LOCUS       NZ_KZ195583            22574 bp    DNA     linear   CON 07-SEP-2024
DEFINITION  Streptomyces sp. CS227 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ195583
VERSION     NZ_KZ195583.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS227
  ORGANISM  Streptomyces sp. CS227
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6794013)
  AUTHORS   Malmierca,M.G., Gonzalez-Montes,L., Perez-Victoria,I., Sialer,C.,
            Brana,A.F., Garcia Salcedo,R., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Searching for Glycosylated Natural Products in Actinomycetes and
            Identification of Novel Macrolactams and Angucyclines
  JOURNAL   Front Microbiol 9, 39 (2018)
   PUBMED   29441046
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6794013)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Searching for glycosylated natural products in actinomycetes
            isolated from leaf-cutting ants: activation of two silent clusters
            and identification of a novel macrolactam
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 6794013)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAY-2017) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 370.61x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002188355.1-RS_2024_09_07
            Annotation Date                   :: 09/07/2024 02:15:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,017
            CDSs (total)                      :: 5,954
            Genes (coding)                    :: 5,785
            CDSs (with protein)               :: 5,785
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1 (5S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 169
            CDSs (without protein)            :: 169
            Pseudo Genes (ambiguous residues) :: 0 of 169
            Pseudo Genes (frameshifted)       :: 72 of 169
            Pseudo Genes (incomplete)         :: 127 of 169
            Pseudo Genes (internal stop)      :: 12 of 169
            Pseudo Genes (multiple problems)  :: 41 of 169
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:26:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2860442
            Orig. end                         :: 2883016
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ195583.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Salas's laboratory, A.
            Microbiology, University of Oviedo, Spain.
FEATURES             Location/Qualifiers
     region          1..22574
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="15"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22574
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22574
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12574](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12574)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    73..88
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.29"
                     /tool="antismash"
     gene            369..1781
                     /locus_tag="B9W68_RS12395"
                     /old_locus_tag="B9W68_12425"
     CDS             369..1781
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507348.1"
                     /locus_tag="B9W68_RS12395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12425"
                     /product="MFS transporter"
                     /protein_id="WP_087773621.1"
                     /transl_table=11
                     /translation="MRRAARVVGRALRTPVTGPARGIRKVTHAQGAGESGLGRLIELHG
                     VNGAGDVMITVALASTVFFSVPTDEARGRVALYLAVTMLPFTLLAPVVGPLLDRLPHGR
                     RAAMAGAMLARAVLALVLSGAVATGSLEMYPAALGVLVASKAYGVVRSAVVPRLLPQGF
                     SLVKANSRVTLGGLLATGVAAPVGAGLQMIGPGWPLYGACLLFLGGAFLSFRLPPKVDS
                     ARGERRALLAADEQHLAAAVDARWDPVAEPTERDTKEKEKEKDKERRRKGPGLRTVGPA
                     VTHALAANACVRCQSGFLIFFLAFLLREHPLTGQSAAVSLALVGVAAGAGNALGTAVGA
                     WLRARAPEVIIVTVVGVLVAVAVSAAVFFGAAVVAVLGAVAGFTQALAKLSLDALIQRD
                     VPELVRTSAFARSETLLQMAWVVGGAIGIALPLRGPLGLSVGALIVALGWLTTVRALLA
                     SARRGASHPRVA"
     gene            1811..2335
                     /locus_tag="B9W68_RS12400"
                     /old_locus_tag="B9W68_12430"
     CDS             1811..2335
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415563.1"
                     /locus_tag="B9W68_RS12400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12430"
                     /product="DUF2771 domain-containing protein"
                     /protein_id="WP_087773622.1"
                     /transl_table=11
                     /translation="MTSLSRGGAARQFSPATRRGFAVLGAVSAGLLVLSACDKPTAVAT
                     VTIGSDSVNSEATCWNGGSKIDEKKLQECLQDKGEGDSGNGAEVKTVKVDTEADVHIGV
                     DPKIADKGWTILMNGQPLTDASNKTFRTIPGSVFFNQQYGASGDSTVLSILENDGSSAT
                     GLWSFKLEKES"
     gene            2356..3081
                     /locus_tag="B9W68_RS12405"
                     /old_locus_tag="B9W68_12435"
     CDS             2356..3081
                     /EC_number="3.2.2.26"
                     /GO_function="GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010643335.1"
                     /locus_tag="B9W68_RS12405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12435"
                     /product="futalosine hydrolase"
                     /protein_id="WP_087773623.1"
                     /transl_table=11
                     /translation="MRLLVATAVPPERDAVARAFGAPDAPEETALPGAVLLRTAGADVL
                     AAGVGPAAAASATSAALTAARLAGNPYDLVVSAGIGGGFAERAPVGAVVVADRIVAADL
                     GAETPDGFVPVTGLGFGTDVHVPPAALVEAAREAGLVPGAVLTVSTVTGSAERAAELLA
                     RHPSAVAEAMEGFGVAEAAAAHGVPVLEIRAVSNAIGPRDRDAWRIPAALTALTSAFVR
                     LAPAEAGSPFALARARLVP"
     gene            3150..4049
                     /locus_tag="B9W68_RS12410"
                     /old_locus_tag="B9W68_12440"
     CDS             3150..4049
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415567.1"
                     /locus_tag="B9W68_RS12410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12440"
                     /product="1,4-dihydroxy-6-naphthoate synthase"
                     /protein_id="WP_087773624.1"
                     /transl_table=11
                     /translation="MSESGTGGGVRGTADEEAGRLSIAYSPCPNDTFVFDAVAHGRVPG
                     APALDVTFADIDLTNGMAERGEYDVLKVSYAALPWLLDEYALLPCGGALGRGCGPLVLT
                     REASLPGALAGRTVAVPSERSTAYLLFRLWAADQVPGGVGEIVVMPFHEIMPAVRDGKV
                     DAGLVIHEARFTYQNYGLHKLADMGEHWEATTGLPIPLGAIIARRSLGADRLTALTQAL
                     RTSVRMAWDDPAASRPYVLAHAQEMDADVADQHIGLYVNEFTADLGEDGYAAVRGLLTR
                     AAAEGLVPPLAPDALRFP"
     gene            complement(4158..4541)
                     /locus_tag="B9W68_RS32315"
                     /old_locus_tag="B9W68_12445"
     CDS             complement(4158..4541)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642928.1"
                     /locus_tag="B9W68_RS32315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12445"
                     /product="cold-shock protein"
                     /protein_id="WP_003950021.1"
                     /transl_table=11
                     /translation="MPTGKVKWFNSEKGFGFLSRDDGGDVFVHSSVLPAGVEALKPGQR
                     VEFGVVAGQRGDQALSVVLLDPAPSVAAAQRRKPDELASIVQDLTTVLENVSRSLERGR
                     YPDRASGAKVAGMLRAVADQLDV"
     misc_feature    complement(4589..4598)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.3"
                     /tool="antismash"
     gene            4683..4934
                     /locus_tag="B9W68_RS12420"
                     /old_locus_tag="B9W68_12450"
     CDS             4683..4934
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950020.1"
                     /locus_tag="B9W68_RS12420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12450"
                     /product="hypothetical protein"
                     /protein_id="WP_087773625.1"
                     /transl_table=11
                     /translation="MSDTTQQTPAPGDRLVKTGGVVFIIGALATLVTVAPLFLGSDPFP
                     TAAYLVSMLMGVGFLIAGAGLVRQIAAQRRETRAAVEG"
     gene            5210..5890
                     /locus_tag="B9W68_RS12425"
                     /old_locus_tag="B9W68_12455"
     CDS             5210..5890
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415570.1"
                     /locus_tag="B9W68_RS12425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12455"
                     /product="response regulator transcription factor"
                     /protein_id="WP_179230529.1"
                     /transl_table=11
                     /translation="MSRAQTTARVQVIHSSGVLRSALVALLERERFRVTGAPGLSRASS
                     GAPATVTVVDGSCPVGAAHLERRSLQGSAKEPTHATPALAASRPGLGLAGAGGGRAALV
                     VLAGADHPGVLRLAYAAGALGLVDRDGAAGHLATAIRLAAGGGRYVDDGLAMSLLRAMD
                     MPLSPREVRVLSRAAQGDSVAEIARGLCLSHGTVRNYIASATRKVGARNRVDAIRISRA
                     AGWV"
     gene            complement(5865..7838)
                     /locus_tag="B9W68_RS12430"
                     /old_locus_tag="B9W68_12460"
     CDS             complement(5865..7838)
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956283.1"
                     /locus_tag="B9W68_RS12430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12460"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_087773627.1"
                     /transl_table=11
                     /translation="MTRPRDTDGVPSPLLRPALTFARRRKGPLGALAAWSLLESARTFL
                     TGYAVARALDDGFLSGDIRTGLLWLLALAAAALAGGLADAGVFRALGGVIEPLRDSLVR
                     RVVRATLTRAVTSPTPADTARVSRLTAQTEIARDAAGGVLLTVRSFLFTSIGALTGLAA
                     LSPRLLPFVLIPLAAGLTLFAATLRPMAARQRDLLDADEHLAAFAGETDRAARDIAATG
                     AAPSVTAEAAPLITAEATAATALARWSAVRVTALGLAAHLPVATLLLAAPTLLSSGLTP
                     GELLAALTYVTTALLPAVNALLTALGAAGSRLVVVLHRLLGEEVDEAGPSSVPGPSQPD
                     PAHTAPPTPALTAVSAPRHTATATPAQFHAKPSLPGPRPTHPAPLAVTLHGVTFAYGPD
                     AAPVLDHLDLTVGPGEHLLVVGPSGAGKSTLLSLLAGTAHPRNGQIHLAGHTATQARTL
                     GTTARVLVPQEPYVFEAPLHDNLTYLAPDASASRIAEALDTFALTPLAPDPSRSLRPDH
                     LTPSERRRIALARAWLTPTPLLLLDEPTAHLDAGARAATELAFASHPATVITVSHHFPV
                     PEPGQRVLLLDGATPYLGTHGSLLRESALYRELAAGVVEVRPSAVGIRSTASASAWAGG
                     RHAQLPTPPPSPAPLKPTPPPD"
     gene            complement(7835..9610)
                     /locus_tag="B9W68_RS12435"
                     /old_locus_tag="B9W68_12465"
     CDS             complement(7835..9610)
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018896359.1"
                     /locus_tag="B9W68_RS12435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12465"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_306427371.1"
                     /transl_table=11
                     /translation="MTAAPADAGRARATPAPPPADGRLLREAVRRGRGPAALVLAATAL
                     GAAAAVTLPLALGRAVDLLIARADAGFWVLLCTALIATEVATDALVARTGGRTGAATTA
                     WLRRRALAGFLAAPPAATAGTGLPTRLTANALDAGTAPVAAATAAAAGLAPLGGLAGLF
                     LVDPWAGAAFVCGVPLLLLILRALLRDGRAVLTTYQEEQGRMARLLTGALSGAATIAAA
                     GTVRAEERRVLVPLAGMRAAGERTWRVQGRAAGLSGALMPLLVAAVLAVGGVRLVAGHL
                     TPGDLLALSRYAVLAAGAGALAGALNGWVRAKAGTARVETVTTLPPTPYGTRGLPPDGD
                     GTLTLRGVHVTRDGVPLLDSVTLTLPGGTTTALVGPSGAGKSLLAAVAGRLTDPDEGTV
                     LLDGTDLRALSADTLRHAVAYAFERPALFGTTIADAVACGPLPEPDLRRALRRAAADTF
                     TDRLPHGTRTPLPAAPLSGGELQRLGLARAFIRPTRLLILDDATSSLDTVTAHLVTRAL
                     TDTPGTRLTVTHRLTTAAQSDQVIWLDAGRVRGTGPHSALWRDPAYRAVFGAGAGVGGG
                     AGAGVGADNGTGAAE"
     gene            complement(9780..9911)
                     /locus_tag="B9W68_RS12440"
                     /old_locus_tag="B9W68_12470"
     CDS             complement(9780..9911)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611153.1"
                     /locus_tag="B9W68_RS12440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12470"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_008415578.1"
                     /transl_table=11
                     /translation="MALLDLQAMDTPQEEAVGDLATGSQISLLICEYSSLSVTLCTP"
     CDS_motif       complement(9846..9911)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQAMDTPQEEAVGDLAT"
                     /locus_tag="B9W68_RS12440_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9780..9845)
                     /prepeptide="core"
                     /locus_tag="B9W68_RS12440_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="30.10"
                     /molecular_weight="2088.4"
                     /monoisotopic_mass="2087.1"
                     /core_sequence="GSQISLLICEYSSLSVTLCTP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQAMDTPQEEAVGDLAT"
                     /leader_location="[9845:9911](-)"
                     /alternative_weights="2106.4"
                     /alternative_weights="2124.5"
                     /alternative_weights="2142.5"
                     /alternative_weights="2160.5"
                     /alternative_weights="2178.5"
     gene            complement(10001..12574)
                     /gene="lanKC"
                     /locus_tag="B9W68_RS12445"
                     /old_locus_tag="B9W68_12475"
     CDS             complement(10001..12574)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507351.1"
                     /locus_tag="B9W68_RS12445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12475"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_087773628.1"
                     /sec_met_domain="micKC (E-value: 4.9e-224, bitscore: 744.4,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 4.8e-12, bitscore: 44.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 7.4e-05, bitscore:
                     20.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPEYALYSGADRWFYDTPRRAGREDGKEGDRGHRYALALRPAPE
                     GWESAERGDWFSLAPAGRQLPPQGWKIHVSATPDNAEQVLETVAGICQERATAFKFLAG
                     PALLLHRNTKYADRAGSGKFVTVYPAATAACGELAAELADALKGSAGPVVLSDLRWGEG
                     PVHVRYGAFAPRFTRTADGSLVPAVADPAGRLVPDTRGPAFRLPDWVELPDFLRPHAEA
                     RAAQGTTDLPYTVERALHFSNGGGVYAGSHRETGEAVVLKEGRPYAGLAADGADAVTRL
                     EREYAALRALEGLACVPRVHGLHTVGEHRFLAMEFIPGTPLNTVFARRFPLSVAEPAAE
                     ALAEHTAWALRTHQLVTEAVEALHARGIAFGDLHMNNIMVAPDQLSVTLLDFEAATPAA
                     ERRPQIVANPAFVAPPHLRGTEVDRYALACLRLALFVPLTTLLPLDRDKAAHLADLAAD
                     RYGIDRALFDEAVTELAGPARPEAATPRGRPPVSATDWPAARDSMVAALLASTTPERDD
                     RYFPGDIAQFATPAGGQSYGYGAAGVLHALHAVGARCEEAEEWLIRTTRRPASGTPAGF
                     YDGLTGIAWTLDRLGHREDALRLAHLVAAEPLDALGPGLHSGAPGVALALRDLADAADD
                     PALGKAADRAEAAALRPAAPGGKAGLLHGPTGTALLCLRRHARTGEAALLDTAATALRQ
                     ELSRCVPGPDGSLVVSEARRTMPYLGSGSAGIALVLDDYLDRRPDPGFEEARTALLRAT
                     GSAFYIQPGLFRGVAGLLLHLARTTTPGDRAARTALLTRQTALLDWHALTYEGHLAHPG
                     EQLTRLSMDLSTGTAGVLLALAAAHGEPAAHLPFLPPLRRPTDRP"
     gene            complement(12809..13786)
                     /locus_tag="B9W68_RS12450"
                     /old_locus_tag="B9W68_12480"
     CDS             complement(12809..13786)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018469936.1"
                     /locus_tag="B9W68_RS12450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12480"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_087773629.1"
                     /transl_table=11
                     /translation="MTRRTARPLLAATGALALAVTLTACGAGEDTAADAGKDAGATRTV
                     RTAMGEVKVPEAPKRVVVLDTAELDSALTLGVKPVGAVRSDAAAGFASYLPKKELAGIE
                     NVGVIAQPNLEAIAALEPDLILTSKVRDEARYAQLSKIAATVMTENTGYPWKENFQLHA
                     EALGKQKEADRATAAYEKRTAEVTEAVGGPAKAKETEVNVVRFVEGADIRIYGKKNYIG
                     TLLADVGLGRPAITDKATDGFSYDVSPEKIDLADADAVFTSTYGDPEKAKETQTTKSAL
                     WRSLNAVKSGAVHRVEDELWIQGIGYTAAQQILDELEGALTTTS"
     gene            complement(13783..14637)
                     /locus_tag="B9W68_RS12455"
                     /old_locus_tag="B9W68_12485"
     CDS             complement(13783..14637)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950013.1"
                     /locus_tag="B9W68_RS12455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12485"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_087773630.1"
                     /transl_table=11
                     /translation="MTRPTARLAARDLTLAYEDRTVVPGLDLDIPDGRVTVIIGPNACG
                     KSTTLRALGRLLRPVGGAVLLDGTELARLPTRQIAQRIGLLPQTPVAPEAITVADLVAR
                     GRQPHQRWWQQWSEEDERAVSEAMARTATTDLADRPVDALSGGQRQRVWIAMALAQETG
                     LLLLDEPTTYLDLAHQVEVLDLVRRLNREQGRTVVLVLHDLNQAARYADHLIAFREGRV
                     VAEGAPAEVVTAGLVREIFGLECVVVPDPVTGSPLVVPGAPWDARPAPEPALPTREESR
                     ATP"
     gene            complement(14634..15719)
                     /locus_tag="B9W68_RS12460"
                     /old_locus_tag="B9W68_12490"
     CDS             complement(14634..15719)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018896363.1"
                     /locus_tag="B9W68_RS12460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12490"
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="WP_087777828.1"
                     /transl_table=11
                     /translation="MVVLKAEPESARVRPAGYVPVRVGPASLLVPVRAVATGAVLAAVL
                     GVVCVAYLSVGESFVAPGSVVDVLLGRPSPDTLVVGELRLPRMVAGVHVGAAFGIAGAL
                     IQTVARNPLASPDLIGVSQGASAATVAALTFGVTSYTVLPWISVGGGLFAALLVYLLAW
                     RGGLQATRFVLVGVGFAVALRALTTLFLTKGDQTVAQQAQVWMSGSLNGRAWPEAALVG
                     WTLLVALPALVWAARAQRSVTLDDATATSLGARLGRARLGLVLVGVVLASVATGAAGPV
                     DFVALLAPQIARRLTRTAQIPLVCSALAGAVTVVAADLLARRLFAPTELPVGVLTAAVG
                     APYLIWLLVTRHGPRATGGTS"
     gene            complement(15731..16795)
                     /locus_tag="B9W68_RS12465"
                     /old_locus_tag="B9W68_12495"
     CDS             complement(15731..16795)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018896364.1"
                     /locus_tag="B9W68_RS12465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12495"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_087773631.1"
                     /transl_table=11
                     /translation="MPPAPPAAPPLAKAPPTASRPRRDSSVHRAAWTVAALAALLVAVV
                     LSLAVGARTVAPGTVVEALFQGATGPDAEVVREMRLPRTLIGVMVGAALAVAGTALQGI
                     TRNPIADPGILGISQGASVGVVLAIAFAGVHTLAGWVWFAFAGAGLAAVAVYAVAAGGR
                     GGATPVKLALSGAAINALLVSVTTAVLTTSSSALDEFRFWNVGALQGRDAEVAVQVWPF
                     LLVGLALVASSARGLDALALGEDVAKGLGQRVAAVRITAGAGAAVLTGVGVAAAGPIAF
                     VGLAVPHLVRHLVGGDHRWVLPLAALTGPVMLLASDTVGRVLFPPGEVPAGVMTALIGV
                     PFLVALVRGRAVTA"
     misc_feature    16888..16908
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     misc_feature    complement(16889..16909)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.11"
                     /tool="antismash"
     gene            16938..17624
                     /locus_tag="B9W68_RS12470"
                     /old_locus_tag="B9W68_12500"
     CDS             16938..17624
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016472413.1"
                     /locus_tag="B9W68_RS12470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12500"
                     /product="HAD family hydrolase"
                     /protein_id="WP_087773632.1"
                     /sec_met_domain="HAD_2 (E-value: 1.1e-10, bitscore: 40.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEHLTSPSAPAPSDPAVPAARPAPGGAGPVVGFDLDMTLIDSRP
                     GIGAAYRVLAAETGVPIDVDLVVSRLGPPLETELACWFPADQVPAAAARYREVYPSTAI
                     APSLALPGAAEALDAVRAHGGRSLVVTAKNEEHARLHLDHLGLRADLVVGSLWAEAKGV
                     ALRAQGATVYVGDHIGDVRGARAAGAFSVAVATGGCTPDELRTAGAGLVLPDLAAFPAW
                     LAEFAH"
     gene            complement(18015..18557)
                     /locus_tag="B9W68_RS12475"
                     /old_locus_tag="B9W68_12505"
     CDS             complement(18015..18557)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010643354.1"
                     /locus_tag="B9W68_RS12475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12505"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_087773633.1"
                     /transl_table=11
                     /translation="MGDIWTGEKLRLRGVEPEDWRAFRELARDLDGVRAAGLVGPPRSD
                     ESFRGWTAERAGRPPGGEAFRLVVEDLADGGFVGAVTVGEADRRAGRFRMGVEIGRAYR
                     RRGYGREAVTLLLGYMFREERFHKCEVEVYAFNEASLALFRRLGFVEEGRLREHEFVGG
                     VHRDVVVLGITAPEHVG"
     gene            18743..19762
                     /locus_tag="B9W68_RS12480"
                     /old_locus_tag="B9W68_12510"
     CDS             18743..19762
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507354.1"
                     /locus_tag="B9W68_RS12480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12510"
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="WP_256968071.1"
                     /transl_table=11
                     /translation="MKQPAGTAGGAVAEEARPVEGVDGDGPVRGEPGRAAEWWVALRRT
                     PGAFWRDDVSDFAAALTYYAILAVLPALLVVVIAFGLVSPDTAERFVGQVTAWAPGGSG
                     ASLREVLTRVVRVDSTAWTLLVTGGASALWSASSYLAVSRRALHRMYGVRDRRSPWGKA
                     HRIVATALALLALLLVSSLLLMLTEPVAESIGRLLGLDAGVAWAWSVLRWPLLLCLVAC
                     LVVVVFRNGPVAARRRAHSIPGGVLAATLWLTASAGLALYASVLSTYSRLYGSLAGIVV
                     FLVWLWLSNVALLLGAQFTAELCRAEGGPGAPPCHPTDEDDPAGATTSGEPRRPSAGA"
     gene            19882..21816
                     /locus_tag="B9W68_RS12485"
                     /old_locus_tag="B9W68_12515"
     CDS             19882..21816
                     /GO_component="GO:0005777 - peroxisome [Evidence IEA]"
                     /GO_function="GO:0003997 - acyl-CoA oxidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006635 - fatty acid beta-oxidation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008406865.1"
                     /locus_tag="B9W68_RS12485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_12515"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_256968072.1"
                     /transl_table=11
                     /translation="MTLGQLDPIHDSLATDTLRSVITEREIPLRHGSTSASATAADHLL
                     FATRGEEHLRWRELFSTEEFGHRDLPHRQRVELSYRRLRTVAAAIPDPRALALSAPALT
                     ALHEWAGPADPGMATLASIHYNLFLGSLLDHDHEERDLEPWLRMDRIGTFLCTEAEHGN
                     DAVNMETTAEYDRASRQFVLHTPGPGAAKWMPNTSLTGGPKDAVVAARLLVDGRDLGIF
                     LFLTPLSDERGHLPGVSVERLPHTSGAPVDHCATRFHHVRLPHSAMLQGDHGRLSPEGE
                     FESTLGSPRIRFLRSIGRVSMGKLCMSGYSLGATRQAIAVAVRHGSTRLTSGMTKGIRV
                     PLMAHRSHHEPLLDALATTYAATLLHRSVVRQWEVAEEAEREEVDRLVAVAKGWITWAA
                     RETMTTCRERCGAKGLLLTQGIAGQLAANEGTITAEGDNKVIWVKAAGELLMGGFTPKP
                     PSETAPEQRSLRDGTHLQDLMADVERILHERARTRLRTGGVRGNPMARWNGAVTPALEL
                     VAAHAHRLAGEALLEGADRVTAEEAEHIRDLHRLFALRQVAAHSGELLAGERLTAEQVR
                     RLPDEVERVVADLEPHVLALTERFLVPENLPGSDPAGLVEAASEASAAGPESLDGGTGG
                     LRESEPDAA"
     misc_feature    complement(19897..19910)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: strong, score: 22.47"
                     /tool="antismash"
     misc_feature    19933..19935
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 cggggacgga cagcggacgg agcggaccga tgggccgcgt cgacgtccgc gcccgatcgt
       61 ccagggcacg cctacgcgaa ccattctggg ggatcgcgaa gtggcgcgcg gccgggagta
      121 ccgtcgcagg cgcgtgagtg cacgctaccc tctcgcggcc ccgtctccca caccgacgtg
      181 ggaagccggg ccgctcaggg gcgtcggcgg cgcgtcgtac gggtgcgggc gagcccggcg
      241 gcgaggggcg gtgcgggccc gcttcggcca caggggttgc tcgggacact tcgggtcata
      301 ctcggcccgc cagggggcac tatgaccacg tgaccgcctc aggctcgcca cgcgtggagc
      361 gcagcccggt gcgcagggcc gcccgggttg tgggccgcgc gctgcggact cccgtgacgg
      421 gcccggcgcg cggcatccgc aaggtgacgc acgcgcaggg cgcgggcgag tcggggctcg
      481 ggcggctgat cgagctgcac ggggtgaacg gcgccgggga cgtgatgatc acggtggcgc
      541 tggcctcgac ggtcttcttc tcggtgccga cggacgaggc gcggggccgg gtggcgctct
      601 acctggccgt gacgatgctg ccgttcacgc tgctggcgcc ggtggtgggc ccgctcctgg
      661 accggctgcc gcacgggcgg cgggcggcga tggccggggc gatgctggcg cgggcggtgc
      721 tggcgctggt gctgtcgggg gcggtggcga ccgggagcct ggagatgtac ccggcggcgc
      781 tcggcgtcct ggtggcctcg aaggcgtacg gggtggtgcg cagcgccgtg gtgccccggc
      841 tgttgccgca ggggttctcg ctggtcaagg ccaattcgcg ggtgacgctc ggcgggctgc
      901 tggccaccgg ggtggcggcg ccggtcggtg cggggctcca gatgatcggc ccggggtggc
      961 cgttgtacgg ggcgtgtctc ctcttcctcg gcggcgcgtt cctgtcgttc cggctgccgc
     1021 cgaaggtcga ctcggcgcgc ggcgagcggc gggcgctgct ggcggcggac gagcagcatc
     1081 tcgcggcggc ggtggacgcc cgttgggacc cggtggccga gccgacggag agagacacca
     1141 aggagaaaga gaaagagaag gacaaggagc ggcggcggaa ggggccgggg ctcaggacgg
     1201 tcgggccggc ggtgacgcac gcgctggcgg cgaatgcctg tgtgcggtgt cagagcgggt
     1261 tcctcatctt cttcctggcg ttcctgctgc gtgagcatcc gctgacgggg cagagcgcgg
     1321 cggtgtcgct ggccttggtc ggggtggcgg cgggggcggg gaacgcgctg gggacggcgg
     1381 tcggcgcgtg gctgcgggcc cgggcgccgg aggtgatcat cgtgacggtg gtgggggtgc
     1441 tggtggcggt cgcggtgtcg gcggcggtgt tcttcggcgc ggcggtggtg gcggtgctgg
     1501 gggcggtggc cgggttcacc caggcgctgg ccaagctgtc gctggacgcg ctgatccagc
     1561 gtgatgtgcc ggagctggtg cggacgtcgg cgttcgcccg ttcggagacc ttgttgcaga
     1621 tggcgtgggt ggtggggggc gcgatcggga tcgcgctgcc gctgcgcggg ccgctggggc
     1681 tgagcgtggg cgcgctgatc gtggcactcg gctggctgac gaccgtacgg gcgctgctgg
     1741 cgtcggccag acgcggcgcg tcgcaccccc gcgtggcgtg accctccaac gggcccgata
     1801 gccttcgccc atgacatccc tgtcccgcgg cggagccgca cgtcagttca gcccggccac
     1861 gcgccgcggg ttcgccgtcc tcggcgcggt gtccgccggc ctgctcgtcc tgtccgcctg
     1921 cgacaagccg acggcggtcg ccaccgtcac catcggctcc gactcggtga actccgaggc
     1981 gacgtgctgg aacggcggct ccaagatcga cgagaagaag ctccaggagt gcctccagga
     2041 caagggtgag ggcgactccg gcaacggcgc cgaggtgaag accgtgaagg tcgacaccga
     2101 ggccgacgtc cacatcggtg tcgacccgaa gatcgccgac aagggctgga cgatcctcat
     2161 gaacggccag ccgctgaccg acgcgtccaa caagaccttc cggacgatcc ccggcagcgt
     2221 cttcttcaac cagcagtacg gcgcctccgg cgactccacc gtcctctcca tcctggagaa
     2281 cgacggcagc tccgccaccg gcctgtggtc gttcaagctg gagaaggagt cctgacccgc
     2341 ctgcccacgc ccgccgtgcg gctgctcgtc gccaccgctg tcccgcccga gcgggacgcg
     2401 gtggcgcgcg cgttcggggc gccggacgcc ccggaggaga cggcgctgcc cggcgcggtg
     2461 ctgctgcgca ccgcgggcgc cgacgtgctg gccgccgggg tcggcccggc cgccgcggcg
     2521 agcgccacct cggccgcgct gacggcggcc cggctcgcgg gcaacccgta cgacctggtc
     2581 gtctcggccg ggatcggcgg cggtttcgcc gagcgggcgc cggtgggcgc ggtggtggtc
     2641 gcggaccgga tcgtcgcggc cgacctgggc gccgagacac cggacggctt cgttccggtg
     2701 accgggctcg gtttcggtac ggacgtgcac gtgccgcccg ccgcgctggt cgaggcggcc
     2761 cgcgaggcgg ggctcgtgcc cggcgcggta ctcaccgtct ccaccgtgac gggcagtgcc
     2821 gagcgcgccg ccgagctgct ggcccgccac ccgtcggcgg tggccgaggc gatggagggc
     2881 ttcggcgtcg cggaggcggc cgccgcgcac ggcgtaccgg tgctggagat ccgcgccgtc
     2941 tccaacgcga tcggcccccg cgaccgcgac gcctggcgga ttcccgccgc cctcaccgcg
     3001 ctgacctcgg ccttcgtccg cctcgccccc gccgaggcgg ggagcccctt cgccctggcc
     3061 cgcgcccgcc tcgtaccgtg agcgggtagc agtaggcgcg gcacaggcgg cgcgagcagc
     3121 agtagcagca gggaaggcga ggcggcggca tgagtgagag tggtacgggc ggcggcgtac
     3181 gcgggacggc ggacgaggag gccgggcggc tgagcatcgc ctactccccc tgccccaacg
     3241 acaccttcgt cttcgacgcg gtcgcccacg gccgggtccc gggcgcgccc gcgctcgacg
     3301 tgaccttcgc cgacatcgac ttgaccaacg gcatggccga gcgcggcgag tacgacgtcc
     3361 tcaaggtctc gtacgcggcg ctgccctggc tgctcgacga gtacgccctg ctgccgtgcg
     3421 gcggggcgct cggccggggg tgcggcccgc tggtgctgac ccgcgaggcg tccctgccgg
     3481 gggcgctggc cgggcggacg gtggcggtgc ccagcgagcg gtcgacggcc tacctgctgt
     3541 tccggctctg ggcggcggac caggtgccgg gcggggtcgg ggagatcgtg gtgatgccgt
     3601 tccacgagat catgccggcg gtccgggacg gcaaggtcga cgcgggcctg gtcatccacg
     3661 aggcccgctt cacctaccag aactacggcc tgcacaagct ggccgacatg ggcgagcact
     3721 gggaggccac gaccggcctg ccgatcccgc tcggcgcgat catcgcccgc cgctcactcg
     3781 gcgccgaccg cctgaccgcg ctgacccagg cgctgcgcac ctcggtccgg atggcgtggg
     3841 acgaccccgc cgcctcccgc ccgtacgtcc tggcacacgc ccaggagatg gacgcggacg
     3901 tcgccgacca gcacatcggc ctgtacgtca acgagttcac cgccgacctc ggcgaggacg
     3961 ggtacgcggc cgtacgcggc ctgctgaccc gggcggcggc cgagggcctg gtcccgccgc
     4021 tggcgccgga cgccctgcgt ttcccgtaac cggaacggaa cggaacggct ggaacacgta
     4081 cgacaccacg tacgacgaga ccgccggaac acgctgttcc ggcggtctcg tcgtacgtgg
     4141 tgaagggggc cgttcgctca gacgtcgagc tggtcggcga cggcgcggag catgccggcg
     4201 accttggcgc cggaggccct gtccggatag cggccgcgct ccaggctgcg gctgacgttc
     4261 tccaggacgg tggtgaggtc ctggacgatg gaggccagct cgtcgggctt gcggcgctgc
     4321 gcggcggcga ccgagggcgc cgggtcgagg agcaccacgg aaagtgcctg gtcaccgcgt
     4381 tgcccggcga ccacgccgaa ctccacccgc tggccgggct tgagcgcttc gacgccggcg
     4441 ggcagcacgg acgagtgcac gaagacgtcg ccgccgtcgt cgcgggagag gaagccgaag
     4501 cccttctcgc tgttgaacca cttgaccttg ccagtcggca aagcactgtc ccttctcgcc
     4561 ctgccgccgt ccggccgcag tgtcctggtc acatatcagg ggggatgtac ccacggcgaa
     4621 gctatcccat ccgctccacc ccggcgcgga gattacgggg gccggggaac taccctggac
     4681 ccgtgtccga caccacccag cagaccccgg cccccggcga ccgcctcgtg aagaccggcg
     4741 gcgtcgtctt catcatcggc gccctggcga ccctcgtcac cgtcgcgccc ctcttcctcg
     4801 gctccgaccc gttcccgacc gccgcctacc tggtctccat gctgatgggc gtcggcttcc
     4861 tcatcgcggg tgccgggctg gtccgccaga tcgccgcgca gcggcgcgag acccgggcgg
     4921 ccgtcgaggg ctgagcgccg caccccgccc ggcacgctcc ggctcacttc cgaacgttcc
     4981 gggcgccccg cgcgccccct tccgcgccct cccccgctct ccggctcccg ccgatgatgg
     5041 gcccgccgcc gatctgcggc gaccacggac gccgcccgct ccgctggcgg aaccgtttcg
     5101 cctcccggaa tcggcgacgc ccgtcggcca aggctgaaca gcgacggcgc cgcttccgaa
     5161 cccggaacgc gacgccccgc tgagtctccg gaaagcggaa ggcggaacga tgtctcgcgc
     5221 acaaacgacg gctcgcgtac aggtgatcca cagctcgggt gtcctgcgat cggctctggt
     5281 ggccctgctg gaacgcgaaa ggttccgggt cacgggcgcc cccggcctca gcagagcgtc
     5341 gtccggcgcc cccgccacgg tgaccgtcgt cgacggctcc tgtcccgtgg gagcggccca
     5401 cctcgaacgc cgctccctgc aaggctccgc caaggaaccc acccacgcca cccccgccct
     5461 cgcggcctcc cggccggggc tggggctcgc cggggcgggc ggggggcgcg cggcactggt
     5521 ggtactggcc ggggcggacc accccggcgt actccggctc gcctacgcgg ccggcgcact
     5581 cggcctggtc gaccgcgacg gggccgccgg gcacctcgcc accgcgatac gcctggccgc
     5641 cgggggcggt cggtacgtgg acgacgggct ggcgatgagc ttgctccgtg cgatggacat
     5701 gccgctgtcg ccgcgcgagg tgcgggtgct gagcagggcc gcgcaggggg attcggtggc
     5761 ggagatcgcg cgggggctgt gcctgtcgca cgggacggtg cggaattaca ttgcttcggc
     5821 tacgcggaag gtgggggcca ggaaccgggt ggatgcgatt cggatcagtc gggcggcggg
     5881 gtgggtttga ggggggcggg gctggggggt ggggttggca actgagcgtg cctacccccc
     5941 gcccacgccg aggccgaggc ggtactccgg atgcccaccg ccgaaggccg cacctccacc
     6001 acccccgccg ccagctcccg atacaaggcc gactcccgca gcagcgagcc atgcgtcccc
     6061 aggtaagggg tagccccgtc caggagcagg acacgctgcc cgggttcagg caccggaaag
     6121 tgatggctca ccgtgatgac cgtggccggg tgggaagcga aggcgagctc tgtggctgcc
     6181 cgcgcccccg cgtccaggtg ggccgtgggt tcgtccagga ggagcagggg cgtaggggtc
     6241 agccaggctc gggcgagggc gatgcggcgg cgttcggacg gggtgaggtg gtccgggcgg
     6301 agggaacggg acgggtcggg cgcgaggggg gtcagggcga aggtgtcgag ggcttccgcg
     6361 atgcgcgatg cggaggcgtc cggggcgaga taggtgaggt tgtcgtggag gggagcttcg
     6421 aagacgtacg gctcctgggg gacgaggacg cgggcggtcg tcccgagggt gcgggcctgg
     6481 gtggcggtgt ggcccgccag gtggatctgg ccgtttcggg ggtgggccgt gccggcgagg
     6541 agggacagca gagtggattt gccggcgccg ctggggccta cgaccaggag gtgttcgccg
     6601 ggtccgacgg tgaggtcgag gtggtcgagg acgggggcgg cgtcggggcc gtaggcgaag
     6661 gtcacgccgt gcaaggtgac ggcgaggggt gccgggtggg tggggcgagg tcccgggagt
     6721 gagggcttcg catggaactg cgctggcgta gccgtagccg tatgcctagg cgccgacacc
     6781 gccgtaagcg caggcgtggg cggcgccgta tgcgcaggat caggctgtga gggcccaggg
     6841 acggacgacg gtcccgcctc gtccacctcc tcccccagca gccggtgcag cacgaccacc
     6901 agtcgcgacc ccgccgcgcc gagggccgtc agcagggcgt tgacggccgg gaggagggcg
     6961 gtggtgacgt aggtgagggc ggcgaggagt tcgccggggg tgaggccgga cgagaggagg
     7021 gtgggggctg ccaggaggag ggtggctacg gggaggtggg cggcgaggcc gagggcggtg
     7081 acgcggacgg ctgaccagcg ggccagggcg gtggcggcgg tggcctcggc ggtgatgagg
     7141 ggggctgcct cggcggtgac cgacggggct gcgccggtgg ccgcgatgtc gcgggccgcg
     7201 cggtccgtct cgccggcgaa ggcggcgagg tgttcgtcgg cgtcgaggag gtcgcgttgg
     7261 cgggcggcca tggggcggag ggtggcggcg aacagggtca ggccggcagc gagcgggatc
     7321 aggacgaagg ggagcagtct cggggagagg gctgccaggc cggtgagggc gccgatcgag
     7381 gtgaagagga aggaacgcac ggtcagcagg acgccgcctg ccgcgtcgcg ggcgatctcg
     7441 gtctgggcgg tgaggcggga gacgcgtgcc gtgtcggccg gggtgggtga ggtgacggcc
     7501 cgggtcaggg tggcgcggac gacgcggcgg accagggagt cgcgcagggg ctcgatcacc
     7561 ccgccgagcg cgcggaagac cccggcgtcg gcgaggcccc cggcgagggc tgcggcggcg
     7621 agggcgagca gccagaggag gcccgtgcgg atgtcgccgg agaggaaacc gtcgtccagt
     7681 gcgcgggcga cggcgtagcc ggtgaggaag gtacgggccg attcgaggag cgaccaggcg
     7741 gccagcgccc cgagcggacc cttgcggcgg cgggcgaagg tgagggcggg gcgcagcaag
     7801 gggctgggga cgccgtcggt gtcgcgtggg cgggtcactc ggcggccccg gtgccgttgt
     7861 cggccccgac gcctgcgcca gcgccgcccc cgaccccagc ccccgcaccg aagaccgcac
     7921 ggtaagccgg gtcccgccac agggcggagt gcggccccgt cccccgtacc cggcccgcgt
     7981 cgagccagat gacctggtcg gactgggcgg cggtggtgag gcggtgggtg acggtgaggc
     8041 gggtgccggg ggtgtcggtg agggcgcggg tgacgaggtg ggcggtgacg gtgtcgaggc
     8101 tggaggtggc gtcgtccagg atcagcaggc gggtggggcg gatgaacgcc cgcgccaggc
     8161 cgaggcgttg gagttcgccg ccggagaggg gggctgcggg gaggggggtg cgggtgccgt
     8221 gggggaggcg gtccgtgaag gtgtcggcgg cggcgcggcg cagggctcgg cggaggtcgg
     8281 gctcgggcag ggggccgcag gcgacggcgt cggcgatcgt cgtaccgaag agggccgggc
     8341 gttcgaaggc gtacgcgacg gcgtggcgca gggtgtcggc ggagagggcg cgcaggtcgg
     8401 ttccgtcgag gaggacggtg ccctcgtcgg ggtcggtgag gcggccggcc accgccgcca
     8461 gcagggactt gccggcgccg gacgggccga cgagggcggt ggtggtgccg ccggggaggg
     8521 tgagggtgac ggagtcgagg agcggtacgc cgtcgcgggt cacgtggacg ccgcggaggg
     8581 tgagggtgcc gtcgccgtcg ggcgggaggc cgcgcgtccc gtagggggtg ggcggcaggg
     8641 tggtgacggt ctcgacgcgg gcggtgcccg ccttggcgcg gacccagccg ttgagggcgc
     8701 cggccagcgc tccggctccg gcggcgagga cggcgtagcg ggagagggcg aggaggtcgc
     8761 cgggggtgag gtggccggcg acgaggcgta cgccgccgac ggcgaggacg gcggcgacca
     8821 ggagcggcat cagcgcgccg gagaggccgg cggcgcggcc ctggacgcgc caggtgcgct
     8881 cgccggccgc gcgcatcccg gccagcggga cgaggacgcg gcgttcctcg gcgcggacgg
     8941 ttccggcggc ggcgatggtg gcggcgccgg acagggcgcc ggtcagcagg cgggccatgc
     9001 ggccctgttc ctcctggtac gtggtgagga cggcgcggcc gtcgcggagc agggcgcgca
     9061 ggatcaggag gaggagcggg acgccgcaga cgaaggcggc gcccgcccag gggtcgacga
     9121 ggaagagccc ggccaggccg ccgagggggg cgaggccggc ggcggccgcg gtggcggcgg
     9181 cgacgggggc ggttccggcg tcgagggcgt tggcggtgag gcgggtgggc aggccggtgc
     9241 cggcggtcgc ggcggggggc gcggcgagga agccggcgag cgcgcggcgg cgcagccagg
     9301 ccgtggtagc ggcgccggtc cggccgccgg tgcgggcgac cagagcgtcc gtggccacct
     9361 cggtggcgat cagcgcggtg cacagcagga cccagaaccc ggcgtcggcg cgggcgatga
     9421 gcaggtcgac cgcgcggccg agggcgaggg gcagggtgac ggcggcggcg gcgccgagcg
     9481 cagtggccgc gaggacgagg gccgcggggc ccctgccccg gcgtaccgcc tcccggagca
     9541 ggcgcccgtc ggcgggcggc ggggcgggag tggcgcgggc ccggccggcg tcggcggggg
     9601 cggcggtcat ggctgctccg ttcgggcggg cgggcaggca ggcaggaacg cgggggcgtc
     9661 cgggaggggc gcggaacgcg ggaggtcccg ggcgctgggg cgcccgggac caagggttgt
     9721 cgcacgcgcc cggcccgagg gggccgggcg cgcggcggac agccggggtc agccctgcgt
     9781 cacggggtgc agagggtgac gctcagcgag ctgtactcgc agatgagcag cgagatctgg
     9841 ctgccggtgg cgaggtcgcc caccgcctcc tcctgcgggg tgtccatcgc ctggaggtcg
     9901 agaagcgcca tgacgtactc cttcgtgtcg agcggtcgga cgaccgccac ctgggaaaac
     9961 gagtggtgct ggtggtgctg ggtggtgcgc gaccctgggg tcagggccgg tctgtgggcc
    10021 gccggagcgg cgggaggaag ggcaggtgcg cggcgggttc gccgtgggcc gcggccaggg
    10081 cgagcaggac gccggccgtg ccggtggaga ggtccatcga caggcgcgtc aactgttcgc
    10141 cggggtgggc gaggtgtcct tcgtaggtga gcgcgtgcca gtccagcagg gcggtctggc
    10201 gggtcaggag ggcggtgcgg gcggcccggt cgccgggggt ggtggtgcgg gccaggtgga
    10261 ggaggagccc ggccacgccc cggaagaggc ccggctggat gtagaaggcg gagccggtgg
    10321 cccgcaggag ggcggtacgg gcctcctcga agcccgggtc gggccgccgg tccaggtagt
    10381 cgtcgaggac cagggcgatg cccgcgctcc cggagccgag gtacggcatg gtccgccggg
    10441 cctcggagac gacgagcgag ccgtccggtc ccggcacgca acggctcagc tcctggcgga
    10501 gggcggtggc ggcggtgtcg agcagggcgg cctcgccggt acgggcgtgg cggcgcaggc
    10561 agagcagggc ggtgccggtc gggccgtgca gcagtccggc cttgccgccg ggggcggcgg
    10621 ggcggagggc ggcggcctcg gcgcggtcgg cggccttgcc gagggcgggg tcgtcggcgg
    10681 cgtcggccag gtcgcgcagg gccagggcga cgccgggggc gccggagtgc agaccggggc
    10741 cgagtgcgtc gaggggttcg gcggcgacga ggtgggcgag gcgcagggcg tcctcgcggt
    10801 ggccgaggcg gtccagggtc caggcgatgc cggtcagtcc gtcgtagaag ccggccgggg
    10861 tgccggaggc ggggcggcgg gtggtgcgga tcagccattc ctcggcctcc tcgcagcggg
    10921 cgccgacagc gtggagggcg tgcaggacgc cggcggcgcc gtagccgtac gactgtccgc
    10981 cggccggggt ggcgaactgg gcgatgtcgc ccgggaagta gcggtcgtcg cgttcggggg
    11041 tggtggaggc gagcagggcg gccaccatcg agtcgcgggc ggcgggccag tcggtggcgc
    11101 tcaccggggg gcggccacgg ggtgtcgcgg cctccggcct tgccgggcca gcgagttcgg
    11161 tgaccgcctc gtcgaaaagg gcgcggtcga tgccgtaccg gtcggcggcg aggtcggcga
    11221 ggtgggccgc cttgtcgcgg tcgagcggca gcagggtggt gagcgggacg aagagggcga
    11281 ggcggaggca ggccagcgcg taccggtcga cctcggtgcc gcgcaggtgg ggcggggcga
    11341 cgaaggcggg gttggcgacg atctgcgggc ggcgctcggc ggccggggtg gcggcctcga
    11401 agtccagcag ggtgacggag agctggtccg gcgccaccat gatgttgttc atgtgcaggt
    11461 cgccgaaggc gatgccccgg gcgtgcaggg cctccacggc ctccgtgacg agctggtggg
    11521 tgcgcagggc ccaggcggtg tgctcggcga gggcttcggc ggccggctcg gcgacggaga
    11581 gcgggaagcg gcgggcgaag acggtgttga gcggggtgcc cgggatgaac tccatcgcca
    11641 gaaagcggtg ttcgcccacg gtgtgcagtc cgtgcacacg cgggacgcac gccagccctt
    11701 cgagggcgcg cagggccgcg tactcccgct ccaggcgggt gaccgcgtcg gccccgtcgg
    11761 cggcgagccc ggcgtacggc cggccctcct tgagcaccac ggcctcgccg gtctcccggt
    11821 gcgaaccggc gtacaccccg cccccgttgg agaagtgcag ggcgcgttcg acggtgtacg
    11881 ggaggtcggt cgtgccctgg gcggcgcggg cctcggcgtg cgggcgcagg aagtcgggga
    11941 gttccaccca gtcggggagg cggaaggcgg ggccgcgggt gtccgggacg aggcggcccg
    12001 ccggatcggc caccgccggg accagggagc cgtcggcggt gcgagtgaag cggggtgcga
    12061 aggcgccgta gcggacgtgg accgggcctt cgccccagcg caggtcgctg aggacgaccg
    12121 ggccggcgct gcccttgagg gcgtcggcga gttcggcggc cagttcgccg caggcggcgg
    12181 tggcggccgg gtagacggtg acgaacttgc cgctgccggc gcggtcggcg tacttggtgt
    12241 tgcggtggag cagcagggcg ggcccggcga ggaacttgaa ggcggtggcg cgctcctggc
    12301 agatcccggc gacggtctcc aggacctgtt cggcgttgtc cggcgtcgcg gagacgtgga
    12361 tcttccagcc ctggggcggc agttggcgcc cggccggggc gagcgagaac cagtcgccgc
    12421 gctcggcgct ctcccagccc tcgggggcgg ggcgcagggc gagggcgtaa cggtggcccc
    12481 tgtcaccctc cttgccatcc tcacgaccgg cgcggcgcgg ggtgtcgtag aaccagcggt
    12541 cggcgccgct gtagagcgcg tactccggat tcaccggccc ccctcgccgt ctgcgttccc
    12601 gtgccgtgct gtgctgtgcc gtgcgtcgat gacgggttcc acactgcccg tggtcgaacg
    12661 gtgccggtaa gtaacgcttg tcatcggcga gttgtgggaa acgcatggtc cgaacgggtc
    12721 atggcggacg ggctcggagc gtgctgcgag ggggccggta ccgggcccgg aggggctcag
    12781 gaggtggcgg tctcaggagg gggcggtctc aggaggtggt ggtcagtgcc ccctccagct
    12841 cgtccaggat ctgctgggcg gcggtgtagc cgatgccctg gatccacagc tcgtcctcga
    12901 ccctgtggac ggcgccggac ttgacggcgt tcagggagcg ccagagggcg gacttggtgg
    12961 tctgcgtctc cttggccttc tccgggtcgc cgtaggtgga ggtgaagacg gcgtcggcgt
    13021 cggccaggtc gatcttctcg gggctcacgt cgtacgagaa gccgtcggtg gccttgtcgg
    13081 tgatggcggg gcggccgagg ccgacatcgg cgaggagggt gccgatgtag ttcttcttgc
    13141 cgtagatgcg gatgtcggcg ccctcgacga agcggaccac gttgacctcg gtctccttcg
    13201 ccttggccgg gccgccgacc gcctcggtga cctcggcggt ccgcttctcg taggcggcgg
    13261 tggctcggtc ggcctccttc tgcttgccga gggcctcggc gtgcagctgg aagttctcct
    13321 tccaggggta gccggtgttc tccgtcatca cggtggcggc gatcttgctg agctgggcgt
    13381 accgggcctc gtcgcggacc ttggaggtga ggatcaggtc gggctcgagc gccgcgatcg
    13441 cctccaggtt gggctgggcg atgacgccga cgttctcgat cccggccagt tccttcttcg
    13501 gcaggtagct cgcgaagccg gcggcggcgt cggagcggac ggcgccgacc ggtttcacgc
    13561 cgagggtgag cgcggagtcc agctcggcgg tgtccaggac gacgacccgc ttcggcgcct
    13621 ccgggacctt cacctcaccc atcgccgtcc tgaccgtacg ggtggctccc gcgtccttgc
    13681 ccgcgtcggc ggcggtgtcc tcgccggcgc cgcaggcggt gagggtcacg gcgagcgcga
    13741 gggcgccggt ggcggcgagc agcggacggg cggtgcgtcg ggtcatggcg tggccctgct
    13801 ttcttctcgg gtggggagag cgggttccgg cgccggccgg gcgtcccagg gcgctcccgg
    13861 gacgacgagc ggggagccgg tgacggggtc ggggacgacg acgcactcca ggccgaagat
    13921 ctcccggacc aggccggcgg tgacgacctc ggcgggggcg ccctcggcga cgacgcggcc
    13981 ctcgcggaag gcgatgaggt gatcggcgta gcgggcggcc tggttgaggt cgtgcaggac
    14041 gaggacgacg gtgcggccct gctcgcggtt gaggcggcgg accaggtcga ggacctcgac
    14101 ctggtgggcg aggtcgaggt aggtggtggg ctcgtcgagc aggagcaggc cggtctcctg
    14161 ggcgagggcc atggcgatcc agacgcgctg gcgctggccg ccggagaggg cgtccacggg
    14221 acggtcggcg aggtcggtgg tggcggtgcg ggccatcgcc tcgctgaccg cccgctcgtc
    14281 ctcctcggac cactgctgcc accaccgctg gtgcggctgg cggccgcgcg ccaccaggtc
    14341 ggccacggtg atcgcctccg gcgccaccgg agtctgcggc agcagcccga tccgctgcgc
    14401 gatctgccgg gtgggcagcc gggccagttc cgtgccgtcg aggaggacgg cgccgccgac
    14461 cgggcgcagc agccggccga gcgcccgcag ggtggtggac ttgccgcagg cgttgggccc
    14521 gatgatgacg gtgacccggc cgtcggggat gtcgaggtcg aggccgggga cgacggtgcg
    14581 gtcctcgtag gcgagggtga ggtcccgggc ggcgaggcgg gcggtggggc gggtcatgag
    14641 gtgcctccgg tggcgcgggg gccgtgtcgg gtgacgagca gccagatcag gtacggggcg
    14701 ccgaccgccg ccgtgagcac ccccaccggc agttcggtcg gcgcgaagag gcggcgggcc
    14761 agcaggtcgg cggcgaccac ggtgacggcc ccggccagcg cggagcagac cagcgggatc
    14821 tgcgcggtgc gggtgagccg ccgggcgatc tgcggggcga gcagcgcgac gaagtcgacg
    14881 ggcccggcgg cgccggtcgc caccgaggcg agcaccaccc cgacgaggac gaggccgagg
    14941 cgggcgcggc ccaggcgggc gccgagggag gtcgcggtgg cgtcgtccag ggtgacggag
    15001 cgctgggcgc gggcggccca gaccagcgcg ggcagggcga cgagcagggt ccagccgacg
    15061 agggcggctt ccggccaggc gcggccgttg agggaaccgc tcatccacac ctgggcctgc
    15121 tgcgccacgg tctggtcgcc cttggtcagg aagagcgtgg tcagcgcccg cagggccacc
    15181 gcgaacccga ccccgaccag cacgaaccgg gtggcctgga gcccgccccg ccaggcgagg
    15241 aggtagacga ggagcgccgc gaagagcccg ccgcccaccg agatccaggg cagcacggtg
    15301 tacgaggtga cgccgaaggt cagcgcggcg accgtggcgg cgctcgcgcc ctggctgacg
    15361 ccgatcaggt ccgggctggc cagcgggttg cgggccaccg tctggatgag cgcccccgcg
    15421 atcccgaacg ccgccccgac gtggaccccc gccaccatcc ggggcagccg cagctccccc
    15481 acgaccagcg tgtccggaga gggacgcccg agcagcacgt cgaccaccga cccgggcgcg
    15541 acgaagctct cgcccacact caggtacgcg acgcagacca cgcccagcac ggccgccagg
    15601 acggcgccgg tcgccaccgc ccgcacgggg acgaggaggc tggcgggccc cacgcgtacg
    15661 gggacgtacc cggcgggtcg tacgcgggcg gattccggct ccgccttcag caccaccatg
    15721 ctgccgctgc tcacgcggtc accgccctgc cccggacgag tgccaccagg aagggcacgc
    15781 cgatcagcgc cgtcatgacc ccggcgggga cctcgcccgg cgggaagagg acgcggccga
    15841 cggtgtcgga ggcgaggagc atcacggggc cggtcagggc ggccagcggg aggacccagc
    15901 ggtggtcgcc gccgaccagg tggcggacga ggtgcgggac ggcgaggccg acgaaggcga
    15961 tcggcccggc ggcggccacc ccgaccccgg tcagcacggc ggctccggcc cccgcggtga
    16021 tccgtacggc cgcgacccgc tgccccagcc ccttcgccac gtcctccccc agcgccagcg
    16081 cgtccagccc ccgcgccgag gaggccacca gcgccagccc caccagcagg aacggccaca
    16141 cctgtacggc cacctcggcg tcccggccct ggagcgcgcc cacgttccag aagcggaact
    16201 cgtccagggc gctggaactg gtggtcagca cggcggtggt gaccgagacc agcagggcgt
    16261 tgatcgcggc gccgctcagc gccagcttga ccggggtcgc gccgccccgg ccgcccgccg
    16321 cgaccgcgta cacggcgacc gccgcgagcc ccgcccccgc gaacgcgaac cacacccacc
    16381 cggccagggt gtgcaccccc gcgaaggcga tggcgaggac gaccccgacc gaggcgccct
    16441 ggctgatgcc gaggatgccc gggtcggcga tcggattgcg ggtgatgccc tggagagctg
    16501 tcccggcgac ggcgagggcg gcgccgacca tcacgccgat cagcgtgcgc ggcagccgca
    16561 tctcccggac cacctcggcg tccgggcccg tggccccctg gaacagggcc tccacgaccg
    16621 ttccgggggc gaccgtacgg gcgccgacgg ccaggctgag gacgaccgcg accagcagcg
    16681 ccgccagggc cgccaccgtc caggcagccc ggtgtacgga gctgtcccgg cggggccggg
    16741 aggcggtggg cggggccttc gccaggggcg gggcggcggg tggcgcgggg ggcatcgggt
    16801 ccttccgggt cgtctccggg tggcctccgg ggcgtcggcc gggagcggac acgacagcgc
    16861 accaccccaa ttgcccgttc tgcgacggta cttaggcttg gctaagtgta cggccgccgg
    16921 ggctgcacaa tggagggatg cccgagcacc tcacttcccc ctccgcgccc gctccctccg
    16981 accccgccgt accggccgca cgtccggctc cgggcggggc ggggcccgtc gtcgggttcg
    17041 acctcgacat gacgctgatc gactcccggc cgggcatcgg cgccgcctac cgcgtactcg
    17101 ccgccgagac cggcgtcccc atcgacgtcg acctggtcgt ctcccggctc gggccgcccc
    17161 tggagaccga gctggcctgc tggttcccgg ccgaccaggt ccccgccgcc gccgcgcgct
    17221 accgcgaggt ctacccgtcc accgcgatag ccccctcgct cgccctgccc ggcgccgccg
    17281 aggccctgga cgccgtacgg gcccacggcg gacgctcgct cgtcgtcacc gccaagaacg
    17341 aggagcacgc gcggctccac ctcgaccacc tcgggctgcg ggccgacctc gtcgtgggca
    17401 gcctctgggc cgaggccaag ggggtcgcgc tgcgcgcgca gggggccacc gtctacgtcg
    17461 gggaccacat cggcgacgtt cgcggcgccc gggccgccgg cgccttctcc gtggccgtcg
    17521 ccaccggagg ctgcaccccc gacgagctcc gcaccgccgg cgccggcctc gtcctcccgg
    17581 acctggccgc cttcccggcc tggctggccg agttcgccca ctgattcgcc tcgggcgccg
    17641 gctggggctg ggctgccttt ggccaggccc ggttcgccgt gccggtcacg gatggcctca
    17701 agcgccggcc gggctgattt tcggctgggc tctgtcctga ccgtgccggt caaagacggc
    17761 ctcaagcgcc ggccgggctg tgagggtcgc ggtgcgttcg ccggttgggt cgggcggggc
    17821 cgcaccggag gaaccgcgaa tccgacagcc cggccggcgc ttgaggccat ctttgaccgg
    17881 cacggtcgag acggagcccg gcaaccaaca gcccggtcgg cgcttgaggc caaatcggtg
    17941 accggcacgg gcaacaaccg gcacccccag tcgcggcgca gccacaccag gcgaaagggg
    18001 gcgccccgcc cccctcaccc cacatgctcg ggagccgtga tcccgagcac cactacgtca
    18061 cggtgaaccc cgcccacgaa ctcgtgctcc ctcaagcgtc cctcctcgac gaacccgagg
    18121 cgtcggaaca acgcgaggga agcctcgttg aaggcgtaca cctccacctc gcacttgtgg
    18181 aaccgctcct cgcggaacat gtacccgagc agcagagtga cggcctcccg gccgtacccc
    18241 cggcgccggt aggcccgccc gatctcgacc cccatccgga accgcccggc ccgccggtcc
    18301 gcctccccca cggtcaccgc tccgacgaac cccccgtcgg ccagatcctc gacgacgagc
    18361 cggaacgcct cacccccggg cggacgcccg gcccgctcgg cggtccaccc ccggaagctc
    18421 tcgtccgagc ggggcggccc caccaggccg gcggcgcgca ccccgtctag gtcccgggcc
    18481 agctcccgga aggcgcgcca gtcctcgggc tcgaccccgc gcagccgcag cttctcaccg
    18541 gtccagatgt cacccacgac gcccccactc cgtatcgctc acgacccggt cacggtaccg
    18601 gcgcccggcc ccggacaagc cctgagttcc ggcgggcccg cccgcccgcg tagcgtgcac
    18661 cccccgcgcg caggtcggcc gcgcgacgaa cggggtaggc acccctggac ccgtaacggc
    18721 accggtgccg ccaggaggaa cgatgaagca accggctggg acagcgggcg gggccgtcgc
    18781 cgaggaggcg cggccggtgg agggtgtcga cggggacggg ccggtgaggg gcgagccggg
    18841 gcgggcggcg gagtggtggg tggcgttgcg gcggacgccg ggggcgttct ggcgggacga
    18901 cgtgtcggac ttcgcggcgg cgctgaccta ttacgcgatc ctcgccgtgc tgccggcgct
    18961 gctggtggtc gtgatcgctt tcgggctggt gagcccggac acggcggagc ggttcgtggg
    19021 gcaggtgacg gcgtgggcgc cgggcggctc gggggcctcg ttgcgcgagg tgctgacgcg
    19081 ggtggtgcgg gtcgactcga cggcgtggac gctgctggtg acgggcggcg cgagcgcgct
    19141 ctggtcggcc tccagctacc tggcggtctc acggcgcgcg ctgcaccgca tgtacggggt
    19201 acgggaccgt cgttcgccgt ggggcaaggc gcaccggatc gtggcgacgg cgctggccct
    19261 gctggcgctg ctgctggtca gttcgctgct gctgatgctg accgagccgg tggccgagtc
    19321 gatcgggcgg ctgctcgggc tggacgcggg ggtggcgtgg gcgtggagcg tgctgcgctg
    19381 gccgctgctg ctctgcctgg tggcctgtct ggtcgtggtc gttttccgga acggcccggt
    19441 ggccgcccgc cgccgcgccc acagcatccc gggcggtgtc ctcgccgcga cgctctggct
    19501 gaccgcctcg gcggggctcg cgctgtacgc ctcggtgctc agtacgtaca gccggctcta
    19561 cggctcgctc gcggggatcg tcgtcttcct ggtgtggctg tggctctcca acgtcgcgct
    19621 gctgctcggc gcccagttca cggcggagct gtgccgcgcg gaggggggcc cgggcgcgcc
    19681 gccctgccac cccacggacg aggacgatcc cgccggggcc accacttccg gcgaaccccg
    19741 gcggccctcg gccggcgcgt gatccccttc cgctttccgc ccggcgcggg cgtcgcgcac
    19801 gttttgcggg caagagggac gatcacacgc agagggcgcg tacatcccgc caggagctgg
    19861 cctgaactgg tcacttgaca tatgacactt ggtcagttgg accctatcca tgactccctg
    19921 gcgaccgata ctttacgaag tgtgattact gaacgagaga ttccgctccg ccacggctcc
    19981 acctccgcct ccgccaccgc cgccgaccac ctgctcttcg cgacgcgcgg cgaagaacac
    20041 ctgcgctggc gggagctatt cagcacggag gagttcggcc accgggactt gcctcaccgg
    20101 caaagggtgg agttgtccta tcggcgcttg cgtaccgtcg ccgccgcgat acccgaccca
    20161 cgcgcgctcg ccctgagcgc gccggcgctg accgcgctcc acgagtgggc gggcccggcc
    20221 gatcccggga tggccacgct ggcctccatc cactacaacc tcttcctcgg cagcctcctc
    20281 gaccacgacc acgaggagcg ggacctggag ccgtggctcc ggatggaccg gatcggcacg
    20341 ttcctgtgca ccgaggccga gcacggcaac gacgcggtga acatggagac gaccgccgag
    20401 tacgaccgcg cctctcgtca gttcgtcctc cacaccccgg gcccgggggc ggccaagtgg
    20461 atgcccaaca cctcgctgac cggcggcccg aaggacgccg tggtcgccgc ccggctgctg
    20521 gtcgacggcc gcgacctggg catcttcctc ttcctcaccc cgctcagcga cgagcggggc
    20581 catctgccgg gcgtcagcgt cgagcggctg ccgcacacgt ccggcgcgcc cgtggaccac
    20641 tgcgccaccc gcttccacca cgtgcggctg ccgcacagcg cgatgctcca gggcgaccac
    20701 gggcggctca gcccggaggg cgagttcgag agcacgctcg ggagcccccg tatccgcttc
    20761 ctgcgctcca tcggccgggt gtcgatgggc aagctctgca tgtccggcta cagcctgggc
    20821 gccacccggc aggcgatcgc ggtcgccgta cgccacggct ccacgcggct gacctccggc
    20881 atgaccaagg gcatcagggt cccgctgatg gcccaccgca gccaccacga gccgctgctc
    20941 gacgcccttg ccaccacgta cgcggcgacg ctgctgcacc gctcggtggt acgccagtgg
    21001 gaggtggccg aggaggccga gcgcgaggag gtcgaccggc tggtcgcggt ggccaagggg
    21061 tggatcacct gggccgcccg ggagacgatg acgacctgcc gcgagcggtg cggcgccaag
    21121 gggctgctgc tgacgcaggg gatcgcgggc caactcgccg cgaacgaggg caccatcacc
    21181 gccgagggcg acaacaaggt catctgggtc aaggccgccg gtgaactgct gatgggcggg
    21241 ttcaccccga agccgcccag cgagaccgcg cccgagcagc gctccctgcg ggacggtacg
    21301 cacctccagg acctgatggc ggacgtggag cggatcttgc acgagcgggc ccggacccgg
    21361 ctgcgcaccg gcggcgtacg gggcaacccg atggcccgct ggaacggggc ggtcaccccg
    21421 gcgctggagc tggtcgcggc ccacgcccac cggctggccg gggaggccct gctggagggc
    21481 gccgaccggg tcaccgccga ggaggccgag cacatccgcg acctgcaccg cctgttcgcg
    21541 ctgcgccagg tggcggcgca cagcggggag ctgctggccg gggagcggct gacggcggag
    21601 caggtacggc ggctcccgga cgaggtcgag cgggtcgtgg cggacctgga gccccacgtc
    21661 ctcgccctga cggaacgctt cctcgtaccg gagaacctgc ccggcagcga ccccgccggc
    21721 ctggtcgagg ccgcctcgga ggcctccgcc gccggccccg agtcccttga cggcgggacc
    21781 ggcgggctca gggagagcga gccggacgcg gcatgacggg ctgaggcgag cgaggcgcga
    21841 cgcgggacgg cccgccgcgc gtgggcacga cgggccgtcc ttcgtctctc gtcctccgga
    21901 cggcacgccg ggccggaggc gtccgggtca gacccggaag atgtcgagga aggagctcca
    21961 gaagcccttc ctgcgaccgc cgccgtccga ggaggcgggg gcggtgtgct gcggctgcgg
    22021 ggtgggtgcc gcctgctgct gcgggatgcc ccggttctgg agggccgcgg ccatccgggt
    22081 ggccggggtc gggctgaagg cgaccggcag cgagaccagg gcccggtgga aggggcccgg
    22141 gcgccactgg agttcttcct ccgggacgcc gagtgccagg tccggcaggg cgttgaggat
    22201 cttctcgacc gcggtgaccg cgatgacctg cgccgggtcc ttggccgggc aggcgtgcga
    22261 gcccgcgccc caggcgaggt gggcgccgcg tcccgcgctg cggcgggcct cggcgagggc
    22321 ggggtcgctg ttggccccgg cgaaggagat caggacgggg ctgccggcgg gggcgatgac
    22381 accgttgccg aagtccgtgt cctggaccgg gtagtgggcg gcgtagttgg cgatcggggt
    22441 gcggtgccac aggacgtggt cgaccgcctc ctcgaccatc atcccggcgc cccggccgcc
    22501 cgcgccgccg gagagcagtt ccagcagggc gttgccgatg aggttgcgct ccggctcgat
    22561 gccggcgccc atca
//
