LOCUS       NZ_CP021744            26655 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces albireticuli strain MDJK11 chromosome, complete genome.
ACCESSION   NZ_CP021744
VERSION     NZ_CP021744.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces albireticuli
  ORGANISM  Streptomyces albireticuli
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8144417)
  AUTHORS   Wang,Y., Du,B., Ding,Y., Liu,H., Hou,Q., Liu,K., Yao,L. and Wang,C.
  TITLE     Streptomyces albireticuli Genome sequencing and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8144417)
  AUTHORS   Wang,Y., Du,B., Ding,Y., Liu,H., Hou,Q., Liu,K., Yao,L. and Wang,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2017) Department of Mcrobiology, Shandong
            Agricultural University, No.61 Daizong Street, Taian, Shandong
            271018, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 2.3
            Expected Final Version            :: yes
            Genome Coverage                   :: 88.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 07:12:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,975
            CDSs (total)                      :: 6,876
            Genes (coding)                    :: 6,711
            CDSs (with protein)               :: 6,711
            Genes (RNA)                       :: 99
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 165
            CDSs (without protein)            :: 165
            Pseudo Genes (ambiguous residues) :: 0 of 165
            Pseudo Genes (frameshifted)       :: 74 of 165
            Pseudo Genes (incomplete)         :: 97 of 165
            Pseudo Genes (internal stop)      :: 5 of 165
            Pseudo Genes (multiple problems)  :: 9 of 165
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:17:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1238953
            Orig. end                         :: 1265608
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP021744.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26655
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="12"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26655
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26655
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16655](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16655)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(247..1113)
                     /locus_tag="SMD11_RS05280"
                     /old_locus_tag="SMD11_1089"
     CDS             complement(247..1113)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981505.1"
                     /locus_tag="SMD11_RS05280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1089"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_087925309.1"
                     /transl_table=11
                     /translation="MADARPTGAPTVLRVVLGKRLQDLRERAGLSFEQAGRALDVTHAT
                     VRRMEKAEVGLKLPYVEKLLRVYGVADPEELDGFLTLAREANRPGWWHRFRDVLPEWFS
                     AFVSLEGEANLIRAYEPHYVPGLLQTEAYARAVLRAGMPHAPDADIDRAVTVRRERQAL
                     LTRDGAPLLWVVMDETVLRRPIGGPGVMREQIAHLAAATAMPNVRLQIMPFAAGPHPAM
                     YGPFHIFRFPLPELPDIAYAENLVGASYFDQRDDVSAFLEALDRMCAQAAPAHTTEAFL
                     GGIRKEI"
     misc_feature    1169..1186
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     misc_feature    1197..1211
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.01"
                     /tool="antismash"
     misc_feature    1203..1215
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.55"
                     /tool="antismash"
     misc_feature    complement(1207..1221)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.79"
                     /tool="antismash"
     misc_feature    complement(1209..1223)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.58"
                     /tool="antismash"
     gene            1260..1718
                     /locus_tag="SMD11_RS05285"
                     /old_locus_tag="SMD11_1090"
     CDS             1260..1718
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004941347.1"
                     /locus_tag="SMD11_RS05285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1090"
                     /product="ATP-binding protein"
                     /protein_id="WP_234365914.1"
                     /transl_table=11
                     /translation="MVPSHDAPSLGRYGSSIAARLQDAFHFPALNTSVAEARRRVLARL
                     REWGIDEVACDDAQLVVSELFTNAVRHTDSDKVSCQLRLSGAHLRIEVADQGHTSTEPR
                     ARCSGADEESGRGLLLVGALSKAWGVRPDDDGRGRVVWADLPHGRLPL"
     gene            complement(1787..2578)
                     /locus_tag="SMD11_RS05290"
                     /old_locus_tag="SMD11_1091"
     CDS             complement(1787..2578)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542873.1"
                     /locus_tag="SMD11_RS05290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1091"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_087925311.1"
                     /transl_table=11
                     /translation="MADDSNSFSKSAIGSYAAVGDSFTEGVGDPGPDDTFIGWADRLAV
                     LLSDQQDEHTFRYANLAVRGRLLDQIVEEQVPRAKELGPDLVTFCAGGNDILRPGSDPD
                     DVAERYEAAVVDLASSVGTVLLCTGFDTRGVPVLRHLRGKIATYTAHVRAIADRHDCPV
                     LDLWSLRSVQDRRAWSDDRLHLSPDGHTRVALRAAQVLGLQVPADPDQAWPDEGLRSPA
                     EVRRDNIHWAREHLVPWIGRRLRGESSGDHVEPKRPDLLPL"
     gene            2791..3594
                     /locus_tag="SMD11_RS05295"
                     /old_locus_tag="SMD11_1092"
     CDS             2791..3594
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049665.1"
                     /locus_tag="SMD11_RS05295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1092"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_087925312.1"
                     /transl_table=11
                     /translation="MTQTPHVPSTEPELAGVRNFRDLGGLPAADGRRVRPGVLFRSGHL
                     AHATESDTRFLDSLGLHTVFDFRNAADIELDGTDVELTGVRNVNIPLNDPADGAEFWRM
                     VRARDLTQLRSVLSGTRGADRMTETYREIVTTRTAEHARVLNALAEDAVPALMHCAAGK
                     DRAGLSIAVTLLALGASRETIEADYLKSNAPHRRYRMHRAEGAGEEELEVAELLSPMFE
                     ARAEYLAEAFATIEEIWGTTERYLTQGLGFGGADRERLRARLLTD"
     gene            complement(3653..5059)
                     /locus_tag="SMD11_RS05300"
                     /old_locus_tag="SMD11_1093"
     CDS             complement(3653..5059)
                     /NRPS_PKS="Domain: Aminotran_3 (48-370). E-value: 8.7e-90.
                     Score: 293.1. Matches aSDomain:
                     nrpspksdomains_SMD11_RS05300_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492039.1"
                     /locus_tag="SMD11_RS05300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1093"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_087925313.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.4e-87, bitscore:
                     292.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPDGTDGAKGFDLARLLAERGGERYDLHTRHLNHQLPRMLRTIG
                     FDKVYERAEGAYFWDAEGRDYLDMLAGFGVMGVGRHHPVVRKALHDVLDASLADLTRFD
                     CQPLPGLLAEKLLSYTPHLDRVFFGNSGTEAVETALKFARYATGRPRVLYCDHAFHGLT
                     TGSLSVNGETGFRDGFAPLLPDTAIPLGDLDALERELRRGDVAAFVVEPIQGKGVHEPP
                     PGFLRAAQDLLRRHKALLIADEVQTGIGRTGDFYAYQHEEGVEPDLVCVAKALSGGYVP
                     VGATLGKDWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMEDEELVAGARHTGE
                     LLRSRLAALVGKYELLHDVRGRGLMIGIEFGRPGSLGLRSRWAMLQAARKGLFAQMVVV
                     PLLQKHRILTQVSGDHLEVIKLIPPLTIGEREVDRFVTAFTAVMDDAHGGGGLMWDFGR
                     TLVKQAVANR"
     aSDomain        complement(3950..4915)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SMD11_RS05300_Aminotran_3.1"
                     /evalue="8.70E-90"
                     /label="SMD11_RS05300_Aminotran_3.1"
                     /locus_tag="SMD11_RS05300"
                     /protein_end="370"
                     /protein_start="48"
                     /score="293.1"
                     /tool="antismash"
                     /translation="VYERAEGAYFWDAEGRDYLDMLAGFGVMGVGRHHPVVRKALHDVL
                     DASLADLTRFDCQPLPGLLAEKLLSYTPHLDRVFFGNSGTEAVETALKFARYATGRPRV
                     LYCDHAFHGLTTGSLSVNGETGFRDGFAPLLPDTAIPLGDLDALERELRRGDVAAFVVE
                     PIQGKGVHEPPPGFLRAAQDLLRRHKALLIADEVQTGIGRTGDFYAYQHEEGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMEDE
                     ELVAGARHTGELLRSRLAALVGKYELLHDVRGRGLMIGIEF"
     gene            complement(5056..7005)
                     /gene="dxs"
                     /locus_tag="SMD11_RS05305"
                     /old_locus_tag="SMD11_1094"
     CDS             complement(5056..7005)
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014175180.1"
                     /locus_tag="SMD11_RS05305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1094"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_087925314.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 1.6e-108,
                     bitscore: 360.7, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.7e-06, bitscore:
                     24.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLLENIRGPRDVKALDTEDLTELAEEIRHFLVHAVARTGGHLGP
                     NLGVVELTIALHRAFDSPADRVLWDTGHQSYVHKLLTGRQDFSKLRGKGGLSGYPSREE
                     SEHDVIENSHASTVLGWADGLAKANQVLGRWNRHVVAVIGDGALTGGMAWEALNNIAAA
                     KDRPLIIVVNDNERSYAPTIGGLADHLATLRTTDGYERFLSWGKDAVQSVPVLGKPLYE
                     SLHGAKKGFKDAFAPQGMFEDLGLKYLGPIDGHDIEAVESALRKAKRFHGPVLVHCRTE
                     KGRGYQPALEDEADRFHTVGVMNPLTCEPLAPAAGRSWTSVFGDEMLRIGSERPDVVAI
                     TAAMLHPVGLTKFAAAYPDRVWDVGIAEQHAATSAAGLATGGLHPVFAVYATFLNRAFD
                     QVLMDVALHKCGVTFVLDRAGVTGTDGASHNGMWDMSILQVVPGLRIAAPRDADQLRAQ
                     LREALDVDDAPTVIRFPKETVGEPLPATAKIGGMDVIGGPGPEEEPAEVLLVAVGTMAP
                     VCLAAAELLTARGTSCTVLDPRWVKPVDEALPAYAARHRVVAVVEDNSRTGGVGSAVAQ
                     ALRDAEVDVPVRTFGIPEQFLPHAKRGEVLADLGLTPAEIAGRISAALARKEVTAAAPA
                     AAGRTSKARKENDA"
     misc_feature    complement(6986..7002)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.77"
                     /tool="antismash"
     gene            complement(7151..8317)
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="SMD11_RS05310"
                     /old_locus_tag="SMD11_1095"
     CDS             complement(7151..8317)
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018534474.1"
                     /locus_tag="SMD11_RS05310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1095"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_087925315.1"
                     /transl_table=11
                     /translation="MGSVEPVSLGLPGLPARPLAKRRPSRRIQVGSVPVGGDAPVSVQS
                     MTTTVTADIGATLQQIAELTASGCQIVRVACPSQDDAEALPVIAKKSQIPVIADIHFQP
                     KYVFAAIDAGCAAVRVNPGNIRQFDDKVREIAKAAADAGTPIRIGVNAGSLDRRLLEKY
                     GKATPEALVESALWEASLFEEHGFRDIKISVKHNDPVVMINAYRQLAAQCDYPLHLGVT
                     EAGPAFQGTIKSAVAFGALLSEGIGDTIRVSLSAPPAEEIKVGMQILESLGLRQRRLEI
                     VSCPSCGRAQVDVYKLADQVTAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGK
                     GQIFVKGEVIKTVPESKIVETLIEEAMKIAETMEAAGAGSGTPDVTVS"
     gene            complement(8323..9345)
                     /gene="hpnH"
                     /locus_tag="SMD11_RS05315"
                     /old_locus_tag="SMD11_1096"
     CDS             complement(8323..9345)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602010.1"
                     /locus_tag="SMD11_RS05315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1096"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_087925316.1"
                     /sec_met_domain="PF04055 (E-value: 3.2e-17, bitscore: 62.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 8.1e-09, bitscore: 33.9,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIRVGTYLFEQKLRRREKFPLIVELEPLFACNLKCEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVAKRKYVF
                     LCTNALLMRKKMEKFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVEAIKEAKRRGF
                     RVTTNSTFFNTDTPQTIIEVLNFLNDDLQVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKAFSGGNRGRWRLNHSPLFLDFLEGKADFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELIEETDWEKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAARETVAGNRG
                     "
     gene            complement(9351..10001)
                     /locus_tag="SMD11_RS05320"
                     /old_locus_tag="SMD11_1097"
     CDS             complement(9351..10001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004951795.1"
                     /locus_tag="SMD11_RS05320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1097"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_087925317.1"
                     /transl_table=11
                     /translation="MPHGTGTPGPAPLLVACALGIERLALRGGGLGGAAGPVTVLRTGM
                     GPAAADQAVTRALADDGMRYASVIATGFCAGLAPGMHPGDLVVADETRDAEGRTECAGA
                     ELLAKELARVAPRRVIHTGPLVGSDHVVRGAERSGLHAAGALAVDMESAATLRSAVRTG
                     PRPVAAVRVVVDAPEHELVRIGTLRGGISAFRVLRTVLPAFIEWHRSLLLPRR"
     misc_feature    complement(9369..9371)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..12004)
                     /gene="shc"
                     /locus_tag="SMD11_RS05325"
                     /old_locus_tag="SMD11_1098"
     CDS             complement(10001..12004)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116600.1"
                     /locus_tag="SMD11_RS05325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1098"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_087925318.1"
                     /sec_met_domain="T2TS (E-value: 6.2e-151, bitscore: 502.3,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGAPPLPAAAAKDSTTVTPPPDGGPAAATTAAERATA
                     RAVDHLLSRQDPEGWWKGDLQTNVTMDAEDLLLRQFLGIQDERTTRAAALFIRSEQRPD
                     GTWATFLGGPPELSATIEAYVALRLAGDAPDAPHMAAASAWIRARGGIAASRVFTRIWL
                     ALFGWWKWDDLPELPPEIMYVPKWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFAL
                     DELHTDPRRPNPPRPLAPATSWDGVFQRLDKALHRYRRFPVKPLRRAALNAAARWIIER
                     QENDGCWGGIQPPAVYSVIALHLLGYDLDHPVLRAGLASLDRFAVWREDGSRMIEACQS
                     PVWDTCLAAIALADAGVAPDHPALVKAADWMLDEQILRPGDWTVRRPELPPGGWAFEFH
                     NDNYPDIDDTAEVVLALKRVAHPDRARLDAAVERAARWNLGMQSKDGAWGAFDADNTSP
                     FPNRLPFCDFGEVIDPPSADVTAHVVEMLAVLGRQHDPRTRRGIEWLLAEQEENGGWFG
                     RWGVNYVYGTGSVVPALVTAGLPASHPAIRRAVRWLESVQNDDGGWGEDLRSYRDPEWI
                     GRGASTPSQTAWALMALLAAGERDGKAVERGVARLVETQAEDGSWDEPHFTGTGFPWDF
                     SINYHLYRQVFPLTALGRYVHGEPFAADRQEA"
     misc_feature    12113..12128
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.37"
                     /tool="antismash"
     gene            complement(12121..13260)
                     /locus_tag="SMD11_RS05330"
                     /old_locus_tag="SMD11_1099"
     CDS             complement(12121..13260)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010266773.1"
                     /locus_tag="SMD11_RS05330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1099"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_087925319.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.5e-62, bitscore:
                     208.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEASHQASRSPDGARTSTTTRGETVTSAIPAVDTAGVNALLERG
                     RTLATPVLRAAVDRLAPPMDTVAAYHFGWIDAQGRPAHGDGGKAVRPALALLSAEAAGA
                     PPETGIPGAVAVELVHNFSLLHDDLMDGDEQRRHRDTVWKVYGPEQAILVGDALFALAN
                     EILLELGTVEAGRATRRLTTATRKLIDGQAQDISYEHRERVTVEECLEMEGNKTGALLA
                     CAVSIGAVLGGADDRTADTLEAYGYHLGLAFQAVDDLLGIWGDPEATGKQTWSDLRQRK
                     KSLPVVAALAAGGPASERLADILAADAKLGESQTADFDEEEFASRAALIEEAGGREWTS
                     QEARRQHATAIEALDGVDMPAQVRAQLTALADFVVVRKR"
     gene            complement(13257..14717)
                     /gene="hpnE"
                     /locus_tag="SMD11_RS05335"
                     /old_locus_tag="SMD11_1100"
     CDS             complement(13257..14717)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018100145.1"
                     /locus_tag="SMD11_RS05335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1100"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_087925320.1"
                     /sec_met_domain="DAO (E-value: 1.3e-09, bitscore: 36.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPRTTTRTGRERAHDATPSTGATAVVVGGGLAGITAALELADA
                     GLRVTLLEGRPRLGGLAFSFRRGDLTIDNGQHVYLRCCTAYRWFLDRVEAAALAPLQPR
                     LDVPVLDVGHPSGKPRLGRLRRTALPVPLHLAASLATYPHLSLAERAKVGRAALALGAL
                     DLDDPALDDEDFASWLHRHGQSPRAVEALWDLVGVATLNATADRSSLGLAAMVFKTGLL
                     SEPGAADIGWARVPLGELHDTRARAALDKAGVRTELRTRATSLTRAEDGRWQVDTEAGA
                     GGTERLDADAVVLAVPQRETHALLPEGALDDPDRLLGIDTAPILNLHVVYDRKVLRQPF
                     FAALGSPVQWVFDRTDSSGLAARGTGGQYLAVSQSAAHDDIDRPVAELRARYLPELERL
                     LPAARGAGVRDFFVTRERTATFAPTPGVGGLRPGAPTATPGLFLAGAWTATGWPATMEG
                     AVRSGVQAAAAALSELGRPHHHPLREPA"
     gene            complement(14809..15759)
                     /gene="hpnD"
                     /locus_tag="SMD11_RS05340"
                     /old_locus_tag="SMD11_1101"
     CDS             complement(14809..15759)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972236.1"
                     /locus_tag="SMD11_RS05340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1101"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_087925321.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.9e-58, bitscore:
                     195.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.4e-67,
                     bitscore: 225.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGTVNGSPDASAPVLAAYSYCEAVTGQQAGNFSYGIRLLPTAKR
                     RAMSALYAFSRRVDDIGDGPLDPAAKQRRLEETRALLARIREGGIEDDDTDPVAVALSH
                     AARRFPIPLGGLDELIDGVQMDVRGESYETWDDLAVYCRCVAGAIGRLSLGVFGTVPGA
                     RDAARAAEYADTLGLALQLTNILRDVREDAANGRTYLPADDLAKFGCAAGFHSAKPPAG
                     ADFTGLVHFEVRRARALFAEGTKLLPMLDRRSGACVAAMSGIYRRLLDRIAEEPEAVLR
                     GRVSLPGREKVYVAVRGLSGLDARGVGRRTAGGRA"
     gene            complement(15756..16655)
                     /gene="hpnC"
                     /locus_tag="SMD11_RS05345"
                     /old_locus_tag="SMD11_1102"
     CDS             complement(15756..16655)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019985319.1"
                     /locus_tag="SMD11_RS05345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1102"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_087925322.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.7e-35, bitscore:
                     120.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.3e-36,
                     bitscore: 124.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAGTAAHERAVLDKAAHENFPVAPFFLPRAWRDDLMAVYGYARL
                     VDDIGDGDLAPGGRDAELLGLDREQADDRPALLDAFEADLLRVFDTTGTGPRHPLLLRL
                     RPTVRRCGLTAEPFLGLIAANRQDQHVTRYATYADLLAYCELSANPVGRLVLGITGTAS
                     PERIRRSDAVCTGLQIVEHLQDVAEDLGRDRVYLPAEDMQRFRVDEADLARPTSGASLR
                     ALVAYEAERAGELLNEGTPLVGSVHGRLKLLLAGFVGGGRAALRAVAAAGHDVLPGPPK
                     PTKLSLLREVGATLRREG"
     misc_feature    16957..16967
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            complement(17086..17898)
                     /locus_tag="SMD11_RS05350"
                     /old_locus_tag="SMD11_1103"
     CDS             complement(17086..17898)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009188923.1"
                     /locus_tag="SMD11_RS05350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1103"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_087925323.1"
                     /transl_table=11
                     /translation="MAEQNPTGAPEVPAAPSGPRIPTVIADDVHIVYRVYGGSTGRGSA
                     TAALNRLVRRTPGAGVREVHAVKGVSFTAYRGEAIGLIGSNGSGKSTLLKAIAGLLPAE
                     RGKVYTDGQPSLLGVNAAMMNDLTGEKNVMLGGLAMGMSREQIRERYQGIVDFSGINEK
                     GDFITLPMRTYSSGMAARLRFSIAAAKDHDVLMIDEALATGDRSFQKRSEARIRELRKE
                     AGTVFLVSHNNRSIRDTCDRVLWLEHGQLLMDGPTEEVVRAYEKETAR"
     gene            complement(17891..18826)
                     /locus_tag="SMD11_RS05355"
                     /old_locus_tag="SMD11_1104"
     CDS             complement(17891..18826)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994380.1"
                     /locus_tag="SMD11_RS05355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1104"
                     /product="ABC transporter permease"
                     /protein_id="WP_087925324.1"
                     /transl_table=11
                     /translation="MSETTHDSAVAMSAPPSPDDGLSAAELAKKYGLAVSGARPPLGEY
                     ARQLWARRHFILAFSRAKLTAQYSKAKLGQVWQVATPLLNATVYFLIFGLLMQQSKGMG
                     IRTYIPFLVTGIFVFTFTQSSAMAGVRAISGNLGLVRALHFPRAALPISFALQQLQQLL
                     YSMVVLFLFLLGFGHMPSLSWLLIVPVLVLQFCFNTGLAMVLARAGSKTPDLAQLLPFV
                     TRTWMYASGVMYSLVDALEKAKAPGWVVDVLSANPAAVYIDLMRWSLIENHSRIHLPPH
                     VWSLALGWALVFGVGGFVYFWKAEEQYGRG"
     misc_feature    complement(18820..18838)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.82"
                     /tool="antismash"
     gene            complement(18905..19795)
                     /locus_tag="SMD11_RS05360"
                     /old_locus_tag="SMD11_1105"
     CDS             complement(18905..19795)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016470903.1"
                     /locus_tag="SMD11_RS05360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1105"
                     /product="glycosyltransferase"
                     /protein_id="WP_087925325.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.8e-11,
                     bitscore: 42.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLGAVVLTMGNRPAELRALLESVAKQDGDPIEVVVVGNGSPLPP
                     LASMAPPGLTVRTVELSENVGIPAGRNVGIEAFGPAGREVDALLFLDDDGLLPGQDTAA
                     LCREAFAADPKLGIVSFRIADPDTGLTQRRHVPRLRASDPMRSSRVTTFLGGANAVRTR
                     VFAEVGGLPDDFFYAHEETDLAWRALDAGWMIDYRSDMVLHHPTTPPSRHAVYHRMVAR
                     NRVWLARRNLPAPLVPVYLGVWLLLTLARRPSMPALRAWLGGFKEGWTTPCGPRRPMKW
                     RTVWRLTRLGRPPVI"
     gene            complement(19825..20610)
                     /locus_tag="SMD11_RS05365"
                     /old_locus_tag="SMD11_1106"
     CDS             complement(19825..20610)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962488.1"
                     /locus_tag="SMD11_RS05365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1106"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_087925326.1"
                     /transl_table=11
                     /translation="MPKPSLAELRPVVHPGGLKDRRSGEHWAGRIYMREISLRCTRVLV
                     DTRLSPNGYTGLMILAGIAAGAALLVPGLTGAILGALLIQLYLLLDCVDGELARWRKVT
                     SITGVYLDRVGHYLSEAALLVGFGIRAADVFHKDGASTQWQWALLGTVAALGAILIKAE
                     TDLVDVARARSGLPAAEDSAATPRSSGMALARKAAAALKFHRLVGGVEASLVILVAGIA
                     DFFHHDLLFTRIAVVLLAAIAVLQTVLHLVSILASSRLK"
     gene            complement(20588..21649)
                     /locus_tag="SMD11_RS05370"
                     /old_locus_tag="SMD11_1107"
     CDS             complement(20588..21649)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413836.1"
                     /locus_tag="SMD11_RS05370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1107"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_087925327.1"
                     /sec_met_domain="Fe-ADH (E-value: 1.1e-20, bitscore: 72.4,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRAGALDDLAKILADQRISSSGKLAIAISG
                     GSGAVLRERLAPALPGASWYEVGGGTLDDAIKLGDAMKKGHYDAVVGLGGGKIIDCAKY
                     AAARVGLPLVAVATNLSHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLDVIREAPVRF
                     VRSGIGDAISNISSVADWELSHRETGEAIDGLAAAMARQAGEAVLRHPGGVGDDGFLQV
                     LAEGLVLTGISMSVAGDSRPASGACHEINHAFDLLYPKRAASHGEQCGLGAAFAMHLRG
                     AREESALMVEVLRRHGLPVLPQEIGFSAEEFVRAVEYAPRTRPGRYTILEHLDLSTDQI
                     RDAYADYAKTVTS"
     gene            complement(21637..22374)
                     /locus_tag="SMD11_RS05375"
                     /old_locus_tag="SMD11_1108"
     CDS             complement(21637..22374)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010640650.1"
                     /locus_tag="SMD11_RS05375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1108"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_087925328.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.5e-12, bitscore:
                     45.6, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVDGDTTILDLTLANFAEI
                     GLTEVAIIVGYRKEAVYARKEALEAKYGLSLTLIDNDKAEEWNNAYSLWCGRDALKDGV
                     ILANGDTVHPVSVERTLLAARGKGQKIILALDTVKQLADEEMKVVVDPEKGVQKITKLM
                     DPAEATGEYIGVTLIEGEAAAELADALKVTFERDPDLYYEDGYQELVNRGFKVDVAPIG
                     DVKWVEIDNHDDLAKGRGIACQY"
     gene            complement(22371..24245)
                     /locus_tag="SMD11_RS05380"
                     /old_locus_tag="SMD11_1109"
     CDS             complement(22371..24245)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="SMD11_RS05380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1109"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_087925329.1"
                     /transl_table=11
                     /translation="MSTAILTGPPPVGSSLEEDLRSLGFDVRVATDVTGALAAVPATER
                     VALVDPGFVGHVHALRLALTDPRFPAAAVEGALTAQPDARASLTRALGTVTTGRPARAT
                     GPDAAPDNDSEEPGHHPSGPHGPAAELPGAVAARLEADGVAVHRPELGVLVAAVPHGDE
                     ARAKTLAEVGAVDDEAVRLRNAVKSRDGFFTTFCISPYSRYLARWCARRGLTPNQVTTA
                     SLLTALIAAGCAATGTRGGFVAAGALLLFSFVLDCTDGQLARYSLQYSTLGAWLDATFD
                     RAKEYAFYAGLALGASRGGGHDDVWALALGAMVLMTCRHVVDFAFNEANHDATANTSPT
                     AALSGRLDSVGWTVWVRRMIVLPIGERWALIAVLTALTTPRVVFVVLLIGCAFAACYTT
                     AGRVLRSLTRKARRTDRAAQALADLADSGPIAEAAGRTLGATVPGRAYGPPFWAVLATA
                     CLLIGPLLTGNGGSWRAVLQAVVYALFAGVAVAQPLKGPLDWLVPPVFRAAEYGLVLTL
                     AAQSDAPGALPAAFGLVAAVAYHHYDTVYRIRGGTGAPPHRLVRAIGGHEGRVLAVSIA
                     AALWHGQGFTIALTVLAAALAITVLIESIRFWVSSGAPAVHDESGEPA"
     gene            24513..25502
                     /gene="galE"
                     /locus_tag="SMD11_RS05385"
                     /old_locus_tag="SMD11_1110"
     CDS             24513..25502
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (65-207). E-value:
                     3.2e-09. Score: 28.2. Matches aSDomain:
                     nrpspksdomains_SMD11_RS05385_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358595.1"
                     /locus_tag="SMD11_RS05385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1110"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_087925330.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.7e-16, bitscore:
                     58.2, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 6.9e-11,
                     bitscore: 40.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMVAAGERVAVLDDLSTGVAGRLPGEC
                     ELVRGSVLDREVLDSAFARLGVTGVVHLAAKKQVGESVEKPLLYYRENMHGLTVLLEAA
                     VAANVGSFVFSSSAAVYGMPDVDLVTEKTPCLPMNPYGETKLAGEWLVRATGSAYGMST
                     ACLRYFNVAGAATPELADTGVYNIIPMMFDRLGRGESPRIFGDDYATPDGTCVRDYIHI
                     EDLATAHLAAARRLAERPGSGDLTLNVGTGHGVSVREMADLIAEVTGHHSPAPVVEPRR
                     PGDPARVVASNELIARELGWSPAHDVRGMVSSAWEGWCHHHPGARVPA"
     CDS_motif       24516..24590
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SMD11_RS05385_0001"
                     /evalue="1.30E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="SMD11_RS05385"
                     /protein_end="26"
                     /protein_start="1"
                     /score="21.1"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMVAAGER"
     aSDomain        24708..25133
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SMD11_RS05385_NAD_binding_4.1"
                     /evalue="3.20E-09"
                     /label="SMD11_RS05385_NAD_binding_4.1"
                     /locus_tag="SMD11_RS05385"
                     /protein_end="207"
                     /protein_start="65"
                     /score="28.2"
                     /tool="antismash"
                     /translation="GVTGVVHLAAKKQVGESVEKPLLYYRENMHGLTVLLEAAVAANVG
                     SFVFSSSAAVYGMPDVDLVTEKTPCLPMNPYGETKLAGEWLVRATGSAYGMSTACLRYF
                     NVAGAATPELADTGVYNIIPMMFDRLGRGESPRIFGDD"
     misc_feature    complement(25546..25560)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            25654..26601
                     /locus_tag="SMD11_RS05390"
                     /old_locus_tag="SMD11_1111"
     CDS             25654..26601
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009339288.1"
                     /locus_tag="SMD11_RS05390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_1111"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_087925331.1"
                     /transl_table=11
                     /translation="MGAGHDHGHSHGGPPPGAGGTAAAAYRGRLRIALGITLTVLAAEI
                     VGSALTGSLALLADAGHMATDAVGVGMALVAIHFANRPAGGRRTYGYARAEILAALLNC
                     LLLLGVGGFILVEAIERLANPTEVPGGMTVVFGLVGVVANLISLGLLMRGQKESLNVRG
                     AFLEVLSDALGSLAVVVSALVIMATGWTQADPVASLLIGLMIVPRTVKLFREALDVLLE
                     AAPRNVDIDEIRSHIMALPGVEDLHDLHVWTITSGMPVLSAHVVVDHAALDSVGHEKML
                     HDLQGCLGEHFDVEHCTFQLEPGGHAEHEARLCH"
ORIGIN
        1 actcgttccc gcgagaagga agtcggcttc gccggccttc gcgcctttga tgaagctttc
       61 gatttcgtgg tgcgtgtaga tcagcgcggg gccgtccgga tcggtggact gacggagcgc
      121 gacccggccg tcccgcagcc gcatggcctc gacgcagctt ccgccgttgc cgccgctcca
      181 cggcttgctc cacccctcgg tgccgaggtc ggtggcgggc atgccgttgt atatgcgatc
      241 catggatcag atctccttac gaatgccacc caggaaggcc tcggtggtgt gtgccggcgc
      301 ggcctgcgcg cacatccggt ccagcgcctc caggaaggcc gagacatcgt cacgctggtc
      361 gaagtacgag gccccgacga ggttttcggc gtacgcgatg tccggcagct ccgggagcgg
      421 gaaccggaag atatggaacg gtccgtacat cgccgggtgc ggcccggcgg cgaacggcat
      481 gatctggagc cgtacgttcg gcatggcggt ggcggccgcg aggtgggcga tctgctcgcg
      541 catgacgccg gggccgccga tgggccggcg cagcacggtc tcgtccatca ccacccacag
      601 cagcggcgcc ccgtcccggg tgagcagcgc ctgccgctcc cggcggacgg tgaccgcgcg
      661 gtcgatgtcg gcgtcggggg cgtgcggcat cccggcgcgg aggacggccc gggcgtaggc
      721 ctccgtctgg agcagtccgg ggacgtagtg cggctcgtac gcgcggatga ggttggcctc
      781 gccctcaagg gagacgaagg cgctgaacca ctcgggcagg acgtcccgga agcggtgcca
      841 ccagcccggg cggttggcct cccgggcgag cgtgaggaag ccgtcgagct cctcggggtc
      901 ggcgacgccg tagacgcgca ggagcttctc cacgtagggg agcttcaggc cgacctcggc
      961 cttctccatc ctgcggaccg tggcgtgggt gacgtcgagg gcacggcccg cctgctcgaa
     1021 ggagaggccg gcccgctccc tgaggtcctg gagccgtttg cccagcacga ccctcaggac
     1081 ggtcggggcg cctgtcggcc gcgcgtccgc cactgttcat cccctccaac ttttgtcata
     1141 tgccccccgt gcagcgcagt ctgccacgca ccccctggag cggacagact gatctgacga
     1201 ttctgcaatt tgcagattga accttgccac acatgactca catcgcacat agttgcggag
     1261 tggtcccctc ccatgacgca ccttcgctcg gacgctacgg cagttccata gccgcgcgtc
     1321 tccaggacgc cttccacttc ccggctctca acacctcggt agcggaggcg cgcagacgag
     1381 ttctcgcgcg gctgcgggag tggggtatcg acgaagtggc gtgcgacgac gctcaattgg
     1441 tggtgtcgga actcttcacc aatgccgtgc ggcacacgga cagcgacaag gtcagctgtc
     1501 aactgcgcct gagcggcgcg catctgcgga tagaggtggc cgatcagggc cacacctcga
     1561 cggagccccg ggcccggtgc agcggggcgg acgaggagag cgggcgcgga ctgctgctgg
     1621 tgggcgcgct gtcgaaggca tggggggtcc ggcccgacga cgacggccgt ggccgtgtcg
     1681 tctgggccga tctgccgcac gggcggctcc ccctctgaca cccgggccgg aacccggtgt
     1741 ccttccccct ctttttctga atttttcggg cgctgcctac agccgcctac agcggcagca
     1801 ggtccggccg cttgggctcc acgtgatcac ccgaggactc gccgcgcagc cggcggccga
     1861 tccacggcac caggtgctcg cgcgcccagt ggatgttgtc ccggcgcacc tcggcgggcg
     1921 accgcagccc ctcgtccggc cacgcctggt ccgggtcggc cggtacctgg agcccgagca
     1981 cctgggcggc gcgcagcgcg acgcgggtgt gcccgtcggg cgagaggtgc agccggtcgt
     2041 cgctccaggc ccgccggtcc tgcaccgagc gcagcgacca caggtcgagg accgggcagt
     2101 cgtgccggtc ggcgatggcg cggacatgcg ccgtgtacgt cgcgatcttg ccgcgcagat
     2161 ggcgcaggac cgggacgccc cgggtgtcga agccggtgca cagcagcacc gtgccgacgg
     2221 aggaggccag gtcgacgacg gccgcctcgt agcgctcggc cacgtcgtcg gggtcgctgc
     2281 cggggcgcag gatgtcgttg ccgccggcgc agaaggtcac gaggtccggg ccgagctcct
     2341 tggcccgggg cacctgctcc tcgacgatct ggtcgaggag ccggccgcgg acggcgaggt
     2401 tggcgtaccg gaaggtgtgc tcgtcctgct ggtcggagag gagtacggcc agtcggtcgg
     2461 cccagccgat gaaggtgtcg tccggccctg ggtcgccgac gccttcggtg aagctgtccc
     2521 cgacggctgc gtacgacccg atcgcgctct tgctgaatga attcgaatcg tctgccacgt
     2581 cagcacatct ttcctcttgg ggagtgactt acgccaccgt aaccaggggt tgacgtgccg
     2641 tgatgtatcc caccccaaca aagtcacccc aagcggaata cgtcaacacc ggtgtcgcgc
     2701 ggcctggatt ccgcgtacaa ccagtggcgt agagtcgttc agccgcctgg tcgacgagca
     2761 acgtcgacag ccgagacctg gggagcgccc gtgacgcaga cgccacatgt cccgtccacc
     2821 gaacccgagc tcgcgggggt acgcaacttc cgtgatctgg gcggcctgcc ggccgccgac
     2881 ggacggcgtg tacggcccgg cgtcctcttc cgcagcggcc acctcgccca cgcgaccgag
     2941 tcggacaccc gcttcctcga ctcgctgggc ctgcacacgg tcttcgactt ccgcaacgcc
     3001 gccgacatcg agctggacgg cacggacgtc gagctcaccg gggtgcgcaa tgtgaacatc
     3061 ccgctcaacg acccggcgga cggcgccgag ttctggcgga tggtccgcgc ccgcgacctc
     3121 acccagctgc ggagcgtgct ctcgggcacc cggggcgcgg accggatgac cgagacgtac
     3181 cgcgagatcg tcaccacccg caccgccgag cacgcccggg tgctgaacgc cctcgccgag
     3241 gacgccgtgc ccgcgctgat gcactgcgcc gccggcaagg accgggcggg cctctcgatc
     3301 gccgtcaccc tgctggcgct cggggcctcg cgggagacca tcgaggccga ctacctgaag
     3361 tccaacgccc cgcaccgccg ctaccggatg caccgcgccg agggcgccgg ggaggaggag
     3421 ctggaggtcg cggagctcct ctcgccgatg ttcgaggccc gcgccgagta cctcgcggag
     3481 gccttcgcca cgatcgagga gatctggggg acgaccgagc ggtacctcac ccaggggctc
     3541 ggcttcggcg gcgcggaccg ggagcggctg cgcgcccggc tgctgacgga ctgagccaca
     3601 gggcttcggt ggccggacgg gcggcggcgc gcccgtccgg ccatccggcc ggtcagcggt
     3661 tggccaccgc ctgcttgacc agcgtccggc cgaagtccca catcagcccg ccgcccccgt
     3721 gcgcgtcgtc catcacggcc gtgaaggcgg tcacgaagcg gtccacctcg cgctcgccga
     3781 tggtcagcgg cgggatcagc ttgatcacct ccagatggtc gccggagacc tgggtgagga
     3841 tccggtgctt ctggagcagc ggcaccacga ccatctgcgc gaagaggccc ttgcgcgcgg
     3901 cctggagcat cgcccagcgg ctgcgcaggc ccagcgagcc gggcctgccg aactcgatgc
     3961 cgatcatcag cccgcggccc cggacgtcgt gcagcagctc gtacttcccg accagcgcgg
     4021 ccagccggct ccgcagcagc tccccggtgt gccgggcacc cgcgacgagc tcctcgtcct
     4081 ccatcaccga gagcacggcg aggccggccg ccatggcctg ggcgttggag ccgaagctcg
     4141 ccgagtggac cagcacccgg tccatggagg agtagacctt cttgaagatc cagtccttgc
     4201 cgagggtcgc gcccaccggt acgtagccgc ccgagagcgc cttggcgacg cacaccaggt
     4261 ccggctcgac gccctcctcg tgctggtagg cgtagaagtc gccggtgcgg ccgatgcccg
     4321 tctgcacctc gtcggcgatc agcagcgcct tgtgccggcg cagcaggtcc tgggccgcgc
     4381 gcaggaagcc cggcggcggc tcgtggacgc ccttgccctg gatgggctcg acgacgaagg
     4441 cggcgacgtc gccccggcgc agctcccgct ccagggcgtc gaggtcaccg agcgggatcg
     4501 cggtgtccgg cagcagcggg gcgaagccgt cgcggaagcc ggtctcgccg ttgacggaca
     4561 gggagccggt ggtcaggccg tggaaggcgt ggtcgcagta gaggaccctg ggccggccgg
     4621 tggcgtagcg ggcgaacttc agggcggtct cgaccgcctc ggtgccgctg ttgccgaaga
     4681 agacccggtc caggtgcggg gtgtacgaca gcagcttctc ggcgaggagg ccgggcagcg
     4741 gctggcagtc gaagcgggtg aggtcggcga gcgaggcgtc caggacgtcg tgcagcgcct
     4801 tgcggacgac ggggtggtgg cggccgacgc ccatcacccc gaagccggcg agcatgtcga
     4861 ggtagtcccg cccctcggcg tcccagaagt acgcgccctc ggcccgctcg tagaccttgt
     4921 cgaagccgat ggtgcgcagc atgcggggca gctggtggtt gaggtgacgg gtgtgcaggt
     4981 cgtaccgctc gccgccgcgc tccgcgagga gccgggcgag gtcgaacccc ttcgcgccgt
     5041 cggtgccgtc gggtgtcatg cgtcgttctc cttacgggcc ttgctggtcc tgccggccgc
     5101 ggccggcgcc gccgccgtca cctccttacg ggccagggcg gcactgatcc ggccggcgat
     5161 ctcggccggg gtgagcccca ggtccgcgag cacctcgccg cgcttggcgt gcgggaggaa
     5221 ctgctcgggg atgccgaagg tgcgcacggg cacgtcgacc tcggcgtcgc gcagggcctg
     5281 cgccacggcc gagccgacgc cgcccgtgcg gctgttgtcc tcgaccacgg cgacgacgcg
     5341 gtgccgcgcg gcgtacgcgg gcagggcctc gtcgacgggc ttgacccagc gggggtcgag
     5401 gacggtgcag gaggtgccgc gggcggtgag cagctcggcg gcggccaggc agacgggggc
     5461 catcgtgccg acggcgacga gcagcacctc ggcgggctcc tcctcggggc cggggccgcc
     5521 gatgacgtcc atgccgccga tcttcgcggt ggccgggagg ggctcgccga cggtctcctt
     5581 ggggaagcgg atgacggtcg gggcgtcgtc gacgtccagg gcctcgcgga gctgggcccg
     5641 tagctggtcg gcgtcgcgcg gggcggcgat ccgcaggccg ggcacgacct ggaggatcga
     5701 catgtcccac atgccgttgt gcgaggcgcc gtcggtgccg gtgacgccgg cccggtccag
     5761 gacgaaggtc acgccgcact tgtgcagggc gacgtccatc aggacctgat cgaaggcgcg
     5821 gttgaggaac gtggcgtaga cggcgaagac cgggtgcagg ccgcccgtcg cgaggccggc
     5881 cgccgaggtg gcggcgtgct gctcggcgat gccgacgtcc cagacccggt cggggtaggc
     5941 ggcggcgaac ttggtgaggc ccacggggtg gagcatcgcc gcggtgatgg ccaccacgtc
     6001 cggccgctcg gagccgatcc gcagcatctc gtcgccgaac accgaggtcc aggaccggcc
     6061 ggcggcgggc gccagcggct cgcaggtgag ggggttcatg acgcccacgg tgtggaagcg
     6121 gtccgcctcg tcctccaggg cgggctggta gccgcggccc ttctcggtgc ggcagtggac
     6181 gaggacgggg ccgtggaagc gcttggcctt gcgcagcgcc gactcgacgg cctcgatgtc
     6241 gtggccgtcg atcgggccga ggtacttgag gccgaggtcc tcgaacatgc cctggggggc
     6301 gaaggcgtcc ttgaagccct tcttcgcgcc gtgcagcgat tcgtagagcg gcttgccgag
     6361 cacggggacg ctctggacgg cgtccttgcc ccaggagagg aagcgttcgt agccgtcggt
     6421 ggtgcgcagg gtggcgaggt ggtcggcgag gccgccgatg gtgggggcgt aggagcgttc
     6481 gttgtcgttg acgacgatga tcaggggccg gtccttggcc gcggctatgt tgttcagggc
     6541 ctcccaggcc attccgccgg tgagggctcc gtcgccgatg acggcgacga cgtggcggtt
     6601 ccagcggccg aggacctggt tggccttggc gaggccgtcc gcccagccca ggaccgtgga
     6661 ggcgtggctg ttctcgatga cgtcgtgctc ggactcctcg cgcgaggggt aaccggacag
     6721 gccgcccttg ccgcggagct tggagaagtc ctggcggccg gtgagcagct tgtgcacgta
     6781 ggactggtgg ccggtgtccc acaggacgcg gtcggcgggc gagtcgaagg cgcggtgcag
     6841 cgcgatggtc agctccacca cgccgaggtt gggtccgagg tggccgccgg tcctggccac
     6901 ggcgtgcacc aggaagtggc ggatctcctc tgccagttcg gtcaggtcct cggtgtccag
     6961 tgccttcacg tcgcgcggac cgcggatgtt ctccaacaac gacacgtcgg ggccccctcc
     7021 tcgtctctcg gccccggccg ggcagccctg acggccgctc cttccgggga ctgtctgatc
     7081 tgactgggtg tgcctgcgtc cgaccggtcg gtccggtcgg cctggtctcc ggcgggcgtg
     7141 gccccgtcgg tcagctcacg gtgacatcgg gcgtgcccga gccggcgccc gcggcctcca
     7201 tggtctcggc gatcttcatc gcctcctcga tgagggtctc cacgatcttg gactcgggga
     7261 cggtcttgat gacctcgccc ttgacgaaga tctggccctt gccgttgccc gaggcgacac
     7321 cgagatccgc ctcgcgggcc tcgcccggcc cgttcacgac gcagcccatc acggcgacgc
     7381 gcagcggcac ctccatgccc tccagacctg ccgtaacctg gtcggcgagc ttgtagacgt
     7441 cgacctgggc gcggccgcag gacgggcagg agacgatctc cagacggcgc tgacgcaggc
     7501 ccagggactc caggatctgc atgccgacct tgatctcctc ggccggtggc gccgacaggg
     7561 agacccggat ggtgtcgccg atgccctcgg agagcagcgc gccgaacgcc acggccgact
     7621 tgatcgtgcc ctggaatgcc gggcccgcct cggtgacgcc gaggtgcagc ggatagtcgc
     7681 actgggcggc cagctggcgg taggcattga tcatcacgac cgggtcgttg tgcttgaccg
     7741 agatcttgat gtcacggaag ccgtgctcct cgaagagcga cgcctcccac agcgccgact
     7801 cgacgagcgc ctccggggtg gccttgccgt acttctccag caggcgccgg tccagcgagc
     7861 ccgcgttgac gccgatccgg atgggggttc ccgcgtccgc ggccgccttg gcgatctcgc
     7921 ggaccttgtc gtcgaactgc cggatgttgc ccgggttgac ccggaccgcg gcgcagccgg
     7981 cgtcgatggc cgcgaagacg tacttcggct ggaagtggat gtcggcgatc accgggatct
     8041 gcgacttctt cgcgatgacc ggcagtgcct ccgcgtcgtc ctgcgagggg caggcgaccc
     8101 ggacgatctg gcagccggag gcggtgagct cggcgatctg ctggagcgtc gcgccgatgt
     8161 ccgccgtcac cgtcgtggtc atggactgca ccgacaccgg cgcgtccccg ccgaccggga
     8221 ccgacccgac ctggatgcgc cgcgaggggc ggcgcttcgc cagcggccgg gccggcaggc
     8281 cggggagtcc gagtgagaca ggctccacgg atcccatgcc cgtcagcccc ggtttcccgc
     8341 gacggtctcg cgcgcggcgc gcagcgattc cttcagcgac cccatggtgg cgaggacggc
     8401 tgtgggttcg tagccgcagt gcgccatgca gttggcgcag cgcgggtcct tgccccgccc
     8461 gtacttctcc cagtcggtct cctcgatcag ctcccggtac gtcgggacgt agccgtcgct
     8521 catcaggtag caggggcgct gccagccgaa gagggagtag ttcgggatgg cccacgcggt
     8581 gcaggggaag tcggccttgc cctccaggaa gtcgaggaag agcgggctgt ggttgagccg
     8641 ccagcggccg cggttgccgc ccgagaaggc cttcttgaag agctcccggg tctgctcgac
     8701 gcccaggaag tgctcctggt cgggggcctt ctcgtaggcg taggcgggag agatcatcat
     8761 ctcgtcgacc tggaggtcgt cattgaggaa gttgagcacc tcgatgatgg tctgcggggt
     8821 gtcggtgttg aagaaggtgg aattggtggt gacccggaag ccacgccgct tggcctcctt
     8881 gatcgcctcc accgcctcgt cgaagacgcc ctccttcgca acggattcgt cgtgccgctc
     8941 gcgcagcccg tcgatgtgca ccgcgaaagc gaaatacggt gagggggtga atttctccat
     9001 cttcttacgc atcaacaggg cgttggtgca caggaagaca tactttcgct tcgccaccag
     9061 ctgccgcacg atctcatcga tctgcgggtg catcaggggc tcgccgccgg cgatggagac
     9121 catcggcgca ccggattcca gaaccgcgcc gacggcctgc gcgacgggca tgcgctgctt
     9181 gagcacgccc gccgggtgct ggatcttccc gcagccctcg cacttgaggt tgcaggcgaa
     9241 gagcggctcc agttcgacga tcagcgggaa cttctcccgc ctccgcagct tctgttcaaa
     9301 aaggtaggtt cccacccgga tggactggcg gagcggcatg gccatctggc tcacctcctg
     9361 gggagcagta aagatcggtg ccattcgata aatgccggaa ggacggtgcg gagcacccgg
     9421 aaggctgata ttccaccccg caacgtcccg attcgtacga gttcatgttc tggagcgtcc
     9481 acgaccaccc ggacggccgc aaccgggcgc ggtcccgtgc ggacggcgct tcggagcgtg
     9541 gcggcggatt ccatgtcgac ggcgagcgcc cccgcggcgt gcaggccgga gcgctccgcg
     9601 ccacgcacga cgtggtcgga gccgacgagc gggccggtgt ggatgacgcg ccggggtgcc
     9661 acccgcgcga gctccttggc gaggagctcg gcgccggcgc actccgtgcg gccctcggcg
     9721 tcgcgggtct cgtcggcgac gaccaggtcg ccggggtgca tccccggtgc cagcccggcg
     9781 cagaagccgg tggcgatcac cgaggcgtac cgcatgccgt cgtccgcgag ggcgcgggtg
     9841 acggcctggt ccgcggcggc cgggcccatg cccgtgcgca gtacggtcac gggcccggcc
     9901 gcaccgccga ggccgccccc gcgcagggcg aggcgctcga tgccgagcgc gcaggcgacc
     9961 agcagcggtg cggggccggg ggttcccgtg ccgtggggca tcacgcctcc tggcggtcgg
    10021 cggcgaaggg ctccccgtgg acgtagcggc cgagggccgt gagggggaag acctggcggt
    10081 acaggtggta gttgatggag aagtcccagg ggaatccggt gccggtgaag tgcggctcgt
    10141 cccaggagcc gtcctcggcc tgggtctcca ccagccgggc caccccgcgc tcgaccgcct
    10201 tgccgtcccg ctcccccgcg gcgagcaggg ccatcagggc ccaggccgtc tgggaggggg
    10261 tggaggcgcc gcggccgatc cactccgggt cgcggtacga gcgcaggtcc tcgccccagc
    10321 cgccgtcgtc gttctgcacg ctctccagcc agcgcacggc ccggcggatc gccgggtgcg
    10381 aggcggggag cccggcggtg acgagggcgg ggacgaccga cccggtgccg tagacgtagt
    10441 tgacgcccca gcggccgaac cagccgccgt tctcctcctg ctcggcgagc agccactcga
    10501 tgccgcgccg ggtgcgcggg tcgtgctgcc tgccgaggac ggccagcatc tccaccacgt
    10561 gcgcggtgac gtcggcggac ggcgggtcga tgacctcgcc gaagtcgcag aacggcagcc
    10621 ggttggggaa ggggctggtg ttgtcggcgt cgaaggcgcc ccaggcgccg tccttcgact
    10681 gcatgcccag gttccagcgg gcggcgcgct ccacggccgc gtccagccgg gcgcggtcgg
    10741 gatgggcgac gcgcttgagc gcgaggacga cctcggcggt gtcgtcgatg tcggggtagt
    10801 tgtcgttgtg gaactcgaag gcccagccgc ccgggggcag ttccggcctg cgcaccgtcc
    10861 agtcgccggg ccggaggatc tgctcgtcga gcatccagtc ggcggccttg acgagcgccg
    10921 ggtggtccgg ggccacgccc gcgtcggcga gcgcgatcgc ggcgagacag gtgtcccaca
    10981 ccggggactg acacgcctcg atcatccgcg agccgtcctc gcgccagacg gcgaaacggt
    11041 ccagcgacgc gaggcccgcg cgcagcacgg ggtggtcgag gtcgtagccg aggaggtgca
    11101 gggcgatgac ggagtagacg gcgggtggct ggatgccgcc ccagcagccg tcgttctcct
    11161 ggcgctcgat gatccagcgg gctgcggcgt tgagcgcggc gcggcgcagg ggcttgacgg
    11221 ggaacctgcg gtaccggtgc agcgccttgt ccaggcgctg gaagacgccg tcccagctgg
    11281 tggccggggc gagcgggcgg ggcgggttcg gccggcgcgg gtcggtgtgc agctcgtcca
    11341 gcgcgaaggg cgcggggcgc acgggccgct tcgccgagac gacggtgagc ggcacgatgg
    11401 tctgccgggc ccagcagccg aagtcgtaga tgttgagcgg gacccacttc ggcacgtaca
    11461 tgatctcggg cggcagctcc ggcaggtcgt cccacttcca ccagccgaag agggccagcc
    11521 agatgcgggt gaagacccgg gaggcggcga tgccgccccg cgcgcggatc caggcggagg
    11581 cggcggccat gtgcggggcg tcgggggcgt ccccggcgag cctcagcgcg acataggcct
    11641 cgatggtggc cgagagttcg ggcggtccgc cgaggaaggt ggcccaggtg ccgtcgggcc
    11701 gctgctcgga gcggatgaag agggcggcgg cgcgggtggt ccgctcgtcc tggatcccga
    11761 ggaactggcg gaggagcagg tcctcggcgt ccatggtgac gttggtctgg aggtcgccct
    11821 tccaccaccc ctcggggtcc tgccgggaca ggaggtggtc gaccgccctg gcggtggccc
    11881 gctcggcggc cgtcgtggcc gccgccggcc cgccgtcggg cgggggcgta acggtggtgc
    11941 tgtccttggc cgcggctgcg gggagcggag gggctccggt gcttccgtcg gtcgtcgctg
    12001 tcatggtttc ccctttttgc agtgatcttt cttctctgcc gtgctggggg ctccgtcggc
    12061 cgacgcaccg tcagggcgtc ggccggcgac tgcgatctgc tcagatcggg tgaatgggaa
    12121 tcatctcttt cgtacgacga cgaagtcggc gagcgccgtg agctgggccc gtacctgggc
    12181 cggcatgtcg actccgtcga gggcctcgat cgcggtggcg tgctggcggc gggcctcctg
    12241 ggaggtccac tcccggccgc ccgcctcttc gatcaacgcc gcgcggctgg cgaattcttc
    12301 ctcgtcgaag tcggcggtct gggattcgcc gagcttggcg tcggcggcga ggatgtcggc
    12361 gagccgctcg gaggcggggc cgcccgccgc gagggcggcg acgaccggca gcgacttctt
    12421 gcgctggcgc aggtcgctcc aggtctgctt gcccgtggcc tccgggtctc cccagatgcc
    12481 cagcaggtcg tcgacggcct ggaaggcgag gcccaggtgg tagccgtagg cctccagggt
    12541 gtcggccgtg cggtcgtcgg cgccgccgag gacggcgccg atggagacgg cgcaggcgag
    12601 cagggcgccc gtcttgttgc cctccatctc caggcactcc tcgacggtga cccgctcgcg
    12661 gtgctcgtag gagatgtcct gggcctgacc gtcgatcagc ttccgggtgg cggtggtcag
    12721 ccgccgggtg gcgcggccgg cctcgaccgt gccgagctcc agcaggatct cgttcgcgag
    12781 cgcgaacagc gcgtcgccga ccaggatggc ctgctcgggg ccgtacacct tccacaccgt
    12841 gtcgcggtgc cggcgctgct cgtcgccgtc catcaggtcg tcgtggagca gcgagaagtt
    12901 gtgcacgagc tcgacggcga cggcgccggg gatgccggtc tccggcggtg ctccggcggc
    12961 ctcggccgag agcagggcga gggcgggccg gacggccttg ccgccgtcgc cgtgcgcggg
    13021 cctgccctgg gcgtcgatcc agccgaagtg gtaggcggcg acggtgtcca tgggcggcgc
    13081 gagccggtcc acggcggcac gcagcaccgg cgtggcaagc gtccgtccgc gctccagcag
    13141 ggcgttgacg cctgcggtgt cgacagctgg gatcgccgat gtcacggtct ctcctctggt
    13201 ggtcgtgctc gtacgcgccc cgtcggggga acgcgacgct tgatggctcg cctcggtcat
    13261 gccggctccc gcaaggggtg gtgatgcggt cggcccagct cggagagtgc cgcggcggcg
    13321 gcctggacac cgctgcgcac cgcgccctcc atcgtcgcgg gccagccggt ggcggtccac
    13381 gcgccggcca ggaagaggcc gggcgtggcg gtgggggcgc cgggccgcag cccgccgacc
    13441 cccggggtgg gggcgaacgt cgctgtacgc tcccgggtca cgaagaagtc ccttacgccg
    13501 gcgccgcggg ccgcgggcag cagccgctcc agctccggga ggtagcgcgc gcggagctcg
    13561 gcgacgggcc ggtcgatgtc gtcgtgcgcg gcggactggg agacggccag gtactggccg
    13621 ccggtgcccc gcgcggcgag cccggaggag tcggtgcggt cgaagaccca ctgcaccggg
    13681 gagccgagcg ccgcgaagaa gggctgccgc aggactttgc ggtcgtatac gacgtggagg
    13741 ttgaggatcg gcgcggtgtc gatgccgagc agccggtccg ggtcgtcgag cgcgccctcg
    13801 gggagcaggg cgtgggtctc gcgctggggc acggcgagga ccaccgcgtc ggcgtcgagc
    13861 cgctcggtgc cgccggcccc ggcctcggtg tcgacctgcc agcggccgtc ctcggcccgg
    13921 gtgagcgagg tcgcgcgggt gcgcagctcg gtgcggacgc cggccttgtc gagggcggcg
    13981 cgggcccggg tgtcgtgcag ctcgccgagg ggcacgcgcg cccagccgat gtcggcggcg
    14041 ccgggctcgg agagcaggcc ggtcttgaag accatggcgg ccaggcccag cgaggagcgg
    14101 tcggcggtgg cgttgagggt ggcgacgccg acgaggtccc acagggcctc gacggcgcgc
    14161 ggggactggc cgtggcggtg cagccagctc gcgaagtcct cgtcgtccag cgcggggtcg
    14221 tcgaggtcga gggcgccgag ggcgagcgcg gcacgtccca ccttggcgcg ctcggcgagc
    14281 gagaggtgcg ggtaggtggc caggctcgcg gcgaggtgca gcgggacggg cagggcggtg
    14341 cgccgcagcc ggcccaggcg cggcttgccc gaggggtggc cgacgtcgag cacgggcacg
    14401 tcgagccggg gttgcagcgg cgcgagcgcg gcggcctcga cgcggtcgag gaaccagcgg
    14461 taggcggtgc agcagcgcag gtagacgtgc tggccgttgt cgatggtgag gtcgccgcgg
    14521 cggaaggaga aggcgagccc gccgaggcgg gggcggccct ccagcagggt gacgcggagt
    14581 ccggcgtcgg cgagttcgag cgcggccgtg atgccggcca gcccgccgcc gacgaccacc
    14641 gcggtggctc cggtggaggg ggtcgcgtcg tgcgcgcgct cccgtccggt acgggtcgtc
    14701 gtgcgtggtg tggtcatgcg cccaccccct cggctgctgt cagtgacgta tgccatcggc
    14761 ggagggttgc acaccgcttg ccggtccggg aacggggcgt ccggggcatc aagcgcgccc
    14821 cccggcggtc cgccggccga cgccgcgggc gtcgagaccg gacaggccgc gcacggcgac
    14881 gtacaccttc tcgcggccgg ggagcgagac gcggccgcgc agcacggcct cgggctcctc
    14941 ggcgatgcgg tccagcagcc tgcggtagat gccggacatg gcggcgacgc aggcaccgct
    15001 gcgccggtcg agcatgggga ggagcttggt gccctcggcg aacagcgcgc gggcgcgccg
    15061 gacttcgaag tggaccaggc ccgtgaagtc ggccccggcc ggcggcttcg cggaatggaa
    15121 gcccgcggcg cagccgaact tggcgagatc gtccgccggg aggtaggtgc ggccgttggc
    15181 cgcgtcctcg cggacgtcgc gcaggatgtt ggtgagctgg agcgcgagac ccagagtatc
    15241 ggcgtactca gcggcgcgcg cggcgtcgcg cgcgccgggc acggtgccga acaccccgag
    15301 cgagagccgg ccgatggcac ccgcgacaca gcggcagtag acggcgaggt cgtcccacgt
    15361 ctcgtaggac tcgccacgca catccatctg aacgccgtcg atcagttcgt cgagcccgcc
    15421 gagcggaatc gggaagcggc gcgcggcatg gctgagcgcg acggccaccg ggtcggtgtc
    15481 gtcgtcctcg atgccgccct cgcggatccg ggcgagcagg gcccgggtct cctcgagccg
    15541 ccgctgcttg gccgccgggt ccagcgggcc gtcaccgatg tcgtcgacgc gccgggagaa
    15601 ggcgtagagc gccgacatgg cgcgccgctt ggcggtcggc agcagtctga tgccgtagct
    15661 gaagttgccg gcctgctggc cggtgaccgc ctcgcagtag ctgtacgcgg cgagtaccgg
    15721 cgcggacgcg tctggcgatc cgttcacggt cccgctcacc cctctcttcg cagtgtcgct
    15781 cccacctcgc gcagcaggct gagcttggtg ggcttgggcg gtccgggcag tacgtcgtgt
    15841 cccgcggcgg cgaccgcgcg gagcgcggcc ctccccccgc ccacgaaccc cgcgagcaac
    15901 agcttcaacc tgccgtggac gctacccacc aggggggtgc cttcattcag cagttccccg
    15961 gcgcgttccg cctcgtacgc gaccagggca cgcaacgacg cgccactggt gggacgggcc
    16021 agatcggcct cgtcgacgcg gaagcgctgc atgtcctcgg ccgggagata gacgcggtcg
    16081 cgtccgaggt cctcggcgac gtcctgtagg tgttcgacga tctggagacc cgtgcagacc
    16141 gcgtccgagc ggcggatccg ctcggggctg gcggtgccgg tgatgcccag gaccagacgg
    16201 ccgacggggt tggcggacag ctcgcagtag gcgagcaggt ccgcgtaggt ggcgtagcgg
    16261 gtgacgtgct ggtcctggcg gttggccgcg atcaggccga gaaacggttc agcggtcagg
    16321 ccgcaccggc ggacggtcgg gcgcagccgg agcagcaggg ggtggcgcgg gccggtgccg
    16381 gtggtgtcga agacgcgcag gaggtcggcc tcgaaggcgt cgagcagggc cgggcggtcg
    16441 tccgcctgtt cccggtcgag gcccagcagc tcggcgtcgc ggccgcccgg ggccaggtcg
    16501 ccgtcgccga tgtcgtcgac gaggcgggcg tagccgtaga cggccatgag gtcgtcccgc
    16561 caggctcgcg gcaggaagaa gggtgccacc gggaagttct cgtgcgcggc cttgtcgagc
    16621 acggcgcgct cgtgcgcggc cgtccccgcc gtcaccgggt gctgcccggg cgcgtcgtcg
    16681 ggccgaggac ggcgggagcg ccgcggagct ggagagttcc cgtagccatt gccgtcacat
    16741 ctcccgttct acactgccga cccagaacat cctatttcgg acacgccgca gggcaggcgt
    16801 cccccggtgc cccttgggca cctcccggat ctccctccgg atcacccttc cgaccggggg
    16861 agatacaccg gtatcgcccc gcttctccat aaatcagcac tgtacagcgt acgccgtaca
    16921 gatgtgcggt gcgcgcccgg gtaggtgctt gatccataca atgccacgcg aggggcgaat
    16981 caaccctgac aataagcgag ttgatcgtta cggataggtc aagcccccgc ccgtcggaga
    17041 cggcgggggc cggtgcgcct ggccggaaaa cgcgggctcg cgggactagc gggccgtctc
    17101 cttctcatag gcccggacca cttcctcggt cggtccgtcc atgagcagct gcccgtgttc
    17161 gagccagagc acccggtcgc aggtgtcccg gatcgaccgg ttgttgtggc tgacgaggaa
    17221 gaccgtgccg gcctccttgc ggagctcgcg gatccgggcc tcggagcgct tctggaagga
    17281 ccggtcaccg gtcgccagcg cctcgtcgat catcaagacg tcgtggtcct tggccgcggc
    17341 gatggagaac cgcagccggg ccgccatgcc ggaggagtac gtccgcatcg gcagcgtgat
    17401 gaagtcgccc ttctcgttga tgccggagaa gtcgacgatc ccctggtagc gctcgcggat
    17461 ctgctcccgg gacatgccca tcgccagccc gccgagcatc acgttcttct cgcccgtgag
    17521 gtcgttcatc atggccgcgt tgacgcccag cagcgagggc tggccgtcgg tgtagacctt
    17581 gccgcgctcg gcgggcagca gcccggcgat ggccttgagc agggtcgact tgccggagcc
    17641 gttggagccg atcaggccga tcgcctcacc gcggtaggcg gtgaagctga cgcccttgac
    17701 ggcgtgcacc tcccggacgc cggcccccgg cgtccggcgc accagccggt tgagcgcggc
    17761 ggtcgcgctg ccgcggccgg tgctgccgcc gtagacgcgg tagacgatgt gcacgtcgtc
    17821 cgcgatcacg gtggggatac gggggcccga aggcgcagcg gggacctcgg gggccccggt
    17881 ggggttctgt tcagccacgg ccgtactgct cctcagcctt ccagaagtac acgaagcctc
    17941 cgacgccgaa gaccagcgcc cagccgaggg ccagggacca gacgtgcggc ggcaggtgga
    18001 tcctgctgtg gttctcgatc agcgaccagc gcatcaggtc gatgtagacg gcggccgggt
    18061 tggcgctcag cacgtccacg acccaccccg gcgccttcgc cttctccagc gcgtccacca
    18121 ggctgtacat cacgccggac gcgtacatcc aggtacgcgt gacgaacggc agcagctggg
    18181 cgaggtccgg ggtcttgctg cccgcgcggg ccagcaccat cgcgaggccg gtgttgaagc
    18241 agaactggag caccagcacc gggacgatca gcagccacga gagcgacggc atgtggccga
    18301 agcccagcag gaagaggaag agcaccacca tcgagtacag cagctgctgg agctgctgga
    18361 gcgcgaagga gatcggcagc gccgcccggg ggaagtgcag ggcccgcacc agccccaggt
    18421 tgcccgagat ggcgcggacg cccgccatcg ccgagctctg ggtgaaggtg aagacgaaga
    18481 tgcccgtcac caggaagggg atgtacgtcc tgatccccat ccccttgctc tgctgcatca
    18541 gcaggccgaa gatgaggaag tacaccgtcg cgttcagcag cggcgtggcc acctgccaga
    18601 cctggcccag cttcgccttg ctgtactgcg cggtcagctt cgcccgggag aacgcgagga
    18661 tgaagtggcg ccgcgcccac agctgccggg cgtactcccc cagcgggggc cgggcgccgc
    18721 tcaccgcgag gccgtacttc ttggccagct cggcggcgga gagtccgtcg tcgggggatg
    18781 gcggggcact catggcgacc gcactgtcgt gcgttgtctc gctcacagtt gacactttcg
    18841 tcctcaaggt gcgctcccgg ggtcctgccc cgggacgcgc ccgatgctct cagacaagag
    18901 cttgtcagat cacgggaggg cgacccagtc gggtcaggcg ccacacggta cgccacttca
    18961 tggggcgccg tgggccacag ggggtcgtcc agccctcctt gaagccgcca agccaggcgc
    19021 gcagcgccgg catcgagggc cgcctggcca gggtcagcag cagccacacc ccgaggtaga
    19081 cggggacgag gggcgccggg aggttgcgcc gggccagcca gacgcggttg cgggcgacca
    19141 tgcggtggta gaccgcgtgg cggctcggcg gcgtcgtcgg gtggtgcagg accatgtccg
    19201 agcggtagtc gatcatccag cccgcgtcga gggcccgcca cgcgaggtcg gtctcctcat
    19261 gggcgtagaa gaagtcgtcg ggcaggccgc cgacctccgc gaagacccgg gtgcggaccg
    19321 cgttggcgcc gccgaggaag gtggtcacgc gcgaggaccg catcgggtcc gaggcgcgca
    19381 gccgcggcac gtggcggcgc tgggtgagcc cggtgtcggg gtcggcgatg cggaagctga
    19441 cgatgccgag cttcgggtcg gcggcgaagg cctcgcggca cagcgcggcc gtgtcctggc
    19501 cgggcagcag cccgtcgtcg tccaggaaga gcagcgcgtc gacctcgcgg ccggcggggc
    19561 cgaaggcctc gatgccgacg ttgcggccgg ccgggatgcc gacgttctcg gagagctcga
    19621 cggtccgcac ggtcagcccg ggcggggcca tggaggcgag cgggggcagc ggcgagccgt
    19681 tgccgacgac gacgacctcg atggggtcgc cgtcctgctt ggccaccgac tccagcagcg
    19741 cgcgcagctc ggcggggcgg ttgcccatgg tcaggacgac cgcgccgagc ttcatgctcg
    19801 acgcggcggg agcggaggag gcactcattt cagcctgctg gaagcgagga tggacacgag
    19861 gtggagcact gtctgcaata ccgcgatggc ggcgagcagc acaaccgcga tccgggtgaa
    19921 cagcaggtcg tggtggaaga agtccgcgat gcccgcgacc aggatcacca gggacgcctc
    19981 gacgccgccg accaggcggt ggaacttcag cgccgccgcg gccttgcggg ccagggccat
    20041 gcccgaggag cggggggtgg ccgcggagtc ctccgccgcc ggcagcccgc tgcgggcccg
    20101 ggccacgtcc accaggtccg tctcggcctt gatcaggatc gcgccgagcg cggccacggt
    20161 gcccaggagc gcccactgcc actgcgtgct cgcgccgtcc ttgtggaaga cgtccgcggc
    20221 gcggatgccg aagcccacca gaagggcggc ctcggagagg tagtggccca cccggtcgag
    20281 gtagacgccg gtgatcgagg tgaccttgcg ccagcgcgcg agctcgccgt cgacacagtc
    20341 caggagcagg tacagctgga tgagcagcgc gcccaggatc gccccggtca ggccgggcac
    20401 caggagtgcc gcgccggccg cgatcccggc gaggatcatc agcccggtgt acccgttggg
    20461 cgagagcctg gtgtccacca ggacccgggt gcagcgcagc gagatctccc gcatgtagat
    20521 gcgcccggcc cagtgctcac cgctgcgccg gtccttgagg ccgccggggt ggacgaccgg
    20581 acggagttca gctagtgacg gttttggcat agtcggcgta agcgtccctg atctggtcgg
    20641 tggagaggtc gaggtgctcc aggatcgtgt agcgcccggg gcgggtccgc ggggcgtact
    20701 cgacggccct gacgaactcc tcggcactga agccgatctc ctgcggcagc accggcaggc
    20761 cgtggcgccg cagcacctcg accatcagcg cggactcctc gcgggccccg cggaggtgca
    20821 tggcgaaggc ggcgccgagg ccacactgct cgccgtggct ggcggcccgc ttggggtaga
    20881 gcaggtcgaa ggcgtggttg atctcgtggc acgcgccgga ggcggggcgg ctgtcgccgg
    20941 ccaccgacat ggagatgccg gtgagcacga ggccctcggc gagcacctgg aggaagccgt
    21001 cgtcgccgac gccgccgggg tggcggagca cggcctcgcc ggcctggcgg gccatcgcgg
    21061 cggccaggcc gtcgatcgcc tcgcccgtct cgcggtggga gagctcccag tcggcgacgg
    21121 aggagatgtt ggagatcgcg tcaccgatgc cggagcgcac gaagcggacc ggtgcctcac
    21181 ggatgacgtc gaggtcgatg acgacggcga tggggttggg caccccgtac gagccgcggc
    21241 ccgcgtcgtt gtcgagcgtg gcgacgggcg agcagaggcc gtcgtgcgac aggttcgtcg
    21301 cgacggccac cagcggcagc ccgacccgtg cggcggcgta cttcgcacag tcgatgatct
    21361 tgccgccgcc gaggcccacg accgcgtcgt agtgcccctt cttcatggcg tcgccgagct
    21421 tgatggcgtc gtcgagggtg ccgccgccga cctcgtacca ggaggcgccg ggcagcgccg
    21481 gggcgagccg ctcgcgcagc accgccccgg agccgccgct gatggcgatg gccagcttgc
    21541 cggagctgga gatccgctga tcggcgagga tcttcgccag atcgtccagc gctccggccc
    21601 ggatgtcgac gacgaccggc gaggggatga gcctcgtcag tactggcacg cgatcccccg
    21661 gcccttggcg aggtcgtcgt ggttgtcgat ctcgacccac ttgacgtcgc cgatgggcgc
    21721 cacgtcgacc ttgaagccgc ggttgacgag ctcctggtag ccgtcctcgt agtagaggtc
    21781 ggggtcgcgc tcgaaggtga ccttgagggc gtccgccagc tcggcggcgg cctcgccctc
    21841 gatcagggtg acaccgatgt actcaccggt ggcctcggcc gggtccatca gcttggtgat
    21901 cttctggacg cccttctcgg ggtcgacgac gaccttcatc tcctcgtcgg cgagctgctt
    21961 caccgtgtcg agggcgagga tgatcttctg acccttgccg cgggcggcga ggagggtgcg
    22021 ctcgacggag accgggtgca cggtgtcacc gttggcgagg atcacgccgt ccttgagggc
    22081 gtcgcggccg caccacaggg agtaggcgtt gttccactcc tcggccttgt cgttgtcgat
    22141 cagggtgagg ctcaggccgt acttggcctc cagggcctcc ttgcgggcgt acacggcctc
    22201 cttgcggtag cccacgatga tcgcgacctc ggtcagaccg atctcggcga agttggccag
    22261 ggtgaggtcg aggatggtgg tgtcaccgtc caccggcacc agggccttgg gcagagtgtc
    22321 ggtgtaggga cgcagacgcc gtccggcgcc ggcagccagc acgaggccga tcatgcgggt
    22381 tctcctgatt cgtcgtgtac agcgggcgcc ccggaggaca cccagaaacg gatgctctcg
    22441 atgagcaccg tgatcgcgag ggcggccgcg aggaccgtca gcgcgatggt gaaaccttgg
    22501 ccgtgccaca gggcggcggc gatcgagacc gccaggacgc gtccctcgtg cccgccgatc
    22561 gcccgcacca gccggtgcgg gggcgcgccg gtgccaccgc ggatgcggta caccgtgtcg
    22621 tagtgatggt aggcgaccgc ggccaccagg ccgaaagcag cgggcagggc gccgggggcg
    22681 tccgactgcg cggcgagggt gaggacgagc ccgtactcgg cggcccggaa gaccgggggg
    22741 accagccagt ccagcggtcc cttgaggggc tgggcgacgg cgacgcccgc gaagagcgcg
    22801 tacaccacgg cctggagcac ggcccgccag ctgccgccgt tgccggtgag aagcggtccg
    22861 atcagcaggc aggccgtcgc cagcacggcc cagaaggggg ggccgtaggc gcggccgggc
    22921 acggtggcgc cgagcgtccg gcccgcggcc tcggcgatcg ggccggagtc ggcgaggtcg
    22981 gccagggcct gggcggcccg gtcggtgcgc cgggccttgc gggtcagcga gcgcaggacg
    23041 cggccggcgg tggtgtagca ggcggcgaag gcgcagccga tcagcaggac gacgaagacc
    23101 acgcggggtg tggtgagcgc cgtgaggacc gcgatcagcg cccagcgctc gccgatgggc
    23161 agcacgatca tgcggcggac ccatacggtc cagccgacgc tgtcgagccg gccggagagc
    23221 gcggccgtcg ggctggtgtt ggccgtggcg tcgtggttcg cctcgttgaa agcgaagtcg
    23281 acgacgtgcc ggcaggtcat gaggaccatc gcgccgagcg cgagcgccca tacgtcgtcg
    23341 tggccgccgc cccgggaggc gcccagggcc aggcccgcgt agaaggcgta ctccttggcg
    23401 cggtcgaacg tggcgtcgag ccaggctccc agcgtggagt actggaggga gtagcgggcg
    23461 agctggccgt cggtgcagtc gaggacgaag gagaagagga gcagcgcgcc ggcggcgacg
    23521 aagccgcccc gggtgccggt ggccgcgcag ccggccgcga tcagcgccgt gagcagcgag
    23581 gcggtcgtca cctgattggg ggtgaggccg cggcgggcgc accagcgggc gaggtagcgg
    23641 gagtacgggc tgatgcagaa ggtggtgaag aagccgtcgc gggacttcac ggcgttgcgc
    23701 aggcgtacgg cctcgtcgtc gacggcgccg acctcggcga gggtcttcgc gcgcgcctcg
    23761 tccccgtgcg gcacggccgc gacgagcacg ccgagctcgg gccggtgcac ggcgacgccg
    23821 tcggcctcca gccgggcggc gacggcgccg gggagctccg cggcgggccc gtgcggcccg
    23881 gacgggtggt ggccgggctc ttcggagtcg ttgtccggag ccgcgtccgg tccggtggcc
    23941 cgtgccgggc ggccggtcgt cacggtgccg agcgcgcgcg tcagggacgc gcgggcgtcc
    24001 ggctgcgcgg tgagcgcgcc ctcgacggcg gcggccggga agcgggggtc ggtcagggcc
    24061 agccgcaggg cgtggacgtg cccgacgaag ccgggatcca ccagagcgac ccgctcggtg
    24121 gccgggacgg cggccagcgc cccggtgacg tccgtcgcca cgcggacgtc gaagccgagg
    24181 gaccgcaggt cctcctcaag ggaggagccg acgggcggcg ggcctgtgag gatggcggtc
    24241 gacagacgaa ctcactcctt gcggctgaca tggccgcctc ggggccgcgg gacgcggcgg
    24301 gcggcagtcg tgcccggacc cgggtgcggg cggcacgtcg gcagaggcta tcggatcacc
    24361 ggaaggtgcc gttcaccgca cgtgcacccc gccttcccgc cactgacagg acgcatggga
    24421 cgcccaggag gttccgggcg cactggagtg aagggaagtg aagagaagtg aagccgacgg
    24481 ggcccttacc ttggctggat tagggtgccg ttatgacatg gctgatcaca ggcggggccg
    24541 ggtacatcgg ggcgcacgtg gcgcgggcga tggtggcggc gggggagcgg gtcgccgtgc
    24601 tggacgatct gtccaccggc gtggccgggc ggctgcccgg cgagtgcgag ctggtgcggg
    24661 gctcggtcct ggaccgtgag gtgctggact cggcgttcgc ccggctgggt gtcacgggtg
    24721 tggtgcatct cgcggcgaag aagcaggtcg gggagtcggt ggagaagccg ctgctctact
    24781 accgggagaa catgcacggg ctgacggtgc tgctggaggc ggcggtcgcg gcgaacgtcg
    24841 ggagcttcgt cttctcctcc tccgcggcgg tctacggcat gccggacgtg gacctcgtca
    24901 cggagaagac gccgtgcctg ccgatgaacc cgtacgggga gaccaagctg gccggcgagt
    24961 ggctggtccg ggccaccggc tcggcgtacg gcatgtccac cgcctgcctg cgctacttca
    25021 acgtggcggg ggcggccacg cccgagctgg ccgacaccgg ggtctacaac atcatcccga
    25081 tgatgttcga ccggctcggc cggggcgaga gcccgcgcat cttcggcgac gactacgcca
    25141 cccccgacgg cacctgcgtc cgtgactaca tccacatcga ggacctggcc acggcccacc
    25201 tggcggcggc gcggcggctg gccgagcggc cgggctcggg ggacctcacg ctgaacgtcg
    25261 gcaccgggca cggggtgtcc gtccgcgaga tggcggacct gatcgcggag gtcaccgggc
    25321 accacagccc cgcgcccgtc gtcgagccac gccgtccggg tgatccggcg cgtgtcgtcg
    25381 cgtcgaacga actgatcgcc cgggagctcg gctggagccc ggcgcacgac gtgcggggca
    25441 tggtgagttc ggcctgggaa ggctggtgcc accaccaccc cggggctcgg gtcccggcat
    25501 aaccacagat cagcgcgtcg gggcatcgtc gcaggtcaga gcagatgaca acggtgttca
    25561 gtgccgcgtt gccccatacc ccccacccgt agttcactga agcctcggcc ggcacccgcc
    25621 ggccggggct caccggttcg ggaggcggca ttcatgggcg cagggcacga ccacggccat
    25681 tcgcacggag gccccccgcc gggcgccggc ggcacggcgg ccgcggccta ccggggccgg
    25741 ctgcggatcg cgctggggat caccctcacg gtgctcgccg cggagatcgt cggcagcgcg
    25801 ctgacgggtt cgctggcgct gctcgccgac gccgggcaca tggcgacgga cgcggtcggg
    25861 gtgggcatgg cgctggtggc gatccacttc gccaaccgcc cggccggcgg tcgccggacg
    25921 tacggctacg cccgcgccga gatcctggcg gcgctgctga actgtctgct gctgctcggt
    25981 gtgggcggct tcatcctcgt cgaggcgatc gagcggctgg cgaaccccac cgaggtgccg
    26041 ggcggcatga ccgtggtctt cggtctggtg ggtgtggtcg ccaatctgat ctccctgggc
    26101 ctgctgatgc gggggcagaa ggagagcctc aatgtgcgcg gggcgttcct ggaggtcctc
    26161 tcggacgcgc tgggctcgct ggccgtggtg gtctcggcgc tggtgatcat ggcgacgggc
    26221 tggacacagg cggacccggt cgcctcgctg ctgatcggcc tgatgatcgt cccgcggacg
    26281 gtcaagctgt tccgggaggc gctggacgtc ctgctggagg cggccccgag gaacgtcgac
    26341 atagacgaga tccggtcaca catcatggcg ctgcccggcg tggaggacct gcacgacctg
    26401 catgtgtgga cgatcacatc cgggatgccc gtcctgtcgg cgcacgtggt cgtcgaccac
    26461 gcggcgctgg actcggtcgg ccacgagaaa atgctgcacg acctgcaagg ctgcctcggc
    26521 gagcacttcg acgtggagca ctgcaccttc cagctggagc ccggtggcca cgcggagcac
    26581 gaggccagac tctgtcattg acgccgggcc gcggtacggc agacttgagg gtcgacgacc
    26641 gacaacgagg atggt
//
