LOCUS       NZ_KZ195583            29821 bp    DNA     linear   CON 07-SEP-2024
DEFINITION  Streptomyces sp. CS227 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ195583
VERSION     NZ_KZ195583.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS227
  ORGANISM  Streptomyces sp. CS227
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6794013)
  AUTHORS   Malmierca,M.G., Gonzalez-Montes,L., Perez-Victoria,I., Sialer,C.,
            Brana,A.F., Garcia Salcedo,R., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Searching for Glycosylated Natural Products in Actinomycetes and
            Identification of Novel Macrolactams and Angucyclines
  JOURNAL   Front Microbiol 9, 39 (2018)
   PUBMED   29441046
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6794013)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Searching for glycosylated natural products in actinomycetes
            isolated from leaf-cutting ants: activation of two silent clusters
            and identification of a novel macrolactam
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 6794013)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAY-2017) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 370.61x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002188355.1-RS_2024_09_07
            Annotation Date                   :: 09/07/2024 02:15:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,017
            CDSs (total)                      :: 5,954
            Genes (coding)                    :: 5,785
            CDSs (with protein)               :: 5,785
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1 (5S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 169
            CDSs (without protein)            :: 169
            Pseudo Genes (ambiguous residues) :: 0 of 169
            Pseudo Genes (frameshifted)       :: 72 of 169
            Pseudo Genes (incomplete)         :: 127 of 169
            Pseudo Genes (internal stop)      :: 12 of 169
            Pseudo Genes (multiple problems)  :: 41 of 169
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:26:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4699444
            Orig. end                         :: 4729265
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ195583.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Salas's laboratory, A.
            Microbiology, University of Oviedo, Spain.
FEATURES             Location/Qualifiers
     region          1..29821
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="18"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..29821
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..29821
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:15821](-)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(14001..15821)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     misc_feature    complement(449..462)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            complement(735..1781)
                     /locus_tag="B9W68_RS20980"
                     /old_locus_tag="B9W68_21030"
     CDS             complement(735..1781)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018468241.1"
                     /locus_tag="B9W68_RS20980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21030"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_047465049.1"
                     /transl_table=11
                     /translation="MASEFSAAAPSSVEEGAAAPASGVAVAAGPPQDPGREAADRRRER
                     RSRWYRRDVKWSPYAFIAPFFLFFAAFGLFPLLYTGWASLHRVELTAPNDMEWIGLRNY
                     TRLLDDEFFWNALQNTFTIGILSTVPQLLMALGIAHLLNYRLRGSMFFRVAALTPYATS
                     VAAATLVFVMLFGRDYGMINWFLSLAGFEHIDWQNGSFTSQLAVSSIVVWRWTGYNALI
                     YLAAMQSIPSDLYESAALDGASRWQQFLHVTLPSLRPTILFTVVVSTIGAIQLFGEPLL
                     FNGGGGATGGSDHQFQTLGLYLYEQGWTNLHLGRASAIAWAMFLLLIVIGLVSLAVTRW
                     LRRGEGKA"
     gene            complement(1788..3116)
                     /locus_tag="B9W68_RS20985"
                     /old_locus_tag="B9W68_21035"
     CDS             complement(1788..3116)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003983266.1"
                     /locus_tag="B9W68_RS20985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21035"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_087775356.1"
                     /transl_table=11
                     /translation="MRTRSRTARKAVVLAAVAALGTSLLAGCASDDEPKAAGNEAGSDK
                     GKTTLTVGVFGAFGLKEAGLYDQYMKENKDVVIKQTSIERNENYYPQLLTHLGTSSGLA
                     DIQAVEVNNIAEIVQTQGDKLEDLSKAPGVEKDAFLKWKWDQGTTQAGKTVALGTDIGP
                     QGICYRKDLFEKAGLPTDREEVGKLWAGDWNKYLEAGKEFQKNAPKGAKFVDGAPGVMA
                     AVTGSSANRYYDDKGEVVYKSNPAVKEAWDLAAEFASEGLTAKLQQFTDGWNKAFSNGT
                     FATVSCPAWMLGYIQDKGGEKNADKWDVAQAPKPGNWGGAFLTVPSAGKNKEEAAKLAA
                     WLTAPEQQAKFFAERGSFPSAQAAYDLPEIADANHEYFDDAPIGKIFAEAAKGAPVQIL
                     GPKDLVIAQNLADVGMLQVDQKGKSSEEGWKAAVKAIDNALDQ"
     misc_feature    complement(3230..3244)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.65"
                     /tool="antismash"
     misc_feature    3231..3245
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.65"
                     /tool="antismash"
     misc_feature    3314..3331
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.45"
                     /tool="antismash"
     gene            3390..4445
                     /locus_tag="B9W68_RS20990"
                     /old_locus_tag="B9W68_21040"
     CDS             3390..4445
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010638131.1"
                     /locus_tag="B9W68_RS20990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21040"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_087775359.1"
                     /transl_table=11
                     /translation="MTAGRSNGRSGGRPTLEEVAARAGVGRGTVSRVINGSPRVSETTR
                     AAVEAAVAELGYVPNTAARALAANRTDAIALVVPEPETRFFTEPYFSDILSGIGAALAP
                     TDLQLLLTFADGARERRRLAQYLAAHRVDGVLLVSVHADDPLPDLLSQLEIPAVISGRR
                     SEDEPLASVDTDNYSGARAAVTHLLERGRTTIATISGRLDVYGAQRRLDGYRSALGDAG
                     RHPEDSLVAAGDFTEEGGRQAMRLLLGRHPELDAVFACSDVMAAGALQVLREAGRRIPE
                     DVALVGFDDSAVARLMDPPLTSVRQPTAAMGRAMTEALLAEIAEGRPDSSRLRRPRQVV
                     LDTELVVRAST"
     gene            4534..4761
                     /locus_tag="B9W68_RS20995"
                     /old_locus_tag="B9W68_21045"
     CDS             4534..4761
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948199.1"
                     /locus_tag="B9W68_RS20995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21045"
                     /product="hypothetical protein"
                     /protein_id="WP_087775362.1"
                     /transl_table=11
                     /translation="MELPDYLIRLQRAADDEGRRLEHLDEDERDAARRRYFNAAAEVDV
                     AVRDFAASAGLDRHTVEKELRQQARQPPTD"
     gene            4802..4972
                     /locus_tag="B9W68_RS31120"
     CDS             4802..4972
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018468238.1"
                     /locus_tag="B9W68_RS31120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_179230585.1"
                     /transl_table=11
                     /translation="MNTRTDTAPRPAAVVNAEIRALLMRRGGLAPAERAAYERLLVEWA
                     EAVRAEVVVAA"
     gene            5042..5671
                     /locus_tag="B9W68_RS21000"
                     /old_locus_tag="B9W68_21050"
     CDS             5042..5671
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9W68_RS21000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B9W68_21050"
                     /product="hypothetical protein"
                     /protein_id="WP_143665345.1"
                     /transl_table=11
                     /translation="MTRWKRQRKRQKSGRGALPAALMAAALLATGCGAADTGGPAPHPG
                     LDAFHAQECPELTASEKENGNLLTLAHDQPEVGVSLRPGGAPATVLVKLCNTTDRPLTD
                     IALSIQLEWSDAGERDPRLKVEHRETPDGRWRSAELVVANDYQPLRGADAARDLAPGAT
                     RVVEYRFSAAEDAPSGARPLMIQAVRADEQRGGGLAGLRLSVLPSD"
     gene            complement(5856..6506)
                     /locus_tag="B9W68_RS21005"
                     /old_locus_tag="B9W68_21055"
     CDS             complement(5856..6506)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948197.1"
                     /locus_tag="B9W68_RS21005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21055"
                     /product="endonuclease"
                     /protein_id="WP_087775368.1"
                     /transl_table=11
                     /translation="MSASQSAVAATLLDRHGTTYAREAGITLKDTPQPLYQLLVLSSLL
                     SARIRASVAVAAARALFQDGMRNPRAMADASWQERVDALGEGGYRRYDERTATQLGDGA
                     ELLLDEHRGDLRQLREKADGDEQTLVQGLQETPGMGPAGAGIFLREAQAVWPEYAPHFD
                     GKALQGAERLGLPQDPKRLARLAGDAGPAVLAAALVRAALEKKVADDVLEHAG"
     tRNA            complement(6657..6729)
                     /anticodon=(pos:complement(4706138..4706140),aa:His,
                     seq:gtg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="B9W68_RS21010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="B9W68_21060"
                     /product="tRNA-His"
     gene            complement(6657..6729)
                     /locus_tag="B9W68_RS21010"
                     /old_locus_tag="B9W68_21060"
     misc_feature    6757..6768
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.87"
                     /tool="antismash"
     misc_feature    6758..6776
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.23"
                     /tool="antismash"
     gene            complement(6821..7423)
                     /gene="orn"
                     /locus_tag="B9W68_RS21015"
                     /old_locus_tag="B9W68_21065"
     CDS             complement(6821..7423)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0000175 - 3'-5'-RNA exonuclease activity
                     [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="orn"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948196.1"
                     /locus_tag="B9W68_RS21015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21065"
                     /product="oligoribonuclease"
                     /protein_id="WP_087775371.1"
                     /transl_table=11
                     /translation="MNDRMVWIDCEMTGLSLADDALIEVAALVTDSELNVLGDGVDIVI
                     RPPDEALETMPEVVRKMHTASGLLAELAEGTTLADAEARVLAYVREHVKEPGKAPLCGN
                     SVGTDRNFLARDMAALEGYLHYRIVDVSSVKELARRWYPRAYFNSPDKNGNHRALADIR
                     ESIAELRYYREAIFVPQPGPDSDTAKAIAAQHVLTSE"
     gene            complement(7529..8749)
                     /locus_tag="B9W68_RS21020"
                     /old_locus_tag="B9W68_21070"
     CDS             complement(7529..8749)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948195.1"
                     /locus_tag="B9W68_RS21020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21070"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_087775373.1"
                     /transl_table=11
                     /translation="MSHDSTVTADLAGRKLSGRRRKEIVAVLLFSGGPIFESSIPLSVF
                     GIDRQDAGVPRYRLLVCAGEDGPLRTTGGLELTAPQGLEALARAGTVVVPAWRSITSPP
                     PAAALDALRRAHEEGARIVGLCTGAFVLAAAGLLDGRPATTHWMYAPTLAKRYPSVHVD
                     PRELFVDDGDVLTSAGTAAGIDLCLHVVRTDHGSEAAGALARRLVVPPRRAGGQERYLD
                     RSLPEEIGADPLAEVVAWALEHLHEQFDVETLAARAYMSRRTFDRRFRSLTGSAPLQWL
                     ITQRVLQAQRLLETSDYSVDEVAGRCGFRSPVALRGHFRRQLGSSPAAYRAAYRARRPQ
                     QEQQRPEPVQPTQPVQVFDGPLPPQLRRTPQGVGAHHGDPGRGAPDAYLQGRAALPGQR
                     ERPLGGV"
     misc_feature    complement(8075..8077)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(8946..8959)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     misc_feature    9013..9031
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.75"
                     /tool="antismash"
     misc_feature    9014..9030
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.87"
                     /tool="antismash"
     misc_feature    complement(9098..9112)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.1"
                     /tool="antismash"
     gene            complement(9198..9608)
                     /locus_tag="B9W68_RS31940"
     CDS             complement(9198..9608)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9W68_RS31940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_256968435.1"
                     /transl_table=11
                     /translation="MPVPHVSGPDPATLLPRPTPARAPERGSRAPGAACAGARAPRGLP
                     GARTAPGAASAPAASTAARGAGPAPVSTAARWAAFGCVLAPVVLVVYGAAAGGVMWVAP
                     VLTAVTGICRLLLRRAERGAAGARCAAGDVPR"
     misc_feature    9722..9736
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.84"
                     /tool="antismash"
     gene            10133..10657
                     /locus_tag="B9W68_RS21030"
                     /old_locus_tag="B9W68_21080"
     CDS             10133..10657
                     /GO_function="GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019325548.1"
                     /locus_tag="B9W68_RS21030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21080"
                     /product="universal stress protein"
                     /protein_id="WP_030697238.1"
                     /transl_table=11
                     /translation="MAGHESFESADRKRQVADPSAQPLAAEETRQPCDPAFRHGVVVGF
                     DGSTSSERALAYAIGMARRSGSGLIIVHVANRLPTTVWAGCEPPVFVDVPDHRTEVLGL
                     ELACAEYLGDVSWILVERGGDICHELEEVGTEYEADAIVVGSSQGVVGRLFGSVAGRLA
                     RRARRPVVVIP"
     gene            complement(10692..12521)
                     /gene="glmS"
                     /locus_tag="B9W68_RS21035"
                     /old_locus_tag="B9W68_21085"
     CDS             complement(10692..12521)
                     /EC_number="2.6.1.16"
                     /GO_function="GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA]"
                     /GO_process="GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="glmS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980526.1"
                     /locus_tag="B9W68_RS21035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21085"
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="WP_003948192.1"
                     /sec_met_domain="GATase_7 (E-value: 2.1e-13, bitscore:
                     48.7, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIVGYIGRRDDVAPLLLEGLQRLEYRGYDSAGIAIHGKSGSKS
                     TGLKSVKAKGRVRDLEARVPARFKGSVGIAHTRWATHGAPNDENAHPHLDADSKVAVVH
                     NGIFDNASDLRARLTADGVVFLSETDTEVLAHLIGRSEADTLEGKVREAVGQIEGTYGV
                     AVLHADFPDRIVVARNGSPVVLGIGEKEMFVASDVAALVSHTRQVVTLDDGEMATLKAD
                     DFRTYTTEGSRTSATPTTVEYEAESWDMGGHDTYMHKEIFEQAEAVDRVLRGRIDDRFS
                     TVHLGGLNLDAREARGVRRIKILGCGTSYHAGQIGAQLIEELARIPADAEPASEFRYRN
                     PVVDPDTLYIAVSQSGETYDVLAAVQELKRKGARVLGVVNVVGSAIAREADGGLYVHAG
                     PEVCVVSTKCFTNTVVAFGLLALHLGRTRDLSVADGKRIIAGLRKLPEQIADILSREDE
                     IEKLAEEFTEARSMLFIGRVRGYPVAREASLKLKEVSYIHAEAYPASELKHGPLALIEP
                     AMPTVAIVPDDDLLEKNRAALEEIKAREGKILAVAHREQEKADHTIVVPKNEDELDPIL
                     MGIPLQLLAYHTALKLGRDIDKPRNLAKSVTVE"
     misc_feature    complement(12551..12565)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.09"
                     /tool="antismash"
     gene            complement(12612..12887)
                     /locus_tag="B9W68_RS21040"
                     /old_locus_tag="B9W68_21090"
     CDS             complement(12612..12887)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608703.1"
                     /locus_tag="B9W68_RS21040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21090"
                     /product="hypothetical protein"
                     /protein_id="WP_003948191.1"
                     /transl_table=11
                     /translation="MLERRTNHDDLVDHLVRTTPLSRGEAGRVVMDVLAYFDETTEECV
                     RRRHRELQAQGLGNTEIFERIAEELPRRAVAPPALSLRQLRRIVYG"
     misc_feature    complement(12838..12853)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 20.91"
                     /tool="antismash"
     gene            complement(13007..13915)
                     /locus_tag="B9W68_RS21045"
                     /old_locus_tag="B9W68_21095"
     CDS             complement(13007..13915)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010638121.1"
                     /locus_tag="B9W68_RS21045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21095"
                     /product="DUF4429 domain-containing protein"
                     /protein_id="WP_087775376.1"
                     /transl_table=11
                     /translation="MAEITQRDGSWSYEDRRIRIVPGAKAHPVRQVLGEVVVPLTAVAG
                     ITFERDRKGGRLRLRLRDGACPVVRAAEGRLPEGADPYRLVVESGREDLAEYVVAEVRQ
                     ALLLEQIPEGPVERFLLPGPALPVSGGGGDGTAAFDGREVRLTWNWKGKETKTSAGPTT
                     LALADLTGVSWVPAQGLENGHLRFLTRSGGGKTVAPEHDPHALDLWGLSKKEHTAVLVA
                     AAVLVALAARGEPERTPGALDKAEVPAQLPLPSAPAPQAGAADDPDALLRRLRELGELH
                     RDGVLTDEEFSLAKQAVLRRL"
     misc_feature    13892..13905
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.65"
                     /tool="antismash"
     gene            complement(14001..15821)
                     /locus_tag="B9W68_RS21050"
                     /old_locus_tag="B9W68_21100"
     CDS             complement(14001..15821)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008407742.1"
                     /locus_tag="B9W68_RS21050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21100"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_087775379.1"
                     /sec_met_domain="IucA_IucC (E-value: 5.6e-78, bitscore:
                     260.3, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDTTPTEQLAAPTAHLTPELWAAAGRHLVRKGLAEFSHERLLTP
                     EPLPGAEPDAEGRTAHRVVTDDGVTEYRFAAKLLSLDHWDIAADSITRHGEGGTELPLD
                     ALDFILDTRTALGIGDAILPVYLEEISSTLSGAAWKLAQARPSAAELARAGFQAIETGM
                     TEGHPCFVANNGRIGFDVREYHQYAPETASPVRLLWLAARRDRSTFTSGAGLDYDTLVK
                     GELDPATLARFAATLEGQGLDLADYHLLPVHPWQWWNKLSVSFAAEVAQQRLVLLGEGD
                     DAYLAQQSIRTFFNTSHPDKHYVKTAMSVLNMGFMRGLSAAYMEATPAINDWLAQLIAG
                     DEVFRAARFSIIRERAAIGYHHRQYERATDRYSPYRKMLAALWRESPVPQLGEGQRLAT
                     MASLLHTDADGASLAGALIAESGLAPEVWLRRYLDAYLVPVLHSFYQYDLVYMPHGENV
                     ILVIEDGAVDRVIFKDIAEEICVMDPDAVLPPAVERIKAEVPEEMKILSIFTDVFDCYL
                     RFLNATLAGEGVLDEDTFWRTAAESVRAYQESMPQLADRFAQYDMFAPTFALSCLNRLQ
                     LRDNQQMVDLADPSGALQLVGDLVNPLAGR"
     gene            complement(15818..16423)
                     /locus_tag="B9W68_RS21055"
                     /old_locus_tag="B9W68_21105"
     CDS             complement(15818..16423)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008407740.1"
                     /locus_tag="B9W68_RS21055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21105"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_087775382.1"
                     /transl_table=11
                     /translation="MTTPRTAKVRPDRLAIRPLDLDADAGLVHGWVTHPKSAFWLMQGL
                     SVDEVRGEYASIAAHPHHDAFIGLYEDSPAFLMERYDPAHVELVGLYDPEPGDVGMHFL
                     CAPTDTPLHGFTRAVIFAVMEYLFADPDTVRVVVEPDVRNAAVHALNEAVGFEIARKIA
                     KPEKEAYLSVCTRDAFEAAKKAAATVPAGDDTKEQAPR"
     gene            complement(16420..17730)
                     /locus_tag="B9W68_RS21060"
                     /old_locus_tag="B9W68_21110"
     CDS             complement(16420..17730)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080: lysine/ornithine N-monooxygenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948187.1"
                     /locus_tag="B9W68_RS21060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21110"
                     /product="lysine N(6)-hydroxylase/L-ornithine
                     N(5)-oxygenase family protein"
                     /protein_id="WP_087775385.1"
                     /transl_table=11
                     /translation="MSTPLERSSRTASDSAEPLDLLGIGLGPFNLGLACLAEPLDEIDA
                     LFLETKPDFDWHSGMFLDGAHLQTPFMSDLVTLADPTSPYSFLNYLKESGRLYSFYIRE
                     NFYPLRTEYNDYCRWAAARLGSVRFSTTVTEVTYDEENALYTVTTDQGDTYRARHLALG
                     TGTPPHIPEPCQGLGGDLLHNSRYLEHKAALQAKKSITLVGSGQSAAEIYHDLLAEIDV
                     HGYQLNWVTRSPRFFPLEYTKLTLEMTSPEYIDYFHALPEDTRYGLEQKQKNLFKGIDG
                     ELINAIFDLLYEKSVRGPVPTRLLTNTALQTAAWDESEGTYTLGLRQEEQGKDSVLSSE
                     GLVLATGYQYRVPDFLQPVRDRIRWDGRGRFDIARNYSIDTTGRGIFVQNAGVHTHALT
                     SPDLGMGAYRNSVILRELLGTAPYAVEKSIAFQEFSV"
     gene            complement(17714..19171)
                     /locus_tag="B9W68_RS21065"
                     /old_locus_tag="B9W68_21115"
     CDS             complement(17714..19171)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018894987.1"
                     /locus_tag="B9W68_RS21065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21115"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_087775388.1"
                     /transl_table=11
                     /translation="MSLLAPRSHLLNDLNVEAYRRSVTEGVERVAASLTGATSPFTGVT
                     PAALAPVVDAVDLDRPLGDTAAALDELTDVYLRDAVYFHHPRYLAHLNCPVVIPAVLGE
                     AVLSAVNSSLDTWDQSAGGTLIERRLIDWTAGRIGLGGGADGVFTSGGSQSNLQAMLLA
                     REEAKAAHPTQLRVFTSDVSHFSVRKSATLLGLGPDAVVTIPTDRERRMRIEVLAAELR
                     RCEAEGLVPMAVVGTAGTTDFGSIDPLPEIAELCARHNTWMHVDAAYGCGLLVSPTRRA
                     LLTGIEHADSVTVDYHKSFFQPVSSSALLVRDGATLRHATYHADYLNPRRAAEERIPNQ
                     VDKSLQTTRRFDALKLWMTLRVMGADGVGQLFDEVCDLAGEGWKLLVADPRFDVVVEPS
                     LSTLVFRYLPGQPTDPAQIDRANLYARKALFASGDAVVAGTKVDGRHYLKFTLLNPETK
                     ASDIAAVLDLIAGHAEQYLGESLVHAS"
     misc_feature    complement(19239..19257)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 36.53"
                     /tool="antismash"
     gene            complement(19506..20372)
                     /locus_tag="B9W68_RS21070"
                     /old_locus_tag="B9W68_21120"
     CDS             complement(19506..20372)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1200: vibriobactin
                     utilization protein ViuB"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018468230.1"
                     /locus_tag="B9W68_RS21070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21120"
                     /product="siderophore-interacting protein"
                     /protein_id="WP_087775391.1"
                     /transl_table=11
                     /translation="MTTTPTAPVRTPFRFFDVEVRGSRRLSPSLVRLTFGGEELALFES
                     GGRDQSCSLFLPHPGQRVPRVPIEAGEDWWAAYRAMPEEERAVMRSYTVRAQRRADDGT
                     TEFDVDFALHGDTGPACRWAARALPGDRIVVLGPAVTENVSVRFRPPGSAAWALMWADL
                     TSLPATEAILEWLPAGFPVRLWIEVPHAEDRRELATAADAEITWLVADEGAPSAAEAVR
                     AAELPAGEPYAWIAGEAGRMRTLRRHLVGERGFDRRAVTFVGYWREGASEEQLRAESLT
                     TGKRRTA"
     misc_feature    complement(20406..20424)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 31.62"
                     /tool="antismash"
     gene            complement(20471..21097)
                     /locus_tag="B9W68_RS21075"
                     /old_locus_tag="B9W68_21125"
     CDS             complement(20471..21097)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008407728.1"
                     /locus_tag="B9W68_RS21075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21125"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_087775394.1"
                     /transl_table=11
                     /translation="MAEEKDGRRVGRPPLTERRKAATRLEIAREAVRLFAAQGVAATTA
                     DEIAAAAGISPRTLWRYCSSKEECVGPLLTTALDAAAERLTSWPRERTLTDGISAHPPG
                     RSATALAEDEQALRDLVRLVRTEPGLRAVWLQVHHAAEPVLARVFAARTGLSPDALEPR
                     VQAALLNTALRVAVEEWAWNTAPGTGTPGEAITEVLAIAEAGLPR"
     gene            21254..22021
                     /locus_tag="B9W68_RS21080"
                     /old_locus_tag="B9W68_21130"
     CDS             21254..22021
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (11-177). E-value: 1.7e-09.
                     Score: 29.8. Matches aSDomain:
                     nrpspksdomains_B9W68_RS21080_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948181.1"
                     /locus_tag="B9W68_RS21080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21130"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_087775397.1"
                     /sec_met_domain="adh_short (E-value: 4.2e-35, bitscore:
                     119.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTTGLAGRAVVVTGAGSGIGRAAALRFAAEGAKVLLADLNGEA
                     AEAAAREIAEAGGTAVTVTGDLSDQAVVDQVVATAVERFGSLDVLVNNAGIMDRMSAAG
                     ETEDAEWERVVRVNLTAPFLLTRAALPHLLATGKGAIVFTASEASLRGSAAGAAYTASK
                     HGVAGLTKSVAVMYREKGLRANAIAPGGTATNIQVDADGEAHGPAVLGSYVRNVGSPAQ
                     AEEQAAAIVFLASDAASNINGVILPVDGGWAAV"
     CDS_motif       21287..21427
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B9W68_RS21080_0001"
                     /evalue="8.40E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="B9W68_RS21080"
                     /protein_end="58"
                     /protein_start="11"
                     /score="12.0"
                     /tool="antismash"
                     /translation="VVVTGAGSGIGRAAALRFAAEGAKVLLADLNGEAAEAAAREIAEA
                     GG"
     aSDomain        21287..21784
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9W68_RS21080_PKS_KR.1"
                     /evalue="1.70E-09"
                     /label="B9W68_RS21080_PKS_KR.1"
                     /locus_tag="B9W68_RS21080"
                     /protein_end="177"
                     /protein_start="11"
                     /score="29.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVTGAGSGIGRAAALRFAAEGAKVLLADLNGEAAEAAAREIAEA
                     GGTAVTVTGDLSDQAVVDQVVATAVERFGSLDVLVNNAGIMDRMSAAGETEDAEWERVV
                     RVNLTAPFLLTRAALPHLLATGKGAIVFTASEASLRGSAAGAAYTASKHGVAGLTKSVA
                     VMY"
     gene            22108..22545
                     /locus_tag="B9W68_RS21085"
                     /old_locus_tag="B9W68_21135"
     CDS             22108..22545
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010638101.1"
                     /locus_tag="B9W68_RS21085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21135"
                     /product="SgcJ/EcaC family oxidoreductase"
                     /protein_id="WP_087775400.1"
                     /transl_table=11
                     /translation="MNQDEEQIRRLIEEWASAVHRGDLATVVRDHADDLVMYDVPPPYE
                     GLRGLDAYRAVWPGFFAWQASGAEFTLDTLDVTAGQDVAYAHALLRCGTPEELAEHPAL
                     RLRLTLGLRKENGRWVVAHEHHSFPDLSSPPESSSSAGRAS"
     gene            complement(22875..23492)
                     /locus_tag="B9W68_RS21095"
                     /old_locus_tag="B9W68_21145"
     CDS             complement(22875..23492)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018468224.1"
                     /locus_tag="B9W68_RS21095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21145"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_256968436.1"
                     /transl_table=11
                     /translation="MTADASTRQRLLAAAKQLFLEKGADQVSLRAVNAAAGLNPGAVHY
                     HFGSREGLVSALLEQELGPVWNSRWAASSEGRATGLQEVRRLVEGLVEPFADLVATRDG
                     RVLCHLLARTALPSGQLPHVPTALTPAPFEVRVGRALPELSPREVSERCALAFTLVMET
                     YGRPTAKGPAENASFPATATVTAFVLAGLTAPPVPDEPGGSA"
     gene            23628..24455
                     /locus_tag="B9W68_RS21100"
                     /old_locus_tag="B9W68_21150"
     CDS             23628..24455
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049492.1"
                     /locus_tag="B9W68_RS21100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21150"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_087775406.1"
                     /transl_table=11
                     /translation="MGTYAVTGSASGMGAASAARLREAGHRVVGVDLRDADVTADLGTA
                     GGRRHAADEILRLCDGALDGVAAVAGVGPNLPDAAAVASINYFGPVALLDALRPALERN
                     GGGRAVVIGSNSATTVPMIDDHLVGLLLAGDEEAARTHAAGAQRSLPAELAATSPSISA
                     YATSKFALARWVRRTAVTPEWARRGITLNTLAPGAVVTPLMTGSTMSEDDLDPDAFPTP
                     MPRGIFGRPADIAFWVAQFLSPEAGFTTGATLTVDGGTDAALRPDAQPTAMPR"
     gene            24508..25737
                     /locus_tag="B9W68_RS21105"
                     /old_locus_tag="B9W68_21155"
     CDS             24508..25737
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010638092.1"
                     /locus_tag="B9W68_RS21105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21155"
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="WP_087775409.1"
                     /transl_table=11
                     /translation="MQPRTTPSAFPPASPPTSPPALFEPARLGPLTLRNRFIKAATFEG
                     MTPGALVSDELIDFHRRHAAGGVALTTVAYCAVAPDGRTERDQIWMRPEALPGLRRLTD
                     AVHAEGAAASAQIGHAGPVADGRSNGLPAVSSSPNFNPRSLGVIRQASRQDIARITRGH
                     AEAARLAVEAGFDAVEIHLGHNYFASSFLSPKLNKRKDEYGGSLAHRARVARDAARAVR
                     EAVGDRIAILAKLNMDDGVPGGLWLDESLQVAQWLQADGSVDALELTAGSSLLNPMYLF
                     RGDAPVREFAAAMRNPLVKQGVKAVGKHFIRAYPYQEAYLLDSARQFRAAVDLPLVLLG
                     GVSRRETAEQAMAEGFPFVAMARALLREPDLIRRMRDDATTRSLCIHCNKCMPTIFSGT
                     HCPLATPSAP"
     gene            25825..26415
                     /locus_tag="B9W68_RS21110"
                     /old_locus_tag="B9W68_21160"
     CDS             25825..26415
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018894980.1"
                     /locus_tag="B9W68_RS21110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21160"
                     /product="hypothetical protein"
                     /protein_id="WP_087775412.1"
                     /transl_table=11
                     /translation="MDQGGQATPAVDRTVTYQEDPPRTWTRICLAAYALWAVYQAFQLL
                     PDELTAWLVVCAMSLLLLLCLLAVPLSKRLYHRIRLADGELRVGRERLAVASLSPVSLT
                     AAAGEPGRAGLREYRASLTPDQLKEARRRTNALTRPRLVGGAWAVPVGMEELVVETVEG
                     ASLVLATRDRAGLLGALTRARGSDPSPRGNVRR"
     gene            26784..27176
                     /locus_tag="B9W68_RS21115"
                     /old_locus_tag="B9W68_21165"
     CDS             26784..27176
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B9W68_RS21115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="B9W68_21165"
                     /product="hypothetical protein"
                     /protein_id="WP_256968437.1"
                     /transl_table=11
                     /translation="MTFSGWPFGGKPSLAFGQLTVAGESVPLRRDRWALSRQGRALRFE
                     VAGRAYRYYATSRRHRHRALAREGVEIVTHRPRRGEGKSATVSVRGPADATDVALAVLL
                     CGVNTRNLTPGGAVRTFFYRVFSQLA"
     gene            complement(27186..28361)
                     /locus_tag="B9W68_RS21120"
                     /old_locus_tag="B9W68_21170"
     CDS             complement(27186..28361)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507859.1"
                     /locus_tag="B9W68_RS21120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21170"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_030697255.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 9.9e-38, bitscore:
                     127.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 7.8e-21, bitscore:
                     72.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.1e-48, bitscore:
                     162.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLDHRLSAEHEELRRTVEAFAHDVIAPKIGDLYERHEFPYEIVR
                     EMGRMGLFGLPFPEEYGGMGGDYLALGIALEELARVDSSVAITLEAGVSLGAMPIHLFG
                     TEEQKRAWLPRLCSGEILGAFGLTEPGAGSDAGGTRTTARLDEATNEWVINGGKCFITN
                     SGTDITGLVTVTAVTGRKPDGSPLISAIIVPSGTPGFTVAAPYSKVGWNASDTRELSFD
                     EVRVPAANLLGEEGRGYAQFLRILDEGRIAIAALGTGLAQGCVDESVKYAAERHAFGKP
                     IGANQAIQFKIADMDTRAYTARLAWRDAASRLVAGEPFKKQAAAAKLYSSTVAVDNARD
                     ATQIHGGYGFMNEYPVARMWRDSKILEIGEGTSEVQRMLIARELGVGGGRG"
     gene            complement(28421..29398)
                     /locus_tag="B9W68_RS21125"
                     /old_locus_tag="B9W68_21175"
     CDS             complement(28421..29398)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948168.1"
                     /locus_tag="B9W68_RS21125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_21175"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_087775417.1"
                     /sec_met_domain="HMGL-like (E-value: 6.2e-47, bitscore:
                     158.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASPTPGTGPGVPGLPMVVRADGLPSRVRIHEVGPRDGLQNEKT
                     VVPTEVKAEFVRRLAAAGLTTVEATSFVRPEWVPQLADAEQLFPMLDEVREAGTDLPVL
                     VPNARGLDRALALGARHVAVFASATETFARRNLNRTVAESLAMFEPVVTRAKAEGLRVR
                     GYLSMCFGDPWEGPVPEAQVVRVAAALHAMGCDELSLGDTIGVATPGQVGSLLRALHAA
                     GVEPGALAVHFHDTYGQALSNTVAALQHGVTVVDASAGGLGGCPYAQSATGNLATEDLV
                     WMLHGLGIDTGTDLGALVATSDWLAARLGRPSPSRTVRALSHQE"
ORIGIN
        1 gatgatcggc cagaagaagt cgttccagga ctgcacgaag gtcagcatcc cgagcaccgc
       61 catcgcgggc cgggccgccg ggaagaccac gtgccacagg acccgcaggc tgttggcgcc
      121 gtccacccgg gccgcctcga tgatctcggt gggcagcgcc tggagcaggt actgccgcat
      181 gaagaagacg ccgaaggcgg tgaccagggt cggcaggatg accgcctgga gctggtcgga
      241 ccaggagagc ttggccacca tcatgtacag cgggacgacg ctgagctggg gcggcaccat
      301 catcgtgccg atcaccagca gcagcagcgc gttcttgaac cggaaccgca gcttggcgaa
      361 ggcgaacccg gccagggtcg agaagagcac cgtgccgacc gagacggtgc cggccaccac
      421 cacggtgttc agcagggccg accccatgtt ggcgtcggtc caggcgatct ccaggttctt
      481 gaagaggttc ccgccgaacc agaagggcgg cggggtctcg gccagccgcg tgttgttccg
      541 cgaggccgcg atggccgtcc agaccagcgg gaagagcgag acgacggtga ccaggccgag
      601 cacggcgtac gtgatccggc cgccgtgcag ctggcgcccg gccccgttgc ggcgcgggcg
      661 ccgggaccgc ttgccgggcg ggtcggcggg ggcgccgggc gcggagtccg cccggacggg
      721 cggtggtgcg atgctcatgc tttcccctcg cctcggcgca gccaccgggt gaccgcgaga
      781 gagaccagcc cgatcacgat cagcagcagg aacatggccc aggcgatggc ggacgcccgg
      841 cccaggtgca ggttggtcca gccctgttcg tacaggtaca ggccgagggt ctggaactgg
      901 tggtcggagc cgccggtcgc cccgccgccg ccgttgaaga gcagcggctc gccgaagagc
      961 tggatggcgc cgatggtcga gacgaccacg gtgaacagga tggtcggccg cagcgagggc
     1021 agcgtcacgt gcaggaactg ctgccagcgc gaggcgccgt ccagcgccgc cgactcgtac
     1081 aggtcggagg ggatggactg catcgcggcc aggtagatca gcgcgttgta gccggtccac
     1141 cgccacacga cgatggagga gacggccagt tgcgaggtga aactgccgtt ctgccagtcg
     1201 atgtgctcga aaccggccag cgacaggaac cagttgatca tcccgtagtc gcgcccgaag
     1261 agcatgacga agaccagggt cgccgccgcc accgaggtgg cgtacggggt gagcgccgcc
     1321 acccggaaga acatcgagcc gcgcaggcgg tagttgagga ggtgggcgat gcccagcgcc
     1381 atcagcagct gcggcaccgt ggagaggatg ccgatggtga aggtgttctg gagcgcgttc
     1441 cagaagaact cgtcgtcgag caggcgcgtg tagttgcgca gcccgatcca ttccatgtcg
     1501 ttgggggccg tcagctccac ccggtggagc gaggcccacc cggtgtagag cagcgggaag
     1561 aggccgaagg ccgcgaagaa gaggaagaac ggcgcgatga acgcgtacgg actccacttc
     1621 acgtcccgcc ggtaccagcg ggagcgccgc tcgcgccgcc ggtcggccgc ttccctgccg
     1681 gggtcctggg gcggccccgc ggccaccgcc accccgctcg cgggggccgc cgcgccctcc
     1741 tccaccgagg agggcgcggc cgccgagaat tcactcgcca tcgcgggtca ctggtccaga
     1801 gcgttgtcga tcgccttgac cgcggccttc cagccctcct cggaggactt gcccttctgg
     1861 tcgacctgga gcatgcccac gtcggccagg ttctgcgcga tcaccaggtc cttcgggccg
     1921 aggatctgca ccggggcgcc cttggcggcc tcggcgaaga tcttgccgat cggcgcgtcg
     1981 tcgaagtact cgtggttggc gtcggcgatc tccggcaggt cgtaggcggc ctgcgcgctc
     2041 gggaaggagc cgcgctcggc gaagaacttg gcctgctgct cgggggcggt cagccacgcg
     2101 gcgagcttgg cggcctcctc cttgttcttg cccgcggagg gcaccgtcag gaaggcaccg
     2161 ccccagttgc cgggcttcgg cgcctgggcg acgtcccact tgtcggcgtt cttctcgccg
     2221 cccttgtcct ggatgtagcc gagcatccac gccgggcagg agaccgtggc gaaggtgccg
     2281 ttggagaagg ccttgttcca gccgtcggtg aactgctgga gcttggcggt cagcccctcg
     2341 gaggcgaact cggccgccag gtcccaggct tccttcaccg ccgggttcga cttgtagacg
     2401 acctcgccct tgtcgtcgta gtagcggttc gcgctgctgc cggtcaccgc cgccatcacg
     2461 ccgggggcgc cgtcgacgaa cttggcgccc ttgggggcgt tcttctggaa ctccttgccg
     2521 gcttccaggt acttgttcca gtcacccgcc cacaacttgc cgacctcctc acggtcggtc
     2581 ggcagaccgg ccttctcgaa gaggtccttg cggtagcaga tgccctgcgg gccgatgtcc
     2641 gtgccgagcg ccaccgtctt gccggcctgg gtggtgccct ggtcccactt ccacttcagg
     2701 aaggcgtcct tctcgacacc gggggccttg gagaggtcct ccagcttgtc gccctgggtc
     2761 tggacgatct cggcgatgtt gttgacctcg acggcctgga tgtcggcgag accgctgctg
     2821 gtgcccaggt gggtgaggag ctgcgggtag tagttctcgt tccgctcgat ggacgtctgc
     2881 ttgatgacga cgtccttgtt ctccttcatg tactggtcgt agagtccggc ctccttgagg
     2941 ccgaacgcac cgaagacccc gaccgtcagc gtggtcttcc ccttgtccga cccggcttcg
     3001 ttcccggcgg ccttgggctc gtcgtccgac gcgcagcccg cgagcaggct ggtccccagg
     3061 gcggcgacgg ccgccaggac caccgccttg cgggccgtac ggcttctcgt acgcatggtc
     3121 tcctcctgac gccggtccgg tcccggcccg tcaaccccct tgcgggcggc tgaagtcggc
     3181 tcctccgggt cgaaccaggg aatgtacggg tgttggagtg gcagctaggg tgggagcgct
     3241 cccacccgtg atgtcgtgaa gagtcgcggc tacgggcagg agtgtcaaga caccggacgc
     3301 cgccaggtcc ggtcggttat cgggctgtta cggtctcctc cgatcctggg gcacgacacg
     3361 ggcgcgtgcc cactactggg aggcaacgga tgacggctgg tcggagcaac gggcgcagcg
     3421 ggggccgccc caccctcgaa gaggtcgccg cccgcgccgg ggtcggccgc ggcacggtct
     3481 cccgcgtcat caacggctcc ccccgcgtca gcgagaccac ccgcgccgcc gtcgaggccg
     3541 ccgtcgcgga actgggttac gtcccgaaca ccgccgcccg cgcgctggcc gccaaccgca
     3601 ccgacgccat cgccctggtc gtccccgaac ccgagacccg cttcttcacc gagccgtact
     3661 tctccgacat cctcagcggc atcggcgccg ccctcgcccc gaccgacctc cagctcctcc
     3721 tcaccttcgc cgacggcgcc cgcgaacgcc gccgcctcgc ccagtacctg gccgcccacc
     3781 gcgtcgacgg cgtcctgctg gtctccgtcc acgccgacga cccgctgccc gacctcctct
     3841 cccagctgga gatccccgcc gtcatcagcg gccgccgcag cgaggacgag ccgctggcct
     3901 ccgtcgacac cgacaactac tccggcgccc gcgccgccgt cacccacctc ctggagcggg
     3961 gccgcaccac catcgccacc atcagcggcc gcctcgacgt ctacggcgcc cagcgccgcc
     4021 tcgacggcta ccgctccgcc ctcggcgacg ccggccgcca ccccgaggac agcctcgtcg
     4081 ccgccggcga cttcaccgag gagggcggcc gccaggccat gcgcctcctc ctgggccggc
     4141 atccggaact cgacgccgtc ttcgcctgct ccgacgtgat ggccgccggt gccctccagg
     4201 tgctgcgcga ggccggccgc cgcatccccg aggacgtggc cctggtcggc ttcgacgact
     4261 ccgccgtcgc ccggctgatg gaccctccgc tcacctccgt ccgccagccc accgccgcca
     4321 tgggccgcgc catgaccgag gcgctcctcg ccgagatcgc cgagggccgc cccgacagct
     4381 cccggctgcg cagaccccgg caggtcgtcc tggacacgga gttggtggtg cgggcctcca
     4441 cctgagcctg tcgcgccgcc gacaggtggt gcgcccgcgg cgcgcggccg agcctcccgc
     4501 ccccggcgca cccctcgccg taccatccct cgggtggaac tccccgacta cctgatcagg
     4561 cttcagcgcg cggccgacga cgagggacgc cggctcgaac acctcgacga ggacgagcgg
     4621 gacgcggcgc ggcgccgcta cttcaacgcc gcggccgagg tcgacgtggc cgtacgcgac
     4681 ttcgccgcca gcgccgggct cgaccggcac accgtggaga aggaactgcg ccagcaggcc
     4741 cgccagcctc ccacggactg agcgcggccc gctgtcgtac ccccggagta cggtcggctc
     4801 catgaacacc cgtacggaca ccgcgccccg ccccgccgcc gtggtcaacg ccgagatccg
     4861 cgccctgctc atgcgccgcg gcggcctggc ccccgccgag cgcgcggcgt acgagcggct
     4921 gctcgtggag tgggccgagg cggtccgcgc cgaggtggtc gtcgccgcct gatcctcccg
     4981 caaccgccgc gccctctccc tcgtcgtgat cgacaacggt cagacgagcg agaggaaccc
     5041 cgtgaccagg tggaagagac agcggaagag acagaagagc ggccgcggag ccctcccggc
     5101 agccctgatg gccgccgccc tgctggccac cggatgcggc gccgccgaca ccggcggccc
     5161 ggcgccccac cccggcctcg acgccttcca cgcccaggaa tgccccgaac tgaccgcgag
     5221 tgagaaggag aacggcaatc tcctcaccct cgcccacgac cagcccgagg tcggcgtctc
     5281 cctgcgcccc ggcggcgccc ccgccaccgt cctcgtcaag ctctgcaaca ccaccgaccg
     5341 gcccctgacc gacatcgccc tctccatcca actggagtgg tccgacgccg gggagcgcga
     5401 cccccggctg aaggtggagc accgggagac ccccgacggc cggtggcgct ccgccgaact
     5461 ggtcgtcgcc aacgactacc agcccctcag gggcgccgac gccgcccgcg acctggcccc
     5521 cggggcgacc cgggtcgtcg agtaccggtt cagcgcggcc gaggacgccc cgtccggcgc
     5581 acggccgctg atgatccagg ccgtccgggc cgacgagcag cgtggcggcg gcctggccgg
     5641 actgcgtctc agcgtcctgc cctcggactg acggccggcc accggtggcc cggcccgtcc
     5701 cctcaccacc catggccggc ttctccaccc caccgccacc gcgtgcacgg ccggggtacg
     5761 ggcgccgggc gagccgaccc ggcgctcctg cgcgcccgtg ccgaccgctg gcggcaggtg
     5821 tggcgccgtg cggtctgaga ggcggggcat gggtctcagc ccgcgtgttc caggacgtcg
     5881 tcggcgacct tcttctccag ggcggcccgg accagcgcgg cggcgaggac ggccgggccc
     5941 gcgtccccgg cgaggcgggc caggcgcttc gggtcctggg ggaggccgag ccgttcggcg
     6001 ccctggaggg ccttgccgtc gaagtggggc gcgtactcgg gccagaccgc ctgggcctcg
     6061 cggaggaaga tcccggcgcc cgcaggaccc atgcccggtg tctcctgcag gccctggacg
     6121 agggtctgct cgtcgccgtc ggccttctcg cggagctgcc gtaggtcccc ccggtgttcg
     6181 tcgaggagca gttcggcacc gtcgccgagc tgggtggcgg tccgctcgtc gtagcgccgg
     6241 tagccgccct cgcccagcgc gtccacccgc tcctgccagc tcgcgtcggc catggcgcgc
     6301 gggttgcgca tcccgtcctg gaacagggcg cgggcggcgg ccaccgcgac ggaggcccgg
     6361 atgcgggcgc tgagcaggga actgagaacg agcaactggt agagcggctg cggggtgtcc
     6421 ttgagggtga tccccgcctc gcgcgcgtag gtggtgccgt gccggtcgag gagcgtggcg
     6481 gcgacggcgg actgcgaagc actcacgtcc ggtctccctt cttaggaggc gtacgggtct
     6541 tcagggtgtg cctgcttccc actgtggcgc ggatcgggcg gggacgcgcg gggagcggcc
     6601 tgcggaaacg cctggagccc cgtcctgatc tctcaggacg gggctccagg ccacagggtg
     6661 agtgacggga cttgaacccg cggccacctg gaccacaacc aggtgctcta ccaactgagc
     6721 tacacccacc gcgtccggtc gtttccgacc ggccgagaaa aagtgtacag ggtccgaggg
     6781 ggtgctcgcg cacacctttt cccgggggcc gcgcggggcc ttattccgag gtcagcacgt
     6841 gctgggcggc gatcgccttc gcggtgtcgg agtcgggccc gggctgcggc acgaagatcg
     6901 cctcgcggta gtagcggagc tcggcgatgg actcgcggat gtcggcgagg gcgcggtggt
     6961 tgccgttctt gtcgggactg ttgaagtagg cccgcgggta ccaccggcgc gccagctcct
     7021 tcaccgagga gacgtccacg atgcggtagt ggaggtaccc ctccagcgcc gccatgtccc
     7081 gtgcgaggaa gttccggtcg gtgccgaccg agttcccgca cagcggagcc ttgccgggct
     7141 ccttgacgtg ctcacggacg tacgcgagaa cccgcgcctc cgcgtcggcc agcgtggtgc
     7201 cctccgccag ctcggcgagg agcccggagg cggtgtgcat cttgcgcacc acctcgggca
     7261 tggtctccag cgcctcgtcc ggcggacgga tcacgatgtc cacgccgtcg ccgagcacgt
     7321 tcagttccga gtcggtgacc agcgcggcca cctcgatgag tgcgtcgtcc gccagcgaga
     7381 gcccggtcat ctcgcagtcg atccacacca tgcggtcgtt catacggctc agcctaggcc
     7441 ctgtccgcga aaacccgtcc ggcccgtacg ggtccggcac acacccggaa gcgcgtgccg
     7501 gacccgcacg ggccggagca gtcctctctc agacgccgcc cagcggacgt tcccgctggc
     7561 ccgggagtgc cgcgcgcccc tggaggtagg cgtccggcgc cccccggccc gggtccccgt
     7621 ggtgggcgcc gaccccctgc ggcgtgcggc gcagctgcgg cgggagcggc ccgtcgaaga
     7681 cctgcaccgg ctgcgtgggc tgcaccggct cgggccgctg ctgctcctgc tgcggacggc
     7741 gggcgcggta ggcggcccgg tacgcggcgg gggaggagcc gagctggcgg cggaagtgcc
     7801 cgcgcagcgc gaccggcgac cggaagccgc aacgccctgc gacctcgtcc accgaatagt
     7861 cggaggtctc cagcaggcgc tgggcctgga ggacgcgctg ggtgatgagc cactggagcg
     7921 gggcgctgcc ggtcagcgag cggaagcgcc ggtcgaaggt ccggcggctc atgtacgcgc
     7981 gcgcggccag cgtctccacg tcgaactgct cgtggaggtg ctccagcgcc caggcgacga
     8041 cctcggccag cgggtcggcg ccgatctcct ccggtaaaga cctgtcgagg tagcgctcct
     8101 gcccgccggc ccggcgcggc ggcacgacca ggcggcgcgc cagggcgccc gcggcctcgc
     8161 tgccgtgatc ggtccggacg acgtgcaggc agaggtcgat cccggcggcg gtgcccgccg
     8221 aggtgagcac gtccccgtcg tcgacgaaga gctcccgcgg gtcgacgtgg accgaggggt
     8281 agcgcttggc cagcgtcggc gcgtacatcc agtgcgtggt ggccggcctg ccgtcgagca
     8341 gcccggcggc ggccagtacg aacgcgccgg tgcacagacc gacgatgcgc gcgccctcct
     8401 cgtgcgcccg gcgcagcgcg tccagcgcgg cggcgggcgg gggtgaggtg atggaccgcc
     8461 aggcgggcac caccaccgtc cctgcccggg cgagggcctc caggccctga ggcgccgtca
     8521 gttccagtcc gccggtggtc cgcagcggtc cgtcctcgcc ggcgcagacc agcagccggt
     8581 agcgcggcac gcccgcgtcc tggcggtcga tgccgaagac ggagagcggg atggaactct
     8641 cgaagatggg accgccgctg aagaggagaa ccgcgacgat ctccttgcgg cgccgcccgg
     8701 agagtttgcg gcccgcgagg tccgccgtga cggtggagtc gtggctcatg tggctaagcc
     8761 cccctcggtg gccgtgtcac tccagtcctg tcggatctgt cgctcctgca cgtttcccct
     8821 cggtcctgcg cgtgtccccc gccataagac agtcatgatc gaatctactg tgtcccgtgg
     8881 tgccaccgtg accagttgag cagacgccgg aatgtcgaca aggcaacgtg gcgtgaagca
     8941 ttcgatcacg aagcgtcgca ctccagggct cgactgggaa gtgcgtctgc ggcgggtggc
     9001 cggtccccgt agggtgcgaa cgcctcgcac ggtcctgtcc tcgcaggtcg tgccgggggt
     9061 gacgggggtc cacccaccct ggtgcaacgg ttcgtcaact tggctgaaaa catacgggcg
     9121 cgtgcgtgcg aaccggtcag ctctccggtg tacggaaagt gcgccccctg accgcccccg
     9181 tgcgcccctc tcccctccta cctgggaacg tctcccgccg cgcaccgggc gcccgccgcg
     9241 ccccgctccg cccggcgcaa cagcagccgg cagatcccgg tcaccgcggt cagcaccggc
     9301 gccacccaca tcaccccgcc cgccgccgcc ccgtagacca ccaggaccac cggggcgagg
     9361 acgcagccga aggcggccca gcgcgccgcg gtgctcacgg gggccggtcc ggcgccccgc
     9421 gccgccgtgg aggccgcggg tgcgctggcc gcgccgggcg cggtgcgggc cccggggagg
     9481 ccgcgcgggg ccctggcgcc cgcacaggcg gctccgggcg cccgcgagcc gcgttccggc
     9541 gcccgtgcgg gcgtggggcg ggggaggagg gtggcggggt ccgggccgga gacgtggggg
     9601 acgggcacga ggggctccca gggtgggcgg gtacgccggt tcaacgctcc gcccgcgccc
     9661 gggtcactgc ggggtggcgc gggctgggcc gacccgggga ccccgtgtcc cccgggcggc
     9721 ggggccgtcc ggccgttgcg atcggggcgc ggctccggca tgctccctcc agcgcgccgc
     9781 ccggcggtgg cgtccgggcg ggcctcacca ggccggttcg ggaccctccg ggagctttcg
     9841 ccgggcggtg cgcgccggtc cgtgagaacg gcgcatgggg gagccctctt ctgggtacgg
     9901 gcggtgcaag gtccgaacgc gggagaagtg gcgccgtacc cttggggcga gtggttggga
     9961 agatgcttcc cggacacagc gggccggtcc caccggccgg tcgtcgcccc tccgggcgcc
    10021 gtcggcaccg ctgctcgacc tccggacccg gggttccccc cggagccgtg ctcattccgt
    10081 cagccgtccc cttcccacga gtcccccaag gacctctccc gccgagacac cgatggccgg
    10141 tcacgaatcc tttgaatcag cggaccgcaa gcggcaggtg gccgatccct cggcccagcc
    10201 cctggcggcg gaagaaacac gtcagccctg cgatccggcc ttccggcacg gcgtcgtcgt
    10261 gggcttcgac ggctcgacct ccagcgagcg cgccctcgcc tacgcgatcg gcatggcccg
    10321 ccgctcgggc tcgggcctga tcatcgtcca cgtggccaac cggctgccca ccacggtgtg
    10381 ggccggctgc gagccacccg tcttcgtcga cgtgcccgac caccgcaccg aggtgctggg
    10441 gctggagctg gcctgcgccg agtacctggg ggacgtctcc tggattctcg tcgagcgcgg
    10501 cggcgacatc tgccacgagc tggaggaggt cggcaccgag tacgaggccg acgccatcgt
    10561 ggtcggctcc agccagggcg tcgtggggcg gctcttcggc tcggtcgccg ggcggctggc
    10621 ccggcgggcg cgcagaccgg tggtcgtcat cccctgagcg gggcgggccc aggggacgac
    10681 gaggggaccg gctactcgac ggtgacggac ttcgccaggt tgcgcggctt gtcgatgtcg
    10741 cggccgagct tcagcgcggt gtggtacgcc agcagctgga gcgggatgcc catgaggatc
    10801 gggtcgagct cgtcctcgtt cttcggcacg acgatggtgt ggtcggcctt ctcctgctcg
    10861 cggtgggcga cggcgaggat cttgccctca cgggccttga tctcctccag cgcggcccgg
    10921 ttcttctcca gcaggtcgtc gtcggggacg atcgccacgg tcggcatggc cggctcgatg
    10981 agggccagcg ggccgtgctt cagctcggag gccgggtacg cctcggcgtg gatgtacgag
    11041 acctccttga gcttcagcga ggcctcacgg gccaccggat agccccgcac gcggccgatg
    11101 aagagcatcg agcgggcctc ggtgaactcc tcggccagct tctcgatctc gtcctcgcgg
    11161 gagaggatgt cggcgatctg ctcgggcagc ttgcgcaggc ccgcgatgat ccgcttgccg
    11221 tcggccaccg acaggtcacg ggtgcggccc aggtgcagcg cgagcaggcc gaaggcgacc
    11281 acggtgttgg tgaagcactt ggtggagacc acgcacacct cgggcccggc gtgcacgtac
    11341 agcccgccgt cggcctcgcg ggcgatggcc gagccgacca cgttgaccac gccgaggacg
    11401 cgggcgccct tgcgcttcag ctcctgcacg gcggcgagca cgtcgtaggt ctcgccggac
    11461 tgggagacgg cgatgtagag cgtgtccggg tcgaccaccg ggttgcggta gcggaactcg
    11521 gaggccggtt cggcgtcggc ggggatgcgg gccagctcct cgatgagctg ggcgccgatc
    11581 tggccggcgt ggtacgaggt gccgcagccc aggatcttga tccggcggac cccgcgcgcc
    11641 tcacgggcgt cgaggttgag gccgccgagg tgcacggtgg agaaccggtc gtcgatccgg
    11701 ccgcgcagca cccggtcgac cgcctcggcc tgctcgaaga tctccttgtg catgtacgtg
    11761 tcgtggccgc ccatgtccca ggactcggcc tcgtactcca ccgtggtcgg cgtggcggag
    11821 gtgcgcgagc cctcggtggt gtaggtgcgg aagtcgtcgg ccttcagggt cgccatctcg
    11881 ccgtcgtcca gggtgacgac ctggcgggtg tgggagacca gggcggcgac gtcggaggcg
    11941 acgaacatct ccttctcgcc gatgccgagg acgaccgggg agccgttgcg ggcgacgacg
    12001 atccggtccg ggaagtcggc gtgcagcacg gcgacgccgt aggtgccctc gatctggccg
    12061 acggcctcgc ggaccttgcc ctccagggtg tcggcctcgg agcggccgat gaggtgggcg
    12121 aggacctcgg tgtcggtctc ggagaggaag accacgccgt cggcggtgag ccgggcgcgc
    12181 aggtcggagg cgttgtcgaa gatgccgttg tggacgacgg cgaccttgga gtcggcgtcc
    12241 aggtgcgggt gggcgttctc gtcgttcggg gcgccgtggg tggcccagcg ggtgtgcgcg
    12301 atgccgacgc tgcccttgaa gcgggccggg accctggcct ccaggtcgcg gacgcggccc
    12361 ttggccttga ccgacttcag cccggtcgac ttggagcccg acttgccgtg gatggcgatg
    12421 ccggccgagt cgtaaccccg gtactccagg cgttggaggc cctccagcag cagcggcgcc
    12481 acgtcgtcgc gacggccgat gtatcccacg attccgcaca taggtgaaac ccctcctgga
    12541 cgtgttccgg cgggccggtg ggcccgcccg ggtgctcggc gctcccggca tgagggtgcc
    12601 gggcggcctg gtcagccgta gacgatgcgc cgcagctggc gcagggagag tgccgggggc
    12661 gccacggccc tgcgcggcag ctcctcggcg atccgctcga agatctccgt gttgcccagg
    12721 ccctgggcct ggagttcgcg gtgacggcgg cgcacgcact cctcggtcgt ctcgtcgaag
    12781 tacgccagga cgtccatgac cacccggccg gcctcgccgc ggctcagcgg cgtggtgcgg
    12841 accaggtggt cgaccaggtc gtcgtggttc gtacggcgtt cgagcacgga tcgatactgg
    12901 gtcgcgcgga cggctttcgc aacattcctg cccgatatcg ggcacggggg agcgggaagt
    12961 ggggcggaat gggggattcc agcggcttcg cgtgctccgg ccgctctcag agccggcgca
    13021 gcaccgcctg cttggcgagg ctgaactcct cgtccgtgag caccccgtcc cggtgcagct
    13081 cgcccagctc ccgcagccgg cgcagcagcg cgtccgggtc gtcggcggcg ccggcctgcg
    13141 gagccggggc ggacggcagc gggagctggg cgggcacctc ggccttgtcg agcgcgccgg
    13201 gggtgcgctc cggctcgccc cgggccgcga gcgccaccag gaccgccgcc gcgaccagca
    13261 cggccgtgtg ctccttcttc gacaggcccc acaggtccag ggcgtgcggg tcgtgctcgg
    13321 gcgccacggt cttgccgccg ccggagcggg tgaggaagcg gaggtgcccg ttctccaggc
    13381 cctgcgcggg cacccaggag acgccggtga ggtcggcgag ggccagcgtg gtcgggccgg
    13441 cggaggtctt cgtctccttg cccttccagt tccaggtcag ccgtacctca cgcccgtcga
    13501 aggcggccgt cccgtccccg ccgccgcccg acaccggcag cgccggaccg ggcagcagga
    13561 accgctcgac cgggccctcg gggatctgct ccagcagcag cgcctggcgt acctcggcca
    13621 cgacgtactc ggccaggtcc tcccggcccg actcgaccac cagccggtac gggtcggcgc
    13681 cctcgggcag ccgtccctcg gcggcccgca ccaccgggca ggccccgtcc cgcagccgca
    13741 gccggagccg cccgcccttg cggtcccgct cgaaggtgat cccggcgacc gccgtcagcg
    13801 gcaccaccac ctcgccgagc acctgccgca ccggatgggc cttggcgccc ggcacgatcc
    13861 gtatgcgcct gtcctcgtag ctccagctgc cgtcccgctg cgtgatctcc gccatgcggg
    13921 gattctttca gtacgaaggg gacggcgggc gccgcccggg tccgtacccg ggtggcgccc
    13981 gccgcggcgt ggggcgggac tcagcggccc gcgagggggt tgaccaggtc gccgacgagc
    14041 tggagggcgc ccgaggggtc ggccaggtcg accatctgct ggttgtcgcg cagctggagc
    14101 cggttgaggc aggagagcgc gaaggtgggc gcgaacatgt cgtactgggc gaacctgtcg
    14161 gccagctgcg gcatggactc ctggtacgcg cggacgctct ccgccgccgt gcgccagaag
    14221 gtgtcctcgt cgaggacgcc ctcgccggcc agggtggcgt tgaggaagcg caggtagcag
    14281 tcgaagacgt cggtgaagat cgagaggatc ttcatctcct ccggcacctc ggccttgatg
    14341 cgctcgaccg cgggcggcag gaccgcgtcc gggtccatga cgcagatctc ctcggcgatg
    14401 tccttgaaga tcacccggtc gaccgcgccg tcctcgatga cgaggatgac gttctcgccg
    14461 tgcggcatgt acaccaggtc gtactggtag aaggagtgca gcaccggcac gaggtacgcg
    14521 tccaggtagc ggcgcagcca cacctcgggg gccagccccg actcggcgat cagcgcgccc
    14581 gccagggagg cgccgtcggc gtcggtgtgg agcagcgagg ccatggtggc cagccgctgc
    14641 ccctcgccga gctgcggcac cgggctctcg cgccagagcg cggccagcat cttgcggtac
    14701 ggcgagtacc ggtcggtggc ccgctcgtac tggcggtggt ggtagccgat ggcggcgcgc
    14761 tcgcggatga tcgagaagcg cgcggcccgg aagacctcgt caccggcgat gagctgggcc
    14821 agccagtcgt tgatcgccgg ggtggcctcc atgtaggcgg ccgacaggcc ccgcatgaag
    14881 cccatgttca gcaccgacat ggcggtcttc acgtagtgct tgtcggggtg gctggtgttg
    14941 aagaaggtcc ggatcgactg ctgcgcgagg tacgcgtcgt cgccctcgcc gagcaggacc
    15001 aggcgctgct gggcgacctc ggcggcgaag gagacggaga gcttgttcca ccactgccag
    15061 gggtggaccg gcagcaggtg gtagtcggcc aggtcgagcc cctggccctc cagggtggcg
    15121 gcgaaccggg ccagcgtcgc cgggtccagc tcgcccttga ccagcgtgtc gtagtcgagc
    15181 ccggcgccgc tggtgaaggt ggagcggtcg cggcgggcgg ccagccagag cagccggacg
    15241 ggggaggcgg tctcgggggc gtactggtgg tactcgcgga cgtcgaagcc gatccgcccg
    15301 ttgttggcga cgaagcaggg gtggccctcg gtcattcccg tctcgatggc ctggaagccg
    15361 gcgcgggcca gttcggcggc gctcgggcgg gcctgggcca gcttccaggc ggcgccggag
    15421 agggtggagg agatctcctc caggtagacc gggaggatgg cgtcgccgat gcccagcgcg
    15481 gtccgggtgt cgaggatgaa gtcgagtgcg tccagcggga gttcggtgcc gccctcgccg
    15541 tgccgggtga tcgagtcggc ggcgatgtcc cagtggtcca ggctcagcag tttcgccgcg
    15601 aagcggtact cggtcacgcc gtcgtcggtc accacgcggt gggcggtgcg gccctcggcg
    15661 tcgggctcgg cgccggggag cggctcgggc gtcagcagcc gctcgtggga gaactcggcg
    15721 aggcccttgc ggaccaggtg gcgcccggcg gcggcccaca gctccggcgt gaggtgcgcg
    15781 gtgggcgcgg cgagctgctc ggtgggggtg gtgtcactca tcggggagcc tgctccttcg
    15841 tgtcgtcccc cgccggtacg gtcgccgccg ctttcttcgc cgcctcgaag gcgtcccggg
    15901 tgcagacgct caggtacgcc tccttctcgg gcttggcgat cttccgggcg atttcgaagc
    15961 cgacggcctc gttgagcgcg tggacggccg cgttgcgcac gtcgggctcg accacgacgc
    16021 ggacggtgtc cgggtcggcg aagaggtact ccatgaccgc gaagatcacc gcgcgggtga
    16081 agccgtgcag cggcgtgtcg gtcggcgcgc agaggaagtg catgccgacg tcgccgggct
    16141 cggggtcgta gaggccgacc agctccacgt gggcggggtc gtaccgctcc atgaggaagg
    16201 ccggggagtc ctcgtacagg ccgatgaagg cgtcgtggtg cgggtgggcc gcgatcgagg
    16261 cgtactcgcc gcggacctcg tcgacgctga gtccctgcat cagccagaag gccgatttcg
    16321 ggtgggtgac ccagccgtgg accaggccgg cgtcggcgtc caggtcgagg gggcgtatcg
    16381 cgagccggtc ggggcggact ttcgcggtgc ggggggtggt catacggaga actcctggaa
    16441 ggcgatcgac ttctccaccg cgtagggggc ggtgcccagc agctcgcgca ggatgacgga
    16501 gttgcggtag gcgcccatgc ccaggtcggg ggaggtgagg gcgtgggtgt ggacgccggc
    16561 gttctgcacg aagatgccgc gcccggtggt gtcgatgctg tagttgcggg cgatgtcgaa
    16621 ccggccgcgc ccgtcccagc ggatgcggtc gcggacaggc tgcaggaagt cggggacgcg
    16681 gtactggtag ccggtggcca gcaccaggcc ctcgctgctc agcacggagt ccttgccctg
    16741 ctcctcctgg cggagcccga gcgtgtacgt gccctcggac tcgtcccaag cagcggtctg
    16801 gagcgcggtg ttggtgagca gccgggtggg gacggggccg cgcacgctct tctcgtagag
    16861 caggtcgaag atggcgttga tgagttcgcc gtcgatgccc ttgaagaggt tcttctgctt
    16921 ctgctccagg ccgtaccggg tgtcctcggg cagcgcgtgg aagtagtcga tgtactccgg
    16981 ggaggtcatc tcgagcgtga gcttggtgta ctccagcggg aagaaccggg gcgagcgggt
    17041 gacccagttc agctggtagc cgtggacgtc gatctcggcc aggagatcgt ggtagatctc
    17101 cgccgcgctc tggccgctgc cgaccagggt gatcgacttc ttggcctgga gggccgcttt
    17161 gtgctccagg tagcgggagt tgtgcagcag gtcgccgccg aggccctggc agggctcggg
    17221 gatgtgcggc ggggtgccgg tgccgagcgc caggtggcgg gcgcggtagg tgtcgccctg
    17281 gtcggtggtg acggtgtaga gcgcgttctc ctcgtcgtac gtcacctcgg tgacggtggt
    17341 ggagaagcgg accgagccga ggcgggcggc ggcccagcgg cagtagtcgt tgtactccgt
    17401 gcgcagcggg tagaagttct cccggatgta gaaggagtac agccgcccgg actccttcag
    17461 gtagttgagg aacgagtacg gcgaggtcgg gtcggccagg gtgaccaggt ccgacatgaa
    17521 cggcgtctgg aggtgtgcgc cgtccaggaa catgccggag tgccagtcga agtccggctt
    17581 cgtctccagg aagagcgcgt cgatctcgtc cagcggctcg gcgaggcagg ccagcccgag
    17641 gttgaacggg ccgaggccga tgccgagcag gtcgagcggc tcggcggagt cggaggcggt
    17701 gcgggacgat cgctcaagag gcgtggacaa gggactctcc caggtactgc tcggcgtggc
    17761 cggctatgag gtcgaggacg gcggcgatgt cggacgcctt cgtctcgggg ttgagaaggg
    17821 tgaacttgag gtagtgccgc ccgtccacct tggtgcccgc cacgacggcg tcaccggagg
    17881 cgaacagggc cttgcgggcg tacaggttgg cgcggtcgat ctgcgccggg tcggtgggct
    17941 gcccgggcag gtagcggaag accagggtgg agagcgaggg ctccacgacc acgtcgaagc
    18001 gcgggtcggc gacgagcagc ttccagccct cgccggcgag gtcgcagacc tcgtcgaaga
    18061 gctggccgac gccgtcggcg cccatcacgc gcagcgtcat ccacagtttc agggcgtcga
    18121 accggcgggt ggtctggagc gacttgtcca cctggttggg gatgcgctcc tcggcggccc
    18181 ggcgcgggtt gaggtagtcc gcgtggtacg tggcatgccg cagcgtggcg ccgtcgcgga
    18241 ccagcagagc ggaggaactc acgggctgga agaaggactt gtggtaatcg acggtgaccg
    18301 agtcggcgtg ctcgatgccg gtgagcagcg cgcgccgggt gggcgagacg agcagaccgc
    18361 agccgtaggc ggcgtcgacg tgcatccagg tgttgtgccg ggcgcacagc tcggcgatct
    18421 cgggcagcgg gtcgatggag ccgaagtcgg tggtgccggc ggtgccgacg accgccatcg
    18481 ggaccaggcc ctcggcctcg cagcggcgca gctcggcggc gagcacctcg atccgcatgc
    18541 ggcgctcgcg gtcggtgggg atggtcacca ccgcgtccgg gccgagaccg agcagcgtcg
    18601 ccgacttgcg gacgctgaag tggctgacgt cggaggtgaa gacgcgcagc tgggtggggt
    18661 gcgcggcctt ggcctcctcg cgggcgagca gcatcgcctg gaggttggac tgcgagccgc
    18721 cgctggtgaa gacgccgtcg gcgcccccgc cgaggccgat ccggcccgcc gtccagtcga
    18781 tgaggcgccg ctcgatgagg gtgccgcccg ccgactggtc ccaggtgtcc aaggaggagt
    18841 tgaccgccga gaggaccgct tcgccgagca ccgccgggat gacgaccggg cagttgaggt
    18901 gggccaggta gcgcgggtgg tggaagtaga cggcgtcacg gaggtacacg tcggtcagct
    18961 cgtccagcgc cgcggcggtg tcgccgagcg ggcggtcgag gtcgacggcg tcgaccacgg
    19021 gggcgagcgc tgccggggtg acgccggtga acgggctggt ggcacctgtc agcgatgcgg
    19081 ccacgcgctc gacaccttcg gtgacggagc ggcggtacgc ctccacgttc aggtcgttca
    19141 gcaggtgaga cctgggcgcg aggagactca tgagcggtcc tcccggtgag gggacttgtg
    19201 atgctcctgg gggtgagcac cacagggggg cgatgaactt aggtgagcct aacctaatgt
    19261 cgacctgagg aagtccacag ggggcgattc ccgtcaactg tggccggatg tgcagcgttt
    19321 ggccgtgaag cgtccgccgg agggtggggt tcgcggtcga agtgtcctcc ttcgcgcctc
    19381 ttgttcgagt ggtcggggtt tgcggtggac gtgtggggaa cgtgtgcata cctgacgccc
    19441 cgtcagccgg acggaccgca aagagccccg cccacccctc ttcggggtgc gcggggccgg
    19501 ttccctcagg ccgtacgccg tttgccggtc gtcagcgact ccgcgcgcag ctgctcctcg
    19561 ctcgcgccct cgcgccagta cccgacgaag gtcaccgccc gccggtcgaa gccgcgctcg
    19621 cccaccaggt ggcggcggag cgtccgcatc cggcccgcct ccccggcgat ccacgcgtac
    19681 ggctcacccg cgggcagctc cgccgcccgg accgcctcgg ccgccgaggg ggcgccctcg
    19741 tccgcgacca gccaggtgat ctcggcgtcg gccgcggtgg ccagctcgcg ccggtcctcg
    19801 gcgtgcggca cctcgatcca cagccgcacc gggaaaccgg ccggcagcca ctccaggatc
    19861 gcctcggtgg ccggcagtga ggtcaggtcc gcccacatca gcgcccacgc ggccgacccc
    19921 gggggccgga accgcaccga cacgttctcc gtcaccgccg ggcccagcac cacgatccgg
    19981 tccccgggca gcgcccgcgc cgcccaccgg caggccgggc cggtgtcgcc gtgcagcgcg
    20041 aagtcgacgt cgaactcggt cgtcccgtcg tcggcccgcc gctgcgcccg cacggtgtac
    20101 gagcgcatca ccgcccgctc ctcctcgggc atcgcccggt acgccgccca ccagtcctcg
    20161 cccgcctcga tgggcacccg cggcacgcgc tgccccgggt gcggcaggaa gagcgagcaa
    20221 ctctggtccc ggccgcccga ctcgaagagc gccagctcct cgccgccgaa ggtgagccgc
    20281 accagcgagg gcgacaggcg tcggctgccg cgcacctcca cgtcgaagaa gcggaacggc
    20341 gtacggacgg gagcggtggg cgtggtggtc atgagacggg ccttccctcg gcgtcgacat
    20401 ggcgctgagg taagcctaac ctcaccattg cggcgtgggg agaggcaggg ggcaccctcg
    20461 tgccggcggc tcagcgcggc agccccgcct ccgcgatggc cagtacctcg gtgatggcct
    20521 cgcccggggt gccggtgccc ggggcggtgt tccaggccca ctcctcgacg gccacgcgca
    20581 gggcggtgtt gagcagggcg gcctggacgc ggggttcgag ggcgtccggg gagaggccgg
    20641 tgcgggcggc gaagacgcgg gcgaggaccg gttcggccgc gtggtggacc tggagccaga
    20701 ccgcgcgcag ccccggctcg gtgcggacca ggcggaccag gtcgcgcagc gcctgctcgt
    20761 cctcggcgag ggcggtggcc gaacggccgg gcgggtgcgc gctgatgccg tcggtcaggg
    20821 tgcgctcgcg cggccaggag gtgagccgtt cggcggccgc gtccagggcc gtggtcagca
    20881 gcgggccgac gcactcctcc ttggaggagc agtaccgcca cagggtgcgc ggggagatcc
    20941 cggccgccgc cgcgatctcg tcggccgtgg tggccgcgac gccctgggcc gcgaagaggc
    21001 ggaccgcctc gcgggcgatc tccagccgcg tcgccgcctt gcgccgctcg gtcagcggcg
    21061 gccggccgac ccgccgcccg tccttctcct ccgccacacc ctcaccccgt cccgcgtccc
    21121 ggccgtcacc tgcggtgatc ctacgtccgc ggcctgatcg cacgcctttg tggcgcgctc
    21181 tgcctttatg gcacccgccg ccataaagga ggtaccgtcg ctcgtgcaca ccccctgaac
    21241 ccaggagcac gccatgagca gcaccaccgg cctcgcgggc cgcgccgtcg tcgtcaccgg
    21301 agccgggtcc ggcataggca gggcggcggc cctgcgcttc gccgccgagg gcgccaaggt
    21361 cctcctcgcc gacctgaacg gcgaggccgc cgaggccgcc gcccgggaga tcgccgaggc
    21421 gggcggcacc gccgtcaccg tcaccggcga cctcagcgac caggccgtcg tcgaccaggt
    21481 cgtcgccacc gccgtcgagc ggttcggctc cctcgacgtc ctcgtcaaca acgccgggat
    21541 catggaccgc atgtcggccg ccggggagac cgaggacgcc gagtgggagc gggtcgtccg
    21601 ggtcaacctc accgccccgt tcctgctgac ccgcgccgca ctgccgcacc tgctcgccac
    21661 cggcaagggc gccatcgtct tcaccgcctc cgaggcgtcc ctgcgcggca gcgccgccgg
    21721 cgccgcgtac accgcctcca agcacggcgt cgccggactc accaagtccg tcgccgtcat
    21781 gtaccgcgag aagggcctgc gcgccaacgc catcgcgccc ggcggcaccg ccaccaacat
    21841 ccaggtcgac gccgacggcg aggcccacgg ccccgccgtc ctcggctcct acgtgcgcaa
    21901 cgtcggcagc cccgcccagg ccgaggagca ggccgcggcc atcgtcttcc tcgcctccga
    21961 cgccgccagc aacatcaacg gggtgatcct cccggtcgac ggcgggtggg ccgccgtctg
    22021 agcctccggc ccgccgtacg gtcgtcgtgg tgaagggcgc ggcccccgct ccggggccgc
    22081 gccgcagcga ccgcgcgagg agccgccgtg aaccaggacg aggaacagat ccgccgcctc
    22141 atcgaggagt gggcgtccgc cgtccaccga ggcgacctcg ccaccgtcgt ccgcgaccac
    22201 gccgacgacc tcgtgatgta cgacgtgccg cccccgtacg aggggctgcg cggcctcgac
    22261 gcctaccgcg ccgtctggcc cggcttcttc gcctggcagg catccggcgc cgagttcacc
    22321 ctcgacaccc tcgacgtcac ggccggccag gacgtcgcgt acgcccacgc cctcctgcgc
    22381 tgcggcaccc ccgaggaact ggccgaacac cccgcgctgc gcctgcggct gacgctgggg
    22441 ctgcgcaagg aaaacggccg gtgggtggtc gcccacgagc atcactcgtt cccggacctc
    22501 tcctcgccgc ccgagtcgtc ctcgtcggca ggccgagcct cgtgagcccg gcgaggtagc
    22561 ggcggaccgg agctgggtcc aggcagcgcc ggctcccgcg gcgccccgcc cgccgccgcg
    22621 tcggccgtcg gcgcgtgggc gcacgtgcgg cggtgatcgg tgcgtgggac ggagccgtac
    22681 caggacatgt gcctcgtcga cggatggacg cacgatctgg ccgaggtcgc caggccgccc
    22741 gcgcctgacc ctcgtcggcc cctgtccggt cgcgaacgac gacgggacgt acggggtcgg
    22801 cacgggcatg ctcaccccgg acctcggccc gttcgcgacg ggggagtgac ggtccggggc
    22861 gggcccggag cggctcaggc ggacccgccg ggctcgtcgg gcaccggcgg cgccgtcagt
    22921 ccggcgagga cgaaggcggt caccgtcgcc gtggccggga aggaggcgtt ctcggcgggg
    22981 cccttggccg tcgggcgccc gtaggtctcc atcaccaggg tgaacgcgag ggcgcaccgc
    23041 tcgctgacct ctctcgggga cagttccggc agggcgcggc cgacgcgtac ctcgaagggg
    23101 gccggggtga gggcggtcgg gacgtggggg agctggcccg aggggagggc cgtccgggcg
    23161 aggagatggc acaggacccg gccgtcgcgt gtcgcgacca ggtcggcgaa gggctcgacc
    23221 agcccctcca ccaggcgccg gacctcctgg agcccggtcg cgcggccctc ggaggaggcg
    23281 gcccagcggg agttccagac gggtcccagc tcctgttcca gcagggccga caccagaccc
    23341 tcgcgggagc cgaagtggta gtggaccgcg cccgggttga gcccggcggc ggcgttgacg
    23401 gcacgcaggg agacctggtc ggcccccttc tccaggaaaa gctgcttggc cgccgccagg
    23461 aggcgctgcc gggtcgaggc gtccgctgtc acgccgcaca ttccatcaca gccgggagca
    23521 cgcgggactc ccgttcaatc agtgattgga ttatgttggg aaagcggagg ccgggtcgcg
    23581 cgacacggcc cctcgcaccg aacagcggca aggcaaggag cacggccatg ggtacgtacg
    23641 cggtcacggg aagcgcctcg ggcatgggag ccgccagcgc ggcccggctg cgggaggccg
    23701 gacaccgggt cgtcggcgtc gacctgcggg acgccgacgt caccgccgac ctcggcaccg
    23761 ccggcggacg ccgccacgcc gccgacgaga tcctgcgact ctgcgacggg gctctggacg
    23821 gcgtcgccgc cgtggcaggc gtcggcccga acctccccga cgcggccgcc gtcgcctcga
    23881 tcaactactt cggccccgtc gccctcctcg acgccctgcg ccccgccctg gagcgaaacg
    23941 gcggcggccg cgccgtcgtc atcggctcca actcggccac caccgtgccg atgatcgacg
    24001 accacctcgt cggcctgctc ctcgccggcg acgaggaggc cgcccgtacc cacgcggccg
    24061 gcgcccagcg ctccctcccc gccgaactgg ccgccaccag ccccagcatc agcgcctacg
    24121 ccacctcgaa gttcgccctc gcccgctggg tcaggcggac cgccgtcacc cccgagtggg
    24181 cccggcgcgg catcaccctc aacaccctcg cccccggcgc cgtcgtcacc ccgctgatga
    24241 ccggctccac catgtccgag gacgacctcg acccggatgc cttccccacc ccgatgccgc
    24301 gcgggatctt cggccgcccc gccgacatcg ccttctgggt cgcccagttc ctcagcccag
    24361 aggccgggtt caccaccggg gcgaccctca ccgtcgacgg cggcacggac gccgccctgc
    24421 gccccgacgc ccagcccacg gccatgcccc gctgacccga accgcacccg ggcccactgc
    24481 ccgccgtacc gaaggcagga cagcaccatg cagccgcgca ccaccccctc cgccttcccg
    24541 cccgcttccc cgcccacctc ccctccggcc ctcttcgaac ccgcccgcct cggccctctc
    24601 accctgcgca accgcttcat caaggcggcc acgttcgagg ggatgacccc gggggcgctg
    24661 gtcagcgacg agctgatcga cttccaccgc cgccacgccg ccggcggtgt cgccctcacg
    24721 accgtcgcct actgcgccgt cgcccccgac ggccgcaccg aacgcgacca gatctggatg
    24781 cgccccgagg ccctgcccgg cctgcgccgc ctcaccgacg ccgtacacgc cgagggcgcg
    24841 gccgcctccg cccagatcgg ccacgccgga ccggtcgccg acggacgctc caacggcctg
    24901 cccgccgtct cctcctcgcc gaacttcaac ccgcggagcc tcggggtcat ccgccaggcg
    24961 agccgccagg acatcgcccg catcacccgc ggccacgccg aggccgccag gctcgccgtc
    25021 gaggcgggct tcgacgccgt cgagatccac ctcggccaca actacttcgc cagctccttc
    25081 ctcagcccga agctcaacaa gcgcaaggac gagtacggcg gctcgctcgc ccaccgtgcc
    25141 cgggtggccc gggacgccgc ccgcgccgtc cgggaggccg tcggcgaccg gatcgcgatc
    25201 ctcgccaagc tcaacatgga cgacggcgtc cccggcggcc tctggctcga cgagagcctc
    25261 caggtggccc agtggctcca ggcggacggc agcgtcgacg ccctcgaact caccgcgggc
    25321 agctcgctgc tcaacccgat gtacctcttc cgcggcgacg ccccggtacg cgagttcgcc
    25381 gccgccatgc gcaacccgct ggtcaagcag ggcgtcaagg ccgtcggcaa gcacttcatc
    25441 cgcgcgtacc cctaccagga ggcgtacctc ctcgacagcg cccgccagtt ccgcgccgcc
    25501 gtggacctgc cgctggtgct cctcggcgga gtcagccggc gggagaccgc cgaacaggcc
    25561 atggccgagg gcttcccgtt cgtcgccatg gcccgcgccc tcctccgcga acccgacctg
    25621 atccgccgca tgcgggacga cgccaccacc cgctccctgt gcatccactg caacaagtgc
    25681 atgccgacca tcttcagcgg cacccactgc cccctcgcca ccccgtcggc cccctgaccc
    25741 ggccgccccg ccgggccccg gtggcgagga cgttcgtacg ctggccgctg tccgtcctcg
    25801 ccaccgcacc gcacaggagg ccccatggac cagggaggcc aggccacccc cgccgtggac
    25861 cgtacggtca cctaccagga ggacccgccc cgcacctgga cccggatctg cctcgccgcc
    25921 tacgccctct gggccgtcta ccaggcgttc cagctcctcc cggacgagct caccgcctgg
    25981 ctggtggtct gcgccatgtc cctgctcctt ctcctctgcc tcctcgcggt ccccctctcc
    26041 aaacgcctct accaccgcat tcgcctcgcc gacggggaac tccgcgtcgg ccgcgaacgc
    26101 ctggccgtcg cctccctcag ccccgtctcc ctcaccgccg ccgccggcga accgggccgc
    26161 gccggcctgc gcgagtaccg cgcctccctc acccccgacc agctcaagga agcccgtcgc
    26221 cgcaccaacg ccctcacccg gccgcggctg gtgggcgggg cgtgggcagt cccggtcggc
    26281 atggaggagc ttgtggtgga gacggtcgag ggcgcgtccc tggtcctcgc cacgcgggac
    26341 cgggcggggt tgctgggggc gttgacgcgg gcgcgggggt ctgacccttc gccccggggc
    26401 aacgtgcggc ggtgagccgg ccggcggacc tcctgagcac gggcgcgggt gaggcggacg
    26461 ctcggccgtt gcggcggcaa gtggaggcgt cagcacaggg attgggccgc gagaactggt
    26521 gatgcggctg tgtgtccgcg tgggcgagga ggttcaatgg gggcgcgagg tgccgtgggc
    26581 accggaggag gggcggtagg gacatggggt cgcgggagag cagatacacc ctgaaacgct
    26641 ggaagcagac gggcccccgg tggcaccgga agcacggcta ccggggttcg ctgggtgagt
    26701 tccggcacgt cgagatggag actcccgccc ggcttgtcgg accccatttc gtcacggagc
    26761 tccgcgggaa gtccgtcccc ctggtgacct tcagcgggtg gcccttcggg ggtaagccct
    26821 ccctggcgtt cgggcagctc acggtggccg gggagagcgt cccgctgcgg cgcgaccggt
    26881 gggcgctcag caggcagggc cgtgccctgc gcttcgaggt ggctggtcgc gcgtaccgct
    26941 actacgcgac cagccgccgg caccggcacc gcgcgttggc acgggagggc gtggagatag
    27001 tgacccaccg gccgcgccgg ggcgagggga agagcgcgac cgtgagcgtg cgggggcccg
    27061 ccgacgccac ggatgtggcg ctggcggtcc tgctgtgcgg ggtcaacacc cgcaacctca
    27121 ccccgggcgg tgccgtgcgg accttcttct accgggtctt ctcccagctg gcgtgaggcg
    27181 ggggctcagc cccgcccccc acccaccccc aactcccgcg cgatcagcat ccgctggacc
    27241 tcgctggtgc cctcgccgat ttccaggatc ttggagtcgc gccacatgcg ggcgaccggg
    27301 tactcgttca tgaagccgta gccgccgtgg atctgggtgg cgtcgcgggc gttgtcgacg
    27361 gcgacggtgg aggagtagag cttggcggcg gcggcctgct tcttgaaggg ttcgccggcg
    27421 accaggcggc tggcggcgtc gcgccaggcg aggcgggcgg tgtaggcgcg ggtgtccatg
    27481 tcggcgatct tgaactggat ggcctggttg gcgccgatgg gcttgccgaa ggcgtggcgt
    27541 tcggcggcgt acttgaccga ctcgtcgacg cagccctggg cgaggccggt gccgagggcg
    27601 gcgatggcga tgcggccctc gtcgaggatg cggaggaact gggcgtagcc gcggccctct
    27661 tcgccgagga ggttggcggc ggggacgcgg acctcgtcga aggagagttc gcgggtgtcg
    27721 gaggcgttcc agccgacctt ggagtacggg gcggccacgg tgaagccggg ggtgcccgag
    27781 gggacgatga tcgcggagat cagtggggag ccgtcgggct tgcggccggt gacggcggtg
    27841 acggtgacca ggccggtgat gtcggtgccg gagttggtga tgaagcactt gccgccgttg
    27901 atgacccact cgttcgtcgc ctcgtccagg cgggcggtgg tgcgggtgcc cccggcgtcg
    27961 gagcccgcgc cgggctcggt gaggccgaag gcgccgagga tctcgccgga gcacaggcgc
    28021 ggcagccatg cgcgcttctg ctcctcggtg ccgaagaggt ggatcggcat ggcgcccagc
    28081 gagacgcccg cctccagggt gatggcgacg gaggagtcga cgcgggccag ttcctccagg
    28141 gcgatgccga gggcgaggta gtcgccgccc atgccgccgt actcctcggg gaagggcagg
    28201 ccgaacaggc ccatgcggcc catctcgcgg acgatctcgt aggggaactc gtggcgctcg
    28261 tagaggtcgc cgatcttggg ggcgatgaca tcgtgggcga acgcctcgac ggtacggcgg
    28321 agttcctcgt gttcggcgga gagccggtgg tccagggaca tcgggtacga ctcctagtga
    28381 gctgcggcga cggggtacgg ctgcagagca ggggagcgcg ctactcctgg tgggagaggg
    28441 cgcggacggt gcgggagggg ctggggcggc ccagccgggc ggcgagccag tcgctggtgg
    28501 cgacgagcgc gccgaggtcg gtgccggtgt cgatgccgag gccgtgcagc atccagacca
    28561 ggtcctcggt ggcgaggttc ccggtggcgc tctgggcgta cgggcagccg ccgaggcccc
    28621 cggcggaggc gtcgacgacg gtgacgccgt gctggagggc ggcgacggtg ttggagaggg
    28681 cctggccgta ggtgtcgtgg aagtggacgg cgagggcgcc gggttcgacg cccgccgcgt
    28741 gcagggcgcg cagcagggag ccgacctggc cgggggtggc gacgccgatg gtgtcgccga
    28801 gggagagttc gtcgcacccc atggcgtgca gggcggcggc gacccggacc acctgggcct
    28861 cggggaccgg gccctcccac gggtcgccga agcacatcga gaggtagccg cggacccgca
    28921 ggccctcggc cttggcgcgg gtgacgaccg gctcgaacat ggcgagggac tcggcgacgg
    28981 tccggttgag gttgcggcgg gcgaaggtct cggtggcgga ggcgaagacc gcgacgtgcc
    29041 gggcaccgag ggccagcgcc cggtccaggc cccgggcgtt ggggaccagc acgggcaggt
    29101 cggtgccggc ctcgcgcacc tcgtccagca tcgggaagag ctgttcggcg tcggcgagct
    29161 ggggcaccca ctcggggcgg acgaagctgg tcgcctccac ggtggtgagc ccggccgccg
    29221 cgaggcgccg tacgaactcg gccttcacct cggtggggac gaccgtcttc tcgttctgga
    29281 ggccgtcgcg cggaccgacc tcgtggatgc ggacccggga gggcaacccg tcggcgcgga
    29341 ccaccatggg caggcccggc acgccggggc cggtgccggg agtgggtgat gccgtcatgc
    29401 ctgggcctcc tcggcggggg tggcgggtgc ctgtcgtacg acggcggtct cggcgggggc
    29461 ctccccggag ggaacctcgg gggcctccgg cggggtgacg acggcgagga cctggtccat
    29521 ggcgaccgtg gtgccggggg agacgtcgag ttcggtgacg gtgccggcgt gcggggcgca
    29581 gatgaggtgc tccatcttca tcgcctcgac caccagcagg ccctgcccct cctcgacctc
    29641 ctcgccgacg gcgaccttga ccagcgtcac cgtgcccggc atcggcgccg tcagcgcctt
    29701 cgccccggcc gcccggtcgg ccccggccag cgcctcggcg accgggtcga cgtcggtgac
    29761 ctgccaggcg tcgccctccc gggccagcca ctgcccggcc cggcggaagg agtgccgtac
    29821 g
//
