tctttcaaac tgccctcgca gattttgtaa actccatttc tcatttgaga
    11221 gaataatatt ttcatatcga atttctggta tatgaataaa ttctttataa tatgcacccc
    11281 atggagtatt actccattct aaatcctgat ttaagtcgct caataatcga atgatattgc
    11341 ttgaagagct cagatttagc atattcattc ctgatatatt cagcaatctt ccattccgtt
    11401 tatttttcaa ataaaacttt tcattgtcac atccaacaag aatatcagct aatgttaatt
    11461 cattgttcgg attatatgaa ttagtaaaca ttgaaaggtt atactctctt ggtgtattga
    11521 tacgggtaac attcgccatt ctaatgtttg atggaacaaa acacagctcc acttgatcga
    11581 tttcactttc ttttaactct ctgcctactt cgtccaacac ttcagaaaat ccatcgctca
    11641 aataactaaa tcttccaaat gttttccctg cagcagatga acctatattg ggtcccaaaa
    11701 aaagaagatt ttctccgtta ttattttttc ttatgataaa atttaattcg agagaactcg
    11761 gtaacctttt ctcgtctacc ttcatattta acttgttaat ttcttcatct gttatgataa
    11821 taggatgctt attttcaaca gcagctaaat acttattcat aaaatatctt ttcaaaaggt
    11881 tatgttcttc agttgttacc ggagtatctt gagtaaatct atttttaggc ctactataag
    11941 attttaaagc accaattcca ttaacttcat ctaaaacatc cgctattggt acttcaacgt
    12001 aagttccaaa cttctcaata aactttaagc gatattcttc aaaaatattt ttatagcttt
    12061 tagagtcgtc aatttcagaa gcaaatttca ttaataatgt aatacattta ttgatattct
    12121 tgatatctct ctcatttata taaattccat caacatctaa ttttgtatct acttgtaaat
    12181 atttttcatt tgtaaaagaa tggattcgcc ttaatttttc ttggattgtt aaataatttt
    12241 tagttccctg gccgatagga gcatcattat actttccaat cagcacatcc acttcattga
    12301 gtggtttacc atatttctcg tataaaaagg gtatttttga caattcatta attgtgtaag
    12361 ttagaagatt cgtattacaa aggggaggtc ttatttcaga aataataaat tctttttcaa
    12421 tcaaggtttt tacataggct acaagatcgt caacatccct tttcggatat ctttcttgta
    12481 atgcccgaac catttttttg aaacttacat gttcttttat acatagcttc tcaataagca
    12541 ttaagggctt actgtaatta acattgattt ctactgtctt tccatccaag ttataaggaa
    12601 tatgtaggcg attaccttta cgataagatg ctgtgttcat tttaaacttt aagtcataaa
    12661 aatgctctac ttctatcttt ttgataagtt taaataacca ttctgcatca atacgacttt
    12721 tctttttaat attgattttt gaaggcttgg acgcctcagt cttctttaga tcgagtattc
    12781 caactcctgt aaataaacca aaaggagtgg ttctagtcgc agctctatta atatagtttc
    12841 ccagggaagc aatcaggttt ctcttctttt tcttagataa tgtagagaaa tctttattta
    12901 ctaacgtttt ataaatattt tcgcttgcta ccaaaagctg ttcgcataaa aatgtatcgt
    12961 tctttatcgc ctctatactt ttttcgatgt cataaaatct ttccattaat gagtttggat
    13021 gtaacggtac tctaagcata tatttactta taggtttaaa ataacttgtc ataatagtct
    13081 ttcctttctc caaattagtc atctaataaa aaggcaacat tccatatcga aggactgttc
    13141 tcttcaaaag atagaaggga tagcaatatt cccaccacac cttgtaaaag ccctattgaa
    13201 ttaagtttca atttatagtt atccttaatt tcaatatcgc aataaccgaa gggatttata
    13261 aaatcaaaaa attcttgggt ctttgatttt aagcgctttg attcattatc aaactcctgc
    13321 acacccgttt tttcataaaa tcttttataa agatacgata taccagcata accatgacaa
    13381 aaggaaggcg aaaagatttt ctgttcattt ccgattagat ccttcatggc ttgttttgca
    13441 atctcggaaa gttccctatc atttaatgct tcagcggcag tcaataacga aaaagctgtt
    13501 ccaggtgttc catagcacca agctgaacgt gtcggtagac gaagtggaca ttcttggtta
    13561 aaatattgtt ttacgtctat catccccccc caattattgt catactgatt tttgagtttt
    13621 actaaatcat aggctattct ttttatagct tcgaaatgcc cttttacaag aatccctctt
    13681 ttataagcct tacttaaaat aattaaaggg ccaggaattc catgtgacaa acctacattc
    13741 aatattccgt tcttataggt ttctttttca ctatctgaaa ataaaaactc atttattatg
    13801 tgccaattgg gtattttttc acctgaaaat tccttataac cagataaaga aacaaaatag
    13861 gtcaagattt tttttaaata cttttcactt gtcggatcat tttctatgat gaaaagataa
    13921 tttgcgattc ctgctaatcc ttccatgaca tcatagtcaa acatctcata gttcgtctta
    13981 aagtttaaat tggttagtat ttcatctaat tggtcgtaca aaaaacgatc taaagacttt
    14041 tgtaatttag aatagtaaag cccccgcata ctagctattc ttatcgaaaa tgcaattccc
    14101 gcagtccctg aaaataatga agctccaaat attcctctct catttattaa attaacaatc
    14161 tgctggacat acctattgga atactctatc cagcaattct cattatcagt aactcccaaa
    14221 ttactaaaca atatgcataa agaaggataa ccatgactaa gagtcattgg agaaagtgtt
    14281 tgtgtaatct ctcctgcatt acgataattt acttcatttc ttttcgactc cgtttctacg
    14341 tacgatatgt cggcaattcg tgaagcaata tcccgaatac tagttttggt ttttatgcta
    14401 tccaacatat tgatctaacc tccctaaata aagcctttaa aaaacagcct tcttaaaact
    14461 gaagcttaca ctcattaatt actaaccata gaagagttgc tatcaatttg atctttttca
    14521 tataaactgc gatacacatc acagttcctg atgaggtccg aatgatttcc aatcccgtcg
    14581 actgcaccat tattaatcac caaaattttc cctgcatgtt ttgcaatttc taccttatga
    14641 gtgataaaga tgctaatttc attagtagcc aatttaaaga aactttcgaa tatatgtttc
    14701 tcggaaattg catctagggc tgaacttggt tcatctaaca aaaataaaga tgcttcccta
    14761 tagtaggatc ttgcaattgc taccttctgc cattgacctc ctgataattg tgttccatca
    14821 tcaaaccaat tgcccagttg agagtttaat tgatatgatt tattcccatc ctttaaaaaa
    14881 gtgacatttg ccatttccaa tgttttattt attttttccg gatcattcat atttgaagta
    14941 tcccccacag aaacattgtc tccaagtgta aattcatact ttaaataatc ttgaaagagg
    15001 acagatatac attttctata agattcatgg tcaattcttt taagctctat accattaatt
    15061 aaaatttcac cactataatt agtgtataat ccgcagatta atttgagtat ggtacttttt
    15121 cctgatccat tgacaccgat aatcgcaagt aaatctccct ttttgatacg aaaagataca
    15181 ttctctaagg aatttttact tccatcataa ctgaatgaaa catttctaaa ttcaatctca
    15241 tcaatagaat ttattttaat tttattagaa tctactgttt ctatttcaag atttaaaaac
    15301 tcatctagta gttccatgta taagttactc tcatacagct gataaatgct atttattaat
    15361 gattgactat tagattgaac catactaatc gatttaatat aagttgctac attacctatt
    15421 aataattttc ctgtaaatgc actaattaca gcaatgaaaa caacaacacc catgcaaata
    15481 tcttgaatcg tattaaaaat aaatccatat atcattttct ttttattaat accattatct
    15541 tggtctctaa agcgttgttt aagcctccaa aaccggttta aaaaatagtt tctcaaacca
    15601 tacattctta tttctttaaa agaaaaatcg tgcgtcatca aatagctgat gtaccaggct
    15661 tctctttctg aattacttct ttcaaagtga atcttaaagt tctcttgtgc aatttttaag
    15721 taataaaaca aagataaaaa cgggagtaaa aagaggatta ttattaggta tggtttccat
    15781 aatagcaaaa taatcgatga agatatgata gttacacatg ctgaaataat tcccaacaag
    15841 gcctgaaaag tttgaaaggg cctatatcca acttcatttt ccaggcgtgt aagtttatta
    15901 tatatatctg aattctcaaa atccctcatt gagagcaagc tacttttttc gataagcaga
    15961 aagtttattt tatattcaag tagaagccgt aacttaccat taaaataaga cgatatatta
    16021 ttcaaccact cagaaaacaa attaaatccc aaatagataa ataacataat acatatttct
    16081 tcaagtaagc tcttttttaa ctcaattgca ttcaatagct gttgaaacaa taagacagat
    16141 acgactgaag tcaaagaggt tccaattgta aggattacta caaaataaaa atttctacca
    16201 gttatattaa aaatcatctt aatcgtcttg cacaaaagcg ttagattctt cttaatactt
    16261 tgcattatta tcattccgtt ttattttttt tgttagcaat ttattataca aattttaaga
    16321 ctcatcattt ttctgtatgc agttcctttc atcccaaaat tatgtataga ttaaaaggac
    16381 tctagcactt aacctattat ttcttaggct agcagttaag cgctaaagcc ctaagacgaa
    16441 caattcagct tttaattaga acaatatatt acgcagttgt tgtgaagcaa acccacttcc
    16501 aacaagatcc tggggtacat aaatatctac ttccgacttc cggtttgact acatcttttt
    16561 cacttgcttg ttttacgttt aaatcaaaat catcaaattt tggcaatttc ggtctctccc
    16621 tttctaaatt tttcgaatct ctattaggta atttgcaaaa cctttgtctc atattcatcc
    16681 aatggtttaa ttaatgatgt agatctaaag agtgtctcaa aaactatgta ctccctccta
    16741 tatcgttgat tgaaaattat ctcactttaa ctctttaagc agtcgttgtg aagcaaaccc
    16801 atttccaaca agatcctggg gtgcataaat atctgcttcc aacctctggc ttaaccacat
    16861 ctttttcact tgcttgtttc acatttaagt cgaaatcatc aaactttggc attatcagtc
    16921 acctcctgtt aagaaccata ttttcagaag tacataagct caattaaacc ttttgaaccg
    16981 gattttctat atgatattgg ttttgcaatt ttgataatat taaaaaaata tcaagatttt
    17041 atcaagattt tatatttttt tgatattttg cccatttaat ggtttatttc ccataccagg
    17101 tatctaatat tttatgctca tatcaaaaac accctttttc cttatttcga tcaaaagcaa
    17161 aagggcaatg aggttttcgg atacaacttt attactctca gattatttca tactagcgag
    17221 aatttgctcc acagtgatgg taaagtgtta ctagtatgca ggttaatctc tgctgtcatt
    17281 ctttgacgtt accgaaggta tagttttaat tttcaaaggc aatgatcaat atgctgtctt
    17341 atgttgctgt gaattgaatc catcaaagtt ttgagttttt attttaagga atttgtaaat
    17401 tcatcatctc ttctatacat aaagcatcag ccgtaactaa accaatgaat caaaacaaaa
    17461 tgtaatatca cattgaataa ttccccactt catcatctgg atacacaagt atgaatcatt
    17521 tttaatatag aactcttgga acgcacgcca caaacgctga gtcatttgct gaccggatga
    17581 tcaggctcat ggatcaattg caatgaaggc gaagcaacgt ggaacgcctt tgatgtcatc
    17641 ggtcacctga tcgaagggga aaagaataat tggatcccgc ggattgaaat gatcatcaca
    17701 aagggagaaa cggaaacatt tcctttgttt gaccgttttg gccagatgga gaaaaacgct
    17761 gagaaaacca ttgagcagct gcttagcgac tttacggatc ttcgccggga aaacctgggg
    17821 acattgcgac ggctgattca ttcacagact gatttcgaac aaacgggcat acaccctgag
    17881 tttggaatcg tcaaacttag agaacagatc tcaacatggg ttgcacacga tcttactcac
    17941 atctcccaaa ttgcaagagt gatggcgaag cggtatcaag aggatgtcgg gccttggaag
    18001 gcttatttgc ggattttgaa cagttaacat tgttattcta gaacctgatc aagcgctcct
    18061 ttgaagacgg cccttcagac accgtttgtc atcgaaccaa ttcttgagcc gcggccttct
    18121 ttaatgcact ttagaagttc ttctggacat taaaaaagcc ccccctttgg ttaatcccgc
    18181 caaagggggg cttctcattt tggtttcaat tagcctttaa gatgactgaa ctttgctttc
    18241 gatttggcct caagactcaa ctgcccgtgc tgtccttctg ttttcatgtt gtttaaaata
    18301 ttcactttgc aactgaccca tatgcacaat gtcatgccat acaccttccc tgaacagggc
    18361 ctcccgactg gttccctcat ggctaaatcc taatttctca tacaaacgaa tcgctttttt
    18421 attgaaggaa aacactctaa gataaacccg gtgcagattc atttctaaaa acgcatagtt
    18481 caatagcaat atcaatgctt cgcttccgta gcctttgccc caaaaatcct tctctccaat
    18541 gtcgataata cattcagcat ttctgttctt atcatcaata ttgattaatg atgtaatgcc
    18601 aatcggtttt tcattttcct tctcaatcat catataactt ttggccgtat tggcgcccag
    18661 gatcacttgt tcaataaagt ctcttgttgc gtcaattgta taaatatcta aagaagggtt
    18721 cgtatttcgc atcacttcga tatcatttct ccatgtatgg taaagctctg catcatctat
    18781 cgtaactttt ctcagcttca ccctggaaga ctcgaataac atgactgttc actccttttt
    18841 tgtcggtttc atcatttgtt caagagaaaa aagcaataca gacaattgct ccttaacttt
    18901 tgtgtttgca ttccccagtt gaaaggtatc cagcattaaa ccattaatga acgaaatgag
    18961 ataccgcgcg ataagtgcag ggggcagctg gagttgaaat tcacctcgtt ccaccccttt
    19021 ataaattgct ttttcaatag cactggcagt tcgctcgtag cgttcagaaa tataagggaa
    19081 attcccttta ttttttacaa actttgagga aatgaaaaat tcagctctcg caaccaatag
    19141 agaatgatcc acttcttcaa tttgaatctg ccacccttct atccagcgtt tgatggctgg
    19201 ccacaacggt ctctcatcta aaaatagatc gatattatcc tgatcatcta atttaagaac
    19261 ttcgataaaa atatgatcaa tattatcaaa gtaattataa agagttcccc tggaaacatt
    19321 ggcttcatcc ataatatcct gcatcgtggt gttaatatat ccgtttttga taaacacttt
    19381 cttagccgcg tttaatagtg tgcttttctt ttcctcccta tattcttcat cgactttcgg
    19441 agccatattg atgtcaccct ccttttagat caaaaattaa aaaactatac acgtgtgtca
    19501 tttttatagt tcgattataa atgacacgag tgtatagttt caatcttaaa atggaaaacg
    19561 ttgcggattt tccggagcat tctttaccat gtgtgctttt ttccaaaata gatgtttgtg
    19621 ttaaaaacta acggctcctg tttacagcgt attccaagtt cttatacgcc attattctgc
    19681 atagtgctat gacgaatgaa gccaatgaac cttcaaagct aatcaaggca gcggattatt
    19741 gactgacttc ttttacattt ggtgctttca gtttagtatc tgaatgagaa gtcagcaaaa
    19801 aaacaacaac agcaatcgca acccccaacg ctccaatcca ggtaatagag gccaatgata
    19861 cattctctac aaaaataccc cctactcctg cacctgcagc catagccaat tgcatcatcg
    19921 actgattgat gccaagcaag acacctgaca attccggttc tagcgtcgct aagtgatatt
    19981 gctgcgtcgg gccggtagac catgcggcaa acgaccataa tatgaggatg atcaatacgc
    20041 cgatatatga gtgggtgacg agcgacagca aaatcagtgt gatgatatgc aatgtcatcc
    20101 cgctaacaag tgtaaagggc actccccatc tatcagtgct atatccccca aacttcgatc
    20161 caaccaagct cgcgattcca aatataagca aaactccgct aagcaggttg ccgcttatcc
    20221 ctgaaatatt caggaggtac ggtgacaaat aggtgtaagc aatggcatat cccccgagcc
    20281 agaaaaaagt gacggacaat cccatcgcca cttttcgttt cctcaaaagg gaaagctgct
    20341 gaagcaaagg gacgggctta tccccttccg tatgcgggag agtcaagaat ataatgatca
    20401 tggcaattaa ccccaataaa gcaattccgc caaatacaga tttccagccc aacgcttcag
    20461 ctgtcattct tccgagtgga acaccaatga taagagaagc ggtaaatccc atgacgacgg
    20521 tagcgatcgc gctgccctgt ttgccttccg gagcgatctt ggcggcaatc gttaatgcgg
    20581 tgacaacaac cattcccgcc cccaacgcca taataacccg tgctgcaata aaccagccgt
    20641 aaccaggcaa ggcaaaggcc aggatatttc cgagcacaaa caaaccgaga gaatatatca
    20701 ttaatttgcg tctatcgata cttgccgtca acgccataag aatcggtgtg aaaatggcat
    20761 acacgagtga aaagatcgta atgagctggc ccgcggccgc tatggtaatc ccaagtgtat
    20821 gcgcaatatt atccagaata ccggaaatga tgtactctga ggttcccact aaaaaactga
    20881 taatggccaa aatataaatt ttccaggtgt tagacatagt cgttcactcc ttaagttttt
    20941 gcattcacat atcacgaaat accgatacga taattttaaa aataaacaca tcgcaatatg
    21001 tcgatatgta tggtgtaaaa ataaacatct tgagatgttt atttttatat ctccgttttt
    21061 agaaagtcgg ccagtttttt aatggcctct tcatctcttt tgtagtaagt aaacttaccg
    21121 attcgctccg ccttaattaa gccggctctt aacaggatgg cgagatattg ggaagccgtc
    21181 gactgcgtca ttttcaattt gtctgtaatt tggctgacac ataccccgat tgtgttcata
    21241 tcaatccctt catggggtgt aaaatgacga tcaggctcct tcagccattg caaaatctgc
    21301 aaccttgatt cattggataa agctttgaaa atttcaattg gttccatacg gattattata
    21361 tcgtgatata ccgatatgtc aatacgtaat ttaactttgg atgtttgtct taaaaacacc
    21421 cctttggtca agccaaagga gggcatcttc catcaaaatc atctcttttc cggacaaggg
    21481 acgttctcca ttattcattg ttaacaaaat aagaaattag acctttccaa aacgcagttt
    21541 ccgtcgcgct gttctgtccg tggaataacg aagccttgct ttcaaccgct tattcctgct
    21601 cgataaacag ataattctca gtgcgggcca cagtagaaaa cagcaccagg aataccttcc
    21661 atccccggat cggacttccg catctaaact tcagcacttt tccttcatct aaggtaaacc
    21721 ttaatgtttg gcttgtgcac caatcaattt tcacttgaat agcatgttcg ccaggctgta
    21781 aatcaattcg cagccttccg ccatctttga tttttcccat ctcgacacca tcaatcagca
    21841 cagaaaaacc tctcatttta ttaatgtact gtgatgtcct gctaatttca atgtacgtct
    21901 cttgattcac aattacacat ccttaaaata attaagatcc cacacacgga cgccgttaag
    21961 gagcgccttg ccatgccgct gcatgaaccg ataaattcgc tagtttaaac aatttaaagc
    22021 ctatttaagg ttaccaaaaa acgtcacgcg ctccaagtaa gacatcaaaa aaacagctct
    22081 attccctatc aggcccggct ggttcagtgc cattgccaac agaattctcg cttcttattt
    22141 cgattgaaat aaaaaagtac agcattaaaa aatctgcggc tgcagggaac ctcgatttgg
    22201 cgcacatctg ccacattggg gtgaggatat acttttaaaa atttaatcac gcattgtata
    22261 tattgtatat aatgtgtata ttgaggcgta gacaattaaa agaggttttg aaatgaaaat
    22321 tataatttcg aataattcaa agcaacccat ttatgaacaa atttacactc aaattaagga
    22381 tcatattctt gcaaatgaat tgaaaccggg acagccgctg ccttctatgc gccaattagc
    22441 aaaggatatg aatgtaagtc ttattacgtc gaagcgcgcc tatgaagaac tcgagaagaa
    22501 tgggttcatt tattctgtgg tcgggaaagg ctcttttgta tcagttcaga atgacgaaat
    22561 gatgaaggaa ggaaaaatga aagcgattga agagcaattg ttggcagcaa ttaaaaatag
    22621 taaagacatt ggcattaccc ttacagaatt aaaagaattg cttaccattt tatatcggga
    22681 ggaagaatga tggacaatgt aattgaactc cggcatgttc ataaatcgtt cgaatgtttt
    22741 catcttaagg acttttcaat gacggtagaa aaagggtttg tcaccggatt tataggcggc
    22801 aatggtgcag gaaaatcgac aacaattaaa ttgatcatga atttattgca acctgacagc
    22861 gggacgatta aggtgtttgg cttgaattac aaggagcatg agaaagaaat caaacaacga
    22921 atcggttttg tatttgatca caatgtattc tatgaacatt taacatttac cgaaatgaaa
    22981 gaacttataa aaagagccta tgtcaactgg gatgatcaag ttttcaatga ttatgcaaaa
    23041 acatttaact tgccgctaac gaagaaaatc aagacgttct caaaagggat gatgatgaaa
    23101 gcttcattag ccatcgcttt gtcccatcat gcggaattaa ttattatgga cgaaccgacg
    23161 tccgggctgg atccgatttt ccgccgggag ctgttggata tcttgcatca actcattcag
    23221 gatggggata aaacgatctt tttttcgact catattacga ctgatttaga tacgattgca
    23281 gattatatca cgttcattca taaaggagag catatcttta caaaggactt ttatgaaatt
    23341 gaggaagagt atgcgattgt caaaggcgga atggagttat tagacaggga gacggaacag
    23401 gaatttatag cggttcgaaa atcaactcat ggatttgaag cattgactgc gaataaatca
    23461 cgaacagaaa aaatctttgg ggacatggcg ttaatagaaa aaccgactct tgaagatatt
    23521 atgttctata cgaagaaagg agccaaagaa catgttcaac ttaatacgta aggatattgt
    23581 cttgcagaaa aaaacgttgg cggcttcgtt tttggtatta tgtgtttatt taatgttaga
    23641 tatttctcca atctgggttg gggttgtatt tagtatagtt atatcgatgt atgccttttc
    23701 aatagatgaa aagtcttcta tacatatgct tctcaattct ttgccttata cacgaaaaga
    23761 aattgtcagt tcaaagtata ttgtcgtcgt tctctttaca tgtatggtgg ctgcagccat
    23821 atttatcgta aactttatca ttcaccggga acttacgatc tggaaagaca ttttgctaat
    23881 ggtcgccatt gtgatgacag ctgcttcatt catgctgcca ttctgttata aattcaaaag
    23941 taactatctg ttgattgctt ctattgttgc atttggcttg tatatgctaa cgattaactt
    24001 tgttgtccat aatttgaacg atcaaatcag agagttcatt cacatgcttc taaccttaca
    24061 aaatacttct ctgtatctga tcgttgccat atcaattatt acgctgtacg ggtgttcatg
    24121 gcttctgtcg attcggattt atagaaataa agtgttttaa aaaggatcgg gatgctttcg
    24181 acttgccaat cttttttcat cattgacaac tctacatggt cagcctgttt tcattcggag
    24241 tatatcagat aaaaaactgc accgtcacac ttttcgtcag gttgttacgg tgcgagcccg
    24301 gttgaacttc cagcaacagc acttgcctca acgacctatt cctgcttaat aaacgaatac
    24361 tctttctcaa cttggaatat aaggccgtta caatccaaaa atattgtt
//
