LOCUS       NZ_KZ195574            21176 bp    DNA     linear   CON 06-SEP-2024
DEFINITION  Streptomyces sp. CS113 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ195574
VERSION     NZ_KZ195574.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS113
  ORGANISM  Streptomyces sp. CS113
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8695358)
  AUTHORS   Malmierca,M.G., Gonzalez-Montes,L., Perez-Victoria,I., Sialer,C.,
            Brana,A.F., Garcia Salcedo,R., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Searching for Glycosylated Natural Products in Actinomycetes and
            Identification of Novel Macrolactams and Angucyclines
  JOURNAL   Front Microbiol 9, 39 (2018)
   PUBMED   29441046
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8695358)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Searching for glycosylated natural products in actinomycetes
            isolated from leaf-cutting ants: activation of two silent clusters
            and identification of a novel macrolactam
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8695358)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAY-2017) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 78.17x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002188365.1-RS_2024_09_06
            Annotation Date                   :: 09/06/2024 02:31:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,790
            CDSs (total)                      :: 7,719
            Genes (coding)                    :: 7,614
            CDSs (with protein)               :: 7,614
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 1 (5S, 16S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 105
            CDSs (without protein)            :: 105
            Pseudo Genes (ambiguous residues) :: 0 of 105
            Pseudo Genes (frameshifted)       :: 35 of 105
            Pseudo Genes (incomplete)         :: 81 of 105
            Pseudo Genes (internal stop)      :: 4 of 105
            Pseudo Genes (multiple problems)  :: 15 of 105
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:56:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1936176
            Orig. end                         :: 1957352
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ195574.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Salas's laboratory, A.
            Microbiology, University of Oviedo, Spain.
FEATURES             Location/Qualifiers
     region          1..21176
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="12"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..21176
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21176
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11176](-)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11176)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     misc_feature    complement(126..141)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     gene            563..1156
                     /gene="cysC"
                     /locus_tag="B9W62_RS08420"
                     /old_locus_tag="B9W62_08430"
     CDS             563..1156
                     /EC_number="2.7.1.25"
                     /GO_function="GO:0004020 - adenylylsulfate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cysC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999824.1"
                     /locus_tag="B9W62_RS08420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_08430"
                     /product="adenylyl-sulfate kinase"
                     /protein_id="WP_179235393.1"
                     /transl_table=11
                     /translation="MTTTTGPTPSGPSTSRENHVTTGATVWLTGLPSAGKTTIARALAD
                     RLREEGRRVELLDGDEIREFLSAGLGFDRADRHTNVQRIGFVAELLARNGVTALVPVIA
                     PYADSRDAVRERHGANGTAYVEVHVATPVEVCSVRDVKGLYAKQAAGELTGLTGVDDPY
                     EEPVKPDLRIESQDQTVQESAAAVHALLTERGLA"
     gene            1153..2091
                     /gene="cysD"
                     /locus_tag="B9W62_RS08425"
                     /old_locus_tag="B9W62_08435"
     CDS             1153..2091
                     /EC_number="2.7.7.4"
                     /GO_function="GO:0004781 - sulfate adenylyltransferase
                     (ATP) activity [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cysD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071495.1"
                     /locus_tag="B9W62_RS08425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_08435"
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="WP_087806578.1"
                     /transl_table=11
                     /translation="MTTTVAAAREGTAGPYALSHLDALESEAVHIFREVAGEFERPVIL
                     FSGGKDSILMLHLALKAFAPAAVPFSLLHVDTGHNFPEVLDYRDRTVERHGLRLHVASV
                     QDYIDRGVLKERPDGTRNPLQTLPLTEKIQAEKFDAVFGGGRRDEEKARAKERVFSLRD
                     EFSQWDPRRQRPELWNLYNGRHAPGEHVRVFPLSNWTELDVWQYIAREGIELPQIYYAH
                     EREVFARSGMWLTAGEWGGPKDGERTEKRRVRYRTVGDMSCTGAVDSDADSIEKVIAEI
                     AVTRLTERGATRADDKMSEAAMEDRKREGYF"
     gene            2094..3449
                     /locus_tag="B9W62_RS08430"
                     /old_locus_tag="B9W62_08440"
     CDS             2094..3449
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387813.1"
                     /locus_tag="B9W62_RS08430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_08440"
                     /product="sulfate adenylyltransferase subunit 1"
                     /protein_id="WP_087806579.1"
                     /transl_table=11
                     /translation="MTSTTEPVEPLSVWQLSETTLLRFATAGSVDDGKSTLVGRLLHDS
                     KSVLTDQLEAVERASASRGQDVPDLALLTDGLRAEREQGITIDVAYRYFATPRRRFILA
                     DTPGHVQYTRNMVTGASTAELTVILVDARNGVVEQTRRHAAIAALLRVPHVVLAVNKMD
                     LVDYRESVFAAIAEEFTAYATELGVPEVTAIPISALAGDNVVEASAVMDWYGGPTVLEH
                     LETVPVSHDLAHCHARLPVQYVIRPQTAEHPDYRGYAGQIAAGTFRVGDEVTVLPSGRT
                     SKVSAIDVLGEPVDAAWTPQSVTLLLEDDIDVSRGDLIVPSEDAPATSQDVEATVCHVA
                     DAPLTVGHRVLLKHGTRTVKAIVKDIPARLTLDDLSLHPHPGQLVANDIGRVKVRTAEP
                     LPADSYADSRRTGSFILIDPSDGTTLTAGMVGESFAAPEPVKDAADADGWDF"
     gene            3683..4786
                     /locus_tag="B9W62_RS08440"
                     /old_locus_tag="B9W62_08450"
     CDS             3683..4786
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0042918 - alkanesulfonate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030652.1"
                     /locus_tag="B9W62_RS08440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_08450"
                     /product="aliphatic sulfonate ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_087806581.1"
                     /transl_table=11
                     /translation="MPATTALRRTLAVIAALPLLTLAACGYGSQAKDDDTAKVAEGAEK
                     IDGLDSVRIGYFGNITHATPLVANQKGFFQKALGATEAKYAVFNAGPSEIEALNSGSID
                     IGWIGPSPAVNGYAKSDGKNLRIIGGSASGGVKLVVNPDRIKSLKDVKGKRIATPQLGN
                     TQDVAFLNWIAEQGWKVDAQSGKGDVTVVRSDNKVTPDAYKTGSLDGAWVPEPTASKLV
                     AEGGKVLLDESTLWPDKKFVITNIIVSQKFLEEHPKAVEAVLKASVDTNEWITAHPDEA
                     KTAANAQLAKDSGKALPADVLDPAWESIRLTDDPLASTLDAQAEHAVKAGLLDRPDLNG
                     IYDLTLLNKVLKAKGKPAVDDAGLGVE"
     gene            4820..5614
                     /locus_tag="B9W62_RS08445"
                     /old_locus_tag="B9W62_08455"
     CDS             4820..5614
                     /EC_number="7.6.2.14"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972825.1"
                     /locus_tag="B9W62_RS08445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_08455"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_087806582.1"
                     /transl_table=11
                     /translation="MATTTTLAKAADGTESADYAARIEHVSKSFAGPAGQQLVLDDITL
                     DVAPGEFVTLLGASGCGKSTLLNLVAGLDRPSAGGISTDGRPALMFQEHALFPWLTAGK
                     NIELALRLRGVPKAERRDKAEELLELVRLKGAYGKRVHELSGGMRQRVAMARALAQESK
                     LLLMDEPFAALDAITRDVLHDELTRIWRETQVSVLFVTHNVREAVRLAERVVLLSSRPG
                     RIAREWTVGIPQPRRIEDTAVAELSVEITEELRGEIRRHGQH"
     gene            5601..6512
                     /locus_tag="B9W62_RS08450"
                     /old_locus_tag="B9W62_08460"
     CDS             5601..6512
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004981844.1"
                     /locus_tag="B9W62_RS08450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_08460"
                     /product="ABC transporter permease"
                     /protein_id="WP_087806583.1"
                     /transl_table=11
                     /translation="MASTDTTRPARDPGAKDGGDLAGLEAGLDALESVQQGRTPLRQTL
                     VEKVLPPTVAVLLVLAVWQALVSFKIVDDPTKLPAPSDVWDVLHQAWLQGELLGYIWTS
                     VSRGLLGFCFALIIGTPLGLLVARVKFVRAAIGPILSGLQSLPSVAWVPPAVIWLGLNN
                     SMMYAVILLGAVPSIANGLVSGVDQVSPIFLRAGRTLGATGLKGTWHIVLPAALPGYVA
                     GLKQGWAFSWRSLMAAEIIASFPDLGVGLGQLLENGRNASDMAMVFEAILLILVVGIAI
                     DLLIFSPLERWVLRSRGLLVKG"
     gene            6521..7267
                     /locus_tag="B9W62_RS08455"
                     /old_locus_tag="B9W62_08465"
     CDS             6521..7267
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972827.1"
                     /locus_tag="B9W62_RS08455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_08465"
                     /product="sirohydrochlorin chelatase"
                     /protein_id="WP_087806584.1"
                     /transl_table=11
                     /translation="MSAPARPVLLVVAHGSRDPRHAQAVHALVRRVRALRPDVRVETGF
                     LDFNVPSVRGVLESLETEGVRDVVALPLLLTRAFHAKADIPAVLAAAPPRLRIRQAEVL
                     GPSPLLLSALERRLYEAGLTPADKSSTGVVLASAGSSDPEAIAVIADIAREWRHTGWCA
                     VRPAFASASLPRTEDAVRRLRALGCARVAVAPYVLAPGFLPDRIARGAAEADVLADVLG
                     PAPEVARVLLERYDAARMPVALAVGA"
     gene            complement(7289..7837)
                     /locus_tag="B9W62_RS08460"
                     /old_locus_tag="B9W62_08470"
     CDS             complement(7289..7837)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030649.1"
                     /locus_tag="B9W62_RS08460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_08470"
                     /product="DUF1697 domain-containing protein"
                     /protein_id="WP_087806585.1"
                     /transl_table=11
                     /translation="MTTMYAALLRGINVGGGRKVPMADLRALLTSLGHDAVRTHLQSGQ
                     AVFASDHGDEESLAAELATAVEGRFGFPVDVLVRDHAYLKGIVEACPFPAAELEARQLH
                     VTYFSAPVDAERFAAIDAPAFRPEEFRLGDRALYLYAPDGLGRSKLAEALARPRVTKGL
                     IATSRNWNTVAKLVELTRP"
     gene            complement(8113..8454)
                     /locus_tag="B9W62_RS08465"
                     /old_locus_tag="B9W62_08475"
     CDS             complement(8113..8454)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9W62_RS08465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B9W62_08475"
                     /product="hypothetical protein"
                     /protein_id="WP_087806586.1"
                     /transl_table=11
                     /translation="MNTRHTTAKTAPMTTAAVLTLTLLGTVFSSPATAAPRQGDFTATG
                     VKIHESYSTTSSARGHGNPGDGYTWMGGQANAEAVPCPDGSVKDHWTYVHNNRTGVEGY
                     VSDCFIREY"
     gene            complement(8552..9982)
                     /locus_tag="B9W62_RS08470"
                     /old_locus_tag="B9W62_08480"
     CDS             complement(8552..9982)
                     /NRPS_PKS="Domain: Beta_elim_lyase (41-417). E-value:
                     3.2e-73. Score: 238.4. Matches aSDomain:
                     nrpspksdomains_B9W62_RS08470_Beta_elim_lyase.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552727.1"
                     /locus_tag="B9W62_RS08470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_08480"
                     /product="tryptophanase"
                     /protein_id="WP_256976239.1"
                     /transl_table=11
                     /translation="MEPYRIKAVEPIPTTTRAQRARALDRVGYNLFGLRAEEVTIDLLT
                     DSGTGALSAAQWAAAAAGDESYAGSRSFHRFRAAVTELTSYPHVLPVHQGRAAERVLFS
                     ALLVPGRITLSNTHFDTTRANVELSGCQARDLPCARARNLHSPEPFKGDIDLDGLAAEL
                     RGPDAARIALVIMTLTNNGEGGQPVSMDNLARAAALCREHGVPLFLDAARFAENAYLVT
                     QCESGYGGRSPTDVAKEAFRLADGCLMSAKKDGIVHIGGFLGLRDEALARRCEPILIAT
                     EGFPTYGGLAGRDLEMIVQGLTEALDPHYLRSRAEAAAHLAGLCRGAGVRLVEPPGLHA
                     LYLDAGHLLPHIAPHRFPGHALACALYLEGGIRSVELGSLYLGKEDGNGDPVTTAPYEL
                     LRLALPRRTYTRSHLDHVGQTLEAVVKDKDRVPGYRVVEDAPILRHFRARLEPEPAGPG
                     TDVTTGEAPEDEGRADHW"
     aSDomain        complement(8732..9859)
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9W62_RS08470_Beta_elim_lyase.1"
                     /evalue="3.20E-73"
                     /label="B9W62_RS08470_Beta_elim_lyase.1"
                     /locus_tag="B9W62_RS08470"
                     /protein_end="417"
                     /protein_start="41"
                     /score="238.4"
                     /tool="antismash"
                     /translation="DLLTDSGTGALSAAQWAAAAAGDESYAGSRSFHRFRAAVTELTSY
                     PHVLPVHQGRAAERVLFSALLVPGRITLSNTHFDTTRANVELSGCQARDLPCARARNLH
                     SPEPFKGDIDLDGLAAELRGPDAARIALVIMTLTNNGEGGQPVSMDNLARAAALCREHG
                     VPLFLDAARFAENAYLVTQCESGYGGRSPTDVAKEAFRLADGCLMSAKKDGIVHIGGFL
                     GLRDEALARRCEPILIATEGFPTYGGLAGRDLEMIVQGLTEALDPHYLRSRAEAAAHLA
                     GLCRGAGVRLVEPPGLHALYLDAGHLLPHIAPHRFPGHALACALYLEGGIRSVELGSLY
                     LGKEDGNGDPVTTAPYELLRLALPRRTYTRSHLDHV"
     misc_feature    complement(9953..9967)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            complement(10001..11176)
                     /locus_tag="B9W62_RS08475"
                     /old_locus_tag="B9W62_08485"
     CDS             complement(10001..11176)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0009820 - alkaloid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388029.1"
                     /locus_tag="B9W62_RS08475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_08485"
                     /product="tryptophan dimethylallyltransferase family
                     protein"
                     /protein_id="WP_256976241.1"
                     /sec_met_domain="indole_PTase (E-value: 1.3e-124, bitscore:
                     414.6, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFFPRRTPEAAMNPPAPSGYALPPRRSTGAVPAAPTLREHLAGQ
                     LRRLLAAADVTCRWARDAERLLPGLLGPAAGRPLGAGPLSPSFVSDDHSPAELSVSFAA
                     DGAPTVRVLVEPGCGAGTFADGGRAGLRALDRMARCWDVDAEPVARVTDLFLPAAARGP
                     FSLWCAMDLRRTGPPGVKVYLNPEAHGRDRAGEVVEEALTRFGFRSAWPALTARAASWC
                     PDRGRLLFFALDLGHWREPRVKLYIAHQGFSVEEAEAAAGLLPGADPRRAGDFCRTIGG
                     GTRRFDGLPLVSCLSFTRRDRERPSGHTLHVPVRDYARDDRVARDRAAAVLGARGGDVA
                     LLDKALAAMTSRHLSDGVGLISYVSLARSTGGPPRVTVYLSPEAYAVHPPH"
     gene            11310..14243
                     /locus_tag="B9W62_RS08480"
                     /old_locus_tag="B9W62_08490"
     CDS             11310..14243
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019329073.1"
                     /locus_tag="B9W62_RS08480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_08490"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_087806587.1"
                     /transl_table=11
                     /translation="MRSTYEFGILGPLLVRRSGAPVHVNAAKLRMLLASLLVEADRVVT
                     VDALVHRLWGDAPPLRARNTLQNYVLRLRRALGSPADTGPVRTRPHGYLIETDPQTLDV
                     RRFTSLVRLGRTALEQNTAERAAALLRQALELWRGDPLCDLPGDAFPELRLTLREQHLA
                     ALELRIDADLAAGRSADVLPELRALVEAHPLREHFWAQRMLALYRCERQSEALECYRTV
                     TALLTEELGVTPGPALRDMHARLLAAAPDLGRPPGGAAAAASPTAPGRPALPVETTGFI
                     GREAQLAQVRALLSTARLVTLTGVGGVGKTRLALRSAAQLAASYADGVHLADLAALTSP
                     DLLDRAVAEALGLRDQSARPPAQALVDALRDRQLLLLLDNCEHVADAVAGLVLRLLRAA
                     PGLTVLATSRHRLGVPGEHILTVPCLTLPEPDAGCDARQPPERSESARLLVQRAAASAP
                     AFAITARNRAAVAQLCRRLDGIPLAIELAAVRLGAMTAEEMLERLDDRFRVLCLPDMPG
                     TETRYQHTLRGVIDWSHTLCTPRERLLWARLSVFSGGFDLSAAEAVCAGEGVEREEILD
                     LLAALVNKSLVAVDSTGPRARYGMLETIRQYGLERLGELTRQTGLRIRHGAHYRAMTLR
                     AGAEWCGPDEVDWLLRLREELPNLRTALDFCATRPEHVGTAVAIAVDLARTRCWFFSSV
                     LGEGRYWLERLLAAAPALPPDLTVGALAMKVWIALCQGDNPAAERFLAECRAQAAGSDG
                     PAVAPFTFIEGAHALLVDGTSASIPLLAAAREQFLRDGRRGDAHMATMMWAMAEAFLGD
                     PVSARAAAGEYTAEAEAGRAPWARTWARWCAGLVELRHGDPAAALAPLRDALARQNSFG
                     DNWGPVWGVETLAWAVAETDRYTDAARLLGAAHRLRQDTGVALTGLRPFHDAHAAAERR
                     VRAALTTQEYARARAYGAAQNSVLLALRISAEPGGDPRAEEVTDPGA"
     gene            14464..16734
                     /locus_tag="B9W62_RS08485"
                     /old_locus_tag="B9W62_08495"
     CDS             14464..16734
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030648.1"
                     /locus_tag="B9W62_RS08485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_08495"
                     /product="MMPL family transporter"
                     /protein_id="WP_087806588.1"
                     /transl_table=11
                     /translation="MRNRETRVRGIAARAGGWSARHRWAAVGIWVLFVVLAMGLGSAAG
                     RVDVKDSDQMGGETRTAARIVEDAGIDEPAGETVLIQAKSGDLLATDAEFRAAVGAVVT
                     AVEATGKVTGVTSPYDTKTISKDNRSALVQFDMRGEADTAGERVEPVLKAVEGVQKEHA
                     SLRIEEIGGASMMKTFDDAFGDDFKKAEYSAVPVALGILLVAFGALVAALVPVALAITA
                     IIATMGLMGLVSHFQPMSETANSVMLLVGLAVGVDYCLFYLRREREERAAGRDARTALR
                     IAAATSGRAIVVSGVTVCVAMAGMLFTGIAEFEAMGLASLMVVAVAMVGSVTVLPALLS
                     LLGERVEKGRVPFLRRRRPSGGTGEGSRFWTAVLKRVLARPLLAAVVAVGALLAVAAPA
                     LGMKTQNLTLDQEFGDSLPIVQTYNRVNEAFPGGSDPAEVVVKADDINAPEVRAALADF
                     RERAISSGASRGPVDITTHDEQNVALVYVPLVGGSDQDKAGESLDKLRDDVRPATLGKV
                     DGVEAPITGQVAGNKDFNDQLVGSVLPVFAFVVVFAFLLMLLSFRSLTIALTSIVLNLL
                     SVGAAYGILVAVFQHGWGASLVGAEGVGAIITWLPLFLFVILFGLSMDYHVFVVSRIRE
                     ARLRGRSTRDAIQHGVVTTAGVVTSAAVIMVAVFAIFGTLSMQSMKQMGVGLAAAVLID
                     ATIIRGVLLPAVMSLLGERNWYLPKWLHRLPDLTHDESPEAIASPERDGESERGERGKP
                     VGV"
     gene            complement(16810..18066)
                     /locus_tag="B9W62_RS08490"
                     /old_locus_tag="B9W62_08500"
     CDS             complement(16810..18066)
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972830.1"
                     /locus_tag="B9W62_RS08490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_08500"
                     /product="glycosyltransferase"
                     /protein_id="WP_087806589.1"
                     /sec_met_domain="MGT (E-value: 6.3e-44, bitscore: 149.6,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRKQLHETSRLAYGRRMTSRPAHIAMFSIAAHGHVNPSLEVIRE
                     LVARGHRVTYAIPPLLADKVAEAGAEPKLWNSTLPGPDADPEAWGSTLLDNVEPFLDDA
                     IQALPQLAEAYEGDEPDLVLHDIGSYTARVLGRRWDVPVISLSPCMVAWEGYEQEVGEP
                     MWEEPLKTERGQAYYARFHAWLEENGITDHPDPFVGRPDRSLVLIPKALQPNADRVDEK
                     TYTFVGACQGDRAAEGDWTRPEGAEKVVLVSLGSAFTKQPAFYRECVRAFGELPGWHTV
                     LQVGRHIDPAELGDVPDTVEVRTWVPQLAILQQADLFVTHAGAGGSQEGLATATPMIAV
                     PQAADQFGNADMLQGLGVARTLPTEEATAEALRTAALALVADPEAARRLKEIQAQMAQE
                     GGTRRAADLIEAELAAARG"
     gene            complement(18063..18845)
                     /gene="erm(O)"
                     /locus_tag="B9W62_RS08495"
                     /old_locus_tag="B9W62_08505"
     CDS             complement(18063..18845)
                     /codon_start=1
                     /gene="erm_O_"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972831.1"
                     /locus_tag="B9W62_RS08495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_08505"
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(O)"
                     /protein_id="WP_087806590.1"
                     /transl_table=11
                     /translation="MARPTPRARTLSQNFLADRATAAHVARLAAPDGRQPPLLLEVGAG
                     DGALTEPLARRSRELHAYEIDPRLVPGLRARFARTPHVHVVAGDFLAARPPRTPFAVAG
                     NVPFSRTADIVDWCLAAPGLTDATLLTQLEYARKRTGDYGRWTLLTVLTWPRHEWRLLG
                     RVGRHRFRPAPRVDAGILRIARRRTPLLTGAGARRTWSDLVELGFSGVGGSLHASLRRT
                     HPRRRVDAAFRAARLDPGVLVGEVAPDRWLRLHEELTA"
     misc_feature    complement(19129..19140)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 16.98"
                     /tool="antismash"
     gene            complement(19275..20567)
                     /locus_tag="B9W62_RS08500"
                     /old_locus_tag="B9W62_08510"
     CDS             complement(19275..20567)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387824.1"
                     /locus_tag="B9W62_RS08500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_08510"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_087806591.1"
                     /transl_table=11
                     /translation="MTRTPTRILTLFACAVLLLAGCSGGGDGADDGRITLRFQSLAWQD
                     ESVQANRELVREWNATHPDVRVEYVQGSWDSVHDQLLTSFEGGEAPDIIHDASDDLADF
                     AYGGYLADLSELLPARLRSDIPRHSWETVTFGDGVYGVPFLQEPRVLIANATLLEKSGV
                     RIPTPEHPWTWEEFRQVTKELSGDGTYGVAWPLKEPVSATLNLSLSTGGKLFHRGADGR
                     VTVRFEEGDQVVPRTIHDQVDTDRSASPTTLGSGGSDTLPGFFAGKYAMVPLGFSYRQQ
                     IEQQAPEGFDWRVLPAPAGADGLAQGVSPQTLSVAEDSPHRKEAAAFVDFLLQPDNMVR
                     LALGDWMLPTGEQALKDPALHTAEHGWATGTALAAHLRSAPAQSVRGYAEWKDKVATPA
                     LQEYYSGAIGADELRHRLEEDGNLVLARYQR"
     misc_feature    complement(21122..21138)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.62"
                     /tool="antismash"
ORIGIN
        1 gaggacgccg tcgtcgccca cctcgcctcc cgcgccctgc ccggcgtcga cgtggtgttc
       61 ctcgacaccg gctaccactt cccggagacc atcggcaccc gcgacgcggt cgaggccgtg
      121 atggacgtga acgtcatcac gctcaccccg cgccagagcg tcgccgagca ggacgccgag
      181 tacgggccga agctgcacga ccgcgacccc gacctgtgct gcgcgctgcg caaggtgaag
      241 ccgctggagg aggggctggc cggctaccag gcctgggcga ccgggctgcg ccgcgacgag
      301 tccaagaccc gggcgaacac gccggtcgtc ggctgggacg agaagcgggg caaggtgaag
      361 atctcgccca tcgccaagtg gtcacaggaa gatgtgcaaa cgtacgtcac cgagcacggc
      421 gtcctcacca acccgttgct gatggacggc tatgcctccg tgggctgcgc gccctgcacc
      481 cgtcgtgtgc tggagggcga ggacgcccgc gccggacgct gggcgggccg ctccaagacc
      541 gagtgtggac tgcacggctg acatgacgac caccaccgga ccgacgccgt cgggaccatc
      601 gacatccagg gagaaccacg tgacgaccgg agccaccgtc tggctcacgg ggctgcccag
      661 cgccggcaag accaccatcg cccgcgcgct ggccgaccgc ctgcgtgagg agggccggcg
      721 cgtcgaactg ctcgacggcg acgagatccg cgagttcctc tcggcgggcc tcggcttcga
      781 ccgcgcggac cggcacacca acgtgcagcg catcggcttc gtcgccgaac tgctcgcccg
      841 caacggcgtc acggcgctgg ttccggtgat cgcgccgtac gcggacagcc gcgacgcggt
      901 gcgcgagcgc cacggggcga acggcacggc gtacgtcgag gtgcacgtgg ccacgccggt
      961 cgaggtgtgc tcggtgcgcg acgtgaaggg cctgtacgcc aagcaggccg cgggcgagct
     1021 gacggggctc accggggtgg acgacccgta cgaggagccc gtcaagcccg acctgcgcat
     1081 cgagtcgcag gaccagaccg tccaggagtc cgccgcggcg gtccacgccc tgctcaccga
     1141 aaggggactg gcatgacgac gaccgtcgca gcggcgcggg agggtacggc gggcccgtac
     1201 gccctctccc acctcgacgc cctcgaatcg gaggccgtgc acatcttccg cgaggtggcg
     1261 ggcgagttcg agcggccggt gatcctcttc tccggcggca aggactcgat cctgatgctg
     1321 cacctggcgc tgaaggcgtt cgccccggcg gccgtgccgt tctccctgct gcacgtggac
     1381 accgggcaca acttccccga ggtcctggac taccgcgacc gcacggtcga gcggcacggg
     1441 ctgcgcctgc acgtcgcctc cgtgcaggac tacatcgacc gcggggtgct caaggagcgc
     1501 ccggacggca cccgcaaccc cctccagacg ctgccgctga ccgagaagat ccaggcggag
     1561 aagttcgacg cggtcttcgg cggcgggcgc cgcgacgagg agaaggcccg tgccaaggag
     1621 cgggtgttct cgctgcggga cgagttctcc cagtgggacc cgcgccgcca gcgccccgag
     1681 ctgtggaacc tgtacaacgg ccggcacgcc cccggcgagc acgtccgcgt cttcccgctc
     1741 tccaactgga ccgagctgga cgtgtggcag tacatcgccc gcgagggcat cgagctgccg
     1801 cagatctact acgcccacga gcgcgaggtc ttcgcccgct ccggcatgtg gctgacggcc
     1861 ggtgagtggg gcggccccaa ggacggcgag cggaccgaga agcgacgcgt gcgctaccgc
     1921 accgtcggcg acatgtcctg caccggcgcc gtcgactccg acgccgacag catcgagaag
     1981 gtcatcgccg agatcgccgt cacccggctc accgaacgcg gcgccacccg cgctgacgac
     2041 aagatgtccg aggccgcgat ggaagaccgc aagcgcgagg ggtacttcta gacatgacca
     2101 gcaccactga acccgtcgag ccgctgtcgg tctggcagct gtcggagacg accctgctgc
     2161 ggttcgccac cgccggctcg gtcgacgacg gcaagtccac gctggtcggc cggctgctgc
     2221 acgactccaa gtcggtcctc accgaccagc tggaggccgt cgagcgggcc tccgcgagcc
     2281 gcggccagga cgtcccggac ctcgcgctgc tcaccgacgg cctcagggcc gagcgcgagc
     2341 agggcatcac catcgacgtg gcctaccgct acttcgccac cccgcgccgc cggttcatcc
     2401 tggccgacac accgggccac gtgcagtaca cccggaacat ggtcaccggc gcctccacgg
     2461 ccgagctgac ggtcatcctg gtcgacgccc gcaacggcgt cgtcgagcag acccgccggc
     2521 acgccgcgat cgccgccctg ctgcgcgtcc cgcacgtcgt cctcgccgtc aacaagatgg
     2581 acctggtcga ctaccgggag tccgtgttcg cggccatcgc cgaggagttc acggcgtacg
     2641 ccaccgagct gggcgtcccg gaggtcaccg cgatccccat ctccgccctg gcgggcgaca
     2701 acgtggtgga ggcgtcggcg gtcatggact ggtacggcgg cccgaccgtg ctggaacacc
     2761 tggagaccgt gccggtcagc cacgacctgg cgcactgcca cgcccggctg cccgtgcagt
     2821 acgtgatccg gccgcagacc gccgagcacc ccgactaccg cggctacgcg ggccagatcg
     2881 ccgccggcac cttccgggtg ggcgacgagg tcaccgtgct gccctcgggc cgcacctcga
     2941 aggtgtccgc catcgacgtg ctcggcgagc ccgtcgacgc cgcctggacc ccgcagtcgg
     3001 tgacgctgct gctcgaggac gacatcgacg tctcgcgcgg cgacctgatc gtgcccagcg
     3061 aggacgcccc ggccaccagc caggacgtcg aggccaccgt ctgccacgtc gccgacgcgc
     3121 cgctcaccgt gggccaccgg gtgctcctca agcacggcac ccgcaccgtc aaggcgatcg
     3181 tcaaggacat cccggcccgg ctcacgctgg acgacctgtc gctgcacccg caccccgggc
     3241 agctggtcgc caacgacatc ggccgcgtca aggtccgcac cgccgagccg ctgcccgccg
     3301 actcctacgc cgactcgcgg cgcaccggct cgttcatcct gatcgacccc agcgacggca
     3361 ccacgctcac cgccggcatg gtcggcgagt ccttcgccgc gccggagccg gtcaaggacg
     3421 cggccgacgc cgacgggtgg gacttctgag catgtcctcc cccgacttct actccacgtt
     3481 cgccaaggag ggcggccgcg tcggcagcgg cgccctgggc agcgggcagg gcggagtggc
     3541 gcgatgtgtg cgctgacgta cgcgcaccgc tcgcgcgccc tcaccccccg cagccgaaga
     3601 cctgccgacc tcccggccac gccctgaccc ctcggaccca ccgacaggcg tgcgtgccgg
     3661 accaacgaga ggaacacctc ccgtgcctgc caccaccgcc ctgcgccgca cgctggcggt
     3721 catagccgcc cttcccctgc tcaccctggc cgcctgcggc tacggctcgc aggcgaagga
     3781 cgacgacacc gccaaggtcg ccgagggcgc cgagaagatc gacggtctcg actccgtccg
     3841 gatcggctac ttcggcaaca tcacgcacgc caccccgctg gtcgccaacc agaagggctt
     3901 cttccagaag gcgctgggcg cgaccgaggc caagtacgcg gtcttcaacg cggggccgtc
     3961 cgagatcgag gcgctgaact ccggctccat cgacatcggc tggatcggcc cgtccccggc
     4021 ggtcaacggc tacgccaagt ccgacggcaa gaacctgcgc atcatcggcg gttcggcctc
     4081 gggcggcgtg aagctcgtgg tgaacccgga caggatcaag tccctgaagg acgtcaaggg
     4141 caagcgcatc gccaccccgc agctgggcaa cacgcaggac gtggcgttcc tcaactggat
     4201 cgccgagcag ggctggaagg tcgacgcgca gagcggcaag ggcgacgtga cggtcgtccg
     4261 cagcgacaac aaggtcaccc cggacgccta caagaccggt tccctggacg gcgcctgggt
     4321 gcccgagccc accgcgtcca agctggtcgc cgagggcggc aaggtgctcc tggacgagtc
     4381 cacgctgtgg cccgacaaga agttcgtgat cacgaacatc atcgtgtcgc agaagttcct
     4441 cgaggagcac ccgaaggcgg tcgaagccgt cctgaaggcg tcggtcgaca ccaacgagtg
     4501 gatcacggcc cacccggacg aggcgaagac cgcggcgaac gcgcagctgg cgaaggactc
     4561 cggcaaggca ctgcccgccg acgtgctgga cccggcctgg gagtcgatca ggctcaccga
     4621 cgacccgctg gcctccaccc tcgacgccca ggcggagcac gccgtgaagg ccggtctgct
     4681 ggaccggccc gacctgaacg gcatctacga cctgacgctg ctgaacaagg tcctcaaggc
     4741 caagggcaag cccgcggtcg acgacgccgg gctcggcgtc gagtaaagcc cggatccgac
     4801 cacccaggag gtgacgacca tggccacgac cacgaccctc gccaaggccg ccgacggcac
     4861 cgagtcggcc gactacgcgg cccgcatcga gcacgtctcg aagtccttcg cgggccccgc
     4921 cgggcagcag ctcgtcctgg acgacatcac cctcgatgtc gcgcccggcg agttcgtcac
     4981 cctcctggga gcctccggct gcggcaagtc cacgctgctg aacctggtgg cgggcctgga
     5041 caggcccagc gcgggcggca tcagcacgga cgggcggccg gccctgatgt tccaggagca
     5101 cgccctgttc ccgtggctga ccgcgggcaa gaacatcgaa ctggccctgc ggctgcgggg
     5161 cgtgcccaag gccgagcgcc gcgacaaggc ggaggagctg ctcgaactcg tccgtctgaa
     5221 gggcgcgtac ggcaagcggg tgcacgagct gtcgggcggt atgcgccagc gggtcgcgat
     5281 ggcccgggcg ctcgcccagg agagcaagct gctgctgatg gacgagccgt tcgcggcgct
     5341 ggacgccatc acgcgggacg tgctgcacga cgagctgacc cgcatctggc gcgagacgca
     5401 ggtgtccgtg ctgttcgtga cgcacaacgt ccgcgaggcc gtgcggctgg ccgagcgcgt
     5461 ggtgctgctg tcctcccgtc ccgggcgcat cgcgcgcgag tggacggtgg gcatcccgca
     5521 gccgcgccgt atcgaggaca ccgccgtggc ggagctgtcc gtcgagatca ccgaagaact
     5581 gcgtggggag atccgccgac atggccagca ctgacacgac gcgtcccgcc cgggacccgg
     5641 gcgcgaagga cggcggcgac ctcgccggtc tggaggcggg cctggacgca ctggagtcgg
     5701 tgcagcaggg gcgcacaccg ctgcggcaga ccctggtcga gaaggtcctg ccgcccaccg
     5761 tcgcggtcct gctggtgctg gcggtctggc aggcactggt ctccttcaag atcgtcgacg
     5821 atccgaccaa gctgcccgcc ccgtccgacg tgtgggacgt gctgcaccag gcctggctcc
     5881 agggtgaact gctcggctac atctggacca gcgtctcgcg cggtctgctc ggcttctgct
     5941 tcgcgctgat catcggcacc ccgctggggc tgctggtggc gcgggtgaag ttcgtgcggg
     6001 cggcgatcgg cccgatcctg tccggcctcc agtcgctgcc gtcggtggcc tgggtgccgc
     6061 cggccgtgat ctggctgggt ctgaacaact cgatgatgta cgccgtcatc ctgctcggcg
     6121 cggtgccctc catcgccaac ggcctggtgt ccggcgtcga ccaggtctcc ccgatcttcc
     6181 tgcgggcggg gcgcaccctg ggcgcgacgg gcctgaaggg cacctggcac atcgtgctgc
     6241 cggccgcgct gcccggctac gtcgccggtc tcaagcaggg ctgggccttc tcctggcgct
     6301 cgctgatggc cgccgagatc atcgcctcct tccccgacct gggcgtcggc ctcgggcagt
     6361 tgctggagaa cggccgcaac gccagcgaca tggccatggt cttcgaagcc atcctgctca
     6421 tcctggtcgt cggcatcgcc atcgacctgc tgatcttcag cccgctggag cgctgggtgc
     6481 tgcgcagccg cggtctgctg gtgaagggct gaggcacacc atgtccgcac cggcccgccc
     6541 cgtcctcctg gtcgtcgccc acggcagccg cgacccgcgg cacgcccagg ccgtgcacgc
     6601 cctggtccgc cgggtgcggg cgctgcgtcc ggacgtacgg gtggagaccg gcttcctgga
     6661 cttcaacgtc ccctcggtac ggggcgtgct ggagtccctg gagacggagg gcgtgcggga
     6721 cgtggtcgcc ctcccgctgc tgctgacccg cgccttccac gccaaggcgg acatccccgc
     6781 ggtcctggcg gcggcaccgc cgcggctcag gatccggcag gcggaggtgc tcggtccctc
     6841 tcccctgctc ctgtcggcgc tggagcggcg cctgtacgag gcgggtctca cacccgccga
     6901 caagtcctcg accggggtcg tgctggcctc ggcggggtcc tccgacccgg aggcgatcgc
     6961 agtgatcgct gatatcgcgc gggagtggcg gcacaccggt tggtgcgccg tgcggcctgc
     7021 gttcgcctcc gcatcccttc cgcgcaccga ggacgcggta cggcggctgc gcgcgctggg
     7081 ctgtgcgcgg gtcgccgtcg ccccgtacgt cctggcgccc gggttcctgc cggaccggat
     7141 cgcgcggggc gcggccgagg cggacgtact ggcggacgtg ctgggccccg caccggaggt
     7201 ggcgcgggtc ctgctggagc ggtacgacgc ggcgcggatg ccggtggcgc tggcggtcgg
     7261 ggcctgaggg gacgaggacg acgacgcgtc agggccgcgt cagctccacg agtttggcga
     7321 ccgtgttcca gttacggctg gtggcgatca ggcccttggt gacccggggc ctggcgagag
     7381 cctcggcgag cttggagcgg cccagcccgt ccggtgcgta gaggtagagg gcgcggtcgc
     7441 cgaggcggaa ctcctcgggg cggaaggccg gtgcgtcgat cgccgcgaaa cgctccgcgt
     7501 cgaccggggc ggagaagtag gtgacgtgca gctgcctggc ctccagctcg gcggcgggga
     7561 aggggcacgc ctcgacgatc cccttcaggt aggcgtggtc gcgcacgagc acgtccaccg
     7621 ggaagccgaa ccgcccctcg accgccgtgg ccaactccgc ggccagcgac tcctcgtcgc
     7681 cgtgatcgga ggcgaagacg gcctgtccgc tctgtagatg ggtgcgtacc gcgtcgtggc
     7741 cgagggaggt cagcagggcg cgcaggtcgg ccatcgggac cttccggccg ccgcccacgt
     7801 tgatcccgcg gagcagtgcc gcgtacatcg tcgtcatccg cacaccatag aacggccgtc
     7861 gtgccccgtg ggggtgggca cgacggccgg gtccgcaccg ggcggacgtg cgcgccactc
     7921 tctccgatgc ggtgtgcggg gttcaaccac ttcccgcacc tgtgacttaa tcaacaacgt
     7981 ttcagtacgg ccccgccggg cttccgcgcc ctccccggcc gtcgcgccgc gtgtgggccg
     8041 gccgtgacac ctggtggacc actgggtgga gagcggcttc gcggggcagg tcaccggctg
     8101 ccccgcccgc ggtcagtact ccctgatgaa gcagtcggag acgtacccct cgactccggt
     8161 gcggttgttg tggacgtacg tccagtggtc cttgacgctg ccgtccgggc agggcaccgc
     8221 ttccgcgttg gcctgtccgc ccatccaggt gtacccgtcg ccggggttgc cgtgcccccg
     8281 ggcggacgag gtggtgctgt agctctcgtg gatcttcacg ccggtcgcgg tgaagtcgcc
     8341 ctgacgtggc gcggcggtgg ccggggagga gaacaccgtc cccaggagtg tcagcgtcag
     8401 tacggcggcg gtcgtcatgg gggcggtctt cgcggtggtg tgccgggtgt tcatggaatg
     8461 ccttcctgtc cgagtctgtg cggtcggtgc ggtcggcagt gcggtcggtg cggccgttgc
     8521 ccgtctgtgc cgtcggtctc tcttcggccc ctcaccagtg gtcggcgcgt ccttcgtctt
     8581 caggagcctc accggtcgtg acgtccgtcc ccggccctgc gggctcgggt tccagtcgcg
     8641 cgcggaagtg gcgcaggatc ggggcgtctt cgacgacgcg gtaccccggc accctgtcct
     8701 tgtccttcac caccgcttcc agggtctgtc cgacgtggtc cagatggctc cgggtgtacg
     8761 tccggcgcgg aagcgcgagg cgcagcagct cgtacggggc ggtggtgacc gggtccccgt
     8821 tgccgtcctc cttgccgagg tagagggagc ccagttccac cgaacggata ccgccctcca
     8881 ggtagagcgc gcaggcgagt gcgtgccccg ggaagcggtg cggggcgatg tgcgggagga
     8941 ggtggcccgc gtcgaggtag agggcgtgca gaccgggggg ttcgaccagg cggacgcccg
     9001 cgccgcggca cagccccgcg agatgggcgg ccgcttcggc ccgggagcgg aggtagtggg
     9061 ggtccagggc ctcggtcagg ccctggacga tcatctccag gtcccgtccg gcgagtccgc
     9121 cgtaggtcgg gaagccctcc gtggcgatga ggatcggctc gcaccggcgg gccagtgcct
     9181 cgtcccgcag accgaggaag ccgccgatgt ggacgatgcc gtccttcttg gcgctcatca
     9241 ggcagccgtc ggcgaggcgg aacgcctcct tggcgacgtc cgtcggactg cggccgccgt
     9301 acccggactc gcactgggtg accaggtagg cgttctcggc gaagcgggcg gcgtccagga
     9361 agagcgggac gccgtgctcc cggcagaggg cggcggcgcg ggccaggttg tccatggaca
     9421 cgggctggcc gccctcgccg ttgttggtga gcgtcatgat caccagggcg atgcgggcgg
     9481 cgtccgggcc gcgcagttca gccgccaggc cgtccaggtc gatgtcgccc ttgaacggct
     9541 cggggctgtg caggttccgc gcccgcgcac agggcaggtc acgggcctgg cagccgctca
     9601 gctccacgtt ggcgcgcgtg gtgtcgaagt gggtgttgct gagggtgatc cggccgggga
     9661 ccagcagcgc ggagaacagg acgcgctccg cggcccggcc ctggtgcacc ggcaggacgt
     9721 gcgggtagga ggtcagttcc gtgacggccg cacggaagcg gtggaaggaa cgcgagccgg
     9781 cgtacgactc gtccccggcc gcggcggccg cccactgggc cgccgacaga gcaccggtgc
     9841 cggagtccgt cagcaggtcg atcgtcactt cctcggcgcg cagtccgaac aggttgtacc
     9901 cgacgcggtc cagggccctg gcgcgctgtg cgcgggtggt cgtgggaatc ggttcgacgg
     9961 ccttgatgcg gtacggctcc atggtgctgc tctgctttcc tcagtgcggc gggtggacgg
    10021 cgtatgcctc gggtgagaga tagaccgtca cgcgcggcgg gccgccggtg ctccgggcga
    10081 gcgagacgta ggagatcagc cccactccgt cggacaggtg acgggacgtc atcgcggcga
    10141 gtgccttgtc cagcagggcg acgtccccgc cgcgcgcgcc cagtacggcg gcggcccggt
    10201 cgcgggcgac acggtcgtcg cgggcgtagt cgcggaccgg gacgtgcagg gtgtgtccgc
    10261 tgggacgttc ccggtcccgg cgggtgaagg acaggcagga gaccaggggc agaccgtcga
    10321 aacgacgggt gccaccaccg atcgtgcggc agaagtcccc cgcacgccga gggtccgcgc
    10381 cgggcagcag cccggccgcg gcttccgctt cctcgacgga gaaaccctga tgggcgatgt
    10441 acagcttcac ccgtggttcc cgccagtggc cgaggtccag tgcgaagaac aacagcctgc
    10501 cccggtccgg gcaccaggac gcggcccgcg ccgtcagcgc cggccatgcc gaccggaacc
    10561 cgaagcgggt cagcgcctct tcgacgacct cgccggcgcg gtcccggccg tgcgcctcgg
    10621 ggttgaggta gaccttcacg ccgggcggcc ccgtccgacg caggtccatg gcgcaccaga
    10681 gcgagaaggg gccgcgggcc gccgcgggaa ggaagaggtc cgtgacccgg gcgacgggct
    10741 ccgcgtcgac gtcccagcac ctcgccatcc ggtccagggc ccgcagcccc gcccggccgc
    10801 cgtcggcgaa ggtcccggcg ccgcagcccg gctcgaccag cacccgtacc gtcggcgcac
    10861 cgtcggcggc gaacgacacg gacagctcgg ccggcgagtg gtcgtcgctg acgaaggacg
    10921 gtgagagcgg cccggcaccc agcggacgtc ctgccgccgg gcccagcagc ccgggcagca
    10981 gccgctccgc gtcccgcgcc cagcggcagg tcacgtccgc ggcggcgagc agtcgccgaa
    11041 gctgcccggc cagatgctcc cgcagcgtcg gcgcggcggg aacggcgccc gtgctccggc
    11101 gcgggggaag ggcatagccc gaaggggcgg gcgggttcat ggcggcctcc ggggtgcggc
    11161 gcgggaagaa gtccacgatc tccgccgcgg ccgtcgcccc ggtcgcgcgc cggtcactcg
    11221 gcgatctcag gtcattacgg caggtatccg atcggtcacg caccgttgta ctctgtgggg
    11281 tgtccgggcg agggcccgac gggggaacag tgagaagcac atacgagttc gggatcctcg
    11341 gaccgctgct ggtccgtcgg tccggcgcac cggtccacgt caacgccgcc aagctgcgga
    11401 tgctgttggc gtccctgctg gtcgaggccg accgggtggt gaccgtggac gccctggtcc
    11461 accgcctgtg gggcgacgcg cctccgctcc gcgcccgcaa cacccttcag aactacgtgc
    11521 tgcgtctgcg ccgcgcgctg ggcagccccg cggacaccgg cccggtacgg acccgtcccc
    11581 acggctacct gatcgagacc gacccgcaga cgctggacgt gcgccgcttc acctcgctcg
    11641 tccggctcgg gcggaccgcg ctggagcaga acacggccga gcgggcggcg gcgctgctgc
    11701 ggcaggcgct ggagctgtgg cgcggggacc cgctgtgcga cctgccgggt gacgcctttc
    11761 ccgagctgcg gctgacgctt cgggaacagc acctggccgc gctcgagctg cgcatcgacg
    11821 cggacctggc ggcgggccgc tccgcggacg tcctgccgga gctgcgggcg ctggtcgaag
    11881 cccatccgct gcgtgagcac ttctgggccc agcgcatgct ggcgctctac cgctgtgagc
    11941 gacagagcga ggccctcgag tgctaccgca cggtcaccgc gctgctcacc gaggagctgg
    12001 gagtcacccc cggtcccgcg ctgcgggaca tgcacgcgcg gctcctcgcg gcagctcccg
    12061 acctcgggcg gccaccgggc ggcgcggcgg ccgccgcgtc gccgaccgct cccggccggc
    12121 ccgccctgcc cgtcgagacg accggcttca tcggccgcga ggcgcaactg gcccaggtcc
    12181 gcgccctgct gtcgacggcc cggctggtca ctctcaccgg tgtgggcggc gtgggcaaga
    12241 cacggctggc gctgcggtcg gcggcacaac tcgccgcctc gtacgcggac ggtgtccatc
    12301 tcgccgacct cgcggcgctc acctcgccgg acctgctcga ccgcgccgtc gccgaagccc
    12361 tggggctgcg cgaccagtcc gcgagaccgc ccgcgcaggc cctcgtggac gccctgcgcg
    12421 accggcagct gctcctcctc ctggacaact gcgaacacgt cgcggacgcc gtcgcgggcc
    12481 tggtcctgcg gttgctgcgg gccgcaccgg gactgaccgt cctcgccacc agccggcacc
    12541 gcctgggggt acccggcgag cacatcctga ccgtgccctg cctcacgctg ccggagccgg
    12601 acgccgggtg cgacgcccgg cagcccccgg agcgttccga atccgcgcgc ctcctggtgc
    12661 agcgcgccgc cgcgtccgct ccggcgttcg ccatcaccgc ccgcaaccgc gccgccgtcg
    12721 cccagctgtg ccggcgcctc gacggcatcc ccctcgccat cgaactcgcg gcggtacggc
    12781 tcggcgcgat gacggccgag gagatgctgg aacgcctcga cgaccgcttc cgtgtgctct
    12841 gcctccccga catgccgggc accgagacgc gctaccagca cactctgcgc ggtgtcatcg
    12901 actggagcca cacgctgtgc accccgcgcg aacgcctgct gtgggcgcgc ctgtcggtgt
    12961 tcagcggcgg cttcgacctg tccgccgccg aagccgtgtg cgcgggtgag ggcgtcgagc
    13021 gggaagagat cctggacctg ctcgccgcgc tggtgaacaa gtccctggtc gcggtcgaca
    13081 gcaccggccc gcgcgcccgg tacggcatgc tggagaccat ccgccagtac ggtctcgagc
    13141 ggctgggcga gctgacccgg cagaccgggc tgcgcatccg gcacggcgcc cactaccggg
    13201 ccatgaccct gcgcgcgggc gccgagtggt gcggccccga cgaggtcgac tggctgctgc
    13261 ggctgcgcga ggagctgccc aatctgcgca ccgcgctgga cttctgcgcc acccggcccg
    13321 agcacgtcgg caccgcggtc gccatcgccg tcgacctcgc ccggacccgc tgctggttct
    13381 tcagcagtgt gctcggcgag ggccgctact ggctggagcg cctcctcgcc gccgcgcctg
    13441 ccctgccgcc cgacctgacg gtgggcgcgc tggccatgaa ggtgtggatc gcgctgtgcc
    13501 agggggacaa tccggccgcc gagaggttcc tggccgagtg ccgcgcacag gccgcgggct
    13561 ccgacggccc ggcggtggcc ccgttcacct tcatcgaggg cgcccacgcc ctgctcgtcg
    13621 acggcacctc ggcgtcgatc cccctgctgg ccgccgcgcg ggagcagttc ctgcgggacg
    13681 ggcggcgcgg tgacgcccac atggccacca tgatgtgggc catggccgag gccttcctcg
    13741 gcgacccggt ctcggcccgt gcggccgccg gggagtacac cgccgaggcc gaggccggcc
    13801 gggcgccatg ggcccgcacc tgggcccgct ggtgcgcggg cctggtcgag ctgcgccacg
    13861 gcgatccggc cgcggccctg gccccgctgc gcgacgccct cgcccggcag aactccttcg
    13921 gcgacaactg gggccccgtc tggggggtgg agaccctggc ctgggcggtc gccgagacgg
    13981 accggtacac ggatgccgcc cggctcctcg gtgcggcgca ccggctgcgg caggacaccg
    14041 gcgtcgcgct gaccggcctg cgtccgttcc acgacgccca tgccgccgcc gagcgccggg
    14101 tccgtgcggc cctgaccacc caggagtacg cgcgggcccg ggcgtacggc gccgcccaga
    14161 acagcgtgct cctcgcgctg cgcatcagtg cggagccggg cggggacccg cgcgccgagg
    14221 aggtcacgga tcccggtgcc tgaccggccg gcccggcgcg gccggcggtc tgcgggcgcg
    14281 gaccccggta gatgtaaggg accggtgtcc tcctcagcgg tgagttcggc ggtacggagg
    14341 gatgagggcg gggccgcggc acgtcaccaa ggagcacgac gcggcgtcct tacgcgggcc
    14401 ataccttcga aacgcgaggt ggcggcaggg ggccggcacc gcacacgagg gggcaggccg
    14461 gtcatgcgga accgagagac acgggtgcgg ggcatagccg cccgggcggg cggctggagt
    14521 gcccggcacc gatgggccgc cgtcgggatc tgggtgttgt tcgtggtcct ggcgatgggg
    14581 ctcggttcgg ccgccggccg ggtcgacgtc aaggacagcg accagatggg cggcgagacc
    14641 cgcaccgccg cgcggatcgt cgaggacgcc ggcatcgacg aaccggccgg tgagacggtc
    14701 ctgatccagg cgaagtccgg tgatctgttg gccacggacg ccgagttccg ggccgcggtc
    14761 ggcgcggtcg tcacggcggt ggaggccacc gggaaggtca ccggcgtgac ctcgccgtac
    14821 gacacgaaga cgatctcgaa ggacaaccgc agcgcgctgg tgcagttcga catgcgcggc
    14881 gaggcggaca ccgcgggtga gcgggtcgag ccggtgctga aggcggtcga gggggtccag
    14941 aaggagcacg cgtcgctgcg gatcgaggag atcggcggcg ccagcatgat gaagacgttc
    15001 gacgacgcgt tcggcgacga cttcaagaag gccgagtact cggcggtgcc ggtggccctc
    15061 ggcatcctgc tcgtcgcgtt cggcgcgctg gtggcggcgc tggttccggt ggcgctggcg
    15121 atcaccgcga tcatcgcgac gatggggctg atgggcctgg tcagccactt ccagccgatg
    15181 agcgagaccg cgaactccgt gatgctgctg gtcggtctgg ccgtcggcgt cgactactgc
    15241 ctgttctacc tgcgccggga gcgcgaggag cgcgccgccg gacgggacgc gcggacggcg
    15301 ctcaggatcg ccgccgccac cagtggccgg gcgatcgtcg tctccggtgt cacggtgtgc
    15361 gtggcgatgg cgggcatgct gttcaccggc atcgccgagt tcgaggcgat gggcctggcc
    15421 tcgctgatgg tggtcgcggt cgccatggtc ggctcggtga cggtccttcc ggcgctgctg
    15481 tccctgctgg gcgagcgggt ggagaagggc cgcgtgccgt tcctgcgccg gcgccggccg
    15541 agcggtggca cgggtgaggg cagccggttc tggacggccg tgctcaagcg cgtcctggcc
    15601 aggcccctgc tggccgccgt ggtcgccgtc ggcgcgctgc tggccgtcgc cgcgcccgct
    15661 ctcggcatga agacgcagaa cctcacgctg gaccaggagt tcggcgactc gctgcccatc
    15721 gtgcagacct acaaccgggt caacgaggcc tttcccggcg gttccgaccc ggccgaggtg
    15781 gtcgtgaagg ccgacgacat caacgcgccc gaggtgcggg cggcgctcgc cgacttccgg
    15841 gagcgggcca tcagttcggg ggcctcgcgc gggccggtgg acatcacgac gcacgacgag
    15901 cagaacgtcg cgctggtgta cgtcccgctg gtcggcggct ccgaccagga caaggcgggc
    15961 gagagcctgg acaagctgcg cgacgacgta cggcccgcga cgctggggaa ggtcgacggc
    16021 gtcgaggcgc cgatcaccgg tcaggtggcg ggcaacaagg acttcaacga ccagctcgtg
    16081 ggatcggtcc tgccggtctt cgccttcgtc gtggtcttcg ccttcctgct gatgctgctg
    16141 tccttccgct cgctgacgat cgccctcacc tcgatcgtgc tcaacctgct gtcggtgggc
    16201 gcggcgtacg gcatcctggt cgccgtcttc cagcacggct ggggcgcctc gctggtgggt
    16261 gcggagggcg tgggcgccat catcacgtgg ctgccgctgt tcctcttcgt gatcctgttc
    16321 ggcctgtcga tggactacca cgtgttcgtg gtctcccgga tccgcgaggc ccggctgcgc
    16381 gggcgttcca cccgggacgc gatccagcac ggcgtggtca ccaccgcggg ggtggtcacc
    16441 agcgccgccg tcatcatggt cgcggtgttc gccatcttcg gcacgctgtc catgcagtcg
    16501 atgaagcaga tgggcgtggg cctggcggcg gcggtgctga tcgacgcgac gatcatccgg
    16561 ggtgtgctgc tgccggccgt gatgtcgctg ctcggtgagc gcaactggta tctgccgaag
    16621 tggctgcacc ggctgccgga cctgacccac gacgagtcgc ccgaggcgat cgcgtcgccg
    16681 gagcgggacg gcgagagcga gcgcggggag cgggggaagc cggtcggggt ctgaccggcg
    16741 cgccaccacg accgcagggc ctgccggttc cgggggaacc ggcaggccct gacggcgtgc
    16801 ggcggggaat cagccgcgcg cggcggccag ttcggcctcg atgaggtcgg cggcccgccg
    16861 ggtgccgccc tcctgggcca tctgcgcctg gatctccttg agccgccgcg ccgcctccgg
    16921 gtcggcgacc agggcaaggg cggcggtgcg cagcgcctcg gcggtggcct cctcggtcgg
    16981 gagcgtgcgg gcgacgccga ggccctggag catgtcggcg ttgccgaact ggtccgcggc
    17041 ctgcggtacg gcgatcatcg gcgtggccgt cgccaggccc tcctggctgc cgccggcgcc
    17101 cgcgtgggtg acgaacaggt cggcctgctg gaggatcgcc aactgcggca cccaggtgcg
    17161 cacttccacg gtgtccggta cgtcgcccag ctcggccggg tcgatgtgcc ggcccacctg
    17221 gagcacggtg tgccagccgg gcagctcgcc gaaggcccgc acgcactccc ggtagaacgc
    17281 gggctgcttg gtgaaggcgg acccgaggga gacgaggacg accttctcgg cgccctcggg
    17341 acgggtccag tcgccctcgg cggcgcggtc cccctggcag gcgccgacga aggtgtacgt
    17401 cttctcgtcc acccggtcgg cgttgggctg gagggccttg gggatcagca ccagggagcg
    17461 gtcggggcgg ccgacgaagg ggtcggggtg gtcggtgatc ccgttctcct cgagccaggc
    17521 gtggaagcgg gcgtagtacg cctgcccgcg ctcggtcttc agcggctcct cccacatggg
    17581 ctcgccgacc tcctgctcgt acccctccca ggcgaccatg cagggcgaca gggagatcac
    17641 gggcacgtcc cagcgacggc cgagcacgcg ggcggtgtag gagccgatgt cgtgcaggac
    17701 caggtccggc tcgtccccct cgtacgcctc ggcgagctgc gggagtgcct ggatggcgtc
    17761 gtcgaggaag ggctccacgt tgtccagcag ggtgctcccc cacgcctccg ggtcggcgtc
    17821 ggggccgggc agcgtgctgt tccagagctt gggttcggcg ccagcctcgg cgaccttgtc
    17881 cgcgagcagg ggcgggatcg cgtaggtcac ccggtgtcct cgcgcgacga gctcgcggat
    17941 cacctccagg ctggggttca cgtggccgtg ggcggcgatg gagaacatgg cgatgtgcgc
    18001 ggggcgactg gtcatgcgac gaccgtacgc gagacgagac gtctcgtgca actgctttcg
    18061 cttcatgccg tcagctcctc gtgcagccgc agccaccggt cgggtgcgac ctcgccgacg
    18121 aggacaccgg gatcgagccg cgcggcccgg aacgccgcgt ccacccggcg ccgcgggtgg
    18181 gtccgccgca gggacgcgtg cagcgagccg ccgacgcccg agaagcccag ctcgaccagg
    18241 tcggaccagg tgcggcgggc gccggcgccg gtgagcagcg gggtacggcg ccgtgcgatg
    18301 cggaggatgc cggcgtcgac gcgcggcgcc ggccggaagc ggtgccggcc cacccggccc
    18361 agcagccgcc actcgtggcg cggccaggtc aggaccgtga ggagggtcca gcggccgtag
    18421 tcgccggtgc gtttgcgggc gtactcgagc tgggtgagga gggtggcgtc ggtgaggcct
    18481 ggggcggcca ggcaccagtc gacgatgtcg gcggtgcgtg agaagggcac gttcccggcg
    18541 acggcgaacg gcgtgcgcgg gggccgggcg gcgaggaagt caccggcgac cacgtggacg
    18601 tgcggggtgc gggcgaaacg ggcgcggagc ccggggacga gccgggggtc gatctcgtag
    18661 gcgtgcagct cgcggctgcg gcgggcgagc ggctcggtga gggcgccgtc gcccgcgccc
    18721 acctcgagca gcaggggcgg ctgccgtcca tcgggggcgg cgaggcgcgc gacgtgtgcg
    18781 gcggtggcgc ggtcggcgag gaagttctgc gagagcgtgc gggcacgcgg ggtggggcgg
    18841 gccatggcct gcggtccttg tcttccgtga caggagggga aaagggcagc cgaaggccct
    18901 gaccggaaga cgaaggcaaa agggaatgcg gaggctcagc cccgccgcgc gcgtcggagg
    18961 cgtggaacgc gtcgggcgcg tcagcggcgg ggggaccccg ggccggtcag ggctccgggg
    19021 ccgcgacgca tcctgatgga gtacgtgcag ccccggccga gaccggagtt gatgatcgcg
    19081 ttgaaagctg ccacggaggc gacgctaggc gggcgggtgc ccggcgggca aaccgttttc
    19141 gcgcgacggc cgtcagcgcg tggcgggcac gcgacaggcc tcagcacgcg acggcgcgca
    19201 acaggctcag cgctgggcgg ccgtccgcgc gtggcggtcc tcagcgcagg gcggccgtcc
    19261 gcgggtggcg gccctcagcg ctggtagcgg gcgagcacca ggttcccgtc ctcctccagt
    19321 ctgtggcgca gttcgtcggc gccgatcgct ccgctgtagt actcctggag cgccggcgtc
    19381 gccaccttgt ccttccactc ggcgtagccc cgcacggact gcgccggcgc cgagcgcagg
    19441 tgggcggcga gcgcggtgcc ggtggcccag ccgtgctcgg ccgtgtgcag ggcggggtcc
    19501 ttcagggcct gctccccggt gggcagcatc cagtcgccga gcgcgaggcg caccatgttg
    19561 tccggctgga ggaggaagtc gacgaacgcg gcggcctcct tcctgtgcgg gctgtcctcg
    19621 gcgacggaca gggtctgcgg gctgaccccc tgggcgagcc cgtcggcgcc ggccggggcg
    19681 ggcagcaccc gccagtcgaa gccctcgggt gcctgctgct cgatctgctg gcggtaggag
    19741 aagccgagcg gcaccatcgc gtacttgccc gcgaagaagc cgggcagggt gtcggagccg
    19801 ccgctgccca gggtggtcgg cgaggcgctg cggtcggtgt cgacctggtc gtggatggtg
    19861 cggggcacca cctggtcgcc ctcctcgaag cggacggtca ccctgccgtc ggcgccccgg
    19921 tggaacagct tgccgccggt ggacagggag aggttgagcg tggcggagac gggctccttg
    19981 agcggccagg ccaccccgta cgtgccgtcg ccgctcagct ccttcgtcac ctgccggaac
    20041 tcctcccagg tccaggggtg ttccggcgtc gggatccgga cgccggactt ctcgagcagg
    20101 gtggcgttgg cgatcagcac ccgcggttcc tggaggaagg gcacgccgta gacgccgtcg
    20161 ccgaaggtga ccgtctccca gctgtgccgc gggatgtccg acctcagccg cgcgggcagc
    20221 agttcgctga ggtcggcgag gtagccgccg taggcgaagt cggcgaggtc gtcggaggcg
    20281 tcgtggatga tgtcgggcgc ctcgccgccc tcgaaggagg tgagcagctg gtcgtggacg
    20341 ctgtcccagc tgccctggac gtactcgacg cgcacgtccg ggtgggtggc gttccactcc
    20401 cgtaccagtt ccctgttggc ctgcacggac tcgtcctgcc aggccaggga ctggaagcgc
    20461 agggtgatcc ggccgtcgtc cgccccgtcg ccgccgcccg agcagcccgc gagcagcagg
    20521 acggcacagg cgaacagggt gaggatcctc gtgggcgtgc gcgtcatcag ctcttcaccg
    20581 ccccggcgag catgccgccc gtgatccgcc gctggatgag ggcgaagacg agcagcgagg
    20641 gcagggtggc gaggaaggcc gccgcggcga gcggtccgag gtcggcgacg ccctcggcgc
    20701 cgatgaagtg ggtgaggatc acgggcaggg tctgtttctc cggggtcttc agcaggacca
    20761 gggcgaagaa gaactcgttc cacgcggtga tgaaggcgaa cagagccgtg gccacgatcc
    20821 ccggcgcgag cagcggcgcg gtcaccgaga ccagggtccg cagccgtccg gcgccgtcga
    20881 ccgcggccgc ctcctccagc tcgcgcggta cggcgcggac gtatccggcg agcatccaca
    20941 gcgcgaacgg cagcgaccag acgacgtaca ccatgacgag cccgggaacg gagttgatca
    21001 ggccgaggtt cttgaggacc aggaacagcg ggatgatcag caggacgaag gggaaggcct
    21061 ggctgaccac gacccacccg gtggccgcct tggcgagccg cccgcggcgg cgggccatga
    21121 cgtacgccat cggggtcgcg atcagcaccg cgatcacggc ggcgccgagc gcggcg
//
