LOCUS       NZ_KZ195583            22286 bp    DNA     linear   CON 07-SEP-2024
DEFINITION  Streptomyces sp. CS227 scaffold00001, whole genome shotgun sequence.
ACCESSION   NZ_KZ195583
VERSION     NZ_KZ195583.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. CS227
  ORGANISM  Streptomyces sp. CS227
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6794013)
  AUTHORS   Malmierca,M.G., Gonzalez-Montes,L., Perez-Victoria,I., Sialer,C.,
            Brana,A.F., Garcia Salcedo,R., Martin,J., Reyes,F., Mendez,C.,
            Olano,C. and Salas,J.A.
  TITLE     Searching for Glycosylated Natural Products in Actinomycetes and
            Identification of Novel Macrolactams and Angucyclines
  JOURNAL   Front Microbiol 9, 39 (2018)
   PUBMED   29441046
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6794013)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Searching for glycosylated natural products in actinomycetes
            isolated from leaf-cutting ants: activation of two silent clusters
            and identification of a novel macrolactam
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 6794013)
  AUTHORS   Malmierca,M.G., Mendez,C., Olano,C. and Salas,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAY-2017) Biologia Funcional, Area de Microbiologia,
            Universidad de Oviedo, Julian Claveria S/N, Oviedo, Asturias 33006,
            Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 370.61x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002188355.1-RS_2024_09_07
            Annotation Date                   :: 09/07/2024 02:15:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,017
            CDSs (total)                      :: 5,954
            Genes (coding)                    :: 5,785
            CDSs (with protein)               :: 5,785
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1 (5S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 169
            CDSs (without protein)            :: 169
            Pseudo Genes (ambiguous residues) :: 0 of 169
            Pseudo Genes (frameshifted)       :: 72 of 169
            Pseudo Genes (incomplete)         :: 127 of 169
            Pseudo Genes (internal stop)      :: 12 of 169
            Pseudo Genes (multiple problems)  :: 41 of 169
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:26:25
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1704140
            Orig. end                         :: 1726426
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KZ195583.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Salas's laboratory, A.
            Microbiology, University of Oviedo, Spain.
FEATURES             Location/Qualifiers
     region          1..22286
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="10"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22286
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22286
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12286](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12286
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(191..730)
                     /locus_tag="B9W68_RS07220"
                     /old_locus_tag="B9W68_07250"
     CDS             complement(191..730)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470926.1"
                     /locus_tag="B9W68_RS07220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07250"
                     /product="hypothetical protein"
                     /protein_id="WP_087772875.1"
                     /transl_table=11
                     /translation="MKIRSALSALALVAGAGFGVIGTATAATAAPAPTSTVAEVGAAAT
                     KITHAQATSRFSSSGITWSSSGGCSNRNVSTCTSFDQLNLATAQGAQTLKSASGCAINI
                     TGGTETGHASGTYSHWNGYKLDFSKSTCLNNYVTGTFTYIGQRGDGAAQYQSGSGNVYA
                     NEGNHWDVTYYNCGGC"
     gene            complement(901..1785)
                     /locus_tag="B9W68_RS07225"
                     /old_locus_tag="B9W68_07255"
     CDS             complement(901..1785)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612292.1"
                     /locus_tag="B9W68_RS07225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07255"
                     /product="IS982 family transposase"
                     /protein_id="WP_087772876.1"
                     /transl_table=11
                     /translation="MKTNLDALLAALYVFIDDHVAPCRRIGRPPKLTDAELLCLAVAQV
                     LLGFPSARHWIRFAHARLGHLFRYLPQQSAYNKRLNAAGPLISQVIEALARQVPSWNDD
                     LRLIDSTPLPCAASRETVKRSDLAGHAGYGYCRSHSRFFWGFRLYLVTTAEGMPVTWCL
                     ANPKLGEREVMTALLERDHHLVHQGQVILADKGFAGKEFEAFVTERLGAHLVRPDRKDE
                     PVRHGKITRVRQWIEAIIDTLKGQLSLEQHGGRSPAGVFARTGQRLLALAAGLWHNWTT
                     DATVKRSLIAYDH"
     misc_feature    1912..1926
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.79"
                     /tool="antismash"
     gene            2020..2622
                     /locus_tag="B9W68_RS07230"
                     /old_locus_tag="B9W68_07260"
     CDS             2020..2622
                     /GO_component="GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414932.1"
                     /locus_tag="B9W68_RS07230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07260"
                     /product="YceI family protein"
                     /protein_id="WP_087772877.1"
                     /transl_table=11
                     /translation="MGIFGRKNETTDATATAVNPDLAALTGTYTLDPTHTTIGFVARHA
                     MVTNVKGGFGDFTGTLTLDGSDPSNSTAEIDVAMDSVDTGNADRDGHLKNADFFKTDEF
                     PKMTFRSTKAEALGGDDYRITGDLTILGTTRPLSIDLEFNGSAKDPFGNERVGFEGTAS
                     ILRSEWGLTWNAALETGGVLVSDKIKLVLDISAIKNA"
     gene            <2744..3017
                     /locus_tag="B9W68_RS07235"
                     /old_locus_tag="B9W68_07265"
                     /pseudo=""
     CDS             <2744..3017
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507044.1"
                     /locus_tag="B9W68_RS07235"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="B9W68_07265"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="PRSSVVPTLSTADGLIHTVVRRPLIPGTDTTSLLDPYALRATRPG
                     DGVGGAGAPPGGRLALRHAPDGRRLRAGRRRAPGDDHRRRTDLRAV"
     gene            complement(3336..3701)
                     /locus_tag="B9W68_RS07240"
                     /old_locus_tag="B9W68_07270"
     CDS             complement(3336..3701)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010641993.1"
                     /locus_tag="B9W68_RS07240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07270"
                     /product="signal peptidase I"
                     /protein_id="WP_087772878.1"
                     /transl_table=11
                     /translation="MSENVYVGNAPEEAALDAGWIMGHFKAPDDPRHNEAVEIKWGVHE
                     AGERRAAWVRGEERQALLVLISGRFRMEFPGRDVVLSEQGQYVIWGKGVDHSWEAEEPS
                     VVMTVRWPSVPGYRVSP"
     misc_feature    complement(3797..3813)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.84"
                     /tool="antismash"
     gene            3829..4311
                     /locus_tag="B9W68_RS07245"
                     /old_locus_tag="B9W68_07275"
     CDS             3829..4311
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-154). E-value:
                     5.1e-20. Score: 64.3. Matches aSDomain:
                     nrpspksdomains_B9W68_RS07245_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414939.1"
                     /locus_tag="B9W68_RS07245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07275"
                     /product="SRPBCC family protein"
                     /protein_id="WP_030700183.1"
                     /transl_table=11
                     /translation="MRSTAEVSVATVIEAEPKAVYERVADVASMGRWSPECVRTAAGVG
                     PAPVGAEFKGTNKGPSGRSWSTRCRVMVARSGERFTFRVRFWGMPVATWDYRFRPVGDG
                     TATEVTETAVDQRNRLLWFLGSAVSGVWDRSAHNAETMRQTLERLRETLEAERRAG"
     aSDomain        3841..4290
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9W68_RS07245_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="5.10E-20"
                     /label="B9W68_RS07245_Polyketide_cyc2.1"
                     /locus_tag="B9W68_RS07245"
                     /protein_end="154"
                     /protein_start="4"
                     /score="64.3"
                     /tool="antismash"
                     /translation="AEVSVATVIEAEPKAVYERVADVASMGRWSPECVRTAAGVGPAPV
                     GAEFKGTNKGPSGRSWSTRCRVMVARSGERFTFRVRFWGMPVATWDYRFRPVGDGTATE
                     VTETAVDQRNRLLWFLGSAVSGVWDRSAHNAETMRQTLERLRETLE"
     gene            4463..5140
                     /locus_tag="B9W68_RS07250"
                     /old_locus_tag="B9W68_07280"
     CDS             4463..5140
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414941.1"
                     /locus_tag="B9W68_RS07250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07280"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_087772879.1"
                     /transl_table=11
                     /translation="MSDHGTTGTAGDEARAEAVRDAWARIDAWMRAHAPDSYEVLAPPA
                     DPAAVEAAQAEMGVRFPADLLASLACHDGLRHWDNCLPLRPPEPVARIVDHWQMCVEID
                     EANRADEDEPEPEGEEPWWHPQWVPWAQSDGDAQIIDMRPGPGQGRLGMAYHDDCGVFA
                     DGWPSLAAYLTEVAEVLEKGGAVGGTWAPFLTTEGELWWSLKGETQLNGEPLTPAPAPS
                     SGS"
     gene            5219..>5568
                     /locus_tag="B9W68_RS07255"
                     /old_locus_tag="B9W68_07285"
                     /pseudo=""
     CDS             5219..>5568
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414943.1"
                     /locus_tag="B9W68_RS07255"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="B9W68_07285"
                     /product="lipid II flippase MurJ"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTQGADSTVRSRTAEGRAEGAGGGLARSSLLMAVGTVVSRATGLI
                     RQVLQAAALGPGCRPVRTTRRTRCRRVSTRC"
     gene            complement(5526..5941)
                     /locus_tag="B9W68_RS07260"
                     /old_locus_tag="B9W68_07290"
                     /pseudo=""
     CDS             complement(5526..5941)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982604.1"
                     /locus_tag="B9W68_RS07260"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07290"
                     /product="VOC family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRPGLITLVVPDYDDALAFYRDRLGFALAEDTDLGAGKRWVVVVP
                     PRGGGAGPLLAKAVTPEQAARVGDQTGGRVGFFLYVEDSRTSTPGCAPPGCPSRRHPGT
                     RRTGPWPSSGTRTGTGGS"
     gene            complement(6339..7151)
                     /locus_tag="B9W68_RS07265"
                     /old_locus_tag="B9W68_07295"
     CDS             complement(6339..7151)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642004.1"
                     /locus_tag="B9W68_RS07265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07295"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_179230500.1"
                     /transl_table=11
                     /translation="MADTTDAEGLTVGQVSARLDVTVRALHHWDEIGLARPSLRTPAGY
                     RLYTVPDLERLHRIVVYRELGLGLDKIRAVLDDAATDVPAALRAQRAQIAARIDRLRQL
                     GAGLDRMIDAHERGLLLTAEQQAAIFGPGWSPDGPVQARQRYGDTTQWRQYAERSASRT
                     PEEWQAVADDVARLERALGEAMDSGVTPGSPEANHLAERHREVFASYFPLSRQMQVCLG
                     RMYEEDPGFAAHYDAIRPGLATWFRRLVDAAARAHGIDPDTATWEEDR"
     gene            complement(7144..7686)
                     /locus_tag="B9W68_RS07270"
                     /old_locus_tag="B9W68_07300"
     CDS             complement(7144..7686)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005318305.1"
                     /locus_tag="B9W68_RS07270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07300"
                     /product="VOC family protein"
                     /protein_id="WP_087772881.1"
                     /transl_table=11
                     /translation="MSDDTYYNAFEISPVPSPGPDAVPPEPFRGIYGMPAFVNIPTTDL
                     AASVEFWTRGLGFFELFSIPGTLVHLRRWAFQDVLLVAAESVPEQPPAMSFSFSGVLSQ
                     VDSLVEACRALRPDAVEGPRDTPWNTRDVEVITPENARIVFTAAKPFDPDTQEARNLEA
                     IGITPPGETPGDNERHG"
     gene            7896..8219
                     /locus_tag="B9W68_RS07275"
                     /old_locus_tag="B9W68_07305"
     CDS             7896..8219
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893452.1"
                     /locus_tag="B9W68_RS07275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07305"
                     /product="hypothetical protein"
                     /protein_id="WP_256967983.1"
                     /transl_table=11
                     /translation="MIDGLSAGTLAELARLERTRTSLWPGAVSEAVRAWAEHVRLPRGR
                     TWPHPGHGPCYCCPDPWESRELLDRVARALSRRGARELRRVLAGHDQLWDPAPRPYRGE
                     GPW"
     gene            complement(8299..8724)
                     /locus_tag="B9W68_RS07280"
                     /old_locus_tag="B9W68_07310"
     CDS             complement(8299..8724)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019354283.1"
                     /locus_tag="B9W68_RS07280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07310"
                     /product="ATP-binding protein"
                     /protein_id="WP_087772883.1"
                     /transl_table=11
                     /translation="MKTETGLPAHCERFYRRERRSVPAARDFTAAVLDDWDARVRRDDV
                     LLCVSELATNALLHGVPPGRGFRLFVLRADDAGVRVEVHDSGDGHPATRAPGDEAESGR
                     GLLLVSALADDWGVGERNPGKIVWCSFRPVGASCTPG"
     gene            8837..9664
                     /locus_tag="B9W68_RS07285"
                     /old_locus_tag="B9W68_07315"
     CDS             8837..9664
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018553254.1"
                     /locus_tag="B9W68_RS07285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07315"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_087772884.1"
                     /transl_table=11
                     /translation="MQQRKKSSKKVTSWEVLGKQLAEFRRVAGLTQGQLADMARVGEDT
                     IASVEQGRRRLQGDLAECLDTLLDTKRALATAVSMIPNRERFPAFAQGFVDYEQEALTI
                     QSYENHVVPGLLQTSEYAAAVFDGLYPPITRAERIERIAARMDRKAVFDRGPWPPMMSF
                     IIEEQVLHRPLGGPEVMREQLAKLREYADLDFISLQIMPTNVRTHPAVDGPIVLIETPD
                     HDHIAYIEGQRVSFLVDDPDEVSIMQQKYGMLRSQALSVDASKALLDELLGVR"
     gene            9673..9921
                     /locus_tag="B9W68_RS07290"
                     /old_locus_tag="B9W68_07320"
     CDS             9673..9921
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893458.1"
                     /locus_tag="B9W68_RS07290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07320"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_087772885.1"
                     /transl_table=11
                     /translation="MSTPRAWFKSSYSGSEGGNCVEVAYDWRKSSYSSDTGGNCVEVAA
                     HPTAVHVRDSKVPAGPVLDVAPAAWAAFVHATAGPLV"
     gene            10001..12286
                     /locus_tag="B9W68_RS07295"
                     /old_locus_tag="B9W68_07325"
     CDS             10001..12286
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414954.1"
                     /locus_tag="B9W68_RS07295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07325"
                     /product="terpene synthase family protein"
                     /protein_id="WP_256967984.1"
                     /sec_met_domain="T1TS (E-value: 2.3e-82, bitscore: 276.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFVLPDFYVPYPARLNPHLEEARAHAREWADEMGMLEGSGVW
                     DLADLEAHDYALLCAYTHPDCDGPALSLVTDWYVWVFFFDDHFLELFKRTQDREGAKAY
                     LERLPAFMPMDLADGFPEPQNPVEAGLADLWARTVPAMSEDWRRRFALSTENLLNESMW
                     ELSNINAGRVSNPLEYIEMRRKVGGAPWSAGLIEYAAQAEVPEAVAYSRPLRVLTDAFS
                     DGVHLRNDLFSYQREVEEEGELSNGVLVLERFLECTTQEAAEAVNDLLTSRLQQFENTA
                     LTELGPLFADKGLNPAESASVLAYVKGLQDWQSGGHEWHMRSSRYMNEGAVDGEAAPPT
                     PGGSPGALGAALLGGTLGTSALDVRAFFGRPARQRARSFSHVPYQRTGASLLPDFKLPF
                     PTRLSPALEQSRVDTVEWAHRMGLLVPQPGVPGSDVWDEEALAGYDFPLCAAGLHPEAD
                     LEELNLASQWLTWGTYGDDYYPAVFGRTRNFAGAKLCTDRLRDFMPVEQPTAGPVPTSA
                     LERSLADLWVRTASAMPEKARREFRQTIETMLDSWVWELDNQAIGRIPDPIDYMEMRRA
                     TFGSDLTMSLCRLRHGNIVPEEVYRSGTIQAMEKAVSDYGALINDVFSYQKEVEFEGEI
                     HNAVLVTQNFFDCDYPTGLAYVDALMNARLEQFEHIVAHELPVLYEDFQLDGAARKVLD
                     GYVRQLENWLSAILTWHRGCKRYKEEDLSHHSPGVRRVIEAAPRGIGPNGLGASSLGTA
                     AARVFAGG"
     gene            complement(12321..13694)
                     /locus_tag="B9W68_RS07300"
                     /old_locus_tag="B9W68_07330"
     CDS             complement(12321..13694)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642015.1"
                     /locus_tag="B9W68_RS07300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07330"
                     /product="hypothetical protein"
                     /protein_id="WP_087772886.1"
                     /transl_table=11
                     /translation="MLGAAGATAAPAFAAPDQGRPAAAAPVRAAPQAPAAATVSEVAKA
                     WREGPVFVDPDVSDQLSDADARDLSQEIQDSDKAIFVAVLPATFTDDVDQTMNDLRGDT
                     GITGLYVLRIGDDLHVRADESVLSQQAVRNLESRFQDTTPADEQLTGLVGNATQNMGGR
                     APTSWSSQNSVSGATWLGLGIAVVVVGGAAYTLTRRRKIRREQAQREALAKLRVVVDED
                     ITAFGEELERLDFSPYESGATDEMRGDYERGLDAYENAKSLMDHAQKPEDVREVTKALE
                     DGRFALAVLDARRSGRELPVRRPPCFFDPRHGLSVADVTWAPAGGAPREVPVCAADQAR
                     LERGEAPDIRTVESDEGGRRPYWEAGPAYGPWAGGYFGGGILPGILVGTMLGHMMMSPA
                     YAADYGSAEGFGDGGAGGGYEGGDVSGSDFDPGDFGGGGGFGDGGGFGGGGGDFGGGF"
     gene            complement(13853..15628)
                     /gene="cimA"
                     /locus_tag="B9W68_RS07305"
                     /old_locus_tag="B9W68_07335"
     CDS             complement(13853..15628)
                     /EC_number="2.3.3.21"
                     /GO_function="GO:0043714 - (R)-citramalate synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046912 - acyltransferase activity, acyl
                     groups converted into alkyl on transfer [Evidence IEA]"
                     /GO_process="GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cimA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470910.1"
                     /locus_tag="B9W68_RS07305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07335"
                     /product="citramalate synthase"
                     /protein_id="WP_256967985.1"
                     /sec_met_domain="HMGL-like (E-value: 2.6e-44, bitscore:
                     150.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSQATPEEPAERAPSAATKPQVARDVRGGDGARPAPAATPAGAP
                     ASAPSAADAAVERPLHIFDTTLRDGAQREGINLSVADKLTIARHLDDFGVGFIEGGWPG
                     ANPRDTEFFARAREEITFRHAQLVAFGATRRAGGSAADDLQVKALLDSGAPVVTLVAKA
                     HDRHVELALRTTLDENLEMVRDTVSHLRAQGRRVFVDCEHFFDGYAANPAYAKAVVRAA
                     SEAGADVVVLCDTNGGMLPAQIQAVTATVLADTGARLGIHAQDDTGCAVANTLAAVDAG
                     ATHVQCTANGYGERVGNANLFPVVAALELKYCRTVLPEGALAEMTRISHAIAEVVNLTP
                     STHQPYVGVSAFAHKAGLHASAIKVDPDLYQHIDPELVGNRIRMLVSDMAGRASIELKG
                     KELGIDLGGDRALVGRVVERVKERELAGYSYEAADASFELLLRDELRRGADGAGDAAPS
                     RFFRVESWRAITENRPDGTHANEATVKLWAKGERLLATAEGNGPVNALDRALRVALERI
                     YPELAKFALRDYKVRILEGRSGTDSTTRVLISTGGGDAEWSTVGVAENVIAASWHALED
                     AYTYGLLRAGVEPAE"
     gene            complement(<15919..>16310)
                     /locus_tag="B9W68_RS07315"
                     /old_locus_tag="B9W68_07345"
                     /pseudo=""
     CDS             complement(<15919..16310)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951045.1"
                     /locus_tag="B9W68_RS07315"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="B9W68_07345"
                     /product="alpha-ketoglutarate transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQHAGSFWPALGLSLLALLIITATPRSTPA"
     gene            complement(16316..17395)
                     /locus_tag="B9W68_RS07320"
                     /old_locus_tag="B9W68_07350"
     CDS             complement(16316..17395)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414969.1"
                     /locus_tag="B9W68_RS07320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07350"
                     /product="agmatine/peptidylarginine deiminase"
                     /protein_id="WP_087772887.1"
                     /transl_table=11
                     /translation="MPDAPAPSLRGTLPPGFRMPPEWAPHLRTWMAWPGPNPTFATEAE
                     LASAESAWAEVARTVRRFEPVTVLAGPGRAEGARALLGPGVDVVERPLDDAWMRDIGPT
                     FVTRAEDGARAALDWTFNGWGAQEWARWEHDAKIGGEVAALAGVTAYRTGLVNEGGGLH
                     VDGEGTVLLTETVQLDPDRNPGLSRAEAEAEIHAGLGTSKAVWLPRGLTGDYGRFGTRG
                     HVDIVAAFARPGVVVAHTQPDPAHPDHEVCKEITGVLRAARDAAGRRLEVVEVPAPTVL
                     EVDGAWADYSYINHYLCNGGVVLCAFDDPRDAEAAALFRRLFPDRTIVPVDARPVFAAG
                     GGIHCITQQEPAPARGTRG"
     gene            complement(17404..19206)
                     /locus_tag="B9W68_RS07325"
                     /old_locus_tag="B9W68_07355"
     CDS             complement(17404..19206)
                     /EC_number="3.5.1.5"
                     /GO_function="GO:0009039 - urease activity [Evidence IEA]"
                     /GO_process="GO:0043419 - urea catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470907.1"
                     /locus_tag="B9W68_RS07325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07355"
                     /product="urease subunit alpha"
                     /protein_id="WP_256967986.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 8.4e-47, bitscore:
                     158.5, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHPADPALPDDLTPRPRAFPHLARTPHGRRTAPGEAAGASDPYA
                     YAAVHGPRAGDRVRLGDTGLTVRVEADAQRPGDEFLAGFGKTARDGLHLRAAAVRDTCD
                     LVISNVLVIDAVLGIRKVSIGLREGRIHAVGRAGNPDTLDGVDVVVGTGTTIVSGEGLI
                     ATAGAIDTHVHLLSPRVMEASLASGVTTIIGQEFGPVWGVGVNSPWALRHAFAAFDAWP
                     VNIGFLARGSSSHAAPLVEALAEGGACGFKVHEDMGAHTRALDTALRVAEEYDVQVALH
                     SDGLNECLSVEDTLQVLDGRTIHAFHIEGCGGGHVPDVLRMAGVPNVIGSSTNPTLPFG
                     RDAVAEHYGMIVSVHDLKPGLPGDAAMARDRIRESTMGAEDVLHDLGAIGITSSDAQGM
                     GRAGETIRRTLQLAAKMKRERGPLDGDGEGDDNARVLRYLAKLTVNPARAHGLSHEVGS
                     LEPGKLADIVLWRPEYFGAKPQLVLKSGFPAYGVTGDPNAATDTSEPLVLGPQFGAHGA
                     AAAELSVAFVAGAAVGFGADALPTRRRRVPVRGTRNIGPADLLLNSRTGQVDVDARTGL
                     VTLDGDPVRSGPADSVSLNRLYFL"
     gene            complement(19203..19940)
                     /gene="ureA"
                     /locus_tag="B9W68_RS07330"
                     /old_locus_tag="B9W68_07360"
     CDS             complement(19203..19940)
                     /EC_number="3.5.1.5"
                     /GO_function="GO:0009039 - urease activity [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0019627 - urea metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ureA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642020.1"
                     /locus_tag="B9W68_RS07330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07360"
                     /product="urease subunit gamma"
                     /protein_id="WP_087772888.1"
                     /transl_table=11
                     /translation="MRLTPTERDRLLIFNAAQLARARQARGLRLNVPEATALISDTVCE
                     AARDGARLAEAVAAGRAVLKPNDVLPGVADVLTEIQVEAVFEDGSRLAVLADPIGGGHT
                     GDQAPGALLPGPPHAEPGPVLTLLVTNTATVPVSVTSHFHFFEANPRLSFDRAAAYGMR
                     LAVPAGSSLRFGPGETREAGLVEIGGARVVIGFAGLVDGPLDAPGARAEALRRAAACGY
                     LGAETPGTDSAPPGATPVPETDA"
     gene            complement(20410..21498)
                     /locus_tag="B9W68_RS07335"
                     /old_locus_tag="B9W68_07365"
     CDS             complement(20410..21498)
                     /EC_number="2.6.1.42"
                     /GO_function="GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA]"
                     /GO_process="GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_4 (90-343). E-value: 4.6e-28.
                     Score: 90.5. Matches aSDomain:
                     nrpspksdomains_B9W68_RS07335_Aminotran_4.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951042.1"
                     /locus_tag="B9W68_RS07335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B9W68_07365"
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="WP_087772889.1"
                     /transl_table=11
                     /translation="MTTPTIELKPSAHPLPEAEREAILARPGFGRHFTDHMVTVKWTEG
                     RGWHDGQLVPYGPLSLDPATNVLHYAQEIFEGLKAYRRPDGAVATFRPDANARRFQASA
                     RRMAMPELPVETFIEACDLLVAQDKAWVPPHGGEESLYLRPFMIATETGLGVRPANEYL
                     FVVIASPAGAYFPGGVKPVSIWLSENRVRAVPGGVGDAKTGGNYAASLLAQAEAAAEGC
                     DQVAYLDAVEHKWVEELGGMNLCFVYGDRLVTPTLTGSLLAGVTRDTLLSLAADLGYRA
                     EEGRVSIDQWREDSRSGALTEVFACGTAAVITPVGRVKTATDEWTQGTGEPGEVTLRLR
                     EALLALQTGRTEDRHGWMHPLG"
     aSDomain        complement(20470..21228)
                     /aSDomain="Aminotran_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B9W68_RS07335_Aminotran_4.1"
                     /evalue="4.60E-28"
                     /label="B9W68_RS07335_Aminotran_4.1"
                     /locus_tag="B9W68_RS07335"
                     /protein_end="343"
                     /protein_start="90"
                     /score="90.5"
                     /tool="antismash"
                     /translation="FRPDANARRFQASARRMAMPELPVETFIEACDLLVAQDKAWVPPH
                     GGEESLYLRPFMIATETGLGVRPANEYLFVVIASPAGAYFPGGVKPVSIWLSENRVRAV
                     PGGVGDAKTGGNYAASLLAQAEAAAEGCDQVAYLDAVEHKWVEELGGMNLCFVYGDRLV
                     TPTLTGSLLAGVTRDTLLSLAADLGYRAEEGRVSIDQWREDSRSGALTEVFACGTAAVI
                     TPVGRVKTATDEWTQGTGEPGEVTLRLREAL"
     misc_feature    22047..22060
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.86"
                     /tool="antismash"
ORIGIN
        1 cattcgactg ccgggagggg gtgcgcgtta tggggttccg acaaaggccg gcgggtcgcg
       61 gttctctcac ccacccgtag ggaccccaca agcagctgcg ccgggacgag gggcgtcgca
      121 cggcacgggt ccgcccgccg agggtagcgg cggacggacc cgggagaaaa acggtggcct
      181 gcgaggcggg tcagcagccg ccgcagttgt agtaggtcac gtcccagtgg ttgccctcgt
      241 tggcgtagac gttgccggag cccgactggt actgggcggc gccgtcgccg cgctggccga
      301 tgtaggtgaa ggtgccggtg acgtagttgt tcaggcaggt gctcttggag aagtcgagct
      361 tgtagccgtt ccagtgcgag taggtgccgc tggcgtggcc ggtctcggtg ccgccggtga
      421 tgttgatggc gcagccgctc gccgacttca gggtctgggc gccttgggcg gtggcgagat
      481 tcagctggtc gaaggaggta caggtcgaga cgttgcggtt ggagcagcct cccgaggacg
      541 accaggtgat gccggaggag gagaaccgcg aggtggcctg cgcgtgggtg atcttggtgg
      601 cggccgcgcc gacctcggcg acggtggagg tgggggccgg tgcggcggtg gcggcggtgg
      661 cggtgccgat gacgccgaac ccggctccgg cgacgagggc tagggcgctc agcgccgagc
      721 ggatcttcat gggggtcctc cttgcggggc gcgtgcggcg cacgcggcgg tggggggtgc
      781 gtgggggtgg tgcggaggcc gtgcggggcg gggcagacgc atcgtgcccg agttctacgc
      841 gggtcgccag agggccttac cgatcagttc cggccaacta gatgaatgag tccgatgttc
      901 tcagtggtcg taggcgatca gtgatcgttt gactgtggcg tcggtggtcc agttgtgcca
      961 gaggccggcg gcgagggcga ggagtctttg gccggtgcgg gcgaagactc cggccggtga
     1021 tctgccgccg tgttgttcga ggctgagctg gcctttgagg gtgtcgatga tggcctcgat
     1081 ccactggcgg acccgggtga tctttccgtg tcggaccggc tcgtccttgc ggtcgggccg
     1141 caccagatgg gcgccgagcc gttcggtgac gaacgcttcg aactccttcc cggcgaagcc
     1201 cttgtcggcc aggatcacct gcccttggtg gacgaggtgg tggtcgcgct ccaaaagtgc
     1261 ggtcatcacc tcccgctcgc cgagtttcgg gttggccagg caccaggtga cgggcatgcc
     1321 ctcggcggtg gtgaccaggt agagccggaa gccccagaag aacctggagt ggctgcggca
     1381 gtagccgtaa ccggcgtgcc cggccaggtc ggagcgcttg acggtctccc tcgacgcggc
     1441 gcagggcagc ggggtggagt cgatcagccg caggtcgtcg ttccaggacg ggacctgccg
     1501 ggcgagtgcc tcgatcacct ggctgatcag cggcccggct gcgttgaggc gcttgttgta
     1561 ggcggactgc tggggcaggt agcggaacag gtggcccagg cgggcgtgtg cgaagcggat
     1621 ccagtgtcgg gccgagggga agccgagcag gacctgggcg acggccaggc acagcagttc
     1681 ggcgtccgtg agtttcgggg gtcgcccgat ccggcgacaa ggcgccacat ggtcgtcgat
     1741 gaacacgtac agtgccgcca gaagggcgtc caggtttgtc ttcacacact gaccaacggg
     1801 cgcccttcgc catggtcgcg accagcccag acatcggact cattcatcta gggggcgcgt
     1861 tcggcgcgcg tgaatccacc tggagggccg cgcccgaaga cggccggacg gaagatgttg
     1921 aaaattgaac cgaaacgcgt taccttcgga ctcgttgaaa cttcaacatc ccctccccgc
     1981 tccggagacc gcccggagca cgcccccaag gagcacccca tgggcatctt cggccgcaag
     2041 aacgagacca ccgacgccac cgccaccgcc gtcaaccccg acctggccgc gctgaccggc
     2101 acgtacacgc tcgacccgac gcacaccacg atcggcttcg tggcccggca cgccatggtc
     2161 accaacgtca agggcggctt cggcgacttc accggcacgc tgacgctgga cggctccgac
     2221 ccgtccaact ccaccgccga gatcgacgtg gccatggact ccgtcgacac cggcaacgcg
     2281 gaccgcgacg gccacctgaa gaacgccgac ttcttcaaga ccgacgagtt cccgaagatg
     2341 accttccgct cgaccaaggc ggaggcgctc ggcggcgacg actaccggat caccggcgac
     2401 ctgaccatcc tcggcaccac ccgcccgctc tccatcgacc tggagttcaa cggctccgcc
     2461 aaggacccgt tcggcaacga gcgcgtcggc ttcgagggca ccgcctcgat cctccgctcc
     2521 gagtggggcc tgacctggaa cgcggcgctg gagaccggcg gcgtcctcgt ctccgacaag
     2581 atcaagctgg tcttggacat ctcggcgatc aagaacgcct gacgcggacc ggcccccagg
     2641 ggcaccgggg cccgagagcc ctaccgagcg cgcccgccct ccctaccgga gggcgggcgc
     2701 tcgcgcgtac gtgcccgcct cgcgcgggtg gtgcgccctg ctgccccgct cctcggtcgt
     2761 cccgaccctc tccaccgccg acggcctgat ccacacggtc gtccggcgcc ccttgatccc
     2821 gggcacggac accacgagcc tgctggaccc gtacgcccta cgtgcaactc gacccggcga
     2881 cggggtggga ggtgcgggcg caccacctgg gggtcggctc gctcttagac acgctccaga
     2941 tggtcggcga cttcgcgccg ggcggcgtcg tgcaccaggg gacgatcacc ggcgtcgtac
     3001 ggatctccgc gcggtgagcc ggggtggcgc gcggtgagcc ggggtggcgc gcggtgcaga
     3061 aacgatcacc cggtgaccgc cgtgaacgcg ctggtcacac cccccgcgcg ccccgcacgt
     3121 tcgggtgatg ccgagggtgg cgcgggtggg gttgggtagc tgacggtcgg agccgaaggg
     3181 tgggcgcgtg ggtgtgcggg cggagcggat gccgccggcg caccccggcc gacgcgccct
     3241 ctgctgaccc ctcggcgcca ccctccgccc tctcctcacc actcaccgcc ggggtcgtct
     3301 ccccgctccg gccgggggtg gtcggagggg gcggttcagg gggagacgcg gtagcccggc
     3361 acggagggcc agcgcacggt catgacgacg gacggctcct cggcctccca ggagtggtcg
     3421 acgcccttgc cccagatcac gtactgcccc tgctcgctca ggaccacgtc ccgcccgggg
     3481 aactccatcc ggaaccgtcc gctgatgagg accaggagcg cctgccgctc ctccccgcgc
     3541 acccaggcgg cgcgccgctc gcccgcctcg tggacgcccc acttgatctc cacggcctcg
     3601 ttgtggcgcg ggtcgtccgg tgccttgaag tggcccatga tccagccggc gtccagcgcg
     3661 gcctcctcgg gggcgttgcc cacgtacacg ttctcgctca tcctccggac ggtagtacac
     3721 gtgagggtgg tctccccggg ggcccgaggg tggccgcggc gggggcggct ttggttgggt
     3781 ggggtggtct gctgacacgt tgtcgtacaa cagagggggt tgagggacgt gaggagcaca
     3841 gcggaggtct ccgtggcgac cgtgatcgag gcggagccga aggcggtcta cgagcgggtc
     3901 gccgacgtgg cgtccatggg gcggtggagt ccggagtgtg tacggacggc ggcgggcgtc
     3961 gggcccgcgc cggtgggcgc cgagttcaag gggaccaaca aggggccgag cggccggagc
     4021 tggtcgacgc ggtgccgggt gatggtggcc cgctccggcg agcggttcac cttccgggtg
     4081 cggttctggg ggatgccggt ggccacctgg gactaccgct tccgcccggt cggggacggc
     4141 accgcgaccg aggtgaccga gacggccgtg gaccagcgca accggctcct gtggttcctc
     4201 ggttcggcgg tcagcggcgt ctgggaccgc agcgcgcaca acgccgagac catgcggcag
     4261 accctggagc ggctgcgcga gaccctggag gcggagcgcc gggccggctg agcccctccc
     4321 gggcggcggc cgttgccctc tcgcgggcgt ccgggggcgg cggaacgtac gtctgccgcc
     4381 cccggacctt cccatgcggt cacgcacccc gcgactgacg gcccgtccgg cgttgtcggt
     4441 ggggtttggt gggatcggac acatgagcga tcacggaacg acggggaccg ccggggacga
     4501 ggcgcgcgcc gaggcggtgc gggacgcctg ggcgcgcatc gacgcgtgga tgcgcgccca
     4561 cgccccggac tcctacgagg tgctggcgcc gcccgccgac ccggcggcgg tcgaggcggc
     4621 ccaggccgag atgggggttc gtttcccggc ggacctcctc gcctccctcg cctgccacga
     4681 cggcctgcgc cactgggaca actgcctgcc gctgcgcccg cccgagcccg tcgccaggat
     4741 cgtcgaccac tggcagatgt gcgtcgagat cgacgaggcc aaccgcgccg acgaggacga
     4801 gccggagccc gagggcgagg agccctggtg gcacccccag tgggtcccct gggcccagag
     4861 cgacggcgac gcccagatca tcgacatgcg cccgggtccc ggccagggcc gcctcggcat
     4921 ggcctaccac gacgactgcg gcgtcttcgc cgacggctgg ccgtccctgg cggcgtacct
     4981 gaccgaggtc gcagaggtcc tggagaaggg cggggcggtg gggggaacct gggccccctt
     5041 cctgacgacc gagggggaac tctggtggtc cctcaagggc gagacccagc tcaacggcga
     5101 accgctgaca ccggccccgg cgccttcgtc cggttcctga cgccccgccg ggccggggct
     5161 caccgcaccg gcccgatccg gacgcggcac cgccgggcgc ggcacctatg ttgagcgcat
     5221 gacacagggg gcggattcca ccgtacggtc gcggacggcg gaggggcggg cggagggcgc
     5281 cggtggcggg ctggcccggt cgtcgctgct gatggcggtg gggacggtgg tgtcccgggc
     5341 gacggggctg atccggcagg tgttgcaggc ggcggcgctg gggccgggct gccggccagt
     5401 acgtacaaca cggcgaacac ggtgccgacg agtctctaca cgctgctgat cggcggagcg
     5461 ctcaacgccg ccctggcgcc ccggctcgta cgggcccggg cgacggaggc ggacggcggg
     5521 cgggcctacg aacagcggct ggtgacgctc gtcgtctgtg tcctcggctg gatcagctcc
     5581 caccggttcc cgtacgggtc ccggaagacg gccacggtcc cgtacgcctc gtgccggggt
     5641 gcctcctcga agggcacccc ggcggcgcgc agccgggcgt gctcgtgcgc gaatcctcga
     5701 cgtacaggaa gaacccgacc cggccgcccg tctggtctcc gacccgggcg gcctgctccg
     5761 gcgtgaccgc tttcgcgagg agcggcccgg ccccgccccc gcgcggcggc acgacgacca
     5821 cccagcgctt gcccgcgccg agatcagtgt cctcggccag tgcgaacccg agacggtctc
     5881 ggtagaaggc aagggcatcg tcgtagtcgg ggacaacgag ggtgatcagt cctgggcgca
     5941 tgggggcagg gtgcgcgacc gggccggttc gggccaccgc gttgtcaccc cagggcgacg
     6001 tggtccccgc cctccgccgc cccggccggc accgccgccg gccctgtgaa cacggccgct
     6061 gctccaccgg ccaccgccgt tctccacatc gccttccgcg tcatcgaacc cgccctctcc
     6121 ccacagcgtg cacaggcgcg caggcgcccc ggccggagtt tcgtccccct cggctgatgg
     6181 tgggacaggg gagggcggtg cgcggtcgtg cgcggggagg gacacgtttt gatcactgtg
     6241 gcggcacgcg ctgggggacg gaggatcggt cggtgggcgg ggcgtatgtg ggagtgggcg
     6301 gagagatgtg gtgagccgcg ctcgccgtac cgctgctctc accggtcctc ctcccaggtc
     6361 gcggtgtcgg ggtcgatgcc gtgggcccgc gcggcggcgt cgacgagtcg gcggaaccag
     6421 gtggcgaggc cggggcggat ggcgtcgtag tgggcggcga agcccgggtc ctcctcatac
     6481 atgcggccga ggcagacctg catctgccgg gagagcggga agtaggacgc gaagacctcg
     6541 cggtggcgtt cggcgaggtg gttcgcctcc gggctgccgg gggtgacacc ggagtccatc
     6601 gcctcgccga gggcgcgttc gagccgggcg acgtcgtcgg cgacggcctg ccactcctcc
     6661 ggggtgcggg aggccgagcg ttcggcgtac tgccgccatt gcgtcgtgtc cccgtagcgc
     6721 tgacgggcct ggaccggccc gtcggggctc catccggggc cgaagatcgc ggcctgttgc
     6781 tcggcggtca gcagcaggcc gcgttcgtgg gcgtcgatca tccggtcgag tccggcgccg
     6841 agttgccgga ggcggtcgat ccgggcggcg atctgggcgc gttgcgcgcg gagggcggcc
     6901 ggtacgtccg tggccgcgtc gtcgaggacg gcacggatct tgtccaggcc gaggccgagt
     6961 tcgcggtaga cgacgatgcg gtgcaggcgt tccaggtcgg ggacggtgta gagccggtat
     7021 ccggcgggtg tgcgcaggga gggccgggcc aggccgatct cgtcccagtg gtggagcgcc
     7081 cggaccgtca cgtccaggcg cgccgagacc tgaccgacgg tcaggccctc ggcgtccgtg
     7141 gtgtcagcca tgccgctcat tgtcgcccgg ggtctcgccg ggcggggtga tgccgatggc
     7201 ttccaggttg cgtgcctcct gggtgtccgg gtcgaagggc ttcgcggcgg tgaagacgat
     7261 gcgcgcgttc tcgggggtga tgacttccac gtcacgggtg ttccagggcg tgtcccgcgg
     7321 cccctcgacc gcgtccggac gcagcgcacg gcatgcctcg acgagggagt cgacctggct
     7381 gagcacgccg gagaaactga agctcatcgc cggcggctgt tccggaacgc tctccgccgc
     7441 cacgagaagt acgtcctgga acgcccatcg gcgcagatgg acgagggtgc ccgggatgct
     7501 gaacagctcg aagaagccga gcccccgcgt ccagaactcc accgacgccg ccagatcggt
     7561 cgtcgggatg ttcacgaagg cgggcattcc gtagatgccg cgaaacggct ccggcgggac
     7621 tgcgtcgggc ccgggagagg gcacggggct gatctcgaac gcgttgtagt aggtgtcgtc
     7681 gctcatgtgc cccagcctcg ggcctcacgc aacgtgaggg tcaagccggg atcgtgcctc
     7741 ctccggaccc gggagaaaag accgggcatc cggggcacgc ccgtgccagg ctggccgcat
     7801 gacgacctac cgccgaaagg cccgtgccgc gtaagccgcc gggaagggtg cggaccggac
     7861 tcccccggcc gcgcaggccc tacgagaaat cgcccgtgat cgacgggctg tcggccggaa
     7921 cgctcgccga gctggcccga ctggagcgca cgcgcacctc tctctggccg ggagccgtgt
     7981 ccgaggccgt acgcgcctgg gccgagcacg tgcgactgcc gcgcggacgc acctggcccc
     8041 acccgggaca cggcccctgt tactgctgcc ccgacccctg ggagtcccgg gagctgctcg
     8101 accgggtcgc ccgcgccctg tcccggcgcg gggcgcgcga gctgcggcgc gtcctggccg
     8161 ggcacgacca gctctgggac ccggcgcccc ggccgtaccg gggcgagggc ccgtggtgag
     8221 gccggcgcgc cccggcggac cctcgcggac ctcaccccgg taccggccgt cgcggctcag
     8281 ggcgacagcg gacgggggtc atcccggcgt gcaactggcc cccacggggc ggaaggaaca
     8341 ccagacgatc ttgcccgggt tgcgctcccc caccccccag tcgtcggcga gggcggagac
     8401 caggagcagg ccccggccgg actcggcctc gtcgccgggg gcgcgggtcg cggggtgccc
     8461 gtcgccactg tcgtggacct cgacgcgtac gccggcgtcg tcggcccgga gcacgaagag
     8521 gcggaagccg cgtcccggcg ggacgccgtg gagcagggcg ttggtggcca gttcgctcac
     8581 gcagagcaag acgtcgtcgc ggcggacgcg agcgtcccag tcgtccagca cggcggcggt
     8641 gaagtccctg gctgcgggga cggatcggcg ctcgcgacgg tagaagcgct cgcagtgcgc
     8701 ggggagtccg gtttcggttt tcaccctcct acggtcaccc aacgtcacta gccttgtgca
     8761 gggcgtcgac ccgtacaaat ccgttgtacg ggtcgtgtcg ggtgcgcgac gaggcgcgtc
     8821 gggagatgga gtgcgtatgc agcagcgaaa gaagtccagc aagaaggtca cgtcgtggga
     8881 agtgctcggc aaacaactgg ccgagtttcg gcgggtggcg gggctgaccc aggggcagtt
     8941 ggcggacatg gcgagggtgg gcgaggacac catcgcctcc gtcgaacaag gcagacgacg
     9001 gcttcaaggc gacttggcgg aatgcctgga cacgctcctg gacacgaaac gggcactggc
     9061 cacggcggtg tcaatgatcc cgaaccgtga gcgcttccct gctttcgccc agggattcgt
     9121 ggactacgaa caggaagcac tgacgatcca gtcgtacgag aaccacgttg tcccaggctt
     9181 gcttcaaacg tccgagtacg cagcggcggt attcgatggg ctgtacccac ccatcacacg
     9241 ggctgagcgt attgagcgga tcgcggcacg catggaccgg aaggctgttt tcgaccgggg
     9301 accctggccc ccaatgatga gcttcatcat tgaagagcag gttcttcacc ggcccctggg
     9361 agggccggaa gtgatgcgtg aacagctggc gaaactgcgc gagtatgcag atcttgactt
     9421 catcagcctc cagatcatgc ccacgaacgt tcgaactcac cctgctgtcg acgggccgat
     9481 agtgctgatc gagacgccag accatgacca catcgcgtac atcgaggggc aacgtgtcag
     9541 cttccttgtt gacgacccgg acgaggtgag catcatgcag cagaaatatg gaatgctgcg
     9601 ctcgcaggcg ctgtccgtgg acgcaagcaa agccctgctg gatgagctgc taggagtgag
     9661 atgaagcgcg cgatgtcgac cccacgtgca tggttcaagt cgagctacag cggaagtgag
     9721 ggcggcaact gcgtcgaggt cgcctacgac tggcgcaagt ccagctacag cagcgacacg
     9781 ggcggcaact gcgtagaagt cgccgcccac cccaccgccg tccacgtccg cgactccaag
     9841 gtcccggcgg gccccgtcct cgacgtcgcc cccgccgcct gggcggcgtt cgtacacgcg
     9901 accgccggtc cactcgtatg acaacaccgc cgtccggctg acgggtcggg cgggcgggta
     9961 gtgatcgggc cgccggtatc accgtgtgga aggctcgacc gtgacacagc cctttgtcct
    10021 gcccgatttc tacgtgccgt acccggcgcg gctcaaccct catctcgaag aggcgcgtgc
    10081 gcacgcccgg gagtgggcgg acgagatggg gatgctggag gggtcgggcg tctgggacct
    10141 ggccgacctg gaggcccacg actacgcgtt gctctgcgcg tacacgcatc cggactgcga
    10201 cggtccggcg ctgtcgctgg tgaccgactg gtacgtgtgg gtcttcttct tcgacgacca
    10261 cttcctggag ctgttcaagc ggacgcagga ccgtgagggc gcgaaggcgt acctggagcg
    10321 gctgccggcg ttcatgccga tggatctggc cgacgggttc ccggagccgc agaacccggt
    10381 ggaggcgggg ctcgccgacc tctgggcgcg gacggtcccg gccatgtccg aggactggcg
    10441 ccgccgcttc gccctctcca cggagaacct gctcaacgag tcgatgtggg agctctccaa
    10501 catcaacgcg gggcgcgtct ccaacccact ggagtacatc gagatgcgcc gcaaggtcgg
    10561 cggcgcgccc tggtcggcgg ggctgatcga gtacgcggcg caggccgagg tgccggaggc
    10621 ggtggcgtac tcgcggcccc tgcgcgtgct gaccgacgcc ttctcggacg gcgtccacct
    10681 gcgcaacgac ctcttctcgt accagcggga ggtcgaggag gagggcgagc tgagcaacgg
    10741 cgtcctcgtg ctggaacggt tcctggagtg cacgacgcag gaggcggccg aggccgtcaa
    10801 cgacctgctg acctcgcgcc tccagcagtt cgagaacacc gcgctgaccg aactgggccc
    10861 gctcttcgcc gacaaggggc tgaatccggc cgagtccgcc tcggtgctgg cgtacgtgaa
    10921 ggggctccag gactggcagt cgggcggcca cgagtggcac atgcgctcca gccggtacat
    10981 gaacgagggc gcggtcgacg gggaggcggc gccgccgacg ccgggcgggt cgccgggggc
    11041 gctgggggcg gcgctgctgg gcgggaccct gggcacgtcg gcgctggacg tgcgggcgtt
    11101 cttcgggcgt ccggcgcggc agcgggcgcg cagcttctcg cacgtgccgt accagaggac
    11161 cggggcctcg ctgctgccgg acttcaagct tccgttcccg acgcggctct ccccggcgct
    11221 ggagcagtcc cgggtggaca cggtcgagtg ggcgcaccgg atggggctgc tggtgccgca
    11281 gccgggggtg cccgggtcgg acgtgtggga cgaggaggcg ctggccggct acgacttccc
    11341 gctctgcgcg gccgggctcc acccggaggc ggacctggag gagctgaacc tcgcctcgca
    11401 gtggctgacc tggggcacct acggcgacga ctactacccg gcggtcttcg gccgtacccg
    11461 gaacttcgcc ggggccaagc tctgcaccga ccggctgcgc gacttcatgc cggtcgagca
    11521 gccgacggcg gggccggtgc cgaccagcgc gctggaacgg tcgctcgccg acctgtgggt
    11581 gcggaccgcc tccgcgatgc cggagaaggc gcgccgcgag ttccggcaga ccatcgagac
    11641 gatgctggac agctgggtct gggagctgga caaccaggcc atcggccgca tccccgaccc
    11701 catcgactac atggagatgc gccgcgccac cttcggttcc gacctgacga tgagcctgtg
    11761 ccgcctgcgc cacggcaaca tcgtccccga ggaggtgtac cgctcgggca ccatccaggc
    11821 gatggagaag gccgtctcgg actacggcgc gctgatcaac gacgtcttct cgtaccagaa
    11881 ggaagtggag ttcgagggcg agatccacaa cgccgtcctc gtcacgcaga acttcttcga
    11941 ctgcgactac ccgaccgggt tggcgtacgt ggacgcgctg atgaacgcgc ggctggaaca
    12001 gttcgaacac atcgtggccc acgaactccc cgtgctgtat gaggatttcc agctggacgg
    12061 ggcggcccgg aaggtgctcg acgggtacgt gcggcagctg gagaactggc tgtcggccat
    12121 cctgacctgg caccggggct gcaagcggta caaggaggag gacctgagcc atcactcccc
    12181 cggcgtgcgg cgggtgatcg aggccgcgcc gcgcgggatc gggccgaacg ggctcggcgc
    12241 ctcgtcgctg ggcacggccg ccgcccgggt gttcgccgga gggtgacggc agcgggccgg
    12301 ggtgagcggc tccggcggtg tcagaagcct ccgccgaagt cgccgcctcc gccgccgaac
    12361 cctccgccgt cgccgaagcc gccgccgccg ccgaagtcac cggggtcgaa gtcggagccg
    12421 gagacgtcgc cgccctcgta gccgccgccc gcgccgccgt cgccgaaccc ttcggccgag
    12481 ccgtagtcgg cggcgtaggc ggggctcatc atcatgtggc cgagcatggt gccgacgagg
    12541 atgccgggga ggatgccgcc gccgaagtag ccgccggccc agggaccgta cgccggtccg
    12601 gcctcccagt acgggcgccg gccgccctcg tcggactcga cggtgcggat gtcgggggcc
    12661 tcgccccgct ccagccgtgc ctggtcggcg gcgcagacgg gcacctcgcg gggtgcgccg
    12721 ccggccgggg cccaggtgac gtcggcgacc gagaggccgt ggcgcgggtc gaagaagcac
    12781 ggcgggcggc gcaccggcag ctcacggccg ctgcgccggg cgtcgagcac ggcgagcgcg
    12841 aaccggccgt cctccagcgc cttggtcacc tcccgcacgt cctcgggctt ctgggcgtgg
    12901 tccatgagcg acttggcgtt ctcgtacgcg tcgagcccgc gctcgtagtc gccgcgcatc
    12961 tcgtcggtgg ccccggactc gtacgggctg aagtcgagcc gctccagctc ctcaccgaac
    13021 gcggtgatgt cctcgtccac cacgacccgc agcttggcca gcgcctcccg ctgggcctgc
    13081 tcgcgccgga tcttgcgccg cctggtcagc gtgtacgcgg cgccgcccac cacgacgacg
    13141 gcgatgccga gaccgagcca cgtcgcgccg gagacgctgt tctgggagga ccaggaggtg
    13201 ggggcgcggc cgcccatgtt ctgggtggcg ttgcccacga ggccggtgag ctgttcgtcg
    13261 gccggggtgg tgtcctggaa gcgggattcg aggttccgca cggcctgctg cgagagaacc
    13321 gattcgtcgg cacggacgtg caggtcgtca ccgatgcgca ggacgtacag gccggtgatg
    13381 ccggtgtcgc cgcgcaggtc gttcatggtc tggtcgacgt cgtccgtgaa ggtcgccggg
    13441 aggaccgcga cgaagatcgc cttgtcgctg tcctggatct cctgcgagag gtcacgcgcg
    13501 tcggcgtcgg agagctggtc cgagacgtcc gggtccacga agacggggcc ttcgcgccac
    13561 gccttggcca cctcggagac ggtcgcggcg gcgggggcct gcggcgccgc ccgcacgggt
    13621 gccgcggcgg cgggcctgcc ctggtcgggg gcggcgaagg cgggcgcggc cgtcgctccg
    13681 gcggcgccca gcacgagaag aggcccggac acgatgagag cgccccggcg tatggactgg
    13741 cggactacgg ctcgcctcat acctccacgc taacccgggt cgcggcgaag cgcccgaacg
    13801 ggcggcgggg cgggtgcggg ccccgccgcc cccgggcgta cgcgcgtcgg gcctactcgg
    13861 cgggctcgac cccggcgcgg agcagaccgt aggtgtaggc gtcctccagg gcgtgccagg
    13921 aggcggcgat gacgttctcg gcgacgccga ccgtcgacca ctccgcgtcg ccgccgccgg
    13981 tggagatcag gacgcgggtg gtggagtcgg tgccggagcg gccttccagg atgcggacct
    14041 tgtagtcccg cagggcgaac ttggccagct ccgggtagat ccgctccagg gcgacgcgga
    14101 gggcacggtc cagggcgttg acggggccgt tgccctcggc ggtggcgagg aggcgctcac
    14161 ccttggccca gagcttcacg gtggcctcgt tggcgtgggt gccgtcaggg cggttctcgg
    14221 tgatcgcccg ccacgactcg acgcggaaga agcgggacgg ggcggcgtcg cccgcaccgt
    14281 cggctccgcg ccgcagctcg tcgcggagca gcagctcgaa cgaggcgtcg gcggcctcgt
    14341 aggagtaccc ggccagctcc cgttccttga cgcgctccac gacgcggccg accagggcgc
    14401 ggtccccgcc gaggtcgatg cccagctcct tgcccttcag ctcgatggag gcgcggccgg
    14461 ccatgtcgga gacgagcatc cggatgcggt tgccgaccag ctccgggtcg atgtgctggt
    14521 acaggtcggg gtcgaccttg atcgcagagg cgtgcagtcc ggccttgtgg gcgaaggcgg
    14581 agacgccgac gtagggctgg tgggtggagg gggtgaggtt gacgacctcg gcgatggcgt
    14641 gcgagatgcg ggtcatctcg gcgagcgcgc cctcgggcag cacggtgcgg cagtacttca
    14701 gctccagggc cgcgacgacc gggaagaggt tggcgttgcc gacacgctcg ccgtagccgt
    14761 tggcggtgca ctggacgtgg gtggcgcccg cgtcgaccgc ggcgagggtg ttggcgacgg
    14821 cgcagcccgt gtcgtcctgg gcgtggatgc cgaggcgggc gccggtgtcg gcgaggacgg
    14881 tggcggtgac ggcctggatc tgcgcgggca gcatgccgcc gttggtgtcg cagaggacga
    14941 cgacgtcggc gccggcctcg ctggcggcgc ggacgactgc cttggcgtag gccgggttgg
    15001 cggcgtaccc gtcgaagaag tgctcgcagt cgacgaagac ccggcgtccc tgggcgcgca
    15061 ggtgggagac ggtgtcgcgg accatctcca ggttctcgtc gagggtggtg cgcagggcca
    15121 gctcgacgtg gcggtcgtgg gccttggcga ccagggtgac gaccggggcg ccggagtcga
    15181 ggagcgcctt gacctggagg tcgtcggcgg cgctgccgcc cgcgcggcgg gtggcgccga
    15241 aggcgacgag ctgcgcgtgg cggaaggtga tctcctcgcg ggcgcgggcg aagaactcgg
    15301 tgtcgcgcgg gttggcgccg ggccagccgc cctcgatgaa gcccaccccg aagtcgtcca
    15361 ggtgccgggc gatggtcagc ttgtcggcga cgctgaggtt gatgccctcc cgctgcgcgc
    15421 cgtcgcggag cgtggtgtcg aagatgtgca gggggcgctc gacggcggcg tcggcggcgg
    15481 acggggcgga ggcgggggct ccggcgggcg tcgcggcggg tgcggggcgc gccccgtcgc
    15541 cgccccgtac gtcgcgcgcg acctgcggtt tcgtcgcggc cgacggggcg cgctcagcgg
    15601 gttcctcggg ggtggcctgg ctggtcatgc ggtggtgact cctgtcgggt gagtggctcc
    15661 ggaatgcttg gctccacttg cccccatcct ctcgtgcgcc tcgccgcggc ccggtcgggg
    15721 ccgacaaacg aaaagacccc tcgcgggtgc gagaggtctg cgcgcgggtc tggggcacgg
    15781 tggccgcgtc gcacgtggtg gtgcggggcg gtcactgcgg accggcgcgc ctgctgccga
    15841 taatcatggc gaacgtgggc acgggggcag tctcccacag agactccccc gtgccacgag
    15901 gtgtctcagg atgcgagcgg ggcgtaccgt tttcgcgggc ggggcggccg gggaggcgga
    15961 accggccccg gcggagggcg ggcccgtctc ggcaccgacc cggttgaggt cgatgtcccg
    16021 ggtctccttc atcgccaggt ggacgacgag cgagacggcg gcacaccccg ccacgtacca
    16081 gtggtagccg gactccagcc cgccgtcctt ggcccagagc gcgacgtact cggcggtggc
    16141 gccgaagggg gcgttgccga gggcgtaggg cagggcgacg cccggcgcgc ggatgccggt
    16201 ggggaggagt ccggccttca cgcgggcgtt gatcgaggtg tagccgtgat gatgagcagc
    16261 gccaggagcg agaggccgag cgccggccag aacgacccgg cgtgctggag cggtctcagc
    16321 cccgtgtacc ccgggccggt gccggttcct gctgggtgat gcagtggatg ccgccgccgg
    16381 ccgcgaagac cgggcgggcg tcgacgggga cgatggtgcg gtccgggaag aggcggcgga
    16441 agagcgcggc ggcctcggcg tcgcgcgggt cgtcgaaggc gcagaggacg accccgccgt
    16501 tgcacaggta gtggttgatg tacgagtagt cggcccacgc cccgtccacc tccagcacgg
    16561 tgggcgcggg cacctcgacc acctccaggc ggcggcccgc cgcgtcccgg gcggcgcgca
    16621 gcacgccggt gatctccttg cagacctcgt ggtcggggtg ggccgggtcg ggctgggtgt
    16681 gcgccacgac cacgccgggc cgggcgaacg cggcgacgat gtcgacgtgg ccgcgcgtcc
    16741 cgaaccgccc gtagtcaccg gtcagcccgc gcggcagcca caccgccttg ctggtaccga
    16801 gccccgcgtg gatctcggcc tcggcctcgg cccggctcag cccggggttg cggtccgggt
    16861 cgagctggac ggtctcggtg agcagcacgg tgccctcccc gtcgacgtgc agcccgcccc
    16921 cctcgttgac cagccccgtc cggtacgccg tgaccccggc cagcgcggcg acctcaccgc
    16981 cgatcttcgc gtcgtgctcc cagcgggccc actcctgcgc accccagccg ttgaacgtcc
    17041 agtcgagcgc ggcccgggcg ccgtcctccg cacgggtgac gaaggtgggg ccgatgtccc
    17101 tcatccaggc gtcgtccagc gggcgttcga ccacgtcgac gccgggaccg aggagcgcgc
    17161 gggcgccttc ggcgcggccg ggcccggcga ggacggtgac cggttcgaag cggcgtacgg
    17221 tgcgggccac ctcggcccag gcgctttcgg ccgaggcgag ttcggcctcg gtggcgaagg
    17281 tcgggttggg gccgggccag gccatccagg tgcgcaggtg cggggcccac tcgggcggca
    17341 tgcggaagcc cggcgggagg gtgccgcgca gggacggggc gggggcgtcg ggcatggcgg
    17401 tcctcagagg aagtagaggc ggttgaggct gacggagtcg gcggggccgg agcggaccgg
    17461 gtcgccgtcg agggtgacca ggccggtgcg ggcgtccacg tcgacctggc cggtgcggga
    17521 gttgaggagg aggtcggcgg ggccgatgtt ccgggtgccg cgtacgggga cgcggcgcct
    17581 gcgggtcggc agggcgtcgg cgccgaaacc cacggctgcg cccgcgacga aggcgacgga
    17641 gagctcggcg gcggccgccc cgtgcgcgcc gaactggggt ccgaggacga ggggttcgct
    17701 ggtgtcggtg gcggcgttgg ggtcgccggt gacgccgtag gcggggaagc cggacttcag
    17761 gacgagctgg ggcttggcgc cgaagtactc ggggcgccac agcacgatgt ccgccagctt
    17821 gccgggctcc agcgagccga cctcgtggga gaggccgtgc gcgcgggccg ggttgacggt
    17881 cagtttggcc aggtagcgca ggacacgggc gttgtcgtcg ccctcgccgt cgccgtccag
    17941 cgggccgcgt tcgcgcttca tcttggcggc gagctggagg gtgcggcgga tcgtctcgcc
    18001 ggcccgcccc atcccctgcg cgtcggagga ggtgatgccg atggcgccca ggtcgtgcag
    18061 gacgtcctcg gcgcccatcg tcgactcgcg gatgcggtcg cgggccatcg cggcgtcgcc
    18121 gggcagcccg ggcttgaggt cgtggaccga gacgatcatg ccgtagtgct cggcgacggc
    18181 gtcccggccg aagggcagcg tcggattggt ggaggagccg atgacgttcg gcacacccgc
    18241 catgcgcagc acgtcgggga cgtggccgcc gccgcacccc tcgatgtgga aggcgtggat
    18301 ggtgcggccg tcgagcacct ggagggtgtc ctcgacggag aggcattcgt tgaggccgtc
    18361 gctgtgcagg gccacctgca cgtcgtactc ctcggcgacg cgcagcgcgg tgtccagcgc
    18421 ccgggtatgc gcccccatgt cctcgtgcac cttgaacccg cacgccccgc cctccgccag
    18481 cgcctcgacc agcggcgcgg cgtgggagga ggaaccccgg gcgaggaacc cgatgttgac
    18541 gggccaggcg tcgaaggcgg cgaaggcgtg gcgcagggcc cacggcgagt tcacgccgac
    18601 gccccagacg gggccgaact cctggccgat gatcgtggtc acgcccgagg cgagggaggc
    18661 ctccatgacg cggggcgaga gcaggtgcac atgggtgtcg atcgccccgg cggtcgcgat
    18721 cagcccctcc cccgacacga tcgtggtgcc ggtaccgacc accacgtcga ccccgtcgag
    18781 cgtgtccggg ttccccgcgc gcccgacggc atggatacgg ccctcgcgga ggccgatcga
    18841 gactttgcgg atgccgagca ccgcgtcgat caccagcacg ttgctgatca ccaggtcgca
    18901 ggtgtcgcgc acggcggcgg cccgcaggtg cagcccgtcc cgcgccgtct tcccgaaccc
    18961 ggccaggaac tcgtcccccg gccgctgcgc gtcggcctcg acccgcaccg tcagccccgt
    19021 gtcaccgagc cgcaccctgt cccccgcgcg agggccgtgg acggcggcgt aggcgtaggg
    19081 gtcggaggcg ccggccgcct cgccgggcgc ggtacggcgg ccgtgcgggg tgcgggccag
    19141 gtgcgggaag gcgcgggggc gcggggtgag gtcgtcaggg agggccggat cggcggggtg
    19201 gctcatgcgt cggtctccgg gacgggggtg gcgccgggcg gagcggagtc cgtcccgggc
    19261 gtttcggcgc cgaggtagcc gcaggcggcg gcgcggcgca gggcctcggc gcgggcgccg
    19321 ggtgcgtcca gcgggccgtc gaccagcccg gcgaagccga tgacgacgcg cgccccgccg
    19381 atctccacca gccccgcctc gcgggtctcg cccgggccga agcggagcga ggagccggcc
    19441 gggacggcca ggcgcatgcc gtaggcggcg gcccggtcga agctcaggcg cgggttggcc
    19501 tcgaagaagt ggaagtgcga ggtgacgctg accgggaccg tggcggtgtt ggtgaccagg
    19561 agggtcagca cggggcccgg ctcggcgtgg ggcgggcccg ggagcagggc gccgggcgcc
    19621 tggtcgccgg tgtggccgcc gccgatggga tcggccagca cggcgagccg ggacccgtcc
    19681 tcgaagaccg cctcgacctg gatctcggtc agcacgtcgg cgacgcccgg cagcacatcg
    19741 ttcggtttga gcaccgcccg ccccgccgcc accgcctccg ccagccgcgc cccgtcccgc
    19801 gccgcctcac agaccgtgtc cgagatgagc gcggtcgcct ccggcacgtt cagccggagc
    19861 ccgcgcgcct gccgggcacg ggcgagctgg gcggcgttga agatcaggag gcggtcgcgt
    19921 tcggtggggg tcaggcgcat gggggtcctg gaggggtggg gcgggcgcgg gcgatggagc
    19981 gtcaccctat ctaaagcttt taggttttcc catggatggc ggacggcagg gcgggcgctt
    20041 ggctcggagg cggccggcgg gagccctcag aggcggggcc gggtaagggg cggccccgag
    20101 tccgggtaag gggcagcccc ggaccgtcgc cccgtacctg cggcgccgcg tggagggtcg
    20161 cacaccgcgc gccacgtgcc tcgtgaagcc gcaggtcgcg cgccccgtga ccgccccgta
    20221 cgccgcgcgc cccgccacgg cgcaggtaag cccgacgccg cgacggcacc ccttaccgaa
    20281 gccagcgccg tccccgaccc gaaacggccc gccgcccccg catccgctgc ggggacgacg
    20341 ggccgtcccg gtcgtccgat cgacccggtg ccaggcgctc ccacgcgccc ggcaccggac
    20401 cttcaagact cagcccagcg ggtgcatcca cccgtggcgg tcctccgtgc ggcccgtctg
    20461 gagggcgagg agggcctcgc ggaggcggag ggtgacctcg ccgggttcgc cggtgccctg
    20521 ggtccactcg tcggtggcgg tcttgacccg gccgacgggt gtgatgacgg cggccgtgcc
    20581 gcaggcgaag acctcggtga gggcgccgct gcggctgtcc tcgcgccact ggtcgatgga
    20641 gacgcggccc tcctcggccc ggtagccgag gtcggcggcg agggagagga gggtgtcgcg
    20701 ggtgacgccg gcgaggaggg agccggtgag ggtgggggtg acgaggcggt cgccgtagac
    20761 gaagcagagg ttcatgccgc ccagttcctc gacccacttg tgctcgaccg cgtcgaggta
    20821 ggcgacctgg tcgcagccct cggcggcggc ctcggcctgg gcgaggaggg aggcggcgta
    20881 gttgccgccg gtcttggcgt cgccgacgcc gccgggcacg gcgcggacgc ggttctcgga
    20941 gagccagatc gagacgggct tgacgccgcc ggggaagtac gcgccggccg gggaggcgat
    21001 gaccacgaag aggtactcgt tggcgggccg gacgcccagc ccggtctccg tggcgatcat
    21061 gaagggccgc aggtagaggg attcctcgcc gccgtgcggc gggacccacg ccttgtcctg
    21121 ggccaccagc aggtcgcacg cctcgatgaa ggtctccacg ggcagctcgg gcatggccat
    21181 gcggcgcgcg gaggcctgga agcggcgggc gttggcgtcg gggcggaagg tcgccacggc
    21241 gccgtcgggg cggcggtacg ccttgagccc ctcgaagatc tcctgggcgt agtggaggac
    21301 gttggtggcg gggtcgaggg agagcggccc gtaggggacg agctggccgt cgtgccagcc
    21361 gcggccctcg gtccacttca cggtgaccat gtggtcggtg aagtgccggc cgaaaccggg
    21421 gcgggcgagg atcgcctcgc gctcggcctc cgggagcggg tgcgcggagg gcttcagttc
    21481 gatcgtcggc gtcgtcatga gtggtgtcct tcacgtgtgg tggtgacgga ccgcgctcac
    21541 gcccgtacct ctgagtggtg cgtgtccggg gtgctgtctc gcactccggt cagctgtgca
    21601 ccacacggac gtccgggtat cgcctcattt tccgcggccc cacgttcgat tatcgcgccg
    21661 gagggggcgg tgagggaacg ccgaggagtc caccgccccg tcgaatgtgt cacgcggcgg
    21721 agcggcaggg ggtgcggggt gagcgcgggc cctgggttgt cgcacccggg gccgcccacg
    21781 aggaagccgc cgggttgtcc cgtaggggac ccggcggctt cgggtgtcgc gcgccgggtc
    21841 agccggctac tcgtccggcg agcgcgtcgc cgatggcgtc ggtggtccgc gcggttccgt
    21901 cgcgctccgc gaggtcggcg gagacggcct cctcgatgcg ggcggcctgg gccttgtagc
    21961 cgaggtgacg cagcaggagg gcgacggaga ggatggtggc ggtcgggtcg gccttgccct
    22021 gcccggcgat gtcgggggcg gagccgtgga ccggctcgaa catcgacggg aaggcgcccg
    22081 tcgggttgat gttgccggag gcggccaggc cgatgccgcc ggtgacggcc gcggcgaggt
    22141 cggtgatgat gtcgccgaag aggttgtcgg tgacgatgac gtcgaaccgc tcgggctggg
    22201 tgacgaagaa gatcgtcgcg gcgtcgacgt gcaggtagtc ggtggtgacg tccgggtact
    22261 cggcggcgac cttgtcgaag gtgttc
//
