LOCUS       NZ_KZ195574            21086 bp    DNA     linear   CON 06-SEP-2024
DEFINITION  Streptomyces sp. CS113 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ195574
VERSION     NZ_KZ195574.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS113
  ORGANISM  Streptomyces sp. CS113
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8695358)
  AUTHORS   Malmierca,M.G., Gonzalez-Montes,L., Perez-Victoria,I., Sialer,C.,
            Brana,A.F., Garcia Salcedo,R., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Searching for Glycosylated Natural Products in Actinomycetes and
            Identification of Novel Macrolactams and Angucyclines
  JOURNAL   Front Microbiol 9, 39 (2018)
   PUBMED   29441046
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8695358)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Searching for glycosylated natural products in actinomycetes
            isolated from leaf-cutting ants: activation of two silent clusters
            and identification of a novel macrolactam
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8695358)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAY-2017) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 78.17x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002188365.1-RS_2024_09_06
            Annotation Date                   :: 09/06/2024 02:31:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,790
            CDSs (total)                      :: 7,719
            Genes (coding)                    :: 7,614
            CDSs (with protein)               :: 7,614
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 1 (5S, 16S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 105
            CDSs (without protein)            :: 105
            Pseudo Genes (ambiguous residues) :: 0 of 105
            Pseudo Genes (frameshifted)       :: 35 of 105
            Pseudo Genes (incomplete)         :: 81 of 105
            Pseudo Genes (internal stop)      :: 4 of 105
            Pseudo Genes (multiple problems)  :: 15 of 105
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:56:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2987439
            Orig. end                         :: 3008525
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ195574.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Salas's laboratory, A.
            Microbiology, University of Oviedo, Spain.
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="20"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11086)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(55..70)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.16"
                     /tool="antismash"
     gene            204..968
                     /locus_tag="B9W62_RS12825"
                     /old_locus_tag="B9W62_12855"
     CDS             204..968
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973740.1"
                     /locus_tag="B9W62_RS12825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12855"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_003973740.1"
                     /transl_table=11
                     /translation="MSTDVSSAENEGGATVRTARVPKYYRLKKHLLDMTRTQTPGTPVP
                     PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA
                     QGLEPTSQLLDIGYITADDRLAGLLDITAGGRVLRIERLRMANGEPMAIETTHLSAKRF
                     PALRRSLVKYTSLYTALAEVYDVHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRH
                     SQDRTGQPVEWVRSVYRGDRYKFVARLKRPQD"
     misc_feature    1018..1032
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.75"
                     /tool="antismash"
     gene            1103..1393
                     /locus_tag="B9W62_RS12830"
                     /old_locus_tag="B9W62_12860"
     CDS             1103..1393
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984454.1"
                     /locus_tag="B9W62_RS12830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12860"
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_179235466.1"
                     /transl_table=11
                     /translation="MSEDTEVSREPVVTPVRVVIGICLVAPFVAMLWVGSYTKTDPAFI
                     GIPFFYWYQMAWVLISTLLTMTAYKLWQRDQRGRAAHSAAAPSSPKGGESR"
     gene            1390..3000
                     /gene="mctP"
                     /locus_tag="B9W62_RS12835"
                     /old_locus_tag="B9W62_12865"
     CDS             1390..3000
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006848 - pyruvate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="mctP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444565.1"
                     /locus_tag="B9W62_RS12835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12865"
                     /product="monocarboxylate uptake permease MctP"
                     /protein_id="WP_087807307.1"
                     /transl_table=11
                     /translation="MNDGVNGVALAVFIFFFVLVTAMGFLAARWRRAENEHSLDEWGLG
                     GRSFGTWVTWFLLGGDLYTAYTFVAVPAAIYAAGASGFFAVPYTILVYPLIFTFLPRLW
                     SVSHKHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGG
                     EDTNWFIKDLPLLIAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGG
                     FDDIFASASDKFTETGKGGVVPDAGGQWTYATLALGSALALFMYPHSITATLSSRSREV
                     IRRNTTILPLYSLMLGLLALLGFMAIAAGVKVENGQLAIPQLFENMFPDWFAGVAFAAI
                     GIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPAQETKVSKLVSLLVKVGALIFVLGM
                     DKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALLGGWAVGMVYGTVAAYGVASPT
                     QKHFGGSSDEIPGIGEIGYIGLTAFVLNVLVTVVLTFVLRAAKAPDGVDETKPSDYTAD
                     AGDPGVQVELPPATAGSSH"
     gene            3106..3612
                     /locus_tag="B9W62_RS12840"
                     /old_locus_tag="B9W62_12870"
     CDS             3106..3612
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326961.1"
                     /locus_tag="B9W62_RS12840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12870"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_087811880.1"
                     /transl_table=11
                     /translation="MDFVIRRATAEEYDTLGEITAQAYLRDGLLDFGESDAYLDELRNV
                     AKRATAAEVLDAVADGRVLGGVTFVPSGGPMADIARPGEAEIRMLAVAREARGRGAGEA
                     LVRACVDRARAVEGCRSVVLSTQATMRTAHRLYERLGFVRTPDRDWNPVPELDDIMLLT
                     YELTL"
     misc_feature    3649..3663
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 25.12"
                     /tool="antismash"
     regulatory      3674..3835
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    3680..3694
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     gene            3963..6338
                     /locus_tag="B9W62_RS12845"
                     /old_locus_tag="B9W62_12875"
     CDS             3963..6338
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444560.1"
                     /locus_tag="B9W62_RS12845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12875"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_087807308.1"
                     /transl_table=11
                     /translation="MTIAPADPASATPATATGEPDGPGAALLRTLTGLTADLQGADPGR
                     VAAAALRGRSAHADEAELRELATEAAAGLISEDPVYSRLAARLLTIGIRAEAASQGVVT
                     FTDSVATGHREGLIADRTAAFVRLHAERLDALIDRAADDRFGYFGLRTLYSRYLLRHPI
                     TRKAVETPQHFLLRVAAGLAEDDTVRAVDEVAALYGLMSRLDYLPSSPTLFNSGTRHAQ
                     MSSCYLLDSPKDELDSLYDRLHQVARLSKHAGGIGIAYSRVRARGSLIRGTNGHSNGIV
                     PFLKTLDASVAAVNQGGRRKGAAAVYLETWHADVEEFLELRDNTGEDARRTHNLNLAHW
                     IPDEFMRRVDADGTWSLFSPADVPELTDLWGEEFDAAYRRAEEAGLARRTLPARELYGR
                     MMRTLAQTGNGWMTFKDTANRTANQTATPGHVVHSSNLCTEILEVTDDGETAVCNLGSV
                     NLGAFADPASGDMDWERLDATVRTAVTFLDRIVDINFYPTEQAARSNARWRPVGLGAMG
                     LQDVFFQLRLPFDSPEAKALSTRIAERIMLAAYETSADLAERSGPVPAWEKTRTAQGVL
                     HPDHYGVEPAWPERWAALRERMATTGLRNSLLLAIAPTATIASIAGVYECIEPQVSNLF
                     KRETLSGEFLQVNSYLVDDLKRLGVWDARTREALREANGSVQGFSWIPEDVRALYRTAW
                     EIPQRGLIDMAAARTPYLDQAQSLNLFLETPTIGKLSSMYAYAWKQGLKTTYYLRSRPA
                     TRIARAAARATTVPVQAGPDSEAVACSLENPESCEACQ"
     gene            6338..7369
                     /locus_tag="B9W62_RS12850"
                     /old_locus_tag="B9W62_12880"
     CDS             6338..7369
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992855.1"
                     /locus_tag="B9W62_RS12850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12880"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_087807309.1"
                     /transl_table=11
                     /translation="MTTEIPATRATKNLLDPGFELTLRPMRYPDFYERYRDAIKNTWHV
                     EEVDLHSDVADLAKLSPEEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLS
                     RQLFEEAVHVQFYLTLLDTYLPDPEDRAAAFAAVENIPSIREKAGFCFKWMDSVESIDR
                     LETQADRRRFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMH
                     MSFAFDVVDTVRKEEPELFDDRLRQEVTDMLREAVEAELQFARDLCGDGLPGMNTDSMR
                     QYLECVADQRLTRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGTVDLD
                     EDF"
     gene            7647..8615
                     /locus_tag="B9W62_RS12860"
                     /old_locus_tag="B9W62_12890"
     CDS             7647..8615
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030121.1"
                     /locus_tag="B9W62_RS12860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12890"
                     /product="GlxA family transcriptional regulator"
                     /protein_id="WP_087807311.1"
                     /transl_table=11
                     /translation="MLQNVAAVLLDGAHPFELGVICEVFGIDRSDEGLPGYDFAVVSAE
                     GPRLSTHVGGLTVSTPYGLERLEEADLIAVPAGSDFVRREYPPELLEALRRATARGTRV
                     LSVCSGVFVLGAAGLLDGRRCAVHWHHAAELARQHPRARVEPDVLYVDEDPVITSAGTA
                     AGIDACLHIVRKEQGPEVANRIARRMVVPPHRDGGQAQYIERPLPRSSCDTVGEVLAWM
                     EQHLDEEVTVEQLAVRAHMSPRTFARRFQQETGTTPYRWILRQRVLLAQRLLEATDETM
                     DSIAWRAGFGTAAALRHQFTRALGTTPHAYRRTFRGPEAAA"
     gene            complement(8628..10004)
                     /locus_tag="B9W62_RS12865"
                     /old_locus_tag="B9W62_12895"
     CDS             complement(8628..10004)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326965.1"
                     /locus_tag="B9W62_RS12865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12895"
                     /product="cytochrome P450"
                     /protein_id="WP_087807312.1"
                     /sec_met_domain="p450 (E-value: 1.2e-69, bitscore: 234.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESVNPETRAQPARELRVPPVAGGGVPLLGHGWRLARDPLAFM
                     SQLRDHGDIVRIKLGPKTVYAVTNPELTGALALNPDYHIAGPLWESLEGLLGKEGVATA
                     NGPLHRRQRRTIQPAFRLDAIPAYGPIMEEEAHALTERWQPGETVDATSESFRVAVRVA
                     ARCLLRGQYMDERAERLCVALATVFRGMYRRMVVPLGPLYRLPLPANRRFNDALADLHL
                     LVDEIIAERRASGQKPDDLLTALLEAKDDNGDPIGEQEIHDQVVAILTPGSETIASTIM
                     WLLQALADHPEHADRIRDEVEAVTGGRPVAFEDVRGLTHTGNVVVEAMRLRPAVWVLTR
                     RAVAESELGGYRIPAGADIIYSPYAIQRDPKSYDDNLEFDPDRWLPERAKNVPKYAMKP
                     FSAGKRKCPSDHFSMAQLTLITAALATKYRFEQVAGSNDAVRVGITLRPHDLLVRPVAR
                     "
     gene            complement(10001..11086)
                     /gene="cyc1"
                     /locus_tag="B9W62_RS12870"
                     /old_locus_tag="B9W62_12900"
     CDS             complement(10001..11086)
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992851.1"
                     /locus_tag="B9W62_RS12870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12900"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_087811881.1"
                     /sec_met_domain="T1TS (E-value: 9.7e-63, bitscore: 211.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHAFSHGTTATPTAIAVPPSLRLPVIEAAFPRQLHPYWPRLQETT
                     RTWLLEKRLMPADKVAEYADGLCYTDLMAGYYLGAPDEVMQAIADYSAWFFVWDDRHDR
                     DIVHGRPGAWRRLRGRLHTALDSPGDHLHHEDTLVAGFADSVRRLYAFLPGTWNARFAR
                     HFHAVIEAYDREFHNRTRGIVPGVEEYLQLRRLTFAHWIWTDLLEPASGCELPDAVRKH
                     PAYRRAALLSQEFAAWYNDLCSLPKEIAGDEVHNLGISLITHHSLTLEEAIGEVRRRVE
                     ECITEFLAVEQDALRFADELADGTVRGKELGGAVRANVGNMRNWFSSVYWFHHESGRYM
                     VDSWDDRSTPPYVNNEAAGEK"
     misc_feature    complement(10202..10204)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11356..12006)
                     /gene="def"
                     /locus_tag="B9W62_RS12875"
                     /old_locus_tag="B9W62_12905"
     CDS             complement(11356..12006)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="B9W62_RS12875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12905"
                     /product="peptide deformylase"
                     /protein_id="WP_087807313.1"
                     /transl_table=11
                     /translation="MAQQDTDQQHPGVLPVDDEGFVVDTQDCEEREADWRGRGTSRPIT
                     VVGNPVLHKECEDVTDFGEEFQQLVADMFASQRTAEGVGLAANQIGVSKKVFVYDCPDD
                     EGVRHVGVVCNPKLVELPADRRRLDDSNEGCLSVPTAYAPLARPDYAEVTGQDEKGNPV
                     KVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAENEPRYPVVAND"
     gene            complement(12094..13074)
                     /locus_tag="B9W62_RS12880"
                     /old_locus_tag="B9W62_12910"
     CDS             complement(12094..13074)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="B9W62_RS12880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12910"
                     /product="hypothetical protein"
                     /protein_id="WP_087807314.1"
                     /transl_table=11
                     /translation="MRIFGKARHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLDRDTGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLRTPGDATDAGEPLGMDLGSAAVRLSPEGEAEVVWGRRLDPARVEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTSAGHSYPVFDEIELWAPSPVPTWVVLLEAATEADRD
                     ALEQLASDAGFAAEDWSSSVRLLCRMCSESRMPSDEGEGEHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGVAAPAGLVKGLLDGWVADSPDSRDWRDLEEVC"
     gene            complement(13188..14453)
                     /locus_tag="B9W62_RS12885"
                     /old_locus_tag="B9W62_12915"
     CDS             complement(13188..14453)
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973753.1"
                     /locus_tag="B9W62_RS12885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12915"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_087807315.1"
                     /transl_table=11
                     /translation="MTPSPPPAQPPPSAAPLLVPGCAGILALGCLASVLGSGPVQRPVA
                     LAFGGLVVLGELTRRTGAEAREAAPLGAAGALAYALLGDVAGQPAQHGVAQTVTVVLAA
                     SLLGSVPYVARGSGPVLDHLARRVLTVGFAAVCFRPLAQQGVFDDWSGPAHALLLLALL
                     ALTSLCDAVLAAAPAHARTGWPFGPLLREELRGMVGITSAVCATGAVMALAVSVAGLWA
                     LPVFCVPLLLAQLSYRRYAAVRATYRQTIASLARATEIAGYTPAGHARRVAGLGVAVGR
                     DLGLSGAELTVLEYAALMHDIGQLSLVDPVPAGATAGLPVTEQRRIALLGGAVVRQTGV
                     DAAVAVVVERQADPCREQPVAARIVRVVNAYEEKARDAGPGGVLTALEELRLATASDYA
                     PEVVEALARVLARGSLTGPAAG"
     gene            complement(14450..15775)
                     /locus_tag="B9W62_RS12890"
                     /old_locus_tag="B9W62_12920"
     CDS             complement(14450..15775)
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973754.1"
                     /locus_tag="B9W62_RS12890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12920"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_087807316.1"
                     /transl_table=11
                     /translation="MDAVPARARVYVTGVALAALLCLWPLPSVHAPWWAVLLLAGLYAG
                     SELVARSRFVGTCYPVLLAGAFLLPPPAAALVALPGALLSPVPRRPFGLRRLWRAAQLT
                     LAVWAAAGVHWRLGGRDAVVEPAFPYALVPAGAAVLAFCLVLTVLDGGIRALADHVPPS
                     RAWRGLLSRSLAPIAVHGLAGLMMAVLWRSPYGPVAALLVLLPMCVAWWAFAQYHRERA
                     AHQATIRALVQAVDIKDGYTRGHSERVGQASMMIARELGMDDERVETLRFAGILHDVGK
                     LGVPTRLLRKDGPLTPEERRVIELHPEYGHEMVRGIRFLGEARAAVLHHHERLDGSGYP
                     YGLAGDRIPESARVVAVADAFDAMTSTRSYRRARPVAAALEELQRCAGGQFDPRMVRAL
                     VHALGRHGWRPSVTADGTPALPAAPSPGRGEGARDSVGRGAP"
     gene            complement(15903..16217)
                     /gene="rsrA"
                     /locus_tag="B9W62_RS12895"
                     /old_locus_tag="B9W62_12925"
     CDS             complement(15903..16217)
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326971.1"
                     /locus_tag="B9W62_RS12895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12925"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_059300663.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEILDHLYEFLDKEMPDSDCVKFEHHFEECSPCL
                     EKYGLEQAVKKLVKRCCGQDDVPGDLRAKVMGRLDLIRSGQSVPEHDVTAAPSSAPQES
                     "
     gene            complement(16214..16897)
                     /gene="sigR"
                     /locus_tag="B9W62_RS12900"
                     /old_locus_tag="B9W62_12930"
     CDS             complement(16214..16897)
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="B9W62_RS12900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12930"
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_087807317.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTEHGQAEQPEGRGTDAESTAERSARFERDALEFLD
                     QMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRKK
                     QREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKQALQAIPEEFRIAV
                     YLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARDRGLVPAGAGESNEA
                     KGSGS"
     misc_feature    complement(16860..16875)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.19"
                     /tool="antismash"
     gene            complement(17176..17811)
                     /locus_tag="B9W62_RS12905"
                     /old_locus_tag="B9W62_12935"
     CDS             complement(17176..17811)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973757.1"
                     /locus_tag="B9W62_RS12905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12935"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_087807318.1"
                     /transl_table=11
                     /translation="MTETVETDAGPARITWHPAERPRLVLAASHGAGGGIEARDLKALA
                     AALPAHGVSVALVEQPWRVAGKKLAPAPKTLDTGWRGVWPALTAPGLPVVSGGRSAGAR
                     VACRTAAELGARAVLALSFPLHPPGKPEKSRAEELLGSGVPTLVVQGGNDPFGRPREFP
                     EAPAGTYELIEVPYGDHGFAVPKRAEIGQEEALELITDGVLKWTGSLG"
     gene            complement(17834..18649)
                     /locus_tag="B9W62_RS12910"
                     /old_locus_tag="B9W62_12940"
     CDS             complement(17834..18649)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="B9W62_RS12910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12940"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_087807319.1"
                     /transl_table=11
                     /translation="MCGRYAASRRPEDLAGIFEIEKWEPKESLDPDYNVAPTKEVHAVL
                     DRPLKDVEDPKPVRQLRKLKWGLVPSWSKTSEGAARMINARAETVHEKPSYRRAFSTRR
                     CILPADGYYEWVTGKQERDLEVEGRKKRPRKQPYFVTPADGSVFAMAGLYEFWRDKTLP
                     DDHPQAWWVTCSVITTEAETTPLAVAPADGPHALADIHPRMPLMLTPDRWDAWLDPART
                     DPDELTSLLAPPPAGLLRAYPVSTTVSNVRNNGPELLKELEGPEEGTLF"
     gene            18754..19476
                     /locus_tag="B9W62_RS12915"
                     /old_locus_tag="B9W62_12945"
     CDS             18754..19476
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973759.1"
                     /locus_tag="B9W62_RS12915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12945"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_087807320.1"
                     /transl_table=11
                     /translation="MDHLATASLTSLWDEVSGTQPDPDLWVVIATLVAALAVVVTRGSW
                     RIARNAITIAHEGGHGLVALLTGRTLTGITLHSDTSGLTVSRGKPHGIGMILTAVAGYT
                     APPLLGLGGAALLAAGRITLLLWLATALLVALLVMVRNAYGVLTVVVTGGTFVLVSWLA
                     GPQVQAAFAYAVVWFLLLGGVRPAFELQAKRSRGGAGDSDADQLARLTHAPAGVWFFLF
                     HAVSLCSLIGGGRWLLEL"
     gene            19600..20916
                     /gene="aroA"
                     /locus_tag="B9W62_RS12920"
                     /old_locus_tag="B9W62_12950"
     CDS             19600..20916
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522882.1"
                     /locus_tag="B9W62_RS12920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12950"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_087807321.1"
                     /transl_table=11
                     /translation="MTVNPAHTTLWPAPHASGAVDATVHVPGSKSVTNRALVLAALASE
                     PGWLRRPLRSRDTLLMAEALRTMGVEIEEGVGPEGTGEFWRVIPAGLRGPATVDVGNAG
                     TVMRFLPPVATLADGTVRFDGDPRSYERPLHGVIDALRALGARIDDDARGALPMTVHGG
                     GALEGGPVEIDASSSSQFVSALLLSGPRFNQGVEVRHTGSALPSMPHIRMTVDMLRAVG
                     AQVDTPESGGEPNVWRVTPGALLGRDLTIEPDLSNAQPFLAAALVTGGRVVIPDWPSRT
                     TQPGDRLREIFTEMGGSCELTDYGLVFTGSGAVRGIDVDLGEVGELTPGIAAVAALADS
                     PSTLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLHIRPRRLHGGVFHTYEDHRM
                     ATAGAIIGLAVEGVQIENVATTAKTLPDFPDLWTGMLGA"
ORIGIN
        1 gaatgacgtg ccacgacggc tccgaacgcg cgtaccagcg acgcctgacc catctgtgga
       61 ctagaccaag ggtgttcccg cgggtataca gaggggatca cggagcgtgc gggggccatc
      121 ccggcacgaa gccgtgccac gatgtgagcc gtggccgaca gggatagcgg tcgcttcggc
      181 acccggagcc gggaaggcag agcatgagca ccgacgtcag cagtgcggag aacgagggtg
      241 gggcgaccgt ccgtaccgcg cgcgtgccca agtactaccg tctgaagaag catctgctgg
      301 acatgacccg gacccagacc ccgggcaccc cggtcccgcc cgagcgcacc ctggccgccg
      361 agttcgacac ctcgcgcacc acggtgcgcc aggcccttca ggaactggtc gtcgagggcc
      421 gcctggagcg catccagggc aagggcacct tcgtcgccaa gcccaaggtg tcgcaggcgc
      481 tgcaactcac ctcgtacacc gaggacatgc gggcccaggg cctcgagccc acctcgcagc
      541 tgctggacat cggctacatc accgccgacg accggctcgc cgggctgctg gacatcacgg
      601 ccggcggccg ggtgctgcgc atcgagcggc tgcgcatggc caacggcgag ccgatggcga
      661 tcgagaccac ccacctcagc gccaagcgct tcccggccct gcgccgctcc ctggtgaagt
      721 acacgtccct ctacaccgcg ctcgccgagg tgtacgacgt ccatctcgcc gaggccgagg
      781 agaccatcga gacctccctg gccaccccgc gcgaggccgg tctgctcggc accgacgtgg
      841 gcctgcccat gctgatgctc tcccggcact cgcaggaccg caccggccag ccggtggagt
      901 gggtgcgctc cgtgtaccgc ggcgaccgct acaagttcgt ggcccgcctc aagcggcccc
      961 aggactagac cagcacccgc ccgcgcggcc ccagattgcg gttggggacc gatatacgga
     1021 cgaggtcttc cgctgtctcg acaccgtcac ctacatttcg tgcgcactgc acgaggtgat
     1081 cagcgagggg acggagccgc gcatgtcaga agacacagaa gtgagcagag agccggtggt
     1141 gacgccggtg cgcgtcgtca tcggcatctg cctcgtcgca ccgttcgtcg ccatgctctg
     1201 ggtcggttcg tacacgaaga cggacccggc cttcatcggc atcccgttct tctactggta
     1261 ccagatggcc tgggtgctga tctccaccct gctgacgatg accgcctaca agctgtggca
     1321 gcgcgaccag cgcgggcgcg cggcccactc cgccgccgcc ccctcctcgc cgaagggcgg
     1381 tgagtcgcga tgaacgacgg cgtgaacggc gtcgcactcg ccgtcttcat cttcttcttc
     1441 gtcctcgtca ccgccatggg cttcctggcc gcccgctggc gccgggccga gaacgagcac
     1501 agcctcgacg agtggggcct gggcggccgc tcgttcggca cctgggtcac ctggttcctg
     1561 ctgggcggcg acctgtacac cgcgtacacc ttcgtggccg tcccggcggc gatctacgcg
     1621 gcgggcgcgt ccggcttctt cgcggtgccg tacacgatcc tggtctaccc gctgatcttc
     1681 accttcctgc cccgcctgtg gtcggtctcg cacaagcacg ggtacgtgac gacctcggac
     1741 ttcgtccgcg gccggttcgg ctccaagggc ctgtcgctgg cggtggccgt caccggcatc
     1801 ctggcgacca tgccgtacat cgcgctccag ctggtcggca tccaggccgt gctcgacgtg
     1861 atgggcgtcg gcggcggcga ggacaccaac tggttcatca aggacctgcc gctgctgatc
     1921 gccttcggcg tgctcgcggc gtacacgtac tcgtcggggc tgcgggcgcc cgcgctgatc
     1981 gcgttcgtga aggacacgct gatctacatc gtcatcgcgg tggcgatcat ctacatcccg
     2041 atcaagctgg gcgggttcga cgacatcttc gcgtcggcga gcgacaagtt caccgagacg
     2101 ggcaagggcg gggtggtgcc ggacgcgggg ggccagtgga cgtacgcgac cctcgccctc
     2161 ggttcggcgc tcgcgctctt catgtacccg cactcgatca ccgccacgct gtcctcgcgc
     2221 agccgtgagg tgatccgccg caacaccacg atcctgccgc tgtactcgct gatgctgggt
     2281 ctgctcgcgc tgctcggctt catggcgatc gcggccgggg tcaaggtgga gaacggccag
     2341 ctggcgatcc cgcagctgtt cgagaacatg ttcccggact ggttcgcggg cgtcgccttc
     2401 gcggcgatcg gcatcggcgc cctggtcccg gcggcgatca tgtcgatcgc ggccgcgaac
     2461 ctcttcaccc gcaacatcta caaggacttc atcaagcccg acgccacccc ggcacaggag
     2521 acgaaggtct ccaagctggt gtcgctgctg gtgaaggtgg gcgcactgat cttcgtcctg
     2581 ggcatggaca agacggtcgc gatcaacttc cagctgctgg gcggcatctg gattttgcag
     2641 accttcccgg ccctggtcgg cggcctgttc acccgctggt tccaccgctg ggcgctgctc
     2701 ggcggctggg cggtcggcat ggtctacggc acggtcgccg cctacggtgt cgcctcgccg
     2761 acgcagaagc acttcggcgg ctcctccgac gagatccccg gcatcggcga gatcggctac
     2821 atcgggctca ccgccttcgt gctgaacgtc ctggtcaccg tggtcctgac cttcgtcctg
     2881 cgggcggcca aggcgcccga cggcgtcgac gagaccaagc cgagcgacta cacggcggac
     2941 gccggcgacc ccggcgtcca ggtggaactg ccgccggcca cggcgggcag ctcgcactag
     3001 cggcgcccct tcagcgggcc gtcggagaaa tccggcggcc cgttgccgta cccgtcggag
     3061 aaatccggcg gcccgttgcc gtacccgtcg ggcacactcg gcgtcatgga cttcgtgatc
     3121 cggcgggcga cggccgagga gtacgacacc ctcggcgaga tcaccgcgca ggcctacctg
     3181 cgcgacggcc tcctcgactt cggggagagc gatgcgtatc tcgacgagct gaggaacgtg
     3241 gccaagcgcg cgaccgccgc cgaggtgctg gacgccgtgg ccgacggccg ggtgctcggc
     3301 ggcgtgacct tcgtgccgtc cggcggcccc atggcggaca tagcgcgccc cggcgaggcc
     3361 gagatacgca tgctcgccgt cgcccgcgag gcgcgcggcc gcggggcggg cgaggccctc
     3421 gtgcgcgcct gcgtcgaccg ggcccgggcc gtcgagggct gccggagcgt cgtgctgtcg
     3481 acccaggcca ccatgcgcac cgcccaccgc ctctacgagc gtctgggctt cgtccgcacg
     3541 cccgaccgcg actggaatcc cgtgccggag ctggacgaca tcatgctgct cacctacgaa
     3601 ctgacgctct gacacgctcg cggcaccccg gcacggcacc ccgccgggac acaacatctg
     3661 ggggtgctcg cgccacccgg cacaagatgt atgctcgtgc tcgctgtcgc cgcaggggaa
     3721 tccggtgcga atccggaact gtcccgcaac ggtgtacttg cgtgcatccg tacgtcttcg
     3781 cacgtgcgcg cacgcctgtc cagtccgagg acctgccgac agtgcgcccg gccgccctgg
     3841 cccgggtgcc atgacgtccg ggcctcgtgg agtgggccgg tggacgcgac gccgcgtgcg
     3901 ctcgtgagct gccccctgcc ctccctccgc caggccccgt gccgagcgag ggagtgctcc
     3961 acgtgaccat cgcgccagcc gatccggctt cagcgacccc ggcgacggcg accggggaac
     4021 ccgacggacc cggtgccgcc ctgctgcgga ccctgaccgg gctgaccgcc gacctccagg
     4081 gcgccgaccc cggccgggtg gccgccgccg cgctgcgcgg ccggtccgcc cacgcggacg
     4141 aggccgagct gcgggagctg gccaccgagg cggccgccgg tctgatctcc gaggacccgg
     4201 tctactcccg gctggccgcc cgcctgctga ccatcggcat ccgcgccgag gcggcctccc
     4261 agggcgtcgt caccttcacc gactccgtcg ccaccggcca ccgcgagggc ctgatcgccg
     4321 accgcaccgc cgccttcgta cggctgcacg cggaacgcct ggacgcgctg atcgaccggg
     4381 ccgccgacga ccgcttcggc tacttcgggc tgcgtacgct ctacagccgc tacctgctcc
     4441 ggcatccgat cacccgcaag gccgtcgaga cgccccagca cttcctgctg cgggtggccg
     4501 ccggactcgc cgaggacgac acggtgcgcg cggtggacga ggtcgccgcg ctgtacgggc
     4561 tgatgagccg cctggactac ctgccctcct cccccaccct cttcaactcc ggcacccggc
     4621 acgcccagat gtcgtcctgc tacctcctgg actcccccaa ggacgagctg gactccctct
     4681 acgaccgcct ccaccaggtc gcccgcctct ccaagcacgc cggcggcatc ggcatcgcct
     4741 actcccgcgt ccgcgcccgg ggttcgctga tccgcggcac caacgggcac tccaacggca
     4801 tcgtcccgtt cctgaagacg ctggacgcct cggtcgccgc cgtgaaccag ggcggccggc
     4861 gcaagggcgc cgccgccgtc tacctggaga cctggcacgc ggacgtcgag gagttcctgg
     4921 agctgcggga caacaccggc gaggacgccc gccgtacgca caacctgaac ctcgcgcact
     4981 ggatcccgga cgagttcatg cgccgggtgg acgccgacgg gacctggtcg ctgttctccc
     5041 cggccgacgt gccggagctg accgacctgt ggggcgagga gttcgacgcc gcctaccgca
     5101 gggcggagga ggcggggctc gcccgcagga cgctgcccgc ccgtgagctg tacggccgca
     5161 tgatgcgcac cctcgcgcag accggcaacg gctggatgac cttcaaggac accgccaacc
     5221 gcaccgcgaa ccagaccgcg acccccggcc acgtcgtcca ctcctccaac ctctgcacgg
     5281 agatcctgga ggtcaccgac gacggggaga cggcggtctg caacctgggc tcggtcaacc
     5341 tgggcgcctt cgccgacccc gcgagcggcg acatggactg ggagcgcctg gacgccaccg
     5401 tccgcaccgc cgtcaccttc ctggaccgga tcgtcgacat caacttctac ccgaccgagc
     5461 aggccgcccg ctccaacgcc cgctggcgcc cggtcggcct cggcgcgatg ggcctccagg
     5521 acgtcttctt ccagctccgg ctgcccttcg actcccccga ggcgaaggcg ctgtccaccc
     5581 gcatcgccga gcggatcatg ctcgccgcgt acgagacgtc cgccgacctc gccgagcgca
     5641 gcggtccggt gccggcctgg gagaagaccc gtacggccca gggggtgctc caccccgacc
     5701 actacggcgt cgagcccgcc tggccggagc gctgggccgc gctgcgcgag cgcatggcca
     5761 ccaccgggct gcgcaactcc ctgctcctgg ccatcgcgcc gaccgcgacc atcgcctcca
     5821 tcgccggggt ctacgagtgc atcgagccgc aggtgtccaa cctgttcaag cgcgagacgc
     5881 tgtccggcga gttcctccag gtcaactcct acctggtgga cgacctcaag cggctcggcg
     5941 tgtgggacgc ccgcacccgt gaggcgctgc gcgaggccaa cggctcggtg cagggcttct
     6001 cctggatccc cgaggacgtg cgggcgctgt accgcaccgc ctgggagatc ccgcagcgcg
     6061 gcctgatcga catggccgcc gcccgcaccc cgtacctcga ccaggcccag tcgctgaacc
     6121 tgttcctgga gacgccgacc atcgggaagc tctcctcgat gtacgcctac gcctggaagc
     6181 agggcctgaa gaccacgtac tacctgcgct cccgcccggc gacccggatc gcccgcgccg
     6241 cggcccgcgc caccaccgtc cccgtgcagg ccggccccga ctccgaagcg gtcgcctgct
     6301 ccctggaaaa ccccgagtcc tgcgaggcct gccagtaatg accaccgaga tccccgcgac
     6361 ccgcgccacc aagaacctgc tcgacccggg cttcgagctg accctgcgcc ccatgcgcta
     6421 cccggacttc tacgagcgct accgggacgc catcaagaac acctggcacg tcgaggaggt
     6481 cgacctccac tcggacgtcg ccgacctcgc gaagctcagc cccgaggagc agcacctgat
     6541 cggccgtctg gtggccttct tcgccaccgg cgactcgatc gtcgcgaaca acctggtgct
     6601 gaccctgtac aagcacatca actcccccga ggcgcggctg tacctgtccc gccagctctt
     6661 cgaggaggcc gtccacgtcc agttctacct gacgctcctc gacacctatc tgcccgaccc
     6721 ggaggaccgc gccgcggcct tcgcggccgt ggagaacatc ccgtccatcc gggagaaggc
     6781 cgggttctgc ttcaagtgga tggactcggt ggagtcgatc gaccggctgg agacgcaggc
     6841 cgaccggcgc cgcttcctgc tcaacctgat ctgtttcgcg gcgtgcatcg agggcctgtt
     6901 cttctacggc gccttcgcct acgtctactg gttccgcagc cggggtctgc tgcacggcct
     6961 ggccaccggc accaactggg tgttccggga cgagacgatg cacatgtcct tcgccttcga
     7021 cgtcgtcgac accgtgcgca aggaggagcc ggagctgttc gacgaccggc tccggcagga
     7081 ggtcaccgac atgctgaggg aggccgtcga ggccgagctt cagttcgcgc gcgacctgtg
     7141 cggtgacggc ctcccgggga tgaacaccga ctcgatgcgg cagtacctgg agtgcgtggc
     7201 cgaccagcgt ctgacgcggc tcggcttcgc cccggtgtac ggctccgaga accccttctc
     7261 tttcatggag cttcagggtg ttcaggagtt gaccaacttc ttcgagcggc gcccctcggc
     7321 gtaccaggtg gcggtggagg gcaccgtcga cctggacgag gacttctgag gttcctgggt
     7381 cttccgaggc tcctgggttt cctttccctg acccctcccc tcctgggcct ccctgatctg
     7441 gcggtcgatg cgcctgtcgc gcacgatgcc gatcacggag gggaggacca tgaggacgag
     7501 gagtccgaag gtcgcgagca ttccgacaag gccttctatc tggtttccgg tcatgacacc
     7561 actgtcacgc ccaagactcc ttaccggcag tggcaggact gccgtaaggc ctcgatttcc
     7621 tgccaccgac gaggcagact ggcggcatgt tgcagaacgt ggccgccgtc ctgctggacg
     7681 gagcgcaccc cttcgaactc ggcgtgatct gcgaggtctt cggcatcgac cggagcgacg
     7741 agggcctgcc ggggtacgac ttcgcggtgg tctccgcgga ggggccgcgg ctgagcaccc
     7801 acgtcggcgg gctgaccgtc tccacgccgt acggtctgga acggctggag gaggccgacc
     7861 tcatcgcggt gccggccggc tccgacttcg tccgccggga gtacccgccc gagctgctgg
     7921 aagctctgcg ccgggcgacg gcccggggca cccgcgtgct gagcgtgtgc tccggcgtct
     7981 tcgtgctggg cgccgccggg ctgctggacg ggcggcggtg cgcggtgcac tggcaccacg
     8041 cggccgagct ggcccgtcag cacccgcggg cccgggtcga gccggacgtg ctctacgtcg
     8101 acgaggaccc ggtgatcacc tcggccggga cggccgccgg catcgacgcc tgcctgcaca
     8161 tcgtgcgcaa ggagcagggg ccggaggtcg ccaaccggat cgcccggcgc atggtggtgc
     8221 cgccacaccg ggacggcggg caggcgcagt acatcgaacg gccgctgccg cgctcctcgt
     8281 gcgacaccgt cggcgaggtg ctggcctgga tggagcagca cctcgacgag gaggtcacgg
     8341 tcgagcagct ggcggtccgg gcgcacatgt ccccgcgcac cttcgcccgc cgcttccagc
     8401 aggagacggg gacgaccccg taccgctgga tcctgcgcca gcgcgtactg ctggcccagc
     8461 ggctgctgga agcgacggac gagacgatgg actcgatcgc ctggcgcgcc ggcttcggca
     8521 cggcggcggc cctgaggcac cagttcacca gggccctggg gaccaccccg cacgcctacc
     8581 ggcgcacctt ccggggcccg gaggccgccg cctgagccgt cgggtcgtca ccgtgccacg
     8641 ggcctgacca gcagatcgtg cgggcgcagc gtgatgccga cccggaccgc gtcgttggag
     8701 cccgccacct gctcgaagcg gtacttcgtg gcgagcgcgg ccgtgatcag cgtcagctgc
     8761 gccatggaga agtggtcgct ggggcacttc cgcttgcccg cactgaatgg cttcatggcg
     8821 tatttcggca cattcttcgc gcgttccggg agccaccggt cggggtcgaa ctccaggttg
     8881 tcgtcgtacg acttcggatc gcgctggatt gcgtacggac tgtagatgat gtccgcaccg
     8941 gccggaatgc gatagccacc gagttcgctc tcggccaccg cgcgccgcgt caatacccat
     9001 acggccggac gcaaacgcat cgcctccacg acgacattgc cggtgtgcgt gagcccgcgg
     9061 acgtcctcga atgccacggg ccgtccgccg gtgaccgctt cgacttcgtc gcgtatgcgg
     9121 tcggcatgtt ccggatggtc ggcaagtgcc tggagcaacc acatgatcgt ggacgcgatg
     9181 gtttcactgc cgggggtgag tatcgcgacc acctggtcgt ggatctcctg ttccccgatc
     9241 gggtcgccat tgtcgtcctt cgcctccagc aatgccgtga gcaaatcgtc cggcttttga
     9301 ccggatgcgc ggcgctcggc gatgatctcg tcgaccagca gatgcagatc ggccaacgcg
     9361 tcgttgaatc ggcggttggc cggaagcggc aaccggtaca gcggcccgag cgggaccacc
     9421 atccgccggt acatgccccg gaagacggtg gcgagcgcga cgcacagccg ctcggcccgc
     9481 tcgtccatgt actgcccgcg cagcaggcag cgggccgcga cgcgcacggc gacccggaag
     9541 gactcggagg tggcgtcgac ggtctcgccc ggctgccagc gctcggtgag cgcgtgcgcc
     9601 tcctcctcca tgatcggccc gtaggcgggg atggcgtcca gccggaacgc cggctggatg
     9661 gtgcgccgct ggcgccggtg gagcgggccg ttggcggtcg ccacgccctc cttgccgagc
     9721 aggccctcca gtgactccca cagcggtccc gctatgtggt agtcggggtt cagggcaagg
     9781 gcgccggtca gctccgggtt ggtgaccgcg tagacggtct tggggccgag cttgatgcgc
     9841 acgatgtcgc cgtggtcgcg cagctgcgac atgaaggcca gcgggtcgcg ggccagccgc
     9901 cagccgtggc cgagcagcgg tacgccgccg cccgcgacgg gcggtacgcg cagctcccgg
     9961 gccggctgcg cccgggtctc ggggttgacg gactcgacgg tcatttctca cctgccgctt
    10021 cgttgttgac gtacgggggc gtcgaccggt cgtcccagct gtcgaccatg taacggccgg
    10081 actcgtggtg gaaccagtag acggaactga accagttccg catattgccg acgttggccc
    10141 gtacggcgcc gcccagttct tttccgcgta cggtcccgtc ggcgagttcg tcggcgaacc
    10201 gtaaggcgtc ctgctccacg gcgaggaatt cggtgatgca ttcctcgacg cgtcgcctga
    10261 cttctccgat ggcttcttcc agcgtgagtg aatggtgggt gatgagactg attccgagat
    10321 tgtggacctc gtcgcccgct atttccttcg gcagcgagca gaggtcgttg taccaggcgg
    10381 cgaattcctg actcagcagc gccgcccggc gatatgccgg gtgtttccgt acggcgtcgg
    10441 ggagttcgca gcccgaagcc ggctccagca ggtcggtcca gatccagtgc gcgaaggtga
    10501 gccggcgcag ctggaggtac tcctccacgc cgggcacgat tccgcgcgtg cggttgtgga
    10561 attcacggtc gtacgcctcg atcaccgcgt ggaagtgccg ggcgaaccgg gcgttccagg
    10621 tgcccggcag gaaggcgtag agccgccgca cactgtcggc gaacccggcc accagcgtgt
    10681 cctcgtggtg caggtggtcc ccgggtgagt ccagtgccgt gtgcagccgg ccgcgcagcc
    10741 gccgccaggc gccgggacgg ccgtggacga tgtcgcggtc gtggcggtcg tcccagacga
    10801 agaaccacgc gctgtagtcc gctatcgcct gcatgacctc gtcgggggcg cccaggtagt
    10861 agcccgccat gaggtccgtg tagcacaggc cgtcggcata ttccgcgacc ttgtccgccg
    10921 gcatgagccg cttttcgagc agccaggtgc gggtggtctc ctggagcctg ggccaatacg
    10981 ggtgcagttg ccggggaaat gccgcctcga tcaccgggag acggagcgat ggcggtactg
    11041 cgatcgcggt cggtgtcgct gtggtgccgt gtgagaaagc atgcacgaac aaacccctct
    11101 cagccgccgg tggcgcaccc ctctcgctga gcggggcgtg cgccgttgcg tatccccgca
    11161 cttcccattc agcaccacaa ctgaccgttc tgggaacgga tttgctccat tcactacccc
    11221 tcgatgccgg aattctcctg ttgtgtggcg gctttccatg gatgaacacc gacgcgcaca
    11281 gacgcacggc gcccgctcgg ggaagacccg aacgggcgcc gtgcgcaagg gagatgtgtg
    11341 accggtgggg cggtgtcagt cgttcgcgac cacggggtag cgcggctcgt tctcggccat
    11401 ctgccgcagc gcgtccttgc gttcgcgctt ggagagccgg tcgatgtaca ggtacccgta
    11461 caggtggtcc gtctcgtgct gcaaacaccg tgcgaagtac ccggtgccgc gcaccttgac
    11521 cgggttgccc ttctcgtcct gcccggtcac ctcggcgtag tcggggcggg cgagcggcgc
    11581 gtaggcggtc ggcacggata ggcagccctc gttgctgtcg tccaggcggc ggcggtcggc
    11641 cggcagctcg accagcttgg ggttgcagac gacgccgacg tggcggacac cctcgtcgtc
    11701 ggggcagtcg tagacgaaga ccttcttgga gacgccgatc tggttggcgg ccaggcccac
    11761 gccctcggcg gtgcgctggc tggcgaacat gtcggccacc agctgctgga actcctcgcc
    11821 gaagtcggtg acgtcctcgc actccttgtg cagcaccggg ttgccgacca ccgtgatcgg
    11881 gcgcgaggtg ccgcgcccgc gccagtcggc ctcacgctcc tcgcagtcct gggtgtcgac
    11941 gacgaaaccc tcgtcgtcca cggggagcac gcccgggtgc tgctgatcgg tgtcctgctg
    12001 ggccatgacc gacgtatgcc ttcctcgtac aaccaagggt gatgcttgat ggcgactgct
    12061 gctggagcgt cctgacaaag actacggggc cgctcagcag acctcttcca ggtcccgcca
    12121 gtcacgcgag tccggactgt cggccaccca cccgtccagc aaccccttca ccagcccggc
    12181 cggcgcggcc accccgcact cccgctccgg cacccacagc tgcccgtcgg tgcggtgtcc
    12241 caggggcccg gggtgtccgg gttcgctgtg gtcgtgcggg tcgaggtgct cgccctcgcc
    12301 ctcgtcggac ggcatccggg actccgagca catccggcac agcagccgca cggaggacga
    12361 ccagtcctcg gcggcgaacc cggcgtcgga ggccagctgc tccagggcgt cccggtcggc
    12421 ctcggtggcg gcctccagga ggaccaccca ggtgggcacg ggcgacggcg cccacagctc
    12481 gatctcgtcg aagacggggt aggagtgccc ggcgctggtc gtccgctccc cgtgcggcac
    12541 accgtcgtgc aggacgacct cgccccagcg ccgcccggac gacggcagcg ggatggacag
    12601 cacctcgacg cgggcggggt cgagccgccg cccccacacc acctcggcct cgccctcggg
    12661 ggacagccgt acggccgcgc tgccgaggtc catgccgagc ggctcaccgg cgtccgtggc
    12721 gtcccccggg gtgcgcagcc cgtaggcctg ccaggcccgg cgggccagcg gccagtcctg
    12781 gagggcggtg gcggcgatgc cgacgttcca ccagtcgggg gctccggtgt cccggtcgag
    12841 gagcgcgacg gctcggagtc cggccgcccg ggcctgctcc cagtcgtgcc ggaacttgtg
    12901 cagcagggcc aggttgaacc aggactccga cagccagggc tccagatcgg ccgcccgggt
    12961 cagcagcgcg cccgcgtcct cgtagcgacc gtcgccgatc agcgtgaacg cgcggtcggt
    13021 ggcctgccgc caggaggcgg agggccggtg ccgtgccttg ccgaagatcc tcacgattcc
    13081 cgcctgccag ttccgttcag tgggctggct gtgcctttcg cgcccccgga caccctctcc
    13141 tgggcatcaa accacgtacg gctgtagagg cgctcattac ccatgggtta cccagccgcg
    13201 ggcccggtaa ggctgccccg ggcaaggact cgggccagtg cttccaccac ctcgggagcg
    13261 tagtcgctgg cggtggccag gcgcagctcc tccagcgccg tcaggacgcc gcccgggccc
    13321 gcgtcccgcg ccttctcctc gtaggcgttc acgacgcgca cgatccgcgc ggcgaccggc
    13381 tgctcgcggc aggggtccgc ctggcgctcc accaccaccg cgaccgccgc gtcgaccccg
    13441 gtctggcgga cgacggctcc gccgagcagc gcgatccgcc gctgctccgt gacgggcagg
    13501 ccggcggtgg ctcccgccgg gaccgggtcg accaggctga gctggccgat gtcgtgcatc
    13561 agggccgcgt actccagcac ggtcagctcc gccccggaca gccccaggtc ccgtccgacg
    13621 gccaccccga gtccggcgac acggcgggcg tgcccggccg gggtgtaccc ggcgatctcg
    13681 gtggcgcggg ccagggaggc gatggtctgc cggtaggtgg cccggacggc cgcgtaccgg
    13741 cggtaggaca gctgggcgag cagcaggggc acgcagaaga cggggagcgc ccacaggccc
    13801 gcgacgctca ccgcgagcgc catcaccgcg ccggtcgcgc acaccgccga ggtgatgccg
    13861 accatgccgc gcagttcctc gcgcagcagc ggtccgaagg gccagccggt gcgcgcgtgc
    13921 gcgggggcgg cggcgagcac ggcgtcgcac aggctggtca gggcgagcag cgccagcagg
    13981 agcagcgcgt gggcgggacc gctccagtcg tcgaaaacgc cctgctgggc cagcggccgg
    14041 aagcacacgg cggcgaagcc gacggtcagc acgcgccggg ccaggtggtc gaggacgggt
    14101 ccgctgccgc gggcgacgta gggcacgctg ccgagcagcg aggcggcgag cacgacggtg
    14161 acggtctggg cgacaccgtg ctgcgcgggc tgcccggcga cgtctccgag cagcgcgtac
    14221 gccagcgccc ccgcggctcc gagcggtgcg gcctcccggg cctcggcgcc ggtgcgccgg
    14281 gtcagctcac cgaggacgac caggccgccg aaggccagcg ccacgggccg ctgcaccggc
    14341 cccgacccca gcacggaggc gagacacccg agcgcgagga tcccggcgca gccgggtacg
    14401 aggagcgggg ccgccgacgg cgggggctgg gccggtggtg gcgagggcgt catggcgcgc
    14461 ccctgccgac actgtcccgg gcgccctcgc cgcggcccgg ggacggggcg gcggggagcg
    14521 cgggagtgcc gtccgccgtc accgacgggc gccagccgtg gcggccgagg gcgtggacca
    14581 gcgcccgcac catccgcggg tcgaactgcc cgccggcaca ccgctggagc tcctccaggg
    14641 ccgccgcgac ggggcgggcc ctgcggtagg agcgggtgga cgtcatcgcg tcgaaggcgt
    14701 cggcgacggc caccacccgg gccgactcgg ggatccggtc gccggccagt ccgtaggggt
    14761 agccgctgcc gtccagccgt tcgtggtggt gcaggacggc ggcgcgggcc tccccgagga
    14821 agcggatgcc gcgcaccatc tcgtgcccgt actcggggtg cagttcgatc acccggcgct
    14881 cctcgggcgt cagcggcccg tccttgcgca gcagccgggt gggcacgccg agcttgccca
    14941 cgtcgtggag gatccccgcg aagcgcaggg tctcgacgcg ttcgtcgtcc atgcccagct
    15001 cgcgggcgat catcatggag gcctggccga cgcgttcact gtggccgcgg gtgtagccat
    15061 ccttgatgtc gacggcctgc accagggcgc ggatggtcgc ctggtgcgcg gcccgctcgc
    15121 ggtggtactg ggcgaaggcc caccacgcca cgcacatcgg cagcagcacg agcagcgcgg
    15181 ccaccggacc gtacgggctg cgccacagga ccgccatcat cagcccggcg agcccgtgca
    15241 cggcgatcgg cgcgagcgac cgggagagca gcccccgcca ggcccggctc ggcggcacgt
    15301 ggtcggcgag ggcgcggatg ccgccgtcca gcaccgtgag caccaggcag aaggcgagca
    15361 ccgcggcgcc ggccggcacg agggcgtacg ggaaggcggg ctcgaccacc gcgtcccggc
    15421 cgccgagccg ccagtggaca ccggcggcgg cccacacggc gagggtcagc tgggcggccc
    15481 gccacaggcg ccgcaggccg aaggggcgtc gcggcaccgg ggacagcagc gcccccggca
    15541 gggccacgag cgcggcggcg ggcggcggca gcaggaaggc accggcgagc agaacgggat
    15601 agcaggtccc gacgaagcgg gaccgcgcga cgagttcgga acccgcgtac agtccggcga
    15661 gcagcagcac cgcccaccag ggcgcgtgca ccgacggcag cggccacagg cagagcagtg
    15721 cggcgagggc gacgccggtc acgtagaccc gtgcccgcgc cggtaccgcg tccatgagcc
    15781 cctcccccgg ccacgtctgt caggctccgg agcctaggac ggcgggggga ggccgcgggc
    15841 agataacccg cggattagca cgtacgagtg acttctgacg gcgtcaggac actcaggccg
    15901 gctcaggact cctgcggagc cgacgacggc gcggccgtca cgtcgtgttc cggcacggac
    15961 tgcccggacc ggatcaggtc cagccgtccc atgaccttgg cgcgcaggtc acccggtacg
    16021 tcgtcctgtc cgcagcaccg cttgaccagc ttcttcacgg cctgctccag cccgtacttc
    16081 tccaggcagg gcgagcattc ctcgaagtgg tgctcgaact tcacgcagtc cgagtccggc
    16141 atctccttgt cgagaaactc gtagagatga tcgaggattt cgctgcaatc cgtctcgtgc
    16201 ggctctccgc agctcatgac cccgagcctt tcgcttcgtt cgactctccg gcgccggcgg
    16261 ggaccaggcc gcggtcgcgg gcgtagtcct ccagcatgcc gcgcagctga cggcgtccac
    16321 ggtgcagccg ggacatcacc gttccgatgg gtgtccccat gatgtctgcg atctccttgt
    16381 aggcaaagcc ctcgacgtcc gccaaataca cggcgatacg gaactcctcg gggatcgcct
    16441 ggagcgcctg cttcacgtcc gaatcgggca ggtggtcgag cgcctgcgac tccgcggagc
    16501 gcagacccgt cgacatgtgc gactcggcac gcgcgagctg ccagtcctcg atctcctcgg
    16561 ccgcgctgcg ctggggttcg cgctgcttct tgcggtacga gttgatgaag gtgttggtga
    16621 ggatgcggta cagccacgcc ttgaggttgg tgccctcgcg gaactggtgg aaggacgcgt
    16681 acgccttggc gtaggtctcc tgcaccaggt cctcggcgtc ggccggatta cgcgtcatgc
    16741 gcagcgcggc cgagtacatc tggtcgagga actccagcgc gtcccgttcg aagcgcgcgc
    16801 tgcgctccgc ggtcgactcc gcgtccgtac cccggccctc gggctgctcc gcctggccgt
    16861 gttcggtccc tgcgtcggtc ccagtgaccg gacccacctc ctccagtgac gtcgtgaaac
    16921 cgaatgcggt ctcactcgaa tcggaggata gacgacctgc ggtcggggac gcttgccgat
    16981 ccggtccgcc cgccgaccga atgggggcgg tcttcgccgc gtgcagcacc gtccagtcca
    17041 gatcggaccg gctgctgcgg ctcgggcaga aggctgaacc catgcggcgg acttcctctc
    17101 ctacggcgtc ggtgctgatt ctcagcaacg tatgcaccgc acaacagcgg ccgtccgccg
    17161 gtcattcccg ggcgttcagc cgagtgagcc ggtccacttc aggacgccgt cggtgatcag
    17221 ctccagcgcc tcctcctggc cgatctccgc ccgcttgggc acggcgaagc cgtggtcgcc
    17281 gtacggcacc tcgatcagct cgtaggttcc cgcgggcgcc tcggggaact cccgcggtct
    17341 gccgaagggg tcgttgccgc cctggacgac gagggtgggc accccggacc ccagcagctc
    17401 ttcggcacgc gacttctccg gcttgcccgg cgggtgcagc gggaagctca gggcgaggac
    17461 ggcacgggcg cccagttcgg cggcggtacg gcaggcgacg cgggcgccgg cgctgcggcc
    17521 gcccgagacc accggcaggc cgggcgcggt gagcgcgggc cagacgcccc gccagccggt
    17581 gtcgagggtc ttcggcgcgg gcgccagctt cttgccggcc acccgccagg gctgctcgac
    17641 gagggcgaca ctcaccccgt gggcgggcag ggcggccgcc agcgccttca ggtcgcgcgc
    17701 ctcgatgccg ccgccggcgc cgtggctcgc ggcgaggacg agccggggcc gctccgccgg
    17761 gtgccaggtg atgcgggcgg gacccgcatc cgtctcgacc gtctctgtca caacctctgt
    17821 cgcatccgtc acgtcagaag agtgtgccct cttccggccc ctccagctcc ttgagcagct
    17881 ccggcccgtt gttgcggacg ttgctcacgg tcgtcgagac gggataggcc cgcagcagtc
    17941 cggcgggcgg cggcgccagc agcgaggtca gctcgtcggg gtcggtgcgc gccgggtcga
    18001 gccaggcgtc ccagcggtcc ggcgtcagca tcagcggcat ccgcgggtgg atgtcggcca
    18061 gcgcgtgcgg gccgtcggcc ggggcgacgg cgagcggcgt ggtctcggcc tcggtggtga
    18121 tcaccgagca cgtcacccac caggcctgcg ggtggtcgtc gggcagggtc ttgtcccgcc
    18181 agaactcgta gagcccggcc atggcgaaca cggagccgtc ggcgggggtg acgaagtacg
    18241 gctgcttgcg cggccgcttc ttgcgcccct cgacctccag gtcccgctcc tgcttgccgg
    18301 tgacccactc gtagtagccg tcggcgggca ggatgcagcg ccgggtgctg aaggcgcggc
    18361 ggtaggaggg cttctcgtgg acggtctccg cgcgggcgtt gatcatccgg gcggcgccct
    18421 cggacgtctt ggaccaggag gggacgaggc cccacttcag tttccgcagc tggcgaaccg
    18481 gcttcgggtc ctcgacgtct ttcagggggc ggtccaggac tgcgtggacc tccttggtgg
    18541 gagccacgtt gtagtcggga tccaagctct ccttgggctc ccacttctcg atctcgaaga
    18601 ttcccgcgag atcctcgggt cgacgactcg ccgcataccg tccgcacata cgtgccacac
    18661 tgccaggccc gcccgtctcc cgaccaccac ccctcaacga ggcgctgcgc gccacacccg
    18721 cacgtccgct agtacgagga gccctccccg aacatggacc acctcgcgac ggcctcgctc
    18781 acctccctgt gggacgaggt ctccggcacc cagcccgatc ccgacctgtg ggtggtgatc
    18841 gcgaccctgg tggcggcgct cgccgtcgtc gtgacacgcg ggtcgtggcg gatagcgcgc
    18901 aacgcgatca ccatcgccca cgagggcggc cacgggctgg tggccctgct gaccgggcgg
    18961 accctgaccg ggatcaccct gcactcggac accagcggtc tgacggtgag ccggggcaag
    19021 ccgcacggca tcggcatgat cctcaccgcg gtcgccgggt acaccgctcc cccgctgctc
    19081 ggcctcggcg gcgccgcgct gctggcggcg gggcgcatca ccctgctgct ctggctggcg
    19141 acggcgctgc tcgtggccct gctggtgatg gtccgcaacg cctacggggt gctgacggtg
    19201 gtggtcaccg gcggcacgtt cgtcctggtg tcctggctgg ccggaccgca ggtgcaggcg
    19261 gcgttcgcgt acgcggtggt gtggttcctg ctgctcggcg gggtgcgccc ggccttcgag
    19321 ttgcaggcca agcggtcgcg gggcggcgcc ggggactcgg acgcggacca gttggcgcgg
    19381 ctgacgcacg cgcccgcggg ggtgtggttc ttcctgttcc acgcggtgtc gctgtgctcg
    19441 ctgatcggcg gcgggcgctg gctgctggag ctgtgaggcc tcgggggccg tctgcctgct
    19501 gcgcatatat gcacggcaag tgcactgttg cgttttcggt caggtttcgc cgcttttgat
    19561 caagatctcc gatcgtcctc agccattaaa gtggggccca tgaccgtgaa ccccgcgcac
    19621 accaccctct ggcccgcccc gcacgcgagc ggggccgtcg acgcgaccgt ccacgtgccc
    19681 gggtccaagt cggtcaccaa ccgtgccctg gtgctggccg cgctcgcctc cgagcccggc
    19741 tggctgcgcc gcccgctgcg ctcccgcgac accctgctga tggccgaggc cctgcgcacg
    19801 atgggcgtcg agatcgagga gggcgtcggc cccgagggca ccggcgagtt ctggcgggtc
    19861 atcccggccg gcctgcgcgg cccggccacg gtcgacgtcg gcaacgcggg cacggtcatg
    19921 cgcttcctcc cgccggtcgc cacgctggcc gacggcaccg tccgcttcga cggcgacccg
    19981 cggtcgtacg agcgtccgct gcacggtgtg atcgacgcgc tgcgcgccct gggcgcccgc
    20041 atcgacgacg acgcgcgggg cgcgctgccg atgaccgtgc acggcggcgg cgccctggag
    20101 ggcggtccgg tcgagatcga cgcgtcgtcc tcctcccagt tcgtcagcgc cctgctgctg
    20161 tccggaccgc gcttcaacca gggcgtcgag gtgcgccaca ccggctccgc gctgccctcc
    20221 atgccgcaca tccgcatgac ggtcgacatg ctgcgcgcgg tcggtgccca ggtcgacacc
    20281 ccggagtccg gcggcgagcc gaacgtctgg cgggtcaccc cgggcgcgct gctcggccgg
    20341 gacctgacga tcgagccgga cctgtcgaac gcccagccgt tcctggcggc ggcgctggtg
    20401 accggcggca gggtggtgat ccccgactgg ccgtcccgca ccacccagcc cggtgaccgg
    20461 ctgcgcgaga tcttcaccga aatgggcggt tcctgcgaac tgaccgacta cggtctcgtc
    20521 ttcaccggat cgggtgccgt ccggggcatc gacgtcgacc tcggcgaggt cggcgagctg
    20581 accccgggca tcgcggccgt cgccgccctc gcggactccc cttcgaccct gcgcggcgtg
    20641 gcccacctgc ggctgcacga gacggaccgg ctggccgcgc tcaccaagga gatcaacgaa
    20701 ctcggcggtg acgtcaccga gaccgccgac ggtctgcaca tccgcccgcg ccggctgcac
    20761 ggcggcgtct tccacaccta tgaggaccac cgcatggcca ccgccggcgc gatcatcggc
    20821 ctcgcggtcg agggcgtcca gatcgagaac gtggcgacga ccgccaagac gctgcccgac
    20881 ttccccgacc tgtggaccgg gatgctcggg gcgtagggac ggttcgccat gcgccgctac
    20941 ggcaagcaca ccgacgagga cgacatccgc tcgcgcccca accgcaaggg caaccggccg
    21001 cgcacccaca tccggcccaa gcacgaggac gccgccgagg gcctggtcct caccgtggac
    21061 cgcggcaggc tgacctgcct ggtgga
//
