LOCUS       NZ_CP021744            20933 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces albireticuli strain MDJK11 chromosome, complete genome.
ACCESSION   NZ_CP021744
VERSION     NZ_CP021744.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces albireticuli
  ORGANISM  Streptomyces albireticuli
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8144417)
  AUTHORS   Wang,Y., Du,B., Ding,Y., Liu,H., Hou,Q., Liu,K., Yao,L. and Wang,C.
  TITLE     Streptomyces albireticuli Genome sequencing and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8144417)
  AUTHORS   Wang,Y., Du,B., Ding,Y., Liu,H., Hou,Q., Liu,K., Yao,L. and Wang,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2017) Department of Mcrobiology, Shandong
            Agricultural University, No.61 Daizong Street, Taian, Shandong
            271018, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 2.3
            Expected Final Version            :: yes
            Genome Coverage                   :: 88.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 07:12:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,975
            CDSs (total)                      :: 6,876
            Genes (coding)                    :: 6,711
            CDSs (with protein)               :: 6,711
            Genes (RNA)                       :: 99
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 165
            CDSs (without protein)            :: 165
            Pseudo Genes (ambiguous residues) :: 0 of 165
            Pseudo Genes (frameshifted)       :: 74 of 165
            Pseudo Genes (incomplete)         :: 97 of 165
            Pseudo Genes (internal stop)      :: 5 of 165
            Pseudo Genes (multiple problems)  :: 9 of 165
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:17:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1316316
            Orig. end                         :: 1337249
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP021744.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20933
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="darobactin"
                     /region_number="13"
                     /rules="((cds(PF04055 and (TIGR04085 or SPASM)) and
                     darobactin_precursor) or darobactin_rSAM)"
                     /tool="antismash"
     cand_cluster    1..20933
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((cds(PF04055 and (TIGR04085 or SPASM))
                     and darobactin_precursor) or darobactin_rSAM)"
                     /kind="single"
                     /product="darobactin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20933
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10933](-)"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and darobactin_precursor) or darobactin_rSAM)"
                     /neighbourhood="10000"
                     /product="darobactin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10933)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="((cds(PF04055 and (TIGR04085 or SPASM))
                     and darobactin_precursor) or darobactin_rSAM)"
                     /neighbourhood="10000"
                     /product="darobactin"
                     /protocluster_number="1"
     gene            complement(310..1125)
                     /locus_tag="SMD11_RS05640"
                     /old_locus_tag="SMD11_1161"
     CDS             complement(310..1125)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014179412.1"
                     /locus_tag="SMD11_RS05640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1161"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_087925377.1"
                     /transl_table=11
                     /translation="MDIEVLGELAVYENGVSIVPSAGKPRQILALLSLWAGRVVPVPTL
                     MEELWGDAIPRSAATTLQTYILQLRRRMAVALRDAPESPARTPKDVLATAFGGYRVAVT
                     PESCDWSQFRRLAGQGHDALLAGDARSASAHLTRALALWRGPALVDVPVGRVLGLETLY
                     MEETRMQALEERIEADLRLGYHAALLGELRTLVARHPLHENLCAQLMTALCRSGSPWRA
                     LQEFRQLRERLRRELGVEPSPRLQRLHQAVLSGAPELDGGEAFVQARSA"
     gene            1393..2598
                     /locus_tag="SMD11_RS05645"
                     /old_locus_tag="SMD11_1162"
     CDS             1393..2598
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.4"
                     /locus_tag="SMD11_RS05645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1162"
                     /product="histidine kinase"
                     /protein_id="WP_087925378.1"
                     /transl_table=11
                     /translation="MVVLSKGEPPPWLATGIVLAVQSAVAVLGFLNLLASRRPSAGHIC
                     LFLAAFVAVFVLQGIHCAPRAGRFRARHGRRTLALQALLTYAPLFALGLTWAGMPGFLA
                     GSALLILEPPLSVAAFAAAAVLTGTCTLLAGQQPLGVAIGVLSCGVNGLMVYGVTRIAS
                     WSAEVRRARDEVARLAVEGERLRVARDLHDLLGYSLSAITLKGELVARLVDKDPERAHG
                     ELREVLDISRQALADVRCVAHGYRQLSLTAELDSAARILSTAGITVEVHDERLPLREEA
                     GTVLATVVREGVTNILRHSAAQNCRITVSRTAGTLALDMAGDGIPGDTGERMARRSGGG
                     LDNLARRLEGIGGTFRACAGEDGWFRIFAECPADAAGPPRDVSGSSPSPWRSGRRPADS
                     VR"
     misc_feature    1402..1404
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2537..3172)
                     /locus_tag="SMD11_RS05650"
                     /old_locus_tag="SMD11_1163"
     CDS             complement(2537..3172)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468335.1"
                     /locus_tag="SMD11_RS05650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1163"
                     /product="response regulator transcription factor"
                     /protein_id="WP_087925379.1"
                     /transl_table=11
                     /translation="MIRILLAEDMHMVRGALVALLELEPDFRVVAEVADGRGILPSVIK
                     FRPDVAILDIDLPGVNGLDAAGLLWEQAPECRVIILTALEQRGTVRRAIDAHVRGFLPK
                     NAPPAELATAIRLVHSGRRVIDSRIPPTAWEAEDCPIAGRPTDSPLTRRETDVLKRAAD
                     GNSARETAREMHLSTGTVRNYLTSAVTKLTARNQLDAVRIAKEKGWIR"
     misc_feature    complement(3275..3286)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.87"
                     /tool="antismash"
     gene            3368..>3823
                     /locus_tag="SMD11_RS36990"
                     /pseudo=""
     CDS             3368..>3823
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012955.4"
                     /locus_tag="SMD11_RS36990"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAARCSDRSGGTVSQVRRKGSAGRLAEVADGVFAYVQPDGGWCLN
                     NAALVVSRGHSALVDTAATEARARALRTAALGVCPAPPRVLVGTHSHGDHTFGNFLFPE
                     ALVIGHERARGEMAEAGLHLTGLWPEVEWGELTLTLPEVTYRDRLTLH"
     misc_feature    complement(3837..3851)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.42"
                     /tool="antismash"
     gene            3909..4325
                     /locus_tag="SMD11_RS36995"
                     /old_locus_tag="SMD11_1164"
     CDS             3909..4325
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012955.4"
                     /locus_tag="SMD11_RS36995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1164"
                     /product="hypothetical protein"
                     /protein_id="WP_324614695.1"
                     /transl_table=11
                     /translation="MLITGDLVMSGVTPFCPMGSVTGTLDAVARLRALDARTVITGHGP
                     VAGPEVFDVTEGYLRWVQELAREGLAAGLTPLEAARAAGPGPYAHLIDSERLVPNLHRA
                     YAEERGAAPGVPLDIGELFREMVEFHGGLPTCRA"
     gene            complement(4295..4807)
                     /locus_tag="SMD11_RS05660"
                     /old_locus_tag="SMD11_1166"
     CDS             complement(4295..4807)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070488.1"
                     /locus_tag="SMD11_RS05660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1166"
                     /product="flavin reductase family protein"
                     /protein_id="WP_087925380.1"
                     /transl_table=11
                     /translation="MAVDAARFRALFGSFPTAVTVVTATDANGRPRGLTCNAVSAVSVE
                     PPLLLVCVHRNARTLAALRHSGAFVVNVLADGGQDAARVFTDRSEHKFAGVEWVPSAHA
                     RGAPVLVDVALAHAECVVVRTVEAGDHWIFIGRVEHAESYPRPPVLYHRGTFTVWDAQA
                     RQVGSPP"
     gene            complement(5097..5957)
                     /locus_tag="SMD11_RS05665"
                     /old_locus_tag="SMD11_1167"
     CDS             complement(5097..5957)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS05665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_1167"
                     /product="hypothetical protein"
                     /protein_id="WP_159395225.1"
                     /transl_table=11
                     /translation="MVVRRGLRRRTAVALAVASGVLGGFLPVGEAFAAPAGGKTTLTFS
                     EAKTTRMTVPDGVTKIVMTAVGPGGGGGGGGGGLVVFPTENSAIMLGGGGGAGGAAGGY
                     FQCTLNVTPGETLSIDVAGGGAGGAGGTLNWSNPTDGEAGKDTGGSTVHFPGGQQTAGA
                     PRGAGGAAGIRGQLDVGPGAGGTGSGATSGLGKGRCVGEPTTRPGAVPASGLAGTRVAG
                     GAGGAGARPYAVPPTCPAVAGRGGDGGEGGGASFDPLPAPPGTLGRLKGKPGQAGNLGC
                     VVLTY"
     misc_feature    complement(5937..5939)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    6236..6245
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            6700..7520
                     /locus_tag="SMD11_RS05670"
     CDS             join(6700..7042,7042..7520)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948817.1"
                     /locus_tag="SMD11_RS05670"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5 family transposase"
                     /protein_id="WP_087925382.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MADLVERLVPDELWVLFRRVVPPTEVIRPQGGGRRRAGDREALAA
                     IIFVATSGCTWRQLPPVFGPAWQTVYRRFAQWSRDRVWARLYRVILDELGARGELDWSR
                     CAIDSVSLRAGKGGPLTGPNPTDRGKLGSKIHLICDRNGLPLSLGISGANMHDSLGLEP
                     LVRGIPPIRSRRGPRRRRPAKLHADKGYDYDHLRRWLRKRGIRHRITRKGVESSQRLGR
                     HRWVVERTVSWLAGCRRLHRRYERKAEHFLAFVGIAAALIGYRRLAALLTA"
     gene            complement(7510..7866)
                     /locus_tag="SMD11_RS05675"
                     /old_locus_tag="SMD11_1170"
     CDS             complement(7510..7866)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016828129.1"
                     /locus_tag="SMD11_RS05675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1170"
                     /product="hypothetical protein"
                     /protein_id="WP_087925383.1"
                     /transl_table=11
                     /translation="MSYDLAVWEGERPADDKTAGRVFNDLYDRYIDSEVEEPPSERIAA
                     YVAALLERWCDLTEDEEDTSPWSTGPLIGEASGPLIYFPTRWSMAEEASAYAAAVAESM
                     GLICFDVQQNRLRP"
     gene            complement(7912..8490)
                     /locus_tag="SMD11_RS35310"
     CDS             complement(7912..8490)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS35310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_159395226.1"
                     /transl_table=11
                     /translation="MDRKRRSTRCRSAAVAVLSAAALMLSQGTSFAATGNWGFGVAAQT
                     VSPGSNVSWTPYVLCDPNPGPGTDPSPCSYSTTWRFKMGASNDGEFVNVGSSFSLVKRK
                     VTGETDVKVGTCNVVSSDEVTCAASGSGSVNPGEGFQPASPILLRTASSSCTETAYATW
                     FDTASEPQRPPNPGDNDDWQSLRTGGQCA"
     gene            8715..8963
                     /locus_tag="SMD11_RS05680"
                     /old_locus_tag="SMD11_1171"
     CDS             8715..8963
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS05680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_1171"
                     /product="hypothetical protein"
                     /protein_id="WP_087925384.1"
                     /transl_table=11
                     /translation="MDFRITAGEEQLLFVIVAHLDSGSAPTVEELSAEAGHDAHPDVAS
                     LRDKGWVLIDRQNTVIALSPMAVQAVRNLRFGQRVGA"
     misc_feature    9147..9162
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.33"
                     /tool="antismash"
     gene            9313..9564
                     /locus_tag="SMD11_RS05685"
                     /old_locus_tag="SMD11_1173"
     CDS             9313..9564
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020548497.1"
                     /locus_tag="SMD11_RS05685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1173"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_087925385.1"
                     /transl_table=11
                     /translation="MTASKINHRAPEPPYRQIAADLIRDIEAGSLEVGSPLPSENELVV
                     RCGVARNTVRNVVAHLRERGYVYTVPKRGTYVRQREQP"
     gene            complement(10001..10933)
                     /locus_tag="SMD11_RS05695"
                     /old_locus_tag="SMD11_1174"
     CDS             complement(10001..10933)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     darobactin: darobactin_rSAM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     darobactin: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     darobactin: SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="SMD11_RS05695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1174"
                     /product="radical SAM/SPASM domain-containing protein"
                     /protein_id="WP_087925387.1"
                     /sec_met_domain="PF04055 (E-value: 2.2e-16, bitscore: 59.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.1e-09, bitscore: 37.3,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="darobactin_rSAM (E-value: 1.0, bitscore:
                     1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDPRLRTCPSPRKLGFAWLEVTGFCNESCDHCYADSGPKGTHGI
                     MTVSDWQRVIDEFAAIGGRDVQFIGGEPTLYPHLARLIGHAHGAGLGIEVFSNMTVIRD
                     PLWEAFKSYGVKLATSYYSDDATEHDKVTNLRGAHKMTRANIRKAVELGIPIRGGVVAV
                     STQQRVREAVTDLQEIGVDHVGGDRTRAFGRASKGATPSVNDLCGHCALGQVAIGPDGA
                     VWPCVLGRFITLGNVRTTPLTEVWNSPRTIDARAEIAAAHGLKPAQSCTPPQFLPSCGP
                     CGPCVPSVAHCDPREADSQLATATIGAPA"
     misc_feature    complement(10916..10918)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11029..11181)
                     /locus_tag="SMD11_RS35315"
                     /old_locus_tag="SMD11_1175"
     CDS             complement(11029..11181)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS35315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_1175"
                     /product="hypothetical protein"
                     /protein_id="WP_159395227.1"
                     /transl_table=11
                     /translation="MPATTNPNTETADPEVIGSDTETADNEPTVPDDQSEQPEAIDLVG
                     AVLAN"
     gene            complement(11342..11578)
                     /locus_tag="SMD11_RS05700"
                     /old_locus_tag="SMD11_1176"
     CDS             complement(11342..11578)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS05700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_1176"
                     /product="hypothetical protein"
                     /protein_id="WP_087925388.1"
                     /transl_table=11
                     /translation="MSRTTTQKRQARERARAAQADIIKRYRAGESMNRLATQYEVSEPW
                     LCDRLDEWKEPRRDRAAALELRRDPSLGKPTGQ"
     gene            complement(11865..12083)
                     /locus_tag="SMD11_RS05705"
                     /old_locus_tag="SMD11_1177"
     CDS             complement(11865..12083)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS05705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_1177"
                     /product="hypothetical protein"
                     /protein_id="WP_087925389.1"
                     /transl_table=11
                     /translation="MLMLRRIFGLPVVPVAHTSGRPSMPREPEKPPCSECIELGIALTA
                     ARGLGDRVAEKRIQEQIVSHFDEAHCT"
     gene            12645..14000
                     /locus_tag="SMD11_RS05715"
                     /old_locus_tag="SMD11_1179"
     CDS             12645..14000
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413793.1"
                     /locus_tag="SMD11_RS05715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1179"
                     /product="hypothetical protein"
                     /protein_id="WP_087925390.1"
                     /transl_table=11
                     /translation="MATSARTPNEGLGRLLVQAKWSRSQFALIINRMGAEAGLTLHYDQ
                     SAVSHWIGGTVPKPPVRRLIVEALSRKLRRTVTHAEAGLPRAAEDEVPAGLDTVEEIVD
                     LGRADMDPSRRGLVATAGLFSAALVVPSFAGPARAVEALPAVPGKQTVRIGAGQVAAVR
                     KMTDKIADILDELGGAHARPMAAAFLVNTVVPWLRAEATDAVRKDFWAAASDLVYLTGW
                     MAMYERDHGTAQNYYVKALKLANRAEDHVTYCRTLRGMSLQASNLGYGPLALKFADSAA
                     EAAPKTGPRLQAFLAGQQAHATAMVGDHRRARRLLAATETALMKADNRRESIGGYDQSS
                     YAFHVSHVLYESKDLPGSIKALQQALKVQPPQERQGRVHFYGVLAQRQLEYGHLEAACE
                     SWTRFLEDYEHVSSARGDAHFDTMRLRLKPFKSSQAVRRMSARIADIALLKA"
     misc_feature    13026..13028
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(14103..14426)
                     /locus_tag="SMD11_RS05720"
                     /old_locus_tag="SMD11_1180"
     CDS             complement(14103..14426)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS05720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_1180"
                     /product="hypothetical protein"
                     /protein_id="WP_159395228.1"
                     /transl_table=11
                     /translation="MAGALDPERLALVGRAGFALEVGVQRVQALVSHLRHQRITEERLD
                     VQPDLRLIALLGGALDLMLLQPPVQQLPDREIGAVEGLSGLDRELGSSPREGLGVARAG
                     VAS"
     misc_feature    14484..14500
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.63"
                     /tool="antismash"
     misc_feature    14832..14846
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            15070..15255
                     /locus_tag="SMD11_RS05730"
                     /old_locus_tag="SMD11_1182"
     CDS             15070..15255
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS05730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_1182"
                     /product="hypothetical protein"
                     /protein_id="WP_087925393.1"
                     /transl_table=11
                     /translation="MRASKITNDLNAKESPVEVSANARHHSPGYTMERYGKRRPDAAKA
                     LAGRSAGRIGLARLAA"
     misc_feature    15326..15341
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     tRNA            complement(15401..15488)
                     /anticodon=(pos:complement(1331769..1331771),aa:Leu,
                     seq:gag)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="SMD11_RS05735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="SMD11_1183"
                     /product="tRNA-Leu"
     gene            complement(15401..15488)
                     /locus_tag="SMD11_RS05735"
                     /old_locus_tag="SMD11_1183"
     tRNA            complement(15714..15798)
                     /anticodon=(pos:complement(1332079..1332081),aa:Leu,
                     seq:gag)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="SMD11_RS05740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="SMD11_1184"
                     /product="tRNA-Leu"
     gene            complement(15714..15798)
                     /locus_tag="SMD11_RS05740"
                     /old_locus_tag="SMD11_1184"
     gene            15905..17236
                     /locus_tag="SMD11_RS05745"
                     /old_locus_tag="SMD11_1185"
     CDS             15905..17236
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612568.1"
                     /locus_tag="SMD11_RS05745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1185"
                     /product="DUF2254 domain-containing protein"
                     /protein_id="WP_087925394.1"
                     /transl_table=11
                     /translation="MGNDGHLGAPGGARWRPRALSPLREHLRDTFWFTPTVGLVGAAVA
                     AVGVLELDGLLIRTLQDDGDYGAVSTLIELADDTKTIITTVGSAMLTFIGVVFSISLVA
                     LQMASGQFSPRVVRLYVRSRITKCTFAVFLATFLFALLVQASYQGDTDPRTVETVPVFS
                     SVTCVVMVLVSLVLFVVYVNSTLRLMRVSHVIDRITRETFRMLEKAGGRADDESVVPGE
                     VTGEVAHRGRAGVLRDVHIARLVRVARRHGLVLRLIPRIGDFVVPGTPVLAVHGGPAPG
                     RRALRYTVSVGVERTFHQDLGFGLRQLSDIAQRALSPAVNDPTTAVQCLDRIVQILAAV
                     AGRPLGALRHYDRKGAVRLVQDLPGWEDLVDLGLAEIRGCAIGAPQVTRRLMAALDDLL
                     RLAPEDRHPPLVRHRTLLRQAVDLAVPEPADREFALLPDRQGIG"
     gene            complement(17256..18821)
                     /locus_tag="SMD11_RS05750"
                     /old_locus_tag="SMD11_1186"
     CDS             complement(17256..18821)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005482553.1"
                     /locus_tag="SMD11_RS05750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1186"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_087925395.1"
                     /sec_met_domain="Aldedh (E-value: 8.4e-97, bitscore: 323.2,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPSTDLTRTDLTLKPGTEWATAWQRCLAAAPEAFRGERVLNLWN
                     GTWRPDGRPLPATTPVDGTPIAGPPRLDAATAHRAVRASLDQHRAWRNVPLADRKARVR
                     ATLDALAGHRDLLALLLVWEIGKPWRAARADVDRAIDGVRWYAGEIDRMTEGRGPLPGP
                     VSNIASWNYPMSVLVHAMLVQVLAGNAVVAKTPTDGGLACLTLASALAAREGLPVTLVS
                     GSGGELSEALVRAPEIGCVSFVGGRDTGARVATAVADLGKRHILEQEGLNTWGVWDFTD
                     WEAFGSRIRKTFEYGKQRCTAYPRFVVQRSAFADFLAVYLPAVRALTLGHPLAVASPDD
                     DLPELDLGPLINAAKAKELTDQVAEAMNRGAIPLHRGELAAGRFLPGQDTSAYVAPVAL
                     LSPPPASPLHHAEPFGPVDTIVLVDTEAELLAAMNASNGALVATLSCDDRATYERLAPQ
                     IRAFKVGHGVPRSRGDREELFGGFGASWRGAFVGGELLVRAVTEGESAEERVPGNFPDY
                     HLMP"
     gene            19077..19934
                     /gene="fdhD"
                     /locus_tag="SMD11_RS05755"
                     /old_locus_tag="SMD11_1187"
     CDS             19077..19934
                     /GO_function="GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fdhD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128761.1"
                     /locus_tag="SMD11_RS05755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1187"
                     /product="formate dehydrogenase accessory sulfurtransferase
                     FdhD"
                     /protein_id="WP_087925396.1"
                     /transl_table=11
                     /translation="MGRVTSRRRVIRIRDGAVGTRPDTLVAEEPMEIRLNGKPLAITMR
                     TPGDDFALAAGFLVSEGVLATADELERIVYCAGATEDGSNTYNVVDVRLAPGVPLPDIA
                     LERNVYTTSSCGLCGKASLDAVRTTARHPVSDGPSPMRLTPELLATLPDRLREAQRVFE
                     TTGGLHGAALFSADGELLDVREDVGRHNAVDKIVGRALQQGLLPLSGTVLLVSGRASFE
                     LAQKAVMAGIPVLAAVSAPSSLAVDLAAETGLTLVGFLRGASMNVYAGEERVVLDGGAA
                     DDGA"
     gene            complement(19986..20402)
                     /locus_tag="SMD11_RS05760"
                     /old_locus_tag="SMD11_1188"
     CDS             complement(19986..20402)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942139.1"
                     /locus_tag="SMD11_RS05760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1188"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_234366351.1"
                     /transl_table=11
                     /translation="MTRIRALPSWQLNRASARGRRLVSEALAREGMRMPHHAVLSAVSD
                     LGPVAQAELGRTTGFDPKDMVGILNDLQAAGLITRAPDPADRRKNAISLTDEGGRRLVR
                     LAELGDEANEELLAGLTPGERERFLELLGKVAEG"
ORIGIN
        1 ccggtccggg gacgggccgc gatcgtcgcc gaactggtga ggttccacga gaggttcgcc
       61 gaagccccgg tacagcggcg gcactggttc aaccacatcg cgctgacccc gcggcccgac
      121 ggcagcgtcc gctccacggt gtacacgctc gtgctcacgg tccggccggg ccgccgggag
      181 ccggagatcg cgccgagctg tgtggtgcac gacgtcctgg agacggacgg ggacgggatc
      241 cgcacccggt cccggagcat cacccacgac cacctcggct gagccggccg gaccgccggg
      301 gccgccgcgc tacgccgacc gggcctgtac gaacgcttcc ccgccgtcca gttccggggc
      361 gcccgacagc acggcctgat gcagccgctg gagccgcggc gacggctcga cgcccagctc
      421 gcggcgcagc cgctcgcgca gctgccggaa ctcctggagc gcccgccagg ggctgcccga
      481 gcggcacagc gccgtcatca gctgcgcgca gaggttctcg tgcagggggt gccgggccac
      541 cagcgtgcgc aactcgccca gcagggccgc gtggtagccc aggcggaggt cggcctcgat
      601 gcgctcctcc agcgcctgca tacgggtctc ctccatgtac agggtctcca gccccaggac
      661 gcgtccgacc ggcacgtcga ccagcgccgg gccgcgccac agggcgagcg cgcgggtcag
      721 gtgcgccgag gccgaccggg cgtcgccggc gagcagcgcg tcgtgcccct ggccggccag
      781 gcggcggaac tgggaccagt cgcagctctc gggcgtgacg gcgacgcggt agccgccgaa
      841 ggccgtggcc aggacgtcct tcggggtgcg ggccggggac tccggcgcgt cgcgcagcgc
      901 gacggccatg cggcgccgca gctggaggat gtaggtctgg agggtggtcg ccgcgctgcg
      961 ggggatggcg tcgccccaca gctcctccat cagcgtcggc accggcacca cgcggccggc
     1021 ccacagggag agcagggcga ggatctggcg cggctttccc gcgctgggca cgatggagac
     1081 cccgttctcg tagaccgcga gttctcccag cacctcgatg tccatgagtg tcctccactc
     1141 ggttcacgat gtcgtccttc gacttgactc gaggctcgca ccgaggagcg gccaccgccc
     1201 agtgaggccg tcaccagagc aacggtgaga tcggcacgcc ccgtgtgagg aattcacagc
     1261 tccatttatt gctgccaacc aggggaccgt cacgggcgtc atgtgaggtt gactacagga
     1321 atcctcttca cgagtggttc tctgcttgac tgagcagttg gcccttcgga actccctcga
     1381 tcggcaggtc gcatggtggt gttatccaag ggtgagccgc ccccctggct cgccacaggc
     1441 atcgttctcg ccgtgcagtc cgcggtggcc gtgctgggtt tcctcaacct cctggcgtcg
     1501 cgccgtcctt ccgccggtca catctgcctc ttcctggccg ccttcgtcgc ggtgttcgtg
     1561 ctccagggga ttcactgcgc cccgcgggcc ggccggttcc gcgcccgcca cggacgccgg
     1621 acgctggcac tccaggccct gctgacctac gccccgctgt tcgccctggg cctcacctgg
     1681 gccggcatgc cgggcttcct ggccgggtcc gcgctgctca tcctcgaacc cccgctgtcc
     1741 gtcgccgcct tcgccgccgc cgcggtcctc accggcacct gcaccctgct ggccggccag
     1801 cagccgctgg gcgtcgccat aggagtgctg tcctgcgggg tgaacggcct gatggtgtac
     1861 ggggtcacgc gcatcgcctc ctggagcgcg gaggtgcggc gggcccgtga cgaggtcgcc
     1921 cggctggccg tggaaggcga acggctgcgg gtcgcccgcg atctgcacga cctgctgggc
     1981 tacagcctgt ccgccatcac cctcaagggg gagctggtgg cccggctggt cgacaaggac
     2041 cccgagcggg cgcacgggga gctgcgggag gtgctggaca tctcccggca ggccctcgcc
     2101 gacgtccgct gtgtcgccca cggctaccgt cagctctcgc tcaccgccga actggactcc
     2161 gccgcccgga tattgagcac cgcgggcatc acggtggagg tgcacgacga gcggctgccg
     2221 ctgcgcgagg aggccggcac ggtcctggcg accgtcgtcc gcgagggggt gaccaacatc
     2281 ctgcgccaca gcgccgcgca gaactgccgc atcaccgtct cccgcaccgc cggcacgctc
     2341 gcgctcgaca tggcggggga cggcatcccc ggcgacaccg gggagaggat ggcgcgccgt
     2401 tcgggcggcg gcctggacaa tctcgcccgg cggctggaag ggatcggcgg gacgttccgc
     2461 gcgtgcgccg gcgaggacgg gtggttccgg atcttcgccg agtgcccggc cgacgcggcc
     2521 gggccgccgc gggacgtcag cggatccagc ccttctcctt ggcgatccgg acggcgtcca
     2581 gctgattccg tgcggtgagt ttggtgacgg cggaggtcag gtaattgcgc accgttcccg
     2641 tggagaggtg catctcccgg gcggtctccc gcgcggagtt gccgtcggcg gcccgcttga
     2701 ggacatcggt ctcacgccgg gtgagcgggc tgtccgtggg gcggccggcg atcgggcagt
     2761 cctcggcctc ccaggcggtg ggcgggatcc gcgaatcgat cacccgccgc cccgagtgca
     2821 ccaggcggat ggcggtggcg agctcggcgg gcggggcgtt cttgggcagg aacccccgga
     2881 cgtgggcgtc gatcgcccgg cggaccgtac cccgctgctc cagcgcggtc aggatgatca
     2941 cccggcactc gggagcctgc tcccacagca gcccggccgc gtccaggccg ttgacgccgg
     3001 gcaggtcgat gtcgaggatc gccacatcgg gccggaactt gatcacggac ggcaggatgc
     3061 cccggccgtc cgcgacctcc gcgaccacac ggaagtcggg ctccagttcg aggagcgcca
     3121 ccagcgcccc ccggaccatg tgcatgtcct cggccagcaa gatccggatc accggtcgtc
     3181 ccccgtcaga ctttcgccgg tgacccgtat ccccaacagg ctgacccggc aggtgacttc
     3241 acctcaagcc tacgtcgcca ccgccaggag acccgtaact gttttcgcgc gtcctccctc
     3301 tgtccgcttc cgcgccggcg gtccgccggc cgtccgatcg atccgtcctc gatccgccgg
     3361 tacgagcatg gcggcccggt gttccgatcg gtcaggaggc acggtgtccc aggtacggcg
     3421 gaaagggtcg gcgggcaggc tcgccgaggt ggccgacggc gtcttcgcct atgtgcagcc
     3481 ggacggcggg tggtgcctga acaacgcggc gctggtggtg tcccgggggc actccgccct
     3541 ggtggacacg gcggcgaccg aggcccgcgc ccgcgcgctg cggacggcgg cgctcggcgt
     3601 ctgcccggcg ccgccgcggg tcctggtcgg cacccactcc cacggggacc acaccttcgg
     3661 caacttcctc ttccccgagg ccctggtcat cggccacgag cgggcccgcg gcgagatggc
     3721 ggaagcgggc ctccatctga cggggctctg gcccgaggtg gagtggggcg agctcaccct
     3781 caccctgccc gaggtcacct accgcgaccg gctgaccctc catgtgggcg acgtggaggc
     3841 cgagttgatc cacctcggtc ccgcccacac cacccgcgac accgtcgtcc ggctgcccgg
     3901 tcaagcgggt gctcatcacc ggggacctgg tgatgagcgg cgtcacgccc ttctgcccga
     3961 tggggtcggt caccgggacg ctcgacgcgg tggcccggct gcgcgccctc gacgcgcgca
     4021 ccgtcatcac cggccacggg cccgtggccg gccccgaggt cttcgacgtc accgagggct
     4081 acctacggtg ggtccaggag ctggcccgcg agggactcgc cgcggggctc accccactgg
     4141 aggccgcgcg ggcggcgggc cccggcccgt acgcgcacct gatcgactcc gaacggctgg
     4201 tgcccaacct ccaccgggcc tacgcggagg agcgcggcgc cgcgcccggc gtcccgctcg
     4261 acatcggcga gttgttccgg gagatggtgg agtttcacgg tgggctgccg acctgccggg
     4321 cctgagcgtc ccagacggtg aacgtccccc ggtggtagag caccggcggc cgcggatagg
     4381 actcggcgtg ctccacccgt ccgatgaaga tccagtggtc gccggcctcc accgtccgca
     4441 ccaccacgca ctcggcgtgc gccagggcga cgtccaccag cacgggcgcg ccccgggcgt
     4501 gggcggaggg cacccactcg acaccggcga acttgtgctc ggagcggtcg gtgaagaccc
     4561 gcgccgcgtc ctgccccccg tcggcgagga cgttgaccac gaaggccccc gagtgccgca
     4621 gcgccgccag ggtccgcgcg ttccggtgca cgcacaccag gagcaacggc ggttccacgg
     4681 agaccgccga caccgcgttg caggtcaggc cccgcggtct gccgttcgcg tccgtcgcgg
     4741 tgacgacggt gaccgccgtc gggaaggatc cgaacaacgc gcgaaaccgc gccgcgtcca
     4801 ctgccatgcc gctcccgcct ccggccggtc ttctccgagt gatccggccg ttcacgctcg
     4861 ccgaccggtc tggagggcgg gtggaccggc ggtggagggt gcggcgggac gggccgggtc
     4921 cacagagcat tttccacggc cggatcgtca agggctgatg atcgcgtcgc ggcgtagccg
     4981 ctgacccgcc gtctccctca cgggcccgcc ccggaatcga ggcgggccca gccgcaccgg
     5041 ccccaccgcc ggctgtcgcc tgacaggccc cgcggcggga ccagcgctta cgaccgtcag
     5101 tacgtcagga ccacacagcc caggtttccg gcctggcccg gcttgccctt gaggcgtccc
     5161 aaggtccccg gaggggcggg cagggggtcg aagctggcac cgccaccctc gccaccgtcc
     5221 ccaccgcggc ccgcgacggc cggacaggtc ggcggcacgg cgtacggtcg cgcgcccgcg
     5281 cctcccgcac cgcccgccac cctggtcccg gccaggccgg aggccggaac ggcacccggc
     5341 ctcgtcgtgg gctcaccgac gcagcggccc ttgccgagac cgctggtggc gccggagccc
     5401 gtacccccgg ctcccggccc gacatccagc tgcccccgga taccggcggc accgccggca
     5461 ccgcgcggag ccccggccgt ctgctgcccg ccggggaagt ggaccgtgga cccgcccgtg
     5521 tccttgccgg cttcgccgtc ggtcgggttg gaccagttca gagtgccgcc cgcgccaccc
     5581 gcaccgcccc cggcgacgtc gatcgacagg gtctcaccgg gggtgacgtt cagggtgcac
     5641 tggaagtagc cgcctgcggc gccgcccgca ccgcctccgc cgccgagcat gatcgcgctg
     5701 ttctccgtgg ggaagaccac caggccgccg cccccgcccc cgccgccgcc cccggggccc
     5761 acggccgtca tcacgatctt cgtgaccccg tccgggaccg tcatccgcgt cgtcttcgcc
     5821 tcactgaacg tcagggtggt cttcccaccc gcaggagccg cgaacgcctc ccccaccggc
     5881 aggaagcccc ccagcactcc ggacgccacc gccaacgcca cggcggtccg ccgccgtaac
     5941 ccacgtctta cgaccatctc agctctcctt gatagacgct gaaaacacgg ctgtaccgac
     6001 cgcaatggca gcacgccggg agtcgatcac cagacgggca ccgccgcgtc atggaaatga
     6061 ggcggaccga cgccatccag tgaacggttt ctcgcctgcc ctgcccattt cttccagtgc
     6121 cacaacggtc actcagcgcc cttacggtgg caggggttac tcaggaaaat cactactcat
     6181 tccgcgagca cgccgggcat ggtcacctgc cggacgggta cgcaagatca ccgtcgaagg
     6241 cggcgacgcc gggcccgcgt ctcctgtggc cgaggttcag ggcgagcccg cttccgtggg
     6301 tcacgcggag cgtcatcaga ccggaaaaac agaaaaaccc cagatgaact ggggttcctg
     6361 ctggtgtccg agggggactt ggactctcct ctcgggcacc aacccgtcag gtctctgacc
     6421 tgcggaaaca ccagtctgaa gggtctatcc gcgccctcat gtcacctggg ttttcctggg
     6481 cttttccggg tgctcccggc cgctactggt cacgcgctgg tcatggcggg gggacgaagg
     6541 ccaagcagcc acccaaggtg cgccagtgtg cgattgtgtg gcgatgaagt ggcgaagtgt
     6601 ggcctgcgat caagcagcgt accgagggat caacggcctt cggtgcgctg tctgactaag
     6661 acgtcgtttc ttatggcgtg atcgttcgtt gagccgtgca tggcggatct cgtggagcga
     6721 ctggtgccgg acgagttgtg ggtgctgttc cggcgggtgg tgccaccgac tgaggtgata
     6781 cgtccgcagg gcggtggccg gcgtcgggcc ggtgaccgcg aagccctggc ggcgatcatc
     6841 ttcgtggcga cgtcgggctg cacctggcgg cagctgccgc cggtgttcgg cccggcctgg
     6901 caaacggtct accgacgctt cgcccagtgg agccgggacc gggtctgggc ccggctctac
     6961 cgtgtcatcc ttgacgaact cggagcgcgg ggcgagctgg actggtcgcg gtgcgcgatc
     7021 gactcggtca gcctgcgggc tgcaaagggg ggcctttgac gggaccgaat ccgaccgacc
     7081 gcggcaagct gggatcgaag attcatctga tctgcgaccg gaacggactg ccgctgtcct
     7141 tgggcatctc cggcgcgaac atgcatgaca gtctgggcct ggagccgctt gtgcgcggca
     7201 tcccgccgat ccggtcccgc cgtggtcccc ggcgtcggcg gccggcgaag ctgcatgcag
     7261 acaagggcta tgactacgac cacctgcgcc gatggcttcg caagcgcggt atccgccatc
     7321 gcattacccg caagggtgtc gagtcctcgc agcggctggg ccggcatcgg tgggtggtcg
     7381 agagaaccgt gtcctggctg gccggctgcc gacgcctcca ccgccgctac gaacgcaagg
     7441 ccgaacactt cctcgccttc gtcggcatag ccgcagccct catcggctac cgccgactgg
     7501 cggctctgct cacggcctga gccggttctg ctgtacgtcg aagcagatca ggcccatgga
     7561 ctccgcgacg gccgccgcgt aggccgacgc ctcctcggcc atgctccacc gcgtggggaa
     7621 gtagatcagc ggaccactgg cctcgccgat cagcggcccg gttgaccagg gcgaggtgtc
     7681 ctcctcgtcc tcagtgaggt cacaccaccg ctcaagcaac gcggccacgt aagccgcgat
     7741 gcgctcggac ggaggctctt ccacctcgct gtcgatgtag cggtcgtaca ggtcgttgaa
     7801 gacccggccc gcggtcttgt catccgccgg cctctcgcct tcccagacag caaggtcgta
     7861 gctcatgtca ggaggctctc atgccgctct gacagccaaa agaaacgacg tctaagcgca
     7921 ctgcccgccc gttcgcaggg actgccagtc gtcgttgtct cccgggttcg gcggcctctg
     7981 cggttcgctg gcagtgtcga accatgtggc gtaggcggtc tcggtgcaac tgctagacgc
     8041 ggtgcgaagc aggatggggc tcgcgggctg gaaaccctcc ccggggttga cagagccact
     8101 tccgctggca gcgcatgtga cctcgtctga actgaccacg ttgcaggtgc ctaccttcac
     8161 gtcggtctcg ccggtgacct tcctcttgac caggctgaag gaagaaccca cgttgacgaa
     8221 ctccccgtcg ttactggcgc ccatcttgaa tcgccacgta gtgctgtagc tgcacgggct
     8281 tgggtctgtc cctggacctg gattggggtc gcagaggaca tagggcgtcc atgagacatt
     8341 ggagcccggc gacaccgttt gggcggcgac cccgaacccc cagttgccgg tggccgcaaa
     8401 cgacgttccc tgcgagagca tcagggccgc tgcgctcaga accgcgactg cggcggacct
     8461 acacctggtc gatctcctct tccgatccac gatcgtcccc cttgctgggt ggctccctgc
     8521 ttctgtgatt gacagaagag cgcggtccgt cagcagggga tagacctgct gcaagtgctt
     8581 cacccgattg ggcgcgctgc actgcatcca gggccacttc aggcccacta acatccagga
     8641 acggacgaca gcgcaacgcc ttgggcgcca cgctcggaga agcgcggagg ccagggtcgt
     8701 cctacggtcg aaccgtggac ttccggatca cagccgggga agaacagcta ctcttcgtga
     8761 tcgtcgctca cctggactcc ggcagcgcac cgacggtcga ggagctgtcc gccgaagcgg
     8821 ggcacgacgc ccaccctgac gttgcctcgc tacgtgacaa gggatgggtc ctcatcgaca
     8881 ggcagaacac tgtcatcgcg ctgtcaccga tggccgtcca ggccgtgagg aacctgcgct
     8941 tcgggcagcg agtcggggca tagcgaagcc ccgcccggcg taggccggac ggggcggttg
     9001 ggggggctca gcgggcctca gggcccgtgt cgtcaccgat cttcatgggg cagtagtgcc
     9061 ggacggggac gatgaccccg accccgctgg gccgctctac gtaccggtcc agctcgaagc
     9121 acccacatgt ggatgcgcgc gataaggtca cgcatgcgtc tcagctcctg aatagctggt
     9181 ggcgtcagaa ccccaacggt cgttggcccg actgtcgggg tttttctgtg tcctgacgct
     9241 ggcggtcttg tataggctca tccaccctta ctcagattca gtcaggcatg accagccaac
     9301 tactctggct gcatgacagc gagcaagatc aatcaccggg ccccggagcc gccctaccgg
     9361 cagatcgctg cggatctcat tcgggacatc gaggctggct cgctggaagt gggcagccct
     9421 ctgccatccg aaaacgagct ggtggtgagg tgcggcgtgg cccggaacac ggtgcggaac
     9481 gtcgtggctc acctccggga gcgggggtac gtctacacgg tcccgaagcg cgggacctat
     9541 gtgcgtcagc gtgagcagcc ctaagaagaa cggccccgcc tgtgcctcct tgcgggaggc
     9601 gcaggcgggg ccggccgggg tagttctcag gaaccagttg gccgcggtac ggacgcagtc
     9661 cgcaattccg agagccgtcg ctggtagagg ggtcccgtgg agaacgacac ctctgcgggt
     9721 gtgggcgcgg cctcctcgat gaggtggtgc gccaacgctt tgagatgcgc tgaccaggcc
     9781 actacgtgtt gctgggcagg gcgcccgcac tcctgaggct ccccgggaag gcagaggggg
     9841 agatcggtgc ggctgagctt gttggcggcg tgccgcacgt atcgggcgac ggtgagccat
     9901 tcctcgtccg aacgctcgac ggcacggcca tggctctgcc cgagccaggc accgaagtcg
     9961 tctccgtgat caaccatggc gtgctcctac tggatcagct tcacgcgggt gcgccgatcg
    10021 tagctgtggc cagctggctg tcggcctccc tcgggtcaca gtgcgccaca gaggggacac
    10081 aggggccgca ggggccgcag ctcgggagga actgcggcgg ggtacagctt tgggctggct
    10141 tcagcccgtg agctgccgcg atctctgcgc gagcatcgat cgtccgaggg ctgttccaca
    10201 cctcggtaag cggggtcgtg cgcacgttgc ccagggtgat gaagcgtccc agcacgcacg
    10261 gccacactgc cccgtcgggg ccgatggcca cctgtccgag tgcgcagtgt ccgcagagat
    10321 cgttgactga aggggtggct cccttgctgg cccgcccgaa ggctcgtgtc ctgtcaccgc
    10381 cgacgtggtc aaccccgatc tcctgaaggt cggtgaccgc ctcgcggacg cgctgttgtg
    10441 tgctcaccgc gacgacgccc ccgcgaatgg ggatgccgag ctccacggcc ttgcggatgt
    10501 tcgcccgggt catcttgtgc gcgccgcgaa ggttcgtcac tttgtcgtgc tcggttgcat
    10561 cgtcggagta gtacgacgtc gccagcttga cgccgtagga cttgaacgcc tcccagagcg
    10621 ggtctcggat gacggtcatg ttggaaaaca cttcgatgcc gagtcccgcg ccgtgcgcgt
    10681 gaccgatcag cctggccagg tgggggtaca gggtcggctc cccgccgatg aactgaacgt
    10741 cgcgtccgcc gattgcggcg aactcatcga tgacgcgctg ccagtccgaa acggtcatga
    10801 tgccgtgagt ccctttggga cccgaatcgg catagcagtg gtcacaggac tcgttgcaga
    10861 atcccgtcac ttcgagccag gcgaatccga gcttccgcgg gctcggacac gtgcgtaacc
    10921 tgggatcgcc catgggtgat cctctcctct gtctgggggt tactgggtgt tcggcccggc
    10981 ggggaaggtg gcacttcccc gccggtaccg tgtgcgcgga gctccgactt agttggcgag
    11041 caccgcgcct accaggtcga tggcctcggg ctgctcgctc tggtcgtcgg gaacggtggg
    11101 ctcgttgtcg gcggtttcgg tgtcgcttcc gatgacctcg gggtcggcgg tctcggtgtt
    11161 ggggttggtg gtcgcgggca ttccgcggcc tcctctctct cgtcaggtcc cggcccggct
    11221 gggcgcgggg ttgctcgtcc gcttccctac gtcgggacga gcacccgtca tcgggtgggc
    11281 caccggctga tggagatgcc gacgccccgg gacgtccccg ccgatggcgg aagtgtgagg
    11341 cttactggcc ggtgggctta cccaaggagg gatcacggcg cagttcaaga gctgcggccc
    11401 tgtcgcggcg cggttccttc cactcgtcca accggtcgca cagccacggc tcgctgacct
    11461 cgtattgcgt ggccagcctg ttcatggact cgccggcgcg gtaccgcttg atgatgtccg
    11521 cctgagcggc tcgggctcgt tcgcgcgcct gtcgcttctg cgtcgtcgtt ctcgacatgg
    11581 ctacttcccc cacttggtgg ggtcctcgtt gttcccgtca ccattgttga tgtcgtgctc
    11641 gataccgtcg ccctcttcct ggtcggccgg atgtccggag ccacttgccc aaccacccat
    11701 aggggcatca ccctcttcgt agttccgtct ggaaccccgt ccgggcgctg gacgcgacat
    11761 ctgacgtctg gacgggggct tggagcccgc ccctgtgcca gtagggggga ggaagggcaa
    11821 cccataggaa tccgatgggt ccatccggca gaggggcagg cggtctaggt gcagtgcgcc
    11881 tcgtcgaagt ggctgacgat ctgctcctga atgcgctttt ccgccacgcg gtcgccaagc
    11941 ccgcgtgccg cggtgagggc gatgcccagc tcgatgcatt ccgagcaggg cggcttctcc
    12001 ggctcacgcg gcatggacgg gcgtccgctg gtgtgtgcta cgggaaccac cggcagcccg
    12061 aagatccgcc gaagcatcag cacaaccggc cccttctgcg taccggctcc agcgccttta
    12121 tcgacgtgtc acccaccagc gggtacggaa tgggctcgcc ctccggccgc tggatgatgc
    12181 cgccgcttcc ggtcgtaaac gcacgtctcg tcgccgtgcc ggccccgttc gtcggcgctt
    12241 ccgtcacgcc tgcctgccgc atttcccttg cgctggccgg cctgagtgcc tccgggtcgg
    12301 cgtcccactc ccggccgcct ccgggcgctc gcagttgcac gtacgggccc accttgtcca
    12361 tgcgctgccc caagcacccc tttcgcgtgt ccaccaccca aacggggggt tcctgcgctg
    12421 cgttcatcat ctgttcgagc ctccgcgtat cccgcgtcgg acggtcgcgt actgcctcag
    12481 ccatcccggc gcttcagcca actgcaccgc tcccagcgag ctgcttccgt gggttgtccg
    12541 acctgcgcac tacgcaaccg cacagctacg cacggcggta ctgtgaagag acggccagag
    12601 catgaaagcc atgaacgcaa cgcaatctgt ggggagtcag aggcatggcg acctccgcgc
    12661 gtacacccaa tgagggcctg ggacggctgc ttgtgcaggc caaatggtcc cgctcgcagt
    12721 tcgcgctgat catcaaccgc atgggcgctg aggcagggtt gacgttgcac tacgaccaat
    12781 cggctgtttc acactggatt gggggaactg tccccaagcc cccggtcaga cggctgatcg
    12841 ttgaagctct ctcgcgcaag ctacgtcgta ctgtgactca cgcggaggct ggattgccgc
    12901 gcgccgctga ggacgaggtg ccggctggcc ttgacactgt ggaagaaatc gtcgacctcg
    12961 ggagggccga catggatcca tctcgccgag ggctcgtagc cacagccggc ttgttctccg
    13021 cggctttagt ggtgccgtcg ttcgcggggc ctgcgcgcgc tgtggaagcc ctccctgcgg
    13081 tcccagggaa gcagactgtg aggatcggcg ctgggcaggt cgcggctgtt cggaagatga
    13141 ctgacaaaat cgcggatatt ctggacgagc ttggcggggc acacgcaagg ccaatggcgg
    13201 cggcattcct cgtcaacacg gtggttccgt ggcttcgagc cgaagccaca gatgcagtga
    13261 ggaaagactt ctgggcagcg gcctcggacc tcgtctatct gactggctgg atggccatgt
    13321 acgagcggga ccacggaact gcccagaact actacgtcaa ggcattgaag ctggcgaacc
    13381 gtgcagagga tcacgtgacg tactgccgca ccctacgcgg tatgagcctt caggcttcca
    13441 accttgggta cgggccccta gccctaaagt ttgctgattc ggcggctgaa gccgccccga
    13501 aaactgggcc gcgacttcag gccttcctcg cagggcaaca ggcccatgcc actgcgatgg
    13561 tgggcgacca ccgccgcgcg cggcggctgc tggccgccac tgaaaccgcc ctgatgaagg
    13621 ctgacaatcg gcgcgagtca atcggtggat acgaccagtc ttcttacgcc tttcacgtct
    13681 ctcatgtgct gtacgagagt aaggatctac caggctcgat caaagcgctg caacaggccc
    13741 taaaggtaca acctccccaa gagcggcaag gtcgggttca tttctacgga gtgctcgcac
    13801 aacgccagct tgagtacggc cacctcgaag cagcctgcga atcgtggaca cgtttcctgg
    13861 aggactatga acatgtctca tctgccaggg gggacgcgca ctttgacacg atgcggctcc
    13921 ggctgaagcc gttcaagagt tcccaggctg tgcgaaggat gtctgcacgc attgctgaca
    13981 tcgccctgct caaggcgtga cttgatgtca cccggcttct tggctgcccc tcaagcaggt
    14041 gaacgcacat tcaaggcggg tcggcactcg gtgcggaatc ctgcgcgaca gcaggggccc
    14101 tgttagctgg ccacccccgc gcgggcaact ccgagaccct ccctcgggga gctcccaagc
    14161 tcccgatcaa ggccgctgag accctctacc gccccgatct cacggtcggg gagctgctgg
    14221 accggtggct gaagaagcat caggtcgagg gcaccaccaa gcaaggctat gagccgaaga
    14281 tcaggctgca catcaagcct ctcctcggtg atgcgctggt ggcgcaggtg actgacgagg
    14341 gcctggacgc gctgtacgcc tacctccaga gcgaaccccg ccctaccaac aagggcaagc
    14401 cgctcggggt caagggcgcc cgccatgtcc acaacatcct aagtgctgcc ttcgactcgg
    14461 tcacggggcc gcggaagctg ctccagcaca acccttgcaa ggaggctcac cctccgacgg
    14521 agcggatgat ccgagcagcg gaaccggatt tccccacact gtccgacagc gagacgagca
    14581 agtttctcga cgacatttgg acgccatgcg ggaactcgaa gtgtgacggg ggcctgacgc
    14641 accactgcct ccgcgatgcc ccgctgtgga cgtcgtacgc cgtcacggga tgctgccgcg
    14701 gcgaaatcct ggggtggaag tggtcactca tcaactggga agagtgctcc atcgagctgg
    14761 cgtgggtcgt ggtcgaggaa ggcaacacct accgactgcg gaagctgacc aaggacggcg
    14821 acaagggcgc gatcatctac gtggatcaag ccttcatgag ggtgctgcgg tggcagtggg
    14881 agcgccagca gtacgagaag gagagactcg gtgacctctg ggtcgatcac gacctcgtgt
    14941 acgcccggga cggcttcaag ctgtaccggg gcgaggccgg cggcccccca ggaccccgag
    15001 aaggtaacgg cgcggtggcg cacccttcga aaccggctcc acctgcccga ggacttccgg
    15061 ctgcacgact tgcgggcaag caagatcacg aacgacctca acgccaagga aagcccggtc
    15121 gaggtctccg cgaacgcccg gcaccacagc cccggctaca cgatggaacg ctacggcaag
    15181 cgtcgaccgg acgcggcgaa ggcgctggcc ggacgtagcg ccggccggat cggcctggct
    15241 cgcctcgcgg cctgatccaa gattcccggc cggtcgtctc gtggttggtc acgctgccgg
    15301 tcgcagaaaa acccgaatcc tactggtcac gcactggtca cgcggacgtg cgatccagcc
    15361 cggaaaaaca gaaaaacccc aggtcaactg gggttcctgc tggtgtccga ggggggactt
    15421 gaacccccac gcccgataaa gggcactagc acctcaagct agcgcgtctg ccattccgcc
    15481 acccggacca ggtgtctgac tctgcggggc gttccccgcg gcgacatgga caactctatc
    15541 aagggttcgg agcaccgttg accagggctt tcgtccggga tcacggcccg cgcaggggcc
    15601 ggtcggcaag atcgccgggc gcccggcccg tcaccgcgcc gtaggtcacg cggccggccg
    15661 cgccatcacc cggaaaagca gaaaaacccc acgtgaagtg gggtttcatc ttgtgtccga
    15721 ggggggactt gaacccccac gcccgataaa gggcactagc acctcaagct agcgcgtctg
    15781 ccattccgcc acccggacca ggtgtttgtc tcagcggggc gttccccgcg gcgacatgga
    15841 caacaatacc aaggtttcgg agtgcctttc acctgggtat ctgcgccgga cataaggtct
    15901 tcttatgggc aatgacggac atctcggagc gccgggtggg gcgcggtggc ggccgcgggc
    15961 gttgtcgccg ctgcgggagc acctgcggga caccttctgg ttcacgccga ccgtggggct
    16021 ggtgggggcc gcggtggcgg cggtgggggt gctggagctc gacgggttgt tgatccggac
    16081 gcttcaggac gacggggact acggcgcggt ctccacgctg atcgagctcg cggacgacac
    16141 caagacgatc atcacgaccg tgggctcggc gatgctgacc ttcatcggtg tggtgttctc
    16201 gatctcgctc gtcgcgctcc agatggccag cgggcagttc tcaccgcgcg tggtgcggct
    16261 ctacgtgcgc agccggatca ccaagtgcac gttcgccgtc ttcctggcga ccttcctgtt
    16321 cgcgctgctg gtgcaggcct cctaccaggg ggacaccgac ccgcggaccg tcgagacggt
    16381 gccggtgttc tccagcgtga cctgtgtggt catggtgctg gtgagcctgg tgctgttcgt
    16441 cgtgtatgtg aactccacgc tgcgcctgat gcgggtcagc cacgtcatcg accggatcac
    16501 ccgcgagacc ttccggatgc tggagaaagc cggagggcgg gcggacgacg agtccgtcgt
    16561 gccgggtgag gtcacgggcg aggtggcgca ccgggggcgg gccggggtgc tgcgcgacgt
    16621 gcacatcgcc cggctggtgc gcgtcgcgcg gcggcacggc ctggtgctgc ggctgatccc
    16681 gcgcatcggg gacttcgtcg tccccggcac gcccgtgctg gccgtgcacg gcgggcccgc
    16741 gcccggccgg cgggccctgc ggtacaccgt ctccgtcggg gtggagcgga ccttccacca
    16801 ggacctgggc ttcggcctgc ggcagctctc cgacatcgcc cagcgggccc tctcccccgc
    16861 cgtcaacgat ccgacgaccg ccgtgcagtg cctggaccgc atcgtgcaga tcctcgcggc
    16921 ggtcgccggc cggccgctcg gcgccctgcg ccactacgac cggaagggcg cggtccggct
    16981 ggtgcaggac ctgcccggct gggaggacct cgtcgacctc ggcctcgccg agatccgcgg
    17041 ctgcgccatc ggcgccccgc aggtgacccg ccggctcatg gccgccctcg acgacctgct
    17101 gcggctcgcc cccgaagacc ggcacccacc gctcgtacgg caccggacgc tcctgcggca
    17161 ggccgtcgac ctcgcggtgc ccgagcccgc cgaccgggag ttcgccctgc ttcccgaccg
    17221 gcagggcatc ggatgaggcc ccggcccccg gtctcctacg gcatcaagtg gtagtccggg
    17281 aagttccccg gcacccgctc ctccgccgac tccccctccg tcaccgccct caccagcagc
    17341 tccccgccca cgaacgcccc gcgccacgac gccccgaagc ctccgaacag ctcctcccgg
    17401 tccccgcgcg agcgcggtac gccgtggccc accttgaacg cccggatctg cggcgccagg
    17461 cgttcgtacg tcgcccggtc atcacaggac agcgtggcca ccagcgcgcc gttgctcgcg
    17521 ttcatcgccg cgagcagctc ggcctccgtg tccaccagga cgatcgtgtc caccgggccg
    17581 aacggctccg cgtggtgcag cggtgacgcc ggcggcgggc tgaggagcgc gaccggtgcc
    17641 acgtacgcgc tcgtgtcctg gcccggcagg aagcggccgg cggcgagctc gccgcggtgc
    17701 aggggtatcg cgccgcggtt catcgcctcc gccacctggt ccgtcagctc cttggccttg
    17761 gccgcgttga tcagcgggcc gaggtccagc tcggggaggt cgtcgtccgg tgacgccacg
    17821 gccagcgggt gccccagggt cagcgcccgc acggccggca ggtagacggc caggaagtcc
    17881 gcgaaggccg accgctgcac cacgaaccgc gggtacgccg tgcagcgctg cttcccgtac
    17941 tcgaaggtct tgcggatccg cgagccgaac gcctcccagt ccgtgaagtc ccacacgccc
    18001 caggtattaa ggccctcctg ctccaggatg tggcgcttgc ccaggtccgc gacggccgtg
    18061 gcgacccgcg cgccggtgtc ccggccgccc acgaaggaca cacagccgat ctcgggggcg
    18121 cgtaccaggg cctcggagag ctcgccgcca ctgccgctga cgagcgtcac cggcagcccc
    18181 tcgcgggcgg cgagggcgct cgccagggtc aggcaggcca ggccgccgtc cgtcggcgtc
    18241 ttcgccacga cggcgttgcc ggccagcacc tggacgagca tggcgtggac gagcacgctc
    18301 atcgggtagt tccagctggc gatgttgctg accgggccgg gcagcggccc gcggccctcc
    18361 gtcatgcggt cgatctcccc ggcgtaccag cgcacgccgt cgatcgcccg gtccacgtcc
    18421 gcccgcgccg cccgccaggg cttgccgatc tcccagacga ggaggagggc gaggaggtcg
    18481 cggtgcccgg cgagcgcgtc gagggtggcg cgcacgcgcg ccttgcggtc ggcgagcggt
    18541 acgttccgcc aggcgcggtg ctggtccagg gaggcccgta cggcccggtg ggcggtggcg
    18601 gcgtcgaggc ggggcgggcc cgcgatcggg gtgccgtcga ccggggtcgt ggcggggagc
    18661 gggcggccgt cgggccgcca ggtgccgttc cagaggttga ggacgcgctc gccccggaac
    18721 gcctcgggtg ccgcggcgag gcagcgctgc caggccgtgg cccattcggt gccgggcttg
    18781 agggtgaggt cggtgcgggt gaggtcggtg ctcggtgcca tcgcaggtct ccgctctcgg
    18841 tgcacggtcg aggcaaggag gtggcgcgcg gtgctcacac gtacgactgt cgcgtactgc
    18901 taccgaacag tagccagggt gcggggccgc cggaggggtg cccggctgcg atgaggccca
    18961 cgtcacgtga gaccgtttgc gggcagaccg tccgagggcc cgagcggtcc gccccggccg
    19021 ttcgctccgc ttcgttcgct ttgtccgctc tcctcaccac cacgggactg atcgccatgg
    19081 gacgggtcac ctcacgacgc cgcgtcatcc gcatccgcga cggagcggtc ggcacgcgcc
    19141 cggacaccct cgtggccgag gagccgatgg agatccggct caacggcaag ccgctcgcca
    19201 tcaccatgcg caccccgggc gacgacttcg cgctcgcggc cggcttcctg gtcagcgagg
    19261 gcgtcctggc caccgccgac gagctcgaac gcatcgtcta ctgcgcgggc gccacggagg
    19321 acggctcgaa cacgtacaac gtcgtcgacg tgcgcctcgc ccccggcgtg ccgctccccg
    19381 acatcgcgct cgaacgcaac gtctacacca cctcgtcctg cggcctgtgc ggcaaggcca
    19441 gcctggacgc cgtacggacc accgcgcggc acccggtctc cgacggcccg tcaccgatgc
    19501 ggctcacccc ggaactgctg gccaccctcc ccgaccggct gcgggaggcg cagcgcgtct
    19561 tcgagaccac gggcgggctg cacggcgccg cgctgttctc ggcggacggc gagctgctgg
    19621 acgtccgcga ggacgtgggg cggcacaacg cggtcgacaa gatcgtcgga cgggccctgc
    19681 aacaggggct gctgccgctg tcgggcacgg tgctgctggt gtcggggcgc gcgtcgttcg
    19741 agctggcgca gaaggccgtg atggccggga tcccggtgct cgcggcggtg tcggcgccgt
    19801 cctcgctggc ggtggacctg gcggcggaga cggggctgac gctggtgggg ttcctgcgcg
    19861 gcgcgtcgat gaacgtctac gcgggggagg agcgggtggt gctggacggg ggcgcggcgg
    19921 acgacggcgc ctagtcccgg ccaccccggc cgctcaggcc cggggcggcc gccccggccc
    19981 ggccctcacc cctccgccac cttccccagc agctccagga accgctcccg ctcccccggc
    20041 gtcagccccg ccagcagttc ctcgttcgcc tcgtccccca gctccgccag ccgtaccagc
    20101 cgccgcccgc cctcgtccgt gagcgagatg gcgttcttgc gccggtccgc cgggtccggc
    20161 gcgcgcgtga tcagccccgc ggcctggagg tcgttgagga tgccgaccat gtccttgggg
    20221 tcgaagccgg tcgtacggcc cagctcggcc tgggcgacgg ggcccaggtc cgacacggcc
    20281 gacagcaccg cgtggtgcgg catccgcatg ccctcccggg cgagggcctc gctcaccagg
    20341 cggcggccgc gcgcggaggc gcggttgagc tgccagctgg ggagggcgcg gatccgggtc
    20401 agcgccggtg cgtcccggtc ggccccggcc ggggaagcgg ggtcggcccc ggcctgggaa
    20461 gcggggtcgg ccccggcctg ggaagcgggg tcggccccgg cctgggaagt acgggcaact
    20521 gcggcctggg aagtacgggc agccccggtc cgggaaacgg gtgcggcccc ggcggtctcg
    20581 ttctccatgc cccgacccta cccacaaaac cattggacct cccaatgaaa ttcacatacc
    20641 gttgggacca ccaacgacat ctgggaggtg cgcgtgcgtc gcgtccggta tttcgagaac
    20701 ggcggccccg aggtcctgcg ggtcgaggag gccgacgtgc ccgcccccgg ccccggcgaa
    20761 ctgctgctgc gcaccgaggc cgtgggcgtg accctgccgg ccgtccggaa ggtgcgggag
    20821 ggcgggctgc cgctgcccgc cggcctcggg ggcgaggtgg ccggccggat cgtcgcggtc
    20881 gggccggacg tgacgggctt cgcggccggc gaccgcgtca cggggctgtg ctt
//
