LOCUS       NZ_KZ195574            22730 bp    DNA     linear   CON 06-SEP-2024
DEFINITION  Streptomyces sp. CS113 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ195574
VERSION     NZ_KZ195574.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS113
  ORGANISM  Streptomyces sp. CS113
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8695358)
  AUTHORS   Malmierca,M.G., Gonzalez-Montes,L., Perez-Victoria,I., Sialer,C.,
            Brana,A.F., Garcia Salcedo,R., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Searching for Glycosylated Natural Products in Actinomycetes and
            Identification of Novel Macrolactams and Angucyclines
  JOURNAL   Front Microbiol 9, 39 (2018)
   PUBMED   29441046
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8695358)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Searching for glycosylated natural products in actinomycetes
            isolated from leaf-cutting ants: activation of two silent clusters
            and identification of a novel macrolactam
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8695358)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAY-2017) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 78.17x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002188365.1-RS_2024_09_06
            Annotation Date                   :: 09/06/2024 02:31:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,790
            CDSs (total)                      :: 7,719
            Genes (coding)                    :: 7,614
            CDSs (with protein)               :: 7,614
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 1 (5S, 16S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 105
            CDSs (without protein)            :: 105
            Pseudo Genes (ambiguous residues) :: 0 of 105
            Pseudo Genes (frameshifted)       :: 35 of 105
            Pseudo Genes (incomplete)         :: 81 of 105
            Pseudo Genes (internal stop)      :: 4 of 105
            Pseudo Genes (multiple problems)  :: 15 of 105
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:56:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1313494
            Orig. end                         :: 1336224
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ195574.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Salas's laboratory, A.
            Microbiology, University of Oviedo, Spain.
FEATURES             Location/Qualifiers
     region          1..22730
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="8"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22730
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22730
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12730](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12730)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    1842..1855
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.82"
                     /tool="antismash"
     misc_feature    2833..2847
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     misc_feature    complement(4031..4044)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.1"
                     /tool="antismash"
     gene            complement(4059..4940)
                     /locus_tag="B9W62_RS05675"
                     /old_locus_tag="B9W62_05690"
     CDS             complement(4059..4940)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031104.1"
                     /locus_tag="B9W62_RS05675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05690"
                     /product="DUF4132 domain-containing protein"
                     /protein_id="WP_087805784.1"
                     /transl_table=11
                     /translation="MGWLAAGDTYEVALVEGRVVARSTAAAGTASEGKRERTLPAEIRD
                     RPEVVELQRFAEWLDRHAAECAAQVGTWMVSSLPVPTGLLARVWPDEAWQTALRDIVVV
                     GEAPDEVGFLRDADESDGLRVVNLDGETVRLNPRTVTMPHPVLLPDLEELRTFAAELGV
                     VQGVEQIHRATWTAPGAGEDGGTDVVTEFAGAEYRSWFHLSARATSLGYRISGSRIVDR
                     VRDAGRVFTASVGMSDPYTEEKAWTGGLSWSHGDGYRSLPLHEVGPVAYSEGMRMAAAL
                     HAGRTVPTDGAE"
     gene            5468..6076
                     /gene="ramR"
                     /locus_tag="B9W62_RS05680"
                     /old_locus_tag="B9W62_05695"
     CDS             5468..6076
                     /codon_start=1
                     /gene="ramR"
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031103.1"
                     /locus_tag="B9W62_RS05680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05695"
                     /product="two-component system response regulator RamR"
                     /protein_id="WP_160166096.1"
                     /transl_table=11
                     /translation="MGEMVRIAVVHDEKLLRSALVQLLRSDDTLDVTSHCLDADGPEPG
                     AALPADVCVVDGECLTGPEVAGAGRLRARYGDRLVVLATAKRPGVLRRAFDGGALGLVD
                     KNAPAHRLITAVHTVAQGERFLDETLTVALLKGAEMPLTTRELGVLALASQGAPIAEIA
                     ARLHLSRGTVRNYLATAVRKVGARNRVDAIRIVQSAGWT"
     gene            complement(6081..7916)
                     /locus_tag="B9W62_RS05685"
                     /old_locus_tag="B9W62_05700"
     CDS             complement(6081..7916)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972311.1"
                     /locus_tag="B9W62_RS05685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05700"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_087805787.1"
                     /transl_table=11
                     /translation="MTSAEAGALRRLAPPARRFLAHRKGVLVRLALWSLAESGQAFLAG
                     HAVARSVDEGFLAGDPRRGLLWLGVALVAVLSGARVVRGVFAQLAGVTEPLRDGLVRRA
                     VDRSMARAAPGGPGGTDRAAVSRLTNQVEIARDSFAGLVLSLRSFVFTAAGALLGLLSL
                     HPALLLVVLPPLAAGLALFLVTLRPMAAAQRRALAADEALGEHAASARAALRDLAACGT
                     GPGVEQRGADLVADAAAAARTLAGWAAVRTAALGVAGHLPVLALLVAVEWLRGRGVSVG
                     ALLGAFTYLVQSLLPALHTLMTALGAAGSRLLVVLDRILGPEPEPESESEPESEPESEL
                     GSGPGPELGSVPESRARLSTASAPGATAFAAHTAAPPAVELRAVTLSYGVRAEPVLDTL
                     DLRVAPGEHLAVVGPSGIGKSTLTRLVAGTLAPSRGEVRVAGRPVTGRPAVELAALRVL
                     VPQDAYVFSGTVGDNLAYLRTDACRAELDAAVGVFGLAPLVERLGGLDGTVRPAELSPG
                     ERQLVALVRAYLSPAPLLLLDEATCHLDPASEARAEEALAGRPGTLVVVAHRLSSAVRA
                     HRTLVLDGVRAQCGTHAELLGRSPLYRDLTGHWNS"
     gene            complement(7913..9718)
                     /locus_tag="B9W62_RS05690"
                     /old_locus_tag="B9W62_05705"
     CDS             complement(7913..9718)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327827.1"
                     /locus_tag="B9W62_RS05690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05705"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_256976195.1"
                     /transl_table=11
                     /translation="MRKSRPVPPRAPGRALETLVLLCSAAAALAAVAQPLALGRTLDLL
                     LRDGDAGWWLPLSAGLLLGELLLDSATSLFTGRCNATWAASVRTRALRGLLRTAPDHAR
                     PYPPGDIGTRLTLNAADAGGAPAARAALAASLITPLGALVALALVDVWVALCVLTGLPA
                     LALLLRSFARDTGATVAAYQRTQSLIASRLLEALEGADTIGAAGTGERERARVLAPLAE
                     LAAQGRHMWALHGRALGRSGVLVPLLTLAATAVGGLRLAAGELSVGDLLAVGRYAQLTA
                     GVGAAASLLGAIVRAREARRRTRELERMPATAYGTRRLPANGPGELRLCGVRVLRGGRE
                     VLRADGVRVPGGSTVAVVGRSGAGKSVLAAVAGRLIDPDEGHVLLDGVRLDRLTHEALR
                     TEVAYAFERPVLGEGTVAEAIATGARRPSRERVRQAARAAGADGFVRRLPHGYDTPLPR
                     APLSGGEHQRLGLARAFAHAGRLLVLDDATSSLDTATEHEVDLALRRSVRPGTRLVVAH
                     RPSVADRADLVLWLEDGRVRAVGTHRELWHTAGYREVFGAGAAADTDAGPGPGPGPGPG
                     PGGGGGVGGSGPGTVRRPEPEEARP"
     gene            complement(9835..9963)
                     /locus_tag="B9W62_RS05695"
                     /old_locus_tag="B9W62_05710"
     CDS             complement(9835..9963)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849360.1"
                     /locus_tag="B9W62_RS05695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05710"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_003972313.1"
                     /transl_table=11
                     /translation="MNLFDLQSMETPKEEAMGDVETGSRASLLLCGDSSLSITTCN"
     CDS_motif       complement(9901..9963)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNLFDLQSMETPKEEAMGDVE"
                     /locus_tag="B9W62_RS05695_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9835..9900)
                     /prepeptide="core"
                     /locus_tag="B9W62_RS05695_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="32.20"
                     /molecular_weight="1955.2"
                     /monoisotopic_mass="1954.0"
                     /core_sequence="TGSRASLLLCGDSSLSITTCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNLFDLQSMETPKEEAMGDVE"
                     /leader_location="[9900:9963](-)"
                     /alternative_weights="1973.2"
                     /alternative_weights="1991.2"
                     /alternative_weights="2009.2"
                     /alternative_weights="2027.3"
                     /alternative_weights="2045.3"
                     /alternative_weights="2063.3"
     gene            complement(10001..12730)
                     /gene="lanKC"
                     /locus_tag="B9W62_RS05700"
                     /old_locus_tag="B9W62_05715"
     CDS             complement(10001..12730)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972314.1"
                     /locus_tag="B9W62_RS05700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05715"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_179235367.1"
                     /sec_met_domain="micKC (E-value: 2.5e-232, bitscore: 772.2,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 6.7e-10, bitscore: 37.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 8.7e-05, bitscore:
                     20.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKGYAVYCDADPYFYDAPHRTADRTGAARSRYAAASSPVPQGWQ
                     RHESGDWLALRPAEADLPAQGWKIHVSACLDNAEGVLDRVWRHCVGGGTAFKFVPSRYL
                     LHQRNAKYADRAGSGKFVTVYPANEAEFERLVGELSELLAGEPGPHILSDLRIGDGPVH
                     VRYGGFTRRDCYDADGELRPAVSGPDGVLVPDLRGPVFRVPEWVDPPAFLRPHLDARSA
                     VTVTGMPYAVESALHFSNGGGVYLARDTRTGARVVLKEARPHAGLAADGADAVTRLHRE
                     RRALERLSGLDCTPEVLDHLTVGEHHFLVLEHIDGKPLNTFFARRHPLIEADPGERRLA
                     EYTDWALDVHARVERAVAEVHARGVVFNDLHLFNIMVRDDDSVALLDFEAAHHVDEAGR
                     QIVANPGFVAPADRRGVAVDRYALACLRLALFLPLTSLLAVDRHKAAHLAEVVAEQFPV
                     DRAFLDAAVDEITRVDGGTRVDGSTRVDGSTRSDEVAHLDVTVPLDGAARVHRAPAAGR
                     PGAPVAPVRPDDWPRSRDSMAAAIRASATPSRTDRLFPGDIAQFATAGGGLAFAHGAAG
                     VLYALAESGAGQDEDGEQWLLERTKRPPSGMPLGFHDGLAGLAWTLERLGHRDRALDLA
                     ELLLDQPLDHLGPDLHGGTAGLGLALESLAATTGQAALHSAALHCAELAADGLRGEGGP
                     AGRAGRGRARAGLLYGGAGRALLFLRLFERTRDSALLDLARDALRQDLARCVRGAGGAL
                     QVDEGWRTMPYLGAGSVGIGMVLDDYLAHRADEEFARAADEIVAAAQAMFYAQPGLYRG
                     VAGMVLHLGRTTATAPGTGPRAVRRQLHALSWHAMSYRDRLAFPGEQMMRLSMDLSTGT
                     AGCLLAVASVLGDAPAGLPFLPPPRRSGGPPTRPHQEP"
     misc_feature    12762..12774
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    complement(12822..12839)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.66"
                     /tool="antismash"
     gene            12956..14029
                     /locus_tag="B9W62_RS05705"
                     /old_locus_tag="B9W62_05720"
     CDS             12956..14029
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031099.1"
                     /locus_tag="B9W62_RS05705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05720"
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="WP_087805793.1"
                     /transl_table=11
                     /translation="MPHMTAFARNQWYVAAYSHEVGRELLGRTVLGEPLVLYRAEGDGS
                     PVVLHDRCVHRRYPLSEAPTRLDGDRIVCGYHGFTYDTTGTCVYVPGQKRIPRTARVAS
                     YPVAERDSLVWVWIGDPALADPEAVPRARHLDAPGWVTVRGMEPIDADYGLLVDNLLDL
                     SHETYLHGGYIGTPEVAETPITTEVDEGAGIVRVSRHMDDAECPPFYARSTGIGGRIDR
                     WQDIEYHAPCLYLLHSRVAPTGVVPAPDGSDPDGFHTEITYAITPSGDGKVYDFWAVSR
                     DWATDDAEVTEFLYKNNRTVVMQDVDALTLLQRTLGGERTGYQELSINIDTGGLAARRI
                     LARLVEEGAGAGPRAAR"
     gene            14026..14196
                     /locus_tag="B9W62_RS05710"
                     /old_locus_tag="B9W62_05725"
     CDS             14026..14196
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972316.1"
                     /locus_tag="B9W62_RS05710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05725"
                     /product="hypothetical protein"
                     /protein_id="WP_087805795.1"
                     /transl_table=11
                     /translation="MSGRTGEVYRVDWLPGTDVLRGTCHCGAEHTAEDPVAMWDWMLAH
                     PRGHHLPGDGS"
     gene            14193..15134
                     /locus_tag="B9W62_RS05715"
                     /old_locus_tag="B9W62_05730"
     CDS             14193..15134
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972317.1"
                     /locus_tag="B9W62_RS05715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05730"
                     /product="PDR/VanB family oxidoreductase"
                     /protein_id="WP_087805796.1"
                     /transl_table=11
                     /translation="MTRYEAELVVARRETAADGVLVLTLRHPMGEPLPAWEPGAHVDVV
                     LGPGLERQYSLCGDPADRAQWRIAVLREREGRGGSAYVHGELRAGDEVRVRGPRNNFRL
                     ESAPRYRFVAGGIGITPVLPMLAAAEEAGAEWTLLYGGRTRAAMAFTQEVARFGDRVTI
                     VPEDESGLLDLGPVLDGLAPDTLVYCCGPGPLLDAVEARCPAGSLRVERFRPKEADGDA
                     PAEAEFDVVLARSGRTVVVPPGVSVLDAVRGAGVEVLYSCTEGTCGTCETEVVEGDPEH
                     RDSVLTEEERAAGETMLICVSRCRGRRLVLDL"
     gene            15278..16249
                     /locus_tag="B9W62_RS05720"
                     /old_locus_tag="B9W62_05735"
     CDS             15278..16249
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069827.1"
                     /locus_tag="B9W62_RS05720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05735"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_087805798.1"
                     /transl_table=11
                     /translation="MRRLFVGLTAVSVLAAATACGSSDDSGGSDGSGSSGSTTEVEVGL
                     IPIVDVAPLYLGQKKGFFEKQGLKLSFSSAQGGAAIVPGVVSGQFEFGFSNMTSLLIAQ
                     SNGVPVKAVANGIASTGEVGKDFEALTVKGDSPIRSPKELAGKKVAINTLKNINETAVR
                     ASVRKAGGDPDEVELVELAFDQMPAALDAGRIDAAMVVEPALATIKSRGGREIASPMID
                     VAPDLTVAMYFTSATYAREQPEVVKKFQAATAESLAYADAHPDEVREIVTTYTKIPADV
                     LAKVTLPKWPAEPNRAGVEELARLGEADGLFKRAPDLDELLP"
     gene            16246..17019
                     /locus_tag="B9W62_RS05725"
                     /old_locus_tag="B9W62_05740"
     CDS             16246..17019
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386048.1"
                     /locus_tag="B9W62_RS05725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05740"
                     /product="ABC transporter permease"
                     /protein_id="WP_087805800.1"
                     /transl_table=11
                     /translation="MRGADAALGAAGLAGFLALGEAVPRLGLVEEEYFPPTSRIADALG
                     TEVADGAFWTALGDTLTGWALGLAVAVGAGIVVGVLLSVVPYLREATASTIEFLRPIPS
                     VALIPLAVLLFGTELRSVLLLVVYASFWQVLIQVLYGVRDVDPVAEETARSYGLGAWAR
                     IRYVLWPTALPYVMTGVRLAAAVALILAVTAELVVGAPGLGARIAVAQTSQAVPEMYAL
                     IVVTGLLGLLINVGARSVERRALAWHQSVRGEVAV"
     gene            17016..17795
                     /locus_tag="B9W62_RS05730"
                     /old_locus_tag="B9W62_05745"
     CDS             17016..17795
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020122243.1"
                     /locus_tag="B9W62_RS05730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05745"
                     /product="ABC transporter permease"
                     /protein_id="WP_087805802.1"
                     /transl_table=11
                     /translation="MRRLLLRLVFVLALPVVLVAVWWVASSGSEDVYWPPLGTIVSAFP
                     DVWTGERWRGDVLPSVLRLAAGYALAGAVGVALGTLIGSYRRVRAVCEPVLEFLRAVPP
                     PVLVPVIMLFAGIGDTMKVVVIASGCVWPVLLNTVEGVRAVDAVTAETARSYGITGAAR
                     LRHVVLPSASPQIFAGLRQALSVGIILMVISEMFAASNGLGFTVVQFQRSFAIPDMWTG
                     ILLLGLLGFVLSVLFQLVERRALGWYHGLRAASRRSR"
     gene            17857..18678
                     /locus_tag="B9W62_RS05735"
                     /old_locus_tag="B9W62_05750"
     CDS             17857..18678
                     /EC_number="7.6.2.14"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386046.1"
                     /locus_tag="B9W62_RS05735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05750"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_087805804.1"
                     /transl_table=11
                     /translation="MLDVRGLRKVYEGSGRRVEAVRDLTFSVAAGELVCLVGPSGCGKT
                     TLLKCVGGLLEPTAGEVFLAGRRVTGPPPGMAFVFQEYGRSLFPWMRVGENVELPLKRK
                     DLAKGRRRELVADALASVGLADAAGAYPWQLSGGMQQRVAIARALAYEPEVLLMDEPFA
                     AVDAQTRADLEDLVRALWRERGITVLFVTHDIDEAVYLGQRVIVLSASPTVVREQLRVD
                     LPDGRDQVHTRVAPRFAELRTRVYEQIQAAKRGAARSPFKEPQGADTPPPH"
     gene            complement(18686..19345)
                     /locus_tag="B9W62_RS05740"
                     /old_locus_tag="B9W62_05755"
     CDS             complement(18686..19345)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069850.1"
                     /locus_tag="B9W62_RS05740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05755"
                     /product="hypothetical protein"
                     /protein_id="WP_087805806.1"
                     /transl_table=11
                     /translation="MAFQAGGQRSAPRPTPATPEAQAYLQDYTALLEAVPFPSLVVDHR
                     WDVVLANGAFRTLFQGAGPHPTAMPDDNFLRFVLFHPDAATVLGEHESSWCLPMLAHFA
                     ATLERYGHDPGLQAVRRDIAQDPIMEAAYRQGLPHWVRAVGARAVEHDGAVRPLHHPDP
                     RRGTTECRVVVETPGALQELGYTRLTLVLREPRRTGQRPPRARRAAAHLRVVPVAE"
     gene            19577..20245
                     /locus_tag="B9W62_RS05745"
                     /old_locus_tag="B9W62_05760"
     CDS             19577..20245
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004980713.1"
                     /locus_tag="B9W62_RS05745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05760"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_087805808.1"
                     /transl_table=11
                     /translation="MTGGFEGQGVMPTPTPTTTPTAVVARVGALADRLGVPHTEVFDVG
                     RLSAASGVPESVVGALLGGRPAGEPDVQTRFVQRLDLLRRTRLKPNGRKYTQQEIADGA
                     GMSRQQAGALINGDRRPTMEHCDAIQRFFGVHAGFLTAEDPEALAGALQRTEQELLQQL
                     ADREREAAAAADDPLERLLQDHGVRGIAWRAAQLPTDQHRDKVAEWLDMLLESVKRPES
                     "
     gene            20371..20607
                     /locus_tag="B9W62_RS05750"
                     /old_locus_tag="B9W62_05765"
     CDS             20371..20607
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431523.1"
                     /locus_tag="B9W62_RS05750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05765"
                     /product="hypothetical protein"
                     /protein_id="WP_087805810.1"
                     /transl_table=11
                     /translation="MTTAVLTDHERTAVQAYLRLLHTVRAGFDAGAGPDGPPRPPVVPP
                     SVLAEAEEALRAAGLTGNEEAFFRLLRDWCPRP"
     gene            complement(20636..21316)
                     /locus_tag="B9W62_RS05755"
                     /old_locus_tag="B9W62_05770"
     CDS             complement(20636..21316)
                     /NRPS_PKS="Domain: ACPS (103-167). E-value: 9.7e-21. Score:
                     66.0. Matches aSDomain:
                     nrpspksdomains_B9W62_RS05755_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031096.1"
                     /locus_tag="B9W62_RS05755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05770"
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="WP_087805812.1"
                     /transl_table=11
                     /translation="MIEDLLPDTVVTVEAFGHDDAGHLPLYPEEEELVARAVAKRRREF
                     TVVRSCARRAMEKLGVPAQPVLTGERGAPRWPDGLTGSMTHCDGYCAAALVRVTDLASL
                     GIDAEPDGPLPDGVLKTIALSSETARLRRLDEARPDVHWDRLLFSAKESVYKAWFPLTG
                     KWLDFAEADIEISVDPADPRRGTLHAALLVPGPTVGGRRLSHFDGRWTAREGLVTTAVA
                     VPRT"
     aSDomain        complement(20816..21007)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9W62_RS05755_ACPS.1"
                     /evalue="9.70E-21"
                     /label="B9W62_RS05755_ACPS.1"
                     /locus_tag="B9W62_RS05755"
                     /protein_end="167"
                     /protein_start="103"
                     /score="66.0"
                     /tool="antismash"
                     /translation="LGIDAEPDGPLPDGVLKTIALSSETARLRRLDEARPDVHWDRLLF
                     SAKESVYKAWFPLTGKWLD"
     gene            complement(21313..22200)
                     /locus_tag="B9W62_RS05760"
                     /old_locus_tag="B9W62_05775"
     CDS             complement(21313..22200)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031095.1"
                     /locus_tag="B9W62_RS05760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W62_05775"
                     /product="metallophosphoesterase"
                     /protein_id="WP_087805814.1"
                     /transl_table=11
                     /translation="MTSRAGAPGKLWAISDLHIGYKENRTLVERMRPESDDDWLLVAGD
                     VAETVADIRWALGTLADRFRRVVWVPGNHELWTHPKDAVALRGVARYRHLVEMCRELGV
                     TTPEDPYPVWEGAGGPAVVAPLFLLYDYSFLPAGCANKAEGLEYAHGTGVVCSDEYLLH
                     PDPYPSREAWCRARVEETGRRLAEIPADLPIIPVNHYPLHRHPTDVLWYPEFAMWCGTA
                     LTADWHRRFRVDTMVYGHLHIPRTTWHEGVRFEEVSVGYPREWRKRSGPPGRLRRILPS
                     EQAPAAPSRQEVSR"
     misc_feature    22228..22244
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.41"
                     /tool="antismash"
ORIGIN
        1 ccaggtccac gaacccccgc agggcgtcgg cgggtgccca gccgacgggt tcgacggtgc
       61 ggacggcgtc atgcagcacg tcttcgggca gcggggtgcg tctgcccagc cgctcgttcc
      121 agacctcggc cgcgcgggcg gtgtcggggc cgtgcgtcca gagccgggac ggttcggtgg
      181 gcagcagtgc cgccaccacg gcccgcaggg cggcgctgtc gagggacctc agctcgtcct
      241 tggccacgcg ggcgtcggcc gacttcaccc cgatggcctt cagggtcgcg gccggcaggc
      301 tcgcgcgctt gtcgtcgatc tgcggcgtcc cggcgagcac gagccgggcc gtggtcgggg
      361 tgacgccggt gcgccgggcg aactcctcgg cggcctcggg gcgccagggc gcggggccgc
      421 gctcggccag ttcggcgcgg aaggcggcga cccagccggg ggcccgggtc ggctccggca
      481 cgaacggctc ccaggacacc ggcgtgtagg gggccggtgt ctcgaagcgg ccggacgggt
      541 cgtggtggac cgcgccatag tgcttgccct tgacctcgtg gggtccgtac tcgcggacga
      601 actggtacca gtcgtcgggg aagacgagga actccccgcc ctccaggtcg agcacggtcc
      661 cccgggtgta cccgtgcgtt ccgcccggcc cgtcgaacgt ggcggggtcg aaggccaggt
      721 ggacgcggcg ccagtggccg gggtccagct ccgtcagccc gtgcgcgtcg agttcgccga
      781 ggaaggtgtc cagggcctcg cggtgctccg tcacggtggc ctgcgaggcg gccctcagcg
      841 ccagtacggc gggcagctcg ggcagggcca ccgcgttcag gtgctccaac ggcgcccgtt
      901 tgtcgagcga caggtgcagg atgccggcgg gggccggttc ggcctcgccc ttcatcgacc
      961 gggagaggag ccgcggcaga tcgaagaggt cgtgccggaa gtcgtagtac ccacgcgcgt
     1021 cgcgttcggt caggccggcg ccgttgagcg ccgaggcgag caggcggtcg ccgagcgcgg
     1081 gtcgcggttc ctccgggctc tcgccctgga ccgccgagtc cagccgggcg agcagcccgt
     1141 ccaggacgcg ctgctgctcg gcggcgtagc gcgccacgcc gctgatgccc cggagcagcg
     1201 cctcgtggcc gacctccggg aacagggtgc ggacgggtgc gagcaccgcc tcccggtccg
     1261 ccgcctcgtc cccggccgtc tcggccacgg ccgccgccag cagctccgtc gcgaggtcgt
     1321 cgccgacccg gcggagcgcc gcggagccct gcgggtcgcg gggcacgagc aggtgccagt
     1381 agcgcagggg cggcagcagg ggggtgcccg cggagaaggg gccggctgtc tgatcaccct
     1441 tgaagtgggc gagcaccgcc tgctcggagt cccgcagttg gagggcgctc gaccatcgca
     1501 tcacggtgac gacccggtcg gtgccgggga agaccagcgc gttctccggg ttcccgccca
     1561 cgcgccacgg tacgacgacc gtgtggccgg ccaggtcctc tccttgccgc gagccgtcgg
     1621 gccggacgat cacccgccag ccgagcagcc cgtccaccgg ggcgcacatc gggcccggct
     1681 cggcggacgg ggcgggcagc agccaggcgg cgccgagggt gctgccctcg ggcgcggcac
     1741 gcagcccttc ggtgaaccag tccggcgcgc cgcgctcccc caccgtgtcg tcggccggtt
     1801 cataggcgtg ccagccactg ttccgctcgg cggaccagtc gtcgacccag agccagtacg
     1861 acgtgccgtc gctgatcacc tgtcgccgcc acgggacgtg ggtgtccccc ggccgtagca
     1921 ctccgcggcc gctggtcctg ccgcccccgg ggagcggaag ggtgacggac ggcatgccgt
     1981 tcgtcccgcc cttcccgtcc acgtggcagg tgtaggagga gcgcacgtca ccgtcgagtt
     2041 ccgtcgtcgg cgagatgccg gtgtcggggt ggtaccagta gccgtacgag gtggacgggc
     2101 cggacgcgta ccaggagacg agcagtccgc cgtccacgta ccggacgtcg gggcggcccg
     2161 ggcccccctc gtccgggagg cgcagttcgt gacggagaac agtgccctgc gggccgagca
     2221 cccggacgtg cgtgccgtcg aggacgacga ggtgcggcca ggcctcggcc acgcgcgtct
     2281 cgcggacccg ctccggggac gcggccgagc cgatcgcctc gtcccaggcg ggccagccca
     2341 gttcgtcgac gatcccgtcg cgcagggcgc gggcgagcac gggcgccatg ccggtgccca
     2401 gcgcgtcccg cacctcctgc tcggcggtcg ccaggatctc gcccggcagc catcccagcg
     2461 tctcgaacgg accgctgttg agggcgaagt cgcccagtcc gccggtgagg tacccgcggc
     2521 tgaccccggc cacccactcg gcgagcatcg ggcggccgcc cggtgactcg gccagccggg
     2581 ccacggtgcg cttgtcgatg ccctcgcgct cgtaggtggg gcagccgctg cggaagactt
     2641 cccggaagcg ggtgtcggcc gccagggcga ggaggtcgcg ccgtccgtcg cgggccgccc
     2701 actcctggag gttgagccac gggcggtcct cgggggtccc gaccgggacg tccagggcga
     2761 ggagctggtc gaggaggttg acgtcgccga cgggcggccg caacgtaccg ttctcgtcgt
     2821 tcagttcggc gcggagggca tcggccatgc ggtcgaggag ggggtacagc tcggagggcg
     2881 cgatgtgccg ctcgtgggtg cggcacaggg cgaggaacct gcgggtccag ccggcggtgc
     2941 cgtcgggcga ccgggcctcg gcgggcagcg tggcgtcgca cagtccctcg gtggcaccgg
     3001 tcttctccag caggtcgagc cactgcccga gctcctcgtg ctcccactcg gaggggagca
     3061 gtccgagcag ggtgccgcgg gcggcgggtt cccgccgggt cagttccagc agggcggccc
     3121 ggtgggcctt ccaccagccg ggcggtgcct tgagggtgcc gggcagcggc agcacctcgc
     3181 gcaggtacgc catctcctcg gcgagggctc ccttgcccgc gacggccttc gccagctttc
     3241 gcaggtcacc cgcgccgggg ctcgacggtg ccacgccgtg cgcggcgagc cggacgaaga
     3301 ggccgcgcag gtgccggaag gcggtggcgg ccggcacccg ggacgagagt cccttggcat
     3361 aactggagag cactttggtc ggcatggcgt cggcgagcgc gaactccagg aacaccgcgt
     3421 ccatgcgggc ctcgtcgaac ggcagggcgt gggccgtctc ggccttgcgc gcgttgacga
     3481 acatctggga ggcgtacgcc ttctcgccgg cggccaggaa cacccggccg gcctcctcgt
     3541 agaaggtggg caggaagtgg ggcacggagc ccgcgaggcg ctcgccgatc gactcgtagg
     3601 cggcgcgggc ccgcttcgcc cgggtacgca ccgtccgcgc gaccttgttc atctcctcga
     3661 cgagcgacat cgcgagatgg ccgtcggagg ggtggcggac cagcacccac tcggggaagc
     3721 ccatggcccg gtgctgtccg acgccgacct cgaccggctc gcccacgggc agcagtccga
     3781 ggaatccgcc tccgcccccg tctgcggcgt ctcccgcggc gggctcggtg ccggacgggt
     3841 cggcgggcgt caggcgtacg acgatccggt cgtcgaggcc cggatgccgg taggcccggg
     3901 tgaacacggg cacggcccgg tcgcctcccc cggtggtgcc gggcggcagt acggctccgg
     3961 cgcgcagcag ctccgccacc tcttccgccg cctcgtgccg tgtcgtgccg tcgctcatga
     4021 tcgcgtgcct ttcatgggta tgcgtgtcgc tgtggcgttc actcggcgcc gtccgtgggc
     4081 acggtgcggc cggcgtgcag ggcggctgcc atccgcatgc cctcggagta ggcgacgggg
     4141 ccgacctcgt gcagcggaag actccggtac ccgtccccgt gactccagct gaggccgccg
     4201 gtccaggcct tctcctcggt ataggggtcg ctcatgccga cggaggcggt gaagacgcga
     4261 ccggcgtccc ggacgcggtc gacgatgcgg ctcccggaga tccggtagcc gagggacgtg
     4321 gcgcgggcgg acaggtggaa ccacgagcgg tactcggcgc ccgcgaactc ggtgaccacg
     4381 tcggtgccgc cgtcctcacc cgccccggga gccgtccagg tggcccggtg gatctgctcc
     4441 acgccctgca ccacgcccaa ctcggcggcg aaggtgcgca gttcctccag atcggggagg
     4501 agcaccgggt ggggcatggt gaccgtgcgg gggttcaggc ggacggtctc gccgtccagg
     4561 ttcaccaccc gcagcccgtc cgactcgtcc gcgtcgcgca ggaagccgac ctcgtcgggc
     4621 gcctcgccga ccacgacgat gtcacgcagc gccgtctgcc acgcctcgtc gggccacacc
     4681 cgggcgagca gcccggtcgg caccgggagc gaggacacca tccaggtgcc gacctgcgcc
     4741 gcgcactcgg cggcgtgccg gtccagccac tcggcgaagc gctggagttc gaccacctcg
     4801 gggcggtccc gtatctccgc gggcagcgtc cgctcccgct tcccctccga agccgtcccc
     4861 gccgccgcgg tggaccgcgc caccacccgg ccctcgacca gggcgacttc gtacgtgtcg
     4921 cccgctgcca gccaacccat cagctcttcg cctctcccag tactaggtac acggcacagc
     4981 accccgggcc cttgaatcgg cacactccgc tgtggcgttg gccaaagact aggggcaccc
     5041 accgacagcc tcgggagccg tccgcgcggt gcctttcgcg ccagattgga cagcggcggc
     5101 tttcggccgg gcccggtatc gccaggacct cgggccgatc gggcccgggc ggcgcgcgcg
     5161 gccggccacg ggcggcggaa accgccctgg ccaggacgcc aggggccgcg acgcgaggac
     5221 ggcggactct cgtcggttca cacacgggcc gaagtcgtcc ggcggattgg tgtgttatcc
     5281 gcccttcttc gctgccgcac ccgtctcgat cgtcccccga caagcctctg acgacggcga
     5341 attgcctccg atgcggttcg cacgtgcgta cgcgtcgtgt tccgccgtcc cggatggggg
     5401 cacatggccc gatggcgcgg gggcgcgcgg agcccggcgg cccgaacggg gccgccgctg
     5461 acaaggggtg ggggagatgg ttcgtattgc cgtggtgcac gacgagaaac tgctgcggtc
     5521 ggcactggtg caactgctca gatccgacga cacgctggac gtgacctcgc actgcctcga
     5581 cgccgacggt ccggagccgg gtgcggcatt gcccgccgac gtctgtgtcg tggacggaga
     5641 gtgcctgacg gggccggaag tcgcaggcgc cggacgtcta cgggcccggt acggggaccg
     5701 gctcgtggtc ctggcgacag ccaagcggcc gggagtgctg cgccgggcct tcgacggggg
     5761 cgccctcggg ctggtcgaca agaacgcccc ggcccatcgg ctgatcaccg ccgtgcacac
     5821 ggtcgcccag ggcgaacgct tcctggacga gacgctcacc gtggccctgc tgaagggcgc
     5881 ggagatgccg ctgaccacga gggaactggg cgtgctggcc ctggcttcgc agggggcgcc
     5941 gatcgccgag atcgcggcgc gtctgcacct gtcccggggg acggtccgca actacttggc
     6001 cacggcggtc cggaaggtgg gtgcccgcaa ccgcgtcgac gcgatccgca tcgtccagag
     6061 cgccggctgg acctgacgcg tcacgagttc cagtgtcccg tcaggtctcg gtagaggggc
     6121 gaacggccca gcagttcggc gtgcgttccg cactgcgccc gtacgccgtc cagcaccagt
     6181 gtccggtggg cacggaccgc cgaggacagc cggtgcgcca ctacgaccag ggttccgggc
     6241 cgcccggcga gggcctcctc cgcgcgggcc tcggaggccg ggtcgagatg gcaggtggcc
     6301 tcgtcgagca gcagcagcgg ggcgggcgac aggtacgcgc ggaccagcgc gaccagttgc
     6361 cgctcccccg gcgagagctc ggcggggcgc accgtgccgt ccagcccgcc cagccgctcg
     6421 accaggggag cgagaccgaa caccccgacg gccgcgtcga gttcggcccg gcacgcgtcc
     6481 gtcctcaggt acgcgaggtt gtcgccgacg gtgccggaga acacgtaggc gtcctgcggg
     6541 accagcaccc ggagcgcggc gagctcgacg gcggggcgcc ccgtcaccgg gcggccggcc
     6601 acgcgtacct cgccgcggct cggcgcgagc gttcccgcga cgaggcgggt gagggtcgac
     6661 ttcccgatgc cgctcggtcc cacgacggcc aggtgttcac ccggcgcgac gcgcaggtcg
     6721 agcgtgtcga gcacgggctc ggcgcggacg ccgtaggaca gggtgacggc ccgcagctcg
     6781 accgccgggg gcgcggcggt gtgcgcggcg aaagccgtcg cccccggtgc gctcgcggtg
     6841 ctcagccgcg cccgcgactc cggcaccgac cccaactccg gccccggccc cgaccccaac
     6901 tccgactccg gctccgactc cggctccgac tccgactccg gctccggctc cgggccgagg
     6961 atccggtcga ggacgaccag cagccgggac cccgccgcgc ccagcgcggt catcagggtg
     7021 tgcagggcgg gcagcaggga ctggacgagg taggtgaacg cgcccagcag cgcccccacg
     7081 ctcacccctc gcccgcgcag ccactccacc gccaccagca gcgccagcac gggcaggtgg
     7141 cccgcgacgc cgagcgccgc cgtgcgcacc gccgcccatc cggccagcgt ccgggccgcc
     7201 gcggcggcgt cggcgaccag gtccgcgccg cgctgctcca ccccgggccc ggtcccgcag
     7261 gcggcgagat cccgcaacgc cgcacgcgcg ctcgccgcgt gctcgcccaa cgcctcgtcg
     7321 gccgccaggg cccggcgctg ggcggccgcc atgggccgca gcgtgaccag gaacagcgcg
     7381 agcccggccg ccagcggggg cagcaccacc aggagcaggg ccgggtgcag ggacagcagg
     7441 ccgagcagtg cgccggcggc ggtgaagacg aaggaccgca gggagaggac gaggccggcg
     7501 aagctgtccc gggcgatctc gacctggttc gtcagccgtg agacggccgc gcggtccgtc
     7561 ccaccggggc cgcccggcgc cgccctggcc atggaccggt cgaccgcacg ccgcaccagg
     7621 ccgtcgcgca gcggctccgt caccccggcg agctgcgcga acacaccccg gacgacccgg
     7681 gcgccggaca gtacggcgac cagcgcgacc ccgagccaca gcagtccccg gcgcggatca
     7741 ccggcgagga acccctcgtc gacggagcgc gcgaccgcgt ggccggccag gaaggcctgc
     7801 cccgactcgg ccagcgacca gagcgcgagc cgtaccagca ctcccttgcg gtgggcgagg
     7861 aagcggcggg ccggcggtgc gaggcggcgc agcgccccgg cctcggcgga cgtcacgggc
     7921 gcgcctcttc gggctcggga cgccgtacgg tccccgggcc actgccgccg acaccgccac
     7981 cgccaccggg accgggaccc ggacccggac ccggacccgg accggcatca gtatcggctg
     8041 ccgcgccggc gccgaagacc tcccggtacc cggccgtgtg ccacagctcg cgatgggttc
     8101 cgacggcgcg cacccgtccg tcctccagcc agagcaccag gtcggcccgg tccgcgaccg
     8161 acgggcggtg cgccaccacg agcctggtcc ccggccgcac cgagcgacgc agcgccaggt
     8221 ccacctcgtg ctccgtggcg gtgtccagac tggacgtggc gtcgtccagc accagcagcc
     8281 gcccggcgtg cgcgaaggcc cgcgccagtc cgagccgctg gtgttcccca cccgagaggg
     8341 gtgccctcgg cagcggggtg tcgtagccgt gcggcaaccg gcgtacgaag ccgtcggcgc
     8401 ccgccgcccg ggcggcttgg cgtacccgct cacgcgacgg ccgccgcgcc ccggtggcga
     8461 tcgcctccgc gaccgtgccc tcccccagta cggggcgttc gaaggcgtac gccacctcgg
     8521 tgcgcagcgc ctcgtgcgtc aagcggtcga gccggacgcc gtccagcagg acatgtccct
     8581 cgtcggggtc gatcagccgt cccgcgacgg ccgccaggac ggacttgccc gccccgctgc
     8641 ggccgaccac cgcgaccgtg ctgccgcccg gcacccgcac gccgtcggcg cgcagcacct
     8701 ccctgccgcc gcgcagcacg cgcaccccgc acagtcgcag ctctcccgga ccgttcgcag
     8761 gcagccgcct cgtgccgtac gccgtcgcgg gcatccgttc cagctcccgg gtccggcgcc
     8821 gtgcctcacg ggcccggacg atcgccccga gcagggacgc cgccgcgccg acgccggccg
     8881 tgagctgcgc gtaccggccg acggcgagca ggtcccccac gctcagttcg ccggccgcca
     8941 gccgcagccc gccgacggcg gtggcggcca gcgtcagcag cgggaccagg acaccgctcc
     9001 ggccgagcgc ccgtccgtgc agcgcccaca tgtggcggcc ctgggcggcc agttccgcca
     9061 gcggtgccag gacccgggcc cgctcccgtt cgccggttcc cgcggcgccg atcgtgtccg
     9121 cgccctccag ggcttccagc agccgggagg cgatcaggga ctgggtgcgc tggtaggcgg
     9181 cgacggtggc gccggtgtcg cgggcgaagg aacgcagcag cagcgccagg gcgggcagac
     9241 cggtcagcac gcagagcgcc acccacacgt cgacgagcgc cagcgccacc agggcgccca
     9301 gcggggtgat cagtgaggcg gccagcgccg cgcgggccgc cggagcgccg cccgcgtcgg
     9361 cggcgttgag ggtcagacgg gtcccgatgt cgcccggcgg gtacggccgc gcgtggtcgg
     9421 gggcggtgcg cagcagaccg cgcagggcgc gggtgcggac cgacgccgcc caggtggcgt
     9481 tgcagcggcc ggtgaacagc gaggtcgcgc tgtccagcag cagttcaccc aggagcagtc
     9541 cggcgctcag cgggagccac catccggcgt cgccgtcgcg caggagcaga tccagggtgc
     9601 ggccgagggc caggggctgg gccaccgccg ccaaggccgc cgcggccgag cacagcagga
     9661 ccagggtttc cagggcgcgc cccggcgccc gcggcggcac gggcctgctc tttcgcaccg
     9721 gtgagaacct ccgtacgtcg tgcgcgggca ggcgtcggcg ccccgggccg gaacccgggg
     9781 cgcccgcgcc cggcgacgtg actcaccacg tcgccgtggc cgtcaacccc tgtgtcagtt
     9841 acaggtggtg atgctcaggc tgctgtcgcc gcagagcagg aggctcgcgc ggctgccggt
     9901 ctcgacgtcc cccatcgcct cttccttggg ggtctccatc gactgcaggt cgaacaggtt
     9961 catgacgcat tcctttcgtt cggcaagggg tgtgcttttc tcacggctcc tggtggggcc
    10021 gagtcggggg gccgccgctc cggcgcggcg gcggcaggaa cggcagtccg gcgggcgcgt
    10081 cgccgaggac ggaggcgacg gcgagcaggc atccggccgt tccggtggag aggtccatgg
    10141 acaggcgcat catctgctcg ccggggaagg cgagccggtc gcggtaggac atggcgtgcc
    10201 aggacagggc gtgaagttgg cgccgtacgg cccgcggccc ggtaccgggc gccgtggccg
    10261 tggtgcggcc gaggtgcagg accattccgg ccacgccccg gtagagcccg ggctgggcgt
    10321 agaacatcgc ctgggccgcg gccacgatct cgtcggcggc ccgtgcgaac tcctcgtccg
    10381 cccggtgggc caggtagtcg tcgagcacca tgccgatgcc cacgctgccg gcgcccaggt
    10441 agggcatggt gcgccagccc tcgtcgacct gaagcgcgcc gcccgcgccg cggacgcagc
    10501 gggccaggtc ctggcgcagc gcgtcgcggg cgaggtcgag aagggcggag tcccgggtgc
    10561 gttcgaagag ccggaggaag agcagggccc gccccgcgcc gccgtacagc agcccggcac
    10621 gggcgcggcc gcggccggcg cggccggccg gcccgccctc gccccgcagg ccgtcggcgg
    10681 ccagttcggc gcagtgcagc gccgccgagt ggagcgcggc ctgaccggtg gtggcggcca
    10741 gcgactccag ggccaggccg agaccggcgg tgccgccgtg caggtccggg cccaggtggt
    10801 cgagcggctg gtcgaggagg agttcggcga ggtcgagggc gcggtcgcgg tgaccgaggc
    10861 gctccagggt ccaggcgagt ccggcgagcc cgtcgtggaa accgagcggc atgcccgacg
    10921 gcggtcgctt ggtccgctcc agcagccact gctcgccgtc ctcgtcctgc ccggccccgc
    10981 tctcggccag ggcgtacagc acccccgccg caccgtgggc gaaggccagc ccgccgcccg
    11041 ccgtggcgaa ctgcgcgatg tcaccgggga agaggcggtc cgtgcgggag ggcgtcgcgg
    11101 aggcgcggat cgccgccgcc atggagtccc ggctgcgcgg ccagtcgtcg ggccggacgg
    11161 gcgccaccgg cgcgccgggc cgccccgccg ccggagcgcg gtggacgcgc gcggccccgt
    11221 cgaggggcac ggtcacgtcg aggtgcgcga cctcgtcgct gcgcgtgctc ccgtcgaccc
    11281 gcgtactccc gtcgacccgc gtgcccccgt cgacccgcgt gatctcgtcg accgccgcgt
    11341 ccaggaaggc ccggtccacc gggaactgct ccgccaccac ctccgcgagg tgcgccgcct
    11401 tgtgccggtc gacggccagc agactggtga gcgggaggaa cagcgcgagc cgcagacacg
    11461 ccagcgcgta ccggtccacc gccaccccac gccggtcggc gggcgccacg aaccccgggt
    11521 tcgccacgat ctgccgtccc gcctcgtcga cgtggtgggc ggcctcgaag tccagcaggg
    11581 cgacgctgtc gtcgtcccgg accatgatgt tgaacaggtg caggtcgttg aagaccacac
    11641 cccgggcgtg gacctcggcg acggcgcgtt ccacccgcgc gtggacgtcg agggcccagt
    11701 ccgtgtactc ggccagtctc cgctcgcccg ggtcggcctc gatgagcggg tgccggcggg
    11761 cgaagaacgt gttgagcggc ttgccgtcga tgtgctccag gacgaggaag tggtgctccc
    11821 cgacggtgag gtggtcgagc acctccggcg tgcagtcgag tcccgacagc cgctccagcg
    11881 cccggcgttc acggtgcagc cgggtcacgg cgtcggcgcc gtcggccgcc agcccggcgt
    11941 gcggacgggc ctccttgagg acgacccgcg caccggtgcg ggtgtcgcgg gcgaggtaga
    12001 cgccgcctcc gttggagaag tgcagcgccg actcgacggc gtacggcatg ccggtcacgg
    12061 tcaccgcgga gcgggcgtcg aggtgcgggc gcaggaaggc gggcgggtcg acccactccg
    12121 ggacgcggaa gaccggaccg cgcaggtcgg gcaccagcac accgtcgggt cctgacacgg
    12181 ccggccgcag ttccccgtcc gcgtcgtagc agtcgcgccg ggtgaagccg ccgtagcgga
    12241 cgtgcacggg cccgtcgccg atccgcaggt cgctcaggat gtgcgggccg ggctcgccgg
    12301 ccagcagctc ggacagctct cccacgagcc gttcgaactc cgcctcgttg gccgggtaca
    12361 cggtgacgaa cttgccgctg ccggcccggt ccgcgtactt ggcgttgcgc tggtgcagca
    12421 ggtagcggct gggcacgaac ttgaaggccg taccgccgcc gacgcagtgc cgccacaccc
    12481 ggtcgagcac gccctccgcg ttgtcgaggc aggcggagac atggatcttc cacccctggg
    12541 cgggcaggtc ggcctcggcc ggacgcagcg cgagccagtc cccgctctcg tggcgctgcc
    12601 acccctgcgg tacgggcgag gaggcggcgg cataccggga gcgcgcggct ccggtccggt
    12661 cggccgtgcg gtgcggggcg tcgtagaagt acgggtccgc gtcgcagtac acggcgtagc
    12721 ccttgttcac gcctgctccc tcccaccggt ggctgacgga gacgacgctg tcacgcggcg
    12781 taccgcctcg gacagttgcg gctgtcacca ctccgaggtg cggaacgcac aggtaacttc
    12841 gcggcggcgg gactcccgga gcgggagaat tccgcctggc ggaagtgctg ttgccggggc
    12901 gggacggcat ggcgaaggtg tgaccacacg acgtcgagga cgacgggagc cgcgcatgcc
    12961 gcacatgacc gccttcgcca ggaaccagtg gtacgtcgcc gcctacagtc acgaggtggg
    13021 gcgcgagttg ctgggccgca cggtgctcgg tgaaccgctc gtgctctacc gcgccgaggg
    13081 ggacggaagc ccggtcgtcc tgcacgaccg ctgtgtgcac cgccgctacc cgctgtccga
    13141 ggcgccgacg cggctggacg gggaccggat cgtgtgcgga taccacgggt tcacctacga
    13201 cacgaccggc acctgtgtgt acgtgccggg tcagaagcgg atcccgcgca ccgcccgggt
    13261 cgcctcctac ccggtggccg aacgggactc cctggtgtgg gtgtggatcg gcgacccggc
    13321 gctggccgac ccggaggcgg tgccgcgggc ccggcacctg gacgcgccgg gctgggtcac
    13381 ggtccggggc atggagccga tcgacgcgga ctacgggctg ctggtcgaca acctcctcga
    13441 cctgtcccac gagacgtatc tgcacggcgg ttacatcggc acgcccgagg tcgccgagac
    13501 gccgatcacc accgaggtcg acgagggcgc cgggatcgtc cgggtgagcc ggcacatgga
    13561 cgacgccgag tgcccgccgt tctacgccag gtcgacgggg atcggcgggc gcatcgaccg
    13621 gtggcaggac atcgagtacc acgcgccctg cctgtacctg ctgcacagca gggtcgcgcc
    13681 gaccggtgtg gtgcccgcgc ccgacggcag cgatccggac ggcttccaca ccgagatcac
    13741 ctacgccatc acgccgtcgg gcgacggcaa ggtgtacgac ttctgggcgg tctcccggga
    13801 ctgggcgacg gacgacgccg aggtcaccga gttcctgtac aagaacaacc gcacggtcgt
    13861 catgcaggac gtcgacgcgc tcaccctgct ccagcgcacg ctcggcggtg agcgcaccgg
    13921 ttaccaggag ctgagcatca acatcgacac cggcggcctg gccgcgcgcc gcatcctggc
    13981 ccggctggtc gaggagggcg ccggcgccgg accgcgggcg gcccggtgag cgggcgcacc
    14041 ggcgaggtct accgcgtcga ctggctgccc ggcaccgacg tcctgcgcgg cacctgccac
    14101 tgcggcgccg agcacaccgc cgaggacccc gtcgcgatgt gggactggat gctcgcccac
    14161 ccgcggggac accacctgcc cggggacggt tcatgacccg gtacgaagcc gaactcgtcg
    14221 tcgcccgccg ggagaccgcg gccgacggcg tgctcgtcct caccctgcgc cacccgatgg
    14281 gcgaaccgct cccggcctgg gagcccggcg cccacgtcga cgtggtcctc ggtccgggcc
    14341 tggagcggca gtactcgctg tgcggcgacc cggccgaccg ggcgcagtgg cggatcgcgg
    14401 tgctgcgcga gcgggagggg cggggcggct cggcctacgt ccacggggag ttgcgggccg
    14461 gggacgaggt ccgggtgcgc ggcccgcgca acaacttccg gctggagtcc gcgccccgct
    14521 accgattcgt cgccggcggc atcggcatca cccccgtcct gccgatgctg gccgccgccg
    14581 aggaggcggg cgccgagtgg accctgctgt acggcgggcg gacccgggcc gcgatggcgt
    14641 tcacgcagga ggtggcgcgg ttcggggacc gggtcacgat cgtcccggag gacgagtcgg
    14701 ggctgctcga cctcgggccc gtgctcgacg gcttggcccc ggacaccctc gtctactgct
    14761 gcgggcccgg cccgctgctg gacgccgtcg aggcgcggtg cccggccggg agcctgcggg
    14821 tggagcggtt ccgtccgaag gaggccgacg gggacgcccc ggcggaggcg gagttcgacg
    14881 tcgtcctcgc gcgcagcggc cgtacggtcg tcgtgccccc cggcgtctcg gtcctggacg
    14941 cggtccgcgg agcaggcgtc gaggtgctct actcctgcac ggagggcacc tgcgggacct
    15001 gcgagaccga ggtcgtcgag ggcgatcccg agcaccggga ctcggtgctc accgaggagg
    15061 agcgggccgc cggggagacg atgctcatct gtgtgtcgcg gtgccgcggc cgccggctgg
    15121 tgctggacct gtgacagagc ggcgccacac cctcggttga atcctcaacg gcccatctcg
    15181 gcaagagcat tgaccacgac tccgcgccgg ccctacgttc ccgctgagca cgttcccact
    15241 gagcacgtcc actgagcacg ttcctccagg gggagtcatg cgtcgtctgt tcgtcggcct
    15301 cacggccgtg tccgtcctgg ccgccgcgac ggcgtgcggc tcgtccgacg actccggggg
    15361 gtcggacggg tccggctcct ccgggagcac caccgaggtc gaggtgggcc tcatccccat
    15421 cgtcgacgtc gcgcccctgt acctgggtca gaagaagggg ttcttcgaga agcagggcct
    15481 gaagttgtcc ttctccagtg cgcagggcgg cgcggcgatc gtgccgggcg tggtcagcgg
    15541 ccagttcgag ttcggcttca gcaacatgac gtccctgctg atcgcccagt cgaacggcgt
    15601 gccggtgaag gcggtggcca acggcatcgc ctcgaccggc gaggtgggca aggacttcga
    15661 ggcgctcacc gtgaaggggg acagcccgat ccggtcgccg aaggagctgg cgggcaagaa
    15721 ggtcgccatc aacacgctga agaacatcaa cgagaccgcg gtacgggcct cggtgcgcaa
    15781 ggcgggcggc gaccccgacg aggtcgagct ggtggagctg gccttcgacc agatgccggc
    15841 cgcgctcgac gccgggcgga tcgacgcggc gatggtggtg gagccggcgc tggccacgat
    15901 caagagccgg ggcggccggg agatcgcctc ccccatgatc gacgtggcgc ccgacctcac
    15961 cgtcgccatg tacttcacct cggccacgta cgcgcgggag cagccggagg tggtgaagaa
    16021 gttccaggcg gccaccgccg agtccctcgc gtacgccgac gcgcaccccg acgaggtccg
    16081 cgagatcgtc accacgtaca cgaagatccc ggcggacgtg ctggcgaagg tgacgctgcc
    16141 gaagtggccg gccgagccca accgcgcggg tgtcgaggag ctggcgaggc tcggcgaggc
    16201 cgacgggctg ttcaagcggg cgccggacct ggacgagctg ctgccgtgag gggcgccgac
    16261 gccgcactgg gcgcggccgg gctcgcgggc ttcctcgccc tgggcgaggc ggtgccgcgg
    16321 ctcggcctgg tcgaggagga gtacttcccg cccaccagcc gcatcgccga cgcgctcggc
    16381 acggaggtcg cggacggcgc cttctggacc gcgctgggcg acaccctcac cggctgggcg
    16441 ctcggtctgg ccgtggcggt cggcgcgggg atcgtcgtgg gcgtgctgct gtccgtggtg
    16501 ccgtacctgc gcgaggcgac ggcgtccacg atcgagttcc tgcgccccat cccgtcggtc
    16561 gcgctgatcc cgctggcggt gctgctgttc ggcaccgaac tgcggtcggt gctgctcctg
    16621 gtcgtgtacg cctccttctg gcaggtgctg atccaggtcc tgtacggcgt gcgggacgtc
    16681 gatccggtcg ccgaggagac ggcacgctcg tacggcctgg gcgcctgggc gcggatccgg
    16741 tacgtgctgt ggccgaccgc gttgccgtac gtcatgaccg gggtgcggct ggcggcggcc
    16801 gtggcgctga tcctcgccgt caccgccgaa ctggtcgtcg gggcgccggg gctgggtgcc
    16861 cggatcgccg tggcgcagac ctcgcaggcc gtgcccgaga tgtacgcgct gatcgtcgtc
    16921 accggtctgc tgggcctgct gatcaacgtc ggcgcgcggt cggtggagcg gcgggcgctg
    16981 gcctggcacc agtcggtgcg cggggaggtg gcggtgtgag gcgcctgctg ctgcggctgg
    17041 tgttcgtgct cgccctgccg gtggtgctcg tggccgtctg gtgggttgcc tcgtcgggca
    17101 gcgaggacgt gtactggccg ccgctcggga cgatcgtgtc ggccttcccc gacgtgtgga
    17161 ccggcgagcg gtggcgcggt gacgtgctgc ccagcgtgct gcggctcgcc gccggctacg
    17221 cgctggcggg cgccgtcggt gtcgcgctcg gcacgctgat cggctcctac cggcgggtgc
    17281 gggcggtgtg cgagccggtg ctggagttcc tgcgggcggt gccgccgccg gtgctggtac
    17341 cggtgatcat gctgttcgcg ggcatcggcg acacgatgaa ggtcgtcgtc atcgcgagcg
    17401 gatgtgtctg gccggtgctg ctcaacacgg tcgagggggt gcgggcggtg gacgcggtga
    17461 cggccgagac ggcccgctcc tacggcatca cgggcgcggc gcggctgcgg cacgtggtgc
    17521 tgccctcggc gagtccgcag atcttcgcgg ggctgcgcca ggcgctgtcc gtcggcatca
    17581 tcctcatggt gatcagcgag atgttcgccg ccagcaacgg gctgggcttc accgtcgtgc
    17641 agttccagcg ttccttcgcg atccccgaca tgtggaccgg catcctgctg ctcggtctgc
    17701 tcggcttcgt gctgtcggtc ctcttccagc tggtcgagcg gcgggcgctc ggctggtacc
    17761 acggcctgcg cgccgcctcc cggcggtcac ggtgatgccg tgcccgacgg cgcgtgacgc
    17821 gcgttccgtg actcgtgctc ggtgaaaggg cggtccatgc tcgacgtacg cggcctgcgg
    17881 aaggtgtacg agggttcggg gcggcgggtc gaggcggtgc gcgatctgac cttctcggtg
    17941 gcggccggtg aactggtctg cctggtcggt ccgtcgggct gcggcaagac gacgctgctg
    18001 aagtgcgtgg gcgggctgct cgaaccgacg gcgggcgagg tgttcctggc cggccgcagg
    18061 gtgaccggtc cgccgcccgg gatggcgttc gtcttccagg agtacggacg cagcctgttc
    18121 ccgtggatgc gggtcggcga gaacgtcgaa ctgcccctga agcggaagga cctggccaag
    18181 gggcggcgcc gggagctggt cgcggacgcc ctggcgtcgg tcgggctcgc ggacgccgcg
    18241 ggggcctacc cgtggcagct gtccggcggt atgcagcagc gggtggccat cgcgcgggcg
    18301 ctggcgtacg agcccgaggt gctgctgatg gacgagccct tcgcggcggt ggacgcccag
    18361 acccgcgccg acctggagga cctggtgcgg gcgctgtggc gggagcgggg catcacggtc
    18421 ctgttcgtca cccacgacat cgacgaggcc gtgtacctgg ggcagcgggt gatcgtgctg
    18481 tccgcctcgc ccaccgtcgt acgcgagcag ctccgggtcg atctgccgga cgggcgggac
    18541 caggtgcaca cccgggtggc gccgcgcttc gcggagctgc gcacccgcgt gtacgagcag
    18601 atccaggcgg cgaagcgcgg ggcggcccga tccccgttca aggagccgca gggggcggac
    18661 acccctccgc cgcactgacc ccgggtcact cggcgacggg gacgaccctc aggtgggcgg
    18721 cggcgcggcg ggcgcgcggc gggcgctgcc cggtgcggcg cggctcgcgc aggaccagcg
    18781 tcagccgggt gtagcccagc tcctggagcg cccccggcgt ttcgaccacg acccggcact
    18841 cggtggtgcc ccggcgcggg tcggggtggt gcagcggccg taccgccccg tcgtgttcga
    18901 cggcgcgggc gccgacggcg cggacccagt gcggcaggcc ctggcggtag gcggcctcca
    18961 tgatcgggtc ctgggcgatg tcccggcgga cggcctgtag tccggggtcg tgaccgtacc
    19021 gctccagagt ggcggcgaag tgcgccagca tgggcaggca ccagctcgac tcgtgctcgc
    19081 cgaggaccgt ggcggcgtcc gggtggaaga ggacgaacct gaggaagttg tcgtcgggca
    19141 tggccgtcgg gtgcggtccg gcgccctgga agagtgtccg gaaggcgccg ttggccagca
    19201 ccacgtccca gcggtggtcg acgacgagag acgggaaggg cacggcctcg aggagcgcgg
    19261 tgtagtcctg gagataggcc tgggcctcgg gggtcgcggg ggtgggccgc ggcgccgacc
    19321 gctgccctcc tgcctgaaat gccatcggga ggtcacccct cttgcctatg cggccttctc
    19381 gcggcgtccc gcatcctggc gccccgacgc gaggcgtgtc aactatcgtg gcatttcgtg
    19441 cctgttgacg gctgaaatag gccacagttg tggcgatgcc tggatgtgag ttcgagcggc
    19501 aggctactct ccgggaagtt cacggcaact gcttgtgaga agcctgtgcg gcctgagaga
    19561 cgtaggagag ctgtcggtga cgggtggctt cgaaggtcag ggcgtcatgc cgacccctac
    19621 gccgaccacc acgccgaccg ccgtcgtcgc ccgggtcggc gcgctcgcgg accggctcgg
    19681 cgtgccgcac accgaggtct tcgacgtggg ccggctctcc gccgccagcg gcgtccccga
    19741 gtccgtcgtc ggggccctgc tcggcggccg gccggcgggt gagcccgatg tccagaccag
    19801 gttcgtgcag cgcctggacc tgctgcgccg cacccggctg aagccgaacg gccgcaagta
    19861 cacccagcag gagatcgccg acggcgccgg gatgtcccgg cagcaggccg gcgccctcat
    19921 caacggcgac cggcgcccca ccatggagca ctgcgacgcc attcagcgct tcttcggggt
    19981 gcacgccgga ttcctcaccg ccgaggaccc cgaagcgctc gccggtgccc tccagcgcac
    20041 cgagcaggaa ctgctccagc aactcgccga ccgggagcgg gaggcggcgg ccgccgccga
    20101 cgacccgctg gagcggctgc tccaggacca cggcgtgcgc ggcatcgcct ggcgggccgc
    20161 gcaactgccc acggaccagc accgcgacaa ggtcgccgag tggctggaca tgctcctgga
    20221 gagcgtcaag cggcccgagt cgtaacggca cggggcccac gggggcccgg cctgcggacg
    20281 ggattgtcag tggtgggcgg caagctggga gggtgccgcc gccgtgcggg ggcgcgtgac
    20341 cgctgacgtc gttgtgggga gagccgaccg atgaccaccg ccgtactgac cgaccacgag
    20401 cgcaccgccg tccaggccta cttgcggctc ctgcacaccg tacgggccgg tttcgacgcc
    20461 ggggcgggtc cggacgggcc tccccggccg cccgtcgtcc cgccctccgt gctggccgag
    20521 gcggaggagg ccctgcgggc ggcgggactg acggggaacg aggaggcgtt cttccggctg
    20581 ttgcgggact ggtgcccgcg gccctgaggg gaggcgggcg gcgtctggtg acccctcagg
    20641 tgcgcgggac cgcgacggcc gtggtgacca ggccctcccg ggcggtccag cggccgtcga
    20701 agtggctcag gcgcctgccc cccacggtcg gtccgggcac caggagcgcg gcgtgcagcg
    20761 tgccgcggcg cgggtcggcc gggtccacgg agatctcgat gtccgcctcg gcgaagtcca
    20821 gccacttccc ggtgaggggg aaccacgcct tgtagaccga ctccttcgcg ctgaacagca
    20881 gccggtccca gtggacgtcg ggccgcgcct cgtccagccg ccgcagtcgg gccgtctcgg
    20941 aggacagagc gatggtcttg aggacgccgt ccgggagcgg tccgtcgggt tcggcgtcga
    21001 tgccgaggga ggccaggtcg gtcacgcgga ccagggcggc ggcgcagtag ccgtcgcagt
    21061 gggtcatgct gccggtgaga ccgtccggcc agcgcggggc cccgcgctcc ccggtcagca
    21121 cgggctgcgc gggtacgccg agcttctcca tggcccggcg ggcgcaggac cgcaccacgg
    21181 tgaactcccg gcgccgcttg gcgaccgccc gcgcgacgag ctcctcctcc tcggggtaga
    21241 ggggcaggtg gccggcgtcg tcgtgtccga acgcctccac ggtgacgacc gtgtcgggca
    21301 gcaggtcctc gatcaacggg acacctcctg gcgagaaggc gccgcgggcg cctgttccga
    21361 cggcaggatg cggcgcagtc gccccggcgg cccggaccgc ttgcgccact cgcggggata
    21421 gcccaccgac acctcctcga agcggacccc ctcgtgccag gtggtgcgcg ggatgtgcag
    21481 gtgcccgtag accatggtgt cgacccggaa cctgcggtgc cagtcggcgg tcagcgcggt
    21541 gccgcaccac atggcgaact cggggtacca caggacgtcg gtgggatgcc ggtgcagcgg
    21601 atagtggttg acggggatga tcggcaggtc cgcggggatc tcggcgagcc tgcgcccggt
    21661 ctcctcgacc cgggcccggc accacgcctc acggctggga taggggtcgg ggtgcagcag
    21721 gtactcgtcg ctgcacacga cgccggtgcc gtgcgcgtac tccagtccct cggccttgtt
    21781 cgcgcagccc gcgggcagga acgagtagtc gtacagcagg aagagcggcg cgacgaccgc
    21841 cgggccgccc gcgccctccc acaccgggta cgggtcctcg ggggtggtca cgcccagttc
    21901 ccggcacatc tcgacgaggt gccggtagcg ggcgacgccg cgcagggcga ccgcgtcctt
    21961 gggatgcgtc cacagttcgt ggttgcccgg gacccagacg acccggcgga agcggtccgc
    22021 gagggtgccg agcgcccagc ggatgtcggc gacggtctcc gccacgtcgc cggccaccag
    22081 gagccagtcg tcgtcggact cggggcgcat ccgctcgacc agggtccggt tctccttgta
    22141 tccgatgtgc agatcgctga tggcccacag cttccccgga gcgccggccc tcgacgtcat
    22201 cccccacccc ttccagacac gcgtccgacg ccacgagatc acatccccgc cccggtcaca
    22261 aggcggcctc cgggccccgc cgcgccgggg cccgggggcc ccgggacggc cggtccggcg
    22321 catccgtgtg acgcgcgttg cgcccggggc ggcgcgtacc cctatgatcg ccccaacacc
    22381 accgcgacga ctctcctttc gcgcagagcg gcggctcggt gtccctccaa acccctggcc
    22441 gggcacggcc cgcttcggcc tgcccgcgaa ccccggaagg cggcttgcat ggcttctccc
    22501 gtacgcgtct ggctcaaccg cacgtacgcg gagaacgtct tcttcatgga tcagctgcgg
    22561 agaaatcccg ccgaccgggc cgtcgagatc catgccacgc acggcgaccc ggactccccc
    22621 gtgctggccg ccgcggacac cgccgacctg gagccggagg gcctgtcccc cgccgggtac
    22681 gtcgagtacg cgctggacca gtgcgcgcgg cgcggcatcg acgtgttcgt
//
