LOCUS       NZ_KZ195574            21239 bp    DNA     linear   CON 06-SEP-2024
DEFINITION  Streptomyces sp. CS113 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ195574
VERSION     NZ_KZ195574.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS113
  ORGANISM  Streptomyces sp. CS113
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8695358)
  AUTHORS   Malmierca,M.G., Gonzalez-Montes,L., Perez-Victoria,I., Sialer,C.,
            Brana,A.F., Garcia Salcedo,R., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Searching for Glycosylated Natural Products in Actinomycetes and
            Identification of Novel Macrolactams and Angucyclines
  JOURNAL   Front Microbiol 9, 39 (2018)
   PUBMED   29441046
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8695358)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Searching for glycosylated natural products in actinomycetes
            isolated from leaf-cutting ants: activation of two silent clusters
            and identification of a novel macrolactam
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8695358)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAY-2017) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 78.17x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002188365.1-RS_2024_09_06
            Annotation Date                   :: 09/06/2024 02:31:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,790
            CDSs (total)                      :: 7,719
            Genes (coding)                    :: 7,614
            CDSs (with protein)               :: 7,614
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 1 (5S, 16S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 105
            CDSs (without protein)            :: 105
            Pseudo Genes (ambiguous residues) :: 0 of 105
            Pseudo Genes (frameshifted)       :: 35 of 105
            Pseudo Genes (incomplete)         :: 81 of 105
            Pseudo Genes (internal stop)      :: 4 of 105
            Pseudo Genes (multiple problems)  :: 15 of 105
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:56:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3152186
            Orig. end                         :: 3173425
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ195574.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Salas's laboratory, A.
            Microbiology, University of Oviedo, Spain.
FEATURES             Location/Qualifiers
     region          1..21239
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="22"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21239
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21239
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11239](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11239)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            complement(331..771)
                     /locus_tag="B9W62_RS13545"
                     /old_locus_tag="B9W62_13580"
     CDS             complement(331..771)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973875.1"
                     /locus_tag="B9W62_RS13545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13580"
                     /product="ATP-binding protein"
                     /protein_id="WP_087807422.1"
                     /transl_table=11
                     /translation="MGSSAGEVIGVSDGEGDCAEWVFPAAPDAVRTARSLVRRTLGEWR
                     LDSIGDIAALLVSELVTNALRHATGPIGVRLVCDPAGAAGAAGVLRVEVSDPLPDPPRE
                     RVARPDDEDGRGLQLVASAARRWGTRPGEAGKTVWFELALPR"
     gene            complement(829..1242)
                     /locus_tag="B9W62_RS13550"
                     /old_locus_tag="B9W62_13585"
     CDS             complement(829..1242)
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010049087.1"
                     /locus_tag="B9W62_RS13550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13585"
                     /product="(deoxy)nucleoside triphosphate
                     pyrophosphohydrolase"
                     /protein_id="WP_087807423.1"
                     /transl_table=11
                     /translation="MTERIVVGAALVDGGRLLAARRSAPAELAGRWELPGGKVEPGETP
                     EAALVRELREELGVAAEPGERVPGQWPLRAPFVLQVWTARLRPGSAAPEPLEDHDELRW
                     LTPGQVWDVPWLDQDVPAVERVLAHLGREVGPR"
     gene            complement(1371..1562)
                     /locus_tag="B9W62_RS13555"
                     /old_locus_tag="B9W62_13590"
     CDS             complement(1371..1562)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973877.1"
                     /locus_tag="B9W62_RS13555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13590"
                     /product="SPOR domain-containing protein"
                     /protein_id="WP_087807424.1"
                     /transl_table=11
                     /translation="MNDSTVTLPWLVFRQDDNGNRYRVGRYATRAEAQQIADTLDGRGH
                     KQLYWVEKLGTAGTATTD"
     misc_feature    1623..1634
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 14.87"
                     /tool="antismash"
     misc_feature    1679..1692
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.65"
                     /tool="antismash"
     gene            complement(1968..2720)
                     /locus_tag="B9W62_RS13560"
                     /old_locus_tag="B9W62_13595"
     CDS             complement(1968..2720)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998196.1"
                     /locus_tag="B9W62_RS13560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13595"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_087807425.1"
                     /transl_table=11
                     /translation="MTFGEQPAYLRVAGDLRKKIADGLLPPHTRLPSQARIREEYGVSD
                     TVALEARKVLMAEGLVEGRSGSGTYVRERPVPRRVARSGYRPAGGATPFRQEQADGDGR
                     GTWESRSEQAEASGAVAERLGIKPGDRVMCTRYVFREAGEAVMLSTSWEPLDLTGRTPV
                     MLPEEGPLGGMGVVERMAAIDVVVDNVTEEVGARPGLAEELLALGGVPGHVVLVVHRTF
                     YASGRAVETADVVVPADRYRVAYHLPVR"
     misc_feature    complement(2733..2751)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.0"
                     /tool="antismash"
     gene            complement(2868..4001)
                     /locus_tag="B9W62_RS13565"
                     /old_locus_tag="B9W62_13600"
     CDS             complement(2868..4001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030057.1"
                     /locus_tag="B9W62_RS13565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13600"
                     /product="DUF4190 domain-containing protein"
                     /protein_id="WP_087807426.1"
                     /transl_table=11
                     /translation="MSIPPPPGPQGQYPQGPYAPQWGHPLAPYPRQAPVNGLAIAAFVL
                     GVLCFVPAVGLVLGLIALARIRKRGERGKGFAVAGCVLSSVGLALWTLTLATGAAADFW
                     DGFRDAARGEGTAYSLEKGQCFTTPGGSLQGVTYDVDEVPCTQEHDGEVFAAFDLPDGS
                     YPGDTEITRAADDRCYALQDAYAMDRWALPADVDVYYLTPTSASWRTGDREITCLFGNT
                     DERDTLTGSLRNDGARLDPDQHTYLLAEGHLNRAMDEVPAAEAVEEDLSGYRVWAGQVS
                     EALREEIAMLDGHDWPAGARRPVAELTEDLRSAQREWGLAAKATGLDAYFEHYSKGYDL
                     VVADSTVTARKALGLATTQPDYEGGSDGGGDDPGVEV"
     gene            complement(4168..4509)
                     /locus_tag="B9W62_RS13570"
                     /old_locus_tag="B9W62_13605"
     CDS             complement(4168..4509)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444324.1"
                     /locus_tag="B9W62_RS13570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13605"
                     /product="YrdB family protein"
                     /protein_id="WP_256976322.1"
                     /transl_table=11
                     /translation="MLASLKALNLLVMFLLELAVYAAVVLWGVAVGDARPVEVALGVGA
                     PVVMMTVWALFGSPRARYPARGGGRIVLEVLWFGAGGAALAASGRPRWAAVFAGVFLVN
                     AALRRLWRQ"
     gene            complement(4640..5470)
                     /locus_tag="B9W62_RS13575"
                     /old_locus_tag="B9W62_13610"
     CDS             complement(4640..5470)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (3-155). E-value: 1.9e-10. Score:
                     32.9. Matches aSDomain:
                     nrpspksdomains_B9W62_RS13575_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119688.1"
                     /locus_tag="B9W62_RS13575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13610"
                     /product="oxidoreductase"
                     /protein_id="WP_087807428.1"
                     /sec_met_domain="adh_short (E-value: 1.3e-30, bitscore:
                     105.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKVWLITGASSGFGRAIAEAALADGDVVVGAARRPEALDDLVAA
                     HPDQMEALRLDVADTAAAGDAVRDVLARHGRIDVLVNNAGRTHVGALEETGEDELRALF
                     DVHVFGPAALTRAVLPSMRERRSGAIVQMSSMGGQMSFAGFSAYSGTKFALEGMSEGLA
                     DEVRDFGIKVLIVEPGSFRTGLFEAGNAGISADGGAYPKVGETRGMIAAGDGSQPGDPA
                     KAAAVIRAALAAEHTPLHLPLGDDGVSAVLGHLGRVREEVEAWEKQTRATAFDD"
     aSDomain        complement(5006..5461)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9W62_RS13575_PKS_KR.1"
                     /evalue="1.90E-10"
                     /label="B9W62_RS13575_PKS_KR.1"
                     /locus_tag="B9W62_RS13575"
                     /protein_end="155"
                     /protein_start="3"
                     /score="32.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VWLITGASSGFGRAIAEAALADGDVVVGAARRPEALDDLVAAHPD
                     QMEALRLDVADTAAAGDAVRDVLARHGRIDVLVNNAGRTHVGALEETGEDELRALFDVH
                     VFGPAALTRAVLPSMRERRSGAIVQMSSMGGQMSFAGFSAYSGTKFAL"
     CDS_motif       complement(5411..5461)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9W62_RS13575_0001"
                     /evalue="1.20E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="B9W62_RS13575"
                     /protein_end="20"
                     /protein_start="3"
                     /score="11.6"
                     /tool="antismash"
                     /translation="VWLITGASSGFGRAIAE"
     gene            5564..6493
                     /locus_tag="B9W62_RS13580"
                     /old_locus_tag="B9W62_13615"
     CDS             5564..6493
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030054.1"
                     /locus_tag="B9W62_RS13580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13615"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_087807429.1"
                     /transl_table=11
                     /translation="MGMTTDVHVRELRYFAAVAEELHFTRAAERLYVSQPALSKQIRAL
                     ERQLGAELFRRDRQGVTLTEAGTALLPHARRVLADWTEGAAAVEAARAARRGTLVVGMS
                     TSPGRGGLLPAIRSRFTAAHPEAVLRLRQVTWEDPTAGLADGTADVAYVWLPLPDADRY
                     AWTVVAEEPRLVALPDTHPLAAREELDFADLADEPFLALPPEAGVLRDFWLALDERRAL
                     GGPDARPPRVGAEISGTEETYEALVAGLGICFVATGNAPLITLGGVVTRPVRGVAPSRY
                     ALARRREDEGRPLVRGYVEACRRVAGRA"
     gene            complement(6624..7196)
                     /locus_tag="B9W62_RS13585"
                     /old_locus_tag="B9W62_13620"
     CDS             complement(6624..7196)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030053.1"
                     /locus_tag="B9W62_RS13585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13620"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_087807430.1"
                     /transl_table=11
                     /translation="MDAGTDDVLDAVGPRLRALRRERGITLAHLSAATGVSESTLSRLE
                     SGQRRATLELLLPLARIYDVPLDDLVGAPRTGDPRIHLKPIKRYGMVFVPLSRRPGGTQ
                     AFKMIIPSRPAPLEPTPQTHEGFEWLYVLGGRLRLLVGERDLTLSPGEAAEFDTSLPHW
                     LGSADGGAVELLVLFGLQGVRAHVRSG"
     gene            7373..7999
                     /locus_tag="B9W62_RS13590"
                     /old_locus_tag="B9W62_13625"
     CDS             7373..7999
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /GO_function="GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (41-138). E-value: 5.2e-08. Score:
                     23.2. Matches aSDomain: nrpspksdomains_B9W62_RS13590_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006131412.1"
                     /locus_tag="B9W62_RS13590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13625"
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="WP_087807431.1"
                     /transl_table=11
                     /translation="MSATDAVTFWDGVYAARPAPDAPRPNVRLVETVTGLPPGDALDLG
                     CGSGGDALWLARRGWRVTAVDISGVAAERLAGHARAHALGDLVDAVRHDLRASFPEGRF
                     DLVCAHYLHTPFDLDRASVLRTAAHALRPGGRLLVVDHGSTAPWSWDQDPDARFPSPEE
                     VAADLALDPGTWRVERADAPRRTATGPGGRTAEVVDHVLLVRRAG"
     aSDomain        7496..7786
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9W62_RS13590_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="5.20E-08"
                     /label="B9W62_RS13590_oMT.1"
                     /locus_tag="B9W62_RS13590"
                     /protein_end="138"
                     /protein_start="41"
                     /score="23.2"
                     /tool="antismash"
                     /translation="LDLGCGSGGDALWLARRGWRVTAVDISGVAAERLAGHARAHALGD
                     LVDAVRHDLRASFPEGRFDLVCAHYLHTPFDLDRASVLRTAAHALRPGGRLL"
     gene            8124..8621
                     /locus_tag="B9W62_RS13595"
                     /old_locus_tag="B9W62_13630"
     CDS             8124..8621
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030051.1"
                     /locus_tag="B9W62_RS13595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13630"
                     /product="DinB family protein"
                     /protein_id="WP_087807432.1"
                     /transl_table=11
                     /translation="MSTTPRTHRRDTPPPRTGGSEAETLRGFLDYLRTSIAGKVEGAPE
                     PRVRTAAVPSGTNLLGLLHHLTHVERALFLGEEVRSWPATFRAAPEDGVAEVLARYRAA
                     VERANRVLDACADLGAPLPRARPGRPAPSVRWALTHMIEETGRHAGHADILRELIDGTT
                     GR"
     gene            complement(8655..10004)
                     /locus_tag="B9W62_RS13600"
                     /old_locus_tag="B9W62_13635"
     CDS             complement(8655..10004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006132034.1"
                     /locus_tag="B9W62_RS13600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13635"
                     /product="hypothetical protein"
                     /protein_id="WP_373433683.1"
                     /transl_table=11
                     /translation="MTDTAGPAADTSEADTSDTASEADAAADAAAVGTDADGPPPIAPT
                     TRVLLHDLAVRRDRDEWIVGRMTTRTFVALPAAGARAVELLGAGLSVRRTEESLRAETG
                     EEFDIADFVGDLAALGFVARIGDHPVPDAEPPRASLPWLRPRHVRLALHPVLPLLVGAL
                     LVAAVVVLVRRPDLLPGYRDLLWSRHGSVVLLSGAAAGWTLLLAHELAHLVTARAAGVP
                     GKMRLGTRLQFLVMQTDISGIELAPRRHRLTAYLAGIALNLSVASSLVLTLALTETGTT
                     AHRLLAAALLLALLPLPFQCMVFTRTDLYFVLQDLTGCRDLYGDGLAYARYRARRSVRA
                     VRSVRRGVRAGGRDDDPSARLPAHERRAVRVYSVVLVVGTAACLAFMAAVTLPVDLALL
                     VRAVRGLGPGHGLAGNADAVTVLVVLGGVNVLWLVTWWRNRRSRRSAGAT"
     gene            complement(10001..11239)
                     /locus_tag="B9W62_RS13605"
                     /old_locus_tag="B9W62_13640"
     CDS             complement(10001..11239)
                     /GO_function="GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387620.1"
                     /locus_tag="B9W62_RS13605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13640"
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_087807433.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 4.2e-27,
                     bitscore: 93.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 4.7e-36, bitscore: 123.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVHAMRRPRIKPEHRAYRTVDGHVRIGSVVHGIGAEVKDPDGWV
                     WTLVRAMDGTREAADVVAEVSGRHPELRLPAPDIVQAMADLTDAGYVEDAGAPPPPELS
                     ERDRERHSRGMTLLRWMDLRPRSSAWEPQVLLRRARVLLVGAGGTGSAAARDLVASGVG
                     RLHCVEPDVVELSNLNRQTLFGERDLGRPKIDAVLAGLRALNADAEVTGERREVRGPAD
                     LEDLLTGAGGANGSGDADGADGPDGSPGYDALLLAADRPATIRRWANQVCLASGTPWAE
                     AGYRGPLVSVGVFTPGRGACWQCLRDAEIERRDLRLAPGQDEDVASPRMPWNPANAVTA
                     GLSGGLLAHAALMLLCGVPPVEPGCRFGLNLMVPGDPVLQRSPRRPDCPACRPVEPDPA
                     PAARPGSGDRGPS"
     aSDomain        complement(10934..11224)
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_B9W62_RS13605_Pantocin_Microcin_RRE.1
                     "
                     /evalue="1.50E-29"
                     /identifier="RREFam017.1"
                     /label="B9W62_RS13605"
                     /locus_tag="B9W62_RS13605"
                     /protein_end="102"
                     /protein_start="5"
                     /score="93.0"
                     /tool="antismash"
                     /translation="MRRPRIKPEHRAYRTVDGHVRIGSVVHGIGAEVKDPDGWVWTLVR
                     AMDGTREAADVVAEVSGRHPELRLPAPDIVQAMADLTDAGYVEDAGAPPPPE"
     misc_feature    11253..11265
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.22"
                     /tool="antismash"
     gene            11525..12829
                     /locus_tag="B9W62_RS13610"
                     /old_locus_tag="B9W62_13645"
     CDS             11525..12829
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387607.1"
                     /locus_tag="B9W62_RS13610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13645"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_087807434.1"
                     /transl_table=11
                     /translation="MHRYLTVAEVTESARRLVSRFPGSCRLRRIGTSRAGRPILMLSVG
                     HGPRHVLVVARPHSDEPVGGATALALAERVADGDRRSTATDPDTVTWDIVLCLDPDGAA
                     LSEGLEAATAGPGHTLDRYYRTAFRPVAAEQPEWAPIEGWRLPESRALFDAIDELRPVL
                     QCSLHSVDAGGTWVQLTRGLPGLAAPFRASATSVGVPVQHGTYDALYWENPAPGIHVLP
                     PPDSTARLAAGSENIGLSTWCAPRRYGGVTAIVEVPLWATGTADDLSPHPDPAGALREL
                     SGLVREGGRQVTAVFEKARGFLPPAGDSPPRRVLEWMADGLYDLVAASWEPLLRQPDED
                     PRTTTSPRLTTAGISALEVVARRQPLRAAGLLLRLLREADDPAAAGLRHELDELFTTWC
                     TEFEQSLRLRWVPVADQVALQTGTVVAAAECALRR"
     gene            complement(12965..13921)
                     /locus_tag="B9W62_RS13615"
                     /old_locus_tag="B9W62_13650"
     CDS             complement(12965..13921)
                     /NRPS_PKS="Domain: PKS_ER (14-313). E-value: 9.3e-40.
                     Score: 128.6. Matches aSDomain:
                     nrpspksdomains_B9W62_RS13615_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973909.1"
                     /locus_tag="B9W62_RS13615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13650"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_087807435.1"
                     /sec_met_domain="ADH_N (E-value: 4.2e-06, bitscore: 25.4,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.5e-09, bitscore:
                     36.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVQFDRFGPPDVLRVDDIPAPRPGPGEVLVDVHAASVDAGETA
                     FRAGRMRRVTRARFPRGLGSDFAGRVAAVGSGVRAWAVGDAVWGLMPHLTFGAIADHVA
                     VPEQRLARAPENLSPVEAAALPVVGTTAMTALIGKARLQPGERLLVRGATGGVGSIAVQ
                     LGKALGAHVTALAGARNLDWITRLGADEAVDYRTTRPGDLDRFDVIVDVVGTDLGAYQA
                     RLARGGRLVALSFDSDRVVSSMLGIALRAAAAPRRVKMFSNNPSADRIADLTRAVEAGT
                     IRPVVDTVFPVGDIAAVHRRLESGGVRGKYVIDMRLP"
     aSDomain        complement(12983..13879)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9W62_RS13615_PKS_ER.1"
                     /evalue="9.30E-40"
                     /label="B9W62_RS13615_PKS_ER.1"
                     /locus_tag="B9W62_RS13615"
                     /protein_end="313"
                     /protein_start="14"
                     /score="128.6"
                     /tool="antismash"
                     /translation="LRVDDIPAPRPGPGEVLVDVHAASVDAGETAFRAGRMRRVTRARF
                     PRGLGSDFAGRVAAVGSGVRAWAVGDAVWGLMPHLTFGAIADHVAVPEQRLARAPENLS
                     PVEAAALPVVGTTAMTALIGKARLQPGERLLVRGATGGVGSIAVQLGKALGAHVTALAG
                     ARNLDWITRLGADEAVDYRTTRPGDLDRFDVIVDVVGTDLGAYQARLARGGRLVALSFD
                     SDRVVSSMLGIALRAAAAPRRVKMFSNNPSADRIADLTRAVEAGTIRPVVDTVFPVGDI
                     AAVHRRLESGGVRGKYVI"
     CDS_motif       complement(13430..13489)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9W62_RS13615_0001"
                     /evalue="2.60E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="B9W62_RS13615"
                     /protein_end="164"
                     /protein_start="144"
                     /score="16.8"
                     /tool="antismash"
                     /translation="GERLLVRGATGGVGSIAVQL"
     misc_feature    complement(13965..13979)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.13"
                     /tool="antismash"
     gene            14076..14684
                     /locus_tag="B9W62_RS13620"
                     /old_locus_tag="B9W62_13655"
     CDS             14076..14684
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387606.1"
                     /locus_tag="B9W62_RS13620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13655"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_087807436.1"
                     /transl_table=11
                     /translation="MTRENPGPPKRADARRNYDRILEAAAAEVARRGADASLEEIARRA
                     GVGSATLHRHFPSRWDLLQAVFQERVAQLCGEARSLAGEHPPATALTTWLTSLAVFGAV
                     TRGAARALLRATGTTASTASTAPDSHCEQLLMDAGGDLLARAQHAGTVRDDVTVVELVS
                     LANAVSLAAEHTPDAARHATRLMEIAVEGLGVSGHRAPE"
     gene            complement(14692..16182)
                     /locus_tag="B9W62_RS13625"
                     /old_locus_tag="B9W62_13660"
     CDS             complement(14692..16182)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973911.1"
                     /locus_tag="B9W62_RS13625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13660"
                     /product="carboxylesterase/lipase family protein"
                     /protein_id="WP_087807437.1"
                     /transl_table=11
                     /translation="MNQHSGPVVTTAQGAVRGLRRDGTLTFLNIPYAAPPRGAGRFAPP
                     RPHEPWDGVLDATAPGPSAPQSARRLGDIDMTPYFGPGWSRGEDYLTVNVFAPAAGGDA
                     LPVMVFVHGGGFVAGSTRAALYDGSAFARDGVVLVTLNYRLGIAGFLDVPGAPANRGLL
                     DVVAALRWVRENVSAFGGDPRNVTLFGQSAGATIVGGVLATPEAAGLFRRAIVQSGSGR
                     GAFTPEQAARVTRAAAGALGIEPHVDAFGAIPDERLVEAAGQLTGIDLRTGTHGDPLIG
                     LSPFSLVLDTQPAASVAAGLAADVDLLVGTNAEEGNLYLVPVGTYATSTAADVDEAAAR
                     SHPDPERLVETYRAARPGASFAELRSAIMADALFGAGSRALADAHAAHPRSATYAYRFA
                     WRSHALDGELGATHGVELPFVFDLADRPELHGPDALLGPDEAPADLAGRVHDTWVRFAR
                     TGDPGWDPYDTDRRATMCIDAEWTQADDPRGRERRVWS"
     gene            complement(16197..17117)
                     /locus_tag="B9W62_RS13630"
                     /old_locus_tag="B9W62_13665"
     CDS             complement(16197..17117)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387617.1"
                     /locus_tag="B9W62_RS13630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13665"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_087807438.1"
                     /transl_table=11
                     /translation="MDTITLGDVTVTRVREYYGPVDLTPEAFVPDSPAQAWDTHRSWLV
                     PDFLDAETRIVNTAIQTWVLRSEGRTILVDTGVGNHKDRPYAPVWSRLDTDFLGNLARA
                     GVRPEDVDIVINTHLHVDHVGWNTYLDGRTWVPTFPNATYLMAKADFDYWNPANEIKTL
                     LGRGNQNVFEDSVAPVHEAGLALLWEGSHRIDSHLRLDLAPGHTPGSSVLRLESGSDRA
                     LFVGDLMHSPIQIHEPDANSCFCEDPAEARATRHKLLGAAVDSNALVFPAHLGGHGAAE
                     VVRSGSKFAIKGWAPFAKYTETEQA"
     misc_feature    complement(17417..17433)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.35"
                     /tool="antismash"
     gene            17437..20238
                     /locus_tag="B9W62_RS13635"
                     /old_locus_tag="B9W62_13670"
     CDS             17437..20238
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030031.1"
                     /locus_tag="B9W62_RS13635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_13670"
                     /product="AAA family ATPase"
                     /protein_id="WP_256976323.1"
                     /transl_table=11
                     /translation="MANGGSARAGRSPAADPGPTVLGRETETADLMRRVADGRSRSAVL
                     VVEGEPGVGKSALLDLAVRRTRGAGHRVLRAVGSESEQHLAFAGLHQLLRPVLGDLDAL
                     PARQRSSLGAALGLADPAAPPEALLVGLAVLTLVSDLAEPAPLLVVVDDAQWIDRASLD
                     VLSFVARRMDSEPVTLLMGVRAAAVLPGFDKGYERLVIGPLSADAANRLLDEQPGRPTG
                     RTRARILQEAAGNPLALVELARAAASGQPEGAGREGPLPVTDRLEGVFARHLRHLPDTT
                     RRALLLLAATDAADAPAAARGLPEAADTVWAPAERAGLVRRDSRGVSFRHPLVRSAVYH
                     AAPFEERRSAHLALAGLLGEEPDRRAWHLAAATVRPDAQVAAALLETAGRARRRGGHAA
                     AAAALERAAHLSPRRADQARLLADAAGAAVLTGQLGWVEHLAAEVGKRTDDPALISRAA
                     LATGQLMTVGAHHTAAFALLSRIAGEAADASSPHLLDALAAAAVVRYYSGEESQRQRIE
                     ALLSQVPDSPAGGALRAWTLAVSDPTGAGASLAPALPRLIAAAGDDAGSLMALAVVAWI
                     LDRTTLAARTFDEAFGRWQALGPLPAGLACAAGWTYLEQGRWAEARSVAAEITEVASQA
                     GLVHAEACARALDATVLALLGDPAEARRNAERALALVDPLESRSVAVFARRALGLAAVA
                     EGDYDTAYAQFRAAFTEDGDPVHYHVSPTVLAELAAAAVRGGRREPAAVLLERSARRTG
                     TSPSVRASSLVERGRALLAEPEHAERHFRAALADEAGEQWPFERAQTRLDYGEWLRRRR
                     RIAEARPLLTGALDTFRRLGARPWIERAKAELRAAGIEADSAAPGALTELTPQQQQIVR
                     LAARGLTNREIGEKLFLSPRTVGSHLYRAFPKLGITARAQLRDTVDDALADAGSAHWRG
                     FHP"
     misc_feature    complement(21217..21235)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.31"
                     /tool="antismash"
ORIGIN
        1 ctccttggcc ctcgctggta tctcgctcac gcgaaccgtc ccctccagct caccgcatcc
       61 ggcaccggtc accggaggcg gctgcccgca gtatccagca ctacggcgcc gcacgacacg
      121 gtgttcacga tcacagcacg gtcccgatgg ttttcggtcc ggaccgcgac aacacttcca
      181 gtcttctaac cagcggacac ggcatcgaat cacgcagttc cacaactgcc actggcctga
      241 accggttgac ggccggggcc agggacgatg tcgggacatt acggacgttc gaccggcgcg
      301 acggcgacgg tgcgtcacgg gactgtcgcg ctagcgcggc agggcgagtt cgaaccacac
      361 ggtcttcccc gcctcaccgg ggcgggtccc ccagcggcgc gcggcggacg ccaccaattg
      421 cagaccccgg ccgtcctcgt cgtcggggcg ggcgacgcgc tcgcggggcg ggtcgggcag
      481 cgggtcggag acctccaccc gcagaacccc ggcagccccg gcggctccgg cggggtcgca
      541 caccaggcgg acaccgatgg ggccggtggc gtgccgcagc gcgttggtga ccagctcgct
      601 caccagcagg gcggcgatgt ccccgatgct gtcgagccgc cactcgccca gcgtgcggcg
      661 gaccagggag cgggcggtgc gcacggcgtc cggcgccgcg gggaagaccc actcggcaca
      721 gtcgccctcg ccgtcactca cgccgatcac ttccccggcc gacgacccca ccctgtccgt
      781 tttcatgggg ttaatgggca catacccttt atccgggcgc ggtaccgctc accggggccc
      841 gacctcgcgc ccgaggtggg cgagcacccg ctcgacggcc ggtacgtcct ggtcgagcca
      901 gggcacgtcc cagacctggc cgggggtcag ccagcgcagt tcgtcgtggt cctcaagggg
      961 ttcgggggcg gcggagccgg ggcgcaggcg ggcggtccac acctggagga cgaacggcgc
     1021 cctcaggggc cactgccccg ggacgcgctc accgggctcg gccgccaccc cgagttcctc
     1081 gcgcagttcg cgcacgagtg ccgcctcggg cgtctcgccc ggctcgacct tgccgccggg
     1141 cagctcccac cgtccggcca gttcggcggg tgcgctgcgg cgcgcggcga gcaggcgccc
     1201 gccgtcgacg agggcggcgc ccaccacgat ccgttccgtc atgcgccgga gcctacggcc
     1261 tgcccggccc gccgccgtgg gtcggtccgc ggcaggtcgg tccacggtgg gtcggtccgg
     1321 ggtcggccgg accagggtcg gccggtccgc ggtgatcggt ccacggtggg tcagtccgtc
     1381 gtggccgttc cggccgtgcc gagcttctcg acccagtaga gctgcttgtg cccgcgaccg
     1441 tcgagggtgt ccgcgatctg ctgggcctcc gcccgggtcg cgtacctgcc cacgcggtag
     1501 cgattgccgt tgtcgtcctg ccggaagacc agccagggaa gagtgaccgt gctgtcgttc
     1561 atcgcgcccc tccgcttccc gttcccgccg cccgcggcac ccgccgcgcc ccgcccgcca
     1621 aggaaaccgc aatccgcata tgcccgagcc tacgcccaac cttcacggag cgaatacggc
     1681 tttacacaaa gaggtacgca accagccaga acgcaggggg cgcacgatgc ggaacgcgcc
     1741 gtctgcgcac cccgacacct ccggtcgcgg gcatgacggg accgggcgag gcgacctggg
     1801 gaaacggccg gatcgcggcg ccggcgcgtg cggcgccgcg ggcccgtgag gccgtgcggg
     1861 ggccgggctg gagcgcggga ggcgcacgac aggcgtgcgc catctcacac cggctcaggt
     1921 cgcggccggg cggttgaact cccccggccg tggcgctggt tgacggacta ccggaccggc
     1981 aggtggtacg ccacccggta acggtcggcc gggacgacca cgtcggcggt ctccaccgcg
     2041 cgcccggagg cgtagaacgt gcggtggacg accagcacca catgccccgg tacgccgccc
     2101 agggcgagca actcctcggc gaggccggga cgggcgccga cctcctcggt gacgttgtcc
     2161 acgacgacgt cgatggcggc catgcgctcg acgacgccca tgccgccgag cggcccctcc
     2221 tcgggcagca tcaccggggt gcggccggtc aggtccaggg gctcccacga ggtggagagc
     2281 atcacggcct caccggcctc ccggaagacg taccgcgtgc acatcacccg gtcgccgggc
     2341 ttgatcccca gccgctcggc gacggccccg ctcgcctcgg cctgctcgct gcgcgactcc
     2401 caggtgccgc gcccgtcgcc gtcggcctgc tcctggcgga agggcgtggc gccgcccgcc
     2461 ggccggtacc cggagcgggc gacgcggcgc gggacgggcc gctcgcgcac ataggtgccg
     2521 gaaccggagc ggccctcgac cagcccctcg gccatcagca ccttgcgggc ctccagcgcg
     2581 acggtgtccg agacgccgta ctcctcgcgg atccgcgcct gggacgggag gcgggtatgg
     2641 ggcggcagca ggccgtcggc gatcttcttg cggagatcac ccgcgacacg cagatacgcc
     2701 ggctgctcac cgaatgtcac tggccgctcc catcaggttg tacagacagc aacagcgtgg
     2761 caaccgtagg ttggctcagg caagcaaagg ccaaagaatc actcgatgtg atgacttgtg
     2821 cggcccgagg gctttacgca ggcactttct ccccactgag gccgctctca cacctccacg
     2881 ccggggtcgt ctcccccgcc gtcgctcccg ccctcgtagt ccggctgcgt ggtggcaagg
     2941 cccagagcct tgcgggcggt gaccgtgctg tcggccacga cgaggtcgta gcccttgctg
     3001 tagtgctcga agtacgcgtc gagaccggtg gccttcgccg ccaggcccca ctcccgctgt
     3061 gccgaccgca ggtcctcggt caactcggcg accggacgcc gggcaccggc gggccagtcg
     3121 tgcccgtcca gcatcgcgat ctcctccctg agcgcctccg agacctgccc cgcccagacc
     3181 cggtagcccg agagatcctc ctcgacggcc tccgccgcgg gcacctcgtc catggcccgg
     3241 ttcaggtggc cctccgcgag gaggtacgtg tgctggtccg ggtcgagccg cgcgccgtcg
     3301 ttgcgcagcg agccggtcag cgtgtcccgc tcgtccgtgt tcccgaacag gcaggtgatc
     3361 tcgcggtcac cggtccgcca gctcgcggag gtcggggtca ggtagtacac gtcgacgtcg
     3421 gccggcagcg cccagcggtc catcgcgtag gcgtcctgga gggcgtagca ccggtcgtcg
     3481 gcggcgcgcg tgatctccgt gtcgcccggg taggacccgt ccggcaggtc gaaggcggcg
     3541 aacacctcgc cgtcgtgctc ctgtgtgcag ggcacctcgt cgacgtcgta cgtcaccccc
     3601 tggagggagc ctcccggggt ggtgaagcac tggcccttct ccagggagta ggcggtgccc
     3661 tcgccgcgcg cggcgtcccg gaagccgtcc cagaagtcgg cggcggcgcc ggtggcgagc
     3721 gtcagcgtcc acagggccag ccccacggag gacagcacgc acccggccac cgcgaacccc
     3781 ttgccccgct cgccgcgctt gcggatccgg gccagcgcga tcaggccgag cacgagcccg
     3841 accgccggca cgaagcacag cacgccgagc acgaacgcgg cgatggcgag cccgttcacg
     3901 ggagcctgcc gggggtacgg cgcgagcggg tggccccact gcggagcgta cgggccctgg
     3961 gggtactgcc cctggggtcc cggcggtggc ggtatcgaca cgggaaccgt gctcctgttc
     4021 gagaggctgg tgcggcgacg ggtgcggcct cgcgcatcgt aagggggcgc gcacagggag
     4081 cgctgcgcgg ggcgcgccgc gcgaggagcg ggcgcgcggg gcgcggggcg cggggcgcgg
     4141 gtgcgccggg aacgggtgcg ccgggcgtca ctgcctccac agccgtctga gcgccgcgtt
     4201 gaccaggaag acgccggcga agaccgctgc ccagcgcggt ctgccggagg cggccagggc
     4261 ggcgccaccg gcgccgaacc acagcacttc caggacgatc cgtccgcctc cgcgcgccgg
     4321 gtaccgggcg cgcggcgatc cgaacagcgc ccacaccgtc atcatcacga ccggcgcgcc
     4381 cacgccgagg gccacctcga ccggccgggc gtcgccgacg gcgacccccc agagcacgac
     4441 cgcggcgtac accgcgagtt ccagcaggaa catcaccagc aggttgaggg ccttcaagga
     4501 cgcgagcacg agggactcct ggttcggcac ggatcggtcg gcacggatcg gtcggcacgg
     4561 acacggtcgg gcggggagtc cgggcaccgg cctccccgcc gtgtaccgaa ccatgccggg
     4621 gattccgtcg cgccggggct cagtcgtcga acgcggtggc ccgggtctgc ttctcccagg
     4681 cctcgacctc ctcgcgtacc cggccgaggt ggccgaggac cgcgctgacg ccgtcgtccc
     4741 ccagcggcag gtgcaacggg gtgtgctcgg ccgcgagggc cgcgcggatg accgccgccg
     4801 ccttggcggg gtcgccgggc tggctgccgt cgcccgcggc gatcatcccg cgggtctcgc
     4861 cgaccttggg gtacgcgccg ccgtccgcgc tgatcccggc gttcccggcc tcgaacagac
     4921 ccgtgcggaa ggaacccggc tcgacgatca gcactttgat cccgaagtcc cggacctcgt
     4981 ccgcgagccc ctcggacatg ccctccaggg cgaacttggt gccgctgtac gccgagaagc
     5041 ccgcgaagga catctgcccg cccatgctgc tcatctgcac gatcgctccc gagcggcgct
     5101 cccgcatgga cggcagcacc gcgcgcgtca gcgcggccgg tccgaagacg tgcacgtcga
     5161 agagcgcgcg cagctcgtcc tcgccggtct cctccagggc gcccacgtgc gtgcggcccg
     5221 cgttgttgac gagcacgtcg atccgtccgt gccgcgccag cacgtcccgt acggcgtccc
     5281 cggcggcggc cgtgtcggcg acgtccaggc gcagcgcctc catctggtcc gggtgcgcgg
     5341 ccacgaggtc gtcgagcgcc tcgggacgcc gtgccgcgcc gaccacgacg tcgccgtcgg
     5401 ccagggccgc ctcggcgatc gcccgcccga agccgctgct cgcaccggtg atcagccaca
     5461 ccttgttcat tccgactccc tggtcccctc ggttcccctg ctccgacgcc aaccaccctg
     5521 ggccacacgg cggttgccgg tccaagaccc gcggtgataa cccatgggca tgacgacgga
     5581 cgtccacgtg cgggagctgc gctacttcgc ggcggtggcc gaggagctgc acttcacgcg
     5641 ggcggccgag cgcctgtacg tgtcgcagcc cgcgttgagc aagcagatcc gggcgctgga
     5701 gcggcagttg ggcgccgagc tgttccgccg tgaccgccag ggtgtgaccc tcaccgaggc
     5761 gggcacggct ctgctgccgc acgcccggcg cgtgctggcc gactggaccg agggcgcggc
     5821 ggcggtggag gcggcgcgtg cggctcggcg cggcaccctc gtcgtcggca tgagcaccag
     5881 ccccggtcgc ggcggtctgc tgccggcgat ccgctcccgc ttcacggcgg cccacccgga
     5941 ggcggtcctg cggctgcggc aggtgacctg ggaggacccg accgcgggcc tggccgacgg
     6001 caccgccgac gtcgcgtacg tgtggctgcc gctgcccgac gccgaccgct acgcctggac
     6061 ggtggtcgcc gaggagcccc gcctggtcgc cctgcccgac acccaccccc tcgccgcccg
     6121 cgaggaactc gacttcgcgg acctggccga cgagccgttc ctcgccctgc ccccggaggc
     6181 gggcgtgctg cgcgacttct ggctggcgct ggacgaacgg cgcgcactgg gcggaccgga
     6241 cgcccggccg ccgcgcgtcg gcgccgagat ctccggcacg gaggagacgt acgaggccct
     6301 ggtcgcgggt ctcggcatct gcttcgtggc cacgggcaac gccccgctga tcactctggg
     6361 cggcgtcgtc acccgcccgg tccgcggcgt ggcccccagc cgctacgctc tggcccggcg
     6421 ccgcgaggac gaggggcggc cgctggtgcg cgggtacgtg gaggcgtgcc gccgggtggc
     6481 gggccgggct tgaccgcccc tcaggacggc cgcgcggacc gttcgtcggg ggcctctcga
     6541 agccgtgtcc cacgggacgg ccgtctcccg ctcagctcgt cccctcgcgc acggcgtccc
     6601 ctcccggccc ggtccaacgg ccctcagccg ctgcgcacat gggcccgcac gccctgaaga
     6661 ccgaacagca cgagcagttc caccgcgccg ccgtcggcgc tgcccagcca gtgcggaagg
     6721 gaggtgtcga actcggccgc ctcgccgggc gacagcgtca ggtcgcgctc gccgaccagc
     6781 aaccgcagac ggccgccgag cacgtacagc cactcgaagc cctcgtgggt ctgcggggtc
     6841 ggttcgagcg gcgcgggacg gctcgggatg atcatcttga acgcctgggt gccgcccggc
     6901 cgccgggaca acggcacgaa gaccatgccg tagcgcttga tcggcttcag gtggatacgg
     6961 gggtcgcccg tgcgcggggc gccgacgagg tcgtccagcg ggacgtcgta gatccgggcg
     7021 agcggcagca gcagttccag ggtggcgcgg cgctgcccgc tctccagccg ggacagcgtg
     7081 ctctccgaca cgccggtcgc cgccgagagg tgggcgaggg tgatgccccg ctcgcggcgc
     7141 agcgcgcgca ggcgtgggcc caccgcgtcg agtacgtcgt ccgttccggc gtccatcggg
     7201 ccaccttgtc ataacggcaa gttttcgtgc cggatcgggc ggtcgctgcc gagactggcc
     7261 acgtcagtcc gtcgctcgcg cccgaccggg ccggccgaag gccggggaac aaccggccga
     7321 aggccgcaca acagccgacg gggccaagcg aaagccgacc gaaggagttc cgatgagtgc
     7381 caccgacgcg gtcacgttct gggacggcgt gtacgccgcc cgtccggcgc ccgacgcgcc
     7441 gcgccccaac gtccgcctgg tcgagacggt caccggcctg ccgcccggcg acgcgctgga
     7501 cctggggtgc ggcagcggcg gcgacgcgct gtggctggcc cggcggggct ggcgggtcac
     7561 ggccgtggac atctccggcg tggcggccga gcggctcgcc gggcacgcac gtgcgcacgc
     7621 cctcggcgac ctggtcgacg ccgtacggca cgacctgcgc gcgtcctttc ccgagggccg
     7681 gttcgacctg gtctgcgccc actacctgca cacccctttc gacctggacc gcgcgtcggt
     7741 cctgcgtacg gccgcgcacg cgctgcgtcc gggcgggcgg ctgctggtcg tcgaccacgg
     7801 ttcgaccgcg ccgtggtcgt gggaccagga ccccgacgcg cggttcccgt ccccggagga
     7861 ggtcgccgcg gacctcgccc tggacccggg gacgtggcgg gtcgagcggg ccgacgcccc
     7921 gcgccggacc gcgaccggcc cgggcgggcg caccgccgag gtcgtcgacc acgtgctgct
     7981 cgtccgccgc gcgggctgac gggccgtacg ccgcggctcc gccggcgccg cacagggcac
     8041 gccctacgcc ccaacgccaa acgccccacg tcgcacgcca cgccaaacgc ctcacgcctc
     8101 acgcctcaag gaggccggtc accatgtcga ccaccccccg cacccaccga cgggacaccc
     8161 cgccgccccg gaccggcggc agcgaggccg agaccctgcg cgggttcctc gactatctgc
     8221 ggacctcgat cgcaggcaag gtcgagggcg ccccggaacc acgggtccgc acggccgccg
     8281 tgccgtcggg caccaacctg ctcgggctgc tccaccacct gacccacgtc gagcgcgccc
     8341 tcttcctcgg ggaagaggtg cggagctggc cggccacctt ccgggccgct cccgaggacg
     8401 gcgtggccga ggtcctcgcc cgctaccgcg cagccgtcga acgggcgaac cgcgtgctcg
     8461 acgcctgcgc cgacctcggc gcaccactcc cccgggcccg tcccggccgc cccgcgccca
     8521 gcgtccgctg ggccctgacg cacatgatcg aggagaccgg ccgacacgcc ggccacgcgg
     8581 atatcctgcg cgaactgatc gacggtacga cggggcgctg acggggcccg tacggtcgaa
     8641 ggggccggga gccgtcaggt cgcgcccgcg gaccggcgtg agcggcggtt gcgccaccag
     8701 gtcaccagcc agaggacgtt gaccccgccc aggaccacca gcaccgtcac cgcgtcggcg
     8761 ttcccggcga ggccgtggcc cggccccagg ccgcgcaccg cgcggaccag gagggcgagg
     8821 tcgacgggca gcgtgaccgc ggccatgaac gccaggcagg cggccgtgcc gaccaccagg
     8881 acgacgctgt agacgcgcac ggcacggcgc tcgtgcgcgg gcaaccgggc actggggtcg
     8941 tcgtcccggc cccccgcacg caccccgcgg cgtacgctcc gcacggcccg caccgatcgg
     9001 cgggcccggt agcgggcgta cgctagaccg tcgccgtaca ggtcgcggca gccggtgagg
     9061 tcctggagga cgaagtacag gtccgtgcgg gtgaagacca tgcactggaa gggcaggggc
     9121 agcagggcca gcagcagggc cgcggccagc agtcggtggg cggtcgtgcc ggtctccgtc
     9181 agggcgaggg tcaggaccag ggacgaggcg acggacagat tgagggcgat tccggccaga
     9241 taggccgtca gccggtgcct gcggggagcg agttcgatgc cgctgatgtc ggtctgcatg
     9301 acgaggaact ggagccgggt gcccagccgc atcttccccg gcacgcccgc cgcacgggcg
     9361 gtgaccaggt gtgccagttc atgggccagc agcagcgtcc acccggccgc cgccccgctc
     9421 agcagcacca cgctgccgtg gcggctccac agcaggtcgc ggtagcccgg cagcagatcg
     9481 gggcggcgca ccaggacgac gacggcggcc accagcagcg ccccgacgag cagcgggagc
     9541 accgggtgca gggcgaggcg gacgtggcgg gggcgcagcc acggcaggga cgcccgcggc
     9601 ggttcggcat ccggcacggg gtggtcgccg atccgggcca cgaaccccag cgcggccagg
     9661 tccccgacga agtccgcgat gtcgaactcc tccccggtct ccgcgcgcag cgactcctcc
     9721 gtgcgccgca cgctcagccc cgcgcccagg agttccaccg cacgcgcccc ggccgcgggc
     9781 agggcgacga aggtccgggt ggtcatgcgg cccacgatcc actcgtcccg gtcccgtcgt
     9841 acggccaggt cgtgcaggag gacacgggtc gtcggcgcga tcgggggcgg gccgtcggcg
     9901 tcggtgccca cggcggcggc gtcggcggcg gcgtcggcct cgctggcggt gtcggaggtg
     9961 tcggcctcgg aggtgtcggc cgcggggccg gcggtgtcgg tcacgacgga ccccggtcgc
    10021 ccgagccggg acgcgcggcc ggggccggat cgggctccac cgggcggcag gccgggcagt
    10081 cggggcgtcg cggtgagcgt tgcaggaccg ggtcgcccgg caccatgagg ttgaggccga
    10141 accggcagcc gggttccacg ggcgggacgc cgcacagcag catcagggcg gcgtgggcca
    10201 gcagcccgcc ggacaggccc gcggtcacgg cgttggccgg attccacggc atccggggcg
    10261 aggccacgtc ctcgtcctgt cccggggcga gccgcaggtc gcgccgctcg atctcggcgt
    10321 cgcgcaggca ctgccagcac gcgccccggc cgggcgtgaa gacccccacg ctgaccagcg
    10381 gcccgcggta gcccgcctcc gcccacggcg tccccgaggc caggcagacc tggttggccc
    10441 acctgcggat cgtggcgggc cggtcggcgg cgagcagcag cgcgtcgtag cccggggagc
    10501 cgtcggggcc atcggcacca tcggcatcgc cggaaccatt ggcaccgccg gcaccggtca
    10561 gcaggtcttc gaggtccgcc gggccgcgca cctcgcgccg ctcgccggtg acctcggcgt
    10621 ccgcgttgag cgcgcgcagc ccggcgagca ccgcgtcgat cttgggtctg cccaggtccc
    10681 gttcgccgaa gagagtctgc cggttgaggt tggacagttc gaccacgtcc ggttcgacgc
    10741 agtgcagccg ccccaccccc gaagccacca ggtcgcgagc ggcggccgag ccggtgcccc
    10801 cggcgccgac cagcaggacc cgggcccggc ggagcagcac ctgcggctcc caggcactgc
    10861 tcctgggccg caggtccatc cagcgcagca gggtcatgcc cctgctgtga cgctcgcggt
    10921 cccgctcgga cagttccgga ggcggcggcg caccggcgtc ctcgacgtac ccggcgtcgg
    10981 tcaggtccgc catcgcctgg acgatgtcag gggcgggcag ccgcagttcc gggtggcgcc
    11041 cggacacctc ggcgacgacg tcagcggcct cccgcgtccc gtccatggcc cggaccagcg
    11101 tccagaccca gccgtcgggg tccttgacct cggcaccgat gccgtggacg acgctgccga
    11161 tccgcacgtg accgtccacg gtccggtagg cgcggtgctc cggcttgatc cggggccgcc
    11221 gcatcgcgtg caccgtcatt ttcgcgccaa cctcgcattt cccaaccgca cggtcgacaa
    11281 gggacgttga caacagtgac ggggtgggcg aacgctggca agggcacaga gtgccccgca
    11341 cacccacagg caccgcgtgt gccagaggca cgacgggcac cacgggtgcc ccgggcacgg
    11401 cgggcatcgc aggcaccatc ggaaggagac ggcatggcga acaagatcga gatccgtccg
    11461 ctggacaaga aggaaaccac cggcgacagc ggtggcaacg gcggcgcctg accggacgcg
    11521 cccgatgcac cgctacctca cggtcgcgga agtcaccgag tcggcgcggc ggctggtctc
    11581 ccggttcccc gggtcctgcc gcctgcgccg gatcggcacg tcccgggccg gccggccgat
    11641 cctgatgctg tccgtgggcc acgggcctcg gcacgtcctg gtggtggccc ggccgcactc
    11701 ggacgagccg gtgggcggcg cgaccgcgct ggccttggcg gagcgcgtgg ccgacggcga
    11761 ccgccggtcc acggcgaccg accccgacac cgtcacctgg gacatcgtcc tgtgcctcga
    11821 cccggacggc gcggccctga gcgagggcct ggaggcggcg acggccggtc ccggacacac
    11881 cctggaccgc tactaccgca ccgccttccg ccccgtcgcg gcggagcagc cggagtgggc
    11941 gcccatcgag gggtggcggc tcccggagag ccgtgcgctg ttcgacgcga tcgacgagct
    12001 gcggcccgtc ctccagtgct cgctgcacag cgtcgacgcc ggtggcacgt gggtccagct
    12061 gacccgtggc cttcccggcc tcgcggcgcc cttccgcgcg tccgccacct cggtcggcgt
    12121 cccggtccag cacggcacgt acgacgccct gtactgggag aacccggccc ccggcatcca
    12181 cgtcctgcct ccgccggaca gcaccgcccg gctggcggcc gggtccgaga acatcggcct
    12241 gtccacctgg tgcgcgcccc ggaggtacgg cggtgtcacg gcgatcgtcg aggtccccct
    12301 gtgggcgacc ggtacggccg acgacctgtc cccgcacccc gacccggccg gtgccctgcg
    12361 cgagctgtcg gggctggtgc gggagggcgg acggcaggtg accgccgtct tcgagaaggc
    12421 ccggggcttc ctgccgccgg ccggggacag cccgcccaga cgcgtactcg agtggatggc
    12481 cgacggcctg tacgacctgg tggccgcatc ctgggagccc ctgctccgac agccggacga
    12541 ggatccccgc acgacgacct caccccggct gacgacggcc gggatcagcg ccctcgaggt
    12601 ggtcgcgcgc cgccagccgc tgcgcgccgc ggggctcctg ctgcggctcc tccgggaggc
    12661 cgacgacccg gccgccgccg gactccgcca cgaactggac gaactcttca ccacctggtg
    12721 cacggagttc gagcagtccc tgcgactgcg ctgggtgccc gtggccgacc aggtggcact
    12781 ccagaccggc acggtggtgg cggcggcgga gtgcgcgctg agacgctgac acgccgtccc
    12841 acagaccggc tggcccactc gcccactcgc ccgctggccc agtcgcccgt tgccccgctg
    12901 acgcgccggc gcggtcctgg accggcggcg cgggtcatcg cgccggcgtg ccggtccggc
    12961 cggttcaggg aagccgcatg tcgatgacgt acttgccgcg gacaccgccg gattcgagcc
    13021 gacggtggac cgccgcgatg tcccccacgg ggaagaccgt gtcgacgacc ggccggatcg
    13081 ttcccgcctc gacggcccgg gtgaggtcgg cgatgcggtc ggccgacggg ttgttgctga
    13141 acatcttgac gcgccgggga gcggcggccg cccgcagggc gatgccgagc atcgaggaga
    13201 cgacgcggtc cgagtcgaag gagagggcga ccagacgccc tccgcgggcc agccgcgcct
    13261 ggtaggcccc caggtcggtg ccgacgacgt ccacgatcac gtcgaagcgg tcgaggtcgc
    13321 cgggccgggt cgtgcggtag tccacggcct cgtccgcacc gagccgggtg atccagtcga
    13381 ggttgcgggc gccggcgagg gcggtcacgt gcgcaccgag cgctttgccc agttgtacgg
    13441 cgatgctgcc gacgccgccg gtggcgccac ggaccaggag cctctcgccc ggctggagtc
    13501 gcgccttgcc gatcagggcc gtcatcgccg tggtgcccac caccggcagg gcggcggcct
    13561 cgaccgggct caggttctcc ggagcgcggg cgagccgttg ttcgggcacg gcgacgtggt
    13621 cggcgatggc gccgaaggtg aggtgcggca tgaggcccca caccgcgtcg ccgacggccc
    13681 aggcgcgtac gccactgccg acggccgcga cccggccggc gaagtcgctg cccaggccgc
    13741 gcgggaagcg ggcgcgggtc acccggcgca tcctgcccgc gcggaaggcg gtctcgccgg
    13801 cgtccacgct cgcggcgtgc acgtcgacga ggacttctcc gggtcccggc cggggcgcgg
    13861 ggatgtcgtc gacacgcaga acgtcgggcg ggccaaatcg gtcgaactgt acggcgcgca
    13921 tgccttcgtc tcctgtgtcg tggacaaaaa cggggtgccc ctccgtttct ctgaatatgg
    13981 gggcaccccc cacttgttgt caaacggtgg agtccgacgg cggtgcgaga atggggtggc
    14041 accccgtttt gccggggagg aaggagacca cgagcgtgac cagggagaac ccgggcccgc
    14101 ccaaacgcgc ggacgcccgc cgcaactacg accggatcct ggaggccgcc gcggccgaag
    14161 tcgcccggcg cggagccgac gcctccctgg aggagatcgc ccggcgggcc ggcgtcggct
    14221 ccgccacgct gcaccgccac ttcccgtccc gctgggacct gctccaggcc gtcttccagg
    14281 agcgcgtggc acagctctgc ggcgaggccc ggtccctggc gggcgagcac ccgcccgcga
    14341 ccgccctgac gacctggctg acgtccctgg cggtcttcgg cgccgtgacg cgcggcgccg
    14401 cccgtgccct gctgcgggca acgggcacga ccgcgtcgac cgcgtcgacc gcgccggatt
    14461 cgcactgcga gcagctgctg atggacgcgg gcggcgacct cctggcccgc gcccagcacg
    14521 ccggaaccgt ccgcgacgac gtcaccgtcg tcgaactggt ctccctcgcc aacgcggtgt
    14581 ccctcgcggc cgagcacacc cccgacgccg cgcggcacgc cacgcggctc atggagatcg
    14641 ccgtcgaggg cctgggcgtg tcgggacacc gcgcccccga gtgacccccg gtcagctcca
    14701 gacccgccgt tcccggccgc gggggtcgtc ggcctgggtc cactcggcgt cgatgcacat
    14761 ggtggcccgg cggtcggtgt cgtacgggtc ccagccgggg tcgccggtcc gggcgaaccg
    14821 gacccaggtg tcgtggacgc ggccggcgag gtccgcgggg gcctcgtcgg ggccgagcag
    14881 ggcgtccggg ccgtggagtt ccggccggtc cgcgaggtcg aagacgaagg gcagttcgac
    14941 cccgtgggtg gcacccagtt cgccgtccag ggcatgggag cgccaggcga accggtaggc
    15001 atacgtggcg gagcgcgggt gggcggcatg ggcgtcggcc agcgcgcggc tgcccgcgcc
    15061 gaacagggcg tcggccatga tggcggagcg cagttccgcg aaggacgccc cggggcgcgc
    15121 cgcgcggtag gtctcgacga gccgctcggg atcggggtgc gagcgtgcgg cggcctcgtc
    15181 gacgtcggcg gcggtcgagg tggcgtacgt gcccaccggg accaggtaga ggttgccctc
    15241 ctcggcgttg gtgccgacga gcaggtcgac gtcggcggcg agaccggcgg cgacggacgc
    15301 ggcgggctgg gtgtccagga ccaggctgaa ggggctgagg ccgatcagcg ggtcgccgtg
    15361 ggtcccggtc cgcaggtcga tgcccgtcag ctgcccggcc gcctcgacga gccgctcgtc
    15421 cgggatcgcg ccgaaggcgt ccacgtgcgg ctcgatgccc agggccccgg ccgcggcccg
    15481 ggtgacacgg gcggcctgct cgggcgtgaa cgcgccccgg ccgctgccgc tctgcacgat
    15541 cgcccggcgg aacagcccgg cggcctcggg ggtggcgagg acgccgccga cgatggtcgc
    15601 cccggccgac tggccgaaga gggtgacgtt gcgcgggtcg ccgccgaagg cggagacgtt
    15661 ctcccgcacc cagcgcagcg cggcgacgac gtcgagcaga ccgcggttgg cgggcgcccc
    15721 ggggacgtcg aggaacccgg cgatcccgag ccggtagttg agggtgacga ggacgacacc
    15781 gtcacgggcg aacgcggaac cgtcgtacag ggcggcccgc gtcgatccgg cgacgaaacc
    15841 gccgccgtgg acgaacacca tgaccggcag ggcgtcaccc ccggcggcgg gcgcgaagac
    15901 gttgacggtg aggtagtcct cgccgcggct ccagccgggg ccgaagtagg gggtcatgtc
    15961 gatgtccccg agcctgcgcg cggactgcgg ggcgctgggt cccggcgcgg tggcgtccag
    16021 tacgccgtcc cacggctcgt gcggccgtgg cggggcgaac cggccggcgc cgcggggcgg
    16081 ggcggcgtag gggatgttca ggaaggtgag ggtgccgtcc cggcgcaggc cgcggacggc
    16141 gccctgcgcg gtggtgacga cgggcccgga atgctggttc atctcgcgtg tctttctcag
    16201 gcctgctcgg tctcggtgta cttggcgaag ggcgcccagc ccttgatggc gaacttgctc
    16261 ccggaacgga cgacttcggc ggcgccgtgg ccgccgaggt gcgcggggaa gacgagggcg
    16321 ttgctgtcga ccgccgcgcc caggagcttg tggcgggtgg cgcgggcttc ggcggggtcc
    16381 tcgcagaaac agctgttggc gtcgggctcg tggatctgga tcgggctgtg catcaggtcg
    16441 ccgacgaaca gggcccggtc ggagccggac tccagccgca gcaccgacga gcccggggtg
    16501 tggccggggg cgaggtcgag gcgcaggtgg gagtcgatgc ggtggctgcc ctcccacagc
    16561 agggcgagac cggcctcgtg cacgggggcg acgctgtcct cgaagacgtt ctggttgccg
    16621 cggcccagca gggtcttgat ctcgttggcg gggttccagt agtcgaagtc cgccttggcc
    16681 atgaggtagg tggcgttggg gaacgtcggt acccaggtcc ggccgtcgag gtaggtgttc
    16741 cagccgacgt ggtcgacgtg caggtgggtg ttgatcacga tgtcgacgtc ctcggggcgc
    16801 accccggcgc gggcgagatt gcccaggaag tcggtgtcca ggcggctcca caccggcgcg
    16861 tacggccggt ccttgtggtt gccgaccccg gtgtcgacca ggatggtcct gccctcgctg
    16921 cgcaggaccc aggtctggat cgcggtgttg acgatgcggg tctcggcgtc caggaagtcc
    16981 gggaccagcc aggaccggtg cgtgtcccac gcctgggccg ggctgtccgg gacgaacgcc
    17041 tcgggcgtca ggtcgacggg accgtagtac tcccggaccc gggtcacggt gacgtcgccc
    17101 agggtgatgg tgtccatggt gcgctccagt tcgatcagtt ctcccgcaag ggtgcgtcgg
    17161 ggtgccgggc ggcggtatgc gtcaggtgac tgcacctggc tgcggcgggc tgcacctggc
    17221 tgcggcgggc cggcgtactg ggccggcggg ccggcccggc ctgcgccgtg cgggtccggg
    17281 gctgggcgga accggggccg gcggaaccgg ggctgggcgg aaccggggcg gggtggcccc
    17341 gccgcccctg ccgcccccac cgcccccgcc gcccctgcgc cacgaccgcg gcgccgtccg
    17401 gctactgtcg gagaagtgcc agtttctgga gcagctgtgg cgaacggtgg aagcgctcga
    17461 gcgggccgga gtccggccgc ggaccccggc ccgaccgtgc tgggccggga aaccgagacc
    17521 gcggacctca tgcggcgcgt cgccgacggc cggtcccgca gcgcggtgct ggtcgtcgag
    17581 ggcgaaccgg gtgtcggcaa gagcgccctg ctcgacctcg ccgtacggcg gacgcgcggt
    17641 gccggccacc gggtgctgcg agcggtcggc agcgagtccg agcagcatct cgccttcgcc
    17701 ggtctgcacc agctgctgcg cccagtactc ggcgacctgg acgcactgcc cgcacggcag
    17761 cgttcctcgc tcggggccgc tctgggactg gccgaccccg ccgcgccccc cgaggccctg
    17821 ctcgtcggcc tggcggtgct gaccctggtg tcggacctcg cggaaccggc gccgctgctg
    17881 gtggtggtcg acgacgccca gtggatcgac cgcgcgtcac tggacgttct ctccttcgtg
    17941 gcgcggcgca tggacagcga gcccgtgacg ctgctgatgg gcgtgcgtgc cgcggccgtg
    18001 ctgcccgggt tcgacaaggg gtacgagcgc ctggtgatcg gtcccctgag cgcggatgcg
    18061 gcgaaccggc tgctcgacga gcagccgggg cgtcccaccg gccgtacccg ggcccggatc
    18121 ctccaggagg cggcgggcaa cccgctggcc ctggtcgagc tggcccgtgc cgccgcgagc
    18181 ggacagccgg agggcgccgg tcgggagggc ccgctgcccg tcaccgaccg gctggagggg
    18241 gtcttcgccc ggcacctgcg gcacctgccc gacaccaccc gccgcgccct gctgctgctc
    18301 gccgccaccg acgcggcgga cgccccggcg gccgcacggg gcctgcccga ggcggccgac
    18361 acggtgtggg cgcccgccga acgggccggt ctcgtacgac gggacagccg cggggtctcc
    18421 ttccggcacc cgctcgtccg ctcggcggtc taccacgccg cacccttcga ggagcgcaga
    18481 agcgcgcacc tggcgctcgc cgggctgctg ggcgaggagc ccgaccggcg tgcctggcac
    18541 ctcgccgccg cgaccgtgcg ccccgacgcg caggtggcgg cggccctcct ggaaaccgcc
    18601 ggccgggccc ggcgccgggg cggccacgcg gccgctgccg ccgccttgga gcgcgccgcg
    18661 cacctcagcc cgcgccgcgc ggaccaggcg cggctgctgg ccgacgccgc gggcgcggcg
    18721 gtcctcaccg gccagctcgg ctgggtggaa cacctggccg ccgaggtcgg caagcgcacc
    18781 gacgacccgg cgctgatcag ccgggccgcg ctggcgacgg ggcagctcat gaccgtgggt
    18841 gcgcaccaca cggccgcctt cgccctgctg tcgcgcattg ccggggaggc ggcggacgcc
    18901 agttcgcccc acctgctgga cgcgctcgcc gcggcggcgg tggtccgcta ctactcgggc
    18961 gaggagtccc agcggcagcg catcgaggcc ctgctctccc aggtgccgga ctccccggcg
    19021 ggtggtgcgc tgcgggcctg gaccctggcc gtctccgatc ccaccggcgc gggagcgtcc
    19081 ctggccccgg cgctgccccg gctgatcgcc gcggccgggg acgacgccgg atccctgatg
    19141 gccctcgccg tggtggcctg gatcctcgac cggaccacgc tggccgccag gaccttcgac
    19201 gaggcgttcg gccgctggca ggccctggga ccgctgccgg ccggtctggc ctgcgcggcc
    19261 ggctggacct atctggagca gggccgctgg gccgaggccc gctcggtggc cgccgagatc
    19321 acggaggtgg cctcgcaggc cggactggtc cacgccgagg catgcgcacg agccctcgac
    19381 gcgaccgtgc tggcgctgct cggtgacccg gccgaggccc gccggaacgc cgagcgggcc
    19441 ctggccctcg tcgatcccct ggagagccgc tccgtcgcgg tcttcgcccg ccgcgccctg
    19501 ggcctcgcgg cggtggccga gggggactac gacaccgcgt acgcgcagtt ccgcgccgcc
    19561 ttcaccgagg acggcgaccc ggtccactac cacgtatccc ccaccgtcct ggccgaactc
    19621 gccgcggcgg ccgtccgcgg ggggcggcgc gaacccgccg cggtcctgct ggagcgatcg
    19681 gcacggcgca cgggcaccag cccgtcggta cgcgcctcct ccctggtcga acgaggccgc
    19741 gccctgctcg ccgaaccgga acacgccgaa cggcacttcc gggcggcgct ggcggacgag
    19801 gcgggcgagc agtggccctt cgagcgggcc cagacccggc tggactacgg agagtggctg
    19861 cgccgccggc gtcgtatcgc ggaggcccgc ccgctgctga ccggagccct cgacacgttc
    19921 cggcggctcg gcgcccgccc ctggatcgaa cgcgcgaagg cggaactccg ggccgccggc
    19981 atcgaggcgg acagcgccgc ccccggcgcg ctcaccgaac tcaccccgca gcaacaacag
    20041 atcgtccggc tcgccgcccg cggcctgacg aaccgcgaga tcggggagaa gctgttcctc
    20101 tccccccgca cggtcggctc ccacctctac cgcgccttcc ccaagctcgg catcaccgcc
    20161 cgcgcccaac tccgcgacac ggtcgacgac gcactggcgg acgccggatc agcgcactgg
    20221 cgcgggtttc acccgtagtc cgccgctcac aacgtccagg cggtgagcag gtcgccgggg
    20281 ccgtacgcgg cgtcgagacc cggagagtcc acgccgctgc gcgagaccgc caccaccggg
    20341 acgggctcgt cggtgagagc ggcccggtgc cgaagaagtg ctgccaggtc gtgccggtcg
    20401 aaggacgacc gctccagcca cttgatggaa ccgacgaaga agagctcctt ggcgacggga
    20461 gcacggtccg ccccgacgac atcgatctcg acgtcgttgg tgcgggtcca gtagccgccc
    20521 actgcggggg ccgcgggtag ccggtcgtcg ggcagtacgc ggaccagcgc ctcgcggatg
    20581 agcggctcga ccgcccggcc gcgccaactg gtccagctct cccggatccg tgccaaggtc
    20641 agatcacctc gtccgcgctc gatctcctcc atggacgggc cgagcaaatg cagccagaac
    20701 cgcaggtaag gatctgccac ccggtagcga cgatccttgg acggacgcag cgacacgggc
    20761 agctccgccg caatgacccg cttctcggcg agcagctcca gcgctcgctg aagcggtgtc
    20821 gccccgattc cgccggcggc acgggcgatg ttggtgaagg tccgctcacc actgccgatg
    20881 gccgccagca ccgtacgcgc ctgggcctga ggcggaaact cggcagccag cgagcgttcg
    20941 gccgacacca gcagggccga gaccggatcg ctcagcgcct ccccgaggaa gtcccacatc
    21001 cccgctcccg gtggccactc cgcgcagatc agcggcagcc cgccggtgac cagcgcggcg
    21061 tcgaaggctt ccgccggatc caggccgagc atctgcccca cctcggcagg gttgagcggc
    21121 cccagcacca tctcacggcc gcgctggtgg aaggggcgtc cgtagctgtt cagtgcctcc
    21181 atcatcgaca gatcggagcc gatgaggacc agcagtaccg gcttcgtctc cagtacccg
//
