LOCUS       NZ_CP021744            22455 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces albireticuli strain MDJK11 chromosome, complete genome.
ACCESSION   NZ_CP021744
VERSION     NZ_CP021744.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces albireticuli
  ORGANISM  Streptomyces albireticuli
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8144417)
  AUTHORS   Wang,Y., Du,B., Ding,Y., Liu,H., Hou,Q., Liu,K., Yao,L. and Wang,C.
  TITLE     Streptomyces albireticuli Genome sequencing and assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8144417)
  AUTHORS   Wang,Y., Du,B., Ding,Y., Liu,H., Hou,Q., Liu,K., Yao,L. and Wang,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2017) Department of Mcrobiology, Shandong
            Agricultural University, No.61 Daizong Street, Taian, Shandong
            271018, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 2.3
            Expected Final Version            :: yes
            Genome Coverage                   :: 88.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 07:12:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,975
            CDSs (total)                      :: 6,876
            Genes (coding)                    :: 6,711
            CDSs (with protein)               :: 6,711
            Genes (RNA)                       :: 99
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 75
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 165
            CDSs (without protein)            :: 165
            Pseudo Genes (ambiguous residues) :: 0 of 165
            Pseudo Genes (frameshifted)       :: 74 of 165
            Pseudo Genes (incomplete)         :: 97 of 165
            Pseudo Genes (internal stop)      :: 5 of 165
            Pseudo Genes (multiple problems)  :: 9 of 165
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:17:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 91707
            Orig. end                         :: 114162
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP021744.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22455
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="2"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22455
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22455
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12455](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12455
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(1222..1237)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.32"
                     /tool="antismash"
     misc_feature    complement(1701..1712)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            2090..2566
                     /locus_tag="SMD11_RS00440"
                     /old_locus_tag="SMD11_0094"
     CDS             2090..2566
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950289.1"
                     /locus_tag="SMD11_RS00440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0094"
                     /product="hypothetical protein"
                     /protein_id="WP_087924489.1"
                     /transl_table=11
                     /translation="MEAVAASVIAVLGTLLGAGITHAFQQRATARGERSARQERLRQER
                     FDAYCSYAGALVNYRRSLIHRWHCEHEDPPPDDVAEARRRSYELRSEAQEALFRVQMLT
                     DDEALTALAWRAFERVGKLHQIDSREELEGRRQEARELIEELVNAARQHVRARV"
     gene            complement(2713..3213)
                     /locus_tag="SMD11_RS00445"
                     /old_locus_tag="SMD11_0095"
     CDS             complement(2713..3213)
                     /EC_number="3.5.4.33"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0052717 - tRNA-specific adenosine-34
                     deaminase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1240: riboflavin biosynthesis protein RibD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523437.1"
                     /locus_tag="SMD11_RS00445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0095"
                     /product="nucleoside deaminase"
                     /protein_id="WP_087924490.1"
                     /transl_table=11
                     /translation="MDFIQRTIDLARRNVEEGGRPFATVIVKDGRVLAESPNLVAQTSD
                     PTAHAEILAIREACTRLGTEHLTGTTIYVLAHPCPMCLGSLYYASPDEVVFLTGRDDYA
                     PHYVDDRKYFELGTFYAEFAKDFTDRRLPMRHEPRAAATDVYRAWQERNNGERRVAGAP
                     TAA"
     gene            complement(3307..3777)
                     /gene="cynS"
                     /locus_tag="SMD11_RS00450"
                     /old_locus_tag="SMD11_0096"
     CDS             complement(3307..3777)
                     /EC_number="4.2.1.104"
                     /GO_function="GO:0008824 - cyanate hydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009636 - response to toxic substance
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cynS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140951.1"
                     /locus_tag="SMD11_RS00450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0096"
                     /product="cyanase"
                     /protein_id="WP_087924491.1"
                     /transl_table=11
                     /translation="MIHAQFDATAREQLAAQAVAAKTAKDLSWQEVADAAGLSVAFVTA
                     AVLGQHPLPEASAKAVAALLGLDDDAAALLQAIPTRGSIPGGIPTDPTIYRFYEMLQVY
                     GTTLKALVHEQFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF"
     gene            complement(3880..4494)
                     /locus_tag="SMD11_RS00455"
                     /old_locus_tag="SMD11_0097"
     CDS             complement(3880..4494)
                     /GO_function="GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670186.1"
                     /locus_tag="SMD11_RS00455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0097"
                     /product="carbonic anhydrase"
                     /protein_id="WP_087930202.1"
                     /transl_table=11
                     /translation="MHHLAEGVHSFQRDVFPARAELFAHLATTHRPGTLFISCSDARVV
                     PELITQREPGELFVIRTAGNLVPAHTPAADAVAASIEYAVTVLGVSDVIVCGHSACGAM
                     TALADGHDLTAVPAVADWLRHADAARARTTAHDAQEAGDKVAALVRDNVLAQLANLATH
                     PSVARALARRELTLHGWVYDIGSGTVEELDAASGRFTALAA"
     misc_feature    complement(4564..4579)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.44"
                     /tool="antismash"
     gene            4671..5657
                     /gene="cynR"
                     /locus_tag="SMD11_RS00460"
                     /old_locus_tag="SMD11_0098"
     CDS             4671..5657
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="cynR"
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018566757.1"
                     /locus_tag="SMD11_RS00460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0098"
                     /product="transcriptional regulator CynR"
                     /protein_id="WP_087924492.1"
                     /transl_table=11
                     /translation="MELRHLRYLLAVAEHASFTRAAEALHISQPTLSQQVRQLERALKT
                     QLLDRTGRTVRLTDAGRAYAHYARAALQDLAAAERAVLDVRDLSVGALRLAMTPTFTAY
                     LIGPLVARFHARHPGITLEVRELTQDRIESALLADEVDLGIAFSGAHLPGVEGVALFTE
                     TLSLVVGPRHPRAGGAEPVTAEDPEQERETERGPVVELPVRELGGHQLALLSGDFATRG
                     HIDAYFAGQGVQPPIAVEANSINALTEIVQRTALATVLPDAITRGHPALRPVPLVPPLP
                     ARTVALLRRESAYRSAAAAAFATLAREWVREAGWAEPGERGAPGGGG"
     gene            5666..6244
                     /locus_tag="SMD11_RS00465"
                     /old_locus_tag="SMD11_0099"
     CDS             5666..6244
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS00465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_0099"
                     /product="hypothetical protein"
                     /protein_id="WP_159395153.1"
                     /transl_table=11
                     /translation="MRANGTGEVVWTPAALVVGGAALLAEAAVAVMALWAWGMTHPHPE
                     GEDGGALFVLVLPLLLALLGVVALVLAAALVLPALALARRAGGRWGRKGAWWWPVAACP
                     AVAAAAVAGGGAVAAALGGTGAPAVYGWWWLVLSAALAAAALPARAANQRVARGRPVLR
                     VLLAGCAGVAGVTAVAGLAAVLVVGAVLA"
     gene            complement(6315..6710)
                     /locus_tag="SMD11_RS36085"
                     /old_locus_tag="SMD11_0100"
     CDS             complement(6315..6710)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS36085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_0100"
                     /product="hypothetical protein"
                     /protein_id="WP_234365818.1"
                     /transl_table=11
                     /translation="MSIAWREQDDWLRTGARTVLDQLREPGHTEQYQGEKIDWSSLRVW
                     LAATGSRLTMTQLQADVLGLGHSTRDSAAVVHKDGRILADSASLTVLRGWLAAWEDAGR
                     PAPDSYTPALDPGMDSDVPGWDLRLTR"
     gene            6861..7202
                     /locus_tag="SMD11_RS36090"
                     /old_locus_tag="SMD11_0101"
     CDS             6861..7202
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS36090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_0101"
                     /product="hypothetical protein"
                     /protein_id="WP_234365819.1"
                     /transl_table=11
                     /translation="MARLGTAATGSVATIRPPSTVWSTHAFGSRGGVHQAPRRSYGPRS
                     GCPAVPSVVKQRMLFSPRSAWMRLAQQVRNGSMSRLVTDPVGPTSPASRPPVRPVPTSP
                     TFMPGRTSR"
     gene            7667..8410
                     /locus_tag="SMD11_RS00480"
                     /old_locus_tag="SMD11_0102"
     CDS             7667..8410
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639741.1"
                     /locus_tag="SMD11_RS00480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0102"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_234365820.1"
                     /transl_table=11
                     /translation="MRRARTARNLTLEEAADNLNEITGGATDASLLSAWETGRRRTGAK
                     NRAGLCQLYRERPEVLFAHQDGEATSVLETSGTAVVVKVLTRWTDLIEAMVSVASSARE
                     QLVVTGSRSREKAYLAAIETAVAQHPDLVHYRVLYGPPRHRTLADHLVRLLELRDPTAR
                     RNGVKTLHIGMVEPAAALERFFVASETQAVVPLPSFHGAEGFDCGVLLSREAAVGLVHH
                     GREACASARPVETIEAVRALPVRHN"
     misc_feature    8294..8296
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(8415..8430)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.67"
                     /tool="antismash"
     gene            8426..9610
                     /locus_tag="SMD11_RS00485"
                     /old_locus_tag="SMD11_0103"
     CDS             8426..9610
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639740.1"
                     /locus_tag="SMD11_RS00485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0103"
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="WP_087924496.1"
                     /transl_table=11
                     /translation="MSENLQQARMASVIELAQELIRRPSRGGIDNYGPVLGVLEDWLND
                     RAVPHRRLYGDAGELVGLLVEISGGRPGQWWTLDACVDTAPYGDENAWSFPPASGDVVD
                     GWLLGRGAADSKLAVAMFCHIADDLMPRAADLNGGLAMLLDVDEHTGGFGGARAYLADP
                     RAARPAGVMIGYPGLDEVVVGGRGLWRATLAVHAPSGHSGSSKTVVGAITRAAHLVRLL
                     DEAELPGVDGASGFPLPPKLSVTSVHGGQGFSVTPDRCELNVDVRTTPGFDAHDAETLV
                     RKAVAELDAELPAPASTEVTPVAAWPPFRLAEDEQPAAALLGAAAEMGLAVKAKTAGPS
                     NIGNLLAGEGIPATAGFGVPYEGLHGIDERAHLAELPQVYAVYQRAVLNLLKAG"
     misc_feature    9634..9647
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.82"
                     /tool="antismash"
     misc_feature    complement(9676..9690)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.7"
                     /tool="antismash"
     misc_feature    complement(9677..9690)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.64"
                     /tool="antismash"
     gene            9751..9912
                     /locus_tag="SMD11_RS35185"
                     /old_locus_tag="SMD11_0104"
     CDS             9751..9912
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS35185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_0104"
                     /product="hypothetical protein"
                     /protein_id="WP_159395154.1"
                     /transl_table=11
                     /translation="MAEQTVTIKPVEDKPAATPRVTFAPQISTHPVATLTLGRQTFNDS
                     DKDNYFEG"
     misc_feature    9772..9786
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            10001..11752
                     /locus_tag="SMD11_RS00490"
                     /old_locus_tag="SMD11_0105"
     CDS             10001..11752
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="SMD11_RS00490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0105"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_087924497.1"
                     /sec_met_domain="Asn_synthase (E-value: 6.5e-26, bitscore:
                     90.4, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQEWLTGGTAAVDGVVIEGLGDLRRAPGTRVQVACEGPVGLVVV
                     GDCPVTQEELRAALPATRVGQWAGLTRWPGSYWVVADNGRQRFVCGDLAGSRAVYYTLR
                     GNEAAWASQARLLEQDRRLTPDLPLVAARLTVGEHHWPHRTPYEQIRVVPGGFGLLLAP
                     EAPPQLVDVNGVDPVDELREGAVRFGQALTNAVQHRVRVSGGAVGADLSGGLDSSAAVV
                     LAADAGTVHAVTYTDGYTSGEDMAFASRIAEHTGARHTVATGGDEQLPFGFPAGQPSEA
                     EPVLAAAMYAMDAAYLRPVQGLPLHLTGHGGDIVLDASSSCWVRLLQDGHRREAHRQVA
                     AFARLRNTAPGPYWKALKHAADLGRSGALERAAETLEHGPVTPQTTVAGWSWCRLGAGA
                     SWLTADGRHQVAALLRQAAGDQQPELADEFDQWAALRSVGTSARGWAPYGHALGIRPVY
                     PYLDNQVVRAAFGVPALARRGLVAYKPLLRAALPELPDWLTSRRSKGSFTAQRIAGLAR
                     HRDRLDELTASSPLAAAGLIDPAAVRTSLAQTARGQSATVIADLHQLIVTCWWLSGQTT
                     RREVAAC"
     gene            11746..12042
                     /locus_tag="SMD11_RS00495"
                     /old_locus_tag="SMD11_0106"
     CDS             11746..12042
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS00495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_0106"
                     /product="PqqD family protein"
                     /protein_id="WP_087924498.1"
                     /transl_table=11
                     /translation="MLIPALHVHHNTGPDGTAVIDVKRETWLMLDQDASRIWHAITVRG
                     GTARLADEIAVPTGQDPQQVSGQIVAFVDDLVAAGVLVDTDRPRRARRKRWRR"
     gene            12039..12455
                     /locus_tag="SMD11_RS00500"
                     /old_locus_tag="SMD11_0107"
     CDS             12039..12455
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024862.4"
                     /locus_tag="SMD11_RS00500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0107"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_107421912.1"
                     /sec_met_domain="PF13471 (E-value: 2.2e-07, bitscore: 29.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVMVPTARPTAPWRDRLVAALALALSLAVSPLPLRWKLAAVRLL
                     RGLPYARLARLEALYTAVQAVIPSWWPGRIACAEISLATVIATALTCRQARWVHGARFM
                     PHAAHAWAEVPEGAVGRDIGDAVDRPWMPVLAEP"
     gene            12640..14520
                     /locus_tag="SMD11_RS00505"
                     /old_locus_tag="SMD11_0108"
     CDS             12640..14520
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639709.1"
                     /locus_tag="SMD11_RS00505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0108"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_234365821.1"
                     /transl_table=11
                     /translation="MSSSVSSPPVAAAGQPPVMCLASDRHFEASVNLSTWAIARRLPHT
                     LAEAARLGWRTDRRAVLALLICQIGAAALTATALAATTRVLATVFTGGDIAAGLRENLT
                     TVVVLTLAASGRYLLDAAARASAARLAPKAVREADLEVITTATAAELVAYENPDFEDAH
                     AAASDGAEKTGDLILDAQLLTSAAARMAAAATVVTLLHPVMLPLLVLSVVPCAWGAVRG
                     ARIEHAAHHRNLADSRLRNVFRSYTTERNTADEVRAGTMAAFLIRQYRVVSGRLEAEQL
                     KATRQALVVQGIGDALTAVGTAATWGVLVLLVASGRMELAVAGTAALAVRTSMAALATT
                     VRAGARLFRTSLSLDDWARFLAVAKPWTTRRGSVPIAEDGPLVITAMDVSFTYPGARAP
                     ALDGINLDLKRGEVIALVGENGAGKSTLARILTGLFLPTSGSVRWDGVDLADADPAGVL
                     AKVALVPQDYTRWPLAARENITLGQPRPDGDAAVRAAAEAAGADTVIAALPHGLDTSLA
                     RSWWGGHDLSGGQWQRVAVARAFHRDAPVLVMDEPTAALDARAEHRIYTRLRALAEGRA
                     TVFVTHRLANTRLADRIIVLNHGRIEQMGAYDELAHQGLFHELLKLQEDR"
     gene            complement(15109..15555)
                     /locus_tag="SMD11_RS00510"
                     /old_locus_tag="SMD11_0109"
     CDS             complement(15109..15555)
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044164.1"
                     /locus_tag="SMD11_RS00510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0109"
                     /product="protein-tyrosine phosphatase family protein"
                     /protein_id="WP_087924499.1"
                     /transl_table=11
                     /translation="MSGLWNPDTPGVLRLPSGRLVRGRGLRRPLPDGPAPAYAVHLLGT
                     RPPEVPWEARWLRWPDFRLPADPADARTVLREVWERAAGERVEVACGGGRGRTGTALAC
                     LAVLDGVPPGRAVEFVRRHYDRHAVETPWQKRYVRRFPGGPGGR"
     gene            complement(15552..15758)
                     /locus_tag="SMD11_RS00515"
                     /old_locus_tag="SMD11_0110"
     CDS             complement(15552..15758)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="SMD11_RS00515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0110"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_199843771.1"
                     /transl_table=11
                     /translation="MTPQEPGDPLRALRLRQGLSQAGLAGVTHSVVSRLEAGRHSPTVR
                     SLSRPAEALGAGLVLDLTPPEPR"
     gene            complement(15948..16604)
                     /locus_tag="SMD11_RS00520"
                     /old_locus_tag="SMD11_0111"
     CDS             complement(15948..16604)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016470408.1"
                     /locus_tag="SMD11_RS00520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0111"
                     /product="response regulator transcription factor"
                     /protein_id="WP_087924501.1"
                     /transl_table=11
                     /translation="MRIVIAEDLYLLRDGMVRLIAAYGHQVVATAATGPETLDALLTWR
                     PDVAVVDVRMPPTGTDEGLRAALAARTELPGLPVLILSQYVEQLYARELLADGTGGIGY
                     FLKESVFDADQFIDALARVAAGGTAMDPAVIAGLLSSGTSHRRLGQLTEREHSVLALMA
                     EGLSNQAISRRLYLSESAISKYTTSLFGKLGITDDDSGNRRVLAVLTYLNNPNNP"
     gene            complement(16589..17848)
                     /locus_tag="SMD11_RS00525"
                     /old_locus_tag="SMD11_0112"
     CDS             complement(16589..17848)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009074516.1"
                     /locus_tag="SMD11_RS00525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0112"
                     /product="histidine kinase"
                     /protein_id="WP_087924502.1"
                     /transl_table=11
                     /translation="MRELGSWAGRAGAGFVRACAVAALSMLVPAVWAGAVALGIRWGAA
                     NPWSWTAPLVLACTGTLALSRPLCRAVRFLVRTWTATVLPAGYRRAGPVTRMSTGQWWN
                     GFSYERTRRDALRDQKWRLRWCDPATWRDLRFTVIVPFTAGVAAAVPPAGAAVAVLWLG
                     RPAPAARLAGALGLAAALAGAPYAWRVLPVVAARFLRPSRAMVLAGRVQELTAQRADAT
                     LAQAAEIRRIERDLHDGAQARLVGLGLSLATAERLMESDPARARALMRDARAGAATSLT
                     ELRELVRGINPPVLSDRGLLDAVRALALDSPLEATVTAGGHLRLEAPVESALYFATAEL
                     LTNAARHAGATRARISLAHDGTHLVVEVEDDGHGGAAERPGGGLAGLRRRLAVFDGHLE
                     ITSPAGGPTHVRILVPCASS"
     misc_feature    17864..17879
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.93"
                     /tool="antismash"
     gene            18014..18454
                     /locus_tag="SMD11_RS00530"
                     /old_locus_tag="SMD11_0113"
     CDS             18014..18454
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016470406.1"
                     /locus_tag="SMD11_RS00530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0113"
                     /product="hypothetical protein"
                     /protein_id="WP_234365822.1"
                     /transl_table=11
                     /translation="METDTHTTAGTSLPGDSRAQEALGAARNSIRLYGGLGALALLAVV
                     AVAGSGCAVNTFMGVRAVLLPVAAVLLHRLATAASRGSRRAYERVRALTVILPVAIVGV
                     DLIPGICPPWYAVTQAVCMVPVVRAAVLLRGRAPRAAFAKGR"
     gene            complement(18622..18819)
                     /locus_tag="SMD11_RS00535"
                     /old_locus_tag="SMD11_0114"
     CDS             complement(18622..18819)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019074638.1"
                     /locus_tag="SMD11_RS00535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0114"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_087924503.1"
                     /transl_table=11
                     /translation="MAADLVRARRVQLGMSQAELAARAGTGQAFVSRVESGKTIPTLPV
                     LQRLATALECDVALDFLPHR"
     gene            complement(18819..19403)
                     /locus_tag="SMD11_RS00540"
                     /old_locus_tag="SMD11_0115"
     CDS             complement(18819..19403)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004937717.1"
                     /locus_tag="SMD11_RS00540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMD11_0115"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_087924504.1"
                     /transl_table=11
                     /translation="MTADAKREIYRHLRALVEHFTPPAPFSPHVEISDGQLVMMMSPAG
                     RHDLAALRIERQLQPQLPAGVVATTSGDIEEADLGQLRRPDVLVLPEAAMDTDDAISPH
                     ALLAAVEIVSLSNPENDYDSKLRHYPQLGIPHYLIVDPRDGTCVHYWAIGDKGGTPVYE
                     GRAPYVFGDKIPFGDWVIDTAELPRYSRSSG"
     gene            complement(19474..20586)
                     /locus_tag="SMD11_RS35190"
     CDS             complement(19474..20586)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS35190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_159395155.1"
                     /transl_table=11
                     /translation="MTTPPAPDPETDPETDTETALHRFHALLTQDDTARATDHHLRTHQ
                     HAMGLTFHGHPLRPLLRPRLISATDHARVRAEGATLALDRLASHALYPGEEGDLVRAHL
                     ALTPQEAALAALVPPAGPLSPHSRLDGFRAGGRTAFVECNAHSPAGIRHPGPARRRLEG
                     HRGDGGVRPLRARPGRTPADPRLGRRGVRDGQPLHQPPGAQEVGPGPAHRPGRRRAAAP
                     FRGGRRPGPGALDPAVRAGPTTCPEGRRTGLLDLARARRAHLVLKPNDDYGGKGVLCGW
                     ETTDQAWHSALGRALLTPHVLQERVPLPTAPYPDLAGGRLRVREYAESTDPFLFGTDSP
                     GCICRLSRTSLLNVSTGAAPVPVFLITPSS"
     gene            complement(20583..21023)
                     /locus_tag="SMD11_RS35195"
                     /old_locus_tag="SMD11_0117"
     CDS             complement(20583..21023)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMD11_RS35195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMD11_0117"
                     /product="hypothetical protein"
                     /protein_id="WP_159395156.1"
                     /transl_table=11
                     /translation="MSPSVIHRGKDDTMGPHEHPAHPAAEALGPLYPVAKEAADRLQLG
                     MSVKEAIEEARTAVPGGVGFTPQQVVQGAHDLLTAGPDEDLEEIPGEDPHHHQDHNHHQ
                     DHNQGQAQDQDQERNRARHAGRDQAPDGPTGQPDHPGRPRPQ"
     misc_feature    complement(21346..21360)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    complement(21877..21890)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.41"
                     /tool="antismash"
ORIGIN
        1 ccgtcggggt ccagggtgcg gaaggggcgg gcggtgacgg ccactccccc ggtgacgtac
       61 ctcctcgtcc tgtccccggt gcccgcgggg gtggtgggga gggtgaaggg ggtgagccgg
      121 cgccggtcct tcaggtgggc caggacgggg ctggtggtgc gggcgaggtc gacggcgggg
      181 aggcgggcgt ccaggagggc ggtggcgtgc caggtgtggc cggggacggc ggagtgtgcg
      241 gtgaagcggc cgctgccggg gtcgggggtg acggtgaagc gggggccggc gacctcggcg
      301 atgccggcgt cgaggagggc caccagttcc tcgatgcgcg tccagggcgg tcccagggag
      361 aggaaggcgt gcagcggggt gaaccagccg cgcacgtcgg tgcggtagga ctcgccctcg
      421 atgccgccgt cgttgatcac cgcgcggatc tcgttgcgga tgtcgcgcag gacgtccagg
      481 gcggacttca gggcgctggt gaggttgccc cggcgggcct cggccacgtc cgccagcagg
      541 tgggcgcgca ggaaggtgtg ccaggcgggc ggggaggcca gggcggtggc atcccagggg
      601 cgggccgtct tcgcccagtc ccaccggtgg tgctcgggca ggtggaactt gcgcaggatc
      661 tggcgttcgg cgtcaccgga ccagggggcg gtgacgtaga gggcgtggaa ttcctgggcg
      721 gtggccggtg aggcggcctc ggccaccagg cgggtgtagt agacggtttc gacctccttg
      781 gcgatcagcg gccagcagtc gcggcggaag tccagtcccc cggcggggcg tgcccgttcc
      841 cgtaaggcgt cgacggcggc cgtggtgagg aagaccggtt cgtggcggcc gtcgcccttc
      901 tcgttgtccg cccgcccgtg cagggggatg ccccggcgtg acccgcagac caggcggggt
      961 tcgtccccgg agggcaggta gcgcaggcgg ccgccggcct cccgggtgaa ggtgccgccc
     1021 cggccggtgg tgagcagggc catgtggtcg aagaaggaca ggccgagtcc gcggacgagg
     1081 acggggcggc ccggttcgag ggcgtccagg tcggtgtcgg cggggctggc gggccgctgg
     1141 tagcgcccgc cggtacgggc ggcgaagcgg gcgagcgccg cttcctcgcc ggtggggtgc
     1201 acgccggtgt ggccggtggc caggaccagc tggtcgacgt cgaaggtgcg gcccttctcg
     1261 caggtcaggc gctggcgccc ctggggggtg tcggtgacgg cgacgatacg ggtgtggtgg
     1321 ccgcgcacgg tcaggcgggc gggggcgcgg cgcaggacct cgcggtgggc ccattcgagg
     1381 tagtggccgt agaaggagcg gcggcagtag ctgccggggc cggtgcggcg ggcctggtcg
     1441 aggacctcgg gcgggtagcg gccgggtatg cggccggccg ccagtgccac ggcccacccg
     1501 tacaggctcg gtcccgggcg gacggggccg gacatcggca cggtgtcgtc ggcgaacgcg
     1561 gtgatctggg aggcgacgat gttcatgatc agggcgggtg gctggtcggt gcgccagacc
     1621 tggccggagc cgaagccgcg gggctcgaac agctcgacga cggccggggg gccggggtgg
     1681 gcgcgggcat tggcgacgag gcgttcgagt acggacagcc cgcgggggcc gactccgact
     1741 atgccgatcc tgagcaccgc cgtctgcttc ctcgtcgtcc tcgtgtttct ctgttcgctc
     1801 tgcttttctt ctgtgccggg cggccgccgg aacgggcgca cggcaggggc acacctgtcg
     1861 cgcgcggcgg ccgggcgggg ccgggcatgg cgtggactct aggagaagat ctcgccgggg
     1921 aaggggagat tgggggaatc tcctgcgcgg cgcggcccgc gcggcctgtg cgggcccggt
     1981 gtcccgggcg gccccgcggc atcccgggag aggcaggggg cggtggggtg tgtggggttg
     2041 gccgggaaaa gtgtgccgtg cggggcgggt ggtgtgatca ggtggcgggg tggaagccgt
     2101 cgccgccagt gtcatagccg tgctcgggac gttgctgggc gcggggatca cccacgcctt
     2161 ccagcagcgg gcgaccgcgc gcggcgagcg ttccgcccgc caggagcggc tgcgccagga
     2221 gaggttcgac gcctactgct cgtacgcggg cgccctggtc aactaccggc gcagcctcat
     2281 ccaccgctgg cactgcgagc acgaggatcc gccgccggac gacgtggcgg aggcccgccg
     2341 ccgctcctac gagctgcgct ccgaggcgca ggaggccctt ttccgggtgc agatgcttac
     2401 cgacgacgag gcgttgaccg ccctggcgtg gcgggcgttc gagcgggtcg gcaagctcca
     2461 ccagatcgac agccgggagg aactggaggg gcggcggcaa gaggcccggg agctgatcga
     2521 ggagctggtg aacgcggccc ggcagcatgt gcgggcacgg gtgtgaggct gctgccgggc
     2581 gcgttccctt gtccggcttc ccgccggttc ccggcttact cctgccggct cccgccgatc
     2641 gctgctgatc gccatcgatc gccattgatc gctgctgatc gccgctggtg cgcggggcgg
     2701 gtgtgcgggt ggtcaggcgg cggtgggggc gcccgcgacg cggcgctcgc cgttgttgcg
     2761 ctcctgccag gcgcggtaga cgtcggtggc ggcggcgcgg ggctcgtggc gcatggggag
     2821 ccggcggtcg gtgaagtcct tggcgaactc ggcgtagaag gtgccgagtt cgaagtactt
     2881 gcggtcgtcc acgtagtggg gggcgtagtc gtcgcggccg gtgaggaaga cgacctcgtc
     2941 ggggctggcg tagtagaggg agcccaggca catcgggcag gggtgggcga gcacgtagat
     3001 ggtggtgccg gtcaggtgct cggtgcccag gcgggtgcag gcctcgcgga tggcgaggat
     3061 ctcggcgtgg gcggtggggt cgctggtctg ggcgacgagg ttggggctct cggcgaggac
     3121 gcggccgtcc ttgacgatga cggtcgcgaa ggggcggccg ccttcctcga cgttgcggcg
     3181 ggcgaggtcg atggtgcgct ggatgaagtc cacaggaggc tccccgggtg gtgcggcggt
     3241 gcggaaggaa aggggggcgg gcgggccggc ggcccgcccg cctttgtgtc cggtgcgggg
     3301 ggtgggtcag aagggcttgg tgggcaggta cttgccgtcc agggtgatca cggcgcgctc
     3361 gccgccctcg gggtcggcga ccttcttcac gtccagcttg aagttgatcg cgctgatgat
     3421 gccgtcaccg aactgctcgt ggaccagggc cttgagggtg gtgccgtaga cctggagcat
     3481 ctcgtagaag cggtagatgg tcgggtcggt ggggatgccg ccggggatgg agccgcgggt
     3541 cgggatcgcc tggagcaggg ccgcggcgtc gtcgtccagg cccagcaggg cggcgacggc
     3601 cttggcggag gcctcgggca gggggtgctg gccgaggacg gcggcggtga cgaaggcgac
     3661 ggacaggccg gcggcgtcgg ccacctcctg ccaggagagg tccttggcgg tcttggccgc
     3721 gacggcctgg gcggcgagct gctcgcgggc ggtggcgtcg aactgggcgt ggatcatggg
     3781 aaaggggtcc tttcgggtac gggcgctccc gccccggcgg ggtgccgggg cgcacggggg
     3841 cgccgctgtg ggttcggggt gggtggttcg gggggtgggt caggcggcga gggcggtgaa
     3901 gcggccgctc gcggcgtcga gttcctcgac ggtgccggag ccgatgtcgt agacccagcc
     3961 gtgcagggtc agctcgcggc gggccagggc gcgggcgacg ctggggtggg tggcgaggtt
     4021 cgccagctgg gccaggacgt tgtcgcggac gagcgcggcg accttgtccc cggcctcctg
     4081 ggcgtcgtgg gcggtggtgc gggcgcgggc ggcgtcggcg tggcgcagcc agtcggcgac
     4141 ggcgggcacg gcggtgaggt cgtggccgtc ggcgagggcg gtcatggccc cgcaggcgga
     4201 gtggccgcag acgatgacgt cgctgacgcc caggacggtg acggcgtact cgatgctcgc
     4261 cgcgaccgcg tcggcggcgg gggtgtgcgc ggggacgagg ttgccggcgg tgcggatgac
     4321 gaacagctcg cccggctcgc gctgggtgat cagctcgggt acgacgcggg cgtcggagca
     4381 gctgatgaac agggtgccgg ggcggtgggt ggtggcgagg tgcgcgaaga gctccgcgcg
     4441 ggcggggaag acgtcccgct ggaagctgtg gactccctcg gcgaggtggt gcatggtcac
     4501 tcccttgtgg gtggtgtgtc ggtgggggcc gacgtcgtcc actgtgcatg acctgtgctt
     4561 atagtgtcca agtcgtgaaa ggcatgactt ctattggtcg tgtctatagg tgcacgggcc
     4621 gggtgcggga gcccgggggc gtgcggggtg tgggggtgtg gaggcaggtc atggaactgc
     4681 gtcatctgcg gtatctgctc gcggtcgccg agcacgcgag tttcacccgg gccgccgagg
     4741 ccctgcacat ctcgcagccc acgctctccc agcaggtcag gcagctggag cgggccctga
     4801 agacacagct gctggaccgc accgggcgca cggtgcggct gaccgacgcg ggccgggcct
     4861 acgcgcacta cgcgcgggcc gccctccagg acctggccgc ggccgaacgc gccgtgctgg
     4921 acgtgcggga cctgagcgtg ggggcgctgc ggctggcgat gacgccgacg ttcaccgcgt
     4981 acctgatcgg cccgctggtg gcgcggttcc acgcccggca cccggggatc accctggagg
     5041 tgcgggagct gacgcaggac cgcatcgagt ccgcgctgct ggccgacgag gtggacctgg
     5101 ggatcgcgtt cagcggggcg cacctgccgg gggtggaggg ggtggcgctg ttcaccgaga
     5161 cgctgagcct ggtggtgggg ccgcgccacc cgcgggcggg cggggcggag ccggtgacgg
     5221 cggaggaccc ggagcaggag cgggagacag agcggggccc ggtggtggag ctgccggtgc
     5281 gggagctcgg cggtcatcaa ctggcgctgc tcagcgggga tttcgccacc cgcgggcaca
     5341 tcgacgccta cttcgccggg cagggggtgc agccgcctat cgcggtggag gccaattcca
     5401 tcaacgcgct gaccgagatc gtccagcgca ccgccctggc caccgtgctg cccgacgcca
     5461 tcacccgcgg ccacccggcg ctgcgccccg tgccgctggt gccgccgctg cccgcccgga
     5521 cggtggcgct gctgcgccgg gagagcgcgt accgcagcgc cgcggccgcc gcgttcgcca
     5581 ccctggcccg tgagtgggtg cgggaggcgg ggtgggcgga acccggggag cggggcgcgc
     5641 ccggcggcgg gggatgatcg cgggcgtgag agcgaacggg acaggtgagg tggtgtggac
     5701 gccggccgcg ctggtggtgg ggggtgccgc gctgctggcc gaggcggccg tggcggtgat
     5761 ggccctgtgg gcgtggggga tgacgcaccc gcaccccgaa ggggaggacg gcggggcgct
     5821 gttcgtcctg gtcctgcccc tcctgctggc cctgctgggg gtggtggccc tggtcctggc
     5881 cgcggcgctc gtgctgcccg cgctcgccct ggcccggcgg gcgggcggcc gctggggccg
     5941 caagggggcg tggtggtggc cggtggcagc gtgcccggcc gtcgcggcgg ccgcggtggc
     6001 cggcggcggc gcggtggccg cggcgctggg cgggacgggg gcgccggcgg tgtacggctg
     6061 gtggtggctg gtgctgtcgg ccgcgctcgc cgcggcggcg ctgccggccc gggcggccaa
     6121 ccagcgtgtg gcccgggggc gtccggtgct gcgggtgctg ctggccgggt gcgcgggggt
     6181 ggcgggcgtc acggcggtgg cgggtctggc ggcggtgctg gtggtggggg cggtgctggc
     6241 gtgagggtgc gggcgcggcg gggccgtggc cctggccggc ggcggcgccc gggaccgtcc
     6301 gccggcagcg ggtcctaccg ggtcaggcgg aggtcccagc cagggacgtc gctgtccatg
     6361 ccggggtcca gggccggggt gtaggagtcg ggggcggggc gcccggcgtc ctcccatgcg
     6421 gcgagccagc cccggagcac ggtcagcgac gcggagtcgg cgaggatccg gccgtccttg
     6481 tggaccacgg cggcggagtc gcgggtcgag tggcccaggc cgaggacatc ggcctgaagt
     6541 tgcgtcatcg tcagccggga accggtggcg gccagccaga cgcgcaggct ggaccagtcg
     6601 atcttctcgc cttggtactg ctcggtgtgg ccgggctctc gcagctggtc caggaccgta
     6661 cgggccccgg tgcgaagcca gtcgtcctgc tcgcgccagg cgatcgacac ccacgaggcg
     6721 gccgggacgc ggttctccca gtcgacccac cgggccggga ccgagaagtc ggtccgggca
     6781 gagccggcgg tctcgatgta ggtgccgggg aagatctcct cgacgtgcgg ctgccgtcac
     6841 ggatacggat cctggtgccg atggccaggc tcggcaccgc cgcgaccggc agcgtggcga
     6901 cgatcaggcc gccctcgacg gtctggtcca cccacgcctt cggcagcagg ggcggggtgc
     6961 accaggcgcc gaggcggtcg tacgggcccc gctcggggtg tccggcggtg ccgtccgtgg
     7021 tgaagcagcg gatgttgttc agcccgcgtt cggcgtggat gcggttggcc cagcaggtca
     7081 ggaacgggtc gatgtccagg ctggtgaccg acccggtcgg gccgacgagt ccggcgagca
     7141 ggccgccggt caggccggtg ccgacgtcgc cgaccttcat gcccggccgg acgtcgaggt
     7201 aggtcaggtc ccggtggacg aagacggggt tcgtgcggtg gatggtcggg ccacggtcgc
     7261 cgttgtgggt gtagtgccgc tcagggactt tctcagcggc ggcagcgacg gaagcggcga
     7321 tggcggtggt catcggtgtc actccttcgt ggatgatcgg gacgcgttcc tcaactgctc
     7381 cgagtgggtg agggacacga gtggacgagg cgccaggttg acgcgctcag atgacgagcg
     7441 cggcgtggtg gtgccatccg gcctcaggtg tattcgccga ccgggccgcc attagtgatc
     7501 gagcctcgct cgctgccgtg tgggatgcgc ccagccgtat gcggggatga gtacgagggc
     7561 ggtcgatgaa gggggaacgc gcggtggaat ccatatgtgc tgagccgacc acggatcacc
     7621 aggcgggagg atgactgtgg ccgggctgac aggcggagag tcggcgttga gacgtgcgcg
     7681 tacggcaagg aatctgacgc tggaggaggc cgccgacaac ctgaacgaga tcactggggg
     7741 cgcgacggac gcgagtctgc tcagcgcgtg ggagaccggc cggcgccgga ccggggcgaa
     7801 gaaccgggct gggctgtgcc agctgtaccg ggaacgcccc gaggtgctgt tcgcccacca
     7861 ggacggagag gccaccagcg tgctggagac ctccggcacg gcggtggtcg tcaaggtgct
     7921 cacccgctgg accgacctga tcgaagcgat ggtcagtgtc gcctccagcg cccgcgaaca
     7981 gctggtcgtc accggcagcc ggagccggga gaaggcgtat ctggcggcga tcgaaacggc
     8041 cgtggcccag cacccggacc tggtccacta ccgggtgctc tacggcccac cccggcaccg
     8101 cacgctcgcc gaccacctcg tgcggctgct ggagctgcgc gacccgaccg cccgccgcaa
     8161 cggcgtcaag acgctccaca tcgggatggt cgaaccggca gcagcgctgg aacgcttctt
     8221 cgtggcctcg gagacacaag cggtcgtgcc gctgccgtcc ttccacggcg cggaagggtt
     8281 cgactgcggc gtcttactca gtcgcgaggc cgcggtgggt ctggtccacc atgggcggga
     8341 ggcgtgtgct tcggcgcggc cggtggagac gatcgaggcc gtccgcgcgc tgccggtccg
     8401 gcacaactga tgtggtggga gaagcgtgag cgagaacctt cagcaggctc ggatggcgtc
     8461 cgtgatcgag ctcgcccagg aactgatccg gcggccgagc cgaggtggga tcgacaacta
     8521 tggaccggtc ctcggcgtgc tggaggactg gctcaacgac cgcgccgtac ctcaccgtcg
     8581 tttgtacggc gacgcaggtg agctggtggg gctgctcgtg gagatctcgg ggggtcggcc
     8641 gggccagtgg tggacactgg atgcctgcgt ggacaccgcc ccgtacggcg acgagaacgc
     8701 ctggtccttc ccgccggcca gcggggacgt ggtggacggc tggctgctcg gccgcggggc
     8761 ggccgactcc aagctcgccg tcgccatgtt ctgccacatc gccgacgacc tcatgccccg
     8821 cgccgctgac ctgaacggcg ggctagccat gctcctggac gtcgacgagc acaccggcgg
     8881 cttcggcggt gcccgcgcct acctcgccga cccgcgcgcg gcccgccctg ccggggtgat
     8941 gatcggctac cccgggctgg acgaggtcgt ggtcggcggc cggggcctgt ggcgggccac
     9001 cctcgcagtg cacgccccct ccgggcactc cggatccagc aagaccgtgg tcggtgcgat
     9061 cacccgggcc gcccacctcg tacggcttct cgacgaggcg gaactgcctg gtgtggacgg
     9121 ggcgtcgggg tttcccctgc cgccgaagct gtcggtgacc tccgtccacg gaggccaggg
     9181 cttctccgtc accccggacc ggtgcgagct gaacgtggac gtacgcacaa cccccggctt
     9241 cgacgcgcac gacgccgaga cgctggtccg caaggcggtc gccgagctcg acgcggagtt
     9301 gcctgcccct gcgtccaccg aggtcactcc ggtcgcggcc tggccgccgt tccgcctggc
     9361 cgaggacgag cagcccgccg ccgccctgct gggcgccgcc gccgagatgg gacttgcggt
     9421 caaggcgaag accgcagggc cgtcgaacat cggcaacctg ctggccggtg agggcatccc
     9481 ggccacggcc ggtttcgggg tgccgtacga ggggctgcac ggcatcgacg aacgtgccca
     9541 cctcgccgag ctgccccagg tctacgccgt ctaccagcgg gccgtcctca acctcctcaa
     9601 ggcgggctga cacctcccag gcgcatccca tatttctccc agatccactc ccagcaagtc
     9661 cccagctccg tctctgggaa cggatcttcg atcgcggtga catggagaca gcaccacttc
     9721 cacatccacc gatgacaagg gaggccggct atggccgagc agaccgtcac catcaagccc
     9781 gtcgaggaca agcccgcggc gacgccgcgc gtcaccttcg cgccgcagat cagcacccac
     9841 ccggtggcca ccctcaccct gggccgccag acgttcaacg actcggacaa ggacaactac
     9901 ttcgagggct gacacgtcct caccgagcac cccgggggcc ggccgcacga cagccggccc
     9961 ccgggcgcgt cacggagctg gtcgaagggg aggcaagcag atggaacagg agtggctgac
    10021 cggcggcaca gccgccgtcg atggagtagt aatcgaaggg ctgggcgacc tgcgccgggc
    10081 tcccggcaca cgggtacagg tggcctgcga ggggccggtt ggcctcgtgg tcgtgggcga
    10141 ctgccccgtc acccaggagg agctgagggc cgccctaccg gcgacgcggg tgggccagtg
    10201 ggccggactc acccggtggc ccggctcgta ctgggtggtc gccgacaacg ggcggcagcg
    10261 gttcgtgtgc ggcgacctgg ccggttcccg ggccgtctac tacacgctgc gcggcaacga
    10321 ggccgcgtgg gcaagccagg ctcggctgct ggagcaggac aggcggctca cgccggacct
    10381 gccgctggtg gcggccaggc tcaccgtggg cgagcaccac tggccccacc gcaccccgta
    10441 cgaacagatc cgcgtggtgc ccggcggctt cggactgctg ctcgcgccag aggcaccgcc
    10501 gcaactcgtc gatgtcaacg gtgtcgatcc cgtcgacgag ctccgcgaag gggccgtgcg
    10561 gttcgggcag gcgctcacca acgccgtcca gcaccgcgtc cgcgtcagcg gcggcgcggt
    10621 gggcgccgac ctgtcgggtg ggctggactc ctcggcggcc gtcgtactcg ctgccgacgc
    10681 cgggaccgtg cacgcggtga cctacaccga cggctacacc agcggggagg atatggcatt
    10741 cgcctcccgc atcgccgagc acaccggcgc ccggcacacg gtcgccaccg gaggcgacga
    10801 gcaactgccg ttcggcttcc ccgccggaca gccgtccgag gcggagccgg tgctggcggc
    10861 ggccatgtac gccatggacg ctgcctacct gcgccccgtg caggggctgc cgcttcacct
    10921 gaccgggcat ggcggggaca tcgtcctcga cgcctccagc tcctgctggg tccgcctcct
    10981 gcaggacggc caccgccgcg aggcccaccg acaggtggcg gcattcgccc ggctccgtaa
    11041 caccgcgccg ggcccgtact ggaaggccct caagcacgcc gctgacctcg gccgcagcgg
    11101 tgctctggag cgtgccgccg agaccctgga acacggtccg gtcacaccac agacgacggt
    11161 tgccggatgg tcgtggtgcc gtctgggggc cggagcgtcc tggctgaccg ctgacggccg
    11221 tcaccaggtc gccgcgctgc tgcggcaggc cgccggtgac cagcagccgg agctggcgga
    11281 cgagttcgac cagtgggccg ccctgcggtc ggtgggcacc tcggcccgcg gctgggcccc
    11341 atacggccac gcgctcggta tccggccggt gtacccgtac ctggacaacc aggttgtccg
    11401 ggccgcgttc ggcgtgccag ccctcgcccg gcggggtctg gtggcctaca agccgctgct
    11461 acgggccgcg ctgcccgagc tcccggactg gctgacctcc cgccggtcga aaggctcgtt
    11521 caccgcccag cgcatcgccg ggctggcccg gcaccgggat cggctcgacg aactgaccgc
    11581 ttccagtccg ctcgcggccg ctgggctgat cgaccccgca gccgtccgta cctcgctagc
    11641 tcagacggcc cgggggcaga gcgccacggt gatcgccgac ctgcaccagt tgatcgtgac
    11701 gtgctggtgg ctcagtggtc agacgaccag gagggaggtg gcagcgtgct gatccccgcc
    11761 ctccacgttc accacaacac ggggccggac ggcacggcgg tgatcgacgt gaagcgggag
    11821 acgtggctga tgctcgatca ggacgcttcc cggatctggc acgcgatcac cgtccgcggt
    11881 ggcaccgcca ggctcgccga tgagatcgcc gtccctaccg gccaggaccc acagcaggtc
    11941 agcggtcaga ttgtcgcgtt cgtcgacgat ctggtggctg ccggcgtgct cgtcgacacc
    12001 gaccggccgc ggcgagcacg gcgaaagcgg tggcgtcgat gacggtcatg gtccccaccg
    12061 cccggcccac cgctccatgg cgcgaccggt tggtggccgc cctcgcgctc gccctctccc
    12121 tggccgtgag tccgttgcca ctgcgctgga agctcgccgc cgtgcggctg ctgcgcggcc
    12181 tgccgtacgc acgcttggcc cggctcgaag ccctctacac cgcggttcag gcggtgattc
    12241 cctcgtggtg gccgggccgg atcgcgtgcg ccgagatcag tctcgctacc gtcatcgcga
    12301 ccgccctcac ctgccgccag gcccgctggg tacacggcgc ccgcttcatg cctcacgccg
    12361 cacacgcctg ggcggaggtc cccgagggcg cggtcggccg ggacatcggc gacgccgtcg
    12421 accggccctg gatgccagtc ctcgccgagc cgtagagagg ccctgggctg ccgtggtccg
    12481 gggctggccc gagcctcccc accccggacc acggattcac tcgatcgaat gaaagcgcac
    12541 ggggtggctg acggcagggg ccggtcgacc agcggcgacg cgggcctgcc ggaacaatcc
    12601 cgttgcccag cggcctcgtt cagctccctg atggggttcg tgagttcttc cgtatcctcg
    12661 ccgcccgtcg ccgccgcggg ccagccgccg gtcatgtgcc tggcctccga ccggcacttc
    12721 gaggcgagcg tcaacctgtc cacgtgggcc atagcacgcc gtctgcccca caccctcgcc
    12781 gaggcggccc ggctcggttg gcgcaccgac cgccgggccg tgctggccct gctgatctgc
    12841 cagatcggcg ccgccgccct caccgcgacc gcgctcgcag ccaccacccg cgtgctggct
    12901 accgtcttca ccggaggcga catcgccgcc ggcctgcgcg agaacctgac caccgtggtg
    12961 gtcctcaccc tcgcggcctc cggccgctac ctgctggacg ctgcagcccg cgcgtccgcc
    13021 gcccggctcg caccgaaggc cgtgcgcgag gccgaccttg aggtcatcac cacggcgacc
    13081 gccgccgagc tggtggcgta tgagaacccg gacttcgagg acgcccacgc cgccgcctcc
    13141 gacggcgcgg agaagaccgg cgacctcatc ctcgacgccc agctcctcac gtccgcggcg
    13201 gcacggatgg ccgccgcagc gacggtcgtc acccttctgc acccggtgat gctccccttg
    13261 ctggtcctct ccgtcgtccc ctgcgcgtgg ggcgccgtac gcggcgctcg gatcgagcac
    13321 gccgcccacc accgcaacct cgccgactcc cggctccgca acgtgttccg gtcgtacacc
    13381 actgagcgca acaccgccga cgaggtccgc gcgggcacca tggccgcctt cctcatccgg
    13441 cagtaccgcg tcgtctccgg ccgcctggag gccgagcagc tcaaggccac ccggcaggct
    13501 ctggtggtgc aggggatcgg tgacgcactc accgcggttg gcaccgctgc gacctggggc
    13561 gtgctcgtgc tcctggtagc gagtggccgg atggagcttg cggtcgcggg gaccgcagcc
    13621 ttggcggtaa ggacctctat ggcggctctt gcgacgacgg tgcgcgccgg ggcccggctg
    13681 ttccgcacct cgctgtccct ggacgactgg gcccgcttcc tggccgtggc caagccgtgg
    13741 acgacccgcc gcggctcggt cccgatcgcc gaggacgggc cgctggtgat cactgccatg
    13801 gacgtctcct tcacctaccc cggcgcccgc gcccccgcgc tcgacggcat caacctggac
    13861 ctcaagcgcg gtgaggtaat cgccctggtc ggcgagaacg gcgccggcaa gagcaccctc
    13921 gcccgcatcc tgaccggcct cttcctgccc accagcggtt cagtgcggtg ggacggagtg
    13981 gacctggcgg acgccgaccc ggccggggtg ctcgccaagg tggcgctcgt gccgcaggac
    14041 tacacccgct ggccgctggc cgcccgcgag aacatcaccc tcggccagcc ccgccccgac
    14101 ggcgacgccg ccgtgcgcgc cgccgctgag gcagccggcg ccgacaccgt catcgccgcg
    14161 ctgccccacg gactggatac ctcactggcc cgatcctggt ggggagggca tgacctgtcc
    14221 ggcgggcagt ggcagcgcgt cgcggtcgct cgcgccttcc atcgcgatgc ccccgtcctc
    14281 gtgatggacg agccgaccgc cgccctcgac gcccgtgccg agcaccggat ttacacccgg
    14341 ctcagggcac tcgccgaggg acgggcgacc gtgttcgtca cccatcggct ggccaacacc
    14401 cgcctcgccg accgcatcat cgtgctcaac cacggccgca tcgagcagat gggtgcgtac
    14461 gacgagctgg cacaccaagg gctgttccac gaactcctca aactccaaga agaccggtga
    14521 cccagtaatc cccgcgcaca atcgaattcc ggcgagcgcc aagggatccc gctggaatgc
    14581 cagcccgaac acacttcagc ccgtctcccg gaagggggcg ggctgaagtg ttgtgctgtg
    14641 tgggccctgc gcaacacgca ggacttgaca gagaagccgt cggccgtacc gaagttctcg
    14701 gtaccgagag tcacctgctt gacatcacca gcgttcagaa cgagcggtgc ggcgtagatc
    14761 ggctccattg cgttcatctc cctttgcggt attcacaact tcggcgcctt tcaccggagc
    14821 gctgccatgg agtcaacgcc tcaccagccc gcgcctgctc cccggatgcg gcagaggtgt
    14881 ttaacgtgtt tacagcccct tccttcaact ctcctgacag gccagattcg ttgggcacgg
    14941 cgtgagatcg cagaagacga tccgagaggg gtcacgatga ctgaacccaa tggacggtta
    15001 cgaaaagtca tcgccgagcc gggcatgccc caggaccgcc tgaccacctc tgcacagtgc
    15061 ccggccggca cagacggtgc ccggccgcgc atcgcccacc gctgacggct atcggccccc
    15121 ggggccgccg gggaagcggc ggacgtagcg tttttgccag ggggtctcga cggcgtggcg
    15181 gtcgtagtgg cggcggacga actccaccgc ccgcccgggc ggtacgccgt cgaggacggc
    15241 caggcaggcc agggccgtgc cggtccggcc gcggccgccg ccgcaggcga cctccacccg
    15301 ctcccccgcc gcccgctccc acacctcacg aagaacggtg cgggcgtcgg cggggtcggc
    15361 ggggagccgg aagtccggcc agcgcagcca tctggcctcc cagggaacct cggggggccg
    15421 tgtgccgagc aggtggacgg cgtaggcggg ggcggggccg tccggcaggg ggcggcgcag
    15481 gccgcggccg cggaccaggc ggccggaggg caggcgcagg acgccggggg tgtccgggtt
    15541 ccacaggccg ctcaccgggg ctccggtggg gtgaggtcga ggacgaggcc ggctcccagc
    15601 gcttcggccg gccgggacag gctccggacg gtgggtgagt ggcggcccgc ttccaggcgg
    15661 gagacgacgc tgtgcgtcac gccggcgagt ccggcctggg acaggccctg tcgcaggcgt
    15721 agtgcgcgga gcgggtctcc gggctcctgc ggggtcactg ccgcgtgtcc ttggcgctgt
    15781 cgtgccggtc gatcgagagc tcggtcacgc caccaccgta tatggcgtct ttgcgatacg
    15841 cggggcctgc ggggtgcccg caaggggggt gctcgcgggc acggcctgcg gccggggggc
    15901 gtggtggtcc cccggcccgg tgtgccggcg ggcggggccg ggggcggtca ggggttgttc
    15961 gggttgttca ggtaggtgag gacggccagg acgcggcggt tgccgctgtc gtcgtcggtg
    16021 atgccgagtt tcccgaacag ggaggtggtg tatttgctga tggcgctctc gctgaggtag
    16081 agccggcggc tgatggcctg gttggacagt ccttcggcca tcagggcgag gacggagtgc
    16141 tcgcgttcgg tgagctgtcc caggcgccgg tgggaggttc cgctggagag cagtccggcg
    16201 atgacggccg ggtccatggc ggtgccgccg gcggcgacgc gtgcgagggc gtcgatgaac
    16261 tggtcggcgt cgaagacgct ttccttgagg aagtagccga tgccgccggt gccgtcggcc
    16321 aggagttcgc gggcgtagag ctgttcgacg tactgggaga ggatcaggac gggcaggccg
    16381 gggagttcgg tgcgggcggc cagcgccgcg cgcaggccct cgtccgtccc ggtcgggggc
    16441 atccggacgt cgacgacggc gacgtccggc cgccatgtca gcagggcgtc gagggtctcg
    16501 gggccggtgg cggccgtggc caccacctgg tggccgtacg ccgcgatgag gcggaccatg
    16561 ccgtcccgca gcaggtagag gtcttcggct atgacgatgc gcatgggacc aaaattctca
    16621 cgtgggtcgg gccgcccgcc gggctggtga tctccaggtg gccgtcgaag accgcgaggc
    16681 ggcggcgcag ccccgccagc cctccgccgg ggcgctcggc ggcgccgccg tggccgtcgt
    16741 cctcgacctc gaccacgagg tgggtgccgt cgtgggcgag ggagatcctc gcccgggtgg
    16801 ccccggcgtg ccgggccgcg ttggtgagca gttcggcggt ggcgaagtac agggcggact
    16861 ccaccggcgc ctccaggcgc aagtgcccgc cggcggtgac ggtcgcttcc agggggctgt
    16921 ccagggcgag cgcgcgcacg gcgtccagca ggccccggtc gctgaggacc ggcgggttga
    16981 ttccccggac cagctcgcgc agttcggtca gcgaggtggc ggcgccggcc cgcgcgtcgc
    17041 gcatcagcgc cctggcccgg gcggggtcgc tctccatcag ccgctccgcg gtcgccagcg
    17101 agaggcccag gcccaccagg cgggcctggg ccccgtcgtg caggtcccgc tcgatccggc
    17161 ggatctcggc ggcctgcgcg agggtggcgt ccgcgcgctg ggccgtcagc tcctgcaccc
    17221 ggcccgccag caccatcgcc cgggaggggc gcaggaaacg ggcggccacc accggcagga
    17281 cccgccaggc gtagggggcg ccggcgaggg cggccgccag gcccagtgcc ccggcaaggc
    17341 gcgcggcggg cgccggccgg cccagccaca ggaccgccac cgcggccccg gcgggcggga
    17401 cggccgcggc cacgcccgcg gtgaacggga cgatcacggt gaaccgcaga tcgcgccagg
    17461 tggcgggatc acaccagcgc aggcgccact tctggtcacg cagggcatcg cggcgggtgc
    17521 gctcgtagga gaagccgttc caccactggc cggtggacat ccgcgtcacc ggccctgccc
    17581 gccggtaccc ggccggaagg acggtggccg tccaggtgcg cacgaggaag cggaccgccc
    17641 ggcagagggg gcgggacagg gcgagcgtgc ccgtgcacgc cagcaccagc ggcgccgtcc
    17701 acgaccacgg gttcgccgcc ccccaccgga tgcccagcgc cacggccccc gcccacacgg
    17761 ccgggaccag catgctcaac gccgccacgg cacacgcccg cacgaacccc gcaccggcgc
    17821 gccccgccca cgaacccagc tctctcatga cgcttccctc gcccccacat cttttttcct
    17881 tccggtgctc ccactgtgca ccggaaggaa ggggggcacg gccccggccc ggtcaggagt
    17941 ggggccagcc ccacctgccc gtacggccac accgataccg cccgcgtccg cgcggtccgt
    18001 agcgtcggcg ggcatggaaa ccgatacaca caccacggcc gggacgtccc tgcccggcga
    18061 ctcccgcgcc caggaagccc tcggcgcggc gaggaacagc atcaggctct acggcgggct
    18121 cggcgccctc gccctgctgg cggtcgtcgc ggtggcgggc agcgggtgtg cggtgaacac
    18181 gttcatgggg gtgcgggccg tcctgctgcc cgtggccgcc gtgctgctcc accggctggc
    18241 caccgccgcc tcccgcggct cccggcgggc ctacgagcgc gtgcgcgccc tcaccgtcat
    18301 cctgccggtc gccatcgtcg gcgtggacct gatcccgggc atctgcccgc cgtggtacgc
    18361 cgtgacgcag gccgtgtgca tggtgcccgt cgtgcgggcc gcggtcctcc tgcgcggccg
    18421 cgcgccgcgt gccgccttcg ccaaggggcg ctgagcgggc ggcgcacggg gacacccggt
    18481 gcccgccgtc ccgggggcgg ggcgccggct gcgccggggg tggcggcaaa gggggccgtc
    18541 gcgcacccat gcccctcgtg gagcgcaccc tgcgttccgt ccgacgcggt tgcaccggtc
    18601 ggtgattgcc cttgagggca ctcaccgatg gggcaggaag tccaaggcca cgtcgcactc
    18661 cagtgccgtc gcgaggcgct ggagaacagg aagggtcggg atggtttttc cggattcgac
    18721 gcgggagacg aacgcctgtc cggtcccggc gcgggcggcg agttccgctt gcgacatgcc
    18781 cagttgcacg cgccgcgccc gtacgagatc cgccgccatc aacctgaact ccggctgtag
    18841 cgcggcagct cggccgtgtc gatgacccag tcaccgaacg ggatcttgtc cccgaagacg
    18901 tacggggcac ggccctcgta gacgggagtc ccgcccttgt cgccgatggc ccagtagtgg
    18961 acgcacgtgc cgtcgcgggg atcgacgatg aggtagtgcg gaataccgag ctgcgggtag
    19021 tggcgcagct tgctgtcgta gtcgttctcc gggttggaga gggagacgat ctcgacggcc
    19081 gcgagaagag cgtgaggact gatggcgtca tcggtgtcca tggccgcctc ggggagaacg
    19141 agaacgtccg ggcggcgcag ctgcccgagg tcggcttcct cgatatcgcc ggaggtggtg
    19201 gccacgacgc cggcgggcag ctggggctga agctgacgct cgatgcgcaa ggccgcgaga
    19261 tcgtgacgac cggccgggct catcatcatg acgagctggc cgtcgctgat ctcgacatgg
    19321 gggctgaagg gcgcgggggg ggtgaagtgc tcgacgagag cacgcaggtg cctgtagatc
    19381 tcacgcttgg catcagccgt catgactcca ccctatatga cgaaatcgtc ataccccgag
    19441 tgtctctcct ccggcttcac ctggacggac tcatcacgag ctgggggtga tgaggaagac
    19501 ggggacgggg gcggcgccgg tgctgacgtt cagcaaggag gtgcgcgaga ggcggcagat
    19561 gcagcccggg gagtcggtgc cgaagaggaa ggggtcggtg ctctcggcgt actcccgcac
    19621 gcgcagccgg ccgccggcga ggtcggggta gggggcggtg ggcagcggta cccgttcctg
    19681 gaggacgtgc ggggtcagca gggcccggcc cagggcggag tgccaggcct ggtcggtggt
    19741 ctcccagccg cagagcacgc ctttgccgcc gtagtcgtcg ttgggtttga ggaccaggtg
    19801 cgcgcgccgg gcccgggcca ggtccaggag gccggtgcgg cgcccctcgg ggcaggtggt
    19861 gggccccgcc cgcacagccg ggtccagggc accaggtccc gggcggcggc cgcctcggaa
    19921 gggggcagca gcccgccggc ggccgggtcg gtgagcaggg ccaggaccga cttcttgtgc
    19981 gccaggtggc tggtgaaggg gttgaccatc acgcacgccc cggcggccca ggcgcgggtc
    20041 agcgggtgtg cggccagggc gtgcccgtag cgggcgaact cctccatcac cgcggtgccc
    20101 ttccaggcgt cggcgagcag gtcctgggtg acgaatgccg gcggggctgt gggcgttgca
    20161 ctcgacgaag gccgtccggc cgccggcgcg gaacccgtcg aggcgggagt gcgggctgag
    20221 cggcccggcc ggggggacca gggcggccag cgcggcctcc tggggggtga gggccaggtg
    20281 cgcgcggacg aggtcgcctt cttcgcccgg gtacagggcg tgggaggcca ggcggtcgag
    20341 ggcgagggtg gcgccttcgg cgcgtacgcg ggcgtggtcg gtggcgctga tgagccgggg
    20401 gcgcagcagg gggcgcaggg ggtggccgtg gaaggtcagg cccatggcgt gctggtgggt
    20461 gcgcaggtgg tggtcggtgg cccgggcggt gtcgtcctgg gtgaggaggg cgtggaagcg
    20521 gtggagggcg gtctccgtgt ctgtttccgg gtctgtttct gggtctgggg cgggcggggt
    20581 ggtcactgtg ggcggggccg gccggggtgg tccggctgcc cggtgggccc gtccggggcc
    20641 tggtcccggc ccgcgtgccg ggcccggttc cgctcctggt cctggtcctg ggcctggccc
    20701 tggttgtggt cttggtggtg gttgtggtct tggtggtggt gggggtcctc gccggggatc
    20761 tcctccaggt cctcgtccgg gccggcggtc aggaggtcgt gggcgccctg gacgacctgc
    20821 tgcggggtga agccgactcc gccggggacg gccgtacggg cctcctcgat cgcctctttg
    20881 acggacatgc ccagctggag gcggtcggcg gcttccttcg ccacgggata cagcgggccg
    20941 agggcttcgg cggcggggtg ggcggggtgc tcgtgcgggc ccatggtgtc gtccttgcca
    21001 cggtggatga ccgacggtga catgaaaaca caagggggcc gggggtgccc ggtgcccgca
    21061 cccctccccg gccccggcgc ctcttgccgg ggccggtccc ggggaggcgg cggggagtgc
    21121 ggggaggggt gtctggtgcg ccgtcacccg cccccggggg gttacaggtg ggtgggggcg
    21181 aacatcttca ggacggccgg gaggacgacg accgaggggc ccggggcggc gagggccttg
    21241 gccaggtcct cgcccaggcg gccgggggtg gtgcgggtgg cggggacgcc gaaggaggcg
    21301 gccagggcgg tgaagtcggg gcgggccagc tcggtggcgg tggcctggcc gaaggcgtcg
    21361 ctcatgtact cgcgcaggat gccgtagccg ccgtcgtcga cgatgagcca ggtgacgggc
    21421 aggccgtact ggcgggcggt ggcgagttcg gcgatcgagt acatcgcgcc gccgtcgccg
    21481 gagacggcca ggacggggcg ggcggggtcg gtggtggcgg cgccgagggc ggcggggaag
    21541 gcgtagccca ggccgccggc gccctgggcg gagtggaagg ggccggtgcg ggggtcgaag
    21601 gcggaccagg cccagtagcc caggatcgtc atgtcccaga agctgggggc gtcgtcgggc
    21661 agggcctcgc ggacggcggc caggacctgc tgctcggtgt ccaggtcctg gccggcgatg
    21721 cgggcgtgga ccttctccag cagggtgcgg gctcgttccc tcccctgccc ggcggggcgg
    21781 gaggtgacgg cgccggcgag ggcggccagg gcgggggcgg cgtcggcgtg cagggcgaga
    21841 gcctggtggt tggactccag cttgcccagg tccgcctcga tctggatcac ctgcccgcgg
    21901 gggcggaagg tgtggtagtt cgaggagagt tcgcccaggc cggagccggc gacgaggagg
    21961 acgtcggcgt cctggaggaa gccggtggtg tgccggtcct ccagccagga gcgcacggag
    22021 agcgggtgct gccaggggaa ggcgcccttg ccgccgaacg tgcaggccac cggcgcgtcc
    22081 agcttctccg ccagcgtgcg cagcgcccgc tgggcgccgg cgcggacgac gccgccgccg
    22141 gccaggacgg cggggcgggc ggcacggtcc agggcggcgg ccgcttcctc gatcagttcc
    22201 gggcgcggga ggagcggtgc gggggtggcg tccagggcgc gtacgggcgg cacggtggtg
    22261 gggtccagga ggacgtcctg cgggatctcc acccagaccg ggccggccgg tgcctggagg
    22321 gcgtggcgcc aggcggcggc cagggcggag gggatctggg aggcggtgcg gacggtgcag
    22381 gtgctcttga cgatgtcgcg gaaggaggcc tgctggtcgc gcagttcgtg caggtagccc
    22441 ttgcggccgc cgccg
//
