LOCUS       NZ_CP021744            21555 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces albireticuli strain MDJK11 chromosome, complete genome.
ACCESSION   NZ_CP021744
VERSION     NZ_CP021744.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces albireticuli
  ORGANISM  Streptomyces albireticuli
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8144417)
  AUTHORS   Wang,Y., Du,B., Ding,Y., Liu,H., Hou,Q., Liu,K., Yao,L. and Wang,C.
  TITLE     Streptomyces albireticuli Genome sequencing and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8144417)
  AUTHORS   Wang,Y., Du,B., Ding,Y., Liu,H., Hou,Q., Liu,K., Yao,L. and Wang,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2017) Department of Mcrobiology, Shandong
            Agricultural University, No.61 Daizong Street, Taian, Shandong
            271018, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 2.3
            Expected Final Version            :: yes
            Genome Coverage                   :: 88.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 07:12:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,975
            CDSs (total)                      :: 6,876
            Genes (coding)                    :: 6,711
            CDSs (with protein)               :: 6,711
            Genes (RNA)                       :: 99
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 165
            CDSs (without protein)            :: 165
            Pseudo Genes (ambiguous residues) :: 0 of 165
            Pseudo Genes (frameshifted)       :: 74 of 165
            Pseudo Genes (incomplete)         :: 97 of 165
            Pseudo Genes (internal stop)      :: 5 of 165
            Pseudo Genes (multiple problems)  :: 9 of 165
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:17:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7840346
            Orig. end                         :: 7861901
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP021744.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21555
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /product="CDPS"
                     /region_number="40"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..21555
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /detection_rules="CDPS"
                     /kind="neighbouring"
                     /product="RiPP-like"
                     /product="CDPS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..10855
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10855
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5855](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5855
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(195..821)
                     /locus_tag="SMD11_RS33380"
                     /old_locus_tag="SMD11_6791"
     CDS             complement(195..821)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004940865.1"
                     /locus_tag="SMD11_RS33380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6791"
                     /product="transcriptional regulator"
                     /protein_id="WP_087929996.1"
                     /transl_table=11
                     /translation="MNRPRTPATDTGLLVLHALRCAGAAGLTRLHLVTGLDESDVESEL
                     IDLGAAGFVTRRSGDFPGWSLTGAGRAAGAERIAGELASAGARKAVAAAYGRFLVLNPE
                     LLDLCTAWQLRTVDGVLGANDHRDPAYDAQVLDRFTDLDRRATPVCAELAAALPRFGRY
                     RVRLAEALGRAASGRLEYVADSTASYHTVWAELHEDLLTTLGMPR"
     cand_cluster    773..21555
                     /SMILES=""
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    773..21555
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10772:11555](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(10773..11555)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="2"
     gene            1025..2137
                     /locus_tag="SMD11_RS33385"
                     /old_locus_tag="SMD11_6792"
     CDS             1025..2137
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009998095.1"
                     /locus_tag="SMD11_RS33385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6792"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_087929997.1"
                     /transl_table=11
                     /translation="MARLTRAQQQERTRAAVLVAARKEFAEYGYAEAKVDRIAERAELT
                     RGAVYSNFTGKRALYLAVLADDAEQARAAAEPPPTSPGTAGQALGVFARLWLERLPFAA
                     DTPGSGHLRLRSLTGVLDTGPARTAMGELLRFEALLLAQALEPHTALRTGTVRRAELAL
                     TLLHGAASLAEHAPGAGDPFDLARAAEHLAGVPVVDDADPPHLPFVGPARPTRDAWTAP
                     GELHDEITGGRIGLDDDGVVVVLGVGRLSAAEEAMRSARPGDKLTFVVVTGDPGETGRL
                     ASLRVTDLIACLRRVFVHEDLPRSRVVFDDTGTVSAAIGRDAVDDSTEVAIRTLGGLIV
                     ARAEGRGAGHAVAGHAIQEGARQRSRASRK"
     misc_feature    complement(2279..2296)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 24.4"
                     /tool="antismash"
     gene            2771..4081
                     /locus_tag="SMD11_RS33390"
                     /old_locus_tag="SMD11_6793"
     CDS             2771..4081
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014696.4"
                     /locus_tag="SMD11_RS33390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6793"
                     /product="phosphatidylserine decarboxylase family protein"
                     /protein_id="WP_087929998.1"
                     /transl_table=11
                     /translation="MTLPTHQVRTAQHIEARYQNSFGRAAGYLPKNRAALDAWLEQFSR
                     DVHEKRSRDAIVRRRSVDDLQRLIERDGIIRMYVSRMIADARVVNADAKDTVRNIPDLL
                     DHLDCIVTSTPRYYPKGDPDRNFFPLSSLFCYMMMTEPGYAVFRDKEFNRALLGILREW
                     CAHLDSPDSRDVLNEEEHGWLSQAAKDEFKLDQFQIDWLAPHGGFASYNTFFHRGLREG
                     ERPIGGEGDARVVVAANDGRVVRIRRNIQRSDDFWAKGQKYSLHDMLDGSDLTDSFIGG
                     DVFQSFLSGADYHRWHAPVTGIVRSARVVEALMFTELEGVWEPSSGTESQVYGASVNTR
                     GLVFIESPAPIGTVCVMPLGMTEISSVTLTVRPGDHVTKGDQLGYFNYGGSSMCLLFQK
                     GAIDEFTVPDNTGDMESGHPIQVNGQIARAFAPKTKA"
     gene            4096..4977
                     /locus_tag="SMD11_RS36040"
                     /old_locus_tag="SMD11_6794"
     CDS             4096..4977
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS36040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_6794"
                     /product="hypothetical protein"
                     /protein_id="WP_199844009.1"
                     /transl_table=11
                     /translation="MAVKKTPRTGRQPAAGPRPSAEKNSCGRPGKDEELHVCMGLNSCA
                     GQDVSGNATMAGTGECATVQHVCHGEGACRGQGGCGYAGDDFEQFHPGEQACRYNGSCA
                     SPINESRVFSGGPLKGRSVWQQARHLFEARMYAAGKAFGPAPGQGVHDTYFPEYDRLVA
                     PRPGASDKAASLFRSSGDNPRCHADVRFPDLQAIARNSAGRHLPGVQVTFTIPADASAV
                     LYFKPEGQKPGSTCKVLTDDKGVATAAPLYAGHTSPADQWVTVTASTPAPPPADTATCD
                     FHVTVLAPEETS"
     gene            5001..5855
                     /locus_tag="SMD11_RS36045"
                     /old_locus_tag="SMD11_6795"
     CDS             5001..5855
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF003818.1"
                     /locus_tag="SMD11_RS36045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6795"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_199844010.1"
                     /sec_met_domain="DUF692 (E-value: 3.4e-94, bitscore: 313.7,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVRTGGTAPHLGFGLGLRGPHIPYVRAHRPPVDFFEIISENYLDP
                     RSDRRRVLDEIAEHYPIVLHGVSLSIGSTDPLDRDYLSRLKRLADAVDTPWVSDHVCWT
                     GVLGVHTHDLLPIPFTEEALAHVVRRARTVQDALERPLVLENPSSYVEFRASTLTEWEF
                     LGRLAEEADCGLLLDVNNVQVSAVNHGFDPETYLTSLPHHRVTQMHLAGHTDYGTHLID
                     THDAEVPGRVWELYRLAVRLTGGAATVIERDDGLPPFRVLEAELDRARSVAATAGTEAG
                     RRG"
     gene            5848..6522
                     /locus_tag="SMD11_RS33400"
                     /old_locus_tag="SMD11_6796"
     CDS             5848..6522
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021364.4"
                     /locus_tag="SMD11_RS33400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6796"
                     /product="DNA-binding domain-containing protein"
                     /protein_id="WP_087930000.1"
                     /transl_table=11
                     /translation="MDDVPRSLVEIQEWMQAALLSPGRAPHLAEVFTASATQSAEERFR
                     VYHRGYRLRLLRCLRQRYPAMSHLLGRELFERFALDYLDANPSRSPVLDTLGDDFPDHL
                     ARTRPDTGDGGPPEVWIDLLIDLARFERDFTAVLDGPDSVDDGPVGGTGSGDGGGARLF
                     EARFPVHRYAAAVRHGQDPEPPGAEPVRLSLTRRDGTVVVHDLTDAGHRAPRATARPST
                     AA"
     gene            6544..7773
                     /locus_tag="SMD11_RS33405"
                     /old_locus_tag="SMD11_6797"
     CDS             6544..7773
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024306.4"
                     /locus_tag="SMD11_RS33405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6797"
                     /product="ferritin-like protein"
                     /protein_id="WP_087930001.1"
                     /transl_table=11
                     /translation="MPHLTKRSAVRTADGITTLDELAQHLADAARIELSTIPPCLTAAY
                     SIKTSGYSQWAQGLSAQRTLIGIAIEEMLHMALVRNVMAGTGCEKVDGQPFRFYDQHNI
                     PVYPGDMLHRVPKLTLHKQRVSTAAVEGFMEVELPESMVTRGSKTEGDTYHTLSELYDE
                     IGKGIVTLNDQIPWNQGEAWKRQYLRGYWNQWGGPPKPLPVIDQGSALDALYVIVEQGE
                     GAPDEQEDSHYQKFTRVRDGLYGIGVVVDDNGQQKFTIDGDEAVWPVTTDATADSFTGP
                     LKTLAQLSDAAYSYVLALLDQLYATPADDPAPRTPNPTSKRYALERGFVAAMQGVLSSV
                     AGILVGTPVGDGKNAAPTFGYYPFGPKPKEDLISLCTDPKLMAAYPQLGGTDGVLHQIN
                     LLPDIGLQGS"
     misc_feature    7105..7107
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7881..8423)
                     /locus_tag="SMD11_RS33410"
                     /old_locus_tag="SMD11_6798"
     CDS             complement(7881..8423)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS33410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_6798"
                     /product="hypothetical protein"
                     /protein_id="WP_087930002.1"
                     /transl_table=11
                     /translation="MGRITVTVEDPVFGDLTIVLDTGEGSVEVSGGRLPRTTLRRVPGT
                     VPTSWPPIGTTDPDSLALTLDGEGEPPALSRGYVNRRTYTVRLPEGGRTYRLVPDDETR
                     SRLMRDKVLLGRLRVSPGGGHVTPVTWRSASKVLPAEAALGYVLAVGLGTGGKQSESGG
                     GAGTAADAVLDILAVWS"
     misc_feature    complement(8160..8162)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    8472..8487
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.1"
                     /tool="antismash"
     gene            complement(8745..9545)
                     /locus_tag="SMD11_RS33415"
                     /old_locus_tag="SMD11_6799"
     CDS             complement(8745..9545)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="SMD11_RS33415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6799"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_087930003.1"
                     /transl_table=11
                     /translation="MADPSTSHLNPVVDATEETDAFDALGGLYEESARLPFREHLEHHS
                     VRKAVGDVTGLDVLDLGCGSGLYTRRLAAWGAARVTGVDCSAGMLATARAVERARPVGA
                     RYVRADATRPVTDGAEGTADLVLSVYVLCYARSERELTAVLTTARRALRPTGGRLVAVT
                     LNPDYGRGTAYYAPYGFTLTQPDEREGAPVTLDATLPSGGRLHVTAHWWSRDTYERAAR
                     AAGFAGTAWTPMAVSPRGRELLGDAYWSAYLRAPQALILEATAL"
     gene            complement(9553..10761)
                     /locus_tag="SMD11_RS33420"
                     /old_locus_tag="SMD11_6800"
     CDS             complement(9553..10761)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="SMD11_RS33420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6800"
                     /product="cytochrome P450"
                     /protein_id="WP_159395441.1"
                     /sec_met_domain="p450 (E-value: 1.5e-15, bitscore: 55.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSTAPSLPLRYPFALGPMGTPPPVVHWARAHRPVCPVLLPSGAR
                     AWMLTRGDDIRSVLADRRFSRGLAFAGAPRVVGEDVTAVPGSLFNLDPPDHTRVRQVLA
                     PYYTRTAAARCRPVIRALVGEALDKVARGPNPRDLMEAFAAPLPPMLACALLRIPRQLW
                     EEAAAGFAAQMSFADDSADVAAATAAVSDFTRRAVGLRRADPSGRDDPLGALLTAYEAG
                     VITEEELHGTASYLLVTGVESLVSPMATGPLTLLLHRGQLLRCLADPALWPGAVEEVLR
                     YHHNGVLGLPRVAVEDVELHGTLIREGDAVCATMLGATWDPAHYRDPARFDVQRRENAD
                     PTFGAGPHYCLGAAQARTALTLAYRALFERLPGLELAVSPREIAWDTTSMFVRPAALPV
                     VWR"
     gene            complement(10773..11555)
                     /locus_tag="SMD11_RS33425"
                     /old_locus_tag="SMD11_6801"
     CDS             complement(10773..11555)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04539.1"
                     /locus_tag="SMD11_RS33425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6801"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_159395442.1"
                     /sec_met_domain="CDPS (E-value: 9.9e-55, bitscore: 184.2,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METEPPFRTLPYTGQCGRHLMAAEHALIGLSPWNGYFTARRVETL
                     VEWAAGAFRRVDVFIPSYEAAYTLIAAGVAPAVAVGRARRAVKKLRGPAQRALLRAGCG
                     EGRVHTGTSLAARPRYLRLRRTVERTYHQDPGVRAVCRAVGRSAVAGALAAHARTASRP
                     EPEREPGLSEERLDTAARYAWAELPVMLDSPGIFGVSSSVLVYHRRTPLMESLLQDDSA
                     LRPAPGQGFVVVAPAGRASPGDAAGDARGARRRRAAAL"
     gene            11831..12364
                     /locus_tag="SMD11_RS33430"
                     /old_locus_tag="SMD11_6802"
     CDS             11831..12364
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS33430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_6802"
                     /product="hypothetical protein"
                     /protein_id="WP_087930006.1"
                     /transl_table=11
                     /translation="MLGDKLNPGELVRFGEGRGEYHLTSPAATALQEAGIVLKALSPGE
                     AHSNGNGGVSLPITGGDIDPDLSRGKLHCEGGFDFTHSDGRRLEIRDHWADAATSRYCA
                     TVAGREVPWLAFRLDPQALSLTSGRLTAKLPVTLTDEGAALFTEVLGASPVSPGEHLFD
                     TEGQVSLATMPLGL"
     gene            12814..14475
                     /locus_tag="SMD11_RS33435"
                     /old_locus_tag="SMD11_6804"
     CDS             12814..14475
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996562.1"
                     /locus_tag="SMD11_RS33435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6804"
                     /product="allantoin permease"
                     /protein_id="WP_234366290.1"
                     /transl_table=11
                     /translation="MSSTEQRSKEPAVREETPHARAGHAARETLEDYTLRFAPRGYRRW
                     TPMVVATTAMGGIAYLADFSIGAGIGLTHGTGNALAAILVAAVVIFVTGFPLAYYGARY
                     NIDLDLITRGSGFGYYGSVLTSVIFASFTFVFFALEGSIMAQGLKLGLGLPLWLGYLVS
                     TFMVIPLVVYGMKALSRLQVWTTPVWLLLMVGPLVYLVATDPGTVDRWLSYAGTDGQGG
                     VNTASVLLGSGVCLSLIAQIGEQIDYLRFMPPRTDANRRAWWTAVVVAGPGWVVLGALK
                     QATGVFLAVYVIASVGPAAATEPVQQFKAAFDAMMPSWLVVPLAVVLVVISQIKINVTN
                     AYSGSLAWTNSFTRLTGRYPGRMVFVLLNLAFALALMEADMFSFLNRVLSFYSNCAIAW
                     VVTVATDIIVNKYLLKLSPHAPEFRRGMLYAVNPVGTVAFVAASGLSIALYFHALGDTL
                     QPYSPVAAALIAFVLTPLMAVLTKGRYYLRRTTDGIDEPLLDADGNPSATLYECHVCRQ
                     EFERPDVAACRTHDAVVCSLCLSTDRIGDHVLPAGG"
     gene            complement(14502..15293)
                     /locus_tag="SMD11_RS33440"
                     /old_locus_tag="SMD11_6805"
     CDS             complement(14502..15293)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823047.1"
                     /locus_tag="SMD11_RS33440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6805"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_087930007.1"
                     /transl_table=11
                     /translation="MATERSTADILDAAVHVREAARSATSGATGVDTVLAALSEVMEYD
                     HASLSRWDPLRRRHTTLAGSYPDDATAYIETRLHHDPVFPVLRSPARGGLWLRDVPPRL
                     LAASPGFQDVLSPLGIEDGVAQCLFAADGRYVGMLNVSTRRPRRTPDPARAVVTLLTEA
                     LAAAVARHAGPRPEEAVTAGPAADARHPGTGRPGGLSPRELQVLAELTAGRTNREIAER
                     LYVTPRTVGTHIEHILTKLGVPNRAAAAGRAAAWGIEPAAG"
     gene            complement(15325..17028)
                     /locus_tag="SMD11_RS33445"
                     /old_locus_tag="SMD11_6806"
     CDS             complement(15325..17028)
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823048.1"
                     /locus_tag="SMD11_RS33445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6806"
                     /product="amidohydrolase"
                     /protein_id="WP_087930008.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 6.6e-11, bitscore:
                     40.7, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTYADLVFLGGRVVTVDAGFSLASALAVTGGVISAVGGRDDVAP
                     LVGPGTRVVDLRGATLLPGINDSHLHGCAFGMATPPLSLDLGHPAVSSLADVAEAVREA
                     AGRLPGGQWITGHGWDTGYLDECVSEPSRLPSRRDLDAVSPDHPVVLYSFSGHATWVNS
                     KALELIGIDRHTVAPPGGAIVADEAGEPTGLLHEGAQALVQNALPPLSRQERADAIRSA
                     LATLARLGVTSYTEPGLGPGGAGITRGTLGTETLDVYRELLAEGELTARVGVLLLPTGM
                     TSTAEEFARTLDALSVSGDADPRRLAIHGVKVFADGVVPNKTAWMHEPYVGGGCGSLCV
                     GGGSDTERAAEIGAVIRHAHAAGYQLGVHVTGDRACDTVADAFAAAVAEHPRPDARHYV
                     IHGDFLTAYSMKVLAAHGFGVNMNPTIKWTVADMEEDFVGAERAAYAWPYRDAIDAGVR
                     VASGSDAPVTYPDWRQGVATMMLRESKATGRVSGPGQRIGLAEAIRTYTIDAAWQDFAD
                     DWKGSLEPGKVADLCVLDGDLLTADPHDIPEMPVVLTVMDGRVVHDTLRD"
     misc_feature    17129..17142
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.42"
                     /tool="antismash"
     gene            17275..17886
                     /locus_tag="SMD11_RS33450"
                     /old_locus_tag="SMD11_6807"
     CDS             17275..17886
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009080410.1"
                     /locus_tag="SMD11_RS33450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6807"
                     /product="GNAT family protein"
                     /protein_id="WP_087930009.1"
                     /transl_table=11
                     /translation="MLRIDFPIATTRLTLRPFRPEDAEDVGDYQGRPDVARFMRWEPRG
                     AEDVRVAVEQMTRETGLVSDGDCLSLAVVEPGTGKVVGQVELVLLSAEHRQGELGYVFH
                     PAHQGKGFATEAASAVLRLGFEELGLHRVIGRCHADNTASAGLLERLGMRREARLIGTE
                     FFKGAWRDDLVYAMLQREWQAPAARRDTAHAPEAGTGARA"
     gene            complement(17946..>18122)
                     /locus_tag="SMD11_RS33455"
                     /old_locus_tag="SMD11_6808"
                     /pseudo=""
     CDS             complement(17946..>18122)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014133799.1"
                     /locus_tag="SMD11_RS33455"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6808"
                     /product="prolyl aminopeptidase"
                     /pseudo=""
                     /transl_table=11
                     /translation="PAVLVHGRHDMGSPVPTAWELAKVWPDARLHIFEDSGHAGSDAMQ
                     HAARAAIEEFKNR"
     gene            complement(18125..18637)
                     /gene="ectA"
                     /locus_tag="SMD11_RS33460"
                     /old_locus_tag="SMD11_6809"
     CDS             complement(18125..18637)
                     /EC_number="2.3.1.178"
                     /GO_function="GO:0033816 - diaminobutyrate
                     acetyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ectA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606559.1"
                     /locus_tag="SMD11_RS33460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6809"
                     /product="diaminobutyrate acetyltransferase"
                     /protein_id="WP_087930010.1"
                     /transl_table=11
                     /translation="MTGSLSEKTEVRYRTPTPKDAVPVWRMVVDEPMLDDNSSYHYTLW
                     FRDFAKTSMVATAGDDIVGFMTGYRRPDEPDTFFIWQAAVKPGSGISGLGIDILANAID
                     LQLAAGAKYVETSVSEQNKPITMLLRMVANAYDADIHTEPLFLAEELPGGDHDEILYRI
                     GPLNPRA"
     gene            complement(18663..19337)
                     /locus_tag="SMD11_RS35655"
                     /old_locus_tag="SMD11_6810"
     CDS             complement(18663..19337)
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: ACPS (98-159). E-value: 2.9e-10. Score:
                     32.0. Matches aSDomain:
                     nrpspksdomains_SMD11_RS35655_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013786.4"
                     /locus_tag="SMD11_RS35655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6810"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_159395443.1"
                     /transl_table=11
                     /translation="MPVRARPGWEGLLAPDEAARAEAIPEGGRRDLFVTSRATQRLIAC
                     RYTGSPPRQVRVERTCERCGAGHGRPRVVGAGYEYSVAHTRHRVLVGVVAYGLVGIDLE
                     TIAGPGVPQGLLARTTTPDERVALSQLPPHELPGAFTRLWSRKEATVKLTGHGLAARLD
                     RIGVRGDLALPHGSPAEDWPSSEVHLLDVFVEGHAAAIASTHRITDVRAIAGRPGPHRL
                     TL"
     aSDomain        complement(18861..19043)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SMD11_RS35655_ACPS.1"
                     /evalue="2.90E-10"
                     /label="SMD11_RS35655_ACPS.1"
                     /locus_tag="SMD11_RS35655"
                     /protein_end="159"
                     /protein_start="98"
                     /score="32.0"
                     /tool="antismash"
                     /translation="VGIDLETIAGPGVPQGLLARTTTPDERVALSQLPPHELPGAFTRL
                     WSRKEATVKLTGHGLA"
     gene            complement(19490..>21211)
                     /gene="cmlS"
                     /locus_tag="SMD11_RS33470"
                     /old_locus_tag="SMD11_6811"
                     /pseudo=""
     CDS             complement(19490..>21211)
                     /codon_start=1
                     /gene="cmlS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (halogenases)
                     conventional flavin-dependent halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119: halogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF033113.0"
                     /locus_tag="SMD11_RS33470"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_6811"
                     /product="chloramphenicol-biosynthetic FADH2-dependent
                     halogenase CmlS"
                     /pseudo=""
                     /sec_met_domain="Trp_halogenase (E-value: 4.6e-29,
                     bitscore: 100.2, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ETPMNRSTVAIIGAGPAGCTAALTLHKLGHEPVVFERDSFPRYRI
                     GESLLPGSLSIFDRLGLQDRIDAAGFVEKPSATFLWGQDEAPWTFSFTTPKTSPWVFDH
                     AIQVKREEFDQLLLDEVKERGIEVHENTPVSHVDIADPGKVSLTAGQGGDARQVECDFV
                     IDAGGANGPLARKLKVRRYDEFYKSFAIWSYFRCPDPFEGDLNGTTYSITFEDGWVWMI
                     PLKGDLYSVGLVVDRSKSSEVKERGPDRFYRESLAKAVRAKEILGDAEMVDEVRVVHDW
                     SYDSEVYSGGRYFLSGDSACFTDPLFSQGVHLATQSAVSAAAAIDRITRREEETEEVHA
                     WYNRAYRETYEQYHEFLASFYTLASFTEPESEFWVRRRISESDDGRLNRKRWFERLAAS
                     SKDGTWSVTDFRDRATTMMSIGRHQRMELSDEFTDDELNPARVRWISQLTKRLNRIKRL
                     QWNGKEVALKPYYKVDPETFRLESKQVLANEEGRDMIKWPLEEKHRQIFSRLLKEEVGY
                     KELIRELSEADQQELSSQIVIRLMEAGLLTGYDKNGEEVFIQDRLRFDGVGTEYEV"
ORIGIN
        1 ggccgccgcg agttcgtcgt cgaacccgtc gggacggcgt ccgtcccgga ggaaggcgcg
       61 gcacgcctcg gtggtggcga cgaacccggg cggcacccgc agcccgaggc ggtgcaggag
      121 gacgaggccg tgcgccttgc cgcccagcgt ctccgccgtc tcctcggcct gggcggagat
      181 cgtacggatc catctcatcg cggcatcccg agcgtggtga ggaggtcttc gtgcagctcc
      241 gcccacacgg tgtggtacga cgcggtgctg tcggccacgt actccagccg gccggaggcg
      301 gcgcggccga gggcttcggc gaggcggacg cggtaccggc cgaaccgggg gagcgcggcg
      361 gccagttcgg cgcacacggg ggtggcgcgg cggtcgagat cggtgaaccg gtcgaggacc
      421 tgggcgtcgt aggcggggtc gcggtggtcg ttggcgccca ggacgccgtc gacggtgcgg
      481 agctgccacg cggtgcagag gtcgagcagc tccgggttga gcacgaggaa ccggccgtac
      541 gccgccgcca cggccttgcg ggcaccggcg gacgccagct cgccggcgat ccgctcggcg
      601 ccggcggcgc ggcccgcgcc cgtgaggctc cagccgggga agtcgccgga cctccgtgtg
      661 acgaatccgg cggcgccgag gtcgatgagc tcggactcga cgtcggactc gtcgagccct
      721 gtgaccaggt ggaggcgggt gaggccggcg gcgccggcgc agcgcagggc gtgcagcacc
      781 agcaggccgg tgtccgtggc aggggttcgg ggccggttca cgtcttgccc ttctggtggg
      841 aggagcggac ggcatcgtca ctccgggcgg ggcgggccgt aggcgcggag cgcgagtgga
      901 cggaagctcg aaccctttgc ccgtacatgt ccatgcctcc attccgatgc ccacagcatt
      961 ccgatgacgt catcatctgg atgccgtctg tactatgaca cggcggaagt gaaaggggcc
     1021 agggatggcg aggttgaccc gcgctcagca gcaggagcgg acacgcgcgg ccgtgctggt
     1081 cgcggcccgg aaggagttcg ccgagtacgg atacgccgag gccaaggtcg accggatcgc
     1141 cgagcgcgcc gaactgacca ggggcgcggt ctactccaac ttcaccggca agcgcgcgct
     1201 ctacctcgcg gtgctggccg acgacgccga acaggcccgg gccgccgccg aaccgccgcc
     1261 gacgtcaccg ggcaccgccg gacaggcgct cggcgtcttc gcccggctct ggctcgaacg
     1321 cctgcccttc gccgccgaca ccccgggcag cggccatctc cggctgcgct cgctgaccgg
     1381 ggtcctcgac accggccccg cccggacggc catgggcgaa ctcctccggt tcgaggctct
     1441 gctgctcgcc caggcactcg aaccgcacac cgcgctgcgc accgggacgg tacgacgggc
     1501 cgagctggcc ctgaccctgc tccacggcgc ggcgagcctc gccgagcacg ctcccggagc
     1561 cggcgacccc tttgatctgg cccgcgccgc cgagcacctg gccggcgttc ccgtcgtcga
     1621 cgacgcggac ccgccccacc tgcccttcgt cggtcctgcc cggccgacgc gggacgcgtg
     1681 gacggccccc ggcgaactcc acgacgagat caccggcggt cggatcggtc tcgacgacga
     1741 cggcgtggtg gtcgtactgg gcgtcggacg cctgtccgcg gccgaggagg cgatgcgctc
     1801 ggcgcggccg ggcgacaagc tgacgttcgt cgtcgtgacc ggcgacccgg gcgagaccgg
     1861 ccgcctggcc agcctccggg tcaccgacct catcgcctgt ctgcgacggg ttttcgtgca
     1921 cgaggacctg ccgcggtcac gcgtcgtctt cgacgacacc ggtacggtct ccgccgccat
     1981 cggccgggac gcggtcgacg actccaccga ggtcgcgatc cggaccctcg gcggtctgat
     2041 cgtggcccgc gcggagggac gtggcgcggg ccatgcggtg gccggccacg ccatccagga
     2101 gggcgcgcgg cagcggagcc gcgcgagccg gaagtgacac gggtcgggca gggcggggtc
     2161 cgtcacggga cgatctcgcg gtgacacccc ggtacgcgtc gcgcccggcg cgcccgacga
     2221 ggaacttcgg ccagtgggga ggctgttgag ggtgccgcgt gcggtccggc gatttcgtta
     2281 tccgctatag cggatgcctt gacgggttta ggtccgctag gtaacgttcc ggatactccg
     2341 gccatttggc ccgcgcgggc ggtaccatcc accgcccgtc gcgccgcaca ctcacgcggc
     2401 tggtacgggg gtgcagccgc gtgagtgtgg tggtatcggg tacgcacccg gccatctcgg
     2461 gcacccgggc ccgcgcgggg cgacaggccg ctcacggggg cgcgaccggc ggcgacttac
     2521 aggccaagct tcaggggacg aagtgtcttc aagtcctgcg tgtcgcccgc cgaccgccca
     2581 tcggcgccgc gccgaacagc cgcactgaac aggcggaaga ggagcggccc tttcggaacc
     2641 gccgtatccc gacacacagt tcgcgccacc gatccgggtc ctgttcccgg cgtcatgccc
     2701 tgaggggggt gttgagcggt ctcggcggcg tccgggaacc tgagcccctc gttcgaagga
     2761 ggggaccctc atgaccctgc ccacccatca ggtccgtacc gcgcagcaca tcgaagcgcg
     2821 ctaccagaac tcgttcggcc gcgccgccgg ctacctgccg aagaaccgcg cggcactgga
     2881 cgcgtggctg gagcagttca gccgggacgt ccacgagaag cgctcccgcg acgccatcgt
     2941 ccggcgccgg tccgtcgacg acctccagcg gctgatcgag cgggacggca tcatccgcat
     3001 gtacgtgagc cggatgatcg ccgacgcccg cgtcgtcaac gccgacgcca aggacacggt
     3061 gcggaacatc ccggatctgc tcgaccacct ggactgtatc gtcaccagca cccccaggta
     3121 ctacccgaag ggcgaccccg accggaactt cttccccctg tcgtccctgt tctgctacat
     3181 gatgatgacg gagcccggct acgcggtgtt ccgcgacaag gagttcaacc gggcgctgct
     3241 gggcatcctg cgcgagtggt gcgcgcacct ggacagcccc gacagccggg acgtcctgaa
     3301 cgaggaggaa cacggctggc tgtcgcaggc cgccaaggac gagttcaagc tcgaccagtt
     3361 ccagatcgac tggctcgccc cccacggtgg gttcgcctcc tacaacacgt tcttccaccg
     3421 cgggctcagg gagggggagc gcccgatcgg cggcgagggc gacgcccgcg tcgtcgtcgc
     3481 ggccaacgac ggccgggtcg tgcggatccg caggaacatc cagcgcagcg acgacttctg
     3541 ggccaagggc cagaaatact ccctccacga catgctcgac ggcagcgacc tcaccgactc
     3601 gttcatcggt ggtgacgtct tccagtcctt cctctccggc gccgactacc accgctggca
     3661 cgcgcccgtc accggcatcg tccgcagcgc ccgcgtggtc gaggccctca tgttcaccga
     3721 gctggagggc gtgtgggagc ccagctccgg gacggagtcc caggtctacg gggcctcggt
     3781 caacacccgg gggctggtgt tcatcgagag ccccgcgccc atcggcacgg tgtgcgtcat
     3841 gcccctcggc atgacggaga tctcctccgt cacgctgacg gtgcgccccg gcgaccacgt
     3901 caccaagggc gaccagctgg gctacttcaa ctacggcggc tccagcatgt gtctgctgtt
     3961 ccagaagggc gccatcgacg agttcaccgt gccggacaac accggtgaca tggagagcgg
     4021 gcacccgatc caggtcaacg gacagatcgc ccgagccttc gcgcccaaga ccaaggcata
     4081 ggaggggagg acaccatggc ggtgaagaag acccctcgga ccgggcggca gccggctgcc
     4141 ggaccgcgac cgtccgccga gaagaactcc tgcggccggc cgggcaagga cgaggagctc
     4201 catgtctgca tgggcctcaa ctcctgtgcg ggccaggacg tcagcgggaa cgccaccatg
     4261 gccggcacgg gcgagtgcgc cacggtgcag cacgtgtgcc acggcgaggg agcctgccgc
     4321 ggtcagggcg gatgcgggta cgcgggagac gacttcgaac agttccaccc gggcgaacag
     4381 gcgtgccggt acaacggcag ctgcgccagc cccatcaacg agagccgggt cttctccggc
     4441 ggcccgctga agggcaggag cgtctggcag caggcgcgcc acctcttcga ggccaggatg
     4501 tacgcggcgg gcaaggcgtt cggcccggca cccgggcagg gcgtccacga cacctacttc
     4561 cccgagtacg accgcctcgt ggccccgcgg cccggtgctt ccgacaaggc ggccagcctg
     4621 ttccgctcgt cgggcgacaa cccccgctgc cacgcggacg tacgcttccc cgacctccag
     4681 gccatcgcgc ggaacagcgc gggcaggcac cttccgggtg tccaggtcac gttcaccatt
     4741 ccggcggacg cgtcggccgt cctgtacttc aagccggagg ggcagaaacc gggcagcacc
     4801 tgcaaagtcc tgaccgacga caagggcgtg gccaccgccg caccgctcta cgccggtcac
     4861 accagccccg cggaccagtg ggtgaccgtc accgccagta cccccgcccc gcccccggcc
     4921 gacacggcga cgtgcgactt ccacgtgacg gtcctggcgc ccgaggagac gtcatagcgc
     4981 cgcgggaggc ggccggaacg gtggtacgga ccggtggcac ggccccgcac ctcgggttcg
     5041 ggctcggcct ccgcgggccg cacatcccct atgtccgcgc gcaccggccg cctgtcgact
     5101 tcttcgagat catctccgag aactacctcg acccccgctc cgaccgccgc cgcgtcctgg
     5161 acgagatcgc cgagcactac ccgatcgtcc tgcacggggt gtcgctgtcg atcggcagca
     5221 ccgacccgct cgaccgcgac tacctgagcc ggctgaagcg actggcggac gcggtggaca
     5281 ccccttgggt gtcggaccac gtgtgctgga ccggcgtgct cggtgtacac acccacgacc
     5341 tgctgccgat ccccttcacc gaggaggcgc tggcacacgt cgtacggcgc gcccgcacgg
     5401 tccaggacgc cctggagcgc ccgctcgtcc tggagaaccc cagcagctac gtcgagttcc
     5461 gcgcgtcgac cctcaccgag tgggagttcc tgggccggct ggcggaggag gccgactgcg
     5521 gtctgctgct ggacgtcaac aacgtccagg tctccgccgt caaccacggc ttcgacccgg
     5581 agacgtacct cacgtccctg ccgcaccacc gggtgacaca gatgcacctg gccgggcaca
     5641 ccgactacgg gacgcacctc atcgacaccc acgacgccga ggtacccggc cgggtctggg
     5701 agctgtaccg gctcgccgtg cggctcaccg gaggagccgc caccgtcatc gaacgcgacg
     5761 acggcctccc gcccttccgc gtcctggagg ccgaactcga ccgggcgagg tcggtggcgg
     5821 ccaccgccgg gacggaggcc ggtcgccgtg gatgacgtcc cgcgctcact cgtggagata
     5881 caggagtgga tgcaggccgc gctcctgtcg ccgggccgcg ccccgcacct ggccgaggtg
     5941 ttcaccgcgt ccgccacgca gtcggccgag gagcgcttcc gcgtctacca ccgcggctac
     6001 cgcctccggc tgctgcgctg cctgcggcag cggtaccccg cgatgtcgca cctgctgggc
     6061 cgggagctct tcgaacggtt cgccctggac tacctggacg cgaacccttc gcgctccccg
     6121 gtcctggaca cccttggcga cgacttcccg gaccacctgg cccgtacccg cccggacacc
     6181 ggcgacggcg ggccgcccga ggtgtggatc gacctgctga tcgatctggc ccggttcgag
     6241 cgcgacttca ccgccgtcct cgacgggccc gacagcgttg acgacggtcc cgtcggcgga
     6301 accggcagcg gtgacggcgg gggcgcgcgg ctcttcgagg cccgcttccc cgtccaccgg
     6361 tacgcggccg ccgtccgcca cgggcaggac ccggaaccgc ccggcgccga gccggtccgg
     6421 ctctcgctga cccgccgcga cggcaccgtc gtcgtccacg acctgaccga cgccggccac
     6481 cgggccccgc gcgcgacggc ccggccgtcc acggccgcct gacgtccgta ctggaggatc
     6541 tccatgcccc acctcacgaa gcgctcggcc gtccggacgg ccgacggcat caccaccctc
     6601 gacgaactcg cccagcacct ggccgacgcg gcccgcatcg aactgtccac catcccgccc
     6661 tgcctcaccg ccgcgtactc catcaagacg tcgggctact cccagtgggc ccagggcctc
     6721 tcggcgcagc gcaccctcat cggcatcgcg atcgaggaaa tgctgcacat ggccctggtg
     6781 cggaacgtca tggccggcac cggctgcgaa aaggtcgacg gacagccgtt ccgcttctac
     6841 gaccagcaca acattcccgt ctaccccggt gacatgctcc atcgcgtccc gaagctcacc
     6901 ctgcacaagc agcgcgtctc gacggccgcc gtggagggct tcatggaggt cgaactcccc
     6961 gagagcatgg tgacgcgggg ctccaagacg gaaggggaca cgtaccacac gctcagcgaa
     7021 ctgtacgacg agatcggcaa gggcatcgtc acgctgaacg accagatccc gtggaaccag
     7081 ggcgaagcct ggaagcggca gtacttacgc ggctactgga accagtgggg cggcccgccc
     7141 aagcccctcc cggtcatcga ccaggggagc gccctggacg ccctctacgt catcgtggag
     7201 cagggcgagg gcgcccccga cgagcaggag gactcccact accagaagtt cacccgcgtc
     7261 cgggacggcc tctacggcat cggcgtcgtc gtggacgaca acggtcagca gaagttcacc
     7321 atcgacgggg acgaggccgt ctggcccgtg acgacggatg ccacggcgga ctcgttcacc
     7381 ggtccgctca agacactggc ccagctctcg gacgccgcct acagctacgt cctggcactg
     7441 ctggaccagc tctacgccac cccggcggac gaccccgccc cccgtacgcc gaatcccacc
     7501 tccaagaggt acgccctgga gcggggcttc gtcgccgcga tgcaaggagt cctctcttcc
     7561 gtcgccggca tcctcgtcgg caccccggtc ggtgacggga agaacgccgc ccccacgttc
     7621 ggctactacc ccttcggccc gaagcccaag gaggacctca tctccctgtg caccgatccg
     7681 aagctgatgg cggcgtaccc ccaactgggc gggaccgacg gcgtcctgca ccagatcaac
     7741 ctgctccccg acatcggcct ccagggcagc tgatctctga gccgaggtgt atttgcgact
     7801 tcccttccgc gcctgggagg gaagtcgcag ccgattccgg cacgggggcc ggatgccggt
     7861 tgactcgcgt cgagtgacct ctacgaccag accgcgagga tgtcgagcac cgcatccgcc
     7921 gccgtcccgg caccgccgcc gctctccgac tgcttcccac ccgtgccgag gcccacggcc
     7981 aacacgtagc cgagggcggc ctcggcgggc aggaccttgg aggcgctgcg ccacgtgacc
     8041 ggggtgacgt gtccgccgcc gggggagacg cggagtctgc cgaggaggac cttgtcccgc
     8101 atgagacggc tacgcgtctc gtcgtcgggg acgagacggt acgtccgccc gccttcgggt
     8161 aagcgcacgg tgtaggtgcg gcggttcacg taccccctgc tcagggccgg cggctcaccc
     8221 tcgccgtcga gggtgagggc gagcgagtcg gggtcggtgg tgcctatggg cggccatgac
     8281 gtgggcactg tgccggggac acggcgcagc gtcgtccggg gcagccggcc accactgacc
     8341 tcgacggagc cctcaccggt gtccaggacg atggtgaggt ccccgaagac ggggtcctcg
     8401 acggtgacgg tgatccggcc catggtgctc cttcgcgtgc ggtgcggctg ccgagggggc
     8461 aggcaccctt aaatgatcat cgatattctc gcggacggac acgcccccgc ggacgggcgg
     8521 ccgtcactct caccaccgtc ctcccgcttc gaggccggcc cgtgaacggc ctggcagccc
     8581 ggggcgggtc gatgccgtga tcacaccacc atttcggcaa gggcttcccg atccttgtcg
     8641 gttacggcag cgcgagctcc tggaggtggg cggtcgcgcc gagaccgcga agccgctgaa
     8701 ggccggtcgc cgcgttcggc ggggagaccg gcgcacagga ggggctacag cgcggtcgct
     8761 tccaggatca gtgcctgcgg tgcgcggagg tacgcggacc agtaggcgtc cccgaggagt
     8821 tcccggcctc ggggtgacac ggccataggt gtccaggccg tgccggcgaa ccctgccgcg
     8881 cgggcggctc tttcgtaggt gtcgcgcgac caccagtgcg cggtgacgtg caaccggccg
     8941 ccgctgggga gggtcgcgtc cagggtgacg ggggcgcctt cccgctcgtc cggctgcgtc
     9001 agggtgaagc cgtacggggc gtagtaggcg gtgccccgcc cgtagtccgg gttcagcgtg
     9061 acggcgacga ggcggcctcc ggtgggacgc agcgcgcggc gtgccgtggt gaggacggcg
     9121 gtcagctccc gctcggagcg ggcgtagcac aggacgtaga cactcaggac gaggtcggcg
     9181 gtgccttcgg cgccgtccgt gaccggccgg gtggcgtcgg cgcgcacgta ccgggcgccg
     9241 accggtcgtg ctcgttcgac ggcccgtgcc gtggcgagca tgcccgcgga gcagtcgacg
     9301 ccggtgacgc gggccgcgcc ccaggccgcc aggcggcggg tgtagagccc cgagccgcat
     9361 ccgaggtcga ggacgtcgag gcccgtgacg tcgccgacgg ccttccggac cgagtggtgc
     9421 tccaggtgtt cgcggaacgg cagccgggcg gattcctcgt agagaccgcc cagggcgtcg
     9481 aaggcgtccg tctcctcggt cgcgtccacc accgggttca ggtggcttgt gctcgggtcg
     9541 gccataaggg gttcacctcc agacgacggg gagggcggcg ggccgcacga acatggacgt
     9601 ggtgtcccag gcgatctccc ggggcgacac ggcgagctcc aggccgggca gccgctcgaa
     9661 cagggcgcgg taggcgaggg tcagagcggt acgtgcctgg gcggcgccga ggcagtagtg
     9721 ggggcccgcc ccgaaggtgg ggtcggcgtt ctcccgccgc tggacgtcga accgggcggg
     9781 gtcgcggtag tgggcggggt cccaggtggc gccgagcatc gtggcgcata cggcgtcgcc
     9841 ctcccggatg agggtgccgt gcagttcgac gtcctccacg gcgacgcgcg gcagcccgag
     9901 gacgccgttg tggtggtagc gcagcacctc ctcgaccgcg cccggccaca gggccgggtc
     9961 cgcgaggcag cgcaggagct gtccacggtg gagcaggagc gtcagggggc cggtggccat
    10021 gggggagacc agcgattcca cgccggtgac gaggaggtag gaggccgtcc cgtggagctc
    10081 ctcctcggtg atgacgccgg cctcgtaggc cgtcagaagc gcgcccaggg ggtcgtcgcg
    10141 gccggacgga tcagcgcggc gaaggccgac ggcccgccgc gtgaagtcgc tgacggccgc
    10201 ggtcgcggcg gccacgtccg cgctgtcgtc ggcgaagctc atctgcgcgg cgaaccccgc
    10261 cgcggcctct tcccacagct gccggggaat ccgcaggagc gcgcaggcca gcatgggtgg
    10321 gaggggcgcg gcgaaggcct ccatgaggtc gcgggggttg gggccgcggg ccaccttgtc
    10381 gagagcctcg ccgaccagcg cgcggatcac cggccggcaa cgcgcggccg ccgtgcgcgt
    10441 gtagtagggg gcgagcacct ggcggacccg ggtgtggtcg ggcgggtcga ggttgaagag
    10501 ggaaccgggc acggcggtga cgtcctcgcc gaccacccgg ggagcccccg cgaaggcgag
    10561 cccgcgcgag aagcgccggt cggccaggac ggagcggatg tcgtccccgc gcgtgagcat
    10621 ccaggcccgt gcccccgacg gcaacaggac ggggcagacc ggccggtggg cccgcgccca
    10681 gtggacgacg ggcggcggcg tgcccatggg gccgagggcg aacgggtagc gcagcggcag
    10741 ggaaggcgcg gtcgacggca tcggcaggac ggtcacagag ccgcggccct ccgacgccgt
    10801 gcgccccgtg cgtctcccgc cgcgtcgccg ggggacgccc gcccagcggg tgcgacgacg
    10861 acgaagccct gccccggggc gggccgcagc gcggagtcgt cctggaggag ggactccatg
    10921 agcggtgtgc gccggtggta gacgaggacc gaggaggaga cgccgaagat cccgggcgag
    10981 tcgagcatga ccggcagctc cgcccaggca taccgggccg cggtgtccag tcgctcctcg
    11041 gacagccccg gttcccgctc cggctcgggc cgcgacgcgg tccgcgcgtg cgcggcgagc
    11101 gctccggcga cggcggaacg gccaacggcc cggcacaccg cccggacgcc cgggtcctgg
    11161 tggtacgtgc gctccaccgt gcgacgaagc cgcaggtatc gcggccgtgc cgccagagag
    11221 gtgcccgtat ggaccctgcc ctcaccgcac ccggcccgca gaagcgcgcg ctgcgccggc
    11281 ccgcggagct tcttgaccgc ccggcgcgcc cgcccgaccg ccacggccgg tgccactccg
    11341 gccgcgatca gcgtgtaggc cgcctcgtag ctcggaatga acacgtccac cctgcggaag
    11401 gcgccggcgg cccactccac cagcgtctcg acgcgccgcg ccgtgaagta gccgttccac
    11461 ggtgacagac cgatcagggc gtgctcggcc gccatgaggt ggcgcccgca ctgtccggtg
    11521 taggggagcg tgcgaaaagg gggttcggtc tccatggggc tccgtggggt cttcgtgggt
    11581 ctggtggggt ctccatggcg gggcggaccg tcccgatgac gcattccgaa gatcgcagtc
    11641 cgatggggaa atggtgacgc aacgcccacg tcaggggccg catcccacgc cgggtgggcc
    11701 cggcccgcgt gccccggtcc gccgccgttg gcgcattcgg gtggcttcgc gcgcatcccg
    11761 cgtacgggga aacggggcgg gagacctctc agagagccgc gacaggcgca cttcgagaaa
    11821 ggaaaccggc atgctgggag acaaactgaa ccctggggaa ctcgtccgtt tcggtgaagg
    11881 gcgcggtgaa taccacctga cctcccctgc ggccaccgcc ctccaagagg ccgggatcgt
    11941 cctgaaggcg ctgtcgcccg gcgaagcgca cagcaacggg aacgggggag tgtcgctgcc
    12001 catcaccggc ggggacatcg acccggatct ctcccgggga aagcttcact gcgagggcgg
    12061 attcgacttc acccacagcg acggccggag gctggagatc cgcgaccact gggcggacgc
    12121 ggcgacctcg cgctactgcg ccaccgtcgc cgggcgcgaa gtgccctggc tcgccttccg
    12181 cctggacccg caggcgctgt cgctgacttc cggccggctc acggcgaaac tcccggtcac
    12241 gctgaccgat gagggagccg ccctgttcac ggaggtactg ggcgcctccc cggtctcccc
    12301 gggcgagcac cttttcgaca cggaaggtca ggtctcactg gcgacgatgc cgttgggcct
    12361 ctgacggagg cggtcctccg aggcagcggc gctcgctgtt ccgagtgaac cgacaagcga
    12421 gctgccggag gacgtcacga gcgggtgggg gcgctacgcg gcccatcgct ttcggtcccc
    12481 gcgatccgtt gccgtgcggg gccggttctc gttgctcaag gagacgaggc cgaccggtcg
    12541 ccgggcccca ctgggccgga tggccggtct gttcgtggtc ggccgccgtc ccgacggcag
    12601 cttccggacc cgcctgaccc gggacctctc ctgcacctgc ctgggcgcgg cccgccgctg
    12661 accgcggcgg ctcaccggga aacccggctc acctggacgt gaacacggaa acatcgcctt
    12721 cacgttcgag gcggcggcag gaaatacgcc ctgcctagcg tgccccgtgg ccggctgccg
    12781 gccgtcgcag ccaccgcacg cccaggagac cgcatgagca gtaccgagca acgatcgaag
    12841 gaacccgccg tccgcgaaga gactccgcac gccagggccg ggcacgcggc ccgggagacc
    12901 ttggaggact acaccctccg cttcgccccg cgcggctacc gccgctggac gccgatggtc
    12961 gtggcgacca cggcgatggg cgggatcgcg tacctggccg acttctcgat cggcgccggc
    13021 atcggcctca cgcacggcac cgggaacgcc ctcgccgcga tcctcgtcgc cgccgtggtc
    13081 atcttcgtca ccggctttcc tctcgcctac tacggggcgc gctacaacat cgacctggac
    13141 ctgatcaccc gcggctccgg cttcggctac tacggttcgg tcctgaccag cgtcatcttc
    13201 gccagcttca ccttcgtctt cttcgccctc gaaggatcga tcatggcgca ggggctgaag
    13261 ctgggcctgg ggctgccgct gtggctcggt tatctggtct cgacgttcat ggtgatcccc
    13321 ctggtcgtct acgggatgaa ggcgctcagc aggcttcagg tgtggacgac acccgtctgg
    13381 ttgctgctga tggtgggacc gctggtctac ctggtggcca ccgacccggg caccgtggac
    13441 cgctggttgt cctacgcggg caccgacggc cagggagggg tgaacaccgc ctcggtgctg
    13501 ctgggctccg gcgtctgcct gtcactgatc gcgcagatcg gcgaacagat cgactacctg
    13561 cgtttcatgc ctccccgtac cgacgcgaac cgccgcgcct ggtggacggc ggtcgtggtg
    13621 gccggtcccg gctgggtcgt gctcggtgcg ctgaaacagg cgacaggagt cttcctcgcc
    13681 gtctacgtca tcgcctcggt ggggccggcg gccgcgaccg agcccgttca gcagttcaag
    13741 gccgccttcg acgcgatgat gccctcgtgg ctggtcgttc cgctggccgt ggtcctggtc
    13801 gtgatcagcc agatcaagat caacgtgacg aacgcctact ccggctcact ggcctggacc
    13861 aactccttca cccggctgac cgggcgctac ccgggccgca tggtgttcgt cctgctcaac
    13921 ctggccttcg cgctggcgct gatggaggcc gacatgttca gcttcctcaa ccgcgtcctg
    13981 agcttctact ccaactgcgc catcgcctgg gtcgtcaccg tggccacgga catcatcgtg
    14041 aacaagtacc tgctgaaact ctccccgcac gcccccgagt tccggcgcgg catgctgtac
    14101 gccgtcaacc ccgtgggcac ggtcgccttc gtcgccgcct ccggcctgtc gatcgccctg
    14161 tacttccacg ccctcggcga cacgctccag ccctactcgc cggtcgcggc ggcactgatc
    14221 gccttcgtcc tcaccccgct gatggccgta ctgaccaagg ggcgctacta cctgcgccgc
    14281 accacggacg ggatcgacga acccctgctc gacgccgacg gcaacccgag cgccacgctc
    14341 tacgagtgcc acgtgtgccg gcaggagttc gagcgcccgg acgtggccgc ctgccgcacc
    14401 cacgacgccg tggtctgctc cctgtgcctg agcaccgaca ggatcggcga ccacgtcctc
    14461 cccgcgggcg gatgaggaac gtcgtgaccg tcggaccggc gtcagccggc ggcgggttcg
    14521 atgccccagg cggcggcccg gccggcggcg gccgcgcggt tggggacgcc gagcttggtg
    14581 aggatgtgct cgatgtgggt ccccacggtg cgcggtgtga cgtacagccg ctcggctatc
    14641 tcccggttgg tgcggccggc tgtcagttcg gccagcacct ggagctcacg tggtgagagc
    14701 ccgccgggcc gccctgtgcc agggtgccgc gcgtccgcgg cggggccggc cgtgacggcc
    14761 tcctcgggcc gcggacccgc gtgacgggcc acggccgcgg cgagggcctc ggtgagcagg
    14821 gtgaccacgg cgcgcgccgg atcgggcgtg cgccgcggcc ggcgggtgct gacgttcagc
    14881 atgccgacgt accggccgtc ggcggcgaac aggcactggg ccacgccgtc ctcgatgccg
    14941 aggggagaca gcacgtcctg gaagcccggg gaggccgcca ggagccgcgg ggggacgtcc
    15001 ctgagccaga ggccgccccg ggccggactg cggagcacgg ggaacaccgg gtcgtggtgg
    15061 aggcgggtct cgatgtaggc cgtggcgtcg tccgggtagc tcccggccag cgtggtgtgg
    15121 cgccggcgca gcggatccca ccgggacagg gaggcgtggt cgtactccat cacctccgac
    15181 agcgccgcca ggaccgtgtc gacgccggtc gcgccgctcg tggcgctcct ggcggcctcg
    15241 cggacgtgga cggccgcgtc caggatgtcc gccgtgctcc gctccgttgc cattccccaa
    15301 ggatgatcat gtggctggaa tacgtcaatc gcggagggtg tcgtgcacga cccgcccgtc
    15361 catgacggtg aggacgacgg gcatctccgg gatgtcgtgg gggtcggcgg tgagcaggtc
    15421 cccgtcgagc acgcagaggt ccgcgacctt gcccggctca agggagccct tccagtcgtc
    15481 ggcgaagtcc tgccacgccg cgtcgatcgt gtacgtacgg atcgcctcgg cgagcccgat
    15541 gcgctgcccg gggccgctga cccggccggt ggccttcgac tcgcgcagca tcatggtggc
    15601 gacgccctgg cgccagtccg ggtacgtgac gggggcgtcg gagccgctcg cgacccgtac
    15661 gccggcgtcg atggcatcgc ggtagggcca tgcgtacgcg gcccgttcgg cgccgacgaa
    15721 atcctcctcc atgtcggcga cggtccactt gatggtgggg ttcatgttga cgccgaagcc
    15781 gtgcgcggcc agcaccttca tgctgtacgc ggtgaggaag tcgccgtgga tgacgtagtg
    15841 gcgggcgtcg ggccgcgggt gctcggccac ggcggcggcg aaggcgtccg cgacggtgtc
    15901 gcaggcccgg tcgccggtga cgtggacgcc cagctggtac ccggcggcgt gggcgtgccg
    15961 gatgacggcc ccgatctcgg cggcccgctc ggtgtcgctc ccgccgccga cgcacaggga
    16021 gccgcagccg ccgccgacgt acggctcgtg catccaggcc gtcttgttgg ggaccacgcc
    16081 gtcggcgaag accttgaccc cgtggatcgc gaggcggcgc ggatcggcgt cgccggacac
    16141 gctgagagcg tcgagggtgc gggcgaactc ctcggcggtg ctcgtcatgc cggtgggcag
    16201 cagcaggacg ccgacgcgtg cggtcagctc gccctcggcc agcagctcgc ggtagacgtc
    16261 gagggtctcc gtgcccagcg tgccccgggt gatgccggcg ccgccggggc cgagcccggg
    16321 ctcggtgtag ctggtcacgc cgagccgggc gagcgtggcg agggccgacc tgatcgcgtc
    16381 ggcccgttcc tgccggctga gcggcggcag cgcgttctgg acgagggcct gggccccctc
    16441 gtggagcagc ccggtcggct ccccggcctc gtccgcgacg atggctccgc cgggcggcgc
    16501 gacggtgtgc cggtcgatcc cgatgagctc cagcgccttg gagttgaccc aggtggcgtg
    16561 cccggagaag gagtacagga cgacggggtg gtccgggctc acggcgtcga gatcgcgccg
    16621 cgagggcagc cgcgaaggtt cggagacgca ctcgtcgagg tagccggtgt cccagccgtg
    16681 ccccgtgatc cactgcccgc cgggcagccg cccggcggcc tcccgcaccg cctcggccac
    16741 gtccgcgagg gaggacacgg cgggatggcc gaggtcgagg gagagcggcg gcgtcgccat
    16801 gccgaaggcg cacccgtgca gatgggaatc gttgataccg ggaagcagcg tcgctccccg
    16861 caggtcgacg acgcgggtgc cgggcccgac gagcggtgcg acgtcgtccc gcccaccgac
    16921 ggcactgatg accccaccgg tcaccgccag ggccgaggcg agggagaacc ccgcatcgac
    16981 cgtgaccacc cgcccgccga gaaacaccag atccgcgtac gtgcccatag aaggtccttt
    17041 cggaagcggg cggcaccacg gccgcccgcg agcgatctcc cgaggactat gaccgcgctt
    17101 ttgcctcgcg cacatcggtc atgtcaccga tacgcgcgtt tgtgggggcg ggctgacggc
    17161 tcgtgcgcgc atcgtgcacc gatccgtcgg acacactggt gccgtgacca caccggtccg
    17221 ctggcgcccg gcgaccgacg gccggtcggc ggagcggccg ggtacagtca cccgatgctg
    17281 cgtatcgact tccccatcgc caccacccgg ctgacactcc gtccgttccg gcccgaggac
    17341 gccgaggacg tcggcgacta ccaaggccgg cccgacgtcg cccgattcat gcggtgggag
    17401 ccgcgcggag cggaggacgt ccgggtggcg gtggagcaga tgacccggga gaccgggctg
    17461 gtctcggacg gggactgcct cagcctggcg gtcgtcgagc cgggcacggg gaaggtcgtc
    17521 ggacaggtcg aactcgtcct gctcagcgcg gaacaccgcc agggcgagct cggctatgtc
    17581 ttccaccccg ctcaccaggg caagggcttc gccaccgagg ccgcgtccgc cgtcctgcgc
    17641 ctgggcttcg aggaactggg gctgcaccgg gtgatcggcc gctgccacgc ggacaacacc
    17701 gcctccgccg gtctcctcga acggctgggc atgcgccggg aggcccgtct catcgggacg
    17761 gagttcttca agggggcatg gcgcgacgac ctggtgtacg ccatgctcca gcgggagtgg
    17821 caggcaccgg ccgcccggcg ggacacggca catgcccctg aagcaggcac cggcgcccgc
    17881 gcttgaccga ggccgggccg ggcggccgcg cgggtcggcc ttgagatccc tacccgcccc
    17941 gcgggtcacc gattcttgaa ctcctcgatg gccgccctgg ccgcatgctg catcgcgtcg
    18001 cttccggcgt gcccggagtc ctcgaagatg tggagccgcg cgtccggcca caccttcgcc
    18061 agctcccacg ccgtcggtac cgggctgccc atgtcgtgtc ggccgtggac cagtaccgcc
    18121 ggcttcaggc gcgagggttc agtggcccga tgcggtagag gatctcgtca tggtcgccgc
    18181 ccgggagctc ctccgcgagg aacagcggtt cggtgtggat gtcggcgtcg tatgcgttgg
    18241 cgaccatacg cagcagcatg gtgatcggct tgttctgctc ggagacgctg gtttcgacgt
    18301 atttcgcccc cgcggccagc tggaggtcga tcgcgttcgc gaggatgtcg attccgagcc
    18361 cagagatgcc gctgccgggc ttgaccgccg cctgccagat gaagaacgta tccggttcgt
    18421 cggggcggcg gtatccggtc atgaagccca cgatgtcgtc gcccgcggtg gccaccatgg
    18481 aggtcttggc gaagtcccgg aaccagagcg tgtagtggta ggaactgttg tcgtccagca
    18541 tcggctcgtc gacgaccatc cgccacacgg ggacggcgtc cttcggggta ggtgtgcggt
    18601 agcggacttc ggtcttctcc gacagtgagc cggtcatcgt tcttcccttc gcgtcaggcg
    18661 gatcagagcg tcaatcggtg gggtccgggg cggccggcga tcgcgcgcac atcggtgatc
    18721 cggtgtgtgc tcgcgatcgc ggcggcgtgc ccttccacga acacgtccag gaggtggacc
    18781 tcggacgaag gccagtcctc ggcgggactc ccgtggggaa gggccaggtc accccgcacc
    18841 ccgatacggt ccagccgggc cgccaggccg tgtcccgtga gcttgacggt ggcctctttc
    18901 ctggaccaga gcctcgtgaa ggccccgggc agttcatgcg ggggcagctg ggacagggcc
    18961 acgcgttcgt ccggtgtcgt ggtgcgcgcg aggagaccct gcgggacgcc ggggcccgcg
    19021 atcgtttcga ggtcgatgcc cacgagcccg tacgccacga ccccgaccag aacccggtgg
    19081 cgagtgtgcg cgaccgagta ctcgtacccg gctccgacga cgcgagggcg gccatggccg
    19141 gcgccgcagc gttcacaggt gcgctcgacg cgcacctggc ggggagggct gccggtgtac
    19201 cggcaggcga tcagacgctg agtcgctcgc gaggtgacga agagatctcg tcgcccgccc
    19261 tcgggaatcg cctcggcgcg ggccgcctcg tcgggtgcca gcagtccttc ccagccgggt
    19321 cgcgcgcgga cgggcaccga ccagaggtgg cactcgccgg cggcgggcag ggcgtcgacg
    19381 gcggacagct tcgctccctt cccggtacgg ttccgaattc gtcgtccgcg gccccggcag
    19441 gtcgctcgcg tgacccggtc gccggggccg cgagcgacga aggccgggat cagacctcgt
    19501 actcggttcc gacgccgtcg aagcggaggc ggtcctggat gaacacctcc tcgccgttct
    19561 tgtcgtagcc ggtcaagagg cctgcctcca tgaggcggat gacgatctgg gagctcagct
    19621 cctgctggtc ggcttcgctc agttcgcgga tgagctcctt gtagccgacc tcctccttga
    19681 ggaggcggct gaagatctgc cggtgcttct cctccagcgg ccacttgatc atgtcgcggc
    19741 cctcctcatt ggcgaggacc tgcttggact ccagcctgaa cgtctccgga tcgaccttgt
    19801 agtacggctt gagggccacc tccttaccgt tccactggag acgcttgatg cggttgagcc
    19861 gcttggtcag ctgactgatc cagcgcacgc gggcggggtt gagctcgtcg tcggtgaact
    19921 cgtcgctcag ctccatgcgc tggtggcgtc cgatgctcat catggtcgtc gcgcggtccc
    19981 ggaagtcggt caccgaccac gtgccgtcct tgctggaagc ggccaggcgt tcgaaccagc
    20041 gcttgcggtt cagccgcccg tcgtcggatt cactgatgcg ccgcctgacc cagaactccg
    20101 actccggttc ggtgaaggag gccagggtgt agaaggaggc gaggaactcg tggtattgct
    20161 cgtaggtctc acggtaggcg cggttgtacc aggcgtggac ctcctcggtc tcctcctccc
    20221 gcctggtgat ccggtcgatc gcggcggccg cggagacggc cgactgcgtg gccaggtgca
    20281 cgccctggga gaacagcggg tcggtgaagc aggccgagtc gccggagagg aagtagcggc
    20341 cgccggagta cacctcggag tcgtacgacc agtcgtggac cacccggacc tcgtcgacca
    20401 tctcggcgtc accgaggatc tccttggccc ggacggcctt ggcgagggac tcacggtaga
    20461 agcggtcggg gcccctctcc ttcacctcgc tcgacttcga gcggtcgacg accagtccga
    20521 cactgtagag gtcgcccttg agcgggatca tccacaccca gccgtcctcg aaggtgatgg
    20581 agtaagtcgt tccgttgaga tcgccctcga aggggtcggg gcagcggaag tacgaccaga
    20641 tcgcgaagct cttgtagaac tcgtcgtagc gccgcacttt gagcttccgg gccaggggcc
    20701 cgttggcgcc gccggcgtcg atcacgaagt cgcactccac ctgcctcgcg tcaccgccct
    20761 ggcccgcggt gagcgacacc tttccgggat ccgctatgtc gacatgggac accggcgtgt
    20821 tctcgtgcac ctcgatgccg cgctccttca cctcgtcgag gaggagctgg tcgaattcct
    20881 cacgcttgac ctggatggcg tggtcgaaga cccacggcga cgtcttcgga gtggtgaagg
    20941 agaaggtcca cggagcctcg tcctggcccc acaggaaagt ggccgagggc ttctcgacga
    21001 agccggcggc atcgatcctg tcctgaaggc cgagccggtc gaagatggac agcgaaccgg
    21061 ggaggaggga ttccccgatc cggtagcggg ggaagctgtc gcgctcgaag acgaccggtt
    21121 cgtggccgag cttgtgcagc gtgagggcgg cggtgcagcc ggcgggtccg gccccgatga
    21181 tggcgacggt cgatcggttc atgggcgttt ccttcacgac tggagggact tgatggactt
    21241 gacgcggctc ggggagaggt aggagaagcc gctcgcggcg ttctcgaaca tggtgatccc
    21301 cgcctggaag cggcatgcgt cgccgatggc gacctccggg gcgacggtgc agccgaggcc
    21361 gaagaagttc cggtccccga tctccacgct gttgccgccg tggaagttcg gggagaagaa
    21421 gttgcccgac ccgatgcggg agtggtgccc gaacgtgcac cggtaattga cgacgttgta
    21481 gcttccgagg acggtgttca cgccgacgta gttgtccggt ccgatgatgt tgcccacgcc
    21541 gtcgaccgcg gcggg
//
