LOCUS       NZ_KZ195574            21158 bp    DNA     linear   CON 06-SEP-2024
DEFINITION  Streptomyces sp. CS113 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ195574
VERSION     NZ_KZ195574.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS113
  ORGANISM  Streptomyces sp. CS113
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8695358)
  AUTHORS   Malmierca,M.G., Gonzalez-Montes,L., Perez-Victoria,I., Sialer,C.,
            Brana,A.F., Garcia Salcedo,R., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Searching for Glycosylated Natural Products in Actinomycetes and
            Identification of Novel Macrolactams and Angucyclines
  JOURNAL   Front Microbiol 9, 39 (2018)
   PUBMED   29441046
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8695358)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Searching for glycosylated natural products in actinomycetes
            isolated from leaf-cutting ants: activation of two silent clusters
            and identification of a novel macrolactam
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8695358)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAY-2017) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 78.17x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002188365.1-RS_2024_09_06
            Annotation Date                   :: 09/06/2024 02:31:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,790
            CDSs (total)                      :: 7,719
            Genes (coding)                    :: 7,614
            CDSs (with protein)               :: 7,614
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 1 (5S, 16S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 105
            CDSs (without protein)            :: 105
            Pseudo Genes (ambiguous residues) :: 0 of 105
            Pseudo Genes (frameshifted)       :: 35 of 105
            Pseudo Genes (incomplete)         :: 81 of 105
            Pseudo Genes (internal stop)      :: 4 of 105
            Pseudo Genes (multiple problems)  :: 15 of 105
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:56:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2956836
            Orig. end                         :: 2977994
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ195574.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Salas's laboratory, A.
            Microbiology, University of Oviedo, Spain.
FEATURES             Location/Qualifiers
     region          1..21158
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="19"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21158
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21158
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11158](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11158)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(82..1047)
                     /locus_tag="B9W62_RS12665"
                     /old_locus_tag="B9W62_12705"
     CDS             complement(82..1047)
                     /NRPS_PKS="Domain: PKS_ER (20-318). E-value: 9.3e-34.
                     Score: 108.9. Matches aSDomain:
                     nrpspksdomains_B9W62_RS12665_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571395.1"
                     /locus_tag="B9W62_RS12665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12705"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_087807278.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.9e-20, bitscore:
                     70.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFAVYAARIDRDQPLAGLELGELPAPEARPGWSVVDVRAASLNHH
                     DLWSLRGVGLPEDRLPMILGCDAAGIDADGNEVVLHSVIGQTGHGVGPKEPRSILTERY
                     PGTFAEQVAVPTWNILPKPKELSFEEAACLPTAWLTAYRMLFTNAGVRPGDSVLVQGAG
                     GGVATAAIVLGKAAGLRVFATSRDEAKRKRALELGAVEAVETGARLPQRVDAVIETVGA
                     ATWSHSIKSLRPGGTLVISGATSGDRPSHAELTRIFFLELKVVGSTMGSKDELEDLLSF
                     CAATGVRPVIDEVLPMDRAREGFERMASGGQFGKIVLSNS"
     aSDomain        complement(94..987)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9W62_RS12665_PKS_ER.1"
                     /evalue="9.30E-34"
                     /label="B9W62_RS12665_PKS_ER.1"
                     /locus_tag="B9W62_RS12665"
                     /protein_end="318"
                     /protein_start="20"
                     /score="108.9"
                     /tool="antismash"
                     /translation="GELPAPEARPGWSVVDVRAASLNHHDLWSLRGVGLPEDRLPMILG
                     CDAAGIDADGNEVVLHSVIGQTGHGVGPKEPRSILTERYPGTFAEQVAVPTWNILPKPK
                     ELSFEEAACLPTAWLTAYRMLFTNAGVRPGDSVLVQGAGGGVATAAIVLGKAAGLRVFA
                     TSRDEAKRKRALELGAVEAVETGARLPQRVDAVIETVGAATWSHSIKSLRPGGTLVISG
                     ATSGDRPSHAELTRIFFLELKVVGSTMGSKDELEDLLSFCAATGVRPVIDEVLPMDRAR
                     EGFERMASGGQFGKIVL"
     CDS_motif       complement(535..588)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9W62_RS12665_0002"
                     /evalue="6.00E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="B9W62_RS12665"
                     /protein_end="171"
                     /protein_start="153"
                     /score="15.7"
                     /tool="antismash"
                     /translation="GDSVLVQGAGGGVATAAI"
     CDS_motif       complement(619..657)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9W62_RS12665_0001"
                     /evalue="5.60E-04"
                     /label="PKSI-ER_m4"
                     /locus_tag="B9W62_RS12665"
                     /protein_end="143"
                     /protein_start="130"
                     /score="13.4"
                     /tool="antismash"
                     /translation="AACLPTAWLTAYR"
     gene            complement(1317..2546)
                     /locus_tag="B9W62_RS12675"
                     /old_locus_tag="B9W62_12710"
     CDS             complement(1317..2546)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997977.1"
                     /locus_tag="B9W62_RS12675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12710"
                     /product="NADP-dependent malic enzyme"
                     /protein_id="WP_087807280.1"
                     /transl_table=11
                     /translation="MAAEIVNPRSDSEAGAEQKEGAEPLDAFDPAFALHRGGKMAVQAT
                     VPIRDKDDLSLAYTPGVAKVCSAIAEQPDLVHDYTWKSSVVAVVTDGTAVLGLGDIGPE
                     ASLPVMEGKAILFKQFGGVDAVPIALNCTDADEIVETVVRLAPSFGGVNLEDISAPRCF
                     EIERKLQERLDIPVFHDDQHGTAVVTLAALRNAARLSGRTLGELRAVISGAGAAGVAIA
                     KMLVEAGIGDVAVADRKGVVSADRDDLTPVKQELASFTNKAGLSGPLEAALAGADVFIG
                     VSGGTVPEPAVASMAEGAFVFAMANPNPEVHPEVAHKYAAVVATGRSDFPNQINNVLAF
                     PGIFAGALQVRASRITEGMKLAAAEALASVVGDDLAADYVIPSPFDERVAPAVTAAVAA
                     AARAEGVARR"
     misc_feature    2575..2590
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.76"
                     /tool="antismash"
     misc_feature    2626..2641
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.47"
                     /tool="antismash"
     misc_feature    3070..3085
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.94"
                     /tool="antismash"
     gene            3183..4145
                     /locus_tag="B9W62_RS12685"
                     /old_locus_tag="B9W62_12715"
     CDS             3183..4145
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973710.1"
                     /locus_tag="B9W62_RS12685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12715"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_087807282.1"
                     /transl_table=11
                     /translation="MTARFTRRTTAAHSRLAAVGAIAVAGALLLTGCGDQTENGDSSGS
                     DNQSAAGAPLADKLPQSIRDKGTIKVGSDIAYAPVEFKDDSGKTVGIDPDLADALGKQL
                     GVKFEFENGTFDTLITGLRSKRYDIAMSAMTDTKDRQEGIDSDTGKKVGQGVDFVDYFT
                     AGVSIYTKKGDNQGIKTWSDLCGKKLVLQRGTVSEDLAKAENEKCPAGKKISMEAFDND
                     QQAQTRLRAGGADAGSSDFPVAAYAVKTSGGGKDFELVGEQVEAAPYGIAVAKDNAQLR
                     DALKAALDAVIANGEYKKIMDKWGVAEGAVTEAAVNGGK"
     gene            4176..5126
                     /locus_tag="B9W62_RS12690"
                     /old_locus_tag="B9W62_12720"
     CDS             4176..5126
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973711.1"
                     /locus_tag="B9W62_RS12690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12720"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_087807283.1"
                     /transl_table=11
                     /translation="MTVDIDKTAGGPAGNPPTPPEAIKAIPVRHYGRYVSAVVAIALLA
                     AVVYAFSQGKINWGAIPDYFFDDRVLTGMGKTLLITVLAMLIGIVGGILLAVMRLSKNP
                     VTSSIAWFYIWFFRGTPVLVQLVVWFNLGLVFEYINLGPFYRDEWSDFMTPFLTALLGL
                     GLNEAAYMAEICRAGLLAVDEGQTEAAHALGMSHSRTLRRIVVPQAMRVIVPPTGNEVI
                     NMLKTTSLVSVVQYAELFRVAQDIGQTSGAPAEMLFLAAAWYLLLTSVFSVGQYYLERY
                     YARGSSRSLPPTPMQKIRANLFSLSNRSSTTGGAA"
     gene            5123..5884
                     /locus_tag="B9W62_RS12695"
                     /old_locus_tag="B9W62_12725"
     CDS             5123..5884
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973712.1"
                     /locus_tag="B9W62_RS12695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12725"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_087807284.1"
                     /transl_table=11
                     /translation="MTAMVKAEGVHKSFGAVEVLKGIDLEVEQGEVFCLIGPSGSGKST
                     FLRCINHLEKINAGRLYVDGELVGYRQKGDRLYELKDSEVARKRRDIGMVFQRFNLFPH
                     MTAVENVMEAPVQVKGMSRPQARERARALLERVGLGDKAGNYPSQLSGGQQQRVAIARA
                     LAMDPKLMLFDEPTSALDPELVGDVLDVMRDLAESGMTMVVVTHEMGFAREVGDSLVFM
                     DDGVVVESGNPRDVLTDPQHDRTKAFLSKVL"
     gene            complement(5946..6758)
                     /locus_tag="B9W62_RS12700"
                     /old_locus_tag="B9W62_12730"
     CDS             complement(5946..6758)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983528.1"
                     /locus_tag="B9W62_RS12700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12730"
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="WP_087807285.1"
                     /transl_table=11
                     /translation="MTNADTTTTTTTATPAATPATAAGADWQAWQQSWDRQQEWYMPDR
                     EERFRIMLDMVEALVGTAPRVLDLACGTGTITARLLDRFPQATSTGVDLDPALLAIAEG
                     TFAGDERVSFVTADLKDPDWPSKLPYGSYDAVLTATALHWLHADPLADLYGRVADLVRD
                     GGVFMNADHMIDDTTPRINAAERAQRHARMDAAKEQGALDWAEWWQLAAKDPVLAGPTA
                     RRFEIYGEHADGDMPSAAWHARVLREKGFGEARPVWCSPSDTLLLAVK"
     gene            6857..7486
                     /locus_tag="B9W62_RS12705"
                     /old_locus_tag="B9W62_12735"
     CDS             6857..7486
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326935.1"
                     /locus_tag="B9W62_RS12705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12735"
                     /product="ABATE domain-containing protein"
                     /protein_id="WP_087807286.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNTEEPSRGQDSLTSVEAVRDLFGANQSAARR
                     ASDADVTRFRSVRGRLRAVFEAADGGDETLAVDLLNSLLLEFPVSPQISGHDHRAEDGS
                     PLWHMHLADHPSNATAGFAAIAAMGLAFHLTEYGVDRLGLCEAAPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLEADRSASTGLTADSTQRTTASGER"
     gene            complement(7390..7827)
                     /gene="sodX"
                     /locus_tag="B9W62_RS12710"
                     /old_locus_tag="B9W62_12740"
     CDS             complement(7390..7827)
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925778.1"
                     /locus_tag="B9W62_RS12710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12740"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_179235464.1"
                     /transl_table=11
                     /translation="MPEQLSQETERARGTLPFGPAEVTGPSMVPTLHHGDVLLVHWGAR
                     VRPGDVVVLRHPFQQDLLVVKRAAERRGTGWWVLGDNAFAGGDSTDYGVVPQDLVLGRV
                     RFRYRPPRPGQRSPLAVVRWVLSAVRPVLADRSASRRLRAR"
     gene            7973..8368
                     /gene="sodN"
                     /locus_tag="B9W62_RS12715"
                     /old_locus_tag="B9W62_12745"
     CDS             7973..8368
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="B9W62_RS12715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12745"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_003973716.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVTVSAHCDLPCGVYDPAQARIEAESVKAVQEKMAGN
                     DDPHFQTRATVIKEQRAELAKHHVSVLWSDYFKPPHFEKYPELHQLVNDTLKALSAAKG
                     SKDPATGQKALDYIAQIDKIFWETKKA"
     gene            complement(8533..9117)
                     /locus_tag="B9W62_RS12720"
                     /old_locus_tag="B9W62_12750"
     CDS             complement(8533..9117)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973718.1"
                     /locus_tag="B9W62_RS12720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12750"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_087807288.1"
                     /transl_table=11
                     /translation="MRKLTYFVACSIDGFIGGPDGDATFMVPFVDEEFFAFLKSEYPET
                     LPTHGRRPLGIDDLPNKRFDTIVQGRASYDLALKEGVTSPYAHLREYVASRTLTESPDP
                     NVEIISTDLVGRVRELKAEDSAFDIYLCGGAAVAGELADEVDELVIKSYPVVLGTGMPM
                     FASGFAVSEFVTDSVRTFGNGVVVRTYHRKR"
     gene            complement(9194..9790)
                     /locus_tag="B9W62_RS12725"
                     /old_locus_tag="B9W62_12755"
     CDS             complement(9194..9790)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444621.1"
                     /locus_tag="B9W62_RS12725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12755"
                     /product="N-acetyltransferase"
                     /protein_id="WP_087807289.1"
                     /transl_table=11
                     /translation="MGVVIRTAGEDDRDLVVRLLDEAFQDDPVSSWVFPGEEYRRRTHH
                     RLMAAFADAVFADGRIDLTEDGAACALWLPVPADEHTAAEDAPAQIREAVDPENERVEL
                     IARLTDGIHPTGRAHEYLWMIGVLPGRQGEGLGTALIESVLDRCDRERLPAYLEASSAR
                     GKALYERLGFEFTGRALDLPDGPRMWPMWREPQTR"
     gene            complement(10001..11158)
                     /locus_tag="B9W62_RS12730"
                     /old_locus_tag="B9W62_12760"
     CDS             complement(10001..11158)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973720.1"
                     /locus_tag="B9W62_RS12730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12760"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_087807290.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.5e-61, bitscore:
                     206.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETRRGGTATRRPTGAPERHGPIGTQREKEPAESSDGPGRAAEG
                     HEAAVLLSESRASVDPELRSAIASLPESMRRIALYHFGWQHADGTPAAGNAGKAIRPAL
                     VLTAATALGGPAARAAAGRAAAAVELVHNFTLLHDDVMDRDATRRHRPTAWTVFGDADA
                     ILAGDALQALALRLLAADPHPASAAAAARLADCVMELCEGQHADTAMERRPPGEVTLDE
                     TLAMAEAKTGALLGCACALGALYAGAATEDVEALDAFGREAGLAFQLIDDVIGIWGDPR
                     HTGKPAGADLAARKKSLPVVAALTSGTTAAAELAELYAAPYDEGKEDLERTALAVERAG
                     GRDWAQAQAADHMAKAMQELARAVPEPEAAGGLLALAEFVTRRST"
     misc_feature    11186..11201
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.47"
                     /tool="antismash"
     misc_feature    complement(11186..11202)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.43"
                     /tool="antismash"
     gene            complement(11244..12650)
                     /locus_tag="B9W62_RS12735"
                     /old_locus_tag="B9W62_12765"
     CDS             complement(11244..12650)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="B9W62_RS12735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12765"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_087807291.1"
                     /transl_table=11
                     /translation="MSVGEEVRTEQTRPQQSLGTAAARNLATTTKSVPQMQEISSRWLL
                     RSLPWIDVQGGTYRVNRRMTFAVGDGRVTFVKTGDRVEVIPAELGELPALRSYEDDEVL
                     SELAQRCEQREFGPGEVIASFGGRADEVYLLAHGKIEKIGTGPYGDDAVLGVLADGAYF
                     GDQALLDGDAIWEFTARTVTACTVLVLPRQEVEQVAERAESLREHLEQRRSIPEQRTNK
                     HGEKEIDLAAGHSGEPDIPHTFVDYEARPREYELSVAQTVLRIHSRVADLYNQPMNQTE
                     QQIRLTVEALKERQEHELINNREFGLLHNCEYDQRIQPHEGVPGPDDLDELLSRRRGTK
                     LLLAHPRAIAAIGRELNKRGLVPETIDVAGNRIPTWRGVPIYPCNKIPVTEARTSSIIA
                     MRTGEQDQGVIGLRATGIPDEIEPSLSVRFMGINEQAVIKYLVTAYYSAAVLVPDALGV
                     LENVEIGRWR"
     misc_feature    complement(12718..12731)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.09"
                     /tool="antismash"
     misc_feature    complement(12812..12826)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.0"
                     /tool="antismash"
     misc_feature    complement(12953..12966)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.81"
                     /tool="antismash"
     gene            12989..13567
                     /locus_tag="B9W62_RS12740"
                     /old_locus_tag="B9W62_12770"
     CDS             12989..13567
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030135.1"
                     /locus_tag="B9W62_RS12740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12770"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_087807292.1"
                     /transl_table=11
                     /translation="MSASSFLKALKAEGLTVVEVGDWRDHNRNHKGPWGPVNGVMIHHT
                     VTRGSARTVEICRKGHESLPGPLCHGVITKDGRVHLVGYGRANHAGLGDDDVLRAVVAE
                     KALPRDNEANTDGNRHFYGFECENLGDGKDPWPAAQLDAIERAAAAVCRHHGWNERSVI
                     GHLEWQPGKVDPRGFTMASMRERIRDRLK"
     gene            13824..14732
                     /locus_tag="B9W62_RS12745"
                     /old_locus_tag="B9W62_12775"
     CDS             13824..14732
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973723.1"
                     /locus_tag="B9W62_RS12745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12775"
                     /product="1-aminocyclopropane-1-carboxylate
                     deaminase/D-cysteine desulfhydrase"
                     /protein_id="WP_087807293.1"
                     /sec_met_domain="PALP (E-value: 6.7e-18, bitscore: 63.9,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGTDTRDLAALRPRLPSPLHEVADGRFERRGVRLLLKRDDLIHP
                     ELVGNKWRKLAPVLAAADGRTVVTFGGAYSNHLRAAAAAGRLLGLSTVGVVRGQELAGR
                     PLNPSLARCAADGMRLHFVDRSTYRRKSEPETLAALLRAVDAEGAVVVPEGGSNTEAVR
                     GCRALGEELGEHADVAALACGTGGTLAGLAAGLPRGRRALGIPVLRGGFLEGDIRRLQE
                     RAFGGPRGTWSLDDRFHHGGYARTTPALDAFAEDFERRHGLPVERVYVAKMLYALLALT
                     EEGAFPRGTALAAVVTGRPFP"
     gene            complement(14799..16391)
                     /locus_tag="B9W62_RS12750"
                     /old_locus_tag="B9W62_12780"
     CDS             complement(14799..16391)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973724.1"
                     /locus_tag="B9W62_RS12750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12780"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_087807294.1"
                     /transl_table=11
                     /translation="MDVMPLLLLVAGSAAIAAAGRRVPVPVPLLLVAAGLAVSYVPGVP
                     DYTLDPHIVLPLLLPPLLYTAATDSSYLDLRAQARPVALLSVGYVLFATFVVGCAAYLI
                     VPGLPLTAALVLGAVVAPPDAVAATAVARRVGLPSRITTILQGESLVNDATAITAFKVA
                     LAAAVGEGATWAGGIGEFLIAAVGGVGVGLVLMVPLHWLRTHLTEALLQNTLSLLIPFV
                     AYAVAEQVHASGVLAVVVVALYLGHRAWEVDFATRLQEEAVWKMVAFVLESAVFALIGL
                     QLPVVLKGLGEYEGIDAAWYALAVFLVVAVARFVWVYPATFLPRLSARVRAREGDLSWK
                     GPFVIGWAGMRGVVSLAIAFSIPLTVHGGEPFPERNLILFLTFTTVIGTLVVQGVSLPP
                     LIRLLKFPAHDVQAETLAEANAQAQASRAAELHLDELLADERNALPAPLADRLRMVLER
                     RRNAVWERLGQVNPVTGETVDDTYRRLSREMISAEREVFVRLRDGRYIDDEMLRTLLRR
                     LDLEEAAAYRETT"
     gene            16453..16713
                     /locus_tag="B9W62_RS12755"
                     /old_locus_tag="B9W62_12785"
     CDS             16453..16713
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571357.1"
                     /locus_tag="B9W62_RS12755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12785"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_087807295.1"
                     /transl_table=11
                     /translation="MKQCTHADALPHPEPEPCGETCPECLAEGTDPVQLRLCLSCGHVG
                     CCDSSPRQHATAHYKETGHPVMRTFEPGESWRWCFVDHVLV"
     misc_feature    complement(16822..16835)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.89"
                     /tool="antismash"
     gene            16964..17377
                     /locus_tag="B9W62_RS12760"
                     /old_locus_tag="B9W62_12790"
     CDS             16964..17377
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="B9W62_RS12760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12790"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_004925829.1"
                     /transl_table=11
                     /translation="MSQIAGEPATQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGHAPSRDTFAWTV
                     LSALAGKVSSAVDEDKTVSISLYKQRGAGPGPA"
     gene            17395..18459
                     /locus_tag="B9W62_RS12765"
                     /old_locus_tag="B9W62_12795"
     CDS             17395..18459
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136656.1"
                     /locus_tag="B9W62_RS12765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12795"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_179235465.1"
                     /transl_table=11
                     /translation="MRDEERGTRELPAEGTRSPNEARRTADGIDGIPEQARPHPEDETS
                     PEAVVPGDGQRTGDTPVRPVRAEAGARERATGGTMSEHERHSEGQAPGARGAQGTRHDP
                     QDRSGARLLFAELRTLTKDSPEYAELRNRLVRMHLPLVEHLARRFRNRGEPLDDLTQVA
                     TIGLIKSVDRFDPDRGVEFSTYATPTVVGEIKRHFRDKGWAVRVPRRLQELRLALTTAT
                     AELSQLHGRSPTVHELAEKLSISEEEVLEGLESANAYSTLSLDVPDTDDESPAVADTLG
                     AEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQEVGISQMHVSRLLA
                     RTLAQLREKLLVEE"
     gene            complement(18508..18981)
                     /locus_tag="B9W62_RS12770"
                     /old_locus_tag="B9W62_12800"
     CDS             complement(18508..18981)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326947.1"
                     /locus_tag="B9W62_RS12770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12800"
                     /product="hypothetical protein"
                     /protein_id="WP_087807297.1"
                     /transl_table=11
                     /translation="MSSEQTPTTPASAAADADARAEAADPRPGRLTAAAALAALEGLAL
                     VVGGAWMLVEGLTGHPDDRTSAVTGGVTLIVLALLPLLAARGLIGRKGWSRGPAVITQI
                     MALPVAYNMVRADSLAVPAGIVLGVVAVTALVLLVNPTTTQALGIRGPGSAEK"
     gene            19109..20077
                     /locus_tag="B9W62_RS12775"
                     /old_locus_tag="B9W62_12805"
     CDS             19109..20077
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127486.1"
                     /locus_tag="B9W62_RS12775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12805"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_087807298.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLEAVTTEYRGHARD
                     LGRQAAQSDDIDLVVALGGDGTVNEVVNGLLHAGPDPEHLPGLAVVPGGSTNVFARALG
                     LPNHAVEATGALLDALREGSERTVGLGLASGTPGSEDEGVPARWFTFNAGLGFDAGVVG
                     RVEQHRERGKKSTHALYVRQVVRQLIGEPHRRSGTITLERAGEDPVTDLVLSIVSNTCP
                     WTFLGNRPIYASPEASFDTALDVFGLSRLSTAAVARYGTQLLTSSPERGPRGRHAVSLH
                     DLTDFTLHSKVPLPLQMDGDHLGLRTSVAFTGVRRALRVIV"
     misc_feature    complement(20162..20176)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.74"
                     /tool="antismash"
     misc_feature    complement(20167..20176)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    complement(20338..20353)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    20341..20352
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            20398..20655
                     /locus_tag="B9W62_RS12780"
                     /old_locus_tag="B9W62_12810"
     CDS             20398..20655
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="B9W62_RS12780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_12810"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_003973730.1"
                     /transl_table=11
                     /translation="MDWRHRAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVMEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQASA"
ORIGIN
        1 tcgcccgacg gccgggaccg gcgcccggca acgcgaacgg cgggcccgga gaaccggacc
       61 cgccgcaggt ggggaaacgc gtcaggagtt gctgagcacg atcttgccga actgcccccc
      121 ggaggccatc cgctcgaacc cctcacgagc ccggtccatc gggagcacct cgtcgatgac
      181 gggccgtaca ccggtggcgg cgcagaagga cagcaggtcc tccagctcgt ccttggagcc
      241 catcgtggag ccgacgacct tgagctccag gaagaagatc cgggtcagct cggcgtggga
      301 gggccggtcg ccgctggtgg caccggagat gaccagcgtg ccgcccggcc tgagcgactt
      361 gatcgagtgc gaccacgtgg cggcgcccac ggtctcgatc acggcgtcca cccgctgcgg
      421 cagccgcgca ccggtctcga cggcctccac cgccccgagc tccagggccc gcttgcgctt
      481 ggcctcgtcc cggctggtgg cgaagacccg cagcccggcc gccttgccga gcacgatcgc
      541 ggccgtggcg accccgccgc cggcgccctg caccagcacc gagtcaccgg gacgcacccc
      601 ggcgttggtg aacagcatcc ggtacgccgt cagccatgcg gtcggcagac aggcggcctc
      661 ctcgaaggag agctccttgg gcttgggcag gatgttccag gtcggcacgg cgacctgctc
      721 ggcgaaggtc cccgggtagc gctcggtgag gatggagcgg ggctccttgg ggccgacacc
      781 gtggccggtc tgtccgatca cggagtgcag gacgacctcg ttgccgtccg cgtcgatccc
      841 ggcggcgtcg cagccgagga tcatcggcag ccggtcctcg gggaggccga cgccgcgcag
      901 ggaccacagg tcgtggtggt tgagggaggc ggccctgaca tcgacgacac tccagcccgg
      961 ccgggcctcg ggagccggaa gctctcccaa ctccaggccg gccaacggct ggtcgcggtc
     1021 gattcgggcg gcgtagacag cgaacatgac cttgacgata ggttccccac cgcccatccg
     1081 aaaccacaag cccgtgtgac acaccccctc ttgccagccc ccctcagctg cgggcagtcg
     1141 tgccgctggg gcggcacggg tgggcgcagc ggcacccgcc cagcaccggt cagcgccccc
     1201 accccccacc ccgcgcccag cgcacccgca cccgcgtcgg cacacgcacc ggcaaagaca
     1261 agcggccccg cccaccgagg gacgggaccg ctcaccacac cgcagggatc acaccgtcac
     1321 cggcgcgcaa ccccctccgc ccgggccgcc gcggccaccg ccgccgtcac ggccggcgcg
     1381 acccgctcgt cgaacgggga cggaatgacg tagtccgcgg cgaggtcgtc ccccaccacg
     1441 gaggccagcg cctcggccgc cgcgagcttc atgccctcgg tgatccgcga cgcccgcacc
     1501 tggagcgcgc ccgcgaagat gcccgggaac gccagcacgt tgttgatctg gttcgggaag
     1561 tccgaccgcc ccgtcgcgac gaccgccgcg tacttgtggg cgacctccgg atgcacctcg
     1621 gggttcgggt tggccatggc gaacacgaac gcgccctcgg ccatcgaggc caccgccggc
     1681 tccggcaccg taccgccgga gacgccgatg aagacgtccg cacccgcgag ggccgcctcc
     1741 agcgggccag acagtccggc cttgttggtg aaggaggcca gctcctgctt caccggcgtc
     1801 aggtcgtccc ggtcggccga gacgacgccc ttgcggtcgg cgaccgcgac atcgccgatg
     1861 ccggcctcca ccagcatctt ggcgatggcg accccggccg cgcccgcgcc cgagatcacc
     1921 gcgcgcagct cgcccagcgt ccgcccgctc agccgcgccg cgttccgcag ggcggccagc
     1981 gtcacgacgg ccgtgccgtg ctggtcgtcg tggaagaccg ggatgtccag gcgctcctgg
     2041 agcttgcgct cgatctcgaa gcaccgcggc gccgagatgt cctccaggtt gacgccgccg
     2101 aaggagggcg cgagccggac cacggtctcg acgatctcgt cggcgtccgt gcagttcagg
     2161 gcgatcggga ccgcgtccac tccgccgaac tgcttgaaca ggatggcctt gccctccatc
     2221 accgggaggg aggcctcggg cccgatgtca ccgagtccca gcaccgccgt gccgtccgtc
     2281 acgaccgcga cgaccgacga cttccaggtg tagtcgtgga cgaggtcggg ctgctcggcg
     2341 atcgcgctgc acactttcgc gacgccgggc gtgtacgcca gggacaggtc gtccttgtcg
     2401 cggatcggca cggtggcctg cacggccatc ttgccgccgc ggtgcagcgc gaacgcgggg
     2461 tcgaaggcgt cgagcggctc ggcgccctcc ttctgctccg caccggcttc gctgtcgctg
     2521 cgaggattga cgatctccgc tgccactttg tcttacccct taagagttca tggtttgagg
     2581 gtttgtccac tcctggtgag gaatgggcgg gcaccgcaca gggagatgac tgtctgggcc
     2641 acgtggaccc tgcgcgacgg gcgcgccgca cacgcgccct gagcccctga tgaggggtgt
     2701 aaagaacctt cttacccgac ggacgcctcc cgcgacgagt ccgataagcg caagctcaca
     2761 tgccggacct cgaacgccgc atgtcggtga catgactcat agccagggtt ttggacaacc
     2821 tcccaggccc tcttgacaga cctcggatcg aagacatcgg ccgccctgta cacccgcgat
     2881 ccatggcggg ataaggagag attccgcaga tcttccggcc ggaagggcag attcccgcaa
     2941 aggttcggtc gtgatgtacc gacctggtgc ggttcggggg ctgacccgtt atccgatttt
     3001 gacatgacgg gccccctgaa cggccgagtc cgaatggcaa gatgccgtaa tcacacgagg
     3061 tcgcggcact cgaaggtgtg tgctctcgtc gacccacggc accggccggt cccccggccg
     3121 gcgtctcgtc aggaactcca ccgtccccat cggcaactcc ctcatccgcc ggaggaacca
     3181 ccatgaccgc acgcttcacc cgtcgtacga ccgccgcgca ctcccggcta gcagcggtcg
     3241 gtgcgatcgc ggtcgccggc gccctgctgc tcaccggatg cggcgaccag accgagaacg
     3301 gcgactccag cggcagcgac aaccagtccg ccgccggcgc tccgctcgcg gacaagctgc
     3361 cgcagtcgat ccgcgacaag ggcaccatca aggtcggctc ggacatcgcg tacgcgcccg
     3421 tcgaattcaa ggacgactcc ggcaagaccg tcggtatcga cccggacctc gcggacgccc
     3481 tgggcaagca gctcggcgtg aagttcgagt tcgagaacgg caccttcgac accctgatca
     3541 ccgggctgcg ctccaagcgg tacgacatcg ccatgtccgc gatgaccgac accaaggacc
     3601 gccaggaggg catcgactcc gacaccggca agaaggtcgg ccagggcgtc gacttcgtcg
     3661 actacttcac cgccggtgtc tcgatctaca ccaagaaggg cgacaaccag ggcatcaaga
     3721 cctggtccga cctgtgcggc aagaagctcg tgctccagcg cggcacggtc tccgaggacc
     3781 tcgccaaggc cgagaacgag aagtgcccgg ccggcaagaa gatctccatg gaggccttcg
     3841 acaacgacca gcaggcccag acccgcctgc gcgcgggcgg cgcggacgcc ggttcctccg
     3901 acttcccggt ggcggcgtac gcggtgaaga cctcgggcgg cggcaaggac ttcgaactcg
     3961 tcggcgagca ggtcgaggcc gcgccgtacg gcatcgcggt ggccaaggac aacgcgcagc
     4021 tgcgtgacgc cctgaaggcg gcgctggacg cggtgatcgc gaacggcgaa tacaagaaga
     4081 tcatggacaa gtggggtgtg gcggaaggcg ccgtcaccga ggccgccgtc aacggcggca
     4141 agtgaccgcg cggcgggcgc tgaaaggcaa catccgtgac tgttgacatc gacaagacgg
     4201 cgggcggccc ggcgggtaac ccgccgaccc cgccggaggc catcaaggcc atcccggtcc
     4261 ggcactacgg gcggtacgtc tccgcggtcg tcgcgatcgc gctgctggcc gcggtcgtgt
     4321 acgcgttctc gcagggcaag atcaactggg gcgcgatccc ggactacttc ttcgacgacc
     4381 gtgtcctgac cggcatgggc aagacgctgc tgatcaccgt cctcgccatg ctgatcggta
     4441 tcgtcggcgg catcctgctc gccgtgatgc ggctgtcgaa gaacccggtg acctcgtcca
     4501 tcgcgtggtt ctacatctgg ttcttccgcg gcacgccggt cctggtgcag ctggtcgtct
     4561 ggttcaacct cggcctggtc ttcgagtaca tcaacctggg cccgttctac cgcgacgagt
     4621 ggtcggactt catgacgccg ttcctgacgg cgctgctcgg tctcggcctc aacgaggcgg
     4681 cgtacatggc ggagatctgc cgcgccggtc tgctcgcggt cgacgagggc cagacggagg
     4741 cggcgcacgc gctgggcatg agccactcca ggacgctgcg ccggatcgtg gtcccgcagg
     4801 cgatgcgcgt gatcgtgccg ccgacgggca acgaggtcat caacatgctg aagacgacct
     4861 cgctggtgtc ggtcgtccag tacgccgagt tgttcagagt cgcccaggac atcggccaga
     4921 cctcgggcgc cccggccgag atgctgttcc tcgcggcggc ctggtacctg ttgctgacct
     4981 cggtcttcag cgtcggccag tactacctgg agcgctacta cgcccgcggc tccagccgca
     5041 gtctgccgcc gaccccgatg cagaagatca gggcgaacct gttctccctg tcgaaccgct
     5101 ccagcacgac gggaggtgcg gcatgaccgc catggtcaag gccgagggcg tccacaagtc
     5161 cttcggcgcc gtcgaggtcc tcaagggcat cgacctggag gtggagcagg gcgaggtgtt
     5221 ctgcctcatc ggcccctccg gctccggcaa gtccaccttc ctcaggtgta tcaaccacct
     5281 cgagaagatc aacgccgggc gtctgtacgt cgacggcgag ctggtcggat accgccagaa
     5341 gggcgacagg ctctacgagc tgaaggacag cgaggtcgcc cgcaagcgcc gcgacatcgg
     5401 catggtcttc cagcgcttca acctgttccc gcacatgacg gccgtggaga acgtcatgga
     5461 ggccccggtc caggtcaagg gcatgagcag gccccaggcc cgggaacgcg cacgggccct
     5521 gctggagcgc gtgggcctgg gcgacaaggc cggcaactac ccctcgcagc tctccggcgg
     5581 ccagcagcag cgcgtcgcca tcgcccgggc cctggcgatg gacccgaagc tgatgctgtt
     5641 cgacgagccg acctccgcgc tcgaccccga actggtcggc gacgtcctcg acgtcatgcg
     5701 cgacctcgca gagtccggca tgacgatggt cgtcgtcacc cacgagatgg gcttcgcccg
     5761 cgaggtcggc gacagcctgg tcttcatgga cgacggagtg gtggtcgagt cgggcaaccc
     5821 gcgcgacgtg ctgaccgacc cgcagcacga ccggacgaag gcattcctgt ccaaggtcct
     5881 ctgagaccgc gtgagcagag gtcaggggcg gtacggatct ccgtaccgcc cctcggcgtg
     5941 tggtcctact tgaccgccag cagcagggtg tcggacggcg agcaccacac gggccgcgcc
     6001 tcgccgaagc ccttctcgcg cagtacgcgc gcgtgccagg ccgccgaggg catgtcgccg
     6061 tcggcgtgct cgccgtagat ctcgaagcgg cgggcggtgg gcccggccag caccgggtcc
     6121 ttggcggcga gctgccacca ctcggcccag tccagggcgc cctgttcctt ggcggcgtcc
     6181 atccgtgcgt gccgctgggc gcgctcggcc gcgttgatcc ggggcgtcgt gtcgtcgatc
     6241 atgtggtccg cgttcatgaa gacaccaccg tcgcggacca ggtccgcgac ccggccgtag
     6301 agatccgcga gggggtcggc gtgcaaccag tgcagggccg tcgcggtcag cacggcgtcg
     6361 tacgagccgt acggcagctt cgacggccag tcggggtcct tgaggtcggc ggtgacgaag
     6421 gagacccgct cgtcgcccgc gaaggtgccc tcggcgatgg cgaggagcgc ggggtcgagg
     6481 tccaccccgg tgctcgtggc ctgcgggaac cggtcgagca gccgggccgt gatggtgccg
     6541 gtgccgcagg ccaggtccag cacgcgcggc gcggtgccga ccagcgcctc gaccatgtcg
     6601 agcatgatcc ggaaccgttc ctcgcggtcc ggcatgtacc actcctgctg ccggtcccag
     6661 ctctgctgcc aggcctgcca gtcggcaccc gccgcggtgg ccggggtggc ggccggggtg
     6721 gcggtcgtcg tggtggtggt cgtgtccgcg ttcgtcatcg agcccctccg tactgcgtcg
     6781 cgtaataccc tggaagcacg atcagctgtt acctgaccgc aggcacgacc atagagcccc
     6841 tccgtaagga ctacaagtgg aactggccta ttactcggat tacgccgtac gtctcgtcaa
     6901 caccgaggaa ccgtcgcgcg ggcaggactc cctgacctcg gtggaggccg tccgtgacct
     6961 cttcggcgcc aaccagtcgg cggcccggcg cgcgtccgac gccgacgtga cccggttccg
     7021 ctcggtccgg ggacggctgc gcgcggtctt cgaggcggcc gacgggggcg acgagaccct
     7081 cgccgtggac ctgctgaact cactgctcct ggagttcccg gtgagcccgc agatctccgg
     7141 gcacgaccac cgggcggagg acggcagccc gctgtggcac atgcacctgg cggaccaccc
     7201 ctccaacgcg accgccggtt tcgcggccat cgcggcgatg ggcctggcct tccacctcac
     7261 cgagtacggg gtggaccggc tgggcctgtg cgaggcggcc ccctgccgca acgcttacct
     7321 ggacacctcc accaaccgct cccggcgcta ctgctccgac cgctgcgcca cccgcgccaa
     7381 cgtcgcggcc taccgcgccc gcaagcgcct ggaggcggac cggtcggcca gcaccggcct
     7441 gaccgccgac agcacccagc ggaccacggc gagcggcgaa cgctgacccg gccgcggcgg
     7501 gcggtagcgg aaccggaccc tgcccagcac gaggtcctgc gggaccacgc cgtagtcggt
     7561 gctgtccccg cccgcgaacg cgttgtcccc gagcacccac cagccggtcc cgcgccgttc
     7621 ggccgcccgt ttgaccacga gcaggtcctg ctggaagggg tgccgcagga cgaccacgtc
     7681 acccggccgg acccgcgctc cccagtgcac gagcagcacg tcaccgtggt gcagcgtggg
     7741 caccatcgac ggcccggtca cctcggccgg cccgaagggc agcgtccctc tcgcgcgctc
     7801 ggtctcctgc gacagttgct ccggcatcac ccggcacctc cccggtcttt cctccaccag
     7861 tctcagtctc accccggact tttgtcctaa gcccacgggg gcactcgcga aatcgggtct
     7921 cccagggagt aatgtccccc ctgagaagac gatcacgagg aaggaacgct tcatgctttc
     7981 ccgcctgttt gcccccaagg tcacggtcag cgcccactgc gacctgccct gcggcgtgta
     8041 cgacccggcc caggcccgca tcgaggcgga gtcggtgaag gccgtccagg aaaagatggc
     8101 cggcaacgac gacccgcact tccagacgcg cgccacggtc atcaaggagc agcgcgccga
     8161 gctcgcgaag caccacgtct ccgtgctgtg gagcgactac ttcaagcccc cgcacttcga
     8221 gaagtacccg gagctgcacc agctggtcaa cgacaccctt aaggccctgt cggccgccaa
     8281 gggctcgaag gacccggcga ccggccagaa ggcgctggac tacatcgccc agatcgacaa
     8341 gatcttctgg gagaccaaga aggcctgacg gacgtcagca tcctgggccg gcgatcggtg
     8401 caccatcgca ggccgcagga cagcccgaag gggcccggcc gccatccggc cgggcccctt
     8461 cggcgttgcc ggggccagga ggggcccacg gtcggggcct gcccctgacc gcccctcggt
     8521 cctgcgggta gctcagcgct tgcggtggta cgtccgcacc acgacgccgt tgccgaaggt
     8581 ccgcacggag tccgtcacga actcggagac ggcgaaaccg gaggcgaaca tcggcatgcc
     8641 ggtgccgagc accaccgggt agctcttgat gaccagctcg tcgacctcgt cggccagctc
     8701 gccggcgacg gccgcgccgc cgcacaggta gatgtcgaag gcactgtcct ccgccttcaa
     8761 ctccctgacc ctgcccacca ggtcggtcga gatgatctcg acgttcgggt cgggcgactc
     8821 ggtgagcgtg cgggaggcga cgtactcgcg cagatgcgcg tacgggctgg tgacgccctc
     8881 cttgagggcc aggtcgtagc tggccctccc ctgcacgatg gtgtcgaacc gcttgttcgg
     8941 caggtcgtcg atgcccagcg gcctacggcc gtgggtcggc agcgtctccg ggtactccga
     9001 cttcaggaac gcgaagaact cctcgtcgac gaacgggacc atgaacgtgg cgtcgccgtc
     9061 cgggccgccg atgaaaccgt cgatcgagca ggcgacgaag tacgtgagtt tgcgcaaacc
     9121 ggtctcccct tcatgttgac cactacgatc acagtactcc acccgtagtt gtttggggag
     9181 gggattgtcg gggctaccgg gtctgcggct cgcgccacat gggccacatc cgggggccgt
     9241 ccggcaggtc cagggcccgg ccggtgaact cgaacccgag gcgctcgtac agcgccttgc
     9301 cgcgggcact gctcgcctcg aggtaggcgg gcagcctctc gcggtcgcag cggtcgagca
     9361 cgctctcgat cagcgcggtg ccgagaccct cgccctgccg cccggggagc acaccgatca
     9421 tccacaggta ctcatgggcc cgcccggtgg ggtggatgcc gtccgtgagc cgggctatca
     9481 gctccacgcg ctcgttctcc gggtcgacgg cctcgcggat ctgcgcggga gcgtcctcgg
     9541 cggccgtgtg ctcgtccgcc gggacgggca gccacaacgc gcaggcggcg ccgtcctcgg
     9601 tgagatcgat gcgtccgtcg gcgaacacgg cgtcggcaaa cgcggccatg agccggtggt
     9661 gcgtccggcg ccggtactcc tcaccgggga agacccaact gctcaccgga tcgtcctgga
     9721 aggcctcgtc cagcaaccgg acgaccagat cccggtcgtc ctcccccgcc gtccggatca
     9781 ccacacccat acctcacccc tccgactcaa caccgctcgt gtgtacggcg gttgagccta
     9841 acgggtggcc ccgggccctg acgggggaga caaggaggcg ggccccgcac accgtgggga
     9901 agtgcgggac ccgccggacc ggagccgtcg gcggtgcggc cgtacgtcgg tcaggtgccg
     9961 tacggccctg cacgggctcc ggggtcttgc gtggcggcgc tcaggtactg cgccgggtca
    10021 cgaactcggc cagcgcgagc aggccgccgg ccgcctccgg ttcgggcacg gcacgggcca
    10081 gctcctgcat ggccttcgcc atatggtcgg ccgcctgggc ctgcgcccag tcccggccgc
    10141 cggcccgctc cacggccagg gcggtgcgct ccaggtcctc cttgccctcg tcgtacggcg
    10201 ccgcgtacag ctcggccagt tcggcggcgg ccgtggtgcc ggaggtgagg gcggcgacca
    10261 ccggcagtga cttcttgcgg gcggccaggt cggcaccggc cggcttgccg gtgtggcgcg
    10321 ggtcgcccca tatgccgatc acgtcgtcga tgagctggaa ggccagcccg gcctcgcggc
    10381 cgaaggcgtc cagtgcctcg acgtcctccg tggccgcacc cgcgtacagc gcacccaggg
    10441 cacaggcaca gcccagcagg gctcccgtct tggcctcggc catggcaagc gtctcgtcga
    10501 gcgtgacctc gcccggcggg cgccgttcca tggccgtgtc cgcgtgctgg ccctcgcaca
    10561 gctccatgac gcagtcggcg agccgggcgg ccgccgccgc ggacgcgggg tgcgggtccg
    10621 cggcgagcag gcgcagggcg agcgcctgga gggcgtctcc ggcgaggatc gcgtcggcgt
    10681 caccgaacac ggtccacgcg gtcggccggt gtcgccgggt ggcgtcccgg tccatcacgt
    10741 cgtcgtgcag cagggtgaag ttgtggacca gctccaccgc cgcggcggcc cggccggccg
    10801 ccgcgcgggc cgccggcccg ccgagcgcgg tcgccgcggt gaggacgagc gcggggcgga
    10861 tcgccttgcc cgcgttgccc gccgcgggcg tgccgtccgc gtgctgccag ccgaagtggt
    10921 agagcgcgat ccggcgcatc gactcgggca gcgaagcgat ggcggaccgc agttcggggt
    10981 cgaccgatgc ccgtgactcg ctcaggagca cggccgcctc gtgtccttcg gccgcccgtc
    11041 ccggaccgtc ggacgactcc gccggctcct tctcgcgctg tgtaccgatg ggcccgtgcc
    11101 tttccggtgc tccggtggga cgacgcgtcg cggtgccgcc gcgccgggtc tccgtcatgg
    11161 actcaccttc cccctgggcc cgtccgtacc cccggggtgt acccgcccgg gagggcggga
    11221 acaccgcgtt cggggctgcg aggtcaccgc cagcggccga tctcgacgtt ctccaggacg
    11281 ccgagcgcgt ccggtaccag gacggcggcc gagtagtagg ccgtgaccag gtacttgatg
    11341 acggcctgct cattgatgcc catgaagcgc accgacagac tcggctcgat ctcgtccggg
    11401 atgccggtgg cgcgcagacc gatgacgccc tggtcctgct cgccggtacg catcgcgatg
    11461 atcgacgagg tgcgggcctc ggtgaccgga atcttgttgc acgggtagat gggcacaccg
    11521 cgccaggtcg ggatgcggtt cccggcgacg tcgatcgtct ccgggacgag accgcgcttg
    11581 ttcagctcgc ggccgatggc ggcgatggca cgcgggtggg cgaggagcag cttggtgccg
    11641 cgccggcggc tcagcagctc gtcgaggtcg tccgggccgg gcacgccttc gtgcggctgg
    11701 atgcgctggt cgtactcgca gttgtgcagc aggccgaact cgcggttgtt gatgagttcg
    11761 tgctcctggc gctccttcag cgcctcgacc gtcaggcgga tctgctgttc ggtctggttc
    11821 atcggctggt tgtacaggtc ggccacgcgc gagtggatgc gcagcacggt ctgcgcgacg
    11881 ctcagctcgt actcacgggg ccgggcctcg tagtcgacga aggtgtgcgg gatgtccggc
    11941 tcgccgctgt gaccggccgc gaggtcgatc tccttctcac cgtgcttgtt ggtgcgctgc
    12001 tccgggatcg agcgccgctg ctccaggtgc tcgcgcaggg actccgcccg ctccgcgacc
    12061 tgctccacct cctggcgggg cagcaccagc accgtgcagg cggtgaccgt gcgggcggtg
    12121 aactcccaga tggcgtcacc gtcgaggagc gcctggtcgc cgaagtaggc gccgtcggcg
    12181 aggacgccga gcaccgcgtc gtcgccgtag ggaccggtgc cgatcttctc gatcttgccg
    12241 tgcgccagca ggtagacctc gtcggcccgg ccgccgaacg aggcgatgac ctcgccggga
    12301 ccgaactccc gctgctcaca gcgctgcgcg agttccgaca gaacctcgtc gtcctcgtac
    12361 gaccgcaggg ccggcagctc gcccagctcc gcggggatga cctcgacgcg gtcgccggtc
    12421 ttcacgaacg tcacgcgacc gtcgccgacg gcgaaggtca tgcgccggtt gacccggtac
    12481 gtgccgccct ggacgtcgat ccaggggagc gagcgcagca gccagcggga gctgatctcc
    12541 tgcatctgag gaacggactt ggtggtggtg gccaggttcc gcgcggccgc cgtgccgagg
    12601 ctctgctgcg gcctggtctg ctcggtgcgg acctcttcgc ctaccgacat aaggaattgc
    12661 cctcccggtc atgccggacg gctgcgcccg gcatcgatgt gcatggacca gccttcctca
    12721 cggagcgtgc cggtgctatt acacgaaaga gcgggaatgg atcacttgcg gccggggcag
    12781 atatgggggc ttgttcggcg tctcggcgac ttgtccgact cggtccgccc ctgttcgacg
    12841 ccactggccg ggacgagatt ggccgaaacg attcgcacac cgaccgagca agtaataggt
    12901 gaagctccgg ttcggtacaa gctccgtacg aggcggtcgc gtcgggcggt cgtcgcgcag
    12961 cgtgaaggag ccggccgtgg cctcacccat gtccgcgagt agtttcctga aggcactgaa
    13021 ggcggagggt ctcaccgtcg tcgaggtggg cgactggcgg gaccacaatc gcaaccacaa
    13081 gggcccctgg ggccccgtca acggggtgat gatccaccac accgtgaccc ggggcagcgc
    13141 gcggacggtg gagatctgcc gcaaggggca cgagagcctg cccggcccgc tgtgccacgg
    13201 tgtcatcacc aaggacggca gggtccatct ggtcggctac ggccgggcca accacgccgg
    13261 tctcggcgac gacgacgtcc tgcgggccgt cgtcgcggag aaggcgctgc cccgggacaa
    13321 cgaggccaac accgacggca accggcactt ctacggcttc gagtgcgaga acctcggcga
    13381 cggcaaggac ccttggcccg ccgcgcagtt ggacgcgatc gagcgggccg ccgcggccgt
    13441 gtgccgccac cacggctgga acgagcgctc ggtgatcggc cacctcgagt ggcagcccgg
    13501 gaaggtcgac ccgcgcggct tcacgatggc gtcgatgcgg gagcgcatcc gcgaccgcct
    13561 gaagtgagag tgatccaggg accggccgga gtgccccgtg gaccgaccgc agcaccttcc
    13621 ggaccggtcg gcgccatccg cgcaccgacc gcagcacccc tcgcaccggt ctgcgccatc
    13681 cgcgcaccga cggcagcacc ccgcagaaca accagagcgg gcgatccggg gaccggcggc
    13741 cgcggcggcc caccgccggg cgcagtggct ctgggaccgg gccgcgggag gtgtgcgccg
    13801 ggcggcggcg ggacaatggc cgggtgaccg gcaccgacac ccgcgacctc gccgccctgc
    13861 ggccccgtct gccctccccc ctgcacgagg tggccgacgg acggttcgag cggcgcggcg
    13921 tccggttgct gctcaagcgg gacgatctga tccaccccga gctggtcggc aacaaatggc
    13981 gcaagctggc accggtgctc gccgcggcgg acggccgtac cgtcgtcacg ttcggcggcg
    14041 cctactccaa ccacctgcgc gccgcggccg ccgcgggccg gctgctcggg ctgtccaccg
    14101 tgggcgtggt ccgcggtcag gagctggccg gccggccgct caacccgtcc ctggcccggt
    14161 gcgccgccga cgggatgcgg ctgcacttcg tcgaccgctc gacgtaccgg cgcaagtccg
    14221 aaccggagac gctggcggcc ctcctccggg cggtggacgc cgagggcgcc gtcgtcgtcc
    14281 ccgagggcgg cagcaacacg gaggcggtcc gcggctgccg cgccctgggc gaggagctgg
    14341 gcgagcacgc cgacgtggcc gccctcgcct gcggcaccgg tggcaccctc gccgggctgg
    14401 ccgccgggct tccccggggg cggcgggccc tcggcatacc cgtgctcagg ggcggcttcc
    14461 tggagggcga catacggcgg ctccaggaac gcgcgttcgg cgggccgcgc ggcacctgga
    14521 gcctggacga ccgcttccac cacggcggct acgcccgcac gacaccggcg ctggacgcct
    14581 tcgccgagga cttcgaacgc cgccacggcc tccccgtgga gcgcgtctac gtcgccaaga
    14641 tgctgtacgc cctgctcgcc ctcaccgagg agggcgcctt cccgcgcggg acggccctgg
    14701 cggcggtcgt caccggccgc ccctttccct gagccgcacc ggaccaccgc acgcacgcct
    14761 acgcgcccgc gtacgcgtgc acgtacgcgt gcgcgtgctc acgtcgtctc ccggtacgcg
    14821 gcggcctcct ccagatccag ccggcgcagc agggtccgga gcatctcgtc gtcgatgtag
    14881 cggccgtccc gcagccggac gaagacctcg cgctcggcgc tgatcatctc ccgggagagt
    14941 cgccggtagg tgtcgtcgac ggtctcgccg gtgacgggat tgacctggcc gagccgttcc
    15001 cagacggcgt tgcgacggcg ttccaggacc atgcggaggc ggtcggcgag cggcgccggc
    15061 agcgcgttgc gctcgtcggc caggagctcg tccaggtgca gctccgcggc ccgcgaggcc
    15121 tgcgcctgcg cgttggcctc cgccagcgtc tcggcctgca cgtcgtgcgc cgggaacttc
    15181 agcaggcgga tcagcggcgg caggctgacg ccctggacga ccaacgtgcc gatgacggtc
    15241 gtgaaggtga ggaacaggat gaggttgcgc tcggggaagg gctcgccgcc gtgcacggtg
    15301 agcgggatgg agaaggcgat ggccagggac accacgcccc gcatcccggc ccagccgatc
    15361 acgaacggac ccttccagga gaggtcgccc tcgcgcgcgc gtacccgtgc cgacagccgg
    15421 ggcaggaagg tcgccgggta cacccacacg aaccgcgcca ccgcgaccac caggaacacg
    15481 gcgagggcgt accaggcggc gtcgatcccc tcgtactcgc cgaggccctt gaggacgacg
    15541 ggcaactgga gtccgatgag ggcgaacacg gccgactcca ggacgaaggc gaccatcttc
    15601 cacaccgcct cctcctggag ccgggtggcg aaatcgacct cccacgcgcg gtgccccagg
    15661 tagagcgcga cgacgaccac cgcgagcacc cccgaggcgt gcacctgctc ggcgaccgcg
    15721 taggcgacga acgggatcag cagggagagc gtgttctgta gcagcgcctc cgtcaggtgg
    15781 gtgcgcagcc agtgcagcgg caccatcagg accagtccga cgccgacgcc gcccaccgcg
    15841 gcgatcagga actcgccgat cccgccggcc caggtggcgc cctcgccgac ggccgccgcg
    15901 agcgccacct tgaaggcggt gatggcggtg gcgtcgttca ccagggactc gccctggagg
    15961 atcgtggtga tccgggaggg cagtcccacg cggcgggcga cggccgtggc cgcgaccgcg
    16021 tccggcggcg ccaccaccgc gccgagcacc agggccgcgg tcagcggcag gcccggcacg
    16081 atgaggtacg cggcgcagcc gacgacgaag gtggcgaaca ggacgtagcc cacggacaac
    16141 agcgccacgg gccgtgcctg cgcccgcagg tccaggtacg agctgtcggt ggccgccgtg
    16201 tagagcagcg ggggcagcag caggggcagg acgatgtgcg ggtcgagggt gtagtcgggc
    16261 acgccgggca cgtagctcac cgccaggccc gccgcgacca gcagcagcgg caccggcacc
    16321 ggcacccgcc gtcccgccgc ggcgatcgcg gcgctccccg ccaccagcag cagcagcggc
    16381 atcacgtcca ttgtcctcgc ccgccctcgt cttccgcgcg gtcatccgca cacccgtcgt
    16441 aacctggcaa tcatgaaaca gtgcacgcac gccgacgcgc tgccgcaccc ggaacccgag
    16501 ccgtgcggcg agacctgtcc ggagtgcctg gccgagggca cggatccggt gcagctgagg
    16561 ctgtgtctca gctgcggcca tgtcggctgc tgcgactcct cgccgaggca gcacgcgacg
    16621 gcgcattaca aggagaccgg tcacccggtg atgcggacct tcgagcccgg ggagagctgg
    16681 cgctggtgct tcgtcgatca cgtcctcgtg tgacctctgc ccgggacggt tcgaccgtct
    16741 gacgtctggg tacgtcaacc cggcgcgcgc tcttccgatt tgagcccgcc gaccccctag
    16801 ccactgtgcg tgttcgcgtg tttactatga gtgacagcat gggcttgggg tctcggggac
    16861 aggaaacttc ggagcgcgat aacgtcaccg ctgaaccacg tatcgcgtta acccgagggg
    16921 cgtccctcgg ccctgtaacg cttgtaccac cttggaggtg agggtgtccc agatcgcagg
    16981 cgagcccgcg acccaggact tcgtcgaagt ccggctgccg gccgcgggtg cctacctgtc
    17041 ggtgctgcgt acggcgacgg ccggcctcgc agctcgtttg gacttcaccc tcgacgagat
    17101 cgaggacctg cgcatcgcag tcgacgaggc ctgcgcgatc ctgcttcagc aggccgtgcc
    17161 cggctcggtg ctcagttgtg tcttccgcct cgtcgacgac tcgctcgagg tcaccgtctc
    17221 ggcgccgacc acggacggcc acgccccttc gcgggacacc ttcgcctgga cggtgctctc
    17281 cgccctcgcg ggcaaggtct cctccgccgt ggacgaggac aaaaccgttt cgatcagcct
    17341 ctacaaacag cgcggcgcgg gacccgggcc ggcgtgaggg acggggacgg gccggtgcgg
    17401 gacgaagagc gcgggacacg ggagctgccg gccgagggca cacgttctcc gaacgaggca
    17461 cggcgcacgg cggacggcat cgacggcatt cccgagcagg cccggccgca tccggaggac
    17521 gagacctcgc ccgaggccgt cgttccgggc gacgggcagc ggaccgggga cacccccgtc
    17581 cgtcccgtcc gagcggaggc gggggctcgg gaaagggcaa cgggcgggac gatgagcgag
    17641 cacgagcgac actccgaggg gcaggcgccg ggcgcacggg gcgcgcaggg cacacggcac
    17701 gacccgcagg accgcagcgg tgcgcgcctc ctcttcgccg agctgcgcac gctgacgaag
    17761 gacagtccgg agtacgcgga gctgcgcaat cggctggtcc gcatgcacct gccgctggtc
    17821 gagcacctcg cgcggcgctt ccgcaaccgc ggcgaaccgc tggacgacct cacccaggtc
    17881 gccaccatcg gactgatcaa gtcggtggac cgcttcgacc cggaccgcgg agtggagttc
    17941 tccacgtacg cgaccccgac ggtcgtcggc gagatcaagc ggcacttccg ggacaagggc
    18001 tgggcggtgc gcgtcccgcg ccggctccag gagctgcggc tggccctgac gacggccacg
    18061 gcggagctgt cgcagctgca cggccgctcc cccacggtcc acgagctggc cgagaagctg
    18121 tcgatctcgg aggaggaggt cctggagggc ctggagtcgg ccaacgcgta ctccacgctg
    18181 tccctggacg tcccggacac cgacgacgag tccccggcgg tcgccgacac cctcggcgcc
    18241 gaggacgagg ccctcgaagg ggtcgagtac cgggagtccc tcaagccgct cctcgaagac
    18301 ctgcccccgc gcgagaagcg catcctgctc ctgcgcttct tcggcaacat gacccagtcc
    18361 cagatcgcgc aggaggtcgg gatctcacag atgcacgtct cccggctgct ggcccgcaca
    18421 ctggcacagc tgcgggagaa gctcctggtc gaggagtagc cgccgggtcg ggcgcggcct
    18481 gggcgccgcc gtccggcacc cccggggcta cttctcggcg ctgccgggcc cccggatgcc
    18541 gagggcctgg gtggtcgtgg gattgacgag cagcaccagc gcggtgacgg ccacgacacc
    18601 gagcacgatg ccggccggga cggccaggct gtcggcgcgc accatgttgt aggcgacggg
    18661 cagcgccatg atctgtgtga tcacggcggg cccacggctc cagcccttcc ggccgatcag
    18721 tccgcgggcg gcgagcagcg gcagcagggc gagcacgatc agggtgacgc cgccggtgac
    18781 ggccgaggtc cggtcgtcgg ggtgcccggt gaggccctcc acgagcatcc aggcaccgcc
    18841 gacgacgagc gccagccctt ccagcgcggc gagcgcggcc gcggcggtca gccgcccggg
    18901 gcggggatcc gccgcttcgg cacgggcatc ggcgtcggcg gccgcggagg cgggggtggt
    18961 gggggtctgc tcactgctca cccctgaagg gtagccctcg gcccgtacgc gcccgcccgg
    19021 gtgtcgggcg tatcacgcac ccggtgcgcc ggtggcgatc ttcacatcgg tctgggccga
    19081 gtaccaccca gtaggtaccc tgcacagcat gcgtgcactt ctcgtggtca acccggcggc
    19141 aaccaccacg agcgcgcgca cgcgcgacgt gctgatccac gcgctcgcga gcgagatgaa
    19201 gctggaagcg gtcacgaccg agtaccgcgg ccacgcgcgc gacctcggcc ggcaggcggc
    19261 gcagagcgac gacatcgacc tggtggtggc cctcggcggc gacggcacgg tgaacgaggt
    19321 cgtcaacggt ctgctgcacg cgggtcccga ccccgagcac ctgcccggtc tcgcggtggt
    19381 ccccggcggt tccaccaacg tcttcgcccg cgccctcggc ctgcccaacc acgcggtgga
    19441 ggccaccggc gccctgctgg acgccctgcg tgagggcagc gagcggaccg tcggcctggg
    19501 cctcgcgtcg ggtacgccgg gctcggagga cgagggggtg ccggcccgct ggttcacctt
    19561 caacgccggt ctgggcttcg acgccggcgt ggtcggccgc gtcgagcagc accgcgagcg
    19621 gggcaagaag tcgacgcacg ccctctacgt ccgccaggtg gtgcgccagc tcatcggcga
    19681 gccgcaccgc cgcagcggga cgatcaccct ggagcgggcg ggcgaggacc cggtcaccga
    19741 tctggtgctg tccatagttt cgaacacctg cccctggacg ttcctcggca accgcccgat
    19801 ctacgcctct cccgaagcct cgttcgacac cgcgctcgac gtcttcgggc tcagccggct
    19861 gtcgacggcc gcggttgccc ggtatggcac ccagttgctc acttcgtccc ccgagcgcgg
    19921 gccgcgcggc cggcacgcgg tctccctgca cgacctgacc gacttcacct tgcattcgaa
    19981 ggtgcctctg ccccttcaga tggacggtga ccacctcggg ttgcgtacca gcgtggcgtt
    20041 cacaggcgta cgccgtgcac tgcgtgtgat tgtgtgagca gaaggggcga aagtcctttc
    20101 actcgaacgt ttagaccagg gtccacccca tggaagtacg gctgtgacct agtcgacacc
    20161 gaagaatcaa aaaaaacttt ccggaagggg ttgtatccgc cgccgaggtt tgcgagtctc
    20221 ttcttggcga tcgggacagc ccgcaggacc ggcatccaca gatcaccgga acccctcttc
    20281 aaaccacagg accacgccag ggaacctggc ggtaggccct tcccttgttg agggattcgt
    20341 gaaagcgttc acattcacaa gcatcccagc atgtaatacc aaggagaggt agcagccatg
    20401 gactggcgtc accgcgccgt ttgccgcgag gaagaccccg agctcttctt ccccatcggc
    20461 aacaccggtc ccgcgctgct gcagatcgag gaagccaagg ccgtctgccg tcgctgcccc
    20521 gtcatggagc agtgcctgca gtgggcgctc gagtccggcc aggactccgg cgtctggggt
    20581 ggtctcagcg aggacgagcg ccgcgcaatg aagcgccgtg ccgcccgcaa ccgggctcgt
    20641 caggcctccg cctgacaacc cacccctact gacagcctca gcttggcggc gcgtacagcg
    20701 agtacgcatc ccccgctccc gagccgcagc gcgcagtacc ccccgatgcg catcggacga
    20761 tgtatcgcac gagcactggc ctcggacctt caccggtccg gggctttttg ctgtgcccac
    20821 gccccggtcc cgttgcgcgc cgttacttct cggcgggcac cgggatgtcg aggatgaccc
    20881 gggtgccgcg ctccgaggcg gggaccatgt cgaaggtgcc gcccagctcg ccctccacca
    20941 gggtgcggac gatctgcagg ccgagattgc cggagcggtg cgggtcgaag tcctcgggca
    21001 ggccgacgcc gtcgtcctgg acggtgacca gcagccgggc ctccttcgtc gtaccgccgc
    21061 ggaccgcgga gacctcgacc gtgccggtgt cgccgtcccg gaagccgtgc tccagggcgt
    21121 tctgcaacac ctcggtgagg accatcgaca gcggggtg
//
