LOCUS       NZ_CP021744            21143 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces albireticuli strain MDJK11 chromosome, complete genome.
ACCESSION   NZ_CP021744
VERSION     NZ_CP021744.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces albireticuli
  ORGANISM  Streptomyces albireticuli
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8144417)
  AUTHORS   Wang,Y., Du,B., Ding,Y., Liu,H., Hou,Q., Liu,K., Yao,L. and Wang,C.
  TITLE     Streptomyces albireticuli Genome sequencing and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8144417)
  AUTHORS   Wang,Y., Du,B., Ding,Y., Liu,H., Hou,Q., Liu,K., Yao,L. and Wang,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2017) Department of Mcrobiology, Shandong
            Agricultural University, No.61 Daizong Street, Taian, Shandong
            271018, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 2.3
            Expected Final Version            :: yes
            Genome Coverage                   :: 88.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 07:12:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,975
            CDSs (total)                      :: 6,876
            Genes (coding)                    :: 6,711
            CDSs (with protein)               :: 6,711
            Genes (RNA)                       :: 99
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 165
            CDSs (without protein)            :: 165
            Pseudo Genes (ambiguous residues) :: 0 of 165
            Pseudo Genes (frameshifted)       :: 74 of 165
            Pseudo Genes (incomplete)         :: 97 of 165
            Pseudo Genes (internal stop)      :: 5 of 165
            Pseudo Genes (multiple problems)  :: 9 of 165
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:17:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6500624
            Orig. end                         :: 6521767
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP021744.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21143
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="29"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21143
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21143
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11143](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11143
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            425..1249
                     /locus_tag="SMD11_RS28265"
                     /old_locus_tag="SMD11_5731"
     CDS             425..1249
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058589.1"
                     /locus_tag="SMD11_RS28265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5731"
                     /product="HipA family kinase"
                     /protein_id="WP_087929129.1"
                     /transl_table=11
                     /translation="MLPEVTATRYVTPLREGGSLPGIVEADDLGTYVMKFTGAGQGRKT
                     LVAEVICGQLGRALGLRVPDLAKIQLDPVIGRGEPDQEVQGLLKASGGLNLAMDFLPGA
                     LGFDPLAFETDAAEAGRVVWFDALINNVDRSWRNPNLLVWHGQLWLIDHGATMIWHHNW
                     PSATAAAGKAYDASDHVLASFAPDVAGAAAALAPKVTEELLTEVAADVPDEWLVDEPGF
                     DSPDALRRAYVEVLLERAATIGDRVVLGERSKDKPSQAPEWVRVRLDGKAGK"
     gene            1246..1641
                     /locus_tag="SMD11_RS28270"
                     /old_locus_tag="SMD11_5732"
     CDS             1246..1641
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014181330.1"
                     /locus_tag="SMD11_RS28270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5732"
                     /product="DUF3037 domain-containing protein"
                     /protein_id="WP_087929130.1"
                     /transl_table=11
                     /translation="MTGRHNGRDVFEYALLRVVPRVERGEQINAGVVVYCQAKSYVAAR
                     VHLDEARLLALDPTADVAGVRAALGAVEGVCLGGERAGQAAEDAPGRRFRWLIAPRSTV
                     VQPGPVHTGLTADPEGEPERLLDLLVR"
     gene            1815..2576
                     /gene="fabG"
                     /locus_tag="SMD11_RS28275"
                     /old_locus_tag="SMD11_5733"
     CDS             1815..2576
                     /EC_number="1.1.1.100"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-168). E-value: 4.3e-21. Score:
                     67.6. Matches aSDomain:
                     nrpspksdomains_SMD11_RS28275_PKS_KR.1"
                     /codon_start=1
                     /gene="fabG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262869.1"
                     /locus_tag="SMD11_RS28275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5733"
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="WP_087929131.1"
                     /sec_met_domain="adh_short (E-value: 4.1e-37, bitscore:
                     126.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTEQRVAVVTGAARGIGAATAVRLAGEGRAVAVLDLDEAACAG
                     TVEKITAAGGTALAVGCDVSDSAQVEAAVARIADGLGAPVILVNNAGVLRDNLLFKMSD
                     DDWDTVLSVHLRGAFLMSRACQKHMVDAGFGRIVNLSSSSALGNRGQANYAAAKAGMQG
                     LTKTLAKELGKFGVTANSVAPGFIATDMTAATADRVGMGFEDFKAAAASQIPVQRVGEP
                     EDIANAVAFFTGEQAGFVSGQVLYVAGGPLN"
     aSDomain        1836..2318
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SMD11_RS28275_PKS_KR.1"
                     /evalue="4.30E-21"
                     /label="SMD11_RS28275_PKS_KR.1"
                     /locus_tag="SMD11_RS28275"
                     /protein_end="168"
                     /protein_start="7"
                     /score="67.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAVVTGAARGIGAATAVRLAGEGRAVAVLDLDEAACAGTVEKITA
                     AGGTALAVGCDVSDSAQVEAAVARIADGLGAPVILVNNAGVLRDNLLFKMSDDDWDTVL
                     SVHLRGAFLMSRACQKHMVDAGFGRIVNLSSSSALGNRGQANYAAAKAGMQGLTKTL"
     CDS_motif       1842..1907
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SMD11_RS28275_0001"
                     /evalue="8.70E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="SMD11_RS28275"
                     /protein_end="31"
                     /protein_start="9"
                     /score="8.8"
                     /tool="antismash"
                     /translation="VVTGAARGIGAATAVRLAGEGR"
     gene            2594..3346
                     /locus_tag="SMD11_RS28280"
                     /old_locus_tag="SMD11_5734"
     CDS             2594..3346
                     /NRPS_PKS="Domain: PKS_KR (8-172). E-value: 4.4e-09. Score:
                     28.4. Matches aSDomain:
                     nrpspksdomains_SMD11_RS28280_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010062246.1"
                     /locus_tag="SMD11_RS28280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5734"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_087929132.1"
                     /sec_met_domain="adh_short_C2 (E-value: 1.4e-31, bitscore:
                     108.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPDSGKVALVTGASRGIGYGIAEALVARGDRVVITGRDEESLK
                     RAAEALGPDRVLGVPGKAHDEAHQAAAVERAMDAFGRIDYLVNNAGTNPVFGPIAELDL
                     AVARKVFETNVISALGFAQQTWRAWQKENGGAIVNIASVAGLGASPFVGAYGISKAAMV
                     NLSLQLAHEMAPGVRVNSIAPAVVKTKFAAALYEGREAEVVASYPLGRLGVPEDIGGAA
                     AFLLSAAAAWITGQTLVVDGGIFLNAGF"
     aSDomain        2618..3109
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SMD11_RS28280_PKS_KR.1"
                     /evalue="4.40E-09"
                     /label="SMD11_RS28280_PKS_KR.1"
                     /locus_tag="SMD11_RS28280"
                     /protein_end="172"
                     /protein_start="8"
                     /score="28.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VALVTGASRGIGYGIAEALVARGDRVVITGRDEESLKRAAEALGP
                     DRVLGVPGKAHDEAHQAAAVERAMDAFGRIDYLVNNAGTNPVFGPIAELDLAVARKVFE
                     TNVISALGFAQQTWRAWQKENGGAIVNIASVAGLGASPFVGAYGISKAAMVNLSLQLAH
                     E"
     CDS_motif       2624..2710
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SMD11_RS28280_0001"
                     /evalue="1.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="SMD11_RS28280"
                     /protein_end="39"
                     /protein_start="10"
                     /score="17.4"
                     /tool="antismash"
                     /translation="LVTGASRGIGYGIAEALVARGDRVVITGR"
     misc_feature    3383..3398
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.35"
                     /tool="antismash"
     gene            3424..4110
                     /locus_tag="SMD11_RS28285"
                     /old_locus_tag="SMD11_5735"
     CDS             3424..4110
                     /EC_number="3.2.2.27"
                     /GO_function="GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004947262.1"
                     /locus_tag="SMD11_RS28285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5735"
                     /product="uracil-DNA glycosylase"
                     /protein_id="WP_087929133.1"
                     /transl_table=11
                     /translation="MTVTDTLPESWRGVLGEELEKPYFKELTDFVEEERANAPVYPPRG
                     EVFAALEATPYERVKVLVLGQDPYHGAGQGHGLCFSVRPGVKTPPSLRNIYKEMREELG
                     YDVPDNGYLQPWAEQGVLLLNAVLTVRGGEPNSHKGKGWEKFTDAVIRAVASRPDPAVF
                     VLWGNYAQKKLPLIDETRHTVVKGAHPSPLSAKKFFGSRPFTQINEAVAAQGHEAIDWR
                     IPDLAV"
     gene            complement(4162..4938)
                     /locus_tag="SMD11_RS28290"
                     /old_locus_tag="SMD11_5736"
     CDS             complement(4162..4938)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS28290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_5736"
                     /product="hypothetical protein"
                     /protein_id="WP_159395366.1"
                     /transl_table=11
                     /translation="MHRVPAAAALTVVAMMATTGCVSVSPHTAAHAPAGSSRWSGSGPR
                     TGPGPAREALATTGPDGPGAGPRTGRGGDPDRLGGAPTFWDPSDLSHPGAPRDLERFWN
                     PADPSAPSVFTDPSSPSGPSGPSGHADRPARSGPSGPSGPAGSSGPADRSPGRSAHSSS
                     PSDSGSAPGSSGPSRDAGPQAASPERSAPRQDTPAPQHHSDPPASGHASEPRHEAPAPA
                     PAPAKGGGNVCAMGRDYGRWQQGGDANRICGQVYGH"
     gene            complement(5243..5872)
                     /locus_tag="SMD11_RS28295"
                     /old_locus_tag="SMD11_5737"
     CDS             complement(5243..5872)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009713164.1"
                     /locus_tag="SMD11_RS28295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5737"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_107421980.1"
                     /transl_table=11
                     /translation="MSVEKEPAQYPGKPLVRLPAGAARGRLIADTALDLLAERGMRGLT
                     HRAVDEAAGLPTGSTSNQARTRLALLEAAVRRLAVREGEVLALKELPDPADGPEALADA
                     IALALHRTLTGRRELLIARYELALEASRRPELRAIYDTEGRAFREPLVALLTAAGSKAP
                     ERHALSVLAWCEGLMFSCAAGSYHAEVPGVEGLRVSARELLRGVLG"
     gene            5950..7181
                     /locus_tag="SMD11_RS28300"
                     /old_locus_tag="SMD11_5738"
                     /pseudo=""
     CDS             5950..7181
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016827205.1"
                     /locus_tag="SMD11_RS28300"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5738"
                     /product="FAD-dependent monooxygenase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRELRAVVIGGGVGGLTAAAALHHRGWDVTVLERAASLEPVGAGI
                     ALAANAQRALDTFGAGDAVRALSVPQVDGGLRRPGGYWLSRTDNAAAARRFGGPVVVAH
                     RADVIALLASRLPEGAVRTGVRGELADPGGPDRPARVTTPGGVLEAELVVGADGIHSAV
                     RAALFPGHPAPRYTGFTTWRFVVPAAAAPQGGTTAHETWGPGRLWGTVPCSTAASTPTP
                     RPPRPPARSPRAANSPSCAASSATGTTPCRSSSPPPTPPPCCATTSTAPPTRCPPTTTA
                     GSPSSATPPTP"
     gene            7178..8083
                     /locus_tag="SMD11_RS28305"
                     /old_locus_tag="SMD11_5740"
     CDS             7178..8083
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005320247.1"
                     /locus_tag="SMD11_RS28305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5740"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_087929135.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 2e-14, bitscore:
                     52.9, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGCIGLGDIAQKAYLPVLTTQPGLEPHLHTRTPETLHRVADTY
                     RVPDAHRHTDLDSLLAAGLDAAFVHAATAAHPEIVTRLLEADVPVYVDKPLAYDLAGSA
                     RLVRLARERRVSLAVGFNRRHAPGYAQCLDHPRDLILMQKNRVGLAEDPRTLVFDDFIH
                     VVDTLRFLAPGPVEHVDVRARVRDGLMHHVVLQLSGDGFTAIGTMNRMSGSTEEILEVS
                     GQDTKRQVVNLAEIVDHKGQPSVRRRGDWVPVARQRGIEQVVGVFLDAVRAGEVLDAED
                     ALRTHELAERVVNAALEQAS"
     gene            complement(8055..9614)
                     /gene="lnt"
                     /locus_tag="SMD11_RS28310"
                     /old_locus_tag="SMD11_5741"
     CDS             complement(8055..9614)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016410 - N-acyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006497 - protein lipidation [Evidence
                     IEA]"
                     /GO_process="GO:0042158 - lipoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lnt"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014181339.1"
                     /locus_tag="SMD11_RS28310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5741"
                     /product="apolipoprotein N-acyltransferase"
                     /protein_id="WP_087930776.1"
                     /transl_table=11
                     /translation="MASSVRRYGPLRAGPWRRGALAVVAGALPALCFPAPALWWLAYVA
                     LAPWLLLVRSAATGRRAALEGWLGGAGFLLAVHHWLLPSLHVFILVLAALLGLLWAPWG
                     LVVHRLLGGSPGAGRCAAALVVVPSAWLMVELVRSWEYLGGPWGLFGASQWQVPPALRL
                     ASLGGIWLVSFLLVALNTALATLICAPRARATGAVGALACAAVAAGGWLWAPQPRAAGN
                     VRIAVVQPGVVFGAHSPQRRFDREEELTRQLAGQRPDLVVWGESSVGEDLDRRPDLRKR
                     LAALSQETGADLLVNVDARRADRPGIFKSSVLIGPTGPTGDRYDKMRLVPFGEYVPARS
                     LLGWATSVGKAAGEDRRRGERPVVMRLPSGLRIGPLVCFESAFPDMSRKLARDGAGVLV
                     AQSATSTFQHSWAPRQHASLAALRAAETWRPVVHATLTGVSTVAGPRGETVGAPLGTER
                     SAAAVYEVPLARGTSPYVRTGDWAVLGSVTVLVCYAAAATARALRRRRSGGTVRKPAPE
                     RR"
     misc_feature    9712..9725
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.97"
                     /tool="antismash"
     misc_feature    9713..9726
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.95"
                     /tool="antismash"
     misc_feature    complement(9760..9772)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.22"
                     /tool="antismash"
     misc_feature    9920..9931
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            10001..11143
                     /locus_tag="SMD11_RS28315"
     CDS             10001..11143
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="SMD11_RS28315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_234366478.1"
                     /sec_met_domain="T1TS (E-value: 1.2e-70, bitscore: 237.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPFYCPIAPAVHPRVREIDDASVDWMLQQELDTSSHQRQRLIRCD
                     FGGLTARTMPYGQVRPLTVVAKLHSVLFSLDDALCDEAGATAHGLAHTTSRIMRVLEAP
                     TPAWPDDSPHAAALRAVRLELAEHATPGQLRHWTEGMRTYMSGLVWEAACRRDRALPSV
                     NDYAAMWMRAIGMAPSTALMDIAGGYELQDQDLDRPEIRAMTEMTWTLVAWDNDFYSRN
                     KEIQRAGDNLNLIDVLAQERDCTPARAQEEAMAMRDRVMTLFLRLREQLWPRSGVELRC
                     YLVALGQFVRGHLDWASACARYADPYGSGEPARWWKSAPADDSPEPLPLPAVAWWWDQL
                     ESTPYPRRSQRRNDLHHDVRDGVARPDGAGVTTGCSSRSG"
     misc_feature    10400..10402
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11032..12429)
                     /locus_tag="SMD11_RS28320"
                     /old_locus_tag="SMD11_5744"
     CDS             complement(11032..12429)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014181452.1"
                     /locus_tag="SMD11_RS28320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5744"
                     /product="cytochrome P450"
                     /protein_id="WP_234366479.1"
                     /transl_table=11
                     /translation="MAVPPPQCPAHGPGGVTRLYGPEAEADPMGLYERLREKHGQVAPV
                     LLHGDVPAWLVLGYRENLDVARTPSRFSRDSRLWREAREGRIAPDHPLTPITTWQPICV
                     FADGQQHERWRGAVNDGIARFDKRGIRRHVTRFANQLVDRFCEAGRADLVHQFAEHLPM
                     MAMTQLLGMPEAYDTRLVNAARDMIKGTETAVASNEFVQETLRKLVARKRVEPGSDFTS
                     WLLEHPSGLTDDEVQQHLRLVLIAAYETTANLIANTLKMVFTDVRFRASLAGGHMTLPD
                     AVEQVLWDEPPFITILGRWATQDTELAGQPIKEGDALVLGLAAANMDTVVRPDPDLPIH
                     GNRSHLAFSGGAHECPGQDVGRAIADTGIDALLLRLPDLTLAVEESELVYASALMSRHL
                     TALPVKFAAQPPLPPEPAEDRAPEGPASSVQPERLEQPVVTPAPSGRATPSRTSWWRSL
                     RRWLRRG"
     gene            complement(12462..13112)
                     /locus_tag="SMD11_RS28325"
                     /old_locus_tag="SMD11_5745"
     CDS             complement(12462..13112)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004954305.1"
                     /locus_tag="SMD11_RS28325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5745"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_087929138.1"
                     /transl_table=11
                     /translation="MDYRSSDPYASPYGPDTPAGPRREDVLPASATAAVKVVIVGGFGV
                     GKTTLVGAVSEIRPLTTEETMTQAGVGVDDLAGVEHKTETTVAMDFGRISINEQLVLYL
                     FGTPGQERFWFLWNGLFEGALGAVVLLDTRRLEVSYDVIGRLEERGVPFVVGVNRFPGS
                     PTYPMAELRAAMDLEDSVPMVDCDARDRGSCRDTLLTLMRYLYTLTTASPEPQ"
     gene            complement(13093..13461)
                     /locus_tag="SMD11_RS28330"
                     /old_locus_tag="SMD11_5746"
     CDS             complement(13093..13461)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004954302.1"
                     /locus_tag="SMD11_RS28330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5746"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_087929139.1"
                     /transl_table=11
                     /translation="MNGAGPDPATAPGSPDRLYILTGGQDRAEQRRTELDLVTLIVSRT
                     ESEAGLQPEHAAIVRMCHYPLSVAEISAYLELPVSTLTQLLTELLAGRQVEARPPVPAA
                     ALPDVRLLEAVMNGLQKL"
     gene            complement(13458..13871)
                     /locus_tag="SMD11_RS28335"
                     /old_locus_tag="SMD11_5747"
     CDS             complement(13458..13871)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056718.1"
                     /locus_tag="SMD11_RS28335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5747"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_087929140.1"
                     /transl_table=11
                     /translation="MTQPRFNMDWMLKDLATGVPQTRHVIVLSSDGLRMAQHGTDPDVA
                     DRLAAACAGLQSLSAAIAAEFPNPRGDGQMRLVVIEVDGGFFYLMAAGAGAYLAVLADD
                     DVDAELMGLRMRDLVARIGSHLTSPPRVGGPVT"
     gene            complement(13876..15429)
                     /locus_tag="SMD11_RS28340"
                     /old_locus_tag="SMD11_5748"
     CDS             complement(13876..15429)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056717.1"
                     /locus_tag="SMD11_RS28340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5748"
                     /product="ATP-binding protein"
                     /protein_id="WP_234366193.1"
                     /transl_table=11
                     /translation="MVGTGSSDRRRPVSALIWLISPLVLAVCTGTAVVAVTPEARVPVG
                     WCGSSATVAVALAASEAARRGRVITTLRRRCAEQETALRYRLDEHEAETFRLARELLPR
                     AVRLLKRGEPTEVILRHTLPTHDLEPGYAAAHRSVLKSVIEAVQAEESMRDSAQRAFVN
                     IARRVQAIVHQQAYDIREMEHKHGNDPDVFGDLLHLDHGNALTGRLADSIAVLGGSRPG
                     RQWKNEIPLYNVLRGAMSRILEYRRVDLHSVADVAVVGPAVEPVIHALAELLDNATRYS
                     PPQTRVHLTAVDIQSGIAVEIEDAGVGLTDEARRRTDRVLSKESELDLDDLGEAPRLGL
                     AVVARLARSYNFLVSLRPSAYGGVRAVLVIPMDLITASKHPGGDIARAPKLPPFKSKRR
                     PGQRIPAPGPETPPPMMEHPIPPPLGDSGLPQRRRRRGPAPLPFGRAAAAQREREREQA
                     MRTRPSVPVQPGPERDSLPEQPPKQPGMWLAAFTRGINGELPEPDPDRPNSDLSSDKEE
                     "
     misc_feature    complement(15726..15740)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.77"
                     /tool="antismash"
     misc_feature    complement(15728..15741)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.55"
                     /tool="antismash"
     misc_feature    15730..15748
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.68"
                     /tool="antismash"
     gene            15966..18668
                     /locus_tag="SMD11_RS28345"
                     /old_locus_tag="SMD11_5749"
     CDS             15966..18668
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004954293.1"
                     /locus_tag="SMD11_RS28345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5749"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_087929141.1"
                     /transl_table=11
                     /translation="MSGPQREQNAAAALFERELELETAEQAVHRLCGHVSEGRSRLGGL
                     LLYSGEAGLGKTSLLSELRRIATETERCTVLFARGSESSRSVPFNVVRQLLQPALAPMT
                     TAARQDLLSGWYDIAGPALGISPPSGPQDPQGVRDGLDWLVTQLAMKGDPVVVIIDDVH
                     WSDAESLAWLTSYAVRLREMPLLVALSYRPHELPDHTPAFRDLVEGRSVRPVELRALTP
                     DAVAGLVHSAFDGKADAPFCREVWAVTGGNPYEAVELIAKARERDLKPLEESAALLREL
                     GAAARGSGLVARLDSLGNAVTRFAFAAAVLGTEISPTLAANLAGMGPAQGADCADKLRK
                     ARILTGVHQLEFVHPLIATAVYSAIPAATRTAMHGQAAWAVSEAGQGAAVASRHLLEVH
                     PDHDPELVEQLRVASREHLAVGAPDAARRCLERALREPPPEEERASVLYELACSTLLTS
                     PSTTINHLKSALALPHLTEELRVDATYRLSQVYAHNNQLKEAAEVLSVQAARTPPGAGR
                     MRLQAAHYLWKGIQSEEVDAPARSRRISELADHLRGRDDAERALLAIRAFDGVIRGEDA
                     VQVLDRIERALVDGRLAHGMSWTNTEWGFELPSIVGISFLYTDRLDRAKELFEEAIRAF
                     EISGWSGIHLAFAHDFLGYAYRRLGELDKAEKLLREGLRLAYRLGPGLPIQWDGTCMLI
                     DTLLARGDVAEAQVVAEENGFRPPYTPAVVLPDAMCLAGRLMLAQGRRKEAVAELEAAG
                     RRLEERGRHNTVWAPWALDLAVAVAPDDPERARTLSGQAVRNAARFGTDSALGEALRMA
                     AKVAEPEDALKMLDQSVGHLRKSPCKYEFAAALVDHGVALNGAGRTAEAEERLREGREV
                     AEFCGAHGLVRTVRSLLPEAVCGEAEPAG"
     gene            complement(18696..19688)
                     /locus_tag="SMD11_RS28350"
                     /old_locus_tag="SMD11_5750"
     CDS             complement(18696..19688)
                     /GO_function="GO:0045027 - DNA end binding [Evidence IEA]"
                     /GO_process="GO:0006303 - double-strand break repair via
                     nonhomologous end joining [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008738109.1"
                     /locus_tag="SMD11_RS28350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5750"
                     /product="Ku protein"
                     /protein_id="WP_234366194.1"
                     /transl_table=11
                     /translation="MWKGAIGFGLVSVPVRLYAATQEHGVRLHQVHDKDGGRIHLKRVC
                     DVCGEQIDYEHIAKGFEDDEGHTAVVTQDELAGLPLPSKKLIDVLAFVDSDRIDPLQLA
                     SSYYLAPESAAANKPYVLLRETLKQTDRVAVTKIALRTRESLALLRVHGDLLTLHTMYW
                     PDEVRDSGDLAPPASVTVRPQELKMATSLMDTLSEDFDLAEQEDEYEVALRELIDAHLS
                     DRPVPRKETAPAPDNVIDLMAALQASIDSAGKKPSEPAAGRKAPAAKAARGTGKKTAAP
                     KKSAAARKTSSSSSTAKNSSSTAKKTTARSTTAKSTKKTAAKKTGRRAS"
     gene            19730..20632
                     /gene="ligD"
                     /locus_tag="SMD11_RS28355"
                     /old_locus_tag="SMD11_5751"
     CDS             19730..20632
                     /EC_number="6.5.1.1"
                     /codon_start=1
                     /gene="ligD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004954288.1"
                     /locus_tag="SMD11_RS28355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_5751"
                     /product="non-homologous end-joining DNA ligase"
                     /protein_id="WP_087929143.1"
                     /transl_table=11
                     /translation="MPASSDRQAVEIEGHRLSLSHLDRVLFPASGHTKAQVLHYYARVA
                     GVLLPHATGRPASFVRAPEGLTGQSWVAKNPPGGVPGWVSVVPVEHREGVTEQVVIDSA
                     AALIAMANLGAYEVHVPQWTAAAGPDAHDRLVLDLDPGPGADLVLCCRVAQRLRQLLDD
                     DGLTAHAVVSGSKGLHLYAALCPTPGRAASAYAKELAGRMQGEHPGLVVASMARAARRG
                     KVFIDWSQNASAKTTAAPYTVRLRDRPGVAAPVGWDEIAACADPGELAFTPEEVLDRVA
                     AHGDLLAPLTGDDTRRPLP"
ORIGIN
        1 tggtcgtccg gcggctgcac ggcctctcgc cgctcgccgg caccggcctg gacgccctgc
       61 tgcgcaacct cggctgccgc acgctcgtcg tcaccggggt ctccgccaac gtggctgtcc
      121 ccaacgccgt cttcgacgcc gtgaacctcg gctacacggc cgtcgtcccc gccgacgcca
      181 tcgccggggt gcccgccgaa tacaccgagg cgatgatccg ccacaccctc gccctcgtcg
      241 ccaccatcac cacggccgag gccgtgctgc gcgactggcg gcgcccgcgc cgggcccgct
      301 gaacccgcga cacccgcacg gccgggcccg cgacccggcc gggcggccgc tccacccgga
      361 cggccgcgcc caccccgccg cgcccggtgc cgggggcccc ggcccaccgc agtagcctgg
      421 ggcaatgctc cccgaagtca ccgccacccg gtatgtcacg cccttgcgtg agggtggctc
      481 gctccccggc atcgtcgagg ccgacgatct cggcacgtac gtcatgaagt tcaccggcgc
      541 cgggcagggc cgcaagaccc tcgtcgccga ggtcatctgc ggacagctcg gccgggccct
      601 gggcctgcgc gtcccggacc tcgccaagat ccagctcgac ccggtcatcg gccgcggcga
      661 gccggaccag gaggtgcagg ggctcctcaa ggccagcggc gggctcaacc tcgccatgga
      721 cttcctgccc ggcgcgctcg gcttcgaccc cctggccttc gagaccgacg cggccgaggc
      781 cggccgggtc gtctggttcg acgcgctgat caacaacgtc gaccggtcct ggcgcaaccc
      841 caatctcctg gtgtggcacg gacagctgtg gctcatcgac cacggcgcga cgatgatctg
      901 gcaccacaac tggccgtccg ccaccgccgc ggccggcaag gcctacgacg cctccgacca
      961 cgtcctggcc tccttcgcgc cggacgtcgc cggcgcggcg gccgccctcg ccccgaaggt
     1021 caccgaggag ctgctgaccg aggtcgccgc cgacgtgccc gacgagtggc tcgtggacga
     1081 accgggcttc gacagcccgg acgcgctgcg ccgcgcctat gtcgaggtgc tgctggagcg
     1141 cgccgccacc atcggcgacc gcgtcgtcct cggcgaacga agcaaggaca aaccctcgca
     1201 ggcgccggag tgggtgcgtg tcaggctcga cggaaaggcc ggcaagtgac cgggcgccac
     1261 aacggacgcg acgtcttcga atacgccctg ctgcgcgtgg tcccgcgcgt ggagcggggt
     1321 gagcagatca atgccggggt cgtcgtctac tgccaggcga agtcctacgt ggccgcccgc
     1381 gtccacctgg acgaggcgcg gctgctggcc ctcgacccga ccgcggacgt cgcgggcgta
     1441 cgggccgcgc tgggcgccgt ggaaggcgtc tgcctcggcg gggagcgggc cgggcaggcc
     1501 gccgaggacg ccccggggcg ccgcttccga tggctgatcg cgccgcgctc cacggtcgtc
     1561 cagcccggcc cggtgcacac cgggctgacc gcggaccccg agggcgaacc ggagcgcctc
     1621 ctcgacctgc tggtgcggtg agggtgccgg gccgcgccag ggggcgcggc ccgaggcgtt
     1681 gacagcgggt ggcggggctt ctagcgtctg atccactagc tactaagcgg ttgctcacct
     1741 gctcggccgg ggtggcgccg ctggagccga gcccgacgtc gacgccgacg tctccgaggt
     1801 gaggagagcc ccgcatgtcc accaccgagc agcgcgtagc cgtcgtgacg ggcgcggccc
     1861 gtggcatcgg cgccgcgacc gccgtccgcc tggccgggga gggccgcgcg gtcgccgtcc
     1921 tcgacctcga cgaggcggcc tgcgcgggca ccgtggagaa gatcacggcg gcgggcggca
     1981 cggccctcgc cgtcggctgc gacgtctcgg actcggccca ggtcgaggcc gccgtcgccc
     2041 ggatcgcgga cgggctgggc gcccccgtca tcctcgtcaa caacgccggg gtgctccggg
     2101 acaacctgct gttcaagatg agcgacgacg actgggacac cgtcctgagc gtgcacctgc
     2161 ggggcgcgtt cctgatgtcg cgggcctgcc agaagcacat ggtcgacgcg ggcttcggcc
     2221 ggatcgtcaa cctctccagc agctccgccc tcggcaaccg gggccaggcc aactacgccg
     2281 ccgccaaggc cggcatgcag ggcctcacca agaccctcgc caaggaactc ggcaagttcg
     2341 gcgtcaccgc caactccgtc gcccccggct tcatcgccac cgacatgacc gccgccaccg
     2401 ccgaccgcgt cggcatgggc ttcgaggact tcaaggccgc cgccgcgagc cagatcccgg
     2461 tccagcgcgt cggcgagccc gaggacatcg ccaacgccgt cgccttcttc accggcgagc
     2521 aggccggctt cgtctccggt caggtgctgt acgtggccgg cggaccgctc aactgacggg
     2581 gaggggaacg gacatgaccg caccggacag cgggaaggtc gccctcgtca cgggcgccag
     2641 ccgcggcatc ggatacggca tcgccgaggc gctcgtcgcc cgcggcgacc gcgtcgtcat
     2701 caccggccgg gacgaggaga gcctgaagcg ggcggccgag gcactcggcc ccgaccgggt
     2761 gctcggggtg cccggcaagg cccacgacga ggcccaccag gccgccgccg tggagcgcgc
     2821 gatggacgcc ttcggccgca tcgactacct cgtcaacaac gccgggacca accccgtgtt
     2881 cggcccgatc gccgagctcg acctggccgt cgcccgcaag gtcttcgaga ccaatgtgat
     2941 ctccgcgctc ggcttcgccc agcagacctg gcgggcgtgg cagaaggaga acggcggggc
     3001 gatcgtcaac atcgcgtccg tcgccgggct gggcgcgtcg ccgttcgtcg gcgcgtacgg
     3061 catcagcaag gccgccatgg tcaacctctc gctccagctc gcccacgaga tggcccccgg
     3121 cgtccgcgtc aactccatcg cccccgccgt cgtgaagacg aagttcgccg cggccctcta
     3181 cgaggggcgc gaggcggagg tcgtggcgtc gtacccgctc ggcaggctcg gcgtgcccga
     3241 ggacatcggg ggagcggccg ccttcctgct ctccgccgcc gccgcctgga tcaccgggca
     3301 gacgctggtg gtggacgggg ggatcttcct caacgcgggc ttctgaggcc gcgcggcggg
     3361 cgatgtcagt ggccgccggt aagttctccg gtgtaaacgg atcgaacccc ggaggttgtc
     3421 gacgtgaccg tcaccgacac gctgcccgag tcctggcgcg gagtcctcgg cgaggagctg
     3481 gagaagccct atttcaagga gctcaccgac ttcgtcgagg aggagcgggc gaacgctccg
     3541 gtgtacccgc cgcgcggcga ggtcttcgcc gcgctggagg ccacgccgta cgagcgggtg
     3601 aaggtcctcg tcctcggaca ggacccctac cacggggcgg gtcagggaca cggcctctgc
     3661 ttctcggtcc ggcccggcgt caagaccccg ccctccctgc gcaacatcta caaggagatg
     3721 cgcgaggagc tcggctacga cgtcccggac aacggctacc tccagccgtg ggccgagcag
     3781 ggcgtcctgc tgctcaacgc ggtcctcacg gtccgcggcg gtgagcccaa ctcccacaag
     3841 ggcaagggct gggagaagtt caccgacgcg gtcatccgcg ccgtggcctc ccgccccgac
     3901 ccggccgtct tcgtgctgtg gggcaactac gcccagaaga agctgcccct gatcgacgag
     3961 acgcgccaca cggtcgtcaa gggcgcgcac ccctcgccgc tgtcggccaa gaagttcttc
     4021 ggcagccgcc ccttcaccca gatcaacgag gcggtcgcgg cccagggcca cgaagcgatc
     4081 gactggcgca tcccggacct ggcggtctga gcccggtccg cgcgtgaggg tgtacggaca
     4141 cggccgcggc gcccgcccgg ctcagtgccc gtacacctgg ccgcagatgc ggttggcgtc
     4201 gccgccctgc tgccagcggc cgtagtcgcg gcccatggcg cagacattgc cgccgccctt
     4261 ggccggtgcc ggggcggggg cgggcgcctc gtggcggggc tcggaggcgt ggccgctcgc
     4321 gggcgggtcc gagtggtgct ggggggcggg ggtgtcctga cgcggtgcgg accgctccgg
     4381 ggaggccgcc tgagggcccg cgtcccggga ggggccggac gagcccgggg ccgagcccga
     4441 gtccgagggg gacgaggagt gcgcgctccg gccgggggag cggtcggccg ggcccgagga
     4501 gccggccggg ccggacggcc cggaggggcc cgagcgggcc gggcgatccg cgtggccgga
     4561 ggggccggaa gggcctgagg ggcttgaggg gtccgtgaat acggaaggcg cggaagggtc
     4621 cgccggattc cagaacctct ccaggtcccg gggggctccg gggtgcgaga ggtcggacgg
     4681 gtcccagaac gtcggtgcgc cgcccagccg gtccggatcc ccgccgcgcc cggtgcgggg
     4741 accggcaccc gggccgtccg gccccgtcgt ggccagtgcc tcgcgggccg ggcccgggcc
     4801 ggtgcgggga ccggagcccg accaccgcga cgagccggcc ggggcgtggg cggcggtgtg
     4861 cggggacacg gatacgcagc cggtggtggc catcatcgcc accaccgtca gggctgccgc
     4921 tgcggggact cgatgcactc gctcaactct gctgccctgg ggagggggtt gggaatgccc
     4981 cggaggggtg atgtgcgatc atccgcctgc cggcggggct ttccccaccc cgccccttcc
     5041 cgtaaccggg ggcttcgccc ccgggccccc ttccgcgctg acgcgcggtg tcctcaagcg
     5101 ccggacgggc tgatttcagc ccgtccgggg gcacctccca gcggtagctg ggggagcttg
     5161 aggaccggag cccggggcgg agcccctcac gcggcggagc cgcacatcgg atgcggcggg
     5221 aaggggcggg actgcggaaa ggtcacccca gcaccccccg caacaactcc cgcgcgctga
     5281 cccgcaaccc ctccaccccc ggcacctccg cgtggtacga ccccgccgcg cacgagaaca
     5341 tcaacccctc gcaccaggcc agcaccgaca gcgcgtgccg ctccggggcc ttcgagcccg
     5401 ccgccgtcag cagcgcgacg aggggctcgc ggaaggcgcg gccctccgtg tcgtagatgg
     5461 ctcgcagctc gggccggcgt gaggcctcca gggccagttc gtagcgggcg atcaggagtt
     5521 cgcgccggcc ggtcagggtg cggtgcaggg cgagcgcgat cgcgtcggcg agcgcttcgg
     5581 ggccgtccgc cggatcgggc agttccttca gggccagcac ctcgccctcg cgcacggcga
     5641 gccgccgcac cgccgcctcc agcagcgcga gccgggtccg ggcctggttg gacgtcgagc
     5701 cggtcggcag gcccgccgcc tcgtcgacgg cccggtgggt cagcccgcgc atgccgcgct
     5761 cggcgagcag gtcgagggcg gtgtcggcga tcagccggcc gcgggcggct ccggcgggca
     5821 gccgcaccag cggcttccca gggtactgcg cgggttcctt ctccactgac atgccttcaa
     5881 cctaccgccc gcactacagg ggtagtatcg tcaggcgaac tacaggcgta gtcatccgga
     5941 ggtaagtcca tgcgagagct ccgagccgtc gtcatcggtg gcggggtggg aggcctcacc
     6001 gccgctgccg ccctgcacca ccgcggctgg gacgtcaccg tcctcgaacg cgccgcctcg
     6061 ctcgaacccg tgggcgccgg gatcgccctc gcggccaacg cccagcgcgc cctcgacacc
     6121 ttcggcgcgg gcgacgccgt acgcgccctg tcggtcccgc aggtggacgg cggactgcgg
     6181 cgccccggcg ggtactggct ctcccgcacg gacaacgcgg ccgccgcccg gcgcttcggc
     6241 ggccccgtcg tcgtcgcgca ccgcgccgac gtcatcgccc tgctcgcctc ccggctcccc
     6301 gagggcgccg tgcgcaccgg ggtccgcggg gaactcgccg accccggcgg gccggaccgg
     6361 cccgcccgcg tcaccacccc cggcggcgtc ctggaggccg agctcgtcgt cggcgccgac
     6421 ggcatccact ccgccgtccg cgccgcgctc ttccccggcc acccggcacc gcgctacacc
     6481 ggcttcacca cctggcgctt cgtcgtcccg gcggcggccg cgccgcaggg cgggaccacc
     6541 gcccacgaga cctgggggcc cggccggctc tggggcaccg tcccctgctc gacggccgcg
     6601 tctacgccta cgcccaggcc gccgcgcccg cccgcgcgca gtccccgggc ggcgaactcg
     6661 cccagctgcg ccgcctcttc ggcgactggc accaccccgt gccggagctc ctcgccgccg
     6721 ccgaccccgc cgccgtgctg cgcaacgacg tccacagcgc cgccgacccg ctgcccgccc
     6781 accaccacgg ccgggtcgcc ctcctcggcg acgccgccca ctccatgacc ccgaacctcg
     6841 gccagggcgg ctgccaggcc gtcgaggacg cggtcgtcct cgcccacctg gccgccgagg
     6901 ccgccacggt gcacggcggc gacccgctgc ccgcgctgcc gcgctacacc gccgagcggc
     6961 tgccccgcac cacggcggtc gtccgccgct ccgcccgcgt cggccgcctc gcctgtctct
     7021 cctcccggtc cggccgcctc ctgcgcgacg ccgccctcgt cgcggcggac cgcttcgcgc
     7081 cccacctcgc cctgcgcggc ctcgacggag tggccgactg gcgcccaccc gcacacccgt
     7141 atgctgctca aacgggaacg cgtaccaagg aggctccgtg aaggtcggct gcatcgggct
     7201 cggcgacatc gcgcagaagg cgtacctgcc ggtgctcacc acacagccgg ggctcgaacc
     7261 ccacctccac acccgcacgc ccgagaccct ccaccgcgtc gccgacacct accgcgtccc
     7321 cgacgcgcac cgccacaccg acctcgactc gctgctggcc gccggcctcg acgcggcctt
     7381 cgtccacgcg gccaccgccg cgcaccccga gatcgtcacc cgcctcctcg aagcggacgt
     7441 gcccgtctac gtggacaagc ccctcgccta cgacctggcc ggcagcgcgc gcctggtccg
     7501 cctcgcgcgg gagcgccggg tgagcctggc cgtcggcttc aaccgccgcc acgcccccgg
     7561 ctacgcccag tgcctggacc acccgcgcga cctgatcctg atgcagaaga accgggtcgg
     7621 gctcgccgag gacccgcgca ccctcgtctt cgacgacttc atccacgtcg tcgacaccct
     7681 gcgcttcctc gcccccgggc ccgtcgagca cgtcgacgtc cgggcccggg tccgcgacgg
     7741 cctgatgcac cacgtggtgc tccagctgtc gggcgacggc ttcaccgcca tcggcacgat
     7801 gaaccggatg agcggctcca ccgaggagat cctggaggtc tccggccagg acaccaagcg
     7861 gcaggtcgtg aacctcgccg agatcgtcga ccacaagggc cagccgagcg tccgccgccg
     7921 cggcgactgg gtgcccgtgg cccgtcagcg cggtatcgag caggtcgtcg gcgtcttcct
     7981 cgacgcggta cgggcgggcg aggtgctgga cgccgaggac gcgctgcgca cccatgagct
     8041 cgccgaacgg gtcgtcaacg ccgctctgga gcaggcttcc tgacggttcc tccggaacgc
     8101 ctccggcgca gcgcccgcgc ggtcgcggcg gcggcgtagc agaccaggac cgtgaccgag
     8161 ccgaggaccg cccagtcgcc ggtgcggacg tacgggctgg tgccccgggc gaggggcacc
     8221 tcgtagacgg cggcggcgct gcgctccgtg cccagcgggg cgcccaccgt ctccccgcgg
     8281 gggccggcga ccgtgctcac cccggtcagc gtcgcgtgca ccacgggccg ccaggtctcg
     8341 gcggcccgca gcgccgccag cgaggcgtgc tgccgcggcg cccagctgtg ctggaaggtg
     8401 gaggtcgccg actgggcgac gagcaccccg gcgccgtccc gcgccagctt ccggctcatg
     8461 tcgggaaagg ccgactcgaa gcacaccagc ggtccgatcc gcagcccgga cggcagccgc
     8521 atcaccaccg gccgttcgcc gcgccgccgg tcctcgcccg cggccttgcc caccgaggtg
     8581 gcccagccca gcagcgagcg cgccgggacg tactccccga acggcaccag ccgcattttg
     8641 tcgtaccggt ccccggtggg gcccgtgggg ccgatcagca cggagctctt gaagatcccg
     8701 ggccggtccg cgcggcgggc gtcgacgttc accagcagat cggcgccggt ctcctgggag
     8761 agcgcggcga gccgcttccg caggtcgggc cgccggtcca gatcctcgcc cacgctgctc
     8821 tcgccccaga ccaccaggtc agggcgttgc ccggccagtt gccgggtcag ctcctcctcg
     8881 cggtcgaagc gccgctgcgg gctgtgcgcg ccaaagacca cgcccggctg gacgacggcg
     8941 atccggacgt tgcccgcggc ccgcggctgc ggggcccaca gccacccacc ggcggcgacc
     9001 gcggcgcacg cgagcgcgcc caccgccccg gtggcgcgtg cgcgcggggc acaaatcagc
     9061 gtggcgaggg ccgtgttgag ggccacgagg aggaaactaa ccagccagat cccacccagg
     9121 gaagccagtc tgagggcggg tggcacctgc cattgactcg ctccgaacag cccccagggg
     9181 ccacccaagt actcccacga tcggacaagt tcgaccatca accaggcgga ggggacgacg
     9241 acgagagccg ccgcgcaccg cccggcgccg ggtgatcctc ccagcaggcg atgcaccacc
     9301 agtccccacg gcgcccacaa caaccccagc agcgccgcga gtaccagaat gaagacatgc
     9361 agactcggca gcagccaatg gtgcaccgcg agcaggaaac cagccccgcc cagccagcct
     9421 tcgagcgccg cccggcggcc cgtggcggcc gagcggacca gcagcagcca cggcgcgagg
     9481 gccacgtagg cgagccacca cagggccggc gccggaaagc acagggcggg cagcgcgccc
     9541 gccaccacgg ccagggcgcc acggcgccag ggaccggcgc ggagcgggcc gtaccgccgg
     9601 accgacgatg ccatcgccat gccttgcctc cctcgggctc gacgatcacc agtgtcgggg
     9661 atcctcgatc atccgtccct gccaggtgtg agcgggatcc ggccatccct cagtttttcg
     9721 aacaacggag gatcatgagg aaaaaacccc gacaacggtg tgcaatattc aaccgttcct
     9781 acccttccgg agggcggctt tgactcgatt cgatcgaaaa cgatccgagg tgaaccttgc
     9841 gtcccgtgct ggaaaggtgt gaccggatat gcgtaacggg ttatccgcgg tccgccctgg
     9901 gcaggtaccg cgcaaaagtg gacaggaacg ctgcgagtcg gcctggggag gcggcgtgac
     9961 aagcgtgcga gaccgcataa cagtccagcc cttggagatc gtgcctttct actgtccgat
    10021 agcgccggcg gtccatcccc gggtgcggga gatcgacgac gcctcggtgg actggatgct
    10081 ccagcaggag ctcgatacct cttcccacca gcggcaacgc ctcatccggt gcgacttcgg
    10141 cggcctgacg gcgaggacca tgccctacgg gcaggtccgc ccgctgacgg tggtggcgaa
    10201 gctgcattcg gtgctcttct ccttggacga cgccctctgc gacgaggcgg gcgccacggc
    10261 tcacggcctt gcccatacga cctcccgcat catgcgcgtc ctggaggcgc cgacaccggc
    10321 ctggccggac gactcgcccc acgcggcggc gctccgcgcc gtccgcctgg agctggccga
    10381 gcacgccacg cccggccagt tacgccactg gaccgaaggc atgcgcacct atatgtccgg
    10441 cctggtgtgg gaggcggcgt gccgccgcga ccgggcactg ccgtccgtca acgactacgc
    10501 cgccatgtgg atgcgcgcca tcggcatggc gccgtccacc gcgctcatgg acatcgccgg
    10561 ggggtacgag ctccaggacc aggacctcga ccggcccgag atccgggcca tgaccgaaat
    10621 gacctggacc ctcgtggcct gggacaacga cttctactcg cggaacaagg agatccagcg
    10681 agccggtgac aacctcaacc tgatcgacgt cctcgcccag gaacgggact gcacgcccgc
    10741 ccgcgcgcag gaggaggcca tggcgatgcg cgaccgtgtc atgacgctct tcctgcgctt
    10801 gcgcgagcag ctctggcccc gctccggtgt cgagctgcgc tgctacctcg tggcgctcgg
    10861 ccagttcgtc cgcggccacc tcgactgggc ctccgcctgc gcccgttacg ccgatcccta
    10921 cgggagcggc gagcccgcgc ggtggtggaa gtcggccccg gccgacgaca gcccggagcc
    10981 gctgcccctg cccgccgtcg cctggtggtg ggaccaactc gaatccaccc cctatccgcg
    11041 ccgcagccag cggcgcaacg acctccacca cgacgtccgg gacggggtgg cccggccgga
    11101 cggcgccggc gtgaccaccg gctgttcgag ccgctccggc tgaacggagg aggccggtcc
    11161 ttccggtgcg cggtcctcgg cgggctccgg gggcagcggc ggctgtgccg cgaacttcac
    11221 cggaagggcc gtcaggtggc gggacatcag cgcggaggcg tagaccagtt cggactcctc
    11281 caccgccagg gtgaggtcgg gcagccgcag cagcagggcg tcgatgcccg tgtccgcgat
    11341 cgcccggccc acgtcctgcc cggggcactc gtgggcaccc ccgctgaacg ccaggtggga
    11401 gcggttcccg tggatcggca ggtccggatc ggggcggacc accgtgtcca tgttggcggc
    11461 ggccagcccg agcaccaggg cgtcaccctc cttgatcggc tgcccggcca gctcggtgtc
    11521 ctgggtggcc cagcggccga ggatggtgat gaagggcggc tcgtcccaca gcacctgctc
    11581 gaccgcgtcc ggcagcgtca tatggccgcc cgcgagcgag gcccggaagc ggacgtccgt
    11641 gaacaccatc ttcagggtgt tggcgatgag gttcgcggtg gtctcgtagg cggcgatgag
    11701 caccagccgc agatgctgct gcacctcgtc gtcggtgagc ccggaggggt gctccagcag
    11761 ccagctcgtg aagtccgagc ccggctccac ccgcttgcgg gccaccagct tgcggagcgt
    11821 ctcctggacg aactcgttgc tcgcgaccgc cgtctcggtg cccttgatca tgtcgcgggc
    11881 cgcgttgacc agccgggtgt cgtacgcctc tggcatgccc agcagctggg tcatcgccat
    11941 catcggcagg tgctccgcga actggtgcac cagatcggcg cggcccgcct cgcagaagcg
    12001 gtccaccaac tggttggcga agcgggtgac atggcgccgg atgccgcgct tgtcgaagcg
    12061 cgcgatgccg tcgttgaccg cgccgcgcca gcgctcgtgc tgctgcccgt ccgcgaagac
    12121 gcagatgggc tgccaggtgg tgatcggcgt cagcgggtgg tccggggcga tccggccctc
    12181 gcgcgcctcg cgccagagcc gggagtcccg cgagaaccgc gagggggtgc gcgcgacgtc
    12241 gaggttctcg cggtagccga gcaccagcca ggcgggcacg tcgccgtgca gcaggacggg
    12301 cgccacctgg ccgtgcttct cgcgcagccg ctcgtacagc cccatggggt cggcctcggc
    12361 ctccggtccg tagagccggg tgacaccgcc cgggccgtgg gcggggcact gcgggggagg
    12421 cacggccatg gagtcggcgc gggagtgttc gggggggagg gtcactgagg ctccggggag
    12481 gcggtcgtga gggtgtacag atagcgcatg agggtcagca gggtgtcgcg gcaggagccg
    12541 cggtcccggg cgtcgcagtc gaccatgggc acggagtcct ccaggtccat cgccgcgcgg
    12601 agctccgcca tggggtaggt gggggagccg gggaagcggt tgacgcccac gacgaacggg
    12661 acgccgcgct cctccaggcg gccgatcacg tcgtagctca cctccagccg gcgggtgtcg
    12721 agcagcacca ccgcgccgag cgccccttcg aagaggccgt tccacaggaa ccagaagcgc
    12781 tcctggccgg gggtgccgaa gaggtacagc accagctgct cgttgatgct gatccggccg
    12841 aagtccatgg ccacggtggt ctcggtcttg tgctcgaccc cggccaggtc gtccacgccg
    12901 acaccggcct gggtcatggt ctcctcggtg gtcagcggcc tgatctcact gaccgcgccc
    12961 accagggtcg tctttcccac gccgaagccg ccgacgatga cgaccttgac ggccgcggtg
    13021 gcggacgccg gcaggacgtc ctcgcgccgc ggccccgcgg gggtgtcggg gccgtacggg
    13081 gaggcgtacg ggtcagagct tctgtagtcc attcatcacc gcctccagaa gtcggacgtc
    13141 gggcagggcc gccgccggga ccggggggcg ggcctccacc tgtcggcccg ccagcaattc
    13201 ggtgagaagc tgggtcaggg tgctgaccgg cagctccaga taagcggata tctccgcgac
    13261 ggagagcggg tagtgacaca tccggacgat ggccgcgtgc tccggctgga gaccggcctc
    13321 ggactccgtc cgggacacga tcagggtgac gagatcgagc tcggtccgcc gctgctccgc
    13381 gcggtcctgg ccgccggtga ggatgtacag ccggtccgga ctgccgggcg ctgtcgctgg
    13441 gtcgggtccg gccccgttca tgtcaccggc ccgccgaccc gggggggact ggtgaggtgc
    13501 gagccgatgc gggccaccag gtcccgcatc cgcaggccca tcagctcggc gtccacgtcg
    13561 tcgtcggcca gcacggcgag atacgctccg gccccggcgg ccatgaggta gaagaaaccg
    13621 ccgtcgacct cgatgacgac cagccgcatc tgtccgtccc cgcgcggatt cgggaactcc
    13681 gcggcgatgg cggcggacag gctctgtagt ccggcacacg cggcggcgag acggtcggcg
    13741 acgtcagggt cggtgccgtg ctgggccatg cgcaggccgt ccgaggacag cacgatcacg
    13801 tgccgggtct gcggaacgcc cgttgccagg tccttgagca tccagtccat gttgaaccgc
    13861 ggctgcgtca cttggctact cttccttgtc tgacgagaga tcactgttcg gccggtcggg
    13921 atccggctcc gggagctccc cgttgatgcc tctggtgaag gccgccagcc acatgccggg
    13981 ctgcttgggc ggctgctccg ggaggctgtc ccgctcgggc cccggctgca ccgggacgct
    14041 cggccgggtg cgcatcgcct gctcccgctc cctttcgcgc tgggcggccg cggcccggcc
    14101 gaaggggagc ggcgcgggcc cgcgccgccg ccggcgctgc ggcagtccgc tgtcgcccag
    14161 cggcggcggg atggggtgct ccatcatggg cggcggcgtc tcggggccgg gcgcggggat
    14221 tcgctggccg gggcgccgct tggacttgaa ggggggcagc ttgggggcgc gggcgatgtc
    14281 gccgccgggg tgcttgctgg cggtgatcag gtccatgggg atgaccagga ccgcccgcac
    14341 gccaccgtag gcggagggcc gcagcgacac caggaagttg tacgagcggg cgagccgcgc
    14401 gacgaccgcc aggcccagcc ggggcgcctc gcccaggtcg tcgaggtcga gctcgctctc
    14461 cttggacagc acccggtcgg tgcggcgcct ggcctcgtcg gtcaggccga cgccggcgtc
    14521 ctcgatctcg accgcgatgc cggactggat gtccacggcg gtcaggtgca cccgggtctg
    14581 cggcggggag tagcgggtgg cgttgtccag gagctcggcc agcgcgtgga tcaccggctc
    14641 gacggcgggg ccgaccacgg cgacgtccgc gacggagtgc aggtcgacgc ggcggtactc
    14701 gaggatccgg gacatggcgc cgcggagcac gttgtagagc gggatctcgt tcttccactg
    14761 gcggcccggg cgggagccgc cgagcacggc gatgctgtcg gccaggcggc cggtcagggc
    14821 gttgccgtgg tcgaggtgga ggagatcgcc gaagacgtcc gggtcgttgc cgtgcttgtg
    14881 ctccatctcc cggatgtcgt aggcctgttg gtggacgatg gcctgcaccc ggcgggcgat
    14941 gttgacgaag gcgcgctgcg cggagtcgcg catgctctcc tccgcctgga ccgcctcgat
    15001 gacggacttc agcacggagc ggtgcgccgc ggcgtagccc ggctccaggt cgtgcgtcgg
    15061 cagggtgtgc cggaggatca cctccgtggg ctcaccgcgc ttcagcaggc ggaccgcccg
    15121 gggcagcagc tcacgggcca accggaaggt ctccgcctcg tgttcgtcga gccggtaccg
    15181 cagcgcggtc tcctgctcgg cgcaccggcg gcgcagggtg gtgatcaccc ggccgcgccg
    15241 ggccgcctcg gaggccgcca gtgccaccgc gaccgtggcc gaggagccgc accagccgac
    15301 ggggacgcgt gcctccgggg tcacggcgac caccgcggtt cccgtgcaca ccgccagcac
    15361 cagaggtgag atcagccata tcagcgcgga gacgggccgt cgccggtctg acgagccagt
    15421 accaaccatc gggatcctcg gaactcttgg aaacgcagga gaaaaagggg cgtgggtgcc
    15481 ggagcgcagc ggtcttcgcg gtctcgcgga gaacggcgac agggcggcac tcgtccgcag
    15541 cgtgcggtgg gcgtgcactg gttgtgcagc agccatgcac tggccacaac ccgctgcgcg
    15601 acatggagcg tagccggtcg tcgaggtgct ccggcgcgaa gttgtcatat tcgcggattg
    15661 gcctgacggg ggaattggca aggcctcata atgaccccac gtcacaaata ccgaatgtgt
    15721 ttccgcattt cctggataaa tgttcgatca tgccggggtg agaggtcccc ggcggccgga
    15781 accgcgccgg cgtcacaccg cgtgagcacc ggagtcacgg gggtgtcgta cgcgcggtgc
    15841 caccggatgg ttgcgggcac ggctcgaagg tcacgctccc gggtggtgcg tccggcgaac
    15901 cctgcccctg gcccggccga ccggactagg ctcgccccca ccacatcctc ccgggagtca
    15961 acgccatgtc agggcctcag cgtgaacaga acgcagccgc cgccctgttc gagcgtgagc
    16021 ttgaacttga gacagcggaa caggcggtgc accgcctgtg cgggcacgtg agtgaaggga
    16081 ggagccggct cggcggactt ctgctctaca gcggcgaagc gggcctgggg aaaacgtcgt
    16141 tgctctccga actgcgccgc atcgccaccg agacggagcg ctgcaccgtg ctcttcgcgc
    16201 gcggcagcga gtcctcgcgt tccgtgccgt tcaacgtcgt gcgccagctc ctccagccgg
    16261 ccctcgcccc gatgaccacg gcggcccggc aggacctgct cagcggctgg tacgacatcg
    16321 ccggccccgc gctcggcatc tcgccgccca gcggcccgca ggacccacag ggcgtgcgcg
    16381 acggactcga ctggctggtc acccaactcg ccatgaaggg cgaccccgtg gtcgtcatca
    16441 tcgacgacgt ccactggtcg gacgccgagt cgctggcgtg gctcacctcc tacgccgtgc
    16501 ggctgcgcga gatgccgctg ctggtcgccc tctcctaccg cccgcacgaa ctgcccgacc
    16561 acaccccggc cttccgcgac ctcgtcgaag gccgcagcgt gcgccccgtc gagctgcgcg
    16621 ccctcacgcc cgacgcggtc gccggcctgg tgcactcggc cttcgacggc aaggcggacg
    16681 ccccgttctg ccgcgaggtc tgggccgtca ccggcggcaa tccctacgag gccgtggagt
    16741 tgatcgccaa ggcccgggag cgcgacctca agccgctgga ggagtccgcc gccctcctgc
    16801 gggagctggg cgccgccgcc cggggcagcg gcctcgtggc ccgcctggac agcctgggca
    16861 acgccgtcac ccggttcgcc ttcgccgccg cggtcctcgg cacggagatc tcgcccaccc
    16921 tcgccgcgaa cctcgcgggc atgggcccgg cgcagggcgc cgactgcgcg gacaagctgc
    16981 gcaaggcccg tatcctcacc ggcgtccacc agctggagtt cgtgcacccg ctgatcgcca
    17041 ccgcggtcta cagcgcgatc cccgcggcca cccgcaccgc gatgcacggc caggccgcgt
    17101 gggcggtctc cgaggcgggc cagggcgccg ccgtggcctc ccgccatctg ctggaggtcc
    17161 accccgacca cgaccccgag ctggtcgaac agctgcgggt ggcgtcccgc gagcacctcg
    17221 ccgtcggcgc cccggacgcg gcccgccgct gtctggagcg cgccctgcgg gagccaccgc
    17281 ccgaggagga gcgcgcctcc gtcctctacg agctggcctg ctccaccctg ctcacctcgc
    17341 cgtccaccac catcaaccac ctcaagtccg ccctggccct gccgcacctc accgaggagc
    17401 tgcgcgtgga cgccacctac cgcctctccc aggtgtacgc gcacaacaac cagctcaagg
    17461 aggccgccga ggtcctctcg gtgcaggcgg cccgcacccc gccgggcgcg gggcggatgc
    17521 ggctccaggc cgcccactat ctgtggaagg gcatccagtc cgaggaggtg gacgcgcccg
    17581 ccaggtcccg gcggatctcc gagctcgccg accacctgcg gggccgggac gacgccgagc
    17641 gggccctgct cgccatccgc gccttcgacg gcgtgatccg cggcgaggac gccgtgcagg
    17701 tgctcgaccg gatcgagcgc gcgctggtgg acggccggct ggcccacggc atgagctgga
    17761 ccaacaccga gtggggcttc gaactcccca gcatcgtcgg catcagcttc ctctacaccg
    17821 accggctcga ccgcgccaag gagctgttcg aggaggccat ccgagccttc gagatctccg
    17881 gctggagcgg catccacctc gccttcgccc atgacttcct cggctacgcc taccgtcgcc
    17941 tcggtgagct cgacaaggcc gagaagctgc tgcgcgaagg gctgcggctg gcctaccggc
    18001 tgggtcccgg gctgcccatc cagtgggacg gcacctgcat gctcatcgac acgctgctcg
    18061 cccgcggcga tgtggcggag gcgcaggtcg tcgccgagga gaacggcttc cgcccgccct
    18121 acaccccggc ggtcgtgctg cccgacgcca tgtgcctcgc cggacgcctg atgctcgccc
    18181 aggggcggcg gaaggaggcc gtcgccgagc tggaggcggc cgggcgcaga ctggaggagc
    18241 gcggacggca caacaccgtc tgggcaccct gggcactcga tctggccgtc gcggtcgcgc
    18301 ccgacgaccc ggagcgcgcc cgcaccctct cgggccaggc cgtgcggaac gccgcccggt
    18361 tcggcaccga ctccgcgctc ggtgaggcgc tgcgcatggc ggccaaggtc gcggagccgg
    18421 aggacgccct gaagatgctc gaccagtccg tggggcacct gcgcaagtcc ccgtgcaagt
    18481 acgagttcgc ggccgccctg gtcgaccacg gcgtcgccct gaacggtgcc ggccgtacgg
    18541 ccgaggccga ggagcggctg cgcgagggcc gggaggtcgc cgagttctgc ggtgcgcacg
    18601 gtctggtcag gaccgtccgt tcgctgctgc ccgaggccgt gtgcggggag gccgagccgg
    18661 cgggctgacg ggcgggccgc gcgggcccgc ggcactcagg aggcgcggcg gccggtcttc
    18721 ttggccgcgg tcttcttggt gctcttggcc gtggtgctcc tggccgttgt cttcttcgcc
    18781 gtggaggacg agttcttcgc cgtggaggac gaggacgagg tcttcctggc cgccgcgctc
    18841 ttcttgggcg cggcggtctt cttgccggtt ccgcgcgcag ccttcgccgc cggcgccttc
    18901 ctcccggccg ccggctccga gggcttcttc cccgcggagt cgatggacgc ctggagggcg
    18961 gccatcaggt cgatgacgtt gtcgggcgcg ggagccgtct ccttgcgggg cacggggcgg
    19021 tcggacaggt gcgcgtcgat cagctcgcgg agggcgacct cgtactcgtc ctcctgctcc
    19081 gccaggtcga agtcctcgga gagcgtgtcc atcaggctcg tggccatctt cagctcctgc
    19141 ggacgcacgg tgaccgaggc cggcggggcc aggtcgccgc tgtcgcggac ctcgtcgggc
    19201 cagtacatgg tgtgcagggt cagcaggtcg ccgtggacgc gcagcagggc cagcgactcc
    19261 cgggtgcgca gcgcgatctt ggtgacggcc acccggtccg tctgcttcag ggtctccctc
    19321 agcaggacgt acggcttgtt cgccgccgcg ctctccggcg ccaggtagta cgagctcgcc
    19381 agctggagcg ggtcgatgcg gtccgagtcg acgaaggcca ggacgtcgat gagcttcttg
    19441 ctgggcagcg gcagccccgc cagctcgtcc tgggtgacga ccgcggtgtg gccctcgtcg
    19501 tcctcgaagc ccttggcgat gtgctcgtag tcgatctgct caccgcacac gtcgcagacg
    19561 cgcttgaggt ggatccggcc gccgtccttg tcgtggacct ggtgcagccg gacgccgtgc
    19621 tcctgggtcg cggcgtacag ccggaccggc acggacacca gtccgaagcc gatcgcacct
    19681 ttccacatcg ttcgcatagt ttgttccctc cacggggaat tcctacctta tgcccgcatc
    19741 ctcggaccgg caggcggtgg agatcgaggg gcaccggttg tccctctccc acctcgaccg
    19801 ggtgctgttc cccgcctcgg gccacaccaa ggcgcaggtg ctgcactact acgcccgggt
    19861 cgccggggtg ctgctgccgc acgccaccgg ccggcccgcc tccttcgtgc gtgccccgga
    19921 gggcctcacg ggccagagct gggtggccaa gaacccgccg ggcggggtgc ccggctgggt
    19981 gtccgtggtg ccggtcgagc accgggaggg cgtcaccgag caggtcgtga tcgactccgc
    20041 cgccgccctg atcgccatgg cgaacctcgg ggcgtacgag gtgcacgtcc cgcagtggac
    20101 ggccgcggcc gggcccgacg cgcacgaccg cctcgtcctc gacctggacc cggggcccgg
    20161 cgccgacctg gtgctgtgct gccgggtcgc gcagcggctg cgccagctcc tggacgacga
    20221 cggcctgacc gcccacgccg tcgtctccgg ctccaagggt ctccacctct acgccgccct
    20281 gtgccccaca cccggccggg cggcctccgc ctacgccaag gagctggccg gccggatgca
    20341 gggggagcac ccggggctgg tggtggcctc catggcacgc gcggcccgcc gggggaaggt
    20401 gttcatcgac tggtcgcaga acgcgagcgc caagaccacg gccgcgccct acaccgtccg
    20461 gctgcgcgac cgcccgggcg tcgccgcccc ggtcggctgg gacgagatcg ccgcctgcgc
    20521 ggaccccggg gagctcgcct tcaccccgga ggaggtgctc gaccgggtcg ccgcccacgg
    20581 tgacctgctg gcgccgctca ccggggacga cacccgccgt ccgctgccct gagcgggcgg
    20641 ccggcgcctc acagccgggt caggtcgggg cgcagccggt gccaggtcgg gtggcgcaga
    20701 tggcccgccg gggtccagcc ggagaaggtg acctcggcga tgagccgggg ctcgacccag
    20761 tgcgcgcccg ccacccccgt gggccccgcg aagggtgact ccgggcgggc caggacctcc
    20821 agatagcggg cgaggtcgcg ccgctcgcgc tcggacagcc ccgagccgac ggagccggtg
    20881 aagcgcaggc cgcccggctc gtccaggccg gtgaggaacg ccccgggcag cccggtcagc
    20941 atgccccggc cctcggccca gccgccgatg accacatcga tggtcgtcac atgcttcgtc
    21001 ttgcgccact cgggtgagcg gacgcccggg aggtagaggg aggagagccg tttcgccagc
    21061 acgccctcga agccgtcctt gagggtggcg tcccaggccc gccggccgtg cccctccatg
    21121 taggcgggca ccgaccagtg cgt
//
