LOCUS       NZ_KZ195583            20975 bp    DNA     linear   CON 07-SEP-2024
DEFINITION  Streptomyces sp. CS227 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ195583
VERSION     NZ_KZ195583.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS227
  ORGANISM  Streptomyces sp. CS227
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6794013)
  AUTHORS   Malmierca,M.G., Gonzalez-Montes,L., Perez-Victoria,I., Sialer,C.,
            Brana,A.F., Garcia Salcedo,R., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Searching for Glycosylated Natural Products in Actinomycetes and
            Identification of Novel Macrolactams and Angucyclines
  JOURNAL   Front Microbiol 9, 39 (2018)
   PUBMED   29441046
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6794013)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Searching for glycosylated natural products in actinomycetes
            isolated from leaf-cutting ants: activation of two silent clusters
            and identification of a novel macrolactam
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 6794013)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAY-2017) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 370.61x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002188355.1-RS_2024_09_07
            Annotation Date                   :: 09/07/2024 02:15:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,017
            CDSs (total)                      :: 5,954
            Genes (coding)                    :: 5,785
            CDSs (with protein)               :: 5,785
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1 (5S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 169
            CDSs (without protein)            :: 169
            Pseudo Genes (ambiguous residues) :: 0 of 169
            Pseudo Genes (frameshifted)       :: 72 of 169
            Pseudo Genes (incomplete)         :: 127 of 169
            Pseudo Genes (internal stop)      :: 12 of 169
            Pseudo Genes (multiple problems)  :: 41 of 169
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:26:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2025438
            Orig. end                         :: 2046413
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ195583.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Salas's laboratory, A.
            Microbiology, University of Oviedo, Spain.
FEATURES             Location/Qualifiers
     region          1..20975
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="12"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20975
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20975
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10975](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10975)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    603..618
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.29"
                     /tool="antismash"
     misc_feature    628..643
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.28"
                     /tool="antismash"
     gene            801..1589
                     /locus_tag="B9W68_RS08670"
                     /old_locus_tag="B9W68_08700"
     CDS             801..1589
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950769.1"
                     /locus_tag="B9W68_RS08670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08700"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_179230504.1"
                     /transl_table=11
                     /translation="MTTDAGGTRTRTAGEPATEPTSPVRATRVPKYYRLKRHLLDMTRT
                     LPPGTSVPPERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLT
                     SYTEDMRAQGLEPTSQLLEVGYITADDSLASLLDITAGGRVLRIERLRLASGEPMAIET
                     THLSAKRFPALRRSLVKYTSLYTALYEVYGVRPAEAEETIETSLATPREAALLATDVGL
                     PMLMLSRHSRDESGAPVEWVRSVYRGDRYKFLARLKRPVE"
     misc_feature    complement(1779..1795)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.12"
                     /tool="antismash"
     gene            2063..4279
                     /locus_tag="B9W68_RS08675"
                     /old_locus_tag="B9W68_08705"
     CDS             2063..4279
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0009267 - cellular response to starvation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1185: carbon
                     starvation protein A"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642402.1"
                     /locus_tag="B9W68_RS08675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08705"
                     /product="carbon starvation CstA family protein"
                     /protein_id="WP_087773068.1"
                     /transl_table=11
                     /translation="MAEPAPPASGNRKLSAKSIAVWSLVAVVGAIAWSVLALSRGEEIS
                     AIWMLAAALGSYAIAYRFYSRFIANKVLKVDKNRATPAERLDNGVDFQPTDRRVLFGHH
                     FAAIAGAGPLVGPILAAQMGYLPGTIWIVAGVIFAGAVQDMVTLFFSTRRNGRSLGQMA
                     RDEIGPVGGVAALLAVFMIMIILLAVLALVIVNALAGSPWGVFSIGMTIPIALFMGVYL
                     RTLRPGKVTEVSVLGVALLLLAIVGGGWVAESSMADFFTLEPGTLVIWMVVYGFFASVL
                     PVWMLLAPRDYLSTFMKVGTIVLMAVCVIIAMPTLKMDGITSFATSGAGPVFSGALFPF
                     VFITIACGALSGFHSLVSSGTTPKMVQKETQIRMIGYGAMLTESFVAIMAMIAACIIDP
                     GLYFAINAPVGVIGDTVNSASEAIANLGFTISPDQLAQAAKDVEEGTLLSRTGGAPTFA
                     FGMAEIFSAALGGAGMKAFWYHFAIMFEALFILTTVDAGTRVGRFMLQDTLGNVWKPMR
                     RVSWWPGVWITSAIVVGCWGYFLWVGVHDPLGGINQLFPLFGIANQLLAAVALAVCTTL
                     LIKSGRLKWAWVTGIPLAWDVAVTLTASWQKIFSDNPAIGFFAQRAKYQDGIDAGEVLA
                     PAKSMGDMHTVVTNSTVDGVLSIVFAVLIIIVLVDAGRVCYNAIRKPESVKLAEAPFEQ
                     SKIVAPAGMFATAEEKAELALVGAGAPASVGDGEAPAKQGGDKA"
     gene            4276..4518
                     /locus_tag="B9W68_RS08680"
                     /old_locus_tag="B9W68_08710"
     CDS             4276..4518
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642403.1"
                     /locus_tag="B9W68_RS08680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08710"
                     /product="YbdD/YjiX family protein"
                     /protein_id="WP_003950767.1"
                     /transl_table=11
                     /translation="MSGEAAHHPGRLGVLAHRVRAGVRWIGWYVREVSGETAYEKYAAH
                     VRRHDPDAEVMTRRQFERSRMDAREADPRDGFRCC"
     misc_feature    4826..4840
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 23.01"
                     /tool="antismash"
     misc_feature    4857..4871
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    4865..4878
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     regulatory      4893..4969
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            5130..7499
                     /locus_tag="B9W68_RS08685"
                     /old_locus_tag="B9W68_08715"
     CDS             5130..7499
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966408.1"
                     /locus_tag="B9W68_RS08685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08715"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_087773069.1"
                     /transl_table=11
                     /translation="MTIAPADPSTAEVRAEEIQGPGGALLRTLTDLTADLPDTDPGRVA
                     AAALRGRNAASDEAELRSLATEAAAGLISEDPAYSRLAARLLTRTIAEEAAGQGVTTFT
                     ESVATGHREGLIADRTAAFVTAHATRLDALIDQAADDRFGYFGLRTVHSRYLLRHPHTR
                     QVIETPQHFMLRVACGLAEDDSVRALDEVASLYRLMSALSYLPSSPTLFNSGTRHPQMS
                     SCYLLDSPKDELESIYDRYHQVARLSKHAGGIGLAYSRIRARGSLIRGTNGHSNGIVPF
                     LNTLDASVAAVNQGGRRKGAAAVYLETWHADIEEFLELRDNTGEDARRTHNLNLAHWIP
                     DEFMRRVDADADWSLFSPSDVPELTDLWGDAFDAAYRAAEAQGLAKRTIPARELYGRMM
                     RTLAQTGNGWMTFKDASNRTANQTALPGHTVHSSNLCTEILEVTDDGETAVCNLGSVNL
                     GAFVAGGAIDWERLDEAVRTAVVFLDRVVDINFYPTEQAERSNSRWRPVGLGAMGLQDV
                     FFQLRLPFDSPEAQRLSTRIAERIMLTAYETSCALAERYGPLPNWDRTRTARGVLHPDH
                     YDTDLAWPERWEALRARVAESGMRNALLLAIAPTATIASIAGVYECIEPQVSNLFKRET
                     LSGEFLQVNSYLVEDLKRLGVWDARTREALREASGSVQGFAWIPEELRALYRTAWELPQ
                     RGLIDMAAARTPFLDQSQSLNLFMETPTIGKLSSMYAYAWKKGLKTTYYLRSRPATRIA
                     RAAGGSAPATVPAQAAPDAEAVACSLENPESCEACQ"
     gene            7490..8551
                     /locus_tag="B9W68_RS08690"
                     /old_locus_tag="B9W68_08720"
     CDS             7490..8551
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000805.1"
                     /locus_tag="B9W68_RS08690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08720"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_373557384.1"
                     /transl_table=11
                     /translation="MPVMTTPDTTPAANAHTVGAAKNLLDPGFELTLRPMRYPDFYERY
                     RDAIKNTWTVEEVDLHSDVADLAKLSPGEQHLIGRLVAFFATGDSIVANNLVLTLYKHI
                     NSPEARLYLSRQLFEEAVHVQFYLTLLDTYLPDPADRADAFAAVENIPSIREKAEFCFR
                     WMDSVDKLDQLESQADRRKFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGT
                     NWVFRDETMHMSFAFDVVDTVREEEPELFDDHLQEQVVAMLEEAVEAELQFARDLCGDG
                     LPGMNTESMREYLECVADQRLTRLGFAPVYGSQNPFSFMELQGVQELTNFFERRVSAYQ
                     VAVEGTVSFDDDF"
     gene            complement(8637..10004)
                     /locus_tag="B9W68_RS08695"
                     /old_locus_tag="B9W68_08725"
     CDS             complement(8637..10004)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950763.1"
                     /locus_tag="B9W68_RS08695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08725"
                     /product="cytochrome P450"
                     /protein_id="WP_087773071.1"
                     /sec_met_domain="p450 (E-value: 9.1e-79, bitscore: 263.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAESTTERPAAPGPRTAPLVAGSVPVLGHAPSLVRDPLAFLTGL
                     RDHGDLVRVKLGPKTAYAVCAPELVGALLRNSQEFQVGGPLWENLEVLLGKGVATSNGA
                     DHRRQRRMMQPAFRPERIASYATVMEEEARAMADRWRDGQVVDIGAETFSCAVRVVARS
                     LLEVDSIGAKADRISASLHTVFSGLYRRMILSFGPLHRLPTPANRRFERALADLHHLVD
                     EVIAERHAQGKGADDLLDILLTSEDGEGRPLSDQEIHDHLVSLIVAGAENVASTLAWCF
                     QLLTEHPDQEQRVAEEALSVAPDRPVNFGDLGSLDHTRNVIVESMRIRPAAWIFTRRAV
                     ADTELGGYRIPAGADIIYSAYAMQHDPRSFDRPDVFDPDRWIPERAEKVPQYAMMPFST
                     GNRKCPGDHFSMVEATLMLATVLPRWRLVPVAETDPAPRIGITLQPKRAVFRVESR"
     gene            complement(10001..10975)
                     /locus_tag="B9W68_RS08700"
                     /old_locus_tag="B9W68_08730"
     CDS             complement(10001..10975)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470738.1"
                     /locus_tag="B9W68_RS08700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08730"
                     /product="terpene synthase family protein"
                     /protein_id="WP_087773072.1"
                     /sec_met_domain="T1TS (E-value: 9.9e-51, bitscore: 171.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESRAWLLEKRLMPADKVTRYADELRYTDLIAGYYVGAPRDVISA
                     ISDFSTWFFVWDDQHDRDAVHGRRAAWYRLSAELHTALDAPGDHLAHPEPLVAAFAETV
                     HRLNGFLSPAWNHRFARHFHAIVGAYDQEFENRVTKVTPKVAEYIELRRHTFGHSVWID
                     LLEPTAGREIPESLRTSGPFLTAARHCQDFSAWYNDLCSLPKELAGDDQHNLGISLIRH
                     EGLSLEEAVVEVRKRVENCVTEFEVAEKELRELLAGHLAALPGGAGSAEARSVAEAVGS
                     AVFNMRNWFSSVYWFHHESGRYRVDSWDDRSTPPYVSDLAGDA"
     misc_feature    complement(11011..11024)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.14"
                     /tool="antismash"
     misc_feature    11011..11024
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.17"
                     /tool="antismash"
     misc_feature    11258..11272
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.73"
                     /tool="antismash"
     gene            complement(11362..12018)
                     /gene="def"
                     /locus_tag="B9W68_RS08705"
                     /old_locus_tag="B9W68_08735"
     CDS             complement(11362..12018)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="B9W68_RS08705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08735"
                     /product="peptide deformylase"
                     /protein_id="WP_030695533.1"
                     /transl_table=11
                     /translation="MAQQDTEQQAVAGGVLPVDDEGFVIDTEETEEREAAYRARGTARP
                     ITVVGNPVLHRETKDVTVFDAELAQLVDDMFASQRAAEGVGLAANQIGVDKKVFVYDCP
                     DDEGVRHVGVVCNPVLDELPSERRVLDDSNEGCLSVPTAYAELARPDYAVVRGQDEKGN
                     PIVVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAEGTPRYETVPND"
     gene            complement(12111..13103)
                     /locus_tag="B9W68_RS08710"
                     /old_locus_tag="B9W68_08740"
     CDS             complement(12111..13103)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415712.1"
                     /locus_tag="B9W68_RS08710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08740"
                     /product="hypothetical protein"
                     /protein_id="WP_030695532.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARTAGLRAVALLDRDTGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLKIPGDAAASGEPSGMGLGSAAVRISPEGEAEVVWGRRLDPARIEVQSIPL
                     PSSGRRWGEVILHDGVPHGERTTASGDTYPVFDEIELWAPSPVPTWVVLLEAQAPADRD
                     ALELLAADAGFAAEDWSSSVRLLCRTCSESRMPSDEGGGERHVDPHDHSEPGHPGPLGH
                     RTTSGEGDLWVPERECGIAAPPALVRGLLDGWVADSPDTRAWRDLEEVC"
     gene            complement(13338..13646)
                     /gene="rsrA"
                     /locus_tag="B9W68_RS08715"
                     /old_locus_tag="B9W68_08745"
     CDS             complement(13338..13646)
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642406.1"
                     /locus_tag="B9W68_RS08715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08745"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_030695531.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEVLDHLYEFLDHEMPDSDSNKIRTHFDECSPCL
                     EKYGLEQAVKKLVKRCCGQDDVPADLRDKVISRLDMIRAGQAVPQHDIVPTEAADTP"
     gene            complement(13643..14317)
                     /locus_tag="B9W68_RS08720"
                     /old_locus_tag="B9W68_08750"
     CDS             complement(13643..14317)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="B9W68_RS08720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08750"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_026048295.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGSQDVPEKPEETSAERTARFERDALAFLDQMYSAAL
                     RMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRKKQREPQRS
                     AAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKSALQAIPEEFRIAVYLADVEG
                     FAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGSGASAAEPNERKGA
                     GS"
     gene            complement(14629..15315)
                     /locus_tag="B9W68_RS08725"
                     /old_locus_tag="B9W68_08755"
     CDS             complement(14629..15315)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415707.1"
                     /locus_tag="B9W68_RS08725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08755"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_087773074.1"
                     /transl_table=11
                     /translation="MNVSRSEGVGVPAVLEAGERVSVATDVGEARVTWVRAEVPRLVLA
                     LGHGAGGGVEARDLVALAGVLPGAGVSVALVEQPWRVAGKKVAPAPKTLDKGWEAVWGE
                     VAGEGLPVVAGGRSAGARVACRTGAGLGAAGVLALSFPLHPPGKPERSRAEELLGTGVP
                     TLVVQGGRDPFGRPEEFPGGSYELAEVAYGDHGFAVPKKAPVGQEEALGVITDAVGAWL
                     ERLPVG"
     gene            complement(15562..16434)
                     /locus_tag="B9W68_RS08730"
                     /old_locus_tag="B9W68_08760"
     CDS             complement(15562..16434)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="B9W68_RS08730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08760"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_087773075.1"
                     /transl_table=11
                     /translation="MCGRYAATRSPEDLSQIFGVEKTELSEAVDDQEDGHEAGAAPAPT
                     ETLVPDWNVAPTKEVPAILDRPVKGSDDPRPVRQLRMLTWGLVPSWATSPDGGARMINA
                     RAETVHEKPAYRRAFASRRCILPADGYYEWVTAPEERKLEEEGKRKRSRKQPYFVTPAD
                     GSVFAMAGLYEFWRDPSLPGDHPRAWWVTCSVITTEAEAAPLGVGPEEGPRALADIHPR
                     MPLMLTPDKWDAWLDPSKTDVGEVRELLGAPPEGLMRAYPVATAVSNVRNNGPGLVSEL
                     DGPEVGTLF"
     gene            16524..17246
                     /locus_tag="B9W68_RS08735"
                     /old_locus_tag="B9W68_08765"
     CDS             16524..17246
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950755.1"
                     /locus_tag="B9W68_RS08735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08765"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_087773076.1"
                     /transl_table=11
                     /translation="MQSTTAAPATDLWDRVTGTQTAPEFWLVVATGVAALAVVLWGPAW
                     RPARNAITIAHEGGHGLIALVTGRTLEGIRLHSDTSGLTVSRGKPTGPGMILTALAGYT
                     APSLLGLGGAWLLASGHITLLLWVATALLLALLVMVRNAYGVLTVLIAGGLFVAVSWLA
                     GSEVQALFAYAAVWFLLIGGVRPVFELQSKRRRGGAPDSDADQLARLTHAPAAIWLFLF
                     HAVALCSLIGGGGWLLGR"
     gene            17289..18641
                     /gene="aroA"
                     /locus_tag="B9W68_RS08740"
                     /old_locus_tag="B9W68_08770"
     CDS             17289..18641
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642411.1"
                     /locus_tag="B9W68_RS08740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08770"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_087773077.1"
                     /transl_table=11
                     /translation="MTLNPVSTPLWPAPYATGAVEATVQVPGSKSVTNRALVLAALAAE
                     PGWLRRPLRSRDTVLMAEALRTLGVGIEETVSSDSAAPGSALAGGGEAWRIIPSGLRGP
                     ATVDVGNAGTVMRFLPPLATLADGDIRFDGDPRSYERPLHGVIDALRALGARIDDDDRG
                     SLPMTVHGTGSLDGGTVEIDASSSSQFVSALLLSAPRFNQGVEVRHIGPRLPSMPHIRM
                     TVDMLRRVGAQVDEPESGGEPNVWRVTPGALLGRDLTVEPDLSNAQPFLAAALVTGGRV
                     IVPDWPAHTTQPGDRLREIFTRMGGSCELTEAGLVFTGSGRVHGIDVDLGEVGELTPGI
                     AAVAALADGESVLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLRIRPRPLRGGV
                     FHTYDDHRMATAGAILGLVVKGVEIENVATTAKTLPDFPDLWTGMLDGTGQ"
     gene            18659..19675
                     /gene="rsgA"
                     /locus_tag="B9W68_RS08745"
                     /old_locus_tag="B9W68_08775"
     CDS             18659..19675
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rsgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966421.1"
                     /locus_tag="B9W68_RS08745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08775"
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="WP_047141045.1"
                     /transl_table=11
                     /translation="MRRYGKNPDEDDIRVRPSRRGSRPRTHTRPKHEDAAEGMVLTVDR
                     GRITCLVEGRTVTAMKARELGRKAAVVGDRVALVGDLSGQKDTLARIVRIEERASVLRR
                     TADDDDPYERVVVANADRLAIVTALADPEPRPRMIDRCLVAAYDGGLEPVLVLTKSDLA
                     SPDSLLDTYRALGVPYVVTSREELEDGSAVERVRELLDGHVTAFVGHSGVGKTTLVNAL
                     VPEEQRRVTGHVNAVTGRGRHTTVSALALPLADAAPGSWVIDTPGVRSFGLHHVEPSRV
                     IHAFPDLEPGTEECPRGCSHDEPECALDQWVADGHADPARLHSLRRLLATRERREGD"
     gene            19803..20126
                     /locus_tag="B9W68_RS08750"
                     /old_locus_tag="B9W68_08780"
     CDS             19803..20126
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950752.1"
                     /locus_tag="B9W68_RS08750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08780"
                     /product="multidrug efflux SMR transporter"
                     /protein_id="WP_003950752.1"
                     /transl_table=11
                     /translation="MAWLLVVVAGLLETGFAVCLKLSHGFTRLWPTIAFAAFALGSFGL
                     LTLALKRLDVGPAYAVWTGIGAAGTATYGMIFLGDVVSVLKIVSITLVICGVIGLQLSG
                     SAQ"
     gene            complement(20092..20706)
                     /locus_tag="B9W68_RS08755"
                     /old_locus_tag="B9W68_08785"
     CDS             complement(20092..20706)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893589.1"
                     /locus_tag="B9W68_RS08755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_08785"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_087773078.1"
                     /transl_table=11
                     /translation="MSEVHAALLIAAEAHLARRAWSAVRMGEVAASAGVSRQTLYNEFG
                     SKEGLARALARQAADGYLAGIERTLARPAADPRERLRAAADWTVAAARPGTLLRSLLTG
                     CWGDPLPAPRPARTTATAPAQRRAELPLPGPGDLLAAARDRAVAVLNESAPPRTDPREL
                     ARECECVLRLALSRIVAPPVAGGAGVGRRRVTGPSPRAGGR"
ORIGIN
        1 ggggagggcg tcggagccgg tcgccttctt cagcatctcc tggttgtaga ccgcgacgcg
       61 ggcaccggcg tagtagggca cgcagtactg cttgccctcg aaggtgcagg tgtcggtgag
      121 gccctggatc caggtgtccg agttctcgta cttcttgggg tcgatctcgg cgagggcgcc
      181 gttgaggatg tactgcatcg tctcggtgtt gccgagctcg acgacgtccg ggaacttgtc
      241 cccgccgagg gcggtgtcga gcttcttggc cttgtcggcc cagccctggt actggacgtt
      301 caccttgaca ttggggtact tcttcttgaa ctgcgcgttg acgtccttga ccagctccgg
      361 ccaggtgctc tgggcgtcga ccatcagcca gacggtcagg ttttccttgc ggtcctcggg
      421 cttggcgttg ctcgccgtct ccgagtcccc gcacgccgcg agaccggcca tcatgccagc
      481 gacaccgatg gccgcaatga gcttgcgctt cacgtcaccc tcctcaggga accctctacc
      541 ccccacccgc agcgaatgac atcgaagacg agttactgcc gtgggactgg gatctggtct
      601 ttaatggtgt agaccagtaa gccggagctt ggcctagacc tttaggggtg tcaagggtgt
      661 ataagaaggg cagtcacgtc cgttatcgga ccgacacctg agggagtccg gaccggcgat
      721 caccggccgt gccacgatgt gatccgcgac agacggagga gccggtgacg gcagcagcac
      781 aggagccgga gaggcggagc atgacgacgg acgcgggcgg cacgaggacc cggacggccg
      841 gcgaacccgc caccgaaccc accagtccgg tacgggccac gcgggtgccc aagtactacc
      901 gtctcaagcg tcacttgctc gacatgacgc ggacgctgcc gccgggcacc tccgtgcccc
      961 ccgagcgtac gctcgccgcc gagttcgaca cctcgcggac cacggtgcgc caggcgctcc
     1021 aggagctggt ggtcgagggc cggctcgaac gcatccaggg caagggcacc ttcgtcgcca
     1081 agcccaaggt ctcccaggcg ctccagctga cctcgtacac cgaggacatg cgcgcccagg
     1141 gactggagcc cacctcgcaa ctgctggagg tcggctacat caccgccgac gactcgctcg
     1201 cctccctgct cgacatcacc gccggcggcc gggtgctgcg catcgagcgg ctccggctgg
     1261 ccagcggcga gccgatggcg atcgagacca cccacctctc cgccaagcgc ttccccgcgc
     1321 tgcgccgctc cctggtcaag tacacctccc tctacacggc gctctacgag gtctacgggg
     1381 tccgcccggc cgaggccgag gagaccatcg agacctcgct cgccaccccg cgcgaggcgg
     1441 ccctgctcgc caccgacgtg ggcctgccga tgctcatgct ctcccgccac tcccgcgacg
     1501 agtcgggcgc gccggtggag tgggtgcgct cggtctaccg cggcgaccgg tacaagttcc
     1561 tggcccgcct gaagcggccg gtggagtagg ccggcggcag gctcgcggac gacagggcgg
     1621 cacccctcca ccggaggtgc cgccctgtcg cgttccggcc acgggagccg acgcgcgaca
     1681 cgggcgcgca tggccggaaa gcacccccac tcaccccgcc tgacccccgc cgggcaattc
     1741 gctcgtacgt gtgtgcactt ccgcgcatga ccgccgggtc gcgaggggta cgcagtcccc
     1801 agcggaaggt cacggttggg gggcgatcga cgagggggca ctcgggcggg gaggcgcccc
     1861 gcgggggaca aatgcgcggg gagccgtgcg taagggacgg ggacgcggcg gcagcggcgg
     1921 ccggttgcgc gggacgggaa gtcgttgccg ttccgatacg cggacagggg gtgtccaagc
     1981 ccggacccgt cgcctacatt tccgacgcat tgcaggagtt cagcgcaggt gtttccgcca
     2041 gcgctcatgt gaggggacca tcatggccga gccggctcca cccgcctccg gaaaccggaa
     2101 gctgtccgcc aaatccatcg ccgtctggtc gctggtcgcc gtggtcggcg ccatcgcctg
     2161 gagcgtgctg gcgctctccc ggggcgagga gatctccgcc atctggatgc tggcggcggc
     2221 cctcggctcg tacgccatcg cgtaccgctt ctactcgcgg ttcatcgcca acaaggtcct
     2281 gaaggtcgac aagaaccggg ccaccccggc ggagcgcctg gacaacgggg tcgatttcca
     2341 gccaaccgac cgtcgggtgc tcttcggcca tcacttcgcg gcgatcgcgg gtgcgggccc
     2401 gctggtcggc ccgatcctgg cggcccagat gggctacctg ccgggcacca tctggatcgt
     2461 cgcgggcgtg atcttcgccg gcgccgtcca ggacatggtc accctcttct tctccacccg
     2521 gcgcaacggc cgttcgctcg gccagatggc ccgggacgag atcggcccgg tcggcggtgt
     2581 cgccgccctg ctcgcggtct tcatgatcat gatcatcctg ctggcggtgc tggccctcgt
     2641 catcgtcaac gcgctggccg gctcgccgtg gggtgtcttc tccatcggca tgaccatccc
     2701 gatcgccctc ttcatgggcg tctacctgcg cacgctgcgc cccggcaagg tcaccgaggt
     2761 ctccgtcctc ggcgtcgccc tgctgctgct ggcgatcgtg ggcggcggct gggtcgccga
     2821 gtcctccatg gcggacttct tcaccctgga gccgggcacc ctggtcatct ggatggtggt
     2881 ctacggcttc ttcgcctcgg tgctgccggt ctggatgctg ctcgccccgc gtgactacct
     2941 ctccaccttc atgaaggtcg gcacgatcgt gctgatggcg gtctgcgtca tcatcgcgat
     3001 gccgacgctg aagatggacg gcatcacctc cttcgcgacc agcggcgcgg gcccggtctt
     3061 ctccggcgcc ctcttcccgt tcgtcttcat caccatcgcc tgcggcgcgc tctccggctt
     3121 ccactccctg gtctcctcgg gcaccacccc gaagatggtc cagaaggaga cccagatccg
     3181 gatgatcggg tacggcgcga tgctcaccga gtcgttcgtc gccatcatgg cgatgatcgc
     3241 cgcctgcatc atcgaccccg gcctgtactt cgcgatcaac gccccggtcg gcgtcatcgg
     3301 cgacacggtc aacagcgcct cggaagccat cgccaacctc ggcttcacca tcagccccga
     3361 ccaactggcc caggcggcca aggacgtcga ggaagggacg ctgctgtcgc ggaccggcgg
     3421 cgcgccgacc ttcgccttcg gtatggccga gatcttctcg gccgcgctgg gcggcgccgg
     3481 gatgaaggcg ttctggtacc acttcgcgat catgttcgag gcgctcttca tcctcaccac
     3541 cgtcgacgcc ggtacgcggg tcggccgctt catgctccag gacaccctgg gcaacgtctg
     3601 gaagccgatg cgccgcgtca gctggtggcc gggcgtctgg atcacctcgg cgatcgtggt
     3661 cggctgctgg ggctacttcc tctgggtcgg cgtccacgac ccgctgggcg gcatcaacca
     3721 gctcttcccg ctcttcggta tcgccaacca gctgctggcc gccgtcgcgc tggccgtctg
     3781 caccacgctg ctgatcaagt cgggccgcct caagtgggcc tgggtgacgg gcatcccgct
     3841 cgcctgggac gtggcggtca cactcaccgc gagctggcag aagatcttct cggacaaccc
     3901 ggccatcggc ttcttcgccc agcgcgccaa gtaccaggac ggcatcgacg cgggcgaggt
     3961 gctggccccg gccaagtcga tgggcgacat gcacaccgtg gtgaccaact ccaccgtgga
     4021 cggcgtcctg tcgatcgtct tcgcggtgct gatcatcatc gtcctggtcg acgcgggccg
     4081 cgtctgctat aacgcgatcc gcaagcccga gtcggtcaag ctggccgagg cgcccttcga
     4141 gcagtcgaag atcgtcgccc cggccggaat gttcgccacc gccgaggaga aggccgaact
     4201 ggccctcgtc ggcgccggag cccccgcctc cgtcggcgac ggcgaggcgc ccgcaaagca
     4261 gggcggcgac aaggcatgag cggtgaggcg gcccaccacc ccggacgcct cggcgtcctg
     4321 gcccaccgcg tacgcgccgg cgtccgctgg atcggctggt acgtccggga ggtgtcgggc
     4381 gagacggcgt acgagaagta cgccgcgcac gtgaggcgcc acgacccgga cgccgaggtg
     4441 atgacccgca ggcagttcga acgcagccgc atggacgccc gcgaggcgga cccgcgcgac
     4501 ggattccgct gctgctgaac accggttgaa gccgccggcc cccgaccgag ggggccggcg
     4561 gcttcgccgt tccatgggcc gggggccctg gcggccgccg gcccggtccg ggcgtacgct
     4621 ctccgaggtc gccgcggagc tccgcgcgcc gcccgtgagg tccctccggg ctcgcccccg
     4681 gggcctcccc ctccgcgccg gtggcccctc aggagcccgc tgacggcctg tccggcgggc
     4741 gccggtgacc cgcccgaggg cgcctcagcg aggttcgggc atccggtgcg ggtggggtcg
     4801 aatggcccac ctcacagcac acccgacaca agatatgggg ccgcttcgcg agcgcggcac
     4861 aagatgtatg ctcatgctcg ctgtcgccgc aggggaatcc ggtggaagtc cggaactgtc
     4921 ccgcaacggt gtgttggtgc gctttcgcgt acccacgagt ccgaggacct gccgaacagc
     4981 gcacccggcc gtccggtccg ggtgccgatg tcgtccgggc ctcgtggaat gggctcgcgg
     5041 acgcgtgcgg agccgtgtgc ctcaagcccg gcgtcccgcc cgtacccgcc gccctccgcg
     5101 aggctccgag ccgagcgagg gagagcttca tgaccatcgc gccagccgat ccgtcgacgg
     5161 ccgaggtgcg ggccgaggag atccagggcc ccgggggcgc gctgctgcgt accctcaccg
     5221 acctcacagc ggatctcccc gacaccgacc ccggccgggt cgccgccgcc gcgctccggg
     5281 gccgcaacgc cgcctcggac gaggccgagc tgcggtcgct cgcgacggag gccgccgccg
     5341 gtctgatctc cgaggacccc gcctactccc ggctcgccgc ccgcctgctg acccgcacca
     5401 tcgccgagga ggccgcgggc cagggcgtca ccaccttcac cgagtcggtc gccaccggcc
     5461 accgcgaggg cctgatcgcc gaccgcaccg cggccttcgt gaccgcgcac gccacccggc
     5521 tcgacgccct gatcgaccag gcggccgacg accgcttcgg ctacttcggc ctgcgcaccg
     5581 tgcacagccg ctacctgctg cgccaccccc acacccgcca ggtcatcgag acgccccagc
     5641 acttcatgct ccgcgtggcc tgcggcctcg ccgaggacga ctcggtccgg gccctcgacg
     5701 aggtcgcctc gctctaccgg ctgatgagcg ccctctccta cctgccctcc tcccccaccc
     5761 tcttcaactc cggcacccgg cacccgcaga tgtcctcctg ctacctgctg gactccccca
     5821 aggacgagct ggagtcgatc tacgaccgct accaccaggt cgcccggctc tccaagcacg
     5881 ccggcggcat cggcctcgcc tactcccgta tccgcgcccg gggttcgctg atccgcggca
     5941 ccaacgggca ctccaacggc atcgtgccgt tcctcaacac gctcgacgcc tcggtggccg
     6001 ccgtcaacca gggcggccgg cgcaagggcg cggccgcggt ctacctggag acctggcacg
     6061 ccgacatcga ggagttcctg gagctgcggg acaacaccgg cgaggacgcc cggcgcactc
     6121 acaacctcaa cctcgcgcac tggattccgg acgagttcat gcgccgggtc gacgccgacg
     6181 ccgactggtc gctcttctcc ccctcggacg tgcccgagct gaccgacctg tggggcgacg
     6241 ccttcgacgc ggcgtaccgg gcggccgagg cacagggcct ggccaagcgg accatcccgg
     6301 cgcgcgagct gtacggccgg atgatgcgca ccctcgcgca gaccggcaac ggctggatga
     6361 ctttcaagga cgcctccaac cgcaccgcga accagacggc gctgccgggc cacacggtgc
     6421 actcctcgaa cctgtgcacg gagatcctgg aggtcaccga cgacggcgag acggccgtct
     6481 gcaacctcgg ctcggtcaac ctcggcgcct tcgtcgcggg cggcgcgatc gactgggagc
     6541 ggctggacga ggcggtgcgc accgccgtgg tcttcctcga ccgcgtggtc gacatcaact
     6601 tctacccgac cgagcaggcc gagcgctcca actcccgctg gcggccggtg gggctgggcg
     6661 cgatgggact ccaggacgtc ttcttccagc tccggctgcc cttcgactcc cccgaggccc
     6721 agcggctctc cacgcggatc gccgagcgca tcatgctcac cgcctacgag acctcctgcg
     6781 ccctggccga gagatacggc ccgctgccga actgggaccg cacccgcacc gcccggggcg
     6841 tcctccaccc ggaccactac gacaccgacc tggcctggcc cgagcggtgg gaggcgctgc
     6901 gcgcccgggt cgcggagagc ggcatgcgca acgcgctgct cctcgcgatc gccccgacgg
     6961 ccaccatcgc ctcgatcgcc ggtgtctacg agtgcatcga gccgcaggtc tccaacctct
     7021 tcaagcgcga gacgctgagc ggggagttcc tccaggtcaa ctcctacctg gtggaggacc
     7081 tgaagcggct cggcgtctgg gacgcgcgca cccgcgaggc gctgcgtgag gcgagcgggt
     7141 cggtgcaggg cttcgcgtgg attcccgagg agctgcgggc gctgtaccgc accgcctggg
     7201 agctgccgca gcgcggcctg atcgacatgg cggcggcccg gaccccgttc ctggaccaga
     7261 gccagtcgct caacctgttc atggagacgc ccaccatcgg caagctcagc tcgatgtacg
     7321 cgtacgcctg gaagaagggg ctgaagacca cgtactacct gcggtcccgc ccggccacgc
     7381 ggatcgcccg cgccgccggc ggctccgccc ccgccaccgt cccggcgcag gcggcccccg
     7441 acgcggaggc cgtcgcctgc tccctggaga accccgagtc ctgcgaggca tgccagtaat
     7501 gaccaccccc gacaccaccc cggcagcgaa cgcgcacacc gtcggcgcgg cgaagaacct
     7561 gctcgatccc ggcttcgagc tgaccctgcg cccgatgcgg tacccggact tctacgagcg
     7621 ctaccgggac gcgatcaaga acacctggac cgtcgaggag gtcgacctcc actccgacgt
     7681 cgccgacctg gcgaagctct ccccgggtga gcagcacctg atcgggcggc tggtcgcctt
     7741 cttcgccacg ggtgactcga tcgtcgccaa caacctcgtg ctgaccctgt acaagcacat
     7801 caactccccc gaagcgcggc tctacctgag ccggcagctc ttcgaggagg ccgtgcacgt
     7861 ccagttctat ctgacgctgc tcgacaccta cctgcccgac cctgccgacc gcgcggacgc
     7921 cttcgcagcg gtggagaaca tcccctcgat ccgcgagaag gcggagttct gcttccgctg
     7981 gatggactcg gtggacaagc tggaccagct ggagagccag gcggaccgcc gcaagttcct
     8041 gctcaacctg atctgcttcg ccgcctgcat cgaggggctc ttcttctacg gggcgttcgc
     8101 ctacgtgtac tggttccgct cgcgcgggct gctgcacggc ctggcgaccg gtaccaactg
     8161 ggtcttccgt gacgagacga tgcacatgag cttcgccttc gacgtggtcg acacggtccg
     8221 cgaggaggag ccggagctct tcgacgatca cctccaggag caggtcgtcg cgatgctcga
     8281 ggaggccgtc gaggcggagc tccagttcgc ccgcgacctg tgcggtgacg gcctgcccgg
     8341 catgaacacc gagtcgatgc gcgagtacct ggaatgcgtc gccgaccagc ggctcacccg
     8401 gctgggcttc gccccggtgt acggctcgca gaacccgttc tccttcatgg agctgcaggg
     8461 tgtgcaggag ctgaccaact tcttcgagcg ccgggtctcg gcctaccagg tcgcggtcga
     8521 gggcaccgtc tccttcgacg acgacttctg accggtcccg ccccgcgaac gcccgccgcc
     8581 cggcccctcg tcctgggggc cgggcggcgg gcgtcggtgc ttcggcgcgg tgcgggtcag
     8641 cggctctcga cccggaagac cgcgcgcttg ggctggaggg tgatgccgat ccggggcgcc
     8701 gggtcggtct cggcgacggg gacgagccgc cagcggggca gcacggtggc gagcatcagc
     8761 gtggcctcga ccatgctgaa gtggtcgccg gggcatttcc ggttgcccgt gctgaacggc
     8821 atcatcgcgt actgcggtac tttttcggcc cgttcaggaa tccaccggtc cgggtcgaag
     8881 acgtccggcc ggtcgaatga gcgcggatcg tgctgcatcg catacgcgct gtagatgatg
     8941 tccgccccgg ctggaatgcg atagccaccg agttccgtgt cggcgacggc acggcgggtg
     9001 aatatccacg ccgcaggccg tatccgcatg gattcgacga tgacattgcg ggtgtggtcg
     9061 agggagccca gatcgccgaa attgaccggt cggtccggtg ccacggatag tgcctcctcg
     9121 gccacccgct gttcctggtc cggatgttcg gtgaggagct ggaagcacca ggcgagtgtc
     9181 gaggcgacgt tttcggcccc cgcgacgatc agcgagacga gatggtcgtg aatctcctga
     9241 tcgctgagcg gcctgccttc gccgtcctcg gaggtgagca ggatgtcgag gaggtcgtcg
     9301 gcgcccttgc cctgcgcgtg ccgctcggcg atcacctcgt cgacgaggtg gtggaggtcg
     9361 gccagcgccc gctcgaagcg ccggttggcg ggggtcggca gccggtgcag cggcccgaag
     9421 gagaggatca tccgccggta caggccgctg aagacggtgt gcagcgaggc gctgatccgg
     9481 tccgccttgg cgccgatcga gtcgacctcc agcagcgagc gggcgaccac ccgcaccgcg
     9541 cagctgaacg tctcggcgcc gatgtcgacc acctgcccgt cccgccagcg gtcggccatc
     9601 gcccgcgcct cctcctccat cacggtcgcg tacgaggcga tccgctcggg ccggaaggcg
     9661 ggctgcatca tgcggcgctg gcggcggtgg tcggccccgt tgctggtggc cacgcccttg
     9721 ccgagcagca cttcgaggtt ctcccagagc ggcccgccga cctggaactc ctgggagttg
     9781 cgcagcagcg ccccgaccag ctcgggcgcg cagaccgcgt acgccgtctt cgggccgagc
     9841 ttcacgcgga ccaggtcgcc gtggtcgcgc agcccggtga ggaaggccag cgggtcgcgg
     9901 accaggctcg gggcgtggcc gaggacgggc acgctgccgg ccaccagggg cgcggtgcgc
     9961 gggcccgggg cggcggggcg ttcggtggtg gattcggcgc tcacgcgtca cctgccaggt
    10021 cgctgacgta gggcggggtg ctccggtcgt cccagctgtc gacgcggtag cggccggact
    10081 cgtggtggaa ccagtagacg gaggagaacc agttgcgcat gttgaagacg gccgacccga
    10141 cggcctcggc gacggacctg gcctcggcgg agccggctcc tccaggcagt gcggcgagat
    10201 gtccggcgag gagttcccgc aattccttct ccgccacctc gaattcggtg acgcagttct
    10261 ccacgcgttt cctcacctcc accacggcct cttcgagcga cagtccctca tggcgtatga
    10321 gactgattcc cagattgtgc tggtcgtcgc cggcgagttc tttcgggagt gagcagaggt
    10381 cgttgtacca ggcggagaaa tcctggcagt gccgggccgc ggtcaggaac ggaccactgg
    10441 tccggagcga ttcgggaatc tcgcgccccg cggtgggttc gagcaggtcg atccagacgg
    10501 agtggccgaa ggtgtgacgg cgcagttcga tgtattcggc gaccttcggg gtgactttgg
    10561 tgacgcggtt ctcgaattcc tggtcgtagg cgccgacgat ggcgtggaaa tggcgggcga
    10621 aacggtggtt ccaggcgggg ctgaggaagc cgttcagccg gtggacggtc tcggcgaagg
    10681 ccgcgaccag cggctccggg tgcgccaggt ggtcgccggg ggcgtccagc gcggtgtgca
    10741 gttcggcgct gagccggtac caggcggcgc gccgcccgtg gacggcgtcg cggtcgtgct
    10801 ggtcgtccca gacgaagaac caggtgctga agtcggaaat cgccgagatg acgtccctcg
    10861 gcgctcctac gtagtagccg gcgatgaggt cggtgtagcg gagctcgtcc gcatagcggg
    10921 tgaccttgtc ggcgggcatc agtcgctttt cgagcagcca ggcgcgggac tccacctgaa
    10981 gctttggcca atactcatga cgatgtcgcg gaaacgcttg ttcgatcacg ggcaacgcca
    11041 gcgcctcggg caccgaagtc gtctgcgccc gtgcggtgct gtgtgggaaa gcaggcacga
    11101 acaaacccct ttcatccgct ttctgccggt gccccctgcc gggcggggca ccgcgcggtg
    11161 gtgtatcccc ccgccctttc cattgagcac cacaactgac cggtctggaa acagatttgc
    11221 tccattcgcc acccctcgcc gacccgaaga tcgccatacc tgtccgaaaa ttgatcatgg
    11281 cccacgacac accaccgccc cgcctcccgt gagggagagc ggggcggtgc gggtccgcgg
    11341 cggcgggccg ccgggggcgc ctcagtcgtt ggggaccgtc tcgtagcgcg gggtgccctc
    11401 ggccatctgc cgcagggcgt ccttgcgctc gcgcttggag agccggtcga tgtagaggta
    11461 gccgtacagg tggtccgtct cgtgctggag gcagcgggcg aagtagccgg tgccgcgcac
    11521 cacgatcggg ttgcccttct cgtcctggcc gcgcaccacc gcgtagtcgg ggcgggccag
    11581 ctccgcgtag gcggtgggga ccgagaggca cccctcgttg gagtcgtcga ggacgcggcg
    11641 ctcggagggc agctcgtcca ggaccgggtt gcagaccacg ccgacgtggc gcacgccctc
    11701 gtcgtccggg cagtcgtaga cgaagacctt cttgtccacg ccgatctggt tggcggccag
    11761 gcccacgccc tccgccgccc gctggctggc gaacatgtcg tccaccagct gggccagctc
    11821 cgcgtcgaag accgtcacgt ccttcgtctc gcggtgcagc accgggttgc ccaccacggt
    11881 gatcggacgc gcggtgcccc gggcgcggta ggccgcctca cgctcctcgg tctcctcggt
    11941 gtcgatgacg aacccctcgt cgtcgaccgg cagcacaccg cccgccaccg cctgctgctc
    12001 cgtgtcctgc tgcgccatgt ccgcttccgc gccttcctgg gaacccgttg tccgtgcccg
    12061 tacagcctac gcgggggccg gggtgcgggt ggccgccagg acgggcccgg tcagcacacc
    12121 tcttcgaggt cgcgccaggc gcgggtgtcc gggctgtcgg cgacccagcc gtcgagcagg
    12181 ccgcgcacca gggcgggcgg ggcggcgatg ccgcactcgc gctcggggac ccacaggtcg
    12241 ccctcgccgg aggtggtccg gtggcccagc gggccggggt ggcccggttc gctgtggtcg
    12301 tgcgggtcga cgtggcgctc gccgccgccc tcgtcgctcg gcatccggct ctccgaacag
    12361 gtccggcaga gcagccgcac cgacgaggac cagtcctcgg cggcgaaccc ggcgtcggcc
    12421 gccagcagct ccagcgcgtc ccggtcggcc ggggcctgcg cctccaggag caccacccag
    12481 gtcggcaccg gggagggcgc ccacagctcg atctcgtcga agacgggata ggtgtcaccc
    12541 gaagcggtgg tccgctcgcc gtgcgggacc ccgtcgtgca ggatcacctc gccccagcgg
    12601 cggccggagg agggcagcgg gatcgactgg acctcgatgc gggccgggtc cagccgccgg
    12661 ccccagacca cctcggcctc cccctcgggg gagatccgca cggcggcgct gcccagcccc
    12721 atccccgacg gctcaccgga ggccgccgcg tccccgggga tcttcagtcc gtacgcctgc
    12781 caggcgcggc gggccagcgg ccagtcctgg agggcggtgg cggcgatacc gacgttccac
    12841 cagtcggggg cgccggtgtc ccggtccagc agcgcgacgg cgcgcaggcc cgcggtacgg
    12901 gcctgttccc agtcgtggcg gaacttgtgg agcagggcga ggttgaacca ggactcggag
    12961 agccacggct ccaggtcggc ggcgcgcgtg agcagggcgc ccgcgtcctc gtaacggccg
    13021 tcgccgatca aggtgaacgc tcggtcggtc gcctgccgcc aggaggcgga ggggcggtgc
    13081 cgtcccttgc cgaagatcct cacgattccc gcctgccggt gtccggtccc ttcgggcccc
    13141 ccacccgtgt gcaggcgctg agcctgggga cggggtacct cttcgcatcc aaccacggac
    13201 ggttggggcg ccgctcatta cccatgggtt acccactggc gtgaggtgca gaccttctcg
    13261 gaccgggtcg ctctatcgag tgacttgccc ggggagcgtc cggcctgtat ccgcccgctc
    13321 ccgggccgtc ccggacgtca gggcgtgtcc gccgcttccg tcgggacgat gtcgtgctgc
    13381 gggaccgcct ggcccgcccg gatcatgtcc aggcggctga tcaccttgtc gcgcaggtcc
    13441 gcggggacgt cgtcctgacc gcagcaccgc ttgaccagct tcttgacggc ttgctccagg
    13501 ccgtacttct ccaggcaggg agagcactcg tcgaagtgcg tgcggatctt gttggagtca
    13561 ctgtcgggca tctcgtggtc gaggaactcg tagagatggt cgaggacttc cgagcaatcc
    13621 gtctcgtgcg gctctccgca gctcatgacc ccgcaccttt ccgctcgttc ggttccgccg
    13681 cgctcgcccc ggaaccggcg gggaccagcc cgcgctcacg ggcgtagtcc tccagcatgc
    13741 cgcgcagctg gcggcggccg cggtgcaggc gggacatcac cgtcccgatg ggtgtaccca
    13801 tgatgtccgc gatctccttg tacgcaaacc cctcgacatc ggccagatag acggcgatgc
    13861 ggaactcctc ggggatcgcc tggagggcgg acttcacgtc ggagtcggga aggtggtcca
    13921 gcgcctggga ctcggcggag cgcagaccgg tcgacatgtg cgactcggca cgcgccagct
    13981 gccagtcctc gatctcctcg gcggcgctgc gctggggctc acgctgcttc ttgcggtacg
    14041 agttgatgaa ggtgttggtg agaatccggt agagccatgc cttgaggttg gtgccctcac
    14101 ggaactggtg gaacgacgcg tacgccttgg cgtaggtctc ctggaccagg tcctcggcgt
    14161 cggccgggtt gcgggtcatc cgcagggccg ccgagtacat ctggtcgagg aaggcgagcg
    14221 cgtcccgctc gaaccgcgcg gtccgctccg ccgaggtctc ctcgggcttc tcgggtacgt
    14281 cctggcttcc cgcgtcggtc cccgtgaccg gacccacctc cttcagcgct gtggcgggcc
    14341 cgccggccgg accgcccgaa tcggaggata gaccacgctc ctggacttcc cggcgatcgc
    14401 cgccggagcc agtgcgcacg ggcgcctgca gcaccgacca ctccaggtcg gtggcgcgct
    14461 cgcggctcgg gcagatggtc gaacccatgc ggcggacttc ctctcgtgat caacgctgcc
    14521 gaagcacctt cgccccgcac aacagccgcc acccgctcgg cattcccgtc cccgcgcgag
    14581 gccgcctccg cccgccgcgc gaccgcctcg ccccaccgcg tgcccgcctc agcccaccgg
    14641 cagccgctcc agccacgccc ccaccgcgtc cgtgatcacc ccgagcgcct cctcctggcc
    14701 gacgggcgcc ttcttcggca cggcgaaccc gtgatcgccg tacgccacct ccgccagctc
    14761 gtagctcccc ccggggaact cctccggccg cccgaacggg tcccgcccgc cctgcaccac
    14821 cagcgtcggc acccccgtcc cgagcagctc ctcggcccgg ctccgctccg gcttccccgg
    14881 cggatgcaac ggaaagctca gcgcgagcac cccggcggcc cccagccccg ccccggtccg
    14941 gcaggccacc cgcgcccccg cactgcgccc gcccgccacc accggcagcc cctccccggc
    15001 cacctcgccc cagaccgcct cccacccctt gtccagcgtc ttcggcgccg gcgccacctt
    15061 cttccccgcc acccgccagg gctgctccac caacgccaca ctcaccccgg cccccggcaa
    15121 cacccccgcc aacgccacca gatcccgagc ctccacccca cccccggccc catgcccgag
    15181 cgccagcaca agccgaggca cctccgcccg cacccaggtg acccgcgcct cccccacatc
    15241 cgtggcgacg ctcacccgct cccccgcctc cagcacagcg ggaacaccca caccttcaga
    15301 cctcgatacg ttcatccggc catcctgccc cgccgaccac accccgctca cggcaccacc
    15361 ggcgacgccc cggccagcac acctccaagc ccgaccggga aaatccagcc cggccggcgc
    15421 ttgagaggcc acacttcaag cccggccggc gcttgaggcc acacttcaag cccggccggc
    15481 gtttgaggcc atctgtgacc ggcacggtcg ccacggcgag cgcccaatga cagcccggcc
    15541 ggcgcttgag gcccccgcac gctagaacag cgtgcccacc tcaggcccgt ccagctcgga
    15601 caccagcccg ggcccgttgt tccgcacatt gctcaccgcg gtggccacgg gataggcccg
    15661 catcaacccc tcaggcggcg cccccaacag ctcccgcacc tcccccacat ccgtcttcga
    15721 cggatcaagc cacgcatccc acttgtccgg cgtcagcatc aacggcatcc ggggatggat
    15781 gtcggccagc gcccgaggcc cctcctcggg ccccaccccg agcggcgccg cctccgcctc
    15841 ggtcgtgatg acggaacacg tcacccacca ggcgcgcgga tggtccccgg gcaacgaggg
    15901 gtcacgccag aactcgtaca gcccggccat ggcgaagacc gacccgtcgg cgggcgtcac
    15961 gaagtagggc tgcttacggc tccgcttccg cttcccctcc tcctccagct tccgctcctc
    16021 cggagcggtc acccactcgt aatagccgtc ggcggggagg atgcagcgcc gtgaggcgaa
    16081 ggcccggcgg taggcgggct tctcgtggac ggtctcggcc cgggcgttga tcatccgggc
    16141 gccgccgtcg ggcgaagtcg cccaggaggg gaccagcccc caggtcagca tccgcaactg
    16201 ccgtacgggg cgcgggtcgt cgctcccctt gaccggccgg tcgaggatgg cgggaacctc
    16261 cttggtgggc gccacgttcc agtcggggac gagggtctcg gtgggcgcgg gggccgcccc
    16321 cgcctcgtgg ccgtcctcct ggtcgtccac cgcctcgctc agctcggtct tctcgacgcc
    16381 gaagatctgg ctgaggtcct cggggctccg ggtggccgcg taccgtccgc acatacgtgc
    16441 cagactgcca ggccgtgcca ccggaccgcc accagcgggg gcccggggcc gcgcgtccca
    16501 ccctcgcgag gagccgcccg agtatgcaga gcaccaccgc cgccccggcc accgatctgt
    16561 gggaccgcgt caccgggacc cagaccgccc ccgagttctg gctggtcgtg gcgaccggcg
    16621 tggcggcgct cgccgtggtc ctgtggggcc cggcctggcg cccggcccgg aacgcgatca
    16681 ccatcgccca cgagggcggc cacggcctga tcgccctggt caccggccgc acgctggagg
    16741 ggatacgcct ccactcggac acctcgggac tgaccgtcag ccggggcaag ccgaccggcc
    16801 cgggcatgat cctcaccgcc ctcgccggct acaccgcccc ctccctcctc ggtctcggcg
    16861 gcgcctggct gctggcctcg gggcacatca cgctgctgct ctgggtggcg acggccctgc
    16921 tcctcgccct cctcgtgatg gtccgcaacg cctacggcgt gctgacggtg ctgatcgccg
    16981 gcggcctctt cgtggcggtc tcctggctgg ccggctcgga ggtgcaggcc ctcttcgcct
    17041 acgcggcggt ctggttcctg ctgatcggcg gggtacgccc ggtcttcgag ctccagtcga
    17101 agcggcggcg cggcggcgcc ccggactccg acgccgacca gctcgcccgg ctgacccacg
    17161 ccccggcggc catctggctc ttcctcttcc acgcggtggc gctctgctcc ctgatcggcg
    17221 ggggcggctg gctgctcggc cggtgaccgt gcacgggtgg aaggggctgg gcgcactaag
    17281 gtgacggcat gaccctgaac cccgtatcca cccccctctg gcctgccccg tacgcgaccg
    17341 gagccgtcga ggcgacggtc caggtaccgg ggtccaagtc ggtcaccaac cgcgcgctgg
    17401 tgctggccgc gctcgccgcc gagccgggct ggctgcgccg gccgctccgc tcgcgcgaca
    17461 ccgtgctgat ggcggaggcg ctgcgcaccc tcggcgtggg catcgaggag accgtctcgt
    17521 ccgactcggc ggcgccgggc agcgccctgg ccgggggcgg cgaggcatgg cggatcattc
    17581 cgtcgggcct gcgcggcccc gccaccgtcg acgtcggcaa cgccggcacc gtgatgcgct
    17641 tcctgccgcc gctcgccacc ctcgccgacg gcgacatccg cttcgacggc gacccgcgct
    17701 cctacgagcg tccgctgcac ggcgtgatcg acgcgctgcg cgcgctgggc gcccggatcg
    17761 acgacgacga ccggggcagc ctgccgatga cggtgcacgg cacgggctcg ctcgacggcg
    17821 gcacggtgga gatcgacgcc tcctcgtcct cccagttcgt cagcgccctg ctgctgtcgg
    17881 cgccccgctt caaccagggc gtcgaggtcc ggcacatcgg cccgcggctg ccgtcgatgc
    17941 cgcacatccg gatgaccgtc gacatgctgc gccgggtcgg cgcccaggtg gacgagccgg
    18001 agtcgggcgg cgagcccaac gtctggcggg tcaccccggg cgccctgctc ggccgggacc
    18061 tcaccgtcga gccggacctg tcgaacgccc agcccttcct ggcggctgcg ctggtcaccg
    18121 gcggccgtgt gatcgtcccg gactggccgg cccacaccac gcagccgggt gaccggctgc
    18181 gggagatctt caccaggatg ggtggttcct gcgagctgac cgaggcgggc ctggtcttca
    18241 ccggctcggg ccgcgtccac ggcatcgacg tggacctcgg cgaggtcggc gagctgaccc
    18301 cgggcatcgc ggccgtcgcg gccctggccg acggcgaatc cgtcctgcgg ggcgtcgccc
    18361 acctgcggct ccacgagacg gaccggctgg ccgcgctcac caaggagatc aacgagctgg
    18421 gcggcgacgt cacggagacc gccgacggcc tgcgcatccg cccccgcccg ctgcgcggcg
    18481 gcgtcttcca cacctacgac gaccaccgga tggcgaccgc cggtgcgatc ctgggactgg
    18541 tggtgaaggg cgtcgagatc gagaacgtcg ccaccaccgc gaagaccctg cccgacttcc
    18601 ccgacctgtg gaccggcatg ctcgacggga ccgggcagtg acggccggga gctgaacgat
    18661 gcgccgttac ggaaagaacc ccgacgagga cgacatccgc gtccgcccca gccgccgggg
    18721 cagccgcccc cgtacccaca cccgcccgaa gcacgaggac gccgccgagg gcatggtgct
    18781 caccgtggac cggggccgga tcacctgcct ggtcgagggc cgcacggtga ccgcgatgaa
    18841 ggcccgcgag ctgggccgca aggcggcggt ggtgggcgac cgggtcgcgc tggtcgggga
    18901 tctctccggg cagaaggaca ccctggcgcg catcgtgcgg atcgaggagc gcgcctcggt
    18961 gctgcgccgc acggccgacg acgacgaccc gtacgagcgg gtggtcgtcg ccaacgccga
    19021 ccggttggcg atcgtcacgg cgctggccga tccggagccg cggccccgga tgatcgaccg
    19081 ctgcctcgtc gccgcgtacg acggcggcct ggagccggtc ctggtgctga ccaagtcgga
    19141 cctggcctcc cccgactccc tgctggacac ctaccgggcg ctgggcgtgc cgtacgtggt
    19201 gaccagccgg gaggagctgg aggacggttc ggccgtggag cgggtccggg agctgctgga
    19261 cggccatgtc accgccttcg tgggccactc gggtgtcggc aagacgacgc tggtgaacgc
    19321 gctggtcccc gaggagcagc ggcgggtcac cggccacgtc aacgcggtga ccggccgcgg
    19381 ccggcacacc acggtctcgg cgctggcgct gccgctggcc gacgccgccc ccggcagctg
    19441 ggtgatcgac acgccgggtg tgcgctcgtt cgggttgcac cacgtcgagc cctcccgcgt
    19501 gatccacgcc ttccccgacc tggagccggg cacggaggag tgcccgcgcg ggtgcagcca
    19561 cgacgagccg gagtgcgcgc tcgaccagtg ggtggccgac ggccacgccg acccggcccg
    19621 cctccactcg ctgcggcggc tgctggcgac gcgggagcgg cgcgagggcg actgacccgg
    19681 gcgcgacctg cggcgcgacg agccgggccg ggtcgcctgc cgcaccggat ggcacgggca
    19741 taatcgcccg aagccgtaca aggtgcgcgc gggatcgttt cggcgggcgg aagggctctc
    19801 tcatggcatg gctgctggtc gtcgtcgcgg ggctgctgga gacgggtttc gccgtctgcc
    19861 tcaagctgtc gcacgggttc acccggctgt ggccgacgat cgccttcgcc gcgttcgccc
    19921 tcggcagctt cggcctgctg accctggccc tcaagcgcct ggacgtgggc ccggcctacg
    19981 cggtgtggac cggcatcggc gccgccggca ccgccaccta cggcatgatc ttcctcggcg
    20041 acgtggtctc ggtcctgaag atcgtctcga tcaccctcgt catctgcggc gtcatcggcc
    20101 tccagctctc gggctcggcc cagtgacccg ccgccgcccc acccccgcac cccccgccac
    20161 cggcggcgcc acgatccggg agagggccag gcgcagcacg cattcgcact cgcgggccag
    20221 ttcgcggggg tcggtccggg gcggcgccga ttcgttgagc acggccacgg cgcggtcgcg
    20281 ggcggcggcg aggaggtcgc cggggccggg cagcgggagt tcggcacggc gctgggcggg
    20341 ggcggtggcg gtggtgcggg ccgggcgcgg ggcgggcagc gggtcgcccc agcagccggt
    20401 cagcagggag cgcagcaggg tgccggggcg ggcggcggcc accgtccagt cggcggcggc
    20461 gcgcagccgc tctcgggggt cggcggcggg gcgggccagg gtccgttcga tcccggccag
    20521 gtagccgtcg gccgcctgcc gggccagcgc gcgggcgagc ccttccttgc tgccgaactc
    20581 gttgtagagc gtctgccggg agaccccggc cgaggccgcg acctcgccca tccgcaccgc
    20641 gctccacgcg cgacgggcca ggtgggcctc ggcggcgatc agcagggctg cgtggacttc
    20701 cgacacggtg gcctccccgg cacgggtcgt gcggggaagt ctggcgcggg cgcgggtcgt
    20761 gtcaaggggg tgtgcgggcg aggtgcggac gccgcgcccg ccggtgaccg gatggcccgg
    20821 cgcggccgga gatcgatact gtttcgccca tggccgacta tcacgatgat ctgcgtctcg
    20881 cccatgtgct ggcggacgcc gccgacgcga ccacgatgga gcggttcaag gccctcgacc
    20941 tgaaggtgga gaccaagccg gacctcactc ccgtg
//
